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Air-supported structures are widely used as public buildings. Air-supported structures are soft and most traditional fire-fighting installations cannot be used in them. Existing design specifications only specify the fire resistance of the materials to be used for air-supported structures and there is no fire resistance design method for air-supported structures. The destruction process of air-supported structures can be divided into three stages: pre-fracture, leakage, and collapse. Theorical and numerical models were used to research the time span of all those stages. A framework to estimate the collapse and evacuation time was proposed in this paper. Air-supported structures with different spans were researched in this paper, and we found that the height of a structure has a significant influence on its fire resistance. The evacuation time increased by more than 52 times when the structure's span increased from 20 m to 80 m. The pre-fracture stage contributed to more than 90% of the evacuation time when the span of structure was larger than 80 m. [ABSTRACT FROM AUTHOR]