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Start Over Author "Frampton, Jon" Topic collagen Topic genetic disorders

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1. Characterization of the c-Myb-responsive Region and Regulation of the Human Type I Collagen α2 Chain Gene by c-Myb.

Author

Luchetti, Michele M., Paroncini, Paolo, Majlingova, Petra, Frampton, Jon, Mucenski, Michael, Baroni, Silvia Svegliati, Sambo, Paola, Golay, Josee, Introna, Martino, and Gabrielli, Armando

Subjects
*COLLAGEN, *GENETICS, *GENETIC disorders
Abstract

Characterizes the c-Myb-responsive region and regulation of the human type I collagen alpha2 chain gene by c-Myb. Identification of four Myb-binding sites in the promoter; Transactivation assays on wild type and mutant promoter-reporter constructs; Expression of fibronectin and type III collagen; Mechanisms in the pathogenesis of several fibrotic disorders.

Published
2003
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