1. Associations of Major Lifetime and Everyday Discrimination with Cognitive Function among Middle-Aged and Older Adults.
- Author
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Chen R, Byrd DR, Whitfield KE, and Williams DR
- Subjects
- Humans, Female, Male, Middle Aged, Chicago, Aged, Adult, Cognition
- Abstract
Objectives: We investigated the associations of lifetime and everyday discrimination with cognitive function., Methods: Data were from the Chicago Community Adult Health Study (n=2952, mean age=43 years [SD=17]). We fitted multivariable linear regression models to quantify the discrimination-cognition associations., Results: Major lifetime ( β
1 vs 0 episodes of discrimination = 0.56; 95% CI, 0.15-0.96; β2+ vs 0 episodes of discrimination = 0.64, 95% CI, 0.31-0.97) and everyday ( β =0.10, 95% CI, 0.06-0.14) discrimination were positively associated with cognition, and these associations did not differ by race/ethnicity. Among older adults, major lifetime discrimination, but not everyday discrimination, was positively associated with cognition ( β2+ vs 0 episodes of discrimination =1.79; 95% CI, 0.79-2.79)., Discussion: Measurement and selection bias may partially explain the counterintuitive study findings. We call for longitudinal research to further investigate the discrimination-cognition relationship., Competing Interests: Conflict of Interest: No conflict of interest reported by authors.- Published
- 2024
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