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Copyright of Journal of the Child / Çocuk Dergisi is the property of Journal of Child and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Current Pediatrics / Guncel Pediatri is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Leukemia inhibitory factor (LIF) is the most pleiotropic member of the interleukin-6 family of cytokines. It utilises a receptor that consists of the LIF receptor ß and gp130 and this receptor complex is also used by ciliary neurotrophic growth factor (CNTF), oncostatin M, cardiotrophin1 (CT1) and cardiotrophin-like cytokine (CLC). Evidence is emerging that LIF may play an important role in airway inflammation. Recurrent wheezing is one of the commonest problems of early childhood and respiratory syncytial virus (RSV) is the most frequent cause of wheezy episodes. Material and Method: The aim of this study was to determine whether LIF has a role in the airway inflammation of wheezy children and its relationship with RSV infection. Results: Serum LIF levels, total IgE levels, RSV-IgM and RSVIgG antibodies were evaluated in wheezy (22F, 18M) and healthy (18F, 20M) infants. RSV-IgM antibodies were detected in 25% of wheezy and 3% of healthy children. RSV-IgG antibodies were detected 35% and 23%, respectively. There was not significant difference in median serum levels of LIF between wheezy and healthy infants. However, median serum LIF level of subjects who were seropositive for RSV-IgM antibodies was significantly higher than those who were seronegative for RSV-IgM antibodies (16 pg/ml vs 10.5 pg/ml; p=0.01). Conclusion: This study suggests that LIF might play a role in early airway inflammation in infants with wheezy RSV infection. [ABSTRACT FROM AUTHOR]

Mastocytosis is a heterogeneous disorder characterized by clonal proliferation and accumulation of mast cells in one of more organs which may lead to different clinical pictures. Pathological increase and activation of mast cells in various tissues can cause different clinical pictures. Cutaneous mastocytosis limited to the skin is the most typical clinical picture observed in children and systemic mastocytosis is very rare in the pediatric age group. The diagnosis of cutaneous mastocytosis is based on clinical findings, but is often delayed due to lack of clinical awareness of the disease and lack of its consideration in the differential diagnosis. This article focuses on the current diagnosis, management and treatment of cutaneous mastocytosis in children in order to increase awareness about this issue. [ABSTRACT FROM AUTHOR]

Asthma is the most frequently seen chronic disease in childhood. With our current treatment options asthma is not a curable disease, so it is not inevitable for asthma patients to seek medical care for exacerbations. Asthmatic exacerbation is a major cause for patients to visit emergency services and may even cause hospitalization. Increased treatment-cost, anxiety among parents and missed school days for children are other adverse events that are caused by asthma exacerbations. Quick anamnesis, physical examination and evaluation of frequency of exacerbations followed by early initiation of the therapy, is the simple algorithm for approaching asthma exacerbations. Children who are older than 5 years differ both anatomically and physiologically from younger ones, so the procedures which should be performed during both the treatment of asthma, and demonstrate differences this changes controlling-therapy as well as exacerbation-therapy approach for these patients. While determining the treatment plan patient's age should be taken into consideration. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi is the property of Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Dry powder inhalers (DPIs) are used in children with increased frequency, since no coordination between actuation and inhalation is required and the devices can easily be carried around. Material and Methods: The aim of this study was to measure the peak inspiratory flow (PIF) in 20 asthmatic (5F, I5M) and 39 (15 F. 24 M) healthy school children aged 6 to 8 years, and to evaluate the applicability of DPI in this age group. Children with mild to moderate asthma were included in the study. PIF was performed by means of In-Check Dial (Clement Clarke International, UK). Pulmonary function tests including FEVl and PEF were performed. Results: For the asthmatic group median FEVl, PEF and PIF and related percentages were 91.6 (28.5%), 82.4 (21.1%) and 78.8 26.4 Umin, respectively. For the healthy controls, the respective measurements were 89.5 (14.7%), 81.7 (16.0%) and 81.2 20.2 Umin. Ranges for the asthmatics were 40 Umin to 120 Umin. and 45 to 120 for the healthy controls A positive correlation between PIF and FEVl (p<0.00l, r=0.492) was observed in both groups. Conclusion: Since a PIF of at least 15 Umin is required for the use of most DP! devices, we concluded that children aged 6 years or more with mild to moderate asthma can use DPIs with efficacy and ease. Furthermore, because of the correlation between PIF and PEF, it may be useful to measure PIF during an asthma attack with relatively low PEF, before prescribing a DP! device. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the Child / Çocuk Dergisi is the property of Journal of Child and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Türk Pediatri Arşivi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Child / Çocuk Dergisi is the property of Journal of Child and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asthma Allergy Immunology / Astim Allerji Immunoloji is the property of Turkish National Society of Allergy & Clinical Immunology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Hereditary angioedema (HA) is a rare, autosomal-dominant genetic disorder presenting with recurrent attacks of angioedema. The most commonly involved organs include the extremites, face, neck, upper respiratory tract, genital region and the gastrointestinal tract. Edema of the intestinal mucosa can cause temporary obstruction and severe abdominal pain that can be confused with acute abdomen. Pediatricians and emergency physicians should keep in mind this rare disease in the differential diagnosis of severe abdominal pain. [ABSTRACT FROM AUTHOR]