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Start Over Author "Fsadni D" Topic chlamydia infections
3 results on '"Fsadni D"'

2. Comparison of an enzyme immunoassay (IDEIA) with tissue culture isolation for detection of Chlamydia trachomatis using a single swab.

Author

Krech T, Gerhard-Fsadni D, Degen KW, Vossel R, and Géraud GP

Subjects
Animals, Cell Line, Culture Media, Female, Fluorescent Antibody Technique, Humans, Male, Predictive Value of Tests, Specimen Handling, Time Factors, Chlamydia Infections diagnosis, Chlamydia trachomatis isolation & purification, Immunoenzyme Techniques, Sexually Transmitted Diseases diagnosis
Abstract

We directly compared a monoclonal antibody-based enzyme immunoassay (IDEIA) with isolation of Chlamydia trachomatis in cell culture (Buffalo Green Monkey cells) by changing the transport medium used for the IDEIA test so as to allow use of a single swab for both tests of the two techniques. We also modified the IDEIA test to exclude any possibility of false positive results caused by non-specific interference by Staphylococcus aureus. The observed sensitivity of the IDEIA compared to cell culture was rather low, 80.3% (57/71). However the IDEIA test's specificity was excellent, 99.7% (566/564) giving a positive predictive value of 96.6% and a negative predictive value of 97.9% (isolation rate by cell culture = 11%).

Published
1989

3. [Significance and problems of Chlamydia detection in urologic patients].

Author

Krech T, Gerhard-Fsadni D, Miller SM, and Hofmann N

Subjects
Antibodies, Monoclonal, Bacteriological Techniques, Chlamydia trachomatis immunology, Epididymitis diagnosis, Female, Fluorescent Antibody Technique, Humans, Immunoenzyme Techniques, Infertility, Male diagnosis, Male, Prostatitis diagnosis, Uterine Cervicitis diagnosis, Chlamydia Infections diagnosis, Sexually Transmitted Diseases diagnosis, Urethritis diagnosis
Abstract

Chlamydiae represent the aetiological agent in non-gonococcal urethritis in about 50% of the cases, but it is also increasingly recognized that Chlamydia trachomatis can cause prostatitis or epididymitis. The introduction of methods for the direct detection of chlamydia in clinical materials allows early diagnosis and therefore effective antibiotic therapy. The new tests however give both false positive and false negative results.

Published
1986

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