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Objective To assess family environmental factors that impact caries in children during a follow ⁃ up study for family⁃based community oral health promotion models. Methods This study was conducted from June to De⁃ cember 2015. A total of 200 households were selected from Jinzhou community in Nanning with the random sampling method. The data were collected through oral examinations and questionnaire surveys of family members. A logistic re⁃ gression model was used to analyze the relationship between family environment factors, such as socioeconomic and fam⁃ ily⁃related behaviors, and caries in children. Results After adjustment for confounding factors, families in which more than 1, 000 mL of sugar drinks were purchased per month; those in which the family members had a low frequency of brushing (occasionally or not); those in which the mother had a high frequency of drinking sweet drinks (more than one time each day), brushed with low frequency (less than 2 times), had no regular oral examination in the past year, or had low scores in oral health attitude and knowledge; those in which the father/mother had a low level of education (short⁃cy⁃ cle courses and under); and those with a low annual household income (less than 50, 000 RMB) had children with high rates of dental caries. Families purchasing sugar drinks >1 000 mL per month were 2.22 times more likely than families purchasing sugar drinks ≤1 000 mL per month to have caries in children. Conclusion Family environmental factors exert a certain influence on children􀆳s caries, and this information is a useful reference for a follow⁃up study.

Objectives: The objectives of this study were to evaluate the cost-effectiveness and cost-benefit of fluoride varnish (FV) interventions for preventing caries in the first permanent molars (FPMs) among children in rural areas in Guangxi, China. Methods: This study constituted a secondary analysis of data from a randomised controlled trial, analysed from a social perspective. A total of 1,335 children aged 6–8 years in remote rural areas of Guangxi were enrolled in this three-year follow-up controlled study. Children in the experimental group (EG) and the control group (CG) received oral health education and were provided with a toothbrush and toothpaste once every six months. Additionally, FV was applied in the EG. A decision tree model was developed, and single-factor and probabilistic sensitivity analyses were conducted. Results: After three years of intervention, the prevalence of caries in the EG was 50.85%, with an average decayed, missing, and filled teeth (DMFT) index score of 1.12, and that in the CG was 59.04%, with a DMFT index score of 1.36. The total cost of caries intervention and postcaries treatment was 42,719.55 USD for the EG and 46,622.13 USD for the CG. The incremental cost-effectiveness ratio (ICER) of the EG was 25.36 USD per caries prevented, and the cost–benefit ratio (CBR) was 1.74 USD benefits per 1 USD cost. The results of the sensitivity analyses showed that the increase in the average DMFT index score was the largest variable affecting the ICER and CBR. Conclusions: Compared to oral health education alone, a comprehensive intervention combining FV application with oral health education is more cost-effective and beneficial for preventing caries in the FPMs of children living in economically disadvantaged rural areas. These findings could provide a basis for policy-making and clinical choices to improve children's oral health. [ABSTRACT FROM AUTHOR]