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4 results on '"Roma, E."'

1. Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe

Author

de Bie, C.I., Buderus, S., Sandhu, B.K., de Ridder, L., Paerregaard, A., Veres, G., Dias, J.A., Escher, J.C., Amil Dias, J., Trindade, E., Bochenek, K., Lazowska, I., Bujanover, Y., Chong, S.K., Cucchiara, S., Fell, J.M., Henker, J., Hugot, J.P., Sladek, M., Kolaček, Sanja, Koletzko, S., Levine, A., Lionetti, P., Maly, J., Murphy, M.S., Spray, C., Finkel, Y., Holmquist, L.M., Ruemmele, F., Staiano, A., Malmborg, P., Hildebrand, H., Veereman, G., Eglite, L., Keller, K, Hradsky, O., Nevoral, J., Bronsky, J., Orel, R., Ravelli, A., Roma, E., Socha, P., Størdal, K., Perminow, G., van Biervliet, S., and Pediatrics

Subjects
Male, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Adolescent, medicine.medical_treatment, Population, Colonoscopy, Gastroenterology, Inflammatory bowel disease, Endoscopy, Gastrointestinal, Crohn Disease, Internal medicine, Intestine, Small, medicine, Humans, Intubation, Registries, Child, education, Intubation, Gastrointestinal, Pediatric gastroenterology, Internet, Medical Audit, education.field_of_study, medicine.diagnostic_test, business.industry, Incidence, Infant, Newborn, Infant, Magnetic resonance imaging, IBD, children, Hepatology, Inflammatory Bowel Diseases, medicine.disease, Quality Improvement, Ulcerative colitis, digestive system diseases, Europe, Child, Preschool, Practice Guidelines as Topic, Pediatrics, Perinatology and Child Health, Colitis, Ulcerative, Female, business
Abstract

OBJECTIVE In 2005, the Inflammatory Bowel Disease (IBD) Working Group of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition published consensus guidelines on the diagnostic workup of paediatric IBD, the Porto criteria. According to these guidelines, children suspected of having IBD should undergo an oesophagogastroduodenoscopy (OGD), ileocolonoscopy, and (except in cases of definitive ulcerative colitis) adequate imaging of the small bowel. To audit and evaluate the diagnostic workup of paediatric patients with IBD in Europe, the Working Group created EUROKIDS, a prospective, Web-based registry of newly diagnosed paediatric patients with IBD. METHODS Patients with IBD (ages 0-18 years) were registered in 44 centres in 18 countries. Data on diagnostic workup were analysed according to the year of diagnosis, type of IBD, and centre size. Diagnostic yield of OGD and ileal intubation were evaluated. RESULTS Between 2004 and 2009, 2087 newly diagnosed patients were correctly registered. Both OGD and ileocolonoscopy had been performed in 64% of all of the patients and increased significantly from year 1 (52 %) to 5 (71%, P

Published
2012

2. Retinol Binding Protein 4 in children with Inflammatory Bowel Disease: a negative correlation with the disease activity.

Author

Roma, E., Krini, M., Hantzi, E., Sakka, S., Panayiotou, I., Margeli, A., Papassotiriou, I., and Kanaka-Gantenbein, C.

Subjects
*PROTEIN research, *PEDIATRIC research, *INFLAMMATORY bowel diseases, *ETIOLOGY of diseases, *BODY mass index, *CROHN'S disease, *BLOOD sedimentation, *TRANSTHYRETIN
Abstract

Objectives: Retinol Binding Protein-4 (RBP-4), the action of which was initially thought to be only the transport of vitamin A, is a major circulating adipocytokine involved in the inflammation. We evaluated the serum RBP-4 levels in children with inflammatory bowel disease (IBD) and correlated them with transthyretin (TTR), inflammation markers, disease activity, and body mass index (BMI). Design: In 41 children of mean age 11.9 ± 3.6 years (range 5-17.7 y) with IBD (19 with Crohn's disease (CD) and 22 with Ulcerative colitis (UC) serum RBP-4, TTR, Amyloid A (SAA), C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR), disease activity and BMI were prospectively determined and compared with those of 42 matched controls. Results: No difference in the RBP-4 and TTR serum levels, between patients and controls as well as between active and remission state of the disease was noticed. A negative correlation of serum RBP-4 with the disease activity, SAA and ESR and a positive correlation with TTR was found, but no significant correlation with CRP or BMI was found. Inflammation markers were significantly increased in patients compared to controls and had a positive correlation with the disease activity. Conclusions: RBP-4 negatively correlated with disease activity of children with IBD probably indicating a protective anti-inflammatory mechanism of action in addition to transport of vitamin A. [ABSTRACT FROM AUTHOR]

Published
2012

3. Dietary compliance and life style of children with coeliac disease.

Author

Roma, E., Roubani, A., Kolia, E., Panayiotou, J., Zellos, A., and Syriopoulou, V. P.

Subjects
*GLUTEN-free diet, *CELIAC disease, *DIET in disease, *DIET therapy, *INTERNAL medicine, *CHILDREN'S health, *LIFESTYLES, *HUMAN behavior, *QUALITY of life
Abstract

Background: Coeliac disease (CD) is common and requires a permanent strict gluten-free diet (GFD). However, data concerning how the situation is experienced by children are limited. The present study aimed to investigate the compliance with a GFD and the impact of CD and GFD on the lifestyle of patients and their families, together with proposed recommendations for improvement of quality of life. Methods: Children with biopsy confirmed CD were recruited consecutively from the outpatient gastroenterology clinic. Participants were evaluated by a special questionnaire for compliance with the GFD, patients’ knowledge about CD, and the well-being and lifestyle of children and their families. Comparisons between discrete variables were performed by a chi-square test. Results: Seventy-three children of median age 9.4 (interquartile range = 5–14.5) years were evaluated. Compliance to diet was reported by 58%. Reasons for noncompliance were: poor palatability (32%), dining outside home (17%), poor availability of products (11%), and asymptomatic disease diagnosed by screening (11%). The acceptance of the GFD was reported as good in 65%, whereas avoidance of travelling and restaurants was stated by 17% and 46% of families, respectively. Most families experienced difficulties detecting gluten from the food label. Proposed factors for improvement of quality of life were: better labelling of gluten-containing ingredients (76%) and more gluten-free (GF) foods in supermarkets (58%) and restaurants (42%). Conclusions: Children with CD have low compliance with the GFD. Better education about the disease, the availability of GF products, and appropriate food labelling could improve compliance and quality of life. [ABSTRACT FROM AUTHOR]

Published
2010
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4. Differences in Management of Eosinophilic Esophagitis in Europe: An Assessment of Current Practice

Author

Eleftheria Roma, Gilles Tourlamain, Noam Zevit, Jorge Amil Dias, Christiane Sokollik, Roger Garcia-Puig, Carolina Gutiérrez-Junquera, Johanna H. Oudshoorn, Caterina Strisciuglio, Kasia Karolewska-Bochenek, Marcus Karl-Heinz Auth, Orel Rok, Mike Thomson, Saskia Vande Velde, Salvatore Oliva, Aco Kostovski, Christos Tzivinikos, Alexandra Papadopoulou, Nicolas Kalach, Vaidotas Urbonas, O. Bauraind, Sebastian Otte, Tourlamain, G., Garcia-Puig, R., Gutierrez-Junquera, C., Papadopoulou, A., Roma, E., Kalach, N., Oudshoorn, J., Sokollik, C., Karolewska-Bochenek, K., Oliva, S., Strisciuglio, C., Bauraind, O., Auth, M. K. -H., Thomson, M., Otte, S., Rok, O., Dias, J. A., Tzivinikos, C., Urbonas, V., Kostovski, A., Zevit, N., and Velde, S. V.

Subjects
esophagitis, diagnosis, CHILDREN, GUIDELINES, Pediatrics, 0302 clinical medicine, Medicine and Health Sciences, Medicine, Child, medicine.diagnostic_test, treatment, adult, pediatric, Gastroenterology, Perinatology, Clinical Practice, and Child Health, Europe, diagnosi, VARIABILITY, Current practice, General practice, 030211 gastroenterology & hepatology, France, Esophageal dysfunction, Adult, medicine.medical_specialty, GASTROENTEROLOGISTS, CONSENSUS RECOMMENDATIONS, 03 medical and health sciences, 030225 pediatrics, Internal medicine, Biopsy, EOE, Humans, In patient, Eosinophilic esophagitis, Portugal, business.industry, esophagiti, Proton Pump Inhibitors, ADULTS, Eosinophilic Esophagitis, medicine.disease, United Kingdom, Spain, Pediatrics, Perinatology and Child Health, Poland, business, Esophagitis
Abstract

OBJECTIVES The aim of the study was to assess differences in the diagnosis and management of eosinophilic esophagitis (EoE) by European pediatric (PG) and adult gastroenterologists (AG), and their self-reported adherence to guidelines. METHODS A multiple-choice questionnaire gauged the diagnostic and management strategies of gastroenterologists treating children or adults in 14 European countries and the United Arab Emirates (UAE). RESULTS Questionnaires were completed by 465 PG and 743 AG. PG were significantly more likely to take biopsies in patients with symptoms of esophageal dysfunction (86.2% PG vs 75.4% AG, P

Published
2020

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