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Your search keyword '"D'Ottavio P"' showing total 9 results
Start Over Author "D'Ottavio P" Topic children
9 results on '"D'Ottavio P"'

1. Use of music therapy in pediatric oncology: an Italian AIEOP multicentric survey study in the era of COVID-19

Author

Giordano, Filippo, Muggeo, Paola, Rutigliano, Chiara, Barzaghi, Federica, Battisti, Laura, Coccia, Paola, Colombini, Antonella, D’Amico, Maria Rosaria, De Santis, Raffaella, Mascarin, Maurizio, Mura, Rossella, Onofrillo, Daniela, Perruccio, Katia, Rinieri, Simona, Trevisan, Francesca, Zama, Daniele, Ziino, Ottavio, De Lucia, Marica, Santoro, Nicola, and Cesaro, Simone

Published
2023
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2. Favorable outcome of SARS-CoV-2 infection in pediatric hematology oncology patients during the second and third pandemic waves in Italy: a multicenter analysis from the Infectious Diseases Working Group of the Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP)

Author

Zama, Daniele, Baccelli, Francesco, Colombini, Antonella, Contino, Amalia, Calore, Elisabetta, Petris, Maria Grazia, Meneghello, Linda, Mercolini, Federico, Lo Vecchio, Andrea, Montalto, Shana, Meazza, Cristina, Barone, Angelica, Compagno, Francesca, Muggeo, Paola, Soncini, Elena, Brescia, Letizia, Giraldi, Eugenia, Giurici, Nagua, Mura, Rosa Maria, Cellini, Monica, Perruccio, Katia, Petroni, Valeria, La Spina, Milena, Ziino, Ottavio, Burnelli, Roberta, De Santis, Raffaella, Mascarin, Maurizio, Barretta, Valentina, Tridello, Gloria, and Cesaro, Simone

Published
2022
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8. Altered expression of innate immunity genes in different intestinal sites of children with ulcerative colitis.

Author

Stronati, Laura, Negroni, Anna, Pierdomenico, Maria, D’Ottavio, Chiara, Tirindelli, Donatella, Di Nardo, Giovanni, Oliva, Salvatore, Viola, Franca, and Cucchiara, Salvatore

Subjects
NATURAL immunity, GENE expression, ULCERATIVE colitis in children, INFLAMMATION, INTESTINAL mucosa, MESSENGER RNA, ILEUM diseases, ULCERATIVE colitis diagnosis, THERAPEUTICS
Abstract

Abstract: Background: Innate immunity has been very rarely investigated in ulcerative colitis and never in paediatrics. The present study was aimed at describing expression of innate immunity genes (NOD2, RIP2, α-defensins HD5 and HD6) in inflamed colon and in ileum of children with ulcerative colitis. Expression of TNFα and IL-1β was also analyzed. Methods: 15 children with ulcerative colitis (9 pancolitis, 6 left-sided colitis) and 10 control children were enrolled. mRNA and protein expressions were detected by real time PCR and western blot assays. Results: NOD2, RIP2, IL-1β, TNFα expression levels were significantly increased in colonic mucosa of patients compared to controls (p <0.01). These genes were also upregulated (p <0.01) in the ileum of both pancolitis and left-sided colitis children. HD5 and HD6 were significantly upregulated (p <0.01) in the inflamed colon of patients as well as in the ileum of those with pancolitis. Conclusions: An increased mucosal expression of innate immunity genes was found in the inflamed colon of children with ulcerative colitis, outlining the role of the innate immune response in disease pathogenesis. Involvement of the ileum in ulcerative colitis suggests that an immune activation can also be established in intestinal sites classically uninvolved by the inflammation, carrying implications for the treatment and course of the disease. [ABSTRACT FROM AUTHOR]

Published
2010
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9. Lipoblastoma in infant: Our experience.

Author

Armenise, Tommaso, Gentile, Ottavio, Orofino, Antonio, Leggio, Samuele, Lanzillotto, Maria Paola, Zullino, Francesca, and Paradies, Guglielmo

Subjects
DIAGNOSIS of tumors in children, INFANT disease treatment, CANCER relapse, TUMOR surgery, DIAGNOSIS, LIPOSARCOMA, THERAPEUTICS
Abstract

Lipoblastoma is a rare benign soft tissue tumor that occurs most commonly in infants and children. The wide majority are detected in children under the age of 3 years. Lipoblastoma usually present as a rapidly growing mass most often located in the trunk and extremities. Lipoblastoma has rarely been reported in the inguino-labial region. No malignant degeneration has been documented while a high recurrence rate has been described and is usually correlated to the diffuse-type lesions (lipoblastomatosis) and to incomplete excision. [ABSTRACT FROM AUTHOR]

Published
2015
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