1. A ternary heterostructure aptasensor based on metal-organic framework and polydopamine nanoparticles for fluorescent detection of sulfamethazine.
- Author
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Liang N, Shi B, Hu X, Li W, Huang X, Li Z, Zhang X, Zou X, and Shi J
- Subjects
- Animals, Swine, Biosensing Techniques instrumentation, Fluorescence, Spectrometry, Fluorescence, Metal-Organic Frameworks chemistry, Indoles chemistry, Sulfamethazine analysis, Sulfamethazine chemistry, Polymers chemistry, Nanoparticles chemistry, Chickens, Food Contamination analysis, Aptamers, Nucleotide chemistry
- Abstract
Residue of sulfamethazine (SMZ), a typical short-acting drug to prevent bacterial infections, in food is a threat to human health. A ternary heterogeneous metal-organic framework hybrid (Zn/Fe-MOF@PDANSs) of Zn-TCPP-MOF, MIL-101 (Fe) and polydopamine nanoparticles (PDANSs) was proposed to establish an aptasensor for the sensitive and selective detection of SMZ. In this sensor, Zn-TCPP-MOF and FAM emitted fluorescence at 609 nm and 523 nm, respectively, and the fluorescence of FAM-ssDNA could be quenched when it was adsorbed on the surface of MOF hybrid. In the presence of SMZ, the fluorescence of FAM-ssDNA recovered due to the dropping from MOF hybrid, while the fluorescence of MOF hybrid remained. With this strategy, a wide concentration range and high sensitivity of SMZ were detection. And the ternary Zn/Fe-MOF@PDANSs sensor exhibited more excellent performance than binary Zn/Fe-MOF aptasensor. In addition, the sensor showed pleasurable selectivity, and was utilized for SMZ determination in authentic chicken and pork samples, implying the fascinating potential in practical application., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)
- Published
- 2024
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