1. A differentially selective probe for trivalent chemosensor upon single excitation with cell imaging application: potential applications in combinatorial logic circuit and memory devices.
- Author
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Das, Dipankar, Alam, Rabiul, Katarkar, Atul, and Ali, Mahammad
- Subjects
CHEMORECEPTORS ,CELL imaging ,RHODAMINES ,HYDROCARBONS ,BENZYLAMINE - Abstract
A new rhodamine 6G-benzylamine-based sensor (L
1 ), having only hydrocarbon skeletons in the extended part, was synthesized and characterized by single-crystal X-ray crystallographic study. It exhibited excellent selective and sensitive recognition of trivalent metal ions M3+ (M = Fe, Al and Cr) over mono- and di-valent and other trivalent metal ions. A large enhancement of the fluorescence intensity for Fe3+ (41-fold), Al3+ (31-fold) and Cr3+ (26-fold) was observed upon the addition of 3.0 equivalent of these metal ions into the probe in H2 O/CH3 CN (4 : 1, v/v, pH 7.2) with naked eye detection. The corresponding Kf values were evaluated to be 9.4 × 103 M−1 (Fe3+ ), 1.34 × 104 M−1 (Al3+ ) and 8.7 × 103 M−1 (Cr3+ ). Quantum yields of the L1 , [L1 –Fe3+ ], [L1 –Al3+ ] and [L1 –Cr3+ ] complexes in H2 O/CH3 CN (4 : 1, v/v, pH 7.2) were found to be 0.012, 0.489, 0.376 and 0.310, respectively, using rhodamine-6G as standard. LODs for Fe3+ , Al3+ and Cr3+ were determined by 3σ methods and found to be 1.28, 1.34 and 2.28 μM, respectively. Cyanide ion scavenged Fe3+ from the [Fe3+ –L1 ] complex and quenched its fluorescence via its ring-closed spirolactam form. Advanced level molecular logic devices using different inputs (2 and 4 inputs) as advanced level logic gates and memory devices were constructed. The large enhancement in fluorescence emission of L1 upon complexation with M3+ metal ions makes the probe suitable for the bio-imaging of M3+ (M = Fe, Al and Cr) in living cells. [ABSTRACT FROM AUTHOR]- Published
- 2019
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