1. Prognostic significance of nodular number in patients undergoing hepatectomy of intermediate-stage hepatocellular carcinoma.
- Author
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Fan, Zhong-Qi, Serenari, Matteo, Lv, Xing, Schwartz, Myron, Qiu, Wei, Pawlik, Timothy M, Chen, Zhong, Zhou, Ya-Hao, Wang, Xian-Ming, Chen, Ting-Hao, Li, Jie, Zhang, Cheng-Wu, Wang, Hong, Zhang, Yao-Ming, Gu, Wei-Min, Liang, Ying-Jian, Diao, Yong-Kang, Yao, Lan-Qing, Li, Chao, and Cescon, Matteo
- Subjects
HEPATOCELLULAR carcinoma ,CHEMOEMBOLIZATION ,HEPATECTOMY ,SURGICAL blood loss ,PATIENT selection ,SURGERY - Abstract
This article, published in the British Journal of Surgery, examines the importance of nodular number in predicting the prognosis of patients with intermediate-stage hepatocellular carcinoma (HCC) who undergo hepatectomy. The study, conducted at multiple hepatobiliary centers in China, Italy, and the USA, analyzed data from HCC patients who had undergone curative-intent hepatic resection between 2008 and 2018. The findings indicate that patients with three or more tumor nodules had lower overall survival and recurrence-free survival rates compared to those with two nodules. The study suggests that nodular number should be considered when predicting long-term prognosis after hepatic resection for intermediate-stage HCC. However, further research is needed to validate these findings. The study was supported by various funding sources and the authors have no conflicts of interest. [Extracted from the article]
- Published
- 2024
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