Author: "M von Strandtmann" / Topic: chemistry.chemical_compound - Searchworks@Jio Institute Digital Library Search Results

Author: Marvin P. Cohen, Sylvester Klutchko, M. Von Strandtmann, and J. Shavel
Subjects: chemistry.chemical_compound, chemistry, Organic Chemistry, Organic chemistry, Hydroxymethyl
Abstract: A novel synthesis of 3-(hydroxymethyl)chromones from o-hydroxy-ω-(methylsulfinyl)acetophenones has been developed. These have been utilized in the synthesis of 3-formyl, 3-cyano, 3-carboxy, 3-carboxamido, 3-chloromethyl, 3-aminomethyl and 3-methoxymethylchromones.
Published: 1974
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Author: M von Strandtmann and David T. Connor
Subjects: Antifungal Agents, Ketone, Stereochemistry, Alcohol, medicine.disease_cause, Aldehyde, Structure-Activity Relationship, chemistry.chemical_compound, fluids and secretions, Oximes, Drug Discovery, medicine, Structure–activity relationship, Myxococcales, Candida albicans, Pyrans, chemistry.chemical_classification, Aldehydes, Bacteria, biology, Fungi, Chemical modification, Ketones, bacterial infections and mycoses, biology.organism_classification, Oxime, chemistry, Alcohols, Streptococcus pyogenes, Molecular Medicine
Abstract: Alcohol, ketone, aldehyde, and oxime analogues of ambruticin (1) were prepared. The analogues were tested against Histoplasma capsulatum, Microsporum fulvum, Candida albicans, and Streptococcus pyogenes. Structure-activity relationships are described. Increasing the bulk of substituent at C1 and C5 reduces antifungal activity.
Published: 1979
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Author: David T. Connor and M. Von Strandtmann
Subjects: chemistry.chemical_compound, chemistry, Stereochemistry, Organic Chemistry, Benzofuran, Ring (chemistry)
Published: 1973
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Author: Marvin P. Cohen, M. Von Strandtmann, and J. Shavel
Subjects: chemistry.chemical_compound, chemistry, Pyran, Organic Chemistry, Drug Discovery, Reinforced carbon–carbon, Organic chemistry, Alkylation, Ring (chemistry), Biochemistry
Published: 1965
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Author: J. Shavel, M. Von Strandtmann, Sylvester Klutchko, and A. C. Sonntag
Subjects: chemistry.chemical_compound, Chemistry, Organic Chemistry, Pyrroline, Medicinal chemistry
Published: 1973
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Author: M. Von Strandtmann, A. C. Sonntag, J. Shavel, and Sylvester Klutchko
Subjects: chemistry.chemical_compound, Chemistry, Kornblum–DeLaMare rearrangement, Organic Chemistry, Pyrroline, Sigmatropic reaction, Omega, Medicinal chemistry, Carroll rearrangement
Published: 1973
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Author: David T. Connor and M. Von Strandtmann
Subjects: Polyangium, Antifungal, chemistry.chemical_compound, chemistry, medicine.drug_class, Stereochemistry, Amide, Antibiotics, medicine, Chemical modification, General Medicine, AMBRUTICIN
Published: 1980
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Author: M. Von Strandtmann and David T. Connor
Subjects: chemistry.chemical_classification, Polyangium, Antifungal, Ketone, Stereochemistry, medicine.drug_class, Antibiotics, Chemical modification, Alcohol, General Medicine, Oxime, Aldehyde, chemistry.chemical_compound, chemistry, medicine, Organic chemistry
Abstract: Ambruticin (I) wird auf den im Formelschema skizzierten Wegen in Analoga (II)-(XII) umgewandelt.
Published: 1980
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Author: Marvin P. Cohen, Sylvester Klutchko, J. Shavel, and M. Von Strandtmann
Subjects: chemistry.chemical_classification, chemistry.chemical_compound, Chemistry, Organic Chemistry, Organic chemistry, Flavones, Thioindigo
Published: 1972
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