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Bicyclic structures were synthesized by LACASA-DA cycloaddition reaction using (S)-BINOL as a chiral inductor. The N-2 pyridazine position was protected; the hydroxyl group was carbonylated to form...

Comparing energy metabolism in human skeletal muscle and primary skeletal muscle cells in obesity, while focusing on glucose and fatty acid metabolism, shows many common changes. Insulin-mediated glucose uptake in skeletal muscle and primary myotubes is decreased by obesity, whereas differences in basal glucose metabolism are inconsistent among studies. With respect to fatty acid metabolism, there is an increased uptake and storage of fatty acids and a reduced complete lipolysis, suggesting alterations in lipid turnover. In addition, fatty acid oxidation is decreased, probably at the level of complete oxidation, as β -oxidation may be enhanced in obesity, which indicates mitochondrial dysfunction. Metabolic changes in skeletal muscle with obesity promote metabolic inflexibility, ectopic lipid accumulation, and formation of toxic lipid intermediates. Skeletal muscle also acts as an endocrine organ, secreting myokines that participate in interorgan cross talk. This review highlights interventions and some possible targets for treatment through action on skeletal muscle energy metabolism. Effects of exercise in vivo on obesity have been compared with simulation of endurance exercise in vitro on myotubes (electrical pulse stimulation). Possible pharmaceutical targets, including signaling pathways and drug candidates that could modify lipid storage and turnover or increase mitochondrial function or cellular energy expenditure through adaptive thermogenic mechanisms, are discussed.

To find novel classes of potential fuel additives of multivalent activity, particularly antioxidants, a series of recently synthesized ethyl-6-amino-5-cyan-methyl-4-aryl-4H-pyran-3-carboxylates have been investigated using model oxidative reactions. The compounds studied appear to be prospective inhibitors of hydrocarbons oxidation. Some of them are antioxidants of combined action, breaking the chains of the oxidative reactions with cumene peroxide radicals and catalytically decomposing cumene hydroperoxide.

In the cation of the title salt, C17H18N3S+·Br−·C3H7NO, the central thiazolidine ring adopts an envelope conformation with puckering parameters Q(2) = 0.310 (3) Å and φ(2) = 42.2 (6)°. In the crystal, each cation is connected to two anions by N—H... Br hydrogen bonds, forming an R 4 2(8) motif parallel to the (10\overline{1}) plane. van der Waals interactions between the cations, anions and N,N-dimethylformamide molecules further stabilize the crystal structure in three dimensions. The most important contributions to the surface contacts are from H...H (55.6%), C...H/H...C (17.9%) and Br...H/H...Br (7.0%) interactions, as concluded from a Hirshfeld analysis.

In the crystal of the title compound, C7H5FN4S, the molecules are non-planar, with dihedral angle formed by least-squares planes of tetrazole and benzene rings of 59.94 (8) °. The crystal packing is formed by N—H...S hydrogen bonds, which link the molecules into centrosymmetric dimers with an R 2 2(8) ring motif, and by the offset face-to-face π–π stacking interactions between the benzene rings, which join the dimers into layers parallel to (100). The Hirshfeld surface analysis shows that the most important contributions to the surface contacts are from N...H/H...N (21.9%), S...H/H...S (21.1%), H...H (14.6%), F...H/H...F (11.8%) and C...H/H...C (9.5%) interactions.

3-Amino-5-phenyl-1,3-thiazolidin-2-iminium bromide was synthesized for the first time by reaction of (1,2-dibromoethyl)benzene with thiosemicarbazide hydrochloride. Its condensation with aromatic aldehydes afforded the corresponding Schiff bases. The structure of the isolated compounds was confirmed by 1H and 13C NMR spectroscopy.

The central thiazolidine ring of the title salt, C16H16N3S+center dot Br-, adopts an envelope conformation, with the C atom bearing the phenyl ring as the flap atom. In the crystal, the cations and anions are linked by N-H center dot center dot center dot Br hydrogen bonds, forming chains parallel to the b-axis direction. Hirshfeld surface analysis and two-dimensional fingerprint plots indicate that the most important contributions to the crystal packing are from H center dot center dot center dot H (46.4%), C center dot center dot center dot H/H center dot center dot center dot C (18.6%) and H center dot center dot center dot Br/Br center dot center dot center dot H (17.5%) interactions.

The reaction of 5-acetyl-4-aryl-6-hydroxy-3,6-dimethyl-4,5,6,7-tetrahydroindazoles p-toluenesulfonyl chloride in boiling acetone in the presence of triethylamine was found to occur in a completely regioselective with the exclusive formation of 5-acetyl-4-aryl-6-hydroxy-3,6-dimethyl-1-(4-methylbenzenesulfonyl)-4,5,6,7-tetrahydroindazoles. The experimental results were confirmed by quantum chemical calculations. In silico biological activity evaluation of the synthesized compounds was performed.

Biological active compounds on the basis of 3-amino-5-phenylthiazolidin-2-iminium bromide were synthesized, and their biological activity was studied. The structures of the synthesized compounds were confirmed by 1H and 13C NMR spectroscopy and X-ray diffraction analysis.

The nanostructuring of hydroxyl-substituted diazacrown-ether (DC) by silver nanoparticles was obtained by green synthesis method in order to increase the antibacterial activity of silver nanoparticles. The synthesized DC, nanoparticles, and nanosupramolecular complex (Ag@DC) were studied by TEM, powder-XRD, and NMR, IR, and UV spectroscopy methods. The Ag@DC nanostructures were uniform and their sizes ranged from 8 to 18 nm. IR and UV spectra revealed the noncovalent formation of the nanosupramolecular complex. The antibacterial activities of the prepared active agents were investigated on gram-positive and gram-negative bacteria by twofold microdilution method. Ultrastructural study by TEM was performed on \textit{E. coli} BDU12 after treatment with Ag@DC. The results showed the improvement of the antibacterial action of Ag@DC compared to silver nanoparticles (E. coli BDU12 - 32 times, A. baumannii BDU32 - 16 times, K. pneumoniae BDU44 and P. aeruginosa BDU49 - 4 times, S. aureus BDU23 - 512 times). Chelating by DC significantly improved the antibacterial effects of the silver nanoparticles on gram-positive and gram-negative bacteria due to the ionophoric behavior of the crown ethers.

New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrate-catalyzed reaction of acetoacetanilide with 2-(1-arylethylidene)malononitriles (Knoevenagel condensation products of acetophenones and malononitrile) in aqueous ethanol at room temperature. The product structure was confirmed by NMR spectra and X-ray analysis of 1,6-diamino-4a-methyl-3-oxo-2,8-diphenyl-2,3,4,4a-tetrahydroisoquinoline-5,7-dicarbonitrile.

Three-component condensation of benzylideneacetone, ethyl acetoacetate, and malononitrile in the 1:1:1 molar ratio, respectively, in the presence of equimolar quantities of piperidine and glacial acetic acid is studied. The crystal structure of the reaction product (ethyl-2-dicyanomethylene-4-methyl-6-phenyl-3-cyclohexene-1-carboxylate) determined from XRD data by the method of atom-atom potentials contains energy traps in the form of double planar and double two-sided catchers. The energy traps lead to molecular agglomerates occurring in the crystal in the form of slightly deformed translationally identical hexagonal networks.

Cobalt oxide nanoparticles were synthesized using a facile and convenient sonochemical method, followed by a calcination process. For the synthesis, cobalt nitrate, and sodium borohydride w...

In this paper are described the results of the studies, devoted to the investigations of quaternary salt of 2-allyl-4-isooctyl-6-piperidinomethylphenol as corrosion inhibitor of the non-alloy steel in the system, consisting of 3% water solution of NaCl and hydrocarbons (kerosene) at ratio 9 : 1.

Michael addition of various substituted benzylidene- and thiophen-2-ylmethylidenemalononitriles with acetoacetanilide gave the corresponding 5-acetyl-2-amino-4-aryl(hetaryl)-6-oxo-1-phenyl-1,4,5,6-tetrahydropyridine-3-carbonitriles. Treatment of the latter with ethylenediamine in boiling methanol resulted in their rearrangement with elimination of the acetyl group and formation of 2-anilino-4-aryl(hetaryl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles. The product structure was proved by NMR spectroscopy and X-ray analysis.

As a result of triple condensation of malonodinitrile with benzaldehyde and ethyl 2-chloro-3-oxobutanoate a compound with 3-azabicyclo[3.1.0]hexane framework is formed whose crystal structure is determined by X-ray crystallography. In the crystal structure a layered character of the molecular packing is found. Molecules are linked in the layer by H bonds of N-H…O=C and C-H…O=C types and also a large number of atom-atom contacts whose energy corresponds to potential wells.

A detailed study of the dispersion of magnetite (Fe3O4) nanoparticles in the polypropylene (PP) matrix, the degree of coagulation, and the dependence of magnetic properties of PP + Fe3O4nanocomposites on the size of nanoparticles is reported. The size distribution of nanoparticles in polymer matrix and morphology of the nanocomposites were studied by the means of scanning electron microscope (JEOL JSM-7600 F) and atomic force microscopy (NT-MDT). It was found that when the Fe3O4nanoparticles are introduced into the PP matrix, their coagulation takes place. The increase in the size of the Fe3O4nanoparticles depends on their volume content in the polymer matrix, the viscosity of polymer, mixing time, and so on. The magnetic properties of PP + Fe3O4nanocomposites were experimentally and theoretically studied. It was found that the magnetic hysteresis parameters of the nanocomposites directly depend on the size and concentration of the Fe3O4nanoparticles in the matrix. Theoretical calculations were compared with experimental results obtained from M( H) measurements. Discrepancy between theoretical and experimental magnetic values have been explained.

Five demosponges belonging to the order Axinellida: Axinella corrugata, Dragmacidon alvarezae, Dragmacidon reticulatum, Ptilocaulis walpersi, Myrmekioderma rea and one sponge belonging to the order Scopalinida: Scopalina ruetzleri were analyzed to assess their fatty acid composition in the phospholipid fraction. Additionally, the seasonal and intraspecific variation in fatty acids composition was assessed in M. rea and D. alvarezae. Fatty acid identification was conducted using an HRGC-MS with an ECL value of methyl ester derivatives, and analyzing their mass spectra. To confirm double bound location, N-acylpyrrolidide derivatives were used studying their mass spectra. In total, 83 fatty acids were identified with chain lengths ranging from C14 to C32. Interestingly, brominated fatty acids were identified, previously suggested for sponges. Polybranched fatty acids such as 4,8,12-trimethyltridecanoic acid (4,8,12-TMTD) and 3,7,11,15-tetramethylhexadecanoic (phytanic acid) were found, without a clear distribution pattern. A predominance of iso-acids (i-15:0 and i-17:0) on anteiso acids were observed. Some seasonal variations in fatty acid (FA) compositions for M. rea and D. alvarezae were observed. The hierarchical Clusters Analysis (HCA) showed that the FA composition was species-specific but not informative at the family or order level.

We report an unprecedented multicomponent reaction of acetoacetanilide with malononitrile leading to a structurally novel bicyclic product (9) in a high yield. The structure has been confirmed by X-ray crystallography and comparative Hirshfeld surface analysis of 5-cyano-2-hydroxy-2-methyl-N-phenyl-4-(yridine-4-yl)-6-(thiophen-2-yl)-3,4-dihydro-2H-pyran-3-carboxamide 2, 5-cyano-2-hydroxy-2-methyl-6-oxo-N-phenyl-4-(thiophen-2-yl)piperidine-3-carboxamide 4 and 2-(8-amino-7,8a-dicyano-1-imino-4a-methyl-3-oxo-2-phenyl-1,3,4,4a,5,8a-hexahydroisoquinolin-6(2H)-ylidene)-N-phenylacetamide 9.

Banana passion fruit of the Passiflora genus, are commercially cultivated on a small to medium scale, mainly as edible fruits or as components of traditional herbal medicines. This subgenus comprises several species and hybrid specimens that grow readily in the wild. Due to their taxonomical complexity, many of these species have recently been reclassified (Ocampo Perez and Coppens d’Eeckenbrugge, 2017), and their chemical profile has still to be determined. In this study, an 1H NMR-based platform was applied to the chemical profiling of seven wild species of the Passiflora subgenus, and UHPLC-DAD-MS was additionally used for the identification of phenolic compounds. A total of 59 compounds were detected including 26 O- and C-glycosidated flavonoids and polyphenols, nine organic acids, seven amino acids, GABA, sucrose, glucose, myo-inositol, and five other non-identified compounds. Two of the identified compounds are the previously undescribed C-glycosyl flavonoids, apigenin-4′-O-β-glucopyranosyl, 8-C-β-(6″acetyl)-glucopyranoside and apigenin-4-O-β-glucopyranosyl-8-C-β-neohesperidoside. These C-glycosyl flavonoids were isolated to confirm their proposed structures by NMR and LCMS analysis. The PCA score plots obtained from the 1H NMR data of the studied Passiflora samples showed P. cumbalensis and P. uribei as the species with the most distinguishable chemical profile. In addition, a correlation analysis using OPLS-DA was conducted between 1H-NMR data and the quorum quenching activity (QQ) of Chromobacterium violaceum ATCC 31532. This analysis revealed P. lehmannii, and P. uribei extracts to be the most active, and apigenin-4′-O-β-glucopyranosyl, 8-C-β-(6″acetyl)-glucopyranoside and apigenin-4-O-β-glucopyranosyl-8-C-β-neohesperidoside were identified as possibly responsible for the QQ activity. To confirm this, QQ activity of both compounds was tested against C. violaceum ATCC 3153. An inhibition of violacein production of 0.135 mM (100 μg/mL) and 0.472 mM (300 μg/mL) was observed for apigenin-4′-O-β-glucopyranosyl,8-C-β-(6″acetyl)-glucopyranoside and apigenin-4-O-β-glucopyranosyl-8-C-β-neohesperidoside respectively, while bacterial growth was unaffected in both cases. Furthermore, both compounds showed the ability to inhibit the production of the toxoflavin of the phytopathogen Burkholderia glumae ATCC 33617.

In the present study, we report about the influence of an external permanent magnetic field on electrical resistivity and dielectric permittivity of PP + Fe3O4 and PVDF + Fe3O4 based nanocomposites...

The molecular and crystal structures of 1-(4-fluorophenyl)-1,4-dihydro-1H-tetrazole-5-thione (I) and its complex with cadmium(II) (II) are studied by single crystal XRD. Free ligand I is thione; it has a nonplanar structure (the torsion angle between the tetrazole and benzene rings is 54.99(7)°) and forms H-bonded centrosymmetric dimers via two N–H…S hydrogen bonds in the crystal. The dimers contain a central planar eight-membered {S=C–N–H…S=C–N–H…} ring. Complex II has a chain structure with the composition [(C7H4N4FS)2Cd]n. The environment of the Cd(II) atom consists of two nitrogen atoms and two sulfur atoms from four ligands I and represents a distorted tetrahedron. When complex II forms, ligand I converts into the thiol form. Infinite 1D chains contain eight-membered {←S=C–N–Cd←S=C–N–Cd} rings in a chair conformation. The chains in the crystal are arranged in layers parallel to the (101) plane due to secondary intermolecular F…F and π–π-stacking interactions.

We report a novel three-component condensation of benzalacetophenone, ethyl acetoacetate, and malonodinitrile in a 1:1:1 molar ratio respectively, involving an equimolar amount of morpholine acetate to form ethyl-4,6(R,S)-diphenyl-2-dicyanomethylenecyclohex-3-ene-1(R,S)-carboxylate whose crystal structure is determined by single crystal XRD. The intermolecular interaction is analyzed using an atomatom potential model, and infinite chains of energetically tightly coupled molecules in the crystal structure are identified and described. A weak hydrogen bond of the CAr–H…O type is found.

Schiff base condensation of 2-nitrobenzaldehyde with (para-substituted phenyl)hydrazine in the presence of CH3COONa in EtOH at 80 °C produces (E)-1-(para-substituted phenyl)-2-(2-nitrobenzylidene)hydrazines [−OCH3 (1), −CH3 (2), −H (3), −Br (4), −Cl (5), −F (6)]. CuCl catalyzed olefination of 1−6 with CCl4 in the presence of tetramethylethylenediamine (TMEDA) in DMSO leads to (E)-1-(2,2-dichloro-1-(2-nitrophenyl)vinyl)-2-(para-substituted phenyl)-diazenes [−OCH3 (7), −CH3 (8), −H (9), −Br (10), −Cl (11), −F (12)], respectively. 1–12 were characterized by 1H and 13C NMR spectroscopies, ESI-MS, elemental and X-ray diffraction (for 8, 9 and 12) analysis. The single crystal X-ray analysis of 8, 9 and 12 evidence the intramolecular N⋯Cl pnicogen bonds which is significantly strengthened in view of the planarity of the four atoms involved in the 1,4-membered synthon. The intermolecular halogen and hydrogen bonds also contribute to stabilize the crystal structures of 8, 9 and 12. In DMSO solution 1–12 exist in the E-isomeric form, which stabilized by inter- and intramolecular noncovalent interactions. Solvatochromic behavior on UV–vis absorption spectra of azo dyes 7–12 were studied in CH2Cl2, DMF and MeOH, which λmax is dependent on the attached substituents at para- position of aromatic moiety.

The efficiency of (2E,4E)-1-(2-hydroxy-5-methylphenyl)-5-phenyl-2,4-pentadiene-1-one (1), (2E)-3-[2-(allyloxy)-5-bromophenyl]-1-(2-hydroxy-5-methylphenyl)-2-propen-1-one (2), (E)-4-methyl-2-(3-methyl-4-styryl-4.5-dihydrobenzoisoxazol-6-yl)phenol (3) and 2-{4-[2-(allyloxy)-5-bromophenyl]-3-methyl-4.5-dihydro-1.2-benzisoxazol-6-yl}-4-methylphenol (4) as corrosion inhibitors have been studied by weight loss measurements for St-3 mild steel specimen in brine-kerosene mixture. The corrosion rates of St‑3 steel decreased with increase in concentration of the studied compounds.

The structure and dielectric measurements made on the nanocomposites based on PP polypropylen and TiO2 nanoparticles are reported in this paper. It has been defined that, the incorporation of TiO2 ...

The new nickel coordination polymer [Ni(HL1) (CH3OH)2]n (1) and co-crystal H3L1∙DMF (2) were obtained by reaction of NiCl2·2H2O with 2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene) hydrazineyl)benzoic acid (H3L1) in the presence and absence of triethylamine, respectively, in a mixture of methanol and dimethylformamide (DMF) (20:1, v/v). Reaction of CuCl2·2H2O with H3L1 in the presence of 2,2'-(methylazanediyl)bis (ethan-1-ol) (HR) in methanol yields [Cu(HR)2(H2L1)2] (3), whereas treatment of this copper salt with sodium 2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene)hydrazineyl)benzenesulfonate (NaH2L2) in a mixture of acetone and water (10:1, v/v) produces [Cu(HL2) (H2O)2]∙2(H2O)∙{(CH3)2C = O} (4). Compounds 1−4 were characterized by IR and ESI-MS spectroscopies, elemental and X-ray crystal structural analyses, and tested as catalyst for the Henry reaction of aliphatic and aromatic aldehydes with nitroethane in different solvents such as acetonitrile, methanol or water. Good yields (up to 87%) and diasteroselectivities (syn/anti 77:23) were observed in the reactions catalyzed by 3 in water.

Two known lanthanide complexes, [KLa(HL 1 ) 2 {(CH 3 ) 2 NCHO} 2 (H 2 O) 3 ] ( 1 ) and [Sm(H 2 O) 9 ]( E -H 2 L 2 ) 3 ·2H 2 O ( 2 ) were prepared by reaction of lanthanum(III) and samarium(III) nitrates with potassium 3-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl)-2-hydroxy-5-nitrobenzenesulfonate (KH 2 L 1 ) and potassium ( E,Z )-5-chloro-3-(2-(1,3-dioxo-1-phenylbutan-2-ylidene)hydrazinyl)-2-hydroxybenzenesulfonate (KH 2 L 2 ), respectively. Catalytic activities of 1 and 2 were evaluated in the cyanosilylation of aldehydes with trimethylsilyl cyanide in different solvents such as tetrahydrofuran, dichloromethane or methanol. Complex 1 was found to be efficient catalyst for the cyanosilylation reaction in methanol medium at room temperature, producing cyanohydrin trimethylsilyl ethers with good yields (76–99%).

In the present study, the effect of size distribution of magnetite nanoparticles in a PVDF matrix on the magnetic properties of PVDF + Fe3O4 nanocomposites was experimentally and theoretically investigated. The size distribution of nanoparticles in polymer matrix and morphology of the nanocomposites were studied by the means of scanning electron microscopy and atomic force microscopy. It was found that when the Fe3O4 nanoparticles are introduced into the polymer matrix, their coagulation takes place. The increase in the size of the particles depends on their concentration in the polymer matrix, the type of polymer (polar, non-polar, its viscosity, etc.), reaction temperatures, etc. In addition, when Fe3O4 nanoparticles are introduced into the polymer network, the oxidation of the surface layer of particles occurs and the magnetic size decreases. Consequently, the reduced magnetic properties may also be observed. The hysteresis loops have been recorded in small magnetic field range. It was found that the magnetic hysteresis parameters depend on the size and concentration of Fe3O4 nanoparticles. Theoretical calculations were compared with experimental results obtained from M(H) measurements. The reasons of differences between theoretical and experimental results have been explained.

Different solids consisting in hydrous zirconia were synthesized by the water in oil microemulsion technique (ME series). For comparative purposes, diverse solids were also obtained by the conventional sol-gel method (P-series). The solids were tested for liquid-phase selective hydrogenation of furfural to furfuryl alcohol, using propan-2-ol as the hydrogen donor (Meerwein–Ponndorf–Verley process). The best results corresponded to catalysts calcined at 200 °C which consisted in amorphous solids with surface areas of ca 200 m2/g. The presence of some surfactant remaining from the synthetic process in solids obtained through the microemulsion technique favored selectivity to furfuryl alcohol with values ≥98%. Results were explained by the steric hindrance of furfural by the surfactant molecules in micelles thus favoring the interaction of the substrate with hydroxyl groups in hydrous zirconia through the C O group. Application of microwave irradiation accelerated the reaction (15–30 times) as compared to conventional heating.

In this article, we report about the synthesis of magnetic polymer nanocomposites comprising magnetite (Fe3O4) nanoparticles in a polyethylene (PE) matrix. The structure and composition of nanocomposite materials using scanning electron microscopy and atomic force microscopy have been studied. It has been defined that the agglomeration of nanoparticles does not occur, by increasing the volume content of nanoparticles up to 60%, and Fe3O4 nanoparticles act out like single-domain particles. It has also been revealed that nanocomposites based on PE + Fe3O4 with nanoparticle content in a polymer matrix up to 60% behave like superparamagnetic particles. It has also been revealed that the PE + Fe3O4-based nanocomposites effectively absorb the electromagnetic waves in the high frequency range of 0.1–30 GHz. It is shown that the properties of ultrahigh electromagnetic waves can be varied by varying the thickness of the nanocomposite films and the concentration of Fe3O4 nanoparticles.

Convenient and environmentally friendly synthesis of Co9S8/PVA, CoxSy/EG and CoxSy/3-MPA nanocomposites were carried out in the presence of ultrasonic irradiation by the liquid phase synthesis of the sonochemical method. For the synthesis, cobalt acetate tetrahydrate [Co(CH3COO)2·4H2O] and sodium sulfide (Na2S·9H2O) were used as a cobalt and sulfur precursor, respectively. Polyvinyl alcohol (PVA), ethylene glycol (EG) and 3-mercaptopropionic acid (3-MPA) were used as a capping agent and surfactant. The structural, optical properties and morphology of nanocomposites were characterized using X-ray diffractometer (XRD), Ultraviolet/Visible Spectroscopy (UV–Vis), Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The optical band gap of Co9S8/PVA is 1.81 eV and for CoxSy/EG is 2.42 eV, where the direct band gap of bulk cobalt sulfide is (0.78–0.9 eV). The wide band gap indicates that synthesised nanocomposites can be used in the fabrication of optical and photonic devices. The growth mechanisms of the Co9S8, CoS2 and Co3S4 nanoparticles were discussed by the reactions. The effects of sonication time and annealing temperature on the properties of the nanoparticles have been studied in detail.

Reaction of bis(4-hydrazinylphenyl)methane with 4-substitutedbenzaldehyde in the presence of CH3COONa in EtOH at 80 °C yields bis(4-((E)-2-(4-substitutedbenzylidene)hydrazinyl)phenyl) methane [−N(CH3)2 1, −F 2, −Cl 3, −NO2 4], which subsequently in the presence of CCl4, CuCl and tetramethylethylenediamine in DMSO undergoes Cu-catalyzed olefination products, bis(4-((E)-(2,2-dichloro-1-(4-substitutedphenyl)vinyl)diazenyl)phenyl)methane [−N(CH3)2 5, −F 6, −Cl 7, −NO2 8], respectively. All compounds were characterized by IR (for 1–4), 1H and 13C NMR spectroscopies, elemental and X-ray diffraction analysis (for 7 and 8). No only intermolecular hydrogen and intramolecular N⋯Cl tetrel bonds, but also the Cl⋯Cl and Cl⋯O types of halogen binding were found in the structures of 7 and 8, respectively. The collected data confirm that bis-azodyes 5–8 exist in DMSO solution and in solid state exclusively in the E-isomeric form, being stabilized by noncovalent interactions. Solvent effects on the UV–vis absorption spectra of 5−8 were studied in CH2Cl2, DMF and EtOH, which λmax is dependent on the type of substituents attached para-position of aromatic moiety.

Ethyl 3,3,5,5-tetracyano-2-hydroxy-2-methyl-4,6-diphenylcyclohexane-1-carboxylate was synthesized for the first time by three-component condensation of benzaldehyde with ethyl acetoacetate and malononitrile in the presence of trichloroacetic acid. The product structure was proved by X-ray analysis.

NH3 is a type of foul smelling gas, when breathed beyond a comfortable level, is extremely hazardous to human health. Developing of room-temperature ammonia sensors are one of the challenging task in research. Manganese ferrites and cobalt doped manganese ferrites nanoparticles were successfully produced in this work, and used as a sensing material for ammonia gas sensor, also getting the better results at room temperature. The synthesized materials were confirmed by various characterization techniques namely XRD, SEM & EDAX, FTIR, and DRS. Three different weight percentage (1, 3, and 5 wt%) of Co is doped with MnFe2O4 nanomaterial and study the optical properties and the ammonia sensing ability comparatively. From that 5 wt% Co: MnFe2O4 nanoparticles shows good sensing percentage of about 75.3 %.

The new mononuclear nickel(II) complexes [Ni(HL 1 )(H 2 O) 2 (CH 3 OH)] ( 1 , NaH 2 L 1 = sodium ( Z )-2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene)hydrazinyl)benzenesulfonate) and [Ni(H 2 L 2 ) 2 (H 2 O) 4 ] [(CH 3 ) 2 S O) 2 ] ( 2 , H 3 L 2 = (Z)-2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene)hydrazinyl)benzoic acid) were synthesized and characterized by IR and ESI-MS spectroscopies, elemental and X-ray crystal structural analyses. Both compounds 1 and 2 act as homogenous catalysts for the diastereoselective nitroaldol (Henry) reaction of aliphatic and aromatic aldehydes with nitroethane in different solvents such as acetonitrile, methanol or water. Complex 1 was found to be the more efficient catalyst for the Henry reaction in aqueous medium, providing β-nitroalcohols with good yields (67–82%) and diastereoselectivities ( syn/anti 59:41–70:30).

The capability of the ammonium salt of the cross-linked maleic acid–allylpropionate–styrene terpolymer for the adsorption of Cu2+ from aqueous solutions was examined. Effect of the various experime...

β-NiS nanoparticles (NPs) grown through SILAR technique into functionalized nitrile butadiene rubber (FNBR) were used for the synthesis of CuS-NiS/FNBR and Cu1.8S-Ni3S4/FNBR nanocomposites (NCs). The evaluated band gap decreased from 2.8 eV to 2.3 eV and 2.21 eV using 0.25 M of CuSO4 × 5H2O and 0.5 M of CuCl2 × 2H2O, respectively. The effect of copper precursors and concentration of Cu2+ ions on the particle size, chemical composition of NCs and properties has been discussed in detail. Different structural phases of nickel sulfide and copper sulfide were obtained using NiS/FNBR nanocomposites as a precursor for ion exchange reaction by Cu2+ ions. Properties of CuxS-NiySz/FNBR and CuS-NiySz/FNBR nanocomposites obtained after modification have been studied and compared with initial nanocomposite of NiS/FNBR. The average particle size increased from 8.5 nm to 13.5 nm and 15 nm after ion exchange modification. By EPR spectrum the superhyperfine splitting is seen in the spectrum of CuS-NiySz/FNBR, ACu = 107.3 G. In perpendicular section the bandwidth of the spectrum (ΔH) is equal to 930 G. Recording to SEM images very clearly imaged spherical nanoparticles have been observed.

A series of polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles have been prepared using a multicomponent condensation reaction between aromatic al...

Two known organotin(IV) complexes, [Sn(C6H5)3HL1] (1) and [Sn(C2H5)2(1κO,2κO-H3L2) (1κO2-H3L2) (μ3-O)]2 (2), were prepared upon interaction of Ph3SnCl and Et2SnO with 2-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl)benzoic acid (H2L1) and 2-(2-(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene) hydrazinyl)benzoic acid (H4L2), respectively, in toluene solution. Both complexes are applied as catalysts in cyanosilylation of aldehydes. Complex 2 shows a high catalytic activity in the cyanosilylation reaction of a variety of aliphatic and aromatic aldehydes with trimethylsilyl cyanide yielding to the corresponding cyanohydrin trimethylsilyl ethers (yields up to 99%) in methanol and at room temperature.