Search

Your search keyword '"Yuri, Fujii"' showing total 4 results
Start Over Author "Yuri, Fujii" Topic chemistry
4 results on '"Yuri, Fujii"'

1. Biosynthesis of sorokinianin a phytotoxin of Bipolaris sorokiniana: Evidence of mixed origin from the sesquiterpene and TCA pathways

Author

Hiromitsu Nakajima, Takashi Hamasaki, Yukie Toratsu, Masakatsu Ichinoe, and Yuri Fujii

Subjects
biology, Metabolite, Organic Chemistry, Phytotoxin, Sesquiterpene, Bipolaris, biology.organism_classification, Biochemistry, Citric acid cycle, chemistry.chemical_compound, Metabolic pathway, chemistry, Biosynthesis, Succinic acid, Drug Discovery
Abstract

Incorporation of sodium [1,2- 13 C 2 ]acetate confirmed that sorokinianin is, except for the C 3 portion, a sesquiterpene and indicated that the C 3 portion is derived from the acetyl CoA-related metabolic pathway. Results of replacement culture experiments suggested that the precursor of sorokinianin is prehelminthosporol, a major metabolite of B. sorokiniana OB-25-1, and a TCA cycle intermediate. Incorporation of [2,3- 13 C 2 ]succinic acid confirmed that the origin of the C 3 portion is a TCA cycle intermediate.

Published
1998

2. ChemInform Abstract: Convenient Synthesis of 1,3-Dihydroisobenzofurans by Hydriodic Acid-Catalyzed Cyclization of 2-Vinylbenzyl Alcohols

Author

Kazuhiro Kobayashi, Miyuki Tanmatsu, Kazuaki Shikata, Yuri Fujii, Hisatoshi Konishi, and Shuhei Fukamachi

Subjects
Chemistry, Acid catalyzed, Butyllithium, Organic chemistry, General Medicine
Abstract

A new and short process has been developed for the preparation of 1,1,3-tri- and 1,1,3,3-tetra-substituted 1,3-dihydroisobenzofurans (phthalanes) from α-substituted 2-bromostyrenes. The method involves addition of α-substituted 2-lithiostyrenes, generated by the bromine-lithium exchange between α-substituted 2-bromostyrenes and butyllithium, to aliphatic aldehydes or ketones, followed by hydriodic acid catalyzed cyclization of the resulting 2-vinylbenzyl alcohols.

Published
2010

3. ChemInform Abstract: Biosynthesis of Sorokinianin a Phytotoxin of Bipolaris sorokiniana: Evidence of Mixed Origin from the Sesquiterpene and TCA Pathways

Author

Hiromitsu Nakajima, Takashi Hamasaki, Yukie Toratsu, Masakatsu Ichinoe, and Yuri Fujii

Subjects
biology, Metabolite, General Medicine, Phytotoxin, Bipolaris, biology.organism_classification, Sesquiterpene, Terpene, Metabolic pathway, chemistry.chemical_compound, Biochemistry, Biosynthesis, chemistry, Succinic acid
Abstract

Incorporation of sodium [1,2- 13 C 2 ]acetate confirmed that sorokinianin is, except for the C 3 portion, a sesquiterpene and indicated that the C 3 portion is derived from the acetyl CoA-related metabolic pathway. Results of replacement culture experiments suggested that the precursor of sorokinianin is prehelminthosporol, a major metabolite of B. sorokiniana OB-25-1, and a TCA cycle intermediate. Incorporation of [2,3- 13 C 2 ]succinic acid confirmed that the origin of the C 3 portion is a TCA cycle intermediate.

Published
2010

4. Convenient Synthesis of 1,3-Dihydroisobenzofurans by Hydriodic Acid-Catalyzed Cyclization of 2-Vinylbenzyl Alcohols

Author

Kazuaki Shikata, Kazuhiro Kobayashi, Shuhei Fukamachi, Miyuki Tanmatsu, Yuri Fujii, and Hisatoshi Konishi

Subjects
Pharmacology, Phthalane, chemistry.chemical_compound, chemistry, Acid catalyzed, Organic Chemistry, Butyllithium, Organic chemistry, Analytical Chemistry
Abstract

A new and short process has been developed for the preparation of 1,1,3-tri- and 1,1,3,3-tetra-substituted 1,3-dihydroisobenzofurans (phthalanes) from α-substituted 2-bromostyrenes. The method involves addition of α-substituted 2-lithiostyrenes, generated by the bromine-lithium exchange between α-substituted 2-bromostyrenes and butyllithium, to aliphatic aldehydes or ketones, followed by hydriodic acid catalyzed cyclization of the resulting 2-vinylbenzyl alcohols.

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results