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An efficient, one-pot and multi-component synthesis of trans -perfluoroalkylated [1,3]oxazino[2,3- a ]isoquinoline derivatives is described. Moderate to excellent yields have been achieved under mild conditions. A plausible mechanism for this type of cyclization is proposed. In addition, isoquinolines as the nucleophilic reagent have been examined. Furthermore, excellent regioselectivity and diastereoselectivity can be observed in this reaction.

In order to study the effects of electric field intensity and distribution on flame propagation speed, the paper investigated the flame propagation of premixed CH 4 /O 2 /N 2 mixtures under direct-current (DC) electric fields at an excess air ratio of 1.4. Different high-voltage electrodes were chosen in the experiment in two aspects: electrodes size (the outer-diameter of high-voltage electrodes) and electrodes structure. Results show that the flame propagation speed increases significantly with the voltage applied to the high-voltage electrodes. Secondly, the electric field intensity can significantly affect the flame propagation, and it can be observed that the mean flame propagation speed increases linearly with the mean electric field intensity under fixed high-voltage electrodes. In addition, electric field distribution is another important influence factor on the flame propagation. Specifically, the effect of the electric field on the flame propagation speed increases apparently with the uniformity coefficient, so a uniform electric field works better than an uneven one for promoting the flame propagation speed. In fact, with the smallest uniformity coefficient of 0.21, the electric field under the 60 mm-diameter mesh electrodes has the most uniform electric field, while the effect of that on the flame propagation is the strongest, with the highest mean flame propagation speed of 1.25 m/s at an applied voltage of −10 kV. The results substantiate the importance of the electric field intensity and distribution on promoting the flame propagation speed of lean combustion.

A multicomponent reaction involving quinolines, methyl perfluoroalk-2-ynoates and aromatic aldehydes for the synthesis of perfluoroalkylated fused [1,3]oxazine derivatives has been described. The whole process is carried out under mild conditions and furnishes the desired products in good yields. Furthermore, excellent regioselectivity and diastereoselectivity can be observed in this reaction.

An efficient, one-pot, three-component procedure for the synthesis of fluorinated oxazinoisoquinolines with excellent regioselectivity and diastereoselectivity is presented.

A new multicomponent reaction involving methyl perfluoroalk-2-ynoates, quinolines and aldehydes leading to the sole formation of cis-perfluoroalkylated [1,3]oxazino[3,2-α]quinolines, is developed.