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Omega-3 fatty acids are related to healthy aging all over life. A moment ago, from fish, source omega-3 fatty acids DHA and EPA have been related with fetal development in AD and cognition related problems. Nevertheless, since the human body does not effectively produce few omega-3 fatty acids, while obtaining from marine sources. The brain is extremely augmented with lipids bilayers. Therefore, it is accountable to undertaken that the combination of different fatty acids within brain ha importance for brain functioning, counting neuropsychiatric and cognition development. To know the special effects form fatty acids ingestion, we need to depend on the mutual evaluation of experimental studies, observations, and interventional studies. The brain is enriched with lipid bilayers of omega-3 fatty acid constituents like DHA and EPA may have lots of effects on the brain. The potential function of omega-3 fatty acid, DHA, and EPA in the inhibition of cognition degeneration including AD has involved key importance from the last few decades. Additionally, AD has delivered the utmost positive sign to backing the situation that inflammation gives to a neurodegenerative disorder. The main etiology of the AD is unidentified, but genetic and ecological parameters are supposed, like family history, poor lifestyle and poor diet, the existence of any chronic disease like cardiovascular disease, increased age, and diabetes. It is assumed 174that primarily, management or prevention of inflammation may delay the indications of AD. Normally, changes the brain physiology with increased aging, comprising reduction of elongated chain omega-3 fatty acids as well as the brain of AD patients have reduced the DHA presence. Provided supplementary DHA can decrease the indications of inflammations. The health-related benefits of omega-3 fatty acids are really appreciable. Presently, there is no evidence of maintenance or confirmation of that modifiable risk parameters like herbal medicines, nutritional supplements, modified diet, etc. are associated with reduced the risk factors of AD or the cognition failure. Even though, multiple studies are showing that lifestyle and diet-related parameters are the main risk factors for AD and cognition behavior. This chapter basically focused on the different functions of omega-3 fatty acids mainly DHA and EPA in different neurodegenerative diseases and disorders.

Antimicrobial resistance is a budding problem that has obstructed the world of nearby starting of the end for the old generation antimicrobials. Nanoparticles give the positive response to anti-microbial resistance, which could trigger the innovation and makes new generation of anti-microbials for the treatment in future using nanotechnology based drug delivery. Nanotechnology is progressively exhausting technology both in nano-medicine and nano-material for the diagnosing and treatment of innumerable diseases and disorders. Nanoparticles presenting worthy potential in treatment of bacterial infection, where developed several drug deliveries like microbial triggered drug delivery, micro-encapsulation, pH sensitive, surface charge changing nanoparticles for treating various bacterial infection. It will be possible by developing novel formulation into nanotechnologies can increase therapeutically longest duration to act against microbial infection. However, many unique physicochemical characteristics of nanoparticles can offer new antibacterial modes of action which can be explored. Antimicrobial nanoparticles and nanonized drug delivery transporters have arisen as effective agents against 134various microbial infections. Nanoparticles having distinctive properties other than their small and tailored particle size like improved reactivity, functionalizable structure and appreciable surface area. In contrast to the conventional antimicrobial agents, nanoparticles help in reducing the toxicity, controlling resistance and reducing the cost. Additionally, nanoparticles are also improving the therapeutic and pharmacokinetic properties of the antimicrobial agents. Nanotechnology also helps in development of cost effective, accurate and fast diagnosis, detection and management by treating microbial agents. They were working as nano-anti microbial agents and their extensive ability of treating diseases and disorders. Besides, nanoparticles use multiple biological pathways to apply their antimicrobial mechanisms like destruction of cell wall, DNA inhibition, and enzyme synthesis. Furthermore, the preparation of these nanoparticles is more cost effective than antibiotics synthesis and also more stable for long term stability and they are also withstand to grating condition. In present chapter, we are focusing upon the nanoparticles based drug delivery system as promising technology in microbial pharmaceutics and extensive applications thereof.