Search

Niosomes are considered as novel nano-carrier in the drug delivery systems. These are much more stable than other nano-carriers like liposomes and nanoparticles. It is an example for targeted and control release of medication. The drug is entrapped into lipid core so that it prevents the drug from leaching. Here the drug will be targeted only to the desired cell/tissue and not to the non-targeted cells. By giving this formulation we can thereby reduce the dose of the drug and toxicity. This review article mainly emphasizes on the potential applications of niosomes in targeted drug delivery system. Keywords: niosomes, nanocarriers, targeted drug delivery.

The recent innovative advance in nanotechnology has led to the development of targeted drug delivery system. Targeting a molecule to a particular site with the help of a drug delivery system efficiently requires the use of specialized drug delivery systems. The invention of Nano sponges has become a significant step in overcoming the problems associated with conventional drug delivery systems. These are able to carry both hydrophilic and hydrophobic drugs. Nano sponge technology widely provide the controlled and predictable release of the drug to the targeted site. The Nano sponge particles circulate around the body and get attached with the target site and release the drug. A wide variety of drugs can be incorporated in the Nano sponge formulation since it possess a porous structure in nature. Nano sponge technology has been studied widely for the drug delivery by oral administration, topical administration and parenteral administration. Nano sponges can be used to prevent drug and protein degradation. Another important characteristic of Nano sponge is that they can improve the solubility of poorly water soluble drug. In this review advantages, composition, method of preparation, evaluation and application of different formulations of drugs and recent studies on Nano sponge have been discussed.

Nanosuspensions are colloidal dispersions and biphasic system consisting of drug particles dispersed in an aqueous vehicle in which the diameter of the suspended particle is less than 1μm in size. Many drugs including antibiotics are having poor solubility. Nanosuspensions have proven to be a better alternative over other approaches currently available for improving bioavailability of such drugs with low solubility. This review describes the methods of pharmaceutical nanosuspension of antibiotic formulations and pharmaceutical applications in drug delivery. Keywords: Nanosuspension, Bioavailability, Solubility