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The integration of two-dimensional Ti3C2Tx nanosheets and other materials offers broader application options in the antibacterial field. Ti3C2Tx-based composites demonstrate synergistic physical, chemical, and photodynamic antibacterial activity. In this review, we aim to explore the potential of Ti3C2Tx-based composites in the fabrication of an antibiotic-free antibacterial agent with a focus on their systematic classification, manufacturing technology, and application potential. We investigate various components of Ti3C2Tx-based composites, such as metals, metal oxides, metal sulfides, organic frameworks, photosensitizers, etc. We also summarize the fabrication techniques used for preparing Ti3C2Tx-based composites, including solution mixing, chemical synthesis, layer-by-layer self-assembly, electrostatic assembly, and three-dimensional (3D) printing. The most recent developments in antibacterial application are also thoroughly discussed, with special attention to the medical, water treatment, food preservation, flexible textile, and industrial sectors. Ultimately, the future directions and opportunities are delineated, underscoring the focus of further research, such as elucidating microscopic mechanisms, achieving a balance between biocompatibility and antibacterial efficiency, and investigating effective, eco-friendly synthesis techniques combined with intelligent technology. A survey of the literature provides a comprehensive overview of the state-of-the-art developments in Ti3C2Tx-based composites and their potential applications in various fields. This comprehensive review covers the variety, preparation methods, and applications of Ti3C2Tx-based composites, drawing upon a total of 171 English-language references. Notably, 155 of these references are from the past five years, indicating significant recent progress and interest in this research area. [ABSTRACT FROM AUTHOR]

Purpose: The study mainly aimed to determine the biological function of a novelly synthesized phenanthroimidazole derivative, named L233, and to explore its potential mechanisms.Methods: Cell survival was examined using the MTT assays, and the DNA-damaging role of L233 was explored using the comet assay. Moreover, the western blotting assays and immunofluorescence assays were used to detect DNA damage biomarkers. Afterward, the flow cytometry was used to assess the effects of L233 on cell cycle distribution. As for the detection of cell apoptosis upon L233 treatment, the Hoechst 33342 staining, flow cytometry, and western blotting assays were all put into practice.Results: We find that L233 inhibits tumor cell growth more efficiently and safely than cisplatin. Moreover, it is a DNA-damaging agent, interrupting the cell cycle G1/S checkpoint transition and inducing cell apoptosis by not only activating ATM/CHK1 signaling pathway, but also targeting CHK1 to reduce the expression of RAP80 and PARP-1 to compromise the DNA damage repair in tumor cells.Conclusions: In summary, L233 is a promising anticancer drug for the development of novel chemotherapies in the future. [ABSTRACT FROM AUTHOR]

Fine-tuning of effective pore size of microporous materials is necessary to achieve precise molecular sieving properties. Herein, we demonstrate that room temperature ionic liquids can be used as cavity occupants for modification of the microenvironment of MOF nanocages. Targeting CO2 capture applications, we tailored the effective cage size of ZIF- 8 to be between CO2 and N2 by confining an imidazoliumbased ionic liquid [bmim][Tf2N] into ZIF-8's SOD cages by in-situ ionothermal synthesis. Mixed matrix membranes derived from ionic liquid-modified ZIF-8 exhibited remarkable combinations of permeability and selectivity that transcend the upper bound of polymer membranes for CO2/N2 and CO2/CH4 separation. We observed an unusual response of the membranes to varying pressure, that is, an increase in the CO2/CH4 separation factor with pressure, which is highly desirable for practical applications in natural gas upgrading. [ABSTRACT FROM AUTHOR]

The article discusses research on a water stable metal-organic framework with optimal features for carbon dioxide (CO2) capture. It mentions the reduction of anthropogenic CO2 emission from post-combustion flue gas to minimize its effect on the environment. It also offers information on ideal adsorbed solution theory (IAST).

A ZIF-9-67 hybrid membrane on α-Al2O3 support was prepared using mixed-linker synthesis. The gas permeation and selectivity data demonstrate that this membrane may have potential applications for efficient CO2 capture from several industrial mixtures. [ABSTRACT FROM AUTHOR]

Abstract: A new porous Zr-based MOF was synthesized by the solvothermal method using 2,6-naphthalenedicarboxylic acid (NDC) as the organic linker, and its luminescent performance and stability were investigated systematically. The material synthesized exhibits quite high chemical stability in addition to exceptional high thermal stability, better than the existing luminescent MOFs. The experiments combining with computations indicate that the electron transfer from inorganic moieties to organic moieties contributes to the luminescent behavior of the Zr-NDC MOF besides the NDC ligand. As far as we know, this is the first study of investigating the luminescent behaviors of such Zr-based MOFs. Moreover, the cycling measurements demonstrate an interesting prospect for the long-term reusability of this material. The results obtained in this work may provide useful information for the design of physicochemically stable MOFs with permanent porosity in sensing applications in the future. [Copyright &y& Elsevier]