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Abstract: Benzoquinazolin-2-one derivatives were synthesized by using a catalytic amount of task specific ionic liquid, [1-methyl-3-(4-sulfobutyl)imidazolium-4-methylbenzenesulfonate] through a one-pot multicomponent Biginelli reaction of α-tetralone, aldehyde, and urea/thiourea in excellent yields within a short reaction time. Mechanism studies suggest that the reaction proceeds through iminium intermediate and C2-H of the TSIL plays a major role on its catalytic activity. The catalyst has been reused four times without any significant loss in catalytic activity. Large scale reaction by using this TSIL suggests the applicability of this methodology for bulk synthesis of quinazolinone derivatives. [Copyright &y& Elsevier]

In this paper, a simple and efficient protocol for the chemoselective sulfonation of indoles using aryl sulfonyl chlorides in the presence of CuI is reported. The reaction proceeds under mild conditions and is applicable to indoles bearing a selection of functional groups without NH protection. [ABSTRACT FROM AUTHOR]

A sulfonic-acid-functionalized ionic liquid is used as a Brønsted acid catalyst for the efficient synthesis of indole derivatives in good-to-high yields at room temperature under solvent-free conditions. The catalyst can be reused for ten consecutive runs without significant loss of activity. [ABSTRACT FROM AUTHOR]

A diastereoselective synthesis of pyrrolidinooxazolidines was achieved by a metal-free, base-promoted reaction of pyrrolidine and aromatic aldehydes under microwave irradiation. The rare functionalization of an sp3 C–H bond probably results from an in situ generated azomethine ylide that undergoes cycloaddition with aldehydes. [ABSTRACT FROM AUTHOR]

Sulfobutyl substituted ionic liquid (IMS) efficiently catalyzes the Biginelli reaction of α-tetralone, aldehyde, and urea or thiourea to afford benzoquinazoline derivatives. [ABSTRACT FROM AUTHOR]

Abstract New unsymmetrically substituted 5,5′-diaryl-2,2′-bypiridine "push-pull" fluorophores were prepared in good yields via the "1,2,4-triazine method"/Suzuki coupling reaction sequence. The obtained fluorophores contain the "push-pull" system with donor and acceptor moieties arranged in a D-π-A-π-D fashion, and that provides both the prospective photophysical properties and unique solvatocromic effects for the most representative compounds. Graphical abstract Image 1 Highlights • Synthesis of unsymmetrically substituted 5,5′-diaryl-2,2′-bipyridine fluorophores. • "1,2,4-Triazine" methodology and cross-coupling reactions were done. • Photophysical studies of the present reported fluorophores were investigated. • Single crystal X-ray diffraction studies were performed. [ABSTRACT FROM AUTHOR]