1. Chelating properties of α-oximinocarboxamides—I α-Oximinophenylacetamide isomers
- Author
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Hamed M. El-Fatatry and Dominick A. Coviello
- Subjects
chemistry.chemical_classification ,chemistry.chemical_compound ,Ketone ,Carbon atom ,chemistry ,Stereochemistry ,Amide ,Functional group ,Chelation ,Amine gas treating ,Oxime ,Medicinal chemistry ,Analytical Chemistry - Abstract
Various polyfunctional oximes chelate with metals pro vided that the other functional group is proximal to the oxime and contains a good donor atom or is a good donor itself. Thus α-oximinocarboxamides are potential chelating agents of analytical value since the amide function attached to the carbon atom bearing the oxime has two groups capable of functioning as donors (ketone and amine). Two isomers of α-oximinophenylacetamide (AOPA) were obtained by two different synthetic routes, and structures were assigned by spectrometric methods. syn-AOPA was found to have chelating properties, but the anti-isomer did not. The synthesis and details of structure assignments are reported here.
- Published
- 1971
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