7 results on '"Won, Sae-Yeon"'
Search Results
2. Influence of ABO blood type on the outcome after non-aneurysmal subarachnoid hemorrhage
- Author
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Dubinski, Daniel, Won, Sae-Yeon, Behmanesh, Bedjan, Kashefiolasl, Sepide, Geisen, Christof, Seifert, Volker, Senft, Christian, and Konczalla, Juergen
- Published
- 2018
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3. Beware of Nihilism: Favorable Outcome despite Poor Admission Status in Posterior Circulation Aneurysms after Aneurysmal Subarachnoid Hemorrhage.
- Author
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Brawanski, Nina, Kashefiolasl, Sepide, Won, Sae-Yeon, Berkefeld, Joachim, Hattingen, Elke, Senft, Christian, Seifert, Volker, and Konczalla, Juergen
- Subjects
INTRACRANIAL aneurysms ,POSTERIOR cerebral artery ,CEREBRAL vasospasm ,SUBARACHNOID hemorrhage ,ANTERIOR cerebral artery ,ANEURYSMS ,INTRACRANIAL aneurysm ruptures ,RUPTURED aneurysms - Abstract
Objective As shown in a previous study, aneurysm location seems to influence prognosis in patients with subarachnoid hemorrhage (SAH). We compared patients with ruptured aneurysms of anterior and posterior circulation, undergoing coil embolization, concerning differences in outcome and prognostic factors. Methods Patients with SAH were entered into a prospectively collected database. We retrospectively identified 307 patients with aneurysms of the anterior circulation (anterior cerebral artery, carotid bifurcation, and middle cerebral artery) and 244 patients with aneurysms of the posterior circulation (aneurysms of the basilar artery, posterior inferior cerebellar artery, posterior communicating artery and posterior cerebral artery). All patients underwent coil embolization. The outcome was assessed using the modified Rankin Scale (mRS; favorable [mRS 0–2] vs. unfavorable [mRS 3–6]) 6 months after SAH. Results In interventionally treated aneurysms of the anterior and posterior circulation, statistically significant risk factors for poor outcome were worse admission status and severe cerebral vasospasm. If compared with patients with ruptured aneurysms of the anterior circulation, patients with aneurysms of the posterior circulation had a significantly poorer admission status, and suffered significantly more often from an early hydrocephalus. Nonetheless, there were no differences in outcome or mortality rate between the two patient groups. Conclusion Patients with a ruptured aneurysm of the posterior circulation suffer more often from an early hydrocephalus and have a significantly worse admission status, possibly related to the untreated hydrocephalus. Nonetheless, the outcome and the mortality rate were comparable between ruptured anterior and posterior circulation aneurysms, treated by coil embolisation. Therefore, despite the poorer admission status of patients with ruptured posterior circulation aneurysms, treatment of these patients should be considered. [ABSTRACT FROM AUTHOR]
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- 2021
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4. Reactive Thrombocytosis in Non-aneurysmal Subarachnoid Hemorrhage.
- Author
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Dubinski, Daniel, Won, Sae-Yeon, Behmanesh, Bedjan, Brawanski, Nina, Seifert, Volker, Senft, Christian, and Konczalla, Juergen
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SUBARACHNOID hemorrhage , *CEREBRAL vasospasm , *CEREBRAL ischemia , *INTERNATIONAL organization , *HYDROCEPHALUS - Abstract
Background The role of reactive thrombocytosis in non-aneurysmal subarachnoid hemorrhage (NA-SAH) is largely unexplored to date. Therefore, the impact of a quantitative thrombocyte dynamic in patients with NA-SAH and its clinical relevance were analyzed in the present study. Methods In this retrospective analysis, 113 patients with nontraumatic and NA-SAH treated between 2003 and 2015 at our institution were included. World Federation of Neurosurgical Societies admission status, cerebral vasospasm, delayed infarction, hydrocephalus, need for ventriculoperitoneal (VP) shunt, and Fisher grade were analyzed for their association with reactive thrombocytosis. Results Reactive thrombocytosis was not associated with hydrocephalus (p ≥ 0.05), need for VP shunt implantation (p ≥ 0.05), cerebral vasospasm (p ≥ 0.05), or delayed cerebral ischemia (p ≥ 0.05). Conclusion Our study is the first to investigate the role of thrombocyte dynamics, reactive thrombocytosis, and the clinical course of NA-SAH patients. Our analysis showed no significant impact of thrombocyte count on NA-SAH sequelae. [ABSTRACT FROM AUTHOR]
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- 2020
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5. Pain medication at ictus of subarachnoid hemorrhage—the influence of one-time acetylsalicylic acid usage on bleeding pattern, treatment course, and outcome: a matched pair analysis.
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Bruder, Markus, Kashefiolasl, Sepide, Keil, Fee, Brawanski, Nina, Won, Sae-Yeon, Seifert, Volker, and Konczalla, Juergen
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ASPIRIN ,THERAPEUTICS ,SUBARACHNOID hemorrhage ,CEREBRAL vasospasm ,CEREBRAL infarction ,DRUGS - Abstract
Acetylsalicylic acid (ASA) is a well-known and widely used analgesic for acute pain. Patients with acute headache due to subarachnoid hemorrhage (SAH) are inclined to take ASA in this situation. Due to the antithrombotic effects, ASA intake is related to higher bleeding rates in case of hemorrhage or surgical treatment. Between January 2006 and December 2016, 941 patients without continuous antithrombotic or anticoagulant medication were treated due to SAH in our institution. Fourteen of them (1.5%) had taken ASA as a single dose because of headache within 24 h before hospital admission. A matched pair analysis was performed. Admission status was good in 93% of patients with one-time use of ASA (OTA), but only in 59% of all other patients (p < 0.01). Bleeding pattern did not differ, but half of the patients with OTA had no identifiable bleeding source; this rate was significantly lower in the rest of the patients (p < 0.005). Aneurysm treatment and related complications did not differ between both groups. Cerebral vasospasm was more often only mild and rates of cerebral infarctions were lower in the OTA group but not on a significant level. Eighty-six percent of the OTA group and 84% (p = 0.8) of the matched pair control group reached favorable outcome according to mRS 6 months after SAH. Patients with OTA in case of SAH are usually in good clinical condition and bleeding pattern does not differ. In half of the patients with OTA, no bleeding source was detectable. In the case of aneurysm treatment, related complications did not differ and most of the patients reached favorable outcome. In the case of aneurysm treatment procedure, OTA does not influence treatment course and should not influence treatment decisions. [ABSTRACT FROM AUTHOR]
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- 2019
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6. Cerebral Vasospasm Due to Arteriovenous Malformation-Associated Hemorrhage: Impact of Bleeding Source and Pattern.
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Dinc, Nazife, Won, Sae-Yeon, Eibach, Michael, Quick-Weller, Johanna, Konczalla, Jürgen, Berkefeld, Joachim, Seifert, Volker, and Marquardt, Gerhard
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CEREBRAL vasospasm , *HEMORRHAGE , *CEREBRAL infarction , *SUBARACHNOID hemorrhage , *ARTERIOVENOUS malformation - Abstract
Objective: Cerebral vasospasm (CVS) after a ruptured arteriovenous malformation (AVM) is rarely reported. This study is aimed at evaluating the predictive variables in AVM hemorrhage for CVS. Methods: A total of 160 patients with ruptured AVMs were admitted to our neurosurgical department from 2002 to 2018. The frequency of cerebral vasospasm after AVM hemorrhage and the impact of AVM-associated aneurysms were evaluated. We compared different bleeding patterns, such as intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH) or a combination of both (ICH + SAH) and evaluated predictive variables for outcome in last follow-up. Results: A total of 62 (39%) patients had AAA, mostly located prenidal (75.8%). AVMs with ruptured aneurysms often resulted in ICH with SAH component (p < 0.001). Eighty-two patients (51%) presented a SAH component, and CVS occurred in 6 patients (7.3%), mostly due to a ruptured infratentorial AVM (p < 0.03). Infratentorial location and the amount of SAH component (p < 0.001) predicted the incidence of CVS significantly. Cerebral infarction was significantly associated with CVS (p < 0.02). Conclusion: SAH component and infratentorial location of ruptured AVMs may harbor a higher risk for CVS. Follow-up with angiographic imaging should be considered in patients with infratentorial AVM hemorrhage and delayed neurologic deterioration to rule out CVS. [ABSTRACT FROM AUTHOR]
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- 2019
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7. The Role of ABO Blood Group in Cerebral Vasospasm, Associated Intracranial Hemorrhage, and Delayed Cerebral Ischemia in 470 Patients with Subarachnoid Hemorrhage.
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Dubinski, Daniel, Won, Sae-Yeon, Konczalla, Jürgen, Mersmann, Jan, Geisen, Christof, Herrmann, Eva, Seifert, Volker, and Senft, Christian
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CEREBRAL vasospasm , *ABO blood group system , *SUBARACHNOID hemorrhage , *INTENSIVE care nursing , *RETROSPECTIVE studies , *PATIENTS , *THERAPEUTICS - Abstract
Objective Rupture of an intracranial aneurysm usually presents with an acute onset and requires multidisciplinary intensive care treatment and the overall death and disability rates are high. The ABO blood type is known to play an important role in hemostasis, thrombosis, and vascular NO response. The aspect of ABO blood type in onset, clinical progress, and outcome after subarachnoid hemorrhage (SAH) is largely unexplored. We conducted this study to elucidate the association of ABO blood type with the occurrence and outcome of aneurysmal SAH. Methods In our retrospective study, 470 patients with aneurysmal SAH treated at our institution were included. We performed a χ 2 test for comparison between blood types and World Federation of Neurosurgical Societies admission status, cerebral vasospasm, delayed infarction, associated intracerebral hemorrhage and Fisher grade for analysis for their association with SAH. Results No significant difference between blood type and the reviewed variables for SAH outcome were identified: World Federation of Neurosurgical Societies admission status (odds ratio, 1.12; 95% confidence interval [CI], 0.7–1.6; P = 0.56); SAH-associated intracerebral hemorrhage (odds ratio, 0.81; 95% CI, 0.5–1.3; P = 0.36); cerebral vasospasm (odds ratio, 1.08; 95% CI, 0.7–1.6; P = 0.71); DCI (odds ratio, 1.23; 95% CI, 0.8–1.8; P = 0.30); Fisher grade (odds ratio, 1.13; 95% CI, 0.7–1.6; P = 0.19). Conclusions Although a possible relationship between the ABO blood group and the clinical course of patients with SAH was hypothesized, our study showed no significant influence of patient's ABO blood type on cerebral vasospasm onset, SAH-associated intracerebral hemorrhage, or delayed infarction. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
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