B Background: b Loneliness has been proven to be associated with diverse negative consequences, especially mental health issues such as emotional distress, pain, alcohol abuse, and worse cognitive function. The mean scores of overall loneliness for patients with dependence (mean 2.54, SD 1.87) were significantly higher, compared with those without dependence (mean 1.06, SD 1.68), p=0.01. No conflict of interest Reference 1 S. Cheng, T.G. Siddiqui, M. Gossop, E.S. Kristoffersen, C. Lundqvist, The severity of dependence scale detects medication misuse and dependence among hospitalized older patients. [Extracted from the article]