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Start Over Author "Wang, Chunting" Topic cellular control mechanisms
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1. HepG2.2.15 as a model for studying cell protrusion and migration regulated by S100 proteins.

Author

Liu, Shiying, Zhou, Rui, Zhong, Jian, Nie, Chunlai, Yuan, Zhu, Zhou, Liangxue, Luo, Na, Wang, Chunting, and Tong, Aiping

Subjects
*CELL migration, *CELLULAR control mechanisms, *PROTEIN expression, *ACTIN, *POLYMERIZATION, *TUBULINS
Abstract

Highlights: [•] Seven S100 family members were almost totally undetectable in HepG2.2.15 cells. [•] S100 proteins rescue the defects in protrusion and migration of HepG2.2.15 cells. [•] S100 proteins promoted actin polymerization. [•] S100A10 may interact with β-actin, β-tubulin and annexin A2 protein. [•] Promotion of cell protrusion by S100A10 was dependent on Cdc42 activation. [Copyright &y& Elsevier]

Published
2014
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