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1. Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases.

Author

Voloshyn, Ivan, Schumann, Conrad, Cabotaje, Princess R., Zamader, Afridi, Land, Henrik, and Senger, Moritz

Subjects
*PROTEIN structure, *SCAFFOLD proteins, *CATALYSTS, *CATALYSIS, *DETECTORS
Abstract

[FeFe]-hydrogenases function as both H2 catalysts and sensors. While catalysis is well investigated, details regarding the H2 sensing mechanism are limited. Here, we relate protein structure changes to H2 sensing, similar to light-driven bio-sensors. Our results highlight how identical cofactors incorporated in alternative protein scaffolds serve different functions in nature. [ABSTRACT FROM AUTHOR]

Published
2024
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