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Your search keyword '"Hugh Malkin"' showing total 3 results
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3 results on '"Hugh Malkin"'

1. The Synthesis of C2-Symmetric and Axially Chiral Compounds for Recognition and Catalysis

Author

John Clews, Anthony D.M. Curtis, and Hugh Malkin

Subjects
Steric effects, Molecular recognition, Axial chirality, Chemistry, Organic Chemistry, Drug Discovery, Organic chemistry, Axial symmetry, Biochemistry, Catalysis
Abstract

Axially chiral amidines and guanidines, some possessing C2-symmetry, have been targeted as potential chiral catalysts for reactions of α,β-unsaturated carboxylic acids or esters. The key step in each synthesis required the coupling of two sterically demanding aromatic compounds to form atropisomeric biaryl species.

Published
2000

2. ChemInform Abstract: The Synthesis of C2-Symmetric and Axially Chiral Compounds for Recognition and Catalysis

Author

Anthony D.M. Curtis, John Clews, and Hugh Malkin

Subjects
Steric effects, Chemistry, General Medicine, Axial symmetry, Combinatorial chemistry, Catalysis
Abstract

Axially chiral amidines and guanidines, some possessing C2-symmetry, have been targeted as potential chiral catalysts for reactions of α,β-unsaturated carboxylic acids or esters. The key step in each synthesis required the coupling of two sterically demanding aromatic compounds to form atropisomeric biaryl species.

Published
2001

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