1. Metabonomics in patients with atherosclerotic artery disease
- Author
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Emanuele Ferrero, Michelangelo Ferri, Pierangela Giustetto, Jasjit S. Suri, William Liboni, Filippo Molinari, Franco Nessi, and Andrea Viazzo
- Subjects
endarterectomy ,business.industry ,carotid artery ,principal component analysis ,Carotid arteries ,Metabonomics ,stenting ,hematochemical data ,plaque ,atherosclerosis ,discriminant analysis ,partial least squares ,Disease ,Bioinformatics ,Metabolomics ,Medicine ,In patient ,business - Abstract
Atherosclerosis can be thought of as a complex process involving many aspects of the patient’s life, ranging from sex, age, and genetics to lifestyle and nutrition. In the last 10 years, there has been a wide expansion of the “-omics” sciences. Such sciences have proven very effective and accurate in the analysis of complex systems, where the analysis of many factors might help a better understanding of the system itself. Among all the “-omics” sciences, metabolomic and metabonomic are gaining increasing interest. Metabonomics quantitatively measures living systems undergoing the effects of diseases. Unlike genomics and proteomics, metabonomics focuses on the multiparameter evaluation of a living complex system by studying its overall physiological profile. Metabonomics can be thought of as a multiparameter profiling technique of each individual.
- Published
- 2011