1. Cardiovascular risk and stroke mortality in persons living with HIV: a longitudinal study in a hospital in Yaounde.
- Author
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Kuate LM, Tchuisseu LAK, Jingi AM, Kouanfack C, Endomba FT, Ouankou CN, Ngarka L, Noubiap JJ, Kingue S, Menanga A, and Zogo PO
- Subjects
- Adult, Aged, Anti-HIV Agents administration & dosage, Cameroon, Cohort Studies, Female, HIV Infections drug therapy, Heart Disease Risk Factors, Humans, Ischemic Stroke epidemiology, Ischemic Stroke mortality, Length of Stay, Longitudinal Studies, Male, Middle Aged, Retrospective Studies, Risk Factors, Stroke mortality, Cardiovascular Diseases epidemiology, HIV Infections epidemiology, Hospitalization statistics & numerical data, Stroke epidemiology
- Abstract
Introduction: HIV infection is a well-known risk factor for stroke, especially in young adults. In Cameroon, there is a death of data on the outcome of stroke among persons living with HIV (PLWH). This study aimed to assess the cardiovascular risk profile and mortality in PLWH who had a stroke., Methods: this was a retrospective cohort study of all PLWH aged ≥18 years admitted for stroke between January 2010 and December 2019 to the Cardiology Unit of the Yaoundé Central Hospital, Cameroon. Cardiovascular risk was estimated using the modified Framingham score, with subsequent dichotomization into low and intermediate/high risk. Mortality was assessed on day 7 during hospitalization (medical records), at one month, and one year by telephone call to a relative., Results: a total of 43 PLWH who had a stroke were enrolled. Their mean age was 52.1 (standard deviation 12.9) years, most of them were female (69.8%, n = 30). There were 25 (58.1%) patients on concomitant antiretroviral therapy. The Framingham cardiovascular risk score at admission was low in 29 patients (67.4%) and intermediate to high in 14 patients (32.6%). Ischemic stroke was the most common type of stroke in 36 persons (83.7%). The length of hospital stay was 11.4 (interquartile range 9.2-13.7) days. Mortality at 1 year was 46.5% (n = 20)., Conclusion: stroke mortality was high in this population of PLWH. Most patients had a low Framingham score, suggesting that this risk estimation tool underestimates cardiovascular risk in PLWH., Competing Interests: The authors declared no competing interests., (Copyright: Liliane Mfeukeu Kuate et al.)
- Published
- 2021
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