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COVID-19 sequelae are varied, and whether they are temporary or permanent is still unknown. Identifying these sequelae may guide therapeutic strategies to improve these individuals' recovery. This prospective cohort aimed to assess body composition, cardiopulmonary fitness, and long-term symptoms of overweight individuals affected by COVID-19. Participants (n = 90) were divided into three groups according to the severity of acute COVID-19: mild (no hospitalization), moderate (hospitalization, without oxygen support), and severe/critical cases (hospitalized in Intensive Care Unit). We assessed body composition with a tetrapolar multifrequency bioimpedance, hemodynamic variables (heart rate, blood pressure, and peripheral oxygen saturation-SpO 2 ) at rest, and the Bruce test with direct gas exchange. Two assessments with a one-year interval were performed. The most prevalent long-term symptoms were memory deficit (66.7%), lack of concentration (51.7%), fatigue (65.6%), and dyspnea (40%). Bruce test presented a time effect with an increase in the distance walked after 1 year just for severe/critical group (p < 0.05). SpO 2 was significantly lower in the severe/critical group up to 5 min after the Bruce test when compared to the mild group, and diastolic blood pressure at the end of the Bruce test was significantly higher in the severe/critical group when compared to mild group (p < 0.05; for all comparisons). A time effect was observed for body composition, with increased lean mass, skeletal muscle mass, fat-free mass, and lean mass just for the severe/critical group after 1 year (p < 0.05). Cardiopulmonary fitness parameters did not differ among the groups, except for respiratory quotient with higher values for the severe/critical group when compared to itself after 1 year. All COVID-19 patients might present long-term sequelae, regardless of the acute disease severity. Reassessing and identifying the most prevalent long-term sequelae are essential to perform more precise health promotion interventions., (© 2023. Springer Nature Limited.)

This study aimed to evaluate the effect and individual responsiveness after 12 weeks of high-intensity interval training (HIIT) and moderate-intensity of continuous training (MICT) on adiponectin, cardiometabolic risk factors and physical fitness in overweight adolescents. This study was participated by 52 adolescents, both sexes, 11 and 16 years old, separated into HIIT (n = 13), MICT (n = 15), and control group (CG, n = 24). Body mass, height, waist circumference (WC), fat mass (FM), fat-free mass (FFM), blood pressure, high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c), triglycerides, glucose, insulin, adiponectin, and C-reactive protein (CRP) were evaluated. Body mass index z-score (BMI-z), waist-to-height ratio (WHtR), insulin resistance, and insulin sensitivity were calculated. Resting heart rate (HR rest ), peak oxygen consumption (VO 2peak ), right handgrip strength (HGS-right), left handgrip strength (HGS-left), and abdominal resistance (ABD) was evaluated. HIIT session lasted around 35 min and MICT of 60 min of exercises on stationary bicycle, three times a weekday for 12 weeks. ANOVA, effect size, and prevalence of responders were used for statistical analysis. HIIT reduced BMI-z, WHtR, LDL-c, and CRP, while increased of physical fitness. MICT reduced HDL-c, while increased of physical fitness. CG reduced FM, HDL-c, and CRP, while increased FFM and HR rest . Frequencies of respondents in HIIT were observed for CRP, VO 2peak , HGS-right, and HGS-left. Frequencies of respondents in MICT were observed for CRP and HGS-right. Frequencies of no-respondents in CG were observed for WC, WHtR, CRP, HR rest , and ABD.  Conclusion: Interventions with exercises were effective to adiposity, metabolic health, and physical fitness improvements. Individual responses were observed in inflammatory process and physical fitness, important changes in overweight adolescent's therapy.  Trial registration number and date of registration: This study was registered with the Brazilian Registry of Clinical Trials (REBEC), the number RBR-6343y7, date of registration May 3, 2017. What is Known: • Effect of regular physical exercise positively affects overweight, comorbidities, and metabolic diseases, recommended mainly for children and adolescents. What is New: • Due to the great inter-individual variability, the same stimulus can provide different responses; adolescents who benefit from the stimulus are considered responsive. • Intervention of HIIT and MICT did not alter the concentrations of adiponectin; however, the adolescents presented responsiveness to the inflammatory process and physical fitness., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

There are only a few studies that have examined the interaction between physical activity (PA), cardiorespiratory fitness (CRF), and overweightness/obesity in adolescents, and these studies have shown some limitations. The objective of this study was to examine whether the association between PA (moderate-vigorous PA [MVPA], moderate PA [MPA], and vigorous PA [VPA]) and obesity is mediated by CRF. This cross-sectional study was conducted in six middle and high-schools in the Porto district (Portugal), comprising 632 children and adolescents. Fat mass (FM), CRF, MVPA, MPA, and VPA were assessed. The Process macro for SPSS was used. CRF was significantly associated with PA for both children and adolescents. Likewise, FM was negatively and significantly associated with CRF for both children (β = -0.337) and adolescents (β = -0.255). FM was associated with PA in children (MVPA: β = -0.102; MPA: β = -0.118; VPA: β = -0.305) and adolescents (MVPA: β: -0.103; MPA: β = -0.082; VPA: β = -0.204). The mediation analysis showed that the association between PA (MVPA//MPA/VPA) and obesity was mediated by CRF, in both children and adolescents, with a significant value in the Sobel test. Obesity is associated with CRF and MVPA, MPA, and VPA. However, CRF acted as a complete mediator between the association of obesity and PA.

Background: A better understanding of how cardiorespiratory fitness (CRF) and adiposity interact to associate with arterial blood pressure over time remains inconclusive. Thus, the aim of the present study was to examine whether changes in CRF moderates the association between body fat percentage (BF%) and arterial blood pressure in children and adolescents., Methods: This is an observational longitudinal study with 407 children and adolescents aged 8-17 years followed-up for three years from a city in Southern Brazil. Participants were evaluated in 2011 and 2014. CRF was measured by validated field-based tests following the Projeto Esporte Brazil protocols and peak oxygen uptake (VO 2peak ) was estimated. BF% was determined by the measures of tricipital and subscapular skinfolds using equations according to sex. Systolic and diastolic blood pressure (SBP, DBP) were measured with a sphygmomanometer according to standard procedures. Moderation analyses included multiple linear regression models adjusted for sex, age, pubertal status, height, socioeconomic level, skin color, and the arterial blood pressure variable itself at baseline., Results: It was observed a significant inverse association between VO 2peak at baseline with SBP (β = - 0.646 CI95% = - 0.976  - 0.316) and DBP (β = - 0.649 CI95% = - 0.923  - 0.375) at follow-up and a positive association between BF% at baseline with SBP (β = 0.274; CI95% = 0.094 0.455) and DBP (β = 0.301; CI95% = 0.150 0.453) at follow-up. In addition, results indicated a significant interaction term between changes in VO 2peak and BF% at baseline with both SBP (p = 0.034) and DBP at follow-up (p = 0.011), indicating that an increase of at least 0.35 mL/kg/min and 1.78 mL/kg/min in VO 2peak attenuated the positive relationship between BF% with SBP and DBP., Conclusion: CRF moderates the relationship between BF% and SBP and DBP in children and adolescents., (© 2022. The Author(s).)

Introduction: This study aims to investigate the individual and combined associations of physical activity, sedentary time, diet, and sleep at baseline on cardiorespiratory fitness at 24-month follow-up in adolescents., Methods: The DADOS (Deporte, ADOlescencia y Salud) prospective cohort study was performed between 2015 and 2017. Analyses were conducted in 2020 and included 189 adolescents aged 13.9 (SD=0.3) years at baseline. Vigorous physical activity, total sedentary time, and sleep duration were evaluated by GENEActiv accelerometer. Sleep quality and adherence to a Mediterranean diet were evaluated by questionnaires. Cardiorespiratory fitness was assessed by the 20-meter shuttle run test. A healthy lifestyle index was created by including positive scores for each individual behavior, and 3 categories of achievement (≤1, 2, ≥3) were established., Results: Performing high vigorous physical activity and low screen time at baseline were individually associated with the likelihood of achieving high cardiorespiratory fitness at follow-up (OR=3.33 and 3.09, respectively). ANCOVA indicated that adolescents with a healthy lifestyle index ≥3 at baseline showed higher cardiorespiratory fitness at follow-up than those with a healthy lifestyle index of 2 and ≤1 (74.4 [SE=1.5] vs 68.9 [SE=1.4] and 67.8 [SE=1.5] laps, respectively; p<0.01). Adolescents with a healthy lifestyle index ≥3 at baseline were more likely to have high cardiorespiratory fitness at follow-up (OR=3.10) than their peers with ≤1., Conclusions: The results showed a cumulative impact of baseline health-related behaviors on cardiorespiratory fitness at 24-month follow-up in adolescents. These findings underline the key role of promoting a healthy lifestyle to improve adolescents' health., (Copyright © 2021 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.)

Purpose: Recently, doubts have been raised concerning the validity of the 20-m shuttle run test (20mSRT) to predict cardiorespiratory fitness (CRF) in youth. Despite these doubts, authors continue to provide powerful evidence that CRF can be predicted reliably using the 20mSRT albeit using contrasting models. Therefore, we aimed to compare a new linear model with an alternative allometric model to predict CRF (peak oxygen uptake, V˙O2peak) using the 20mSRT., Methods: The study included 148 adolescents (43% girls) age 13.37 ± 1.84 yr. Adolescents were randomly assigned to validation (n = 91) and cross-validation (n = 57) groups. V˙O2peak was measured using a gas analyzer in both maximal exercise tests in the laboratory and the 20mSRT. Multiple linear regression methods were applied to develop the linear models using the 20mSRT (laps), body mass index, and body fat percentage. Alternative allometric models were also proposed/fitted using the 20mSRT (laps), height, and body mass., Results: The criterion validity values of both the linear and the allomeric models were found to be acceptable, with R2 = 82.5% and 82.7% respectively, providing reassuring evidence that the 20mSRT can be used with confidence to predict CRF. However, the allometric model identified a height-to-mass ratio, not dissimilar to the inverse body mass index (known to be a measure of leanness), to be associated with CRF. The allometric model also revealed that the rise in energy cost (V˙O2peak) with increasing laps was exponential. This will more accurately reflect the nonlinear rise in energy demand of shuttle running as the test progresses to exhaustion., Conclusions: These observations provided powerful evidence that allometric models are more than satisfactory in terms of both criterion and construct validity when predicting CRF (V˙O2peak) using the 20mSRT., (Copyright © 2021 by the American College of Sports Medicine.)

Objectives: To analyse the prevalence and association between metabolic syndrome (MetS), clustered cardiometabolic risk (CCMR), obesity (body mass index [BMI], fat mass [FM] and waist circumference [WC]), and cardiorespiratory fitness (CRF); and to assess whether obesity (BMI, FM, and WC) acts as a mediator between CRF and MetS or CCMR., Methods: This cross-sectional study included a subsample of the AFINA-te Study (n = 209; 11.51 ± 0.72 years old). BMI, FM, and WC were assessed. The Course-Navette test was used to assess CRF. MetS was calculated following the International Diabetes Federation (IDF) definitions, and assessed using WC, triglycerides (TGs), high density lipoprotein (HD), fasting glucose (FG), and systolic and diastolic blood pressures (SBP/DBP). CCMR was calculated based on the sex and age-specific z score., Results: The prevalence of overweightness, obesity, MetS, and CCMR were 17.22, 1.44, 5.74, and 18.36%, respectively. After including BMI, FM, or WC into the model, the association between CRF and MetS was no longer significant, and the association between CRF and CCMR was only significant when it was mediated by BMI (β = -0.006; p = 0.026). The rest of the analysis of the mediation did not show a direct effect, although a significant indirect effect with a significant value for the Sobel test was observed (all p < 0.001)., Conclusions: BMI, FM, and WC act as full mediators in the association between CRF and MetS; FM and WC act as full mediators in the association between CRF and CCMR; and BMI acts as a partial mediator. The use of FM or WC as obesity variables is recommended., (© 2021 Walter de Gruyter GmbH, Berlin/Boston.)

Background: There is a lack of clarity as to which obesity parameters may be more important in the association between cardiorespiratory fitness (CRF) and cardiometabolic risk factors (CMRF)., Aim: To verify the mediating role of different obesity parameters on the association between CRF and CMRF in normal weight and overweight/obese children and adolescents., Methods: This cross-sectional study comprised 999 children and adolescents (534 boys) aged 7-14 years from the south of Brazil. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and percentage of body fat were assessed. Participants were classified as normal weight, overweight and obese according to BMI. CRF was evaluated by the 6-minute run/walk test. . A continuous CMRF score was calculated by summing the Z-scores of the following variables: systolic and diastolic blood pressure, glucose, total cholesterol, high-density lipoprotein cholesterol and triglycerides. Data analysis was performed using partial correlation and linear regression models., Results: BMI, WC, WHtR and percentage of body fat mediated the relationship between CRF and CMRF in overweight/obese boys and girls but not those of normal weight. Additionally, the percentage of the influence of each obesity parameter was 20% for BMI and WC, 16% for percentage of body fat and 18% for WHtR in girls. For boys, the mediation effect was 25% for BMI, 26% for WC, 28% for percentage of body fat and 25% for WHtR., Conclusion: Adiposity plays a central role in CMRF; therefore, maintaining an adequate weight status should be an important objective of health-promoting programmes in early age., Abbreviations : CMRF, cardiometabolic risk factors; CRF, cardiorespiratory fitness; BMI. body mass index; HDL-c, high-density lipoprotein cholesterol, PROCESS PROESP-Br, Projeto Esporte Brasil; SPSS, Package for Social Sciences; TC, total cholesterol; TG, triglycerides; WC, waist circumference; WHtR, waist-to-height ratio; %BF, percentage of body fat.

Background: The aim of this prospective cohort study was to examine whether the association between the cardiorespiratory fitness (CRF) at baseline and blood pressure (BP) at follow-up is mediated by adiposity in adolescents., Materials and Methods: The sample comprised 734 adolescents (349 girls) aged 12-18 years from the LabMed Physical Activity Cohort Study. The variables of interest were measured in 2011 (baseline) and in 2013 (2-year follow-up). CRF was assessed by the 20-m shuttle run test. Body mass index, waist circumference, body fat percentage, pubertal status and resting BP were assessed according to standard procedures. Boot-strapped mediation procedures were performed, and indirect effects (IE) with confidence intervals (CI) not including zero were considered statistically significant., Results: After adjusting for potential confounders, body mass index acted as a mediator of the relationship between CRF and systolic BP (IE = -0. 023; CI = -0.039; -0.009), pulse pressure (IE = -0.023; CI = -0.034; -0.012) and rate product pressure (IE = -2.839; CI = -5.329; -0.340). Similar results were obtained for waist circumference as mediator for systolic BP (IE = -0.019; CI = -0.033; -0.005), pulse pressure (IE = -0.017; CI = -0.028; -0.007) and rate product pressure (IE = -3.793; CI = -6.097; -1.689). Likewise, body fat percentage mediated the association for: systolic BP (IE = -0.029; CI = -0.048; -0.010), pulse pressure (IE = -0.027; CI = -0.041; -0.013) and rate product pressure (IE = -4.280; CI = -7.488; -1.264)., Conclusions: Adiposity mediated the association between CRF and BP in adolescents. Therefore, both optimal CRF and adiposity levels are important to maintain normal BP ranges throughout adolescence., (© 2020 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.)

This study aimed to develop new prediction models from directly determined peak of oxygen uptake (VO 2peak ) in adolescents using 20-metre shuttle run test (20 m-SR) and to compare the new models with previously published equations. This study included 148 adolescents (43% girls), aged 13.37 ± 1.84 years old. Adolescents were randomly assigned to validation (n = 91) and cross-validation (n = 57) groups. VO 2peak was measured using a gas analyser in both maximal exercise tests in the laboratory as well as by 20 m-SR. The multiple linear regression method was applied to develop the models using BMI, BMI-z score and body fat percentage (%FM). The proposed models presented better predictive performance (R2 = 75.6% to 78.9%) and a lower absolute percentage error (%error = 10.51 to 11.78%) than the previously published equations (R2 = 38.8% to 69.1%; %error = 13.13% to 21.54%). The Model with BMI-z was the best fit equation in girls, and the model with BMI-z and %FM in boys. Therefore, it is recommended that the equations developed in the present study be used in future research and projects in the school environment to estimate VO 2peak in adolescents by the 20 m-SR test.

Background: To explore the associations between birth weight and body mass index (BMI) from 6 months to 6 years of age, with cardiorespiratory fitness (CRF), physical activity, and sedentary time in adolescence., Methods: Retrospective school-based study with 539 adolescents (292 girls), mean age of 13.94 (1.62) years. Anthropometric data from birth up to 6 years were extracted from individual child health booklets. CRF was estimated by 20-m shuttle run test. Physical activity and sedentary time were assessed with accelerometers., Results: Birth weight was not associated with any outcome measured in adolescence. From the age of 6 months onwards in girls, and from 3 years in boys, BMI associated inversely with CRF in adolescence. In girls, BMI (at 12 mo and at 3 y of age) associated positively with sedentary time in adolescence, but not with physical activity. In boys, positive associations between BMI at the ages of 3, 5, and 6 years old and time spent in some intensities of physical activity in adolescence were found., Conclusions: BMI during the early years was negatively associated with CRF in adolescence, in a consistent way, for both genders, but with physical activity and sedentary time the associations were scarce and inconsistent, depending on the gender.

The aim was to examine the bidirectional association between cardiorespiratory fitness (CRF) and fatness in a 2-year longitudinal study conducted in young people. A total of 1082 children (512 females) and 727 adolescents (342 females) with complete data at baseline and follow-up were included. CRF was determined by the 20-m shuttle run test. Height and weight were measured, and body mass index and fat mass index (kg/m 2 ) were calculated. Triceps and subscapular skinfolds were assessed to compute body fat percentage. Bidirectionality was tested by including CRF and each fatness index as exposures and outcomes, alternatively, in different regression models. CRF was prospectively associated with fatness index levels (ß from -0.186 to -0.528; P < .001), remaining significant in children after adjusting for baseline fatness indices. Fatness indices were prospectively associated with CRF (ß from -0.207 to -0.479; P < .001), with no substantial changes observed in children and female adolescents when baseline CRF was considered. Changes in CRF were prospectively associated with several fatness indices, regardless of body fatness at baseline (ß from -0.062 to -0.220; P < .05). Body fatness changes were associated with future CRF levels, independently of baseline CRF, especially in children of both sexes and male adolescents (ß from -0.079 to -0.260; P < .05). Overall, a bidirectional association was observed between CRF and fatness in children and adolescents. The attainment of optimal CRF and fatness levels in early ages should be promoted since it could result in favorable future fatness and CRF levels, respectively, which are two key determinants of health status., (© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Results from several studies show that only obese, unfit subjects, but not obese, fit subjects, are at higher mortality risk than are normal-weight fit subjects. The aim of the study was two-fold: (1) to examine the differences in C-reactive protein levels across different metabolic phenotypes (healthy and unhealthy) of weight status and (2) ascertain whether high levels of cardiorespiratory fitness (CRF) attenuate the association of C-reactive protein and metabolic phenotypes of weight status. This was a pooled study, which included data from three cross-sectional projects (1706 youth (921 girls) aged 12-18 years). We used a Shuttle run test to assess CRF. Adolescents were classified into six metabolic phenotypes (healthy and unhealthy) of weight status (non-overweight, overweight and obese), based on age- and sex-specific cutoff points for triglycerides, systolic blood pressure, HDL-cholesterol, glucose and body mass index. High-sensitivity assays were used to obtain the C-reactive protein as inflammatory biomarker. After adjustment for potential confounders (age, sex, pubertal stage and country), the analysis of covariance (ANCOVA) shows that C-reactive protein is directly associated with metabolic phenotypes of weight status. Subjects with obesity, regardless of their metabolic profile, had higher levels of C-reactive protein Z-score. In addition, (after adjustments for potential confounders) a two-way ANCOVA showed that high levels of CRF attenuated the associations of C-reactive protein levels in metabolic healthy non-overweight and in adolescents with obesity. In conclusion, higher CRF levels may attenuate the detrimental association between obesity and C-reactive protein independently of metabolic phenotype. Findings from this study are important for prevention, clinical practice on issues associated with adiposity and metabolic disorders., Competing Interests: The authors declare no conflict of interest.

Background: The combination of interval training and resistance training has showed interesting results in chronic heart failure patients, corroborating the benefits of physiological adaptations of both protocols., Objective: To evaluate the effect of the combination of interval training and resistance training program when compared to interval training alone and/or without intervention group on cardiorespiratory fitness in patients with chronic heart failure., Methods: We search MEDLINE via PubMed, ScienceDirect, Sportdiscus, BIREME and Scielo, from their inception to December 2018. Were included both randomized and non-randomized controlled trials comparing the effect of combined training, interval training alone and/or WI group on VO 2peak (expressed in ml/kg/min), in people with chronic heart failure patients. The meta-analysis was conducted via Review Manager v 5.3 software, using random effect model., Results: Ten articles were selected (nine randomized controlled trial), involving 401 participants. Six studies compared combined training with interval training and six studies compared combined training with the without intervention group. Eighty percent of the trials presented moderate risk of bias and twenty percent low risk of bias. Data showed significant difference and major increase in VO 2peak in favor to combined training group compared to interval training group (SMD=0.25; CI=0.04-0.46) and without intervention group (SMD=0.46; CI=0.29-0.64), respectively., Conclusion: The combination of interval training and resistance training showed more effective in increasing cardiorespiratory fitness in patients with heart failure than interval training alone and non-exercise therapy. However, further studies should be conducted to increase the understanding of this combined training method., (Copyright © 2019 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier Editora Ltda. All rights reserved.)

We sought (i) to evaluate the associations of cardiorespiratory fitness (CRF), muscular fitness (MF) and Southern European Atlantic Diet (SEADiet) with atherogenic index of plasma (AIP) and (ii) to investigate de combined association of MF, CRF and SEADiet on AIP in adolescents. A cross-sectional school-based study was conducted on 493 adolescents (285 girls and 208 boys) aged 15-18 years, from the Portuguese Azorean Archipelago. CRF was measured by shuttle run test and MF by curl up and push up tests. Adherence to SEADiet was assessed with a semi-quantitative food frequency questionnaire (FFQ). The AIP was estimated as log (TG/HDL-C). Measures of pubertal stage and socioeconomic status were assessed. Linear regression showed a significant inverse association between MF (standardized β = -0.165; p < 0.001), CRF (standardized β = -0.081; p < 0.030) and SEADiet (standardized β = -0.081; p < 0.045) with AIP, after adjustments for age, sex, pubertal stage and parental education. Furthermore, participants classified with an optimal as well as those with low adherence to a SEADiet but with LowMF/LowCRF had on average the highest AIP (F(7.482) = 3.270; p = 0.002). Moreover, optimal SEADiet with HighMF/HighCRF group showed the lowest AIP when compared with those with low adherence to a SEADiet with HighMF/HighCRF group (p = 0.03). AIP is inversely associated with MF, CRF and SEADiet. The low MF combined with a low CRF levels seems to overcome the potential healthy effect of having an optimal adherence to the SEADiet on AIP. However, an optimal adherence to SEADiet seems to improve the AIP in those adolescents with high fitness levels.

Objective: The purpose of this study was to examine the longitudinal associations between cardiorespiratory fitness and health-related quality of life (HRQoL) in a sample of adolescents, and to determine whether changes in cardiorespiratory fitness were associated with HRQoL over a 2-year follow-up., Methods: This is a longitudinal analysis with 571 Portuguese adolescents (274 boys and 297 girls) aged 12-18 years. HRQoL was measured with the Kidscreen-10 questionnaire; the 20 m shuttle-run was used to estimate cardiorespiratory fitness; socioeconomic status was assessed with the Family Affluence Scale; and pubertal stage was assessed with Tanner stages. Linear regression and analysis of covariance (ancovas) were used to examine the associations between cardiorespiratory fitness and HRQoL., Results: HRQoL decreased over a 2-year period both in boys and girls (P < .05). Moreover, girls at baseline and at follow-up reported significantly lower HRQoL values than boys (between subjects P < .001). After adjustments for potential confounders, regression analyses showed significant cross-sectional associations between cardiorespiratory fitness and HRQoL both at baseline (B = 0.095; P = .023) and at follow-up (B = 0.090; P = .012). ancova showed that adolescents whose cardiorespiratory fitness decreased over time exhibited lower scores of HRQoL at follow-up, compared to those with persistent high cardiorespiratory fitness; this held after adjustments for age, sex, socioeconomic status, and pubertal stage., Conclusions: Changes in cardiorespiratory fitness during adolescence were associated with HRQoL over a 2-year period. This study suggests that improving cardiorespiratory fitness could be an important strategy in improving the HRQoL of adolescents., (© 2019 Wiley Periodicals, Inc.)

Purpose: Low-grade inflammation leads to several metabolic disorders, and adherence to a Mediterranean diet (MedDiet), cardiorespiratory fitness (CRF), and muscular fitness (MF) has been considered important markers of metabolic healthy in youth. We investigated the combined association of adherence to Mediterranean diet, and muscular and cardiorespiratory fitness on high-sensitivity C-reactive protein (hs-CRP) in adolescents., Methods: This is a cross-sectional analysis with 1462 adolescents (625 girls) aged 9-18 years from Colombia and Portugal. MedDiet was assessed by Kidmed questionnaire. Shuttle run test was used to assess CRF. MF was assessed by the standing long-jump and handgrip tests. High-sensitivity assays were used to obtain the hs-CRP level., Results: Logistic regression shows that subjects with a low adherence to MedDiet and LowMF/LowCRF had a similar odds (OR = 2.3; 95% CI 1.2-4.0) as those with an optimal adherence to MedDiet and LowMF/LowCRF (OR = 2.3; 95% CI 1.2-5.0) of expressing high inflammatory profile when compared to those with an optimal adherence to MedDiet and HighMF/HighCRF. In addition, ANCOVA showed that subjects classified as high adherence to MedDiet and HighMF/HighCRF had, on average, the lowest levels of hs-CRP (F (7,1454)  = 2.051 p = 0.04)., Conclusion: The combination of optimal levels of CRF and MF and adherence to MedDiet is associated with lower hs-CRP. However, high MF and CRF seems to counteract the deleterious effect of having a low adherence to the MedDiet on hs-CRP levels.

Background Cardiorespiratory fitness (CRF) and pubertal stages have been related to many health outcomes, including obesity and adipocytokines. Thus, the present study aimed to analyze the moderator role of CRF and pubertal stage in the relationship between adiposity and adipocytokines in girls. Method This cross-sectional study was performed with 42 pre-pubertal girls aged from 7 to 11 years and 54 post-pubertal girls aged from 13 to 17 years. Blood samples were collected to determine the serum levels of leptin and adiponectin, and then the leptin/adiponectin ratio (L/A ratio) was calculated. CRF, anthropometric and body composition indicators were assessed. For statistical analysis, descriptive statistics and several linear regression models were used. The moderation analysis was tested using the PROCESS macro. Results An interaction between body mass index (BMI) and CRF (β: -0.70; confidence interval [CI]: -1.29, -0.12), as well as between BMI and pubertal stage (β: 0.79; CI: 0.28, 1.30) with leptin, was found. Regarding the L/A ratio, an interaction was found only in BMI × CRF (β: -0.56; CI: -1.06, -0.06). Using a combined interaction (CRF and pubertal stage), the results showed a positive association between BMI with leptin and L/A ratio only in low CRF, pre-pubertal and post-pubertal stages. Conclusion This study suggests a protective role of high levels of CRF in the relationship between BMI and adipocytokines. Despite the effect of pubertal stage, the results suggest that youth should be engaged in physical activity in order to improve CRF levels and consequently improve cardiometabolic health.

Objective: To determine the ability of 8 different maximal oxygen uptake (VO 2max ) equations to discriminate between low and high cardiometabolic risk, and to determine cardiorespiratory fitness (CRF) cutoffs associated with a more favorable cardiometabolic risk profile in Colombian children and adolescents., Study Design: In a cross-sectional study, CRF was estimated using the 20-m shuttle run test in 2870 schoolchildren (54.5% girls) from Bogota, Colombia. We computed a metabolic syndrome score (MetScore) as the sum of the age- and sex-standardized scores of waist circumference, triglycerides, high-density lipoprotein cholesterol, glucose, and systolic and diastolic blood pressure., Results: Linear regression analyses showed that the Barnett et al (b) and Mahar equations were negatively associated with MetScore, showing the highest discriminatory accuracy for identifying the low/high cardiometabolic risk in both sexes and both age groups (9-12 years and 13-17 years)., Conclusions: We propose that the Barnett et al (b) equation for boys and girls, VO 2max  = 25.8 × (6.6 × G × 0.2 × (body mass + 3.2 × (final speed))), where G is gender (male = 0; female = 1), be used to classify youths at metabolic risk. The CRF cutoffs can serve as a quantitative marker of a healthier cardiovascular profile in Colombian children and adolescents., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Objectives: To examine the association between cardiorespiratory fitness and cardiovascular indices 2 years later, and to determine whether changes in cardiorespiratory fitness are associated with cardiovascular indices at a 2-year follow-up in adolescents., Study Design: The sample comprised 734 adolescents (349 girls) aged 12-18 years followed for 3 years from the LabMed Physical Activity Study. Cardiorespiratory fitness was assessed by the 20-meter shuttle run test. Height, weight, waist circumference, and resting blood pressure (BP) were measured according to standard procedures., Results: Regression analyses showed a significant inverse association between cardiorespiratory fitness at baseline and systolic BP (B = -0.126; P = .047) and rate pressure product (B = -29.94; P = .016), at follow-up after adjustments for age, sex, height, pubertal stage, socioeconomic status, and waist circumference. Significant differences were found between cardiorespiratory fitness groups (fit vs unfit) at baseline and systolic BP and rate pressure product at follow-up (P < .05 for all). Analysis of covariance showed a significant association between cardiorespiratory fitness changes and systolic BP (P = .024) and rate pressure product (P = .014), after adjustment for age, sex, height, pubertal status, socioeconomic status, and waist circumference., Conclusions: Changes in cardiorespiratory fitness during adolescence were associated with cardiovascular indices over a 2-year period. Adolescents with persistently low levels of cardiorespiratory fitness exhibited the highest levels of systolic BP and rate pressure product., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Purpose: We investigated the combined effect of cardiorespiratory fitness and the clustered score of inflammatory biomarkers (InflaScore) on the cardiometabolic risk score in adolescents., Methods: This is a cross-sectional analysis with 529 adolescents (267 girls) aged 12-18 years. The shuttle run test was used to assess cardiorespiratory fitness. Continuous scores of clustered inflammatory biomarkers (high sensitivity C-reactive protein, complement factors C3 and C4, fibrinogen and leptin); cardiometabolic risk score (systolic blood pressure, triglycerides, ratio total cholesterol/HDL, HOMA-IR and waist circumference) were computed., Results: Adolescents with a higher inflammatory profile had the highest cardiometabolic risk score; adolescents with high InflaScore and low fitness had the highest odds of having a high cardiometabolic risk (OR 16.5; 95% CI 7.8-34.5), followed by adolescents with a higher InflaScore but fit (OR 7.5; 95% CI 3.7-8.4), and then by adolescents with a low InflaScore and unfit (OR 3.7; 95% CI 1.6-8.4) when compared to those with low InflaScore and fit, after adjustments for age, sex, pubertal stage, adherence to a Mediterranean dietary pattern and socioeconomic status., Conclusions: The findings of our study suggest that the combination of high inflammatory state and low cardiorespiratory fitness is synergistically associated with a significantly higher cardiometabolic risk score and thus supports the relevance of early targeted interventions to promote physical activity and preservation as part of primordial prevention.

Background: Cardiorespiratory fitness (CRF) and physical activity (PA) seem to have positive effects on academic achievement (AA), although in most studies, objective methods of assessment have not been used., Aim: To examine the associations of CRF and PA with AA., Subjects and Methods: A sample of 640 youngsters (10-18 years) participated in this cross-sectional study. CRF was estimated with the 20-metre shuttle run test and PA was measured using accelerometers. School grades were used to describe AA using mathematics and native language final grades. The relationship between CRF and PA with AA was analysed using ANCOVA., Results: Results show a significant effect of CRF levels on native language grades, after adjustment for confounders [F(3,414) = 3,99 p < 0.05], but not for mathematics [F(3,360) = 0.95 p > 0.05]. No significant effects of PA levels on AA were found., Conclusions: CRF is associated with moderate-to-vigorous PA (MVPA) and higher levels of CRF may influence AA. CRF is positively correlated with MVPA, suggesting that higher amounts of MVPA might improve CRF and indirectly influence AA. Since CRF is dependent on higher intensities of PA, we can suggest a focus on implementing improvement strategies to increase the intensity of physical education lessons.

Purpose: This study examined the independent associations between cardiorespiratory fitness and circulating adiponectin concentration in adolescents, controlling for several potential covariates., Methods: This is a cross-sectional study in Portuguese adolescents. A sample of 529 (267 girls) aged 12-18 years were included and categorized as overweight and nonoverweight. Cardiorespiratory fitness was assessed by 20 meters shuttle run test. We measured serum adiponectin, high-sensitivity C-reactive protein, fasting glucose, insulin and HDL-cholesterol., Results: After adjustment for age, sex, pubertal stage, adherence to the Mediterranean diet, socioeconomic status, body fat percentage, insulin resistance, HDL-cholesterol and C-reactive protein, regression analysis showed a significant inverse association between adiponectin and cardiorespiratory fitness in nonoverweight participants (B=-0.359; p < .042). Analysis of covariance showed a significant difference between the highest cardiorespiratory fitness Healthy zone (above healthy zone) and the Under and the Healthy cardiorespiratory fitness zones in nonoverweight adolescents (p = .03) (F (2, 339) = 3.156, p < .001)., Conclusion: Paradoxically, serum adiponectin levels are inversely associated with cardiorespiratory fitness in nonoverweight, but not in overweight adolescents. In nonoverweight adolescents, those with highest levels of cardiorespiratory fitness (above healthy zone) presented lower levels of adiponectin compared with those in Under and Healthy cardiorespiratory fitness zones.

Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences.

• 2MST is valid and reliable to evaluate cardiorespiratory fitness in older adults. • Distance in the 6MWT present a high correlation with number of steps in the 2MST. • The proposed equation is valid to predict the result for the 6MWT from the 2MST. In healthy older adults, the two-minute step test (2MST) does not have its concurrent validity tested against the six-minute walk test (6MWT), which is a valid cardiorespiratory fitness test frequently applied in geriatric samples. To derive an equation to predict 6MWT from 2MST and to observe the agreement between observed and estimated 6MWT distances. 6MWT and 2MST were measured in 51 older adults (72.9±4.6 years) from community multicomponent exercise programs. Multiple linear regression derives the predictive equation of 6MWT walked distance (dependent outcome) from steps obtained in 2MST, age, sex, and body mass index (independent outcomes). Correlation between 6MWT and 2MST was strong (r=0.696, p<0.001). The regression equation showed good agreement with measured values, when 6MWT was below 600 m. The equation stands as a novel approach to obtaining a valid 6MWT estimation from the 2MST. 2MST is easier and faster, representing an alternative approach when time and space are limited. [ABSTRACT FROM AUTHOR]

Cross-sectional study aimed to analyse differences in cognitive performance across fitness components categories (cardiorespiratory fitness [CRF], speed-agility and muscular fitness [MF]) and weight status in children, and to determine whether physical fitness mediates the association between body mass index (BMI) and cognitive performance. Fitness components and BMI were measured using standard procedures in 630 children aged 5-to-7 years from the provinces of Cuenca and Ciudad Real, Spain. BADyG was used to assess cognitive performance. We used ANCOVA models to test mean differences in cognition scores by BMI and fitness categories. Hayes's PROCESS macro was used for mediation analyses. Children with normal weight scored better in spatial factor and general intelligence than their overweight/obese peers (p < 0.05), but differences were attenuated when controlling for CRF (p > 0.05). Children with better results in CRF and speed-agility scored better in all cognitive dimensions even after controlling for BMI (p < 0.05). Similarly, children with high MF obtained better scores in verbal factor (p < 0.05). All fitness components acted as mediators of the relationship between BMI and general intelligence (p < 0.05). These findings highlight the crucial role of fitness in minimising the negative effect of excess weight on children's cognition. Abbreviations: BMI: Body mass index; CRF: Cardiorespiratory fitness; MF: Muscular fitness; BADyG E1: Battery of general and differential aptitudes; SES: Socioeconomic status; SD: Standard deviation; IE: Indirect effect [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Medicina do Esporte is the property of Redprint Editora Ltda. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Adolescents' physical fitness levels are an important indicator of their lifestyle and seem to have positive consequences in health-related quality of life (HRQoL). The purpose of this study is to analyse the combined associations of cardiorespiratory fitness and muscular fitness with HRQoL and to assess the differences between HRQoL scores across groups of cardiorespiratory fitness and muscular fitness in Portuguese adolescents. This is a cross-sectional analysis with 567 Portuguese adolescents aged 12-18 years-old. HRQoL was measured using the Kidscreen-10 questionnaire. Cardiorespiratory fitness was estimated with the 20-m shuttle-run test. Muscular fitness was evaluated using the handgrip and the standing long jump tests and a muscular fitness index was computed by means of standardized measures of both tests. Socioeconomic status was assessed using the Family Affluence Scale. Body composition (body mass and height) was measured according to standard protocols. Accelerometers were used to obtain objective physical activity time. Pubertal stage was assessed using Tanner stages. Adherence to the Mediterranean diet was assessed using the KIDMED index. Participants were divided into four groups based on low or high values of both cardiorespiratory and muscular fitness. Regression analysis, mediation analysis and ANCOVA were performed. HRQoL was positively associated with cardiorespiratory fitness (B = 0.112; p < 0.05) and muscular fitness score (B = 0.328 p < 0.05), after controlling for potential confounders. However, when both fitness variables were entered in the same model only cardiorespiratory fitness remained significantly associated with HRQoL (B = 0.093 p < 0.05). Cardiorespiratory fitness acted as a full mediator variable on the relationship between muscular fitness and HRQoL in adolescents (p < 0.05). ANCOVA showed that adolescents with high cardiorespiratory fitness/high muscular fitness exhibit better HRQoL scores when compared to those with low muscular fitness/low cardiorespiratory fitness and with those with low muscular fitness/high cardiorespiratory fitness (p < 0.05). In adolescents, the combination of high cardiorespiratory fitness and high muscular fitness was positively associated with a better HRQoL. [ABSTRACT FROM AUTHOR]

Background Physical fitness (PF) and adherence to the Mediterranean diet are important indicators of healthy lifestyles. The purpose of this study is to analyze the independent and combined associations between PF and adherence to Mediterranean diet with health-related quality of life (HRQoL) in adolescents. Methods This is a cross-sectional analysis with 956 Portuguese adolescents aged 12–18 years. HRQoL was measured with the Kidscreen-10 questionnaire. PF was assessed with the ALPHA health-related fitness battery. The 20-m shuttle run test was used for the estimation of cardiorespiratory fitness; handgrip strength and standing long jump tests were applied for the assessment of muscular fitness and the 4 × 10 m shuttle run test for the assessment of motor fitness (speed and agility). The results of the PF tests (cardiorespiratory fitness, muscular fitness and motor fitness) were transformed into standardized values (Z -scores) by age and sex. Adherence to the Mediterranean diet was assessed with the KIDMED index. Regression analysis and analysis of covariance were performed. Results PF (B = 0.228; P < 0.05) and adherence to the Mediterranean diet (B = 0.259; P < 0.05) were positively associated with HRQoL, after controlling for several variables. Participants classified as high PF and high adherence to Mediterranean diet had on average the highest HRQoL score compared with those with low PF and low adherence to Mediterranean diet (F (3, 939) = 4.270; P = 0.005), after adjustments for potential confounders. Conclusions The combination of high PF levels and optimal adherence to Mediterranean diet is positively associated with HRQoL. [ABSTRACT FROM AUTHOR]

Background/objective: In recent years, there has been an increased interest in the associations between physical fitness (PF) and psychosocial aspects of health. This study aimed to analyse the associations between self-reported PF and self-rated health (SRH), life-satisfaction (LS), and quality of life (QoL). Methods: This is a cross-sectional study of 3554 adolescents (1652 boys), aged 13-18, from the HBSC Portuguese survey. PF, health, LS and QoL were self-rated. Results: SRH, LS, and health-related QoL (HRQoL) were significantly and positively correlated with all PF components. From regression model, overall fitness was significantly related with SRH (boys: γ = 0.18, p < 0.001; girls: γ = 0.16, p < 0.001), LS (boys: γ = 0.36, p < 0.001; girls: γ = 0.43, p < 0.001), and HRQoL (boys: γ = 2.26, p < 0.001; girls: γ = 2.54, p < 0.001). Cardiorespiratory fitness was also positively and significantly related with SRH (boys: γ = 0.17, p < 0.001; girls: γ = 0.11, p < 0.001), LS (boys: γ = 0.13, p < 0.05; girls: γ = 0.31, p < 0.001), and HRQoL (boys: γ = 1.74, p < 0.001; girls: γ = 1.57, p < 0.001). Conclusion: These findings suggest that perceived PF is associated with a better SRH, LS, and perceived HRQoL. A few implications regarding public policies were highlighted. [ABSTRACT FROM AUTHOR]

Copyright of Revista da Educação Física/UEM is the property of Universidade Estadual de Maringa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract: There is increasing evidence that cardiorespiratory fitness (CRF) is an important health marker already in youth. This study aimed to determine the ability of five VO2max equations to discriminate between low/high Metabolic Risk in 450 Portuguese adolescents aged 10–18. We measured waist and hip circumferences, fasting glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, and blood pressure. For each of these variables, a Z-score was computed. The HDL-cholesterol was multiplied by −1. A metabolic risk score was constructed by summing the Z scores of all individual risk factors. High risk was considered when the individual had ≥1 SD of this score. Cardiorespiratory fitness (CRF) was measured with the 20-m shuttle run test. We estimated VO2max from the CRF tests using five equations. ROC analyses showed a significant discriminatory accuracy for the Matsuzaka and Barnett(a) equations in identifying the low/high metabolic risk in both genders (Matsuzaka girls: AUC=0.654, 95%CI: 0.591–0.713, p <0.001, VO2max =39.5mLkg−1 min−1; boys: AUC=0.648, 95%CI: 0.576–0.716, p <0.001, VO2max =41.8mLkg−1 min−1; Barnett(a) girls: AUC=0.620, 95%CI: 0.557–0.681, p <0.001, VO2max =46.4mLkg−1 min−1; boys: AUC=0.628, 95%CI: 0.555–0.697, p =0.04, VO2max =42.6mLkg−1 min−1), and the Ruiz equation in boys (AUC=0.638, 95%CI: 0.565–0.706, p <0.001, VO2max =47.1mLkg−1 min−1). The VO2max values found require further testing in other populations as well as in longitudinal studies; the identification of adolescents who have low CRF levels can help detect youth with an increased risk of metabolic disease. [ABSTRACT FROM AUTHOR]

Adolescents' physical fitness levels are an important indicator of their lifestyle and seem to have positive consequences in health-related quality of life (HRQoL). The purpose of this study is to analyse the combined associations of cardiorespiratory fitness and muscular fitness with HRQoL and to assess the differences between HRQoL scores across groups of cardiorespiratory fitness and muscular fitness in Portuguese adolescents. This is a cross-sectional analysis with 567 Portuguese adolescents aged 12-18 years-old. HRQoL was measured using the Kidscreen-10 questionnaire. Cardiorespiratory fitness was estimated with the 20-m shuttle-run test. Muscular fitness was evaluated using the handgrip and the standing long jump tests and a muscular fitness index was computed by means of standardized measures of both tests. Socioeconomic status was assessed using the Family Affluence Scale. Body composition (body mass and height) was measured according to standard protocols. Accelerometers were used to obtain objective physical activity time. Pubertal stage was assessed using Tanner stages. Adherence to the Mediterranean diet was assessed using the KIDMED index. Participants were divided into four groups based on low or high values of both cardiorespiratory and muscular fitness. Regression analysis, mediation analysis and ANCOVA were performed. HRQoL was positively associated with cardiorespiratory fitness (B = 0.112; p < 0.05) and muscular fitness score (B = 0.328 p < 0.05), after controlling for potential confounders. However, when both fitness variables were entered in the same model only cardiorespiratory fitness remained significantly associated with HRQoL (B = 0.093 p < 0.05). Cardiorespiratory fitness acted as a full mediator variable on the relationship between muscular fitness and HRQoL in adolescents (p < 0.05). ANCOVA showed that adolescents with high cardiorespiratory fitness/high muscular fitness exhibit better HRQoL scores when compared to those with low muscular fitness/low cardiorespiratory fitness and with those with low muscular fitness/high cardiorespiratory fitness (p < 0.05). In adolescents, the combination of high cardiorespiratory fitness and high muscular fitness was positively associated with a better HRQoL. [ABSTRACT FROM AUTHOR]

In the present study, we examined different categories of cardiorespiratory fitness and obesity and their relationship with risk of cardiovascular disease (CVD) factors in youth. We hypothesized that youngsters with low cardiorespiratory fitness would be at greater risk of CVD risk factors, whether they are obese or not. This study was carried out as a part of a longitudinal research project conducted in the Porto and Braga districts, Portugal, with children and adolescents aged 10-16 years of age. A total of 392 children (173 boys, 219 girls) participated in the study. We used a chi-square test to analyse the relationship between the participants' cardiorespiratory fitness and body weight (non-overweight or overweight/obese). For the purpose of this study, a new variable with four groups was created: non-overweight +unfit (37.4%), non-overweight + fit (35%), overweight/obese + unfit (11%) and overweight/obese + fit (10%). A one-way analysis of variance was used to compare the differences according to fitness and fatness groups. The main finding of this study was that regardless of fatness, participants with higher cardiorespiratory fitness presented with a lower prevalence of CVD risk factors. [ABSTRACT FROM AUTHOR]

Objective. This study aimed to examine the prospective relationship of baseline body mass index (BMI) and performance in a cardiorespiratory fitness (CRF) field test with a change in BMI (ΔBMI) over a 2-year period in a sample of rural children from elementary school in Fundão, Portugal. Methods. Obesity status was obtained by the age- and sex-specific BMI cut-off points and CRF by a 9-minute run test. Results. BMI stratification at baseline showed that overweight/obese children were over 11 times (OR=11.31; p=0.007) more likely to be ΔBMI gainers than their normal weight peers. Those who were classified as unfit were 3.9 times more likely to be ΔBMI gainers than those classified as fit at baseline. Both BMI at time 1 and CRF change (ΔCRF) were not significantly associated with ΔBMI over time. Conclusion. The findings of this study suggest that children who have higher BMI and lower CRF are likely to have greater BMI gain over time. [ABSTRACT FROM AUTHOR]

We assessed the agreement between maximal oxygen consumption ([Vdot]O2max) measured directly when performing the 20-m shuttle run test and estimated [Vdot]O2max from five different equations (i.e. Barnett, equations a and b; Leger; Matsuzaka; and Ruiz) in youths. The 20-m shuttle run test was performed by 26 girls (mean age 14.6 years, s = 1.5; body mass 57.2 kg, s = 8.9; height 1.60 m, s = 0.06) and 22 boys (age 15.0 years, s = 1.6; body mass 63.5 kg, s = 11.5; height 1.70 m, s = 0.01). The participants wore a portable gas analyser (K4b2, Cosmed) to measure [Vdot]O2 during the test. All the equations significantly underestimated directly measured [Vdot]O2max, except Barnett's (b) equation. The mean difference ranged from 1.3 ml · kg-1 · min-1 (Barnett (b)) to 5.5 ml · kg-1 · min-1 (Leger). The standard error of the estimate ranged from 5.3 ml · kg-1 · min-1 (Ruiz) to 6.5 ml · kg-1 · min-1 (Leger), and the percentage error ranged from 21.2% (Ruiz) to 38.3% (Leger). The accuracy of the equations available to estimate [Vdot]O2max from the 20-m shuttle run test is questionable at the individual level. Furthermore, special attention should be paid when comparisons are made between studies (e.g. population-based studies) using different equations. The results of the present study suggest that Barnett's (b) equation provides the closest agreement with directly measured [Vdot]O2max (cardiorespiratory fitness) in youth. [ABSTRACT FROM AUTHOR]

Background: Metabolic Syndrome (MS) is highly prevalent among obese children with fatty liver. However, it is well-known that there is a lower prevalence of MS in individuals with higher cardiorespiratory fitness (CRF). Aim: To analyse the association between CRF with features of the MS in obese children that present fat liver indicators, namely abnormal alanine aminotransferase (ALT) values. Methods: A total of 79 obese students (40 girls), 10-11 year-olds ( ± 0.60), with abnormal serum ALT from Porto public schools comprised the sample. Measurements included CRF (20-metre Shuttle Run Test), Metabolic Risk Factors (MRF), according to MS International Diabetes Federation criteria, ALT values (Cholestech LDX® analyser) and maturational stage (Tanner criteria). Logistic regression analysis was used to determine the influence of CRF on MRF adjusted for sex, maturation, and BMI. Results: The logistic regression showed that, despite being classified as being obese and presenting abnormal levels of ALT, those classified as fit were less likely to have MS than their unfit counterparts (OR = 0.52; p ≤  0.05). Conclusion: Obese-fit children with abnormal ALT values have a significant reduction in the likelihood to be classified as having MS, even after adjustments for gender, maturation and BMI, Thus, CRF might be an important factor for tackling fatty liver among obese. [ABSTRACT FROM AUTHOR]

Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, and increased PA plays a protective role against NAFLD risk factors, the aim of this study was to analyze the association between PA and a fatty liver marker (alanine aminotransferase - ALT) in obese children and adolescents, independently of central adiposity or CRF. 131 obese children (83 girls, 7-15 year-olds) involved in a PA promotion program comprised the sample. Measurements included anthropometric and body composition evaluations (DEXA), biological measurements (venipuncture), CRF (progressive treadmill test), PA (accelerometry), and maturational stage (Tanner criteria). The associations between ALT with PA intensities, central obesity, and CRF were calculated by three different models of linear regression, adjusted for potential confounders. Level of significance was set at 95%. RESULTS: ALT was negatively associated with MVPA (β = -0.305), and CRF (β = - 0.426), and positively associated with central obesity (β=.468). After adjustment for central obesity the negative and statistically significant association between ALT with MVPA (β = -0.364) and CRF (β = -0.550) still persists while a positive and significantly correlation was shown between ALT and SB (β = 0.382). Additional adjustment for CRF (Model 3) showed significant associations for all the PA intensities analyzed including light activity. PA at different intensities is associated to a fatty liver marker in obese children and adolescents, independently of central adiposity or CRF. [ABSTRACT FROM AUTHOR]

Abstract: Objective: To analyze how modifiable health-related variables are clustered and associated with children's participation in play, active travel and structured exercise and sport among boys and girls. Methods: Data were collected from 9 middle-schools in Porto (Portugal) area. A total of 636 children in the 6th grade (340 girls and 296 boys) with a mean age of 11.64years old participated in the study. Cluster analyses were used to identify patterns of lifestyle and healthy/unhealthy behaviors. Multinomial logistic regression analysis was used to estimate associations between cluster allocation, sedentary time and participation in three different physical activity (PA) contexts: play, active travel, and structured exercise/sport. Results: Four distinct clusters were identified based on four lifestyle risk factors. The most disadvantaged cluster was characterized by high body mass index, low high-density lipoprotein cholesterol and cardiorespiratory fitness and a moderate level of moderate to vigorous PA. Everyday outdoor play (OR=1.85, 95%CI 0.318–0.915) and structured exercise/sport (OR=1.85, 95%CI 0.291–0.990) were associated with healthier lifestyle patterns. There were no significant associations between health patterns and sedentary time or travel mode. Conclusion: Outdoor play and sport/exercise participation seem more important than active travel from school in influencing children's healthy cluster profiles. [Copyright &y& Elsevier]