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Your search keyword '"Michela, Montefiori"' showing total 3 results
Start Over Author "Michela, Montefiori" Topic cardiology and cardiovascular medicine
3 results on '"Michela, Montefiori"'

1. Cognitive functions: evaluation and changes after transcatheter aortic valve implantation in elderly patients

Author

Cristina Ciuca, Nevio Taglieri, Lisa Placuzzi, Antonio Marzocchi, Cinzia Marrozzini, Francesco Saia, Susy Ferrari, Barbara Bordoni, Rabih Chattat, Carolina Moretti, Gianni Dall'Ara, Michela Montefiori, Ciuca, Cristina, Ferrari, Susy, Placuzzi, Lisa, Marrozzini, Cinzia, Taglieri, Nevio, Bordoni, Barbara, Dall'Ara, Gianni, Moretti, Carolina, Montefiori, Michela, Chattat, Rabih, Marzocchi, Antonio, and Saia, Francesco

Subjects
Male, medicine.medical_specialty, Transcatheter aortic, Pilot Projects, 030204 cardiovascular system & hematology, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Cognition, Quality of life, Internal medicine, medicine, Verbal fluency test, Humans, multidimensional, 030212 general & internal medicine, Cognitive impairment, geriatric evaluation, Pathological, transcatheter aortic valve implantation, cognitive impairment, cognitive statu, Aged, Aged, 80 and over, Heart Valve Prosthesis Implantation, Memory Disorders, Mini–Mental State Examination, medicine.diagnostic_test, business.industry, Aortic Valve Stenosis, aortic stenosi, Mental Status and Dementia Tests, Treatment Outcome, quality of life, Mini Mental state examination, Aortic Valve, Cardiology, Molecular Medicine, Female, Verbal memory, Cardiology and Cardiovascular Medicine, business, Cognition Disorders
Abstract

Aim: To assess the prevalence and postprocedural evolution of cognitive impairment (CI) in patients undergoing transcatheter aortic valve implantation. Methods: 62 patients were enrolled. Mini Mental state examination (MMSE), verbal memory test (VMT), visual search test (VST) and phonemic verbal fluency (PVF) were used to evaluate the cognitive status. CI was considered when a pathological result of MMSE was confirmed by VMT, VST and PVF. Results: A total of 26.2% patients had CI at baseline. MMSE, VMT, VST and PVF were pathologic in 39, 16.1, 8.1 and 22.6% of the patients, respectively. Overall, no significant differences in cognitive function in any dimension were observed from baseline up to 1-year follow-up. Conclusion: CI is frequent in patients undergoing transcatheter aortic valve implantation, though the procedure does not forge cognitive status.

Published
2017

2. Predictors of complicated athero-thrombotic lesions in non-ST segment acute coronary syndrome

Author

Laura Alessi, Laura Cinti, Carolina Moretti, Antonio Marzocchi, Claudio Rapezzi, Michela Montefiori, Stefania Rosmini, Tullio Palmerini, Cinzia Marrozzini, Fabio Vagnarelli, Nevio Taglieri, Gianni Dall'Ara, Angelo Branzi, Francesco Saia, Taglieri N, Dall'Ara G, Rapezzi C, Saia F, Cinti L, Rosmini S, Alessi L, Vagnarelli F, Moretti C, Palmerini T, Marrozzini C, Montefiori M, Branzi A, and Marzocchi A.

Subjects
Male, medicine.medical_treatment, Myocardial Infarction, Infarction, Coronary Artery Disease, Kaplan-Meier Estimate, Coronary Angiography, Angina, Recurrence, Risk Factors, Clinical endpoint, Odds Ratio, ST segment, Coronary lesions, Non-ST segment elevation acute coronary syndrome, Aged, 80 and over, Framingham Risk Score, General Medicine, Middle Aged, Risk stratification, Plaque, Atherosclerotic, Cardiology, Disease Progression, Female, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Acute coronary syndrome, ACUTE CORONARY SYNDROMES, angina, Global Registry of Acute Coronary Events, NO, Predictive Value of Tests, Internal medicine, medicine, Humans, Angina, Unstable, Acute Coronary Syndrome, Aged, Retrospective Studies, Chi-Square Distribution, Rupture, Spontaneous, business.industry, Coronary Thrombosis, Percutaneous coronary intervention, Odds ratio, medicine.disease, Logistic Models, Multivariate Analysis, business
Abstract

AIMS: Non-ST segment elevation acute coronary syndrome (NSTE-ACS) is a heterogeneous syndrome in terms of patho-physiological mechanisms and prognosis. We sought to investigate the clinical features associated with complicated athero-thrombotic (CAT) coronary lesions and their prognostic relevance in NSTE-ACS. METHODS: We enrolled 701 consecutive NSTE-ACS patients without previous coronary bypass undergoing coronary angiography. The study population was divided into two groups according to the presence/absence of angiographic signs of endoluminal thrombi and/or plaque rupture, defined as CAT lesions. Multivariable analyses were used to identify predictors of CAT lesions. Their relation to composite endpoint of death, re-myocardial infarction, and re-unstable angina was investigated with the use of multivariable logistic regression. RESULTS: Patients with CAT lesions (n = 279, 40%) had a higher incidence of the combined endpoint (11.5 vs. 4.3%; P

Published
2013

3. Baseline white blood cell count is an independent predictor of long-term cardiovascular mortality in patients with non-ST-segment elevation acute coronary syndrome, but it does not improve the risk classification of the GRACE score

Author

Maria Letizia Bacchi Reggiani, Francesco Saia, Carolina Moretti, Fabio Vagnarelli, Michela Montefiori, Antonio Marzocchi, Laura Cinti, Nevio Taglieri, Stefania Rosmini, Laura Alessi, Tullio Palmerini, Claudio Rapezzi, Paolo Guastaroba, Cinzia Marrozzini, Angelo Branzi, Taglieri N, Bacchi Reggiani ML, Palmerini T, Cinti L, Saia F, Guastaroba P, Marrozzini C, Moretti Carolina, Montefiori M, Rosmini S, Alessi L, Vagnarelli F, Branzi A, Rapezzi C, and Marzocchi A

Subjects
medicine.medical_specialty, Acute coronary syndrome, Cardiovascular mortality, business.industry, Follow up studies, White blood cell count, Global Registry of Acute Coronary Events score, Independent predictor, medicine.disease, NO, medicine.anatomical_structure, White blood cell, Internal medicine, Cardiology, Medicine, ST segment, Pharmacology (medical), In patient, Cardiology and Cardiovascular Medicine, business, Risk classification
Abstract

Objectives: To investigate the prognostic significance of baseline white blood cell count (WBCc) in non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and its additive predictive value beyond the Global Registry of Acute Coronary Events (GRACE) score. Methods: We included 1,315 consecutive NSTE-ACS patients. Patients were divided in quartiles according to the WBCc (cells per 1 mm3) i.e. Q1 Results: The median age of the study population was 76 years. Overall, 335 patients (25.5%) died with 211 of these (16%) suffering from CVD. Patients in Q4 showed a higher cumulative probability of CVD compared to patients in Q1–Q3. On multivariable analysis, patients in Q4 were at higher risk of CVD [hazard ratio (HR) = 1.47, 95% confidence interval (CI) 1.09–1.98, p = 0.011]. WBCc as a continuous variable was also independently associated with the study end point (HR = 1.043; 95% CI 1.02–1.07; p = 0.001). However, the incorporation of WBCc into the GRACE score did not improve either prediction of risk (C-index = 0.796 for GRACE score with or without WBCc) or classification of risk [relative integrated discrimination improvement = 0.0154, 95% CI) –0.029 to 0.0618; continuous net reclassification improvement = –0.0676, 95% CI –0.2149–0.0738). Conclusions: WBCc was an independent predictor of 3-year CVD in patients with NSTE-ACS. However, it did not add prognostic information beyond the GRACE score.

Published
2013

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