1. Catheter Closure Through a Venous Approach of Patent Ductus Arteriosus in Small Pediatric Patients Using Combined Angiographic and Echocardiographic Guidance.
- Author
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Thanopoulos BV, Ninios V, Dardas P, Giannopoulos A, Deleanou D, and Iancovici S
- Subjects
- Cardiac Catheters, Child, Preschool, Ductus Arteriosus, Patent diagnosis, Equipment Design, Female, Humans, Infant, Male, Treatment Outcome, Angiography methods, Cardiac Catheterization instrumentation, Cardiac Surgical Procedures methods, Catheterization, Central Venous methods, Ductus Arteriosus, Patent surgery, Echocardiography, Doppler, Color methods, Surgery, Computer-Assisted methods
- Abstract
The standard technique of catheter closure of patent ductus arteriosus (PDA) may be associated with arterial complications particularly in small pediatric patients. The aim of this study was to evaluate whether catheter closure of PDA in small children using an exclusive venous approach is a safe and effective alternative to closure with the standard technique. One hundred-twelve patients, aged 2 to 24 months, were randomly assigned in a 1:1 ratio to catheter closure of PDA using the standard technique (group 1) and an exclusive venous approach (group 2), respectively. In group 2, the procedure was guided using hand injections of contrast media through the delivery sheath and 2-dimensional and color Doppler echocardiography. Group 1: the PDA diameter ranged from 2 to 5.5 mm and the device diameter ranged from 4 to 8 mm. The PDA occluders were permanently implanted in all patients. Five losses of the arterial pulses that were restored with intravenous infusion of heparin and recombinant tissue plasminogen activator (rtPA), and 4 groin hematomas were the main complications of the procedure. Group 2: the mean PDA diameter ranged from 2.5 to 6 mm and the device diameter ranged from 3 to 8 mm. The PDA occluders were permanently implanted in all but 2 patients. There were no complications. Complete echocardiographic closure of PDA at 1-month follow-up was observed in all 110 patients. Exclusive transvenous PDA occlusion is an effective and safe technique that prevents the arterial complications of the standard approach in small children., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2016
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