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Start Over Author "John P Salvas" Topic cardiac dysfunction
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1. Improving characterization of hypertrophy-induced murine cardiac dysfunction using four-dimensional ultrasound-derived strain mapping

Author

Andrea S. Pereyra, Craig J. Goergen, Frederick W. Damen, Jessica M. Ellis, and John P Salvas

Subjects
Mice, Knockout, Carnitine O-Palmitoyltransferase, Physiology, business.industry, Ultrasound, Cardiomegaly, Heart, Strain mapping, Ventricular Function, Left, Cardiac dysfunction, Muscle hypertrophy, Contractility, Mice, Physiology (medical), Global function, Animals, Medicine, Female, Cardiology and Cardiovascular Medicine, business, Four dimensional ultrasound, Echocardiography, Four-Dimensional, Biomedical engineering
Abstract

Mouse models of cardiac disease have become essential tools in the study of pathological mechanisms, but the small size of rodents makes it challenging to quantify heart function with noninvasive imaging. Building off recent developments in high-frequency four-dimensional ultrasound (4DUS) imaging, we have applied this technology to study cardiac dysfunction progression in a murine model of metabolic cardiomyopathy. Cardiac knockout of carnitine palmitoyltransferase 2 (

Published
2021
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