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7 results on '"Sorropago G"'

1. SAT-TAVI (single antiplatelet therapy for TAVI) study: a pilot randomized study comparing double to single antiplatelet therapy for transcatheter aortic valve implantation.

Author

Stabile E, Pucciarelli A, Cota L, Sorropago G, Tesorio T, Salemme L, Popusoi G, Ambrosini V, Cioppa A, Agrusta M, Catapano D, Moscariello C, Trimarco B, Esposito G, and Rubino P

Subjects
Aged, Aged, 80 and over, Aortic Valve Stenosis mortality, Cardiac Catheterization mortality, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Pilot Projects, Transcatheter Aortic Valve Replacement mortality, Treatment Outcome, Aortic Valve Stenosis drug therapy, Aortic Valve Stenosis surgery, Cardiac Catheterization methods, Platelet Aggregation Inhibitors administration & dosage, Transcatheter Aortic Valve Replacement methods
Abstract

Background: Common clinical practice recommends dual antiplatelet therapy (DAPT) for transcatheter aortic valve implantation (TAVI). The aim of the study was to evaluate, in a double blind randomized study, the safety of TAVI, with adjunctive pharmacotherapy consisting of single antiplatelet therapy., Methods and Results: From April 2010 to April 2011, 120 consecutive patients, undergoing TAVI, have been enrolled in the study. Patients were randomly assigned to DAPT group (aspirin and clopidogrel 75 mg/qd or ticlopidine 500 mg/bid) or ASA group (aspirin only). TAVI device was the Sapien XT-Novaflex Delivery System (Edwards Lifesciences, Inc.). All patients were followed up to 6 months. Device success was achieved in 100% of patients. No difference in the VARC combined 30 day safety endpoint, all cause and cardiovascular mortality was observed. At 30 days vascular complications were reduced in the ASA group (p<0.05). No differences in the clinical status were detected between the groups up to 6 months., Conclusions: This study suggests that TAVI procedures can be performed without DAPT without increasing the morbidity and mortality. These findings, if confirmed in a larger multicenter randomized trial, will no longer support the use of DAPT for TAVI., (Copyright © 2014. Published by Elsevier Ireland Ltd.)

Published
2014
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2. Bioprostheses "thrombosis" after transcatheter aortic valve replacement.

Author

Cota L, Stabile E, Agrusta M, Sorropago G, Pucciarelli A, Ambrosini V, Mottola G, Esposito G, and Rubino P

Subjects
Aged, Aged, 80 and over, Aortic Valve surgery, Bicuspid Aortic Valve Disease, Female, Heart Defects, Congenital diagnostic imaging, Heart Valve Diseases diagnostic imaging, Heart Valve Prosthesis adverse effects, Humans, Male, Thrombosis etiology, Ultrasonography, Aortic Valve diagnostic imaging, Bioprosthesis adverse effects, Cardiac Catheterization adverse effects, Heart Defects, Congenital etiology, Heart Valve Diseases etiology, Heart Valve Prosthesis Implantation adverse effects, Thrombosis diagnostic imaging
Published
2013
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3. [Transcatheter aortic valve implantation in patients with severe symptomatic aortic stenosis: position statement of the Italian Society of Interventional Cardiology (SICI-GISE) on minimum standards for hospitals and operators].

Author

Santoro G, Bedogni F, Ambrosini V, Berti S, Petronio AS, Ramondo A, Salvi A, Sorropago G, Ussia GP, and Cremonesi A

Subjects
Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis therapy, Equipment and Supplies standards, Hospital Design and Construction standards, Humans, Italy, Risk Assessment, Severity of Illness Index, Societies, Medical, Ultrasonography, Aortic Valve Stenosis surgery, Cardiac Catheterization methods, Cardiac Catheterization standards, Cardiology standards, Heart Valve Prosthesis Implantation methods, Heart Valve Prosthesis Implantation standards
Abstract

At present, transcatheter aortic valve implantation (TAVI) is a proven treatment option for patients with symptomatic degenerative aortic stenosis at high risk for conventional surgery. In countries where TAVI is currently performed, the number of procedures and centers involved has been continuously increasing. The present document from the Italian Society of Interventional Cardiology (SICI-GISE) aims to improve the available evidence and current consensus on this topic through the definition of training needs and knowledge base for both operators and centers.

Published
2012
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4. Acute left main obstructions following TAVI.

Author

Stabile E, Sorropago G, Cioppa A, Cota L, Agrusta M, Lucchetti V, and Rubino P

Subjects
Aged, Aged, 80 and over, Angioplasty, Balloon, Coronary instrumentation, Aortic Valve Stenosis diagnostic imaging, Aortography, Catheterization adverse effects, Coronary Angiography, Coronary Stenosis diagnostic imaging, Coronary Stenosis therapy, Female, Heart Valve Prosthesis Implantation methods, Humans, Male, Risk Assessment, Risk Factors, Severity of Illness Index, Stents, Treatment Outcome, Aortic Valve Stenosis therapy, Cardiac Catheterization adverse effects, Coronary Stenosis etiology, Heart Valve Prosthesis Implantation adverse effects
Abstract

Aims: Transcatheter aortic valve implantation (TAVI) is becoming a safe and effective technique for treating symptomatic aortic valvular stenosis (AVS) as an alternative to surgery in very high-risk patients. A possible consequence of valve implantation is the obstruction of coronary ostia., Methods and Results: Here we report five cases of angiographically confirmed left main (LM) obstruction, occurred immediately after balloon expandable aortic valve implantations at our institution. In four of these cases, LM obstruction was resolved with an emergency percutaneous coronary intervention (PCI). In the remaining case, obstruction transiently occurred only at the time of balloon valvuloplasty and did not required treatment. During this type of intervention, performing an aortography at the time of balloon valvuloplasty could help to identify patients at risk for coronary obstructions., Conclusions: These cases illustrate that obstruction of the coronary ostia following TAVI is a possible complication. As the use of TAVI becomes widespread, the operators should be aware of this dangerous complication in their case preparation should it arise.

Published
2010

5. Radiation dose exposure during cardiac and peripheral arteries catheterisation.

Author

Kocinaj D, Cioppa A, Ambrosini G, Tesorio T, Salemme L, Sorropago G, Rubino P, and Picano E

Subjects
Adult, Aortography methods, Coronary Angiography methods, Dose-Response Relationship, Radiation, Humans, Incidence, Neoplasms, Radiation-Induced epidemiology, Radionuclide Ventriculography methods, Retrospective Studies, Risk Factors, Aortography adverse effects, Cardiac Catheterization, Catheterization, Peripheral, Coronary Angiography adverse effects, Neoplasms, Radiation-Induced etiology, Radionuclide Ventriculography adverse effects
Abstract

Background: Ionising radiation carries an oncogenic risk which is linearly related to the dose. An estimation of the effective dose can be obtained from the measurements of the dose-area product (DAP), which is a measure of stochastic risk and a potential quality indicator., Aim: To assess radiation exposure of patients in a large volume cardiac cath-lab., Methods: A retrospective analysis of adult cardiac and peripheral percutaneous procedures (April to December 2004) was carried out to determine the DAP and estimated risk of malignancy. We identified 6 groups: Group 1 (n=100, coronary angiography and ventriculography); Group 2 (n=50, carotid stenting); Group 3 (n=50, aortography+coronary angiography+ventriculography); Group 4 (n=100, inferior extremities angiography+predilatation and stenting); Group 5 (n=100, coronary angiography+ventriculography+direct coronary stenting); Group 6 (n=100, coronary angiography+ventriculography+coronary predilation and stenting). Dose-area product meter attached on the X-ray unit was used for the estimation of the radiation dose received by the patient during the procedures., Results: DAP values (mean+/-S.D.) ranged from 41+/-30 Gy cm2 in Group 1 (lowest) to 118+/-89 Gy cm2 in Group 6 (highest). Within each group, individual radiation exposure varies substantially: from 11 to 200 Gy cm2 in Group 1, and from 30 to 733 Gy cm2 in Group 6 patients. Average exposure in a Group 6 patient corresponds to a risk of mortality from a malignancy of about 1 in 1000., Conclusion: The radiation dose varies substantially across different types of procedures and up to tenfold within the same procedure. The enhanced knowledge of radiation dose might help the cardiologist to implement radiation sparing procedures eventually minimizing patient and operator radiation hazards in invasive cardiology.

Published
2006
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6. Noninvasive Estimation of Aortic Stiffness Through Different Approaches

Author

Andrea Grillo, Lucia Salvi, Andrea Faini, Renzo Carretta, Matteo Rovina, Corrado Baldi, Sandrine Millasseau, Giovanni Sorropago, A. Sorropago, Filippo Scalise, Giulia Furlanis, Paolo Salvi, Francesco Moretti, Alberto Avolio, Lan Gao, Gianfranco Parati, Salvi, P, Scalise, F, Rovina, M, Moretti, F, Salvi, L, Grillo, A, Gao, L, Baldi, C, Faini, A, Furlanis, G, Sorropago, A, Millasseau, S, Sorropago, G, Carretta, R, Avolio, A, and Parati, G

Subjects
Male, Coronary angiography, Pulse Wave Analysis, Coronary Stenosi, pulse wave velocity, medicine.medical_treatment, arteriosclerosi, Pulsatile flow, Hemodynamics, Pulse Wave Analysi, 030204 cardiovascular system & hematology, Coronary Angiography, Sensitivity and Specificity, Severity of Illness Index, 03 medical and health sciences, Vascular Stiffness, 0302 clinical medicine, Nuclear magnetic resonance, hemodynamic, Cardiovascular Disease, Internal Medicine, medicine, 030212 general & internal medicine, Pulse wave velocity, Aged, Cardiac catheterization, Physics, cardiac catheterization, Blood Pressure Determination, Middle Aged, Prospective Studie, Blood pressure, vascular stiffne, Italy, Pulsatile Flow, Linear Model, Aortic stiffness, Cohort Studie, coronary artery disease, Blood Flow Velocity, Human
Abstract

Aortic pulse wave velocity is a worldwide accepted index to evaluate aortic stiffness and can be assessed noninvasively by several methods. This study sought to determine if commonly used noninvasive devices can all accurately estimate aortic pulse wave velocity. Pulse wave velocity was estimated in 102 patients (aged 65±13 years) undergoing diagnostic coronary angiography with 7 noninvasive devices and compared with invasive aortic pulse wave velocity. Devices evaluating carotid-femoral pulse wave velocity (Complior Analyse, PulsePen ET, PulsePen ETT, and SphygmoCor) showed a strong agreement between each other ( r >0.83) and with invasive aortic pulse wave velocity. The mean difference ±SD with the invasive pulse wave velocity was −0.73±2.83 m/s ( r =0.64) for Complior-Analyse: 0.20±2.54 m/s ( r =0.71) for PulsePen-ETT: −0.04±2.33 m/s ( r =0.78) for PulsePen ET; and −0.61±2.57 m/s ( r =0.70) for SphygmoCor. The finger-toe pulse wave velocity, evaluated by pOpmètre, showed only a weak relationship with invasive aortic recording (mean difference ±SD =−0.44±4.44 m/s; r =0.41), and with noninvasive carotid-femoral pulse wave velocity measurements ( r r =0.23; 1.04±2.27 m/s, r =0.77; and −1.01±2.54 m/s, r =0.71, respectively), revealing a negative proportional bias at Bland-Altman plot. Aortic pulse wave velocity values provided by BPLab and Mobil-O-Graph were entirely dependent on age-squared and peripheral systolic blood pressure (cumulative r 2 =0.98 and 0.99, respectively). Thus, among the methods evaluated, only those assessing carotid-femoral pulse wave velocity (Complior Analyse, PulsePen ETT, PulsePen ET, and SphygmoCor) appear to be reliable approaches for estimation of aortic stiffness.

Published
2019

7. Acute left main obstructions following TAVI

Author

Marco Agrusta, Vincenzo Lucchetti, Linda Cota, Angelo Cioppa, Paolo Rubino, Giovanni Sorropago, Eugenio Stabile, Stabile, Eugenio, Sorropago, G, Cioppa, A, Cota, L, Agrusta, M, Lucchetti, V, and Rubino, P.

Subjects
Male, Aortic valve, Cardiac Catheterization, medicine.medical_specialty, Aortography, medicine.medical_treatment, Coronary Angiography, Risk Assessment, Severity of Illness Index, Catheterization, Risk Factors, Internal medicine, Severity of illness, medicine, Humans, Angioplasty, Balloon, Coronary, Aged, Cardiac catheterization, Aged, 80 and over, Heart Valve Prosthesis Implantation, medicine.diagnostic_test, business.industry, Coronary Stenosis, Aortic Valve Stenosis, medicine.disease, Surgery, Treatment Outcome, medicine.anatomical_structure, Aortic valve stenosis, Conventional PCI, cardiovascular system, Cardiology, Female, Stents, Cardiology and Cardiovascular Medicine, business, Complication, Emergency percutaneous coronary intervention
Abstract

AIMS Transcatheter aortic valve implantation (TAVI) is becoming a safe and effective technique for treating symptomatic aortic valvular stenosis (AVS) as an alternative to surgery in very high-risk patients. A possible consequence of valve implantation is the obstruction of coronary ostia. METHODS AND RESULTS Here we report five cases of angiographically confirmed left main (LM) obstruction, occurred immediately after balloon expandable aortic valve implantations at our institution. In four of these cases, LM obstruction was resolved with an emergency percutaneous coronary intervention (PCI). In the remaining case, obstruction transiently occurred only at the time of balloon valvuloplasty and did not required treatment. During this type of intervention, performing an aortography at the time of balloon valvuloplasty could help to identify patients at risk for coronary obstructions. CONCLUSIONS These cases illustrate that obstruction of the coronary ostia following TAVI is a possible complication. As the use of TAVI becomes widespread, the operators should be aware of this dangerous complication in their case preparation should it arise.

Published
2010

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