1. Bladder carcinosarcoma treated by cystectomy and adjuvant chemotherapy with good outcomes: a case report.
- Author
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Kouhen F, Dahbi Z, Afif M, Chihabeddine M, Errafiy N, Oqbani K, Omor Y, and Elhossini A
- Subjects
- Male, Humans, Aged, Cystectomy, Urinary Bladder diagnostic imaging, Urinary Bladder surgery, Urinary Bladder pathology, Chemotherapy, Adjuvant, Urinary Bladder Neoplasms drug therapy, Urinary Bladder Neoplasms surgery, Carcinoma, Transitional Cell pathology, Pelvic Neoplasms surgery, Carcinosarcoma drug therapy, Carcinosarcoma pathology, Soft Tissue Neoplasms surgery
- Abstract
Background: Primary carcinosarcoma of the bladder is a rare and highly aggressive tumor, representing less than 1% of all bladder neoplasms. There is no specific treatment guideline has for carcinosarcoma of the bladder, and majority of published patients was treated exclusively by surgery., Case Presentation: We report a case of 65-year-old Moroccan man, presented with macroscopic hematuria, pollakiuria and painful urination. Histological analysis showed a biphasic epithelial and mesenchymal proliferation, with invasion of lamina propria and muscularis, compatible with diagnosis of bladder carcinosarcoma. The patient was treated with cystectomy and adjuvant chemotherapy based on gemcitabin-cisplatin, 18 months after treatment, patient still free of recurrence., Conclusion: Carcinosarcoma of the urinary bladder is a rare and aggressive tumor regardless treatment. A multidisciplinary management based on radical cystectomy and combined adjuvant treatments can improve prognosis. In this work, we suggest to propose adjuvant chemotherapy whenever possible., (© 2023. The Author(s).)
- Published
- 2023
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