1. Clinicopathological features and prognostic factors of solid pseudopapillary neoplasms of pancreas.
- Author
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Wu JH, Tian XY, Liu BN, Li CP, Zhao M, and Hao CY
- Subjects
- Adolescent, Adult, Aged, Carcinoma, Papillary diagnostic imaging, Carcinoma, Papillary epidemiology, Carcinoma, Papillary surgery, Child, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neoplasm Metastasis, Pancreas diagnostic imaging, Pancreas surgery, Pancreatectomy, Pancreatic Neoplasms diagnostic imaging, Pancreatic Neoplasms epidemiology, Pancreatic Neoplasms surgery, Prognosis, Progression-Free Survival, Retrospective Studies, Tomography, X-Ray Computed, Young Adult, Carcinoma, Papillary pathology, Pancreas pathology, Pancreatic Neoplasms pathology
- Abstract
.To explore the clinicopathological features of solid pseudopapillary neoplasm (SPN) of pancreas and to analyze the related factors of SPNs with aggressive behavior. Clinical data of SPN patients admitted in the Single Center of Peking University Cancer Hospital from January 2007 to September 2017 were retrospectively analyzed. The correlations of clinicopathological features with aggressive SPNs and distant metastasis after curative resection were analyzed using univariate analysis. Twelve of the total 54 SPN patients were diagnosed as aggressive SPNs. Univariate analysis suggested clinical features had no correlations with aggressive SPNs. Patients were followed up for an average of 5.0 years, four of them developed distant metastases. Univariate analysis indicated that distant metastasis of SPNs was correlated with the aggressive behaviors (P=0.031). Moreover, vessels invasion (VI) and Ki-67>4% (P=0.012) were the independent risk factors of distant metastasis of SPNs. The aggressive SPNs, especially VI and Ki-67>4% are the independent factors correlated with distant metastases after SPNs surgery. more...
- Published
- 2019