1. Developing intrathoracic sentinel lymph node mapping with near-infrared fluorescent imaging in non-small cell lung cancer.
- Author
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Gilmore DM, Khullar OV, and Colson YL
- Subjects
- Carcinoma, Non-Small-Cell Lung therapy, History, 19th Century, History, 20th Century, History, 21st Century, Humans, Lung Neoplasms therapy, Lymphatic Metastasis, Neoplasm Staging, Predictive Value of Tests, Prognosis, Sentinel Lymph Node Biopsy, Video Recording, Carcinoma, Non-Small-Cell Lung secondary, Luminescent Measurements history, Luminescent Measurements instrumentation, Lung Neoplasms pathology, Lymph Nodes pathology, Molecular Diagnostic Techniques history, Molecular Diagnostic Techniques instrumentation, Spectroscopy, Near-Infrared history, Spectroscopy, Near-Infrared instrumentation
- Abstract
With poor survival and high recurrence rates, early-stage lung cancer currently appears to be understaged or undertreated, or both. Although sentinel lymph node biopsy is standard for patients with breast cancer and melanoma, its success has been unreliable in non-small cell lung cancer. Sentinel lymph node biopsy might aid in the identification of lymph nodes at the greatest risk of metastasis and allow for more detailed analysis to select for patients who might benefit from adjuvant therapy. The early results in our recent clinical trial of patients with early-stage lung cancer have suggested that near-infrared imaging might offer a platform for reliable sentinel lymph node identification in these patients., (Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.)
- Published
- 2012
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