1. Comparison of percutaneous microwave/radiofrequency ablation liver partition and portal vein embolization versus transarterial chemoembolization and portal vein embolization for planned hepatectomy with insufficient future liver remnant.
- Author
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Ye TW, Fu TW, Du CF, Yue RC, Jiang QT, Zhong ZH, Zhao Q, Zhang CW, Liu J, Liu JW, Luo ZY, Fan XM, Hong DF, Cheng J, and Xiao ZQ
- Subjects
- Humans, Male, Female, Middle Aged, Retrospective Studies, Aged, Adult, Liver surgery, Liver blood supply, Embolization, Therapeutic methods, Treatment Outcome, Postoperative Complications etiology, Postoperative Complications epidemiology, Survival Rate, China epidemiology, Combined Modality Therapy, Hepatectomy methods, Liver Neoplasms therapy, Liver Neoplasms surgery, Portal Vein, Chemoembolization, Therapeutic methods, Radiofrequency Ablation methods, Microwaves therapeutic use, Carcinoma, Hepatocellular therapy, Carcinoma, Hepatocellular surgery
- Abstract
Background: In China, both percutaneous microwave/radiofrequency ablation liver partition plus portal vein embolization (PALPP) and transarterial chemoembolization (TACE) plus portal vein embolization (PVE) have been utilized in planned hepatectomy. However, there is a lack of comparative studies on the effectiveness of these two techniques for cases with insufficient future liver remnant (FLR)., Methods: Patients were categorized into either the PALPP group or the TACE + PVE group. Clinical data, including FLR growth rate, complications, secondary resection rate, and overall survival rate, were compared and analyzed for both groups retrospectively., Results: Between December 2014 and October 2021, a total of 29 patients underwent TACE + PVE (n = 12) and PALPP (n = 17). In the TACE + PVE group, 7 patients successfully underwent two-stage hepatectomy, while in the PALPP group, 13 patients underwent the procedure (two-stage resection rate: 58.3% vs. 76.5%, P = 0.42). There were no significant differences in postoperative complications of one-stage procedures (11.8% vs. 8.3%, P > 0.05) and second-stage resection complication (0% vs. 46.2%, P = 0.05) between the TACE + PVE and PALPP groups. However, the PALPP group demonstrated a shorter time to FLR volume growth for second-stage resection (18.5 days vs. 66 days, P = 0.001) and KGR (58.5 ml/week vs. 7.7 ml/week, P = 0.001)., Conclusions: Compared with TACE + PVE, PALPP results in a more significant increase in FLR volume and a higher rate of two-stage resection without increasing postoperative complications., (© 2024. The Author(s).)
- Published
- 2024
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