Search

Your search keyword '"DI GESARO V"' showing total 3 results
Start Over Author "DI GESARO V" Topic carcinoma, hepatocellular
3 results on '"DI GESARO V"'

1. Hepatocellular carcinoma: comparison of two different periods at the same center.

Author

Soresi M, La Spada E, Giannitrapani L, Campagna E, Di Gesaro V, Granà W, Sandonato L, Brancatelli G, Rotolo G, Affronti A, Messina S, and Montalto G

Subjects
Adult, Aged, Aged, 80 and over, Alcohol Drinking adverse effects, Carcinoma, Hepatocellular diagnosis, Carcinoma, Hepatocellular pathology, Female, Hepatitis B complications, Hepatitis C complications, Humans, Italy, Liver Function Tests, Liver Neoplasms diagnosis, Liver Neoplasms pathology, Male, Middle Aged, Neoplasm Staging, Time Factors, alpha-Fetoproteins analysis, Carcinoma, Hepatocellular etiology, Liver Neoplasms etiology
Abstract

Aims: To analyze the main etiological factors and some clinical characteristics of patients with HCC at diagnosis and to compare them with those we described ten years ago., Methods: 179 patients were included in Group 1, while 132 patients were included in Group 2. For all patients age, sex, serum markers of hepatitis B and C viruses, alcohol consumption, serum alpha feto-protein (AFP) levels and the main liver function parameters at HCC diagnosis were recorded., Results: Mean age was 66.0 years for Group 1 and 69.0 for Group 2 (P=0.005). HCV was responsible for 80.3% of HCC cases in Group 2 versus 72% in Group 1 (P=0.005). HBV alone and co-infection of HCV+HBV decreased, but not significantly. In Group 1 only four patients had an underlying normal liver, while in Group 2 no patients showed an underlying normal liver (P=ns). HCC was more frequently associated with Child class A in Group 2 (P=0.0001), whereas in Group 1 it was more frequently associated with class C (P=0.0001). Staging of HCC correlated inversely when patients of Groups 1 and 2 were compared (P<0.03). AFP serum levels were above normal in 72% of cases in Group 1 and in 41.5% in Group 2 (P=0.0001)., Conclusion: This study shows that over the last decade a number of characteristics of patients with HCC in our region have changed, particularly age at onset of HCC, staging of underlying liver disease and staging of HCC., (Copyright 2009 Elsevier B.V. All rights reserved.)

Published
2010
Full Text
View/download PDF

2. [Acute renal failure as a complication of transarterial chemoembolization in a patient with hepatocellular carcinoma].

Author

La Spada E, La Spada M, Brusca T, Campagna ME, Di Gesaro V, Terranova A, Sandonato L, and Soresi M

Subjects
Acute Kidney Injury therapy, Aged, Antineoplastic Agents administration & dosage, Humans, Infusions, Intra-Arterial, Male, Risk Factors, Treatment Outcome, Acute Kidney Injury chemically induced, Carcinoma, Hepatocellular therapy, Chemoembolization, Therapeutic adverse effects, Liver Neoplasms therapy
Abstract

Transarterial chemoembolization (TACE) is included among the wide therapeutic tools for the treatment of hepatocellular carcinoma (HCC), tumour with high frequency and malignancy. The approach is invasive and, beyond the discomfort for the patient, it is charged by a number of side effects and complications. In this study we report the case of renal acute failure of hypovolemic origin, as a consequence of a TACE in a patient suffering from HCC, occurred after one week of intervention. The different possible mechanisms involved in the pathogenesis of this complication are discussed.

Published
2007

3. Hepatocellular carcinoma: comparison of two different periods at the same center

Author

Salvatore Messina, Giuseppe Montalto, Emanuele La Spada, Valeria Di Gesaro, Lydia Giannitrapani, Luigi Sandonato, Walter Granà, Maurizio Soresi, Giuseppe Brancatelli, Elisa Campagna, Andrea Affronti, Giuseppe Rotolo, Soresi M, La Spada E, Giannitrapani L, Campagna E, Di Gesaro V, Granà W, Sandonato L, Brancatelli G, Rotolo G, Affronti A, Messina S, and Montalto G

Subjects
Oncology, Adult, Male, medicine.medical_specialty, Settore MED/09 - Medicina Interna, Carcinoma, Hepatocellular, Time Factors, Alcohol Drinking, Alpha (ethology), Gastroenterology, hepatocellular carcinoma, Etiology, Staging, Diagnosis, Liver disease, Liver Function Tests, Internal medicine, Internal Medicine, medicine, Humans, Aged, Neoplasm Staging, Aged, 80 and over, medicine.diagnostic_test, business.industry, Liver Neoplasms, Hepatitis C, Hepatitis B, Middle Aged, medicine.disease, digestive system diseases, Italy, Hepatocellular carcinoma, Etiology, Female, Liver function, alpha-Fetoproteins, Liver function tests, business
Abstract

Aims: To analyze the main etiological factors and some clinical characteristics of patients with HCC at diagnosis and to compare them with those we described ten years ago. Methods: 179 patients were included in Group 1, while 132 patients were included in Group 2. For all patients age, sex, serum markers of hepatitis B and C viruses, alcohol consumption, serum alpha feto-protein (AFP) levels and the main liver function parameters at HCC diagnosis were recorded. Results: Mean age was 66.0 years for Group 1 and 69.0 for Group 2 (P=0.005). HCV was responsible for 80.3% of HCC cases in Group 2 versus 72% in Group 1 (P=0.005). HBV alone and co-infection of HCV+HBV decreased, but not significantly. In Group 1 only four patients had an underlying normal liver, while in Group 2 no patients showed an underlying normal liver (P=ns). HCC was more frequently associated with Child class A in Group 2 (P=0.0001), whereas in Group 1 it was more frequently associated with class C (P=0.0001). Staging of HCC correlated inversely when patients of Groups 1 and 2 were compared (Pb0.03). AFP serum levels were above normal in 72% of cases in Group 1 and in 41.5% in Group 2 (P=0.0001). Conclusion: This study shows that over the last decade a number of characteristics of patients with HCC in our region have changed, particularly age at onset of HCC, staging of underlying liver disease and staging of HCC.

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results