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The monitoring and the control of air pollution which is a consequence of the activities of district heating plants in the area of Niš have indicated that there is a cause and effect relationship between the emitted pollutants and air quality on one hand, and health risk on the other hand. The aim of this paper is to determine the correlation between district heating plants, air quality and health risk. The evidence of this connection is the hazardous health quotient and the level of total carcinogenic risk in comparison to measured immission concentration and expected immission concentrations of pollutants from district heating plants in the city. [ABSTRACT FROM AUTHOR]