1. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) (vol 11, 33, 2016)
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Sartelli, M., Weber, D. G., Ruppe, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, Anna Maria, Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Jusoh, A. Che, Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzman-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., McFarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Junior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., Van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., Viale, P., Universita 'La Sapienza' Roma (Istituto CNR), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Universidade de Aveiro, Laboratoire matériaux et microélectronique de Provence (L2MP), Université Paul Cézanne - Aix-Marseille 3-Université de Provence - Aix-Marseille 1-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Côte d'Ivoire, Réseau International des Instituts Pasteur (RIIP), National Defence University of Malaysia [Kuala Lumpur], Max Planck Institute for the Physics of Complex Systems (MPI-PKS), Max-Planck-Gesellschaft, Center for Plant Molecular Biology, Plant Physiology, and Biophysical Chemistry, University of Tübingen, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Dipartimento di Fisica 'Giuseppe Occhialini' = Department of Physics 'Giuseppe Occhialini' [Milano-Bicocca], Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Atmospheric and Environmental Research, Inc. (AER), Zhejiang University, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), and COMBE, Isabelle
- Subjects
[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,Carbapenems ,Antimicrobial Resistance ,Invasive Candidiasis ,Methicillin Resistant Staphylococcus Aureus ,Tigecycline ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
International audience; Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance.The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria.An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
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- 2017
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