Search

Your search keyword '"De Rose, D.U."' showing total 2 results
Start Over Author "De Rose, D.U." Topic candida
2 results on '"De Rose, D.U."'

1. Incidence and risk factors of bacterial sepsis and invasive fungal infection in neonates and infants requiring major surgery: an Italian multicentre prospective study.

Author

Auriti, C., De Rose, D.U., Santisi, A., Martini, L., Ronchetti, M.P., Ravà, L., Antenucci, V., Bernaschi, P., Serafini, L., Catarzi, S., Fiorini, P., Betta, P., Scuderi, M.G., Di Benedetto, V., Ferrari, S., Maino, M., Cavigioli, F., Cocchi, I., Giuffré, M., and Bonanno, E.

Abstract

Background: Limited data are currently available on the incidence rates and risk factors for bacterial sepsis and invasive fungal infections (IFIs) among neonates and infants undergoing major surgery.Aim: To assess the incidence of bacterial sepsis and IFI, fungal colonization, risk factors for sepsis, and mortality in neonates and infants aged <3 months undergoing major surgery.Methods: A multicentre prospective study was conducted involving 13 level-3 neonatal intensive care units in Italy, enrolling all infants aged ≤3 months undergoing major surgery.Findings: From 2018 to 2021, 541 patients were enrolled. During hospitalization, 248 patients had a bacterial infection, and 23 patients had a fungal infection. Eighty-four patients were colonized by fungal strains. Overall, in-hospital mortality was 2.8%, but this was higher in infected than in uninfected infants (P = 0.034). In multivariate analysis, antibiotic exposure before surgery, ultrasound-guided or surgical placement of vascular catheters, vascular catheterization duration, and gestational age ≤28 weeks were all associated with bacterial sepsis. The risk of IFI was markedly higher in colonized infants (odds ratio (OR): 8.20; P < 0.001) and was linearly associated with the duration of vascular catheterization. Fungal colonization in infants with abdominal surgery increased the probability of IFI 11-fold (OR: 11.1; P < 0.001).Conclusion: Preventive strategies such as early removal of vascular catheters and the fluconazole prophylaxis should be considered to prevent bacterial and fungal sepsis in infants undergoing abdominal surgery, and even more so in those with fungal colonization. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

2. incidence and risk factors of bacterial sepsis and invasive fungal infection in neonates and infants requiring major surgery: an Italian multicentre prospective study

Author

C, Auriti, D U, De Rose, A, Santisi, L, Martini, M P, Ronchetti, L, Ravà, V, Antenucci, P, Bernaschi, L, Serafini, S, Catarzi, P, Fiorini, P, Betta, M G, Scuderi, V, Di Benedetto, S, Ferrari, M, Maino, F, Cavigioli, I, Cocchi, M, Giuffré, E, Bonanno, C, Tzialla, J, Bua, L, Pugni, B, Della Torre, G, Nardella, D, Mazzeo, P, Manzoni, I, Capolupo, M, Ciofi Degli Atti, A, Dotta, M, Stronati, M, Raponi, F, Mosca, P, Bagolan, Auriti C., De Rose D.U., Santisi A., Martini L., Ronchetti M.P., Rava L., Antenucci V., Bernaschi P., Serafini L., Catarzi S., Fiorini P., Betta P., Scuderi M.G., Di Benedetto V., Ferrari S., Maino M., Cavigioli F., Cocchi I., Giuffre M., Bonanno E., Tzialla C., Bua J., Pugni L., Della Torre B., Nardella G., Mazzeo D., Manzoni P., Capolupo I., Ciofi degli Atti M., Dotta A., Stronati M., Raponi M., Mosca F., and Bagolan P.

Subjects
Microbiology (medical), Settore MED/38 - Pediatria Generale e Specialistica, Fungal infection, Antifungal Agents, Incidence, Infant, Newborn, Infant, General Medicine, Candida, Fungal colonization, Neonatal sepsis, Surgery, Infectious Diseases, Mycoses, Risk Factors, Sepsis, Humans, Prospective Studies, Neonatal sepsi, fungal infection Fungal colonization Neonatal sepsis Surgery Candida, Invasive Fungal Infections
Abstract

Background: Limited data are currently available on the incidence rates and risk factors for bacterial sepsis and invasive fungal infections (IFIs) among neonates and infants undergoing major surgery. Aim: To assess the incidence of bacterial sepsis and IFI, fungal colonization, risk factors for sepsis, and mortality in neonates and infants aged

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results