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Your search keyword '"Ion-substituted hydroxyapatite"' showing total 2 results
Start Over Descriptor "Ion-substituted hydroxyapatite" Topic calcium phosphates
2 results on '"Ion-substituted hydroxyapatite"'

1. Fabrication and characterization of biomimetic hydroxyapatite thin films for bone implants by direct ablation of a biogenic source.

Author

Graziani, Gabriela, Berni, Matteo, Gambardella, Alessandro, De Carolis, Monica, Maltarello, Maria Cristina, Boi, Marco, Carnevale, Gianluca, and Bianchi, Michele

Subjects
*BIOMIMETIC materials, *HYDROXYAPATITE coating, *THIN films
Abstract

Abstract Biomimetic bone apatite coatings were realized for the first time by the novel Ionized Jet Deposition technique. Bone coatings were deposited on titanium alloy substrates by pulsed electron ablation of deproteinized bovine bone shafts in order to resemble bone apatite as closely as possible. The composition, morphology and mechanical properties of the coatings were characterized by GI-XRD, FT-IR, SEM-EDS, AFM, contact angle measurements, micro-scratch and screw-insertion tests. Different post-treatment annealing conditions (from 350 °C to 425 °C) were investigated. Bone apatite coatings exhibited a nanostructured surface morphology and a composition closely resembling that of the deposition target (i.e. natural bone apatite), also regarding the presence of magnesium and sodium ions. Crystallinity and composition of the coatings were strongly influenced by annealing temperature and duration; in particular, upon annealing at 400 °C and above, a crystallinity similar to that of bone was achieved. Finally, adhesion to the titanium substrate and hydrophilicity were significantly enhanced upon annealing, all characteristics being known to have a strong positive impact on promoting host cells attachment, proliferation and differentiation. Highlights • Biomimetic thin films were obtained by pulsed electron deposition. • Films obtained exhibit composition perfectly resembling the deposition targets. • Film crystallinity is tuned by post heating treatment up to resembling that of bone. • Upon annealing, high adhesion and good hydrophilicity can also be obtained. [ABSTRACT FROM AUTHOR]

Published
2019
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2. Fabrication and characterization of biomimetic hydroxyapatite thin films for bone implants by direct ablation of a biogenic source

Author

M C Maltarello, Marco Boi, Michele Bianchi, Gabriela Graziani, Alessandro Gambardella, Matteo Berni, Monica De Carolis, Gianluca Carnevale, and Gabriela Graziani, Matteo Berni, Alessandro Gambardella, Monica De Carolis, Maria Cristina Maltarello, Marco Boi, Gianluca Carnevale, Michele Bianchi

Subjects
Materials science, Annealing (metallurgy), chemistry.chemical_element, Bioengineering, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Apatite, Biomaterials, Contact angle, Pulsed electron deposition, Crystallinity, Coated Materials, Biocompatible, Biomimetic Materials, Spectroscopy, Fourier Transform Infrared, Alloys, Cell Adhesion, Thin film, Bone regeneration, Titanium, Calcium phosphates, Ion-substituted hydroxyapatite, Pulsed electron deposition, Nanostructured coatings, Bone regeneration, Orthopedics, Mechanical Engineering, Titanium alloy, Prostheses and Implants, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, Orthopedics, Durapatite, chemistry, Chemical engineering, Calcium phosphates, Ion-substituted hydroxyapatite, Mechanics of Materials, visual_art, visual_art.visual_art_medium, Nanostructured coatings, Materials Science (all), 0210 nano-technology, Hydrophobic and Hydrophilic Interactions
Abstract

Biomimetic bone apatite coatings were realized for the first time by the novel Ionized Jet Deposition technique. Bone coatings were deposited on titanium alloy substrates by pulsed electron ablation of deproteinized bovine bone shafts in order to resemble bone apatite as closely as possible. The composition, morphology and mechanical properties of the coatings were characterized by GI-XRD, FT-IR, SEM-EDS, AFM, contact angle measurements, micro-scratch and screw-insertion tests. Different post-treatment annealing conditions (from 350 °C to 425 °C) were investigated. Bone apatite coatings exhibited a nanostructured surface morphology and a composition closely resembling that of the deposition target (i.e. natural bone apatite), also regarding the presence of magnesium and sodium ions. Crystallinity and composition of the coatings were strongly influenced by annealing temperature and duration; in particular, upon annealing at 400 °C and above, a crystallinity similar to that of bone was achieved. Finally, adhesion to the titanium substrate and hydrophilicity were significantly enhanced upon annealing, all characteristics being known to have a strong positive impact on promoting host cells attachment, proliferation and differentiation.

Published
2018

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