Author: "Lin, Jinguan" / Topic: cafs - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Lin, Jinguan" Topic cafs

Author: Tan, Shiming, Yang, Yiqing, Yang, Wenjuan, Han, Yaqian, Huang, Lisheng, Yang, Ruiqian, Hu, Zifan, Tao, Yi, Liu, Lin, Li, Yun, Oyang, Linda, Lin, Jinguan, Peng, Qiu, Jiang, Xianjie, Xu, Xuemeng, Xia, Longzheng, Peng, Mingjing, Wu, Nayiyuan, Tang, Yanyan, Cao, Deliang, Liao, Qianjin, and Zhou, Yujuan
Published: 2023
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Author: Tan, Shiming, Xia, Longzheng, Yi, Pin, Han, Yaqian, Tang, Lu, Pan, Qing, Tian, Yutong, Rao, Shan, Oyang, Linda, Liang, Jiaxin, Lin, Jinguan, Su, Min, Shi, Yingrui, Cao, Deliang, Zhou, Yujuan, and Liao, Qianjin
Subjects: TUMOR microenvironment, EXTRACELLULAR vesicles, MICRORNA, NUCLEIC acids, TUMOR growth
Abstract: Tumor microenvironment (TME) is the internal environment in which tumor cells survive, consisting of tumor cells, fibroblasts, endothelial cells, and immune cells, as well as non-cellular components, such as exosomes and cytokines. Exosomes are tiny extracellular vesicles (40-160nm) containing active substances, such as proteins, lipids and nucleic acids. Exosomes carry biologically active miRNAs to shuttle between tumor cells and TME, thereby affecting tumor development. Tumor-derived exosomal miRNAs induce matrix reprogramming in TME, creating a microenvironment that is conducive to tumor growth, metastasis, immune escape and chemotherapy resistance. In this review, we updated the role of exosomal miRNAs in the process of TME reshaping. [ABSTRACT FROM AUTHOR]
Published: 2020
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