Search

Introduction: Mild traumatic brain injury (mild TBI) exhibited abnormal brain network topologies associated with cognitive dysfunction. However, it was still unclear which aspects of network organi...

Some patients after mild traumatic brain injury (mTBI) experience microstructural damages in the long-distance white matter (WM) connections, which disrupts the functional connectome of large-scale brain networks that support cognitive function. Patterns of WM structural damage following mTBI were well documented using diffusion tensor imaging (DTI). However, the functional organization of WM and its association with gray matter functional networks (GM-FNs) and its DTI metrics remain unknown. The present study adopted resting-state functional magnetic resonance imaging to explore WM functional properties in mTBI patients (108 acute patients, 48 chronic patients, 46 healthy controls [HCs]). Eleven large-scale WM functional networks (WM-FNs) were constructed by the k-means clustering algorithm of voxel-wise WM functional connectivity (FC). Compared with HCs, acute mTBI patients observed enhanced FC between inferior fronto-occipital fasciculus (IFOF) WM-FN and primary sensorimotor WM-FNs, and cortical primary sensorimotor GM-FNs. Further, acute mTBI patients showed increased DTI metrics (mean diffusivity, axial diffusivity, and radial diffusivity) in deep WM-FNs and higher-order cognitive WM-FNs. Moreover, mTBI patients demonstrated full recovery of FC and partial recovery of DTI metrics in the chronic stage. Additionally, enhanced FC between IFOF WM-FN and anterior cerebellar GM-FN was correlated with impaired information processing speed. Our findings provide novel evidence for functional and structural alteration of WM-FNs in mTBI patients. Importantly, the convergent damage of the IFOF network might imply its crucial role in our understanding of the pathophysiology mechanism of mTBI patients.

Mild traumatic brain injury (mTBI) is the most prevalent neurological insult and leads to long-lasting cognitive impairment. Neuroimaging studies have discovered abnormalities in brain network connectivity following mTBI as the underlying neural basis of cognitive deficits. However, the pathophysiologic mechanisms involved in imaging alterations remain elusive. Proteins neuron-specific enolase (NSE) and ubiquitin C terminal hydrolase 1 are reliable markers for neuronal cell-body damage, both of which have been demonstrated to be increased in serum following mTBI. Therefore, we conducted a longitudinal study to examine relationships between abnormal brain network connectivity and serum neuronal biomarkers and their associations with cognitive recovery following mTBI. Sixty patients were followed-up at 1 week and 3 months post-injury and 41 controls were recruited. Resting-state functional magnetic resonance imaging was used to build a functional connectivity matrix within large-scale intrinsic networks, and their topological properties were analyzed using graph theory measures. We found that, compared with controls, mTBI patients showed significant decreases in a number of nodal characteristics in default mode network (DMN), salience network, and executive network (

This is the peer reviewed version of the following article: [ Yang, X, López-Grimau, V, Vilaseca, M, et al. Reuse of textile wastewater treated by moving bed biofilm reactor coupled with membrane bioreactor. Coloration Technol. 2021; 137: 484– 492. https://doi.org/10.1111/cote.12543], which has been published in final form at https://doi.org/10.1111/cote.12543. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. A laboratory-scale pilot plant of moving bed biofilm reactor coupled with membrane bioreactor (MBBR-MBR) was studied with regard to wastewater treatment in the textile industry, and the reuse feasibility of treated water was investigated. The pilot plant comprised two connected parts: an aerobic tank filled with carriers and a submerged membrane tank. The MBBR-MBR system reduced the hydraulic retention time to 1 day, which is very promising compared with conventional biological treatment in the textile industry. The removal efficiency of chemical oxygen demand reached 93%, which is almost the maximum for a biological process treating this type of wastewater, as well as the colour removal performance, which achieved 85%. Additionally, 99% of total suspended solids were removed due to filtration. Furthermore, new dyeing processes reusing the treated water were performed. The quality of the new dyed fabrics with treated water was compared with reference fabrics. Colour differences between new dyed fabrics and reference fabrics were found to be within the general requirement of the textile industry (¿ECMC(2:1) < 1). The reuse of treated water in new dyeing processes is beneficial both for the industry and for the environment, because the textile sector is an intensive water consumer during both the dyeing and finishing processes. This study is co-funded by ACCIÓ (Generalitat de Catalunya) within the REGIREU Project (COMRDI16-1-0062).

Deficits in information processing speed (IPS) are among the earliest and most prominent cognitive manifestations in mild traumatic brain injury (mTBI). We investigated the impact of white matter fiber location on IPS outcome in an individual basis assessment. A total of 112 acute mild TBI with all CT negative underwent brain DTI and blood sampling for inflammation cytokines within 7 days postinjury and 72 age‐ and sex matched healthy controls with same assessments were enrolled. IPS outcome was assessed by the trail making test at 6–12 month postinjury in mild TBI. Fractional anisotropy (FA) features were extracted using a novel lesion‐load analytical strategy to capture spatially heterogeneous white matter injuries and minimize implicit assumptions of uniform injury across diverse clinical presentations. Acute mild TBI exhibited a general pattern of increased and decreased FA in specific white matter tracts. The power of acute FA measures to identify patients developing IPS deficits with 92% accuracy and further improved to 96% accuracy by adding inflammation cytokines. The classifiers predicted individual's IPS and working memory ratings (r = .74 and .80, respectively, p, Combination of inflammation cytokine and fibers projecting to frontal cortex as predictors can identify long‐term information processing speed deficits in mild TBI patients with negative CT.

Accurate three-phase identification from Solid Oxide Fuel Cell (SOFC) anode micrograph is challenged by both noise and intensity inhomogeneity. In this paper, a novel framework is proposed for porous Ni-YSZ cermet anode Optical Microscopy (OM) image segmentation. The proposed framework takes advantage of a statistical model in which an observed image is decomposed into two multiplicative components (bias field and true image) and one additive component (noise). A two-stage Principal Component Analysis with Local Pixel Grouping (LPG-PCA) denoising algorithm is firstly performed to suppress additive noise, it can preserve more image local structural features by modeling a pixel and its nearest neighbors as a vector variable and selecting training samples with similar contents to this variable in a local window for PCA transformation. In order to enhance the robustness to noise, uneven illumination and other outliers, a kernel metric is introduced into fuzzy clustering method embedded with bias field correction for image segmentation. The proposed method has been compared to other state-of-the-art segmentation algorithms on both simulated images and real SOFC anode OM images. Extensive experiments results have demonstrated that the proposed framework can successfully eliminate the influence of both uneven illumination and noise on real Ni/YSZ anode OM images to obtain a better three-phase identification accuracy. The high-quality segmentation results lay firm foundation for accurate microstructural parameter extraction.

Background:The abuse of methamphetamine (MA) worldwide has gained international attention as the most rapidly growing illicit drug problem. The classification and treatment response prediction of MA addicts are thereby paramount, in order for effective treatments to be more targeted to individuals. However, there has been limited progress.Methods:In the present study, 43 MA-dependent participants and 38 age- and gender-matched healthy controls were enrolled, and their resting-state functional magnetic resonance imaging data were collected. MA-dependent participants who showed 50% reduction in craving were defined as responders to treatment. The present study used the machine learning method, which is a support vector machine (SVM), to detect the most relevant features for discriminating and predicting the treatment response for MA-dependent participants based on the features extracted from the functional graph metrics.Results:A classifier was able to differentiate MA-dependent subjects from normal controls, with a cross-validated prediction accuracy, sensitivity, and specificity of 73.2% [95% confidence interval (CI) = 71.23–74.17%), 66.05% (95% CI = 63.06–69.04%), and 80.35% (95% CI = 77.77–82.93%), respectively, at the individual level. The most accurate combination of classifier features included the nodal efficiency in the right middle temporal gyrus and the community index in the left precentral gyrus and cuneus. Between these two, the community index in the left precentral gyrus had the highest importance. In addition, the classification performance of the other classifier used to predict the treatment response of MA-dependent subjects had an accuracy, sensitivity, and specificity of 71.2% (95% CI = 69.28–73.12%), 86.75% (95% CI = 84.48–88.92%), and 55.65% (95% CI = 52.61–58.79%), respectively, at the individual level. Furthermore, the most accurate combination of classifier features included the nodal clustering coefficient in the right orbital part of the superior frontal gyrus, the nodal local efficiency in the right orbital part of the superior frontal gyrus, and the right triangular part of the inferior frontal gyrus and right temporal pole of middle temporal gyrus. Among these, the nodal local efficiency in the right temporal pole of the middle temporal gyrus had the highest feature importance.Conclusion:The present study identified the most relevant features of MA addiction and treatment based on SVMs and the features extracted from the graph metrics and provided possible biomarkers to differentiate and predict the treatment response for MA-dependent patients. The brain regions involved in the best combinations should be given close attention during the treatment of MA.

INTRODUCTION The objective of this study was to evaluate the impact of operative timing on outcomes of acute appendicitis. METHODS This study examined adult patients who had presented to the hospital with acute appendicitis and had undergone appendectomy from December 2017 to February 2019. Time delay and outcomes of perforated and non-perforated appendicitis were compared. Patients were classified into five groups based on the period from symptom onset to operation: group 1

Key roles of the gut–brain axis in brain injury development have been suggested in various mouse models; however, little is known about its functional significance in human mild traumatic brain injury (TBI). Here, we decipher this axis by profiling the gut microbiota in 98 acute mild TBI patients and 62 matched controls, and subgroup of them also measured circulating mediators and applied neuroimaging. Mild TBI patients had increased α-diversity and different overall microbial compositions compared with controls. 25-microbial genus classifiers distinguish patients from controls with an area under the receiver operating characteristic curve (AUC) of 0.889, while adding serum mediators and neuroimaging features further improved performance even in a small sample size (AUC = 0.969). Numerous correlations existed between gut bacteria, aberrant cortical thickness and cerebrovascular injury. Co-occurrence network analysis revealed two unique gut–brain axes in patients: 1) altered intestinalLachnospiraceae_NK4A136_groupandEubacterium_ruminantium_group-increased serum GDNF-subcallosal hypertrophy and cerebrovascular injury; 2) decreased intestinalEubacterium_xylanophilum_group–upregulated IL-6–thinned anterior insula. Our findings provide a new integrated mechanistic understanding and diagnostic model of mild TBI.

This study proposes an adaptive fault line detection method based on the improved singular value decomposition (SVD) de-noising and ideal clustering curve for distribution networks. First, the improved SVD algorithm is introduced to obtain the pure transient zero sequence current. Then, the fast Fourier transformation is employed to analyse the baseband signal and calculate the phase differences. After that, if the difference values are larger than the set threshold, the detection method based on the improved SVD and ideal clustering curve of baseband components is proposed; if not, the 1/4 cycle damping non-periodic components are rearranged, then based on the first half waveform extreme values and the rearranging damping non-periodic components, the detection method based on the ideal clustering curve of damping components is introduced. The simulation results prove the correctness of proposed selection method. After comparing with the existing methods, the advantages of proposed method are confirmed.

A hybrid Moving Bed Biofilm Reactor—Membrane Bioreactor (MBBR-MBR) was developed for the treatment of wastewater from a Spanish textile company. Compared with conventional activated sludge (CAS) treatment, the feasibility of this hybrid system to reduce economic and environmental impact on an industrial scale was conducted. The results showed that, technically, the removal efficiency of COD, TSS and color reached 93%, 99% and 85%, respectively. The newly dyed fabrics performed with the treated wastewater were qualified under the standards of the textile industry. Economically, the values of Capital Expenditure (CAPEX) calculated for the hybrid MBBR-MBR system are profitable because of the reduction in Operational Expenditure (OPEX) when compared with CAS treatment, due to the lower effluent discharge tax thanks to the higher quality of the effluent and the decolorizing agent saved. The result of Net Present Value (NPV) and the Internal Rate of Return (IRR) of 18% suggested that MBBR-MBR is financially applicable for implantation into the industrial scale. The MBBR-MBR treatment also showed lower environmental impacts than the CAS process in the life cycle assessment (LCA) study, especially in the category of climate change, thanks to the avoidance of using extra decolorizing agent, a synthetic product based on a triamine. This study is co-funded by ACCIÓ (Generalitat de Catalunya, Spain) within the REGIREU Project (COMRDI16-1-0062). The preliminary results of this study were presented at the II International Congress on Water and Sustainability, 24–26 March 2021, Terrassa, Barcelona, Spain. This work was selected by the scientific committee to assume the article processing charges (APC) of publishing it in an open access journal. Peer Reviewed Objectius de Desenvolupament Sostenible::6 - Aigua Neta i Sanejament Objectius de Desenvolupament Sostenible::9 - Indústria, Innovació i Infraestructura

Seroma is a virtually unavoidable early sequela after TEP hernioplasty. This randomised controlled trial evaluated the outcomes of preperitoneal closed-system suction drainage in laparoscopic totally extraperitoneal (TEP) hernioplasty for inguinal hernia. Ninety patients aged 18–80 years who presented to our hospital between May 2016 and February 2017 with primary unilateral inguinal hernia were randomised into the preperitoneal drain and no-drain groups. The primary outcome was seroma size on postoperative day 6. Secondary outcomes included clinical seroma formation and seroma size on day 1, day 6, 1 and 7 months postoperatively, length of postoperative stay, pain score, and recurrence. There was no significant difference in age, sex, co-morbidities, hernia side, mean hernia size, operating time, fixation adjuncts, or postoperative stay. The overall incidence of clinical seroma formation was 25.6% on postoperative day 1, 60.3% on postoperative day 6, 13.2% 1 month and 0% 7 months postoperatively. The mean drain output was 57.9 ml. The drain group had significantly fewer patients with seroma on day 1 (6 vs 14, p = 0.022) and day 6 (17 vs 30, p = 0.000), and a smaller mean seroma size on days 1 and 6 (p = 0.000). Subgroup analysis showed that sac ligation versus reduction, peritoneal perforation, and fixation adjuncts had no significant effects on seroma formation or size. There is a trend of lower early post-operation VAS score and more urinary retention in drain group was observed but not reaching statistical significance. No differences in postoperative pain score or complications were observed at 1 and 7 months’ post operation. Preperitoneal drainage for 23 h after laparoscopic TEP hernioplasty for inguinal hernia can effectively decrease seroma formation in the early postoperative period, and potentially improving postoperative pain. The benefit is short-term and no significant difference was demonstrated after 1-month post operations. This tradition technique applied to novel operative repair of inguinal hernia is safe and feasible with no significant morbidity demonstrated. Preperitoneal drainage after TEP can be considered as an option to improve patient satisfactions and recovery in selected patient group for maximal benefit, especially for those with prolonged operation which may associate with higher chance of seroma formation.

Membrane bioreactor (MBR) is one of the advanced treatment technologies used in industrial wastewater treatment due to its various advantages over conventional biological processes. Recently, the application of MBR in treatment of textile wastewater has increased significantly with an effective removal of contaminants. Moving bed bioreactor (MBBR) has been efficiently used for the treatment of different municipal and industrial wastewater during the last decades and it is a relatively novel and effective technology applied in textile wastewater treatment. This review paper presents the situation of MBR and MBBR technology for textile wastewater purification under different conditions and collates results of previous studies during the past years about MBR and MBBR treatment technologies used in textile processes. Both of these two technologies have shown their efficiency, but they still have problems in textile wastewater treatment. To this end, MBR-MBBR hybrid system could be an attractive solution for textile wastewater purification because of the high efficiency and low consumption of energy and space

In this study, three different biological methods&mdash, a conventional activated sludge (CAS) system, membrane bioreactor (MBR), and moving bed biofilm reactor (MBBR)&mdash, were investigated to treat textile wastewater from a local industry. The results showed that technically, MBR was the most efficient technology, of which the chemical oxygen demand (COD), total suspended solids (TSS), and color removal efficiency were 91%, 99.4%, and 80%, respectively, with a hydraulic retention time (HRT) of 1.3 days. MBBR, on the other hand, had a similar COD removal performance compared with CAS (82% vs. 83%) with halved HRT (1 day vs. 2 days) and 73% of TSS removed, while CAS had 66%. Economically, MBBR was a more attractive option for an industrial-scale plant since it saved 68.4% of the capital expenditures (CAPEX) and had the same operational expenditures (OPEX) as MBR. The MBBR system also had lower environmental impacts compared with CAS and MBR processes in the life cycle assessment (LCA) study, since it reduced the consumption of electricity and decolorizing agent with respect to CAS. According to the results of economic and LCA analyses, the water treated by the MBBR system was reused to make new dyeings because water reuse in the textile industry, which is a large water consumer, could achieve environmental and economic benefits. The quality of new dyed fabrics was within the acceptable limits of the textile industry.

Mesh infection after large incisional ventral hernia repair is a clinical dilemma in abdominal wall hernia surgery. It is believed foreign material should be removed but it causes secondary trauma to the abdominal wall tissue and might be associated with a higher risk of complications. Currently, there is no consensus on mesh-preservation treatment in cases of mesh infection after hernia repair in general. Herein we present the case of a 27-year-old male who recovered well from mesh infection after large incisional ventral hernia repair by mesh-preservation approach. The path to success is choice of material of prosthetic mesh; surgical approach of hernia repair, sufficient wound irrigation and drainage, and acquiring sterility of the mesh surface by wound care techniques such as local iodophor packing and vacuum sealing drainage. Clinical cohorts are needed to verify the feasibility of mesh-preservation treatment of mesh infection after large incisional hernia repair.

In response to a recent 500kV line shunt reactor high-voltage bushing failure event in a station, This article examines and analyzes the objects and protection actions after the casing is disassembled. It was found that the cause of the casing failure was caused by the arc igniting the insulating oil in the casing after the main insulation of the casing was discharged. Finally, corresponding preventive measures are proposed from the perspective of on-site operation and maintenance.

Aimed at solving the problem of the end shield fault of 500 kV capacitive bushing which happened frequently in the main power grid in recent time, two faults are taken as examples to analyze the fault characteristics and reasons of the spring cap type end shield devices. On that basis, effective revention measures and modification schemes for the spring cap type end shield devices of 500 kV capacitive bushing are proposed from perspectives of the equipment security operation and maintenance, and personal safety.

In recent years, with the development and construction of the power grid system, the porcelain column circuit breaker has been popularized and applied in the 500kV substation. However, in the actual operation and maintenance process, the leakage of oil has been found in the grading capacitor. The disassemble of an oil leakage grading capacitor of a 500kV porcelain column circuit breaker is analyzed in this paper. Through carrying out the sealing test; the insulation performance test; salt spray test and simulation test. At the same time, by comparing the sealing ring and cover plate material; calculating the potential difference of the cover plate and researching electrochemical corrosion factors. We can come to an conclusion that the cause of a suspected the grading capacitor oil leakage is the oil accumulation; and the main reason for the oil leakage problem of the grading capacitor is the electrochemical corrosion phenomenon on the sealing cover plate. Finally, on the basis of the reasons, the relevant rectification measures are put forward.

This paper analyzes the cause of a 500kV gapless MOA fault in a substation. The appearance inspection and disassembly analysis of the arrester are carried out. Combined with the protection action, the fault cause of the arrester is analyzed. It is found that the fault is caused by the side flashover failure of the local resistor piece of the line arrester due to the steepness of the lightning invasion wave is large. When the line is reclosed, the lower section bears the over-voltage, resulting in the damage of some resistors, and then causes the pressure release. Based on the analysis the paper puts forward some corresponding operation and maintenance measures.

Coronary microembolization (CME) occurs when atherosclerotic plaque debris is detached during the treatment of acute coronary syndrome with Percutaneous Coronary Intervention (PCI). The complications of distal microvascular embolism, including local myocardial inflammation, are the main causes of myocardial damage and are a strong predictor of poor long-term prognosis and major cardiac adverse events. microRNAs (miRNAs) are involved in the pathophysiological processes of cardiovascular inflammatory diseases. Dysregulation of microRNA (miR)-26a-5p, in particular, is associated with a variety of cardiovascular diseases. However, the role of miR-26a-5p in CME-induced myocardial injury is unclear. In this study, we developed an animal model of CME by injecting microembolic balls into the left ventricle of rats and found that miR-26a-5p expression decreased in myocardial tissue in response. Using a miR-26a-5p mimic, echocardiography, hematoxylin-eosin staining, and Western blot analysis we found that the diminished cardiac function and myocardial inflammation induced by CME is alleviated by miR-26a-5p overexpression. Furthermore, our results show that inhibitors of miR-26a-5p have the opposite effect. In addition, in vitro experiments using real-time PCR, Western blot analysis, and a dual luciferase reporter gene show that HMGA1 is a target gene of miR-26a-5p. Thus, overexpression of miR-26a-5p could be a novel therapy to improve CME-induced myocardial damage.

To explore the correlation of MIR17HG polymorphism with susceptibility and prognosis of multiple myeloma (MM).A total of 217 MM patients treated with high-dose melphalan combined with autologous peripheral blood stem-cell transplantation at our hospital were enrolled as the case group, and 220 healthy people were included as the control group. Sequenom MassARRAY iPLEX Gold single nucleotide polymorphism genotyping was used to detect polymorphisms of MIR17HG, including rs7336610, rs17735387, rs4284505, and rs1428.An increased risk of MM was found in patients who carried the rs7336610 T allele and rs4284505 G allele, and the higher the Durie-Salmon and International Staging System stages were, the more MM patients carrying rs7336610 CT + TT genotype and rs4284505 AG + GG genotype (all P .05). Haplotype AC (rs4284505-rs1428) and CA (rs7336610-rs4284505) evidently reduce MM risk, whereas haplotype GC (rs4284505-rs1428) significantly elevated MM risk (all P .05). Kaplan-Meier curve analysis demonstrated that rs7336610 CC genotype carriers had higher 5-year survival rate than CT + TT genotype carriers (P = .034), and the AA genotype carriers of rs4284505 had higher 5-year survival rate than AG + GG genotype carriers (P .001).Polymorphisms of MIR17HG rs7336610 and rs1428 were correlated with MM risk and prognosis.

Biodiversity loss and variation in species responses to climate and land use change have been found across broad taxonomic groups. However, whether species from the same taxonomic group with distinct geographical ranges will respond differently is poorly understood. The aim of this study is to predict the potential impacts of future climate and land use change on the distribution of narrow- and wide-ranging Rhododendron species, and estimate their relative contribution in China. We applied the presence-only ecological niche model MaxEnt to predict the distribution of 10 narrow-ranging and 10 wide-ranging Rhododendron species for the year 2070, using three general circulation models and three scenarios of climate and land use change. We measured the predicted distribution change of each species using change ratio, distance and direction of core range shifts, and niche overlap using Schoener's D. We found that the distribution areas of six narrow-ranging species would decrease, of which one species would go extinct. The remaining four narrow-ranging species would experience range expansion. Distribution of all the wide-ranging Rhododendron species would decrease. All Rhododendrons will shift to the northwest. We conclude that Rhododendron species generally will be negatively affected by the climatic and land use change expected in 2070 from the three scenarios evaluated in this study, but some narrow-ranging species may be positively influenced. Narrow-ranging Rhododendron species are more vulnerable compared to wide-ranging Rhododendron species. This study demonstrated that the effects of climate and land use change on alpine and subalpine plant species is species-specific, thereby strengthening our understanding of the impacts of climate and land use change on plant distribution.

CFS digital signature algorithm, which proposed in 2001, is the most important code based digital signature algorithm and can resist the known attack of quantum algorithms. But the efficiency of CFS is very low because of the extremely low signing speed and the large public key size. In this paper, a variation of CFS algorithm is presented. Instead of the Goppa code and the Patterson decoding algorithm, the new algorithm selects the Quasi-Cyclic Low Density Parity Check (QC-LDPC) code and the Belief Propagation (BP) decoding algorithm in the signing process. Compared with CFS algorithm, the new algorithm greatly reduces the storage space of public key and improves the efficiency of signature without compromising the security.

Laparoscopic low anterior resection (LAR) with sphincter preservation for ultra-low rectal cancer is always a challenging operation in colorectal surgery. To achieve negative margins, reducing the difficulty and risks of the procedure are major goals for us. The marker meeting approach we reported can help to accomplish this goal. The key technique for the marker meeting approach is to ensure a clear distal margin in a low resection of the rectum by transanal dissection. This procedure allows access to the space around the distal rectum and mesorectum and to pack the gauzes in the distal part of the space as a landmark. Routine laparoscopic LAR was performed to dissect the space until reaching the gauzes packed above and achieve complete mobilization of the rectum and mesorectum. This surgical procedure is simpler and reduces the difficulty of the operation. Therefore, it is expected to reduce the risk of surgery-related complications and positive margins and is suitable to be widely applied and extended in clinical practice. The short-term and long-term clinical outcomes of the marker meeting approach need more research in large samples.

Summary This paper studies the problems of stabilization of discrete-time linear systems with a single input delay. By developing the methodology of pseudo-predictor feedback, which uses the (artificial) closed-loop system dynamics to predict the future state, memoryless state feedback control laws are constructed to solve the problem. Necessary and sufficient conditions are obtained to guarantee the stability of the closed-loop system in terms of the stability of a class-difference equations. It is also shown that the proposed controller achieves semi-global stabilization of the system if its actuator is subject to either magnitude saturation or energy constraints under the condition that the open-loop system is only polynomially unstable. Numerical examples have been worked out to illustrate the effectiveness of the proposed approaches. Copyright © 2015 John Wiley & Sons, Ltd.

Ethnopharmacological relevance Herbal teas have long been consumed by Chinese people for preventive and/or therapeutic healthcare. Although herbal teas are widely consumed by many cultural groups in different regions of China, no thorough review has been undertaken to assess the diversity of the country's herbal tea usage. This literature review, complemented by a quantitative survey in an important tea market in Kunming, begins to fill this knowledge gap. Aims of the study The study aims to summarize the current knowledge of plant species used as herbal teas by different cultural groups in different regions of China, with a focus on the teas’ perceived traditional healthcare functions, related phytochemical/pharmaceutical research, and safety issues. Materials and methods The study involved a comprehensive literature review and a market survey. The literature review was based on published ethnobotanical studies of herbal teas in China. We searched the Web of Science™, ELSEVIER, the China National Knowledge Infrastructure (CNKI) and the China Science and Technology Journal Database to locate relevant studies (including journal articles, Masters/PhD dissertations and books) that were published before March 2017. A species list was compiled based on the review and supplemented with information retrieved from the Scifinder database ( https://scifinder.cas.org ) and the Chinese Pharmacopoeia (2010). A Use Value Index was employed for ranking the most cited species. Based on the 29 most cited species, we discussed the current research status in relation to healthcare benefits and safety concerns of herbal teas in China. To better understand the current status of the herbal tea market in China, we also surveyed 136 tea vendors at the Xiongda Tea Market in Kunming. Information gathered from the survey included the species sold, the sale prices and the form of the herbal tea product. Results The literature identified 759 plant species used as herbal tea in China and the market survey identified an additional 23 species. Most of the species used were from the Leguminosae, Compositae and Lamiaceae families. Twenty two provinces and fourteen ethnic minority groups have records on the consumption of herbal teas. Southern China uses up to 82% of the total species, and 211 out of 759 species are used by minority groups. Thirty categories of traditional healthcare functions are linked with herbal teas, with clearing away heat, relieving toxicity and suppressing cough being the most important functions. There is phytochemical/pharmaceutical evidence to support the claimed healthcare benefits of some Chinese herbal teas. Although Chinese herbal teas are generally safe to consume, overdoses of some herbal teas and some unapproved mixtures of species may cause health risks. Based on our market survey, the prices of most herbal teas range between 100 and 200 RMB (US$15–30) per kg. Conclusions A rich array of herbal tea species with various traditional healthcare functions have long been used in China, and as such there is a huge market potential for Chinese herbal teas. More pharmaceutical/phytochemical research is needed to assess a wide range of perceived healthcare benefits of Chinese herbal teas. Our research highlights the need to study herbal teas through an ethnopharmacological perspective and by employing a holistic approach, which requires greater consideration of traditional knowledge in the pharmacological research design. Product safety and sustainability issues should also be considered, so the traditional applications of herbal teas can be transformed to efficient health boosting functional products.

Biodiversity-ecosystem functioning (BEF) research has extended its scope from communities that are short-lived or reshape their structure annually to structurally complex forest ecosystems. The establishment of tree diversity experiments poses specific methodological challenges for assessing the multiple functions provided by forest ecosystems. In particular, methodological inconsistencies and nonstandardized protocols impede the analysis of multifunctionality within, and comparability across the increasing number of tree diversity experiments. By providing an overview on key methods currently applied in one of the largest forest biodiversity experiments, we show how methods differing in scale and simplicity can be combined to retrieve consistent data allowing novel insights into forest ecosystem functioning. Furthermore, we discuss and develop recommendations for the integration and transferability of diverse methodical approaches to present and future forest biodiversity experiments. We identified four principles that should guide basic decisions concerning method selection for tree diversity experiments and forest BEF research: (1) method selection should be directed toward maximizing data density to increase the number of measured variables in each plot. (2) Methods should cover all relevant scales of the experiment to consider scale dependencies of biodiversity effects. (3) The same variable should be evaluated with the same method across space and time for adequate larger-scale and longer-time data analysis and to reduce errors due to changing measurement protocols. (4) Standardized, practical and rapid methods for assessing biodiversity and ecosystem functions should be promoted to increase comparability among forest BEF experiments. We demonstrate that currently available methods provide us with a sophisticated toolbox to improve a synergistic understanding of forest multifunctionality. However, these methods require further adjustment to the specific requirements of structurally complex and long-lived forest ecosystems. By applying methods connecting relevant scales, trophic levels, and above- and belowground ecosystem compartments, knowledge gain from large tree diversity experiments can be optimized. Biodiversity–ecosystem functioning (BEF) research has extended its scope from communities that are short‐lived or reshape their structure annually to structurally complex forest ecosystems. The establishment of tree diversity experiments poses specific methodological challenges for assessing the multiple functions provided by forest ecosystems. In particular, methodological inconsistencies and nonstandardized protocols impede the analysis of multifunctionality within, and comparability across the increasing number of tree diversity experiments. By providing an overview on key methods currently applied in one of the largest forest biodiversity experiments, we show how methods differing in scale and simplicity can be combined to retrieve consistent data allowing novel insights into forest ecosystem functioning. Furthermore, we discuss and develop recommendations for the integration and transferability of diverse methodical approaches to present and future forest biodiversity experiments. We identified four principles that should guide basic decisions concerning method selection for tree diversity experiments and forest BEF research: (1) method selection should be directed toward maximizing data density to increase the number of measured variables in each plot. (2) Methods should cover all relevant scales of the experiment to consider scale dependencies of biodiversity effects. (3) The same variable should be evaluated with the same method across space and time for adequate larger‐scale and longer‐time data analysis and to reduce errors due to changing measurement protocols. (4) Standardized, practical and rapid methods for assessing biodiversity and ecosystem functions should be promoted to increase comparability among forest BEF experiments. We demonstrate that currently available methods provide us with a sophisticated toolbox to improve a synergistic understanding of forest multifunctionality. However, these methods require further adjustment to the specific requirements of structurally complex and long‐lived forest ecosystems. By applying methods connecting relevant scales, trophic levels, and above‐ and belowground ecosystem compartments, knowledge gain from large tree diversity experiments can be optimized.

This paper studies the delayed output feedback (DOF) of spacecraft three-axis magnetic attitude control system with actuator delays. By noticing that the linearized system of the magnetic attitude control system is a linear periodic one, the DOF controller is derived for general linear time-varying systems with actuator delays. Compared with other state controllers, the DOF controller only uses the past and present output and input signals, hence the problem that system states can't be measured completely is avoided naturally. For magnetic attitude control system, the time-varying feedback gain is designed under some sufficient and necessary conditions associated with the spacecraft parameters. Simulations are carried out to illuminate the effectiveness of the proposed controller.

Antibiotic administration, while facilitating clearance of targeted infections, also perturbs commensal microbial communities. Previous studies have all focused on the effects of short term use of antibiotics. Here, we focus on the effects of long term use of antibiotic on gut microbiota and immunity. BALB/c mice received saline or different doses of ceftriaxone sodium (100, 200 and 400 mg/mL) via daily gavage for 150 days. Alterations of fecal microbiota, small intestine histopathology, body weight, spleen index, serum IgG, mucus SIgA, IFN-γ/IL-4 ratio, CD4/CD8 ratio and CD4+CD25+ cells were evaluated. Long term ceftriaxone sodium administration resulted in gut microbiota dysbiosis, intestine histological lesions, growth inhibition, spleen index reducing. The immune defense ability reduced as serum IgG and mucus SIgA decreased significantly. Not only the immune defense, long term ceftriaxone administration also affected immune regulation. The IFN-γ/IL-4 and CD4/CD8 ratios increased, the CD4+CD25+ cells reduced on days 30 and 60 after ceftriaxone administration. However, after 90 days of ceftriaxone administration, the IFN-γ/IL-4, CD4/CD8 ratios and CD4+CD25+ cells restored, which indicated a new balance of immune regulation had been formed. Overall, these findings contribute to our understanding of long term antibiotic administration influencing gut microbiota and immunity.

Parastomal hernia is one of the most common long-term complications after abdominal ostomy. Surgical treatment for parastomal hernia is the only cure but a fairly difficult field because of the problems of infection, effects, complications and recurrence. Laparoscopic repair operations are good choices for Parastomal hernia because of their mini-invasive nature and confirmed effects. There are several major laparoscopic procedures for parastomal hernioplasty. The indications, technical details and complications of them will be introduced and discussed in this article.

Background Angioleiomyoma is an uncommon benign soft tissue tumor and originates from the vascular smooth muscle. It often causes pain and is rarely found in inguinal region. We present a rare case of inguinal canal angioleiomyoma of a female patient who suffered from right groin pain for 4 years and mimicking inguinal hernia clinically. Presentation of case A 53-year-old Chinese female patient presented with 4-year history of right groin pain which was exacerbated by movement. Magnetic resonance imaging was performed in view of atypical presentation and absence of cough impulse. Inguinal canal was subsequently explored by open approach and the mass was found arising from the posterior wall of the inguinal canal and measured 5.2 cm × 3.8 cm. The posterior wall was repaired by Bassini approach after the mass was resected en-bloc. Inguinal pain was resolved and no hernia was found during follow-up. Pathology of the resected specimen confirmed angioleiomyoma with clear resection margins. Conclusion This is the first report of a case of angioleiomyoma of the inguinal canal, which presents as a painful mass. Magnetic resonance imaging should be considered when presenting history and physical examination does not confirm with the diagnosis of inguinal hernia. After inguinal canal exploration, suture or mesh repair should be performed to prevent weakening of posterior wall leading to inguinal hernia.

Laparoscopic resection of gastric wall tumor is commonly performed nowadays. The exact surgical procedure was decided according to the location, size and morphology of the tumor. In this video, we performed a laparoscopic resection of a 5cm tumor located at distal posterior gastric wall near the greater curvature. Technical consideration was discussed.

The under-ground mushroom Tuber indicum is renowned for its economic, nutritional, ethnobotanical and ecological importance. For the development of sustainable harvest and conservation practices, better knowledge about the mushroom's habitat is indispensable. However, few approaches allow monitoring T. indicum's distribution on a large geographic scale. Apart from the difficulty to directly monitor them by Remote Sensing and GIS technology, a particular challenge arises from the sampling limitations for this seasonal mushroom. This problem is common in geology, where underground mineral resources must be mapped without direct observations. Geologists apply the 'Weights of Evidence' method for such situations, and this approach may have potential for underground mushrooms as well. We thus constructed potential habitat maps for T. indicum using the Weights of Evidence method. Based on field survey and published sources, ten influential indicators associated with T. indicum were selected and mapped for Longyang district in southwestern Yunnan, China. Two predictive models were established from independent environmental layers. In order to build better understanding of the models' predictive ability, apart from the Receiver Operating Characteristic (ROC) curve, the Area Adjusted Frequency (AAF) approach was also applied for model evaluation. For the final map, the best-performing model was selected. The resulting habitat map could provide guidance for future conservation activities. (C) 2012 Elsevier B.V. All rights reserved.

Laparoscopic repair of ventral incisional hernia with intraperitoneal onlay mesh (IPOM) technique by anti-adhesion mesh has been widely adopted. Due to clinical heterogenicity in location, quantity and size of abdominal incisional hernia, strategy of such repair can be challenging. We hereby present the video of a patient with multiple swiss-cheese hernias in a single long midline incision repaired with double anti-adhesion mesh by IPOM technique. Patient demographics, technical details and clinical tips & tricks are discussed.

Matsutake Trade in Yunnan Province, China: An Overview. Matsutake are economically important wild mushrooms that contribute greatly to rural livelihoods and local economies in many parts of the northern hemisphere. This paper provides an overview of the matsutake trade in Yunnan province, China, where increased attention is being given to the sustainable utilization of nontimber forest products. Topics covered include the distribution, production, and export of matsutake in Yunnan, and the market chain for matsutake in Yunnan, whereby matsutake are harvested from the wild and exported to Japan within 48 hours.

It is very hard to access cloud-free remote sensing data, especially for the ocean color images. A cloud removal approach from ocean color satellite images based on numerical modeling is introduced. The approach removes cloud-contaminated portions and then reconstructs the missing data utilizing model simulated values. The basic idea is to create the relationship between cloud-free patches and cloud-contaminated patches under the assumption that both of them are influenced by the same marine hydrodynamic conditions. Firstly, we find cloud-free GOCI (the Geostationary Ocean Color Imager) retrieved suspended sediment concentrations (SSC) in the East China Sea before and after the time of cloudy images, which are set as initial field and validation data for numerical model, respectively. Secondly, a sediment transport model based on COHERENS, a coupled hydrodynamic-ecological ocean model for regional and shelf seas, is configured. The comparison between simulated results and validation images show that the sediment transport model can be used to simulate actual sediment distribution and transport in the East China Sea. Then, the simulated SSCs corresponding to the cloudy portions are used to remove the cloud and replace the missing values. Finally, the accuracy assessments of the results are carried out by visual and statistical analysis. The experimental results demonstrate that the proposed method can effectively remove cloud from GOCI images and reconstruct the missing data, which is a new way to enhance the effectiveness and availability of ocean color data, and is of great practical significance.

The virtual test model method is proposed to solve airfoil structure visual monitoring problem. Static loading test is conducted to obtain the measured strain data; finite element software ANSYS and WORKBENCH are used to simulate airfoil 3D model and obtain the simulation strain data; virtual test model is constructed through fusing measured and simulation strain data by applying Bayes-Kriging method. This model transforms the health monitoring process of structure into a visual fluctuating process of spatial curved surface, which helps realize dynamic observation of the structure state. Structure state model graph is constructed through contrasting the virtual test model and the reference model of health conditioning, which could amplify the strain changes. Then the structure condition could be qualified by the features of model graph. Structure visual monitoring and condition qualification are both realized by the experiment, thus the method of visual test model is proved to be valid.

In the last 6 years China has introduced a number of policies to try and conserve forests and protect watershed integrity; these include a ban on commercial logging, reforestation projects, restrictions on upland farming and burning, and controls on livestock grazing. The blanket nature of these impositions when combined with rapid socio-economic changes have increased pressures on many small rural communities. In this paper, we examine the case of Jisha Village in northwestern Yunnan, China—a typical rural Tibetan community sustained by traditional agriculture and livestock management. The cessation of commercial logging has seen the community turn to towards other income streams such as non-timber forest products (NTFP), increased livestock and attempts to foster tourism. However, timber quotas together with new road access have spurred the development of unofficial markets for village firewood and enhanced access to nearby forests. In addition, the decline of bamboo—a traditional fencing material—has resulted in an estimated 35-fold increase in demand for pine wood. Wood demands in this community are swiftly exceeding the sustainable harvest levels. Forest loss does not merely represent the depletion or degradation of future village timber resources, but also the loss of NTFP habitat. Moreover, due to proscriptions on rangeland burning, pasturelands are becoming degraded and grazing in forests is more intensive—reducing forest regeneration. These findings support calls to improve the flexibility and incorporate local needs into forest policy—the problems highlighted here seem indicative of the practical and philosophical challenges facing environmental planning and research in China.

Matsutake (Tricholoma spp.) are a group of commercially important mushrooms that are increasingly threatened by over-collection. Ecologically sustainable management of matsutake has been hindered by the lack of essential information such as reliable distribution maps. Although a variety of spatial distribution models have been applied to map many different plants, this has rarely been attempted for mushrooms. In this study, we employed a logistic regression and a GIS expert system to model the fine-scale spatial distribution of matsutake in Yunnan southwest China Both models predicted mushroom habitat to an accuracy acceptable for resource management. The overall mapping accuracy of the GIS expert system was slightly better than the logistic regression model (70.37% versus 65.43%). Furthermore, unlike the logistic regression model, developing the GIS expert system required no field-based samples. This has important practical implications because it is very difficult to survey and sample mushrooms and other non-wood forest products (NWFP), which are usually inconspicuous species and/or lower plants. Therefore, when adequate samples are not available, incorporating local expert knowledge can help make better-informed management decisions and provide an affordable habitat identification tool. (c) 2006 Elsevier B.V. All rights reserved.

Background: With advances in oesophagogastroduodenoscopy (OGD), incidental finding of submucosal tumor (SMT) in upper gastrointestinal tract is increasingly reported. These lesions are usually small and the patients are generally asymptomatic, conservative management is commonly practiced before the era of endoscopic surgery. Nonetheless, with the rapid development in endoscopic instruments and techniques, endoscopic resection of SMT is frequently performed worldwide. We herein present a patient with endoscopic resection of an antral SMT. Method: A 68-year-old woman presented with upper abdominal pain for 3 months. Upper endoscopy showed a 3 cm SMT at the antero-superior part of the antrum. Endoscopic ultrasound and CT scan were performed and the preliminary diagnosis was gastric wall lipoma. Endoscopic resection of the SMT was performed and the procedure was described. Results: The operation was performed under general anesthesia uneventfully. The patient resumed fluid diet on the first post-operative day and was discharged on the fourth day after the procedure. Conclusions: Endoscopic resection of gastric SMT can be performed safely. This is as-sociated with quick recovery and definitive histopathological diagnosis can be obtained.