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1. Author Correction: Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study

Author

Rulli, Eliana, Quaranta, Luciano, Riva, Ivano, Poli, Davide, Hollander, Lital, Galli, Fabio, Katsanos, Andreas, Oddone, Francesco, Torri, Valter, Weinreb, N Varano L, Robert, Carchedi, T, Talarico, S, Frezzotti, P, Parravano, F, Motolese, I, Bagaglia, Sa, Rossi, Gcm, Lateri, S, Bossolesi, L, Carmassi, L, Rolle, T, Piccini, R, Ratiglia, R, Rossi, A, Gandolfi, S, Tagliavini, V, Ungaro, N, Fossarello, M, Cucca, A, Zucca, I, Uva, M, Bonacci, E, Cardarella, G, Tognetto, D, Vattovani, O, Vallon, P, Iannacone, F, Fontana, L, Marchi, S, Manni, Gl, Jannetta, D, Roberti, G, Rossetti, L, Maggiolo, E, Oneta, O, Sborgia, C, Cantatore, F, Mastropasqua, L, Agnifili, L, Campos, E, Gizzi, C, Giannaccare, G, Pucci, V, Cassamali, M, Costagliola, C, Traverso, C, Scotto, R, Musolino, M, Landi, L, Bagnis, A., Rulli, Eliana, Quaranta, Luciano, Riva, Ivano, Poli, Davide, Hollander, Lital, Galli, Fabio, Katsanos, Andrea, Oddone, Francesco, Torri, Valter, Weinreb, Robert, N Varano L, Carchedi, T, Talarico, S, Frezzotti, P, Parravano, F, Motolese, I, Bagaglia, Sa, Rossi, Gcm, Lateri, S, Bossolesi, L, Carmassi, L, Rolle, T, Piccini, R, Ratiglia, R, Rossi, A, Gandolfi, S, Tagliavini, V, Ungaro, N, Fossarello, M, Cucca, A, Zucca, I, Uva, M, Bonacci, E, Cardarella, G, Tognetto, D, Vattovani, O, Vallon, P, Iannacone, F, Fontana, L, Marchi, S, Manni, Gl, Jannetta, D, Roberti, G, Rossetti, L, Maggiolo, E, Oneta, O, Sborgia, C, Cantatore, F, Mastropasqua, L, Agnifili, L, Campos, E, Gizzi, C, Giannaccare, G, Pucci, V, Cassamali, M, Costagliola, C, Traverso, C, Scotto, R, Musolino, M, Landi, L, and Bagnis, A.

Subjects
Multidisciplinary, Open angle glaucoma, business.industry, Published Erratum, lcsh:R, MEDLINE, lcsh:Medicine, Italian Study Group on QoL in Glaucoma, Eye, Quality of life (healthcare), Medicine, Optometry, lcsh:Q, Visual field loss, business, lcsh:Science
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Published
2020

2. Vision-related quality of life and symptom perception change over time in newly-diagnosed primary open angle glaucoma patients

Author

Riva, I, Legramandi, L, Rulli, E, Konstas, Ag, Katsanos, A, Oddone, F, Weinreb, Rn, Quaranta, L, Varano, L, Carchedi, T, Talarico, S, Parravano, F, Motolese, I, Bagaglia, Sa, Rossi, Gcm, Lateri, S, Bossolesi, L, Carmassi, L, Rolle, T, Piccini, R, Ratiglia, R, Rossi, A, Gandolfi, S, Tagliavini, Ungaro, N, Fossarello, M, Cuccu, A, Zucca, I, Uva, M, Bonacci, E, Cardarella, G, Tognetto, D, Vattovani, O, Vallon, P, Iannacone, F, Fontana, L, Marchi, S, Manni, G, Iannetta, D, Roberti, G, Rossetti, L, Maggiolo, E, Oneta, O, Sborgia, C, Cantatore, F, Mastropasqua, L, Agnifili, L, Campos, E, Gizzi, C, Giannaccare, G, Pucci, Cassamali, M, Costagliola, C, Traverso, C, Scotto, R, Musolino, M, Landi, L, Bagnis, A, Riva I, Legramandi L, Rulli E, Konstas AG, Katsanos A, Oddone F, Weinreb RN, Quaranta L, Italian Study Group on QoL in Glaucoma: L Varano, T Carchedi, S Talarico, F Parravano, I Motolese, SA Bagaglia, GCM Rossi, S Lateri, L Bossolesi, L Carmassi, T Rolle, R Piccini, R Ratiglia, A Rossi, S Gandolfi, V Tagliavini, N Ungaro, M Fossarello, A Cuccu, I Zucca, M Uva, E Bonacci, G Cardarella, D Tognetto, O Vattovani, P Vallon, F Iannacone, L Fontana, S Marchi, GL Manni, D Jannetta, G Roberti, L Rossetti, E Maggiolo, O Oneta, C Sborgia, F Cantatore, L Mastropasqua, L Agnifili, E Campos, C Gizzi, G Giannaccare, V Pucci, M Cassamali, C Costagliola, C Traverso, R Scotto, M Musolino, L Landi, A Bagnis, Riva, Ivano, Legramandi, Lorenzo, Rulli, Eliana, Konstas, Anastasios G, Katsanos, Andrea, Oddone, Francesco, Weinreb, Robert N, Quaranta, Luciano, Varano, L, Carchedi, T, Talarico, S, Parravano, F, Motolese, I, Bagaglia, Sa, Rossi, Gcm, Lateri, S, Bossolesi, L, Carmassi, L, Rolle, T, Piccini, R, Ratiglia, R, Rossi, A, Gandolfi, S, Tagliavini, Ungaro, N, Fossarello, M, Cuccu, A, Zucca, I, Uva, M, Bonacci, E, Cardarella, G, Tognetto, D, Vattovani, O, Vallon, P, Iannacone, F, Fontana, L, Marchi, S, Manni, Gl, Jannetta, D, Roberti, G, Rossetti, L, Maggiolo, E, Oneta, O, Sborgia, C, Cantatore, F, Mastropasqua, L, Agnifili, L, Campos, E, Gizzi, C, Giannaccare, G, Pucci, Cassamali, M, Costagliola, C, Traverso, C, Scotto, R, Musolino, M, Landi, L, and Bagnis, A.

Subjects
0301 basic medicine, Change over time, medicine.medical_specialty, Aging, Visual acuity, Open angle glaucoma, genetic structures, Population, lcsh:Medicine, Glaucoma, Diseases, Italian Study Group on QoL in Glaucoma, Neurodegenerative, Eye, Article, 03 medical and health sciences, Medical research, 0302 clinical medicine, Quality of life, Clinical Research, Settore MED/30, Internal medicine, medicine, POAG, lcsh:Science, education, Prospective cohort study, Author Correction, Eye Disease and Disorders of Vision, education.field_of_study, Multidisciplinary, business.industry, lcsh:R, Neurosciences, medicine.disease, primary open angle glaucoma, humanities, eye diseases, 030104 developmental biology, Symptom perception, glaucoma, quality of life, lcsh:Q, sense organs, medicine.symptom, business, 030217 neurology & neurosurgery
Abstract

To evaluate the change over time of vision-related quality of life (QoL) and glaucoma symptoms in a population of newly-diagnosed primary open angle glaucoma (POAG) patients. Multicenter, prospective study. Consecutive newly-diagnosed POAG patients were enrolled and followed-up for one year. Follow-up visits were scheduled at 6 and 12 months from baseline. At each visit, vision-related QoL and glaucoma-related symptoms were assessed by the means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and the Glaucoma Symptom Scale (GSS), respectively. Trends over time for NEI-VFQ-25 and GSS scores were evaluated with longitudinal linear mixed models. One-hundred seventy-eight patients were included in the analysis. At baseline, early to moderate glaucoma stages were associated with higher scores for most GSS and NEI-VFQ-25 items, while lower best-corrected visual acuity was associated with lower scores for 4 of the 12 NEI-VFQ-25 items. During the follow-up, all the GSS scores, the NEI-VFQ-25 total score, and 7 of the 12 NEI-VFQ-25 scores significantly improved (p

Published
2019

3. Influence of Sociodemographic Factors on Disease Characteristics and Vision-related Quality of Life in Primary Open-angle Glaucoma Patients: The Italian Primary Open Angle Glaucoma Study (IPOAGS)

Author

Riva, Ivano, Legramandi, Lorenzo, Katsanos, Andreas, Oddone, Francesco, Rulli, Eliana, Roberti, Gloria, Quaranta Luciano, Varano L, Carchedi T, Talarico S, Parravano F, Motolese I, Bagaglia SA, Rossi GCM, Lateri S, Bossolesi L, Carmassi L, Rolle T, Piccini R, Ratiglia R, Rossi A, Gandolfi S, Tagliavini V, Ungaro N, Fossarello M, Cucca A, Zucca I, Uva M, Bonacci E, Cardarella G, Tognetto D, Vattovani O, Vallon P, Iannacone F, Fontana L, Marchi S, Manni GL, Jannetta D, Roberti G, Rossetti L, Maggiolo E, Oneta O, Sborgia C, Cantatore F, Mastropasqua L, Agnifili L, Campos E, Gizzi C, Giannaccare G, Pucci V, Cassamali M, Costagliola C, Scotto R, Musolino M, Landi L, Bagnis A., I Riva, L Legramandi, A Katsanos, F Oddone, E Rulli, G Roberti, L Quaranta, Italian Study Group on QoL in Glaucoma: L Varano, T Carchedi, S Talarico, F Parravano, I Motolese, SA Bagaglia, GCM Rossi, S Lateri, L Bossolesi, L Carmassi, T Rolle, R Piccini, R Ratiglia, A Rossi, S Gandolfi, V Tagliavini, N Ungaro, M Fossarello, A Cucca, I Zucca, M Uva, E Bonacci, G Cardarella, D Tognetto, O Vattovani, P Vallon, F Iannacone, L Fontana, S Marchi, GL Manni, D Jannetta, L Rossetti, E Maggiolo, O Oneta, C Sborgia, F Cantatore, L Mastropasqua, L Agnifili, E Campos, C Gizzi, G Giannaccare, V Pucci, M Cassamali, C Costagliola, C Traverso, R Scotto, M Musolino, L Landi, A Bagnis, Riva, Ivano, Legramandi, Lorenzo, Katsanos, Andrea, Oddone, Francesco, Rulli, Eliana, Roberti, Gloria, Quaranta, Luciano, Varano, L, Carchedi, T, Talarico, S, Parravano, F, Motolese, I, Bagaglia, Sa, Rossi, Gcm, Lateri, S, Bossolesi, L, Carmassi, L, Rolle, T, Piccini, R, Ratiglia, R, Rossi, A, Gandolfi, S, Tagliavini, V, Ungaro, N, Fossarello, M, Cucca, A, Zucca, I, Uva, M, Bonacci, E, Cardarella, G, Tognetto, D, Vattovani, O, Vallon, P, Iannacone, F, Fontana, L, Marchi, S, Manni, Gl, Jannetta, D, Roberti, G, Rossetti, L, Maggiolo, E, Oneta, O, Sborgia, C, Cantatore, F, Mastropasqua, L, Agnifili, L, Campos, E, Gizzi, C, Giannaccare, G, Pucci, V, Cassamali, M, Costagliola, C, Scotto, R, Musolino, M, Landi, L, and Bagnis, A.

Subjects
Male, medicine.medical_specialty, Multivariate statistics, Visual acuity, Open angle glaucoma, genetic structures, Cross-sectional study, sociodemographic factors, Visual Acuity, Glaucoma, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Internal medicine, Settore MED/30, Sickness Impact Profile, Surveys and Questionnaires, medicine, Humans, 030212 general & internal medicine, Intraocular Pressure, Vision, Ocular, Aged, Demography, business.industry, Middle Aged, medicine.disease, eye diseases, glaucoma, quality of life, Ophthalmology, Cross-Sectional Studies, Italy, sociodemographic factor, 030221 ophthalmology & optometry, Quality of Life, Marital status, Disease characteristics, Female, medicine.symptom, business, Glaucoma, Open-Angle
Abstract

Purpose: The purpose of this article was to evaluate the potential association between sociodemographic factors with clinical characteristics, vision-related quality of life (QoL), and glaucoma-related symptoms scores in a large cohort of primary open-angle glaucoma patients. Materials and Methods: Multicenter, cross-sectional study involving academic and nonacademic centers. Previously diagnosed primary open-angle glaucoma patients aged >18 years were enrolled. At baseline, information on demographic characteristics, social, medical and ocular history, clinical presentation and treatments was collected. Vision-related QoL was evaluated by means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), while glaucoma-related symptoms were evaluated using the Glaucoma Symptom Scale (GSS) questionnaire. The associations between sociodemographic factors with clinical characteristics (mean deviation, pattern standard deviation, best-corrected visual acuity), NEI-VFQ-25, and GSS scores were evaluated by means of univariate and multivariate general linear models. Results: A total of 3227 patients were enrolled. Older age and male sex were significantly associated with lower mean deviation (P

Published
2018

4. Referral for first glaucoma surgery in Europe, the ReF-GS study

Author

Hollo, Gabor, Schmidl, Doreen, Hommer, Anton, Stalmans, I., Daphne, T., Fichtl, M., Ruzickova, E., Rezkova, L., Bron, A. M., Hoffmann, E. M., Klezlova, A., Erb, C., Zimmermann, N., Kothy, P., Gandolfi, A., Varano, L., Ungaro, N., Januleviciene, Kuzmiene, L., Beckers, H. J. M., Grabska-Liberek, Majszyk-Ionescu, J., Skowyra, A., Plichta, A., Popa-Cherecheanu, Alina, Chiselita, Dorin, Brezhnev, A., Baranov, A., Babic, N., Miljkovic, A., Ferkova, S. L., Cvenkel, B., Garcia-Feijoo, Julian, Sanchez Jean, Ruben, Taube, Botling A., Irkec, M., Kocabeyoglu, S., Vass, C., MUMC+: MA UECM AIOS (9), MUMC+: MA UECM Oogartsen MUMC (9), RS: MHeNs - R3 - Neuroscience, Oogheelkunde, Semmelweis University, Medizinische Universität Wien = Medical University of Vienna, Hera Hospital, Hôpital Universitaire Leuven, Charles University [Prague] (CU), General University Hospital in Prague, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Mainz University Medical Center, Eye Clinic [Berlin], Partenaires INRAE, University of Parma = Università degli studi di Parma [Parme, Italie], Lithuanian University of Health Science (LUSH), Maastricht University Medical Centre (MUMC), Maastricht University [Maastricht], Medical University, Warsaw, University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), University of Medical Sciences, Kursk State Medical University, University of Novi Sad, Comenius University in Bratislava, University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Karolinska Institutet [Stockholm], Hacettepe University, Department of Nutrition and Dietetics, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Centre National de la Recherche Scientifique (CNRS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), and Université Bourgogne Franche-Comté [COMUE] (UBFC)

Subjects
Male, medicine.medical_specialty, genetic structures, Referral, medicine.medical_treatment, Adrenergic beta-Antagonists, PROGRESSION, Trabeculectomy, Blindness, Exfoliation Syndrome, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Glaucoma surgery, medicine, media_common.cataloged_instance, Humans, European Union, [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs, European union, Carbonic Anhydrase Inhibitors, Referral and Consultation, Intraocular Pressure, media_common, Aged, therapy, business.industry, General surgery, Glaucoma, General Medicine, Middle Aged, medicine.disease, eye diseases, Europe, Ophthalmology, glaucoma surgery, 030221 ophthalmology & optometry, Disease Progression, Timolol, referral, Female, Laser Therapy, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, 030217 neurology & neurosurgery, Glaucoma, Open-Angle
Abstract

Purpose: To analyze the appropriateness of referrals for incisional glaucoma-surgery in Europe. Methods: Referrals for the first open-angle glaucoma surgery between January and October 2017 were analyzed in 18 countries: 8 “old” European Union, 7 “new” European Union and 3 non-European Union European countries. Results: Most eyes had primary open-angle or exfoliative glaucoma. The average mean deviation was −13.8 dB with split fixation in 44.3%. No structural progression analysis was made before the referrals. The most common medications were the combination of a prostaglandin analog, timolol and a carbonic anhydrase inhibitor (30.0%), and all other combinations comprising ⩾ 3 molecules (33.8%). Laser trabeculoplasty was reported in only 18.4%. Of the 294 referrals, 41.5% were appropriate and timely, 35.0% appropriate but later than optimal, and 17.6% appropriate but too late (minimal vision maintained). The treatment period was significantly longer (median: 7 years) in the “old” European Union countries than in the other groups (3 and 2 years, respectively). No between-group differences were seen in intraocular pressure and mean deviation, but the non-European Union group referred the patients at significantly lower cup/disk ratio and eye drop usage than the other groups. Split fixation was significantly more common in the “old” (60.6%) than the “new” European Union countries (38.7%), and in both EU country-groups than in the non-European Union countries (13.6%). Conclusions: Of 294 European open-angle glaucoma referrals for first glaucoma-surgery, 41.5% were completely satisfactory. The damage was typically advanced, and the care varied considerably among the countries. This suggests that further efforts are necessary to improve glaucoma care in Europe.

Published
2018

5. Effects of different membranes and dialysis technologies on patient treatment tolerance and nutritional parameters

Author

Locatelli, F, Mastrangelo, F, Redaelli, B, Ronco, C, Marcelli, D, Lagreca, G, Orlandini, G, Corti, M, Pontoriero, G, Difilippo, S, Rossi, R, Farma, R, Colantonio, P, Martinelli, D, Vasile, A, Allegra, V, Mengozzi, G, Martinbianco, L, Bonomini, V, Stefoni, C, Coli, L, Cianciolo, G, Desanctis, L, Deblasi, V, Alfonso, L, Rizzelli, S, Patruno, P, Brendolan, A, Crepaldi, C, Casu, Md, Mureddu, S, Maiorca, R, Cristinelli, L, Setti, G, Camerini, C, Salvadori, M, Bandini, S, Rosati, A, Mancini, G, Panzetta, G, Ianche, M, Delmastro, G, Cogoni, G, Accalai, Gp, Sechi, Ma, Alloatti, S, Paternoster, G, Gaiter, A, Manes, M, Schena, Fp, Pertosa, G, Bottalico, D, Cantafio, S, Salvo, E, Dagostino, F, Guido, A, Limido, D, Beretta, P, Vigano, Mr, Dadone, G, Verzetti, G, Navino, C, Barbe, Mc, Ruva, Ce, Amato, M, Aterini, S, Ippolito, E, Splendiani, G, Sturniolo, A, Costanzi, S, Passalacqua, S, Scatizzi, A, Dimaggio, A, Montemurro, N, Vercellone, A, Segoloni, G, Pacitti, A, Maffei, S, Scaccia, F, Fini, R, Bandiani, G, Antiga, G, Nicolini, Ma, Asproni, E, Cadinu, F, Salvietti, N, Urti, D, Lorusso, P, Dani, L, Peona, C, Filiberti, O, Porcu, Mc, Barbieri, C, Costa, S, Nicrosini, F, Mioli, V, Bibiano, L, Carletti, P, Panichi, N, Melappioni, M, Mecca, G, Mingardi, G, Perticucci, E, Huber, W, Riegler, P, Giacon, B, Altieri, P, Ferrara, R, Bolasco, Pg, Cabiddu, G, Paolillo, A, Morgante, F, Cascone, C, Deluca, M, Demin, Am, Capotorto, M, Ungaro, N, Specchio, A, Albertazzi, A, Delrosso, G, Bonomini, M, Surian, M, Bonforte, G, Dozio, B, Frizzi, V, Ciciani, Am, Ravaglia, F, Giachino, F, Bosticardo, Gm, Francisco, M, Biasioli, S, Petrosino, L, Chimienti, S, Cristofano, C, Perrone, F, Grassi, C, Orazi, E, Bisegna, S, Bracchi, O, Bazzato, G, Toffoletto, Pp, Tesio, F, Faimondi, A, Boggi, R, Campogiani, V, Gentili, F, Bolasco, F, Pistis, R, Pillosu, I, Stallone, C, Aucella, F, Procaccini, D, Avanzi, C, Sorba, G, Solinas, R, Cossu, M, Deangelis, S, Ripani, R, Piccoli, G, Martina, G, Quarello, F, Borghi, M, Massazza, M, Tagliaferri, M, Pascucci, M, Galiotta, P, Bertolucci, E, Sessa, A, Conte, F, Serbelloni, P, Virgilio, M, Delvino, A, Conte, M, Mura, C, Conti, P, Pinna, A, Neumair, F, Bonadonna, A, Stanic, L, Munaretto, G, Ciccarelli, P, Stefoni, A, Biagini, M, Gerace, Ms, Capece, R, Bordoni, E, Petroselli, F, Scaffone, V, Lombardo, V, Coppola, E, Micucci, G, Concetti, M, Capponi, E, Lisi, E, Raccosta, G, Sanna, Gm, Calvisi, L, Cherchi, Gl, Vitali, P, Castelli, P, Estivi, R, Saporiti, E, Dececco, G, Lorenzi, S, Maschio, G, Tessitore, N, Loschiavo, C, Rovati, C, Andreotti, C, Gilli, P, Depaoli, E, Natili, G, and Pensalfini, V

Subjects
medicine.medical_specialty, Beta-2 microglobulin, business.industry, medicine.medical_treatment, Synthetic membrane, Urology, Ultrafiltration, Liter, Surgery, chemistry.chemical_compound, Membrane, chemistry, Nephrology, medicine, Polysulfone, Hemodialysis, business, Dialysis
Abstract

Effects of different membranes and dialysis technologies on patient treatment tolerance and nutritional parameters. There is increasing evidence that the biochemical and cellular phenomena induced by blood/membrane/dialysate interactions contribute to dialysis-related intradialytic and long-term complications. However, there is a lack of large, prospective, randomized trials comparing biocompatible and bioincompatible membranes, and convective and diffusive treatment modalities. The primary aim of this prospective, randomized trial was to evaluate whether the use of polysulfone membrane with bicarbonate dialysate offers any advantages (in terms of treatment tolerance, nutritional parameters and pre-treatment β 2 -microglobulin levels) over a traditional membrane (Cuprophan®). A secondary aim was to assess whether the use of more sophisticated methods consisting of a biocompatible synthetic membrane with different hydraulic permeability at different ultrafiltration rate (highflux hemodialysis and hemodiafiltration) offers any further advantages. Seventy-one Centers were involved and stratified according to the availability of only the first two or all four of the following techniques: Cuprophan® hemodialysis (Cu-HD), low-flux polysulfone hemodialysis (LfPS-HD), high-flux polysulfone high-flux hemodialysis (HfPS-HD), and high-flux polysulfone hemodiafiltration (HfPS-HDF). The 380 eligible patients were randomized to one of the two or four treatments (132 to Cu-HD, 147 to LfPS-HD, 51 to HfPS-HD and 50 to HfPS-HDF). The follow-up was 24 months. No statistical difference was observed in the algebraic sum of the end points between bicarbonate dialysis with Cuprophan® or with low-flux polysulfone, or among the four dialysis methods under evaluation. There was a significant decrease in pre-dialysis plasma β 2 -microglobulin levels in high-flux dialysis of 9.04 ± 10.46 mg/liter (23%) and in hemodiafiltration of 6.35 ± 12.28 mg/liter (16%), both using high-flux polysulfone membrane in comparison with Cuprophan® and low-flux polysulfone membranes (P = 0.032). The significant decrease in pre-dialysis plasma β 2 -microglobulin levels could have a clinical impact when one considers that β 2 -microglobulin accumulation and amyloidosis are important long-term dialysis-related complications.

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6. Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study

Author

Davide Poli, Eliana Rulli, Luigi Varano, S. Talarico, S. Lateri, Luca Agnifili, C. Gizzi, F. Parravano, Teresa Rolle, E. Maggiolo, P. Vallon, Ilaria Motolese, Andreas Katsanos, S. Marchi, E. Bonacci, O. Vattovani, Luciano Quaranta, V. Pucci, L. Fontana, Francesco Oddone, Lorenza Landi, Luciana Carmassi, Ivano Riva, D. Jannetta, F. Cantatore, A. Bagnis, Carlo Enrico Traverso, Ciro Costagliola, O. Oneta, L. Bossolesi, Ignazio Alberto Zucca, Emilio C. Campos, Giulio Mirabella Roberti, Luca Rossetti, N. Ungaro, V. Tagliavini, A. Cucca, Michele Uva, D. Tognetto, Carlo Sborgia, Roberto Ratiglia, Stefano A. Gandolfi, Giuseppe Giannaccare, Maurizio Fossarello, R. Piccini, Lital Hollander, Gianluca Manni, M. Cassamali, F. Iannacone, R. Scotto, Robert N. Weinreb, M. Musolino, A. Rossi, L. Mastropasqua, T. Carchedi, Valter Torri, Simone Alex Bagaglia, F. Galli, G. Cardarella, Gemma Caterina Maria Rossi, Rulli, E., Quaranta, L., Riva, I., Poli, D., Hollander, L., Galli, F., Katsanos, A., Oddone, F., Torri, V., Weinreb, R. N., Varano, L., Carchedi, T., Talarico, S., Parravano, F., Motolese, I., Bagaglia, S. A., Rossi, G. C. M., Lateri, S., Bossolesi, L., Carmassi, L., Rolle, T., Piccini, R., Ratiglia, R., Rossi, A., Gandolfi, S., Tagliavini, V., Ungaro, N., Fossarello, M., Cucca, A., Zucca, I., Uva, M., Bonacci, E., Cardarella, G., Tognetto, D., Vattovani, O., Vallon, P., Iannacone, F., Fontana, L., Marchi, S., Manni, G. L., Jannetta, D., Roberti, G., Rossetti, L., Maggiolo, E., Oneta, O., Sborgia, C., Cantatore, F., Mastropasqua, L., Agnifili, L., Campos, E., Gizzi, C., Giannaccare, G., Pucci, V., Cassamali, M., Costagliola, C., Traverso, C., Scotto, R., Musolino, M., Landi, L., Bagnis, A., Rulli, Eliana, Quaranta, Luciano, Riva, Ivano, Poli, Davide, Hollander, Lital, Galli, Fabio, Katsanos, Andrea, Oddone, Francesco, Torri, Valter, Weinreb, Robert N., Fontana, Luigi, Marchi, Susanna, Bagaglia, S.A., Rossi, G.C.M., and Manni, G.L.

Subjects
Male, Aging, Visual acuity, genetic structures, lcsh:Medicine, Glaucoma, Neurodegenerative, Eye, 0302 clinical medicine, Quality of life, Visual Field Test, Surveys and Questionnaires, 80 and over, Surveys and Questionnaire, Young adult, lcsh:Science, Aged, 80 and over, Multidisciplinary, Middle Aged, Visual field, Open-Angle, Italy, Female, Visual field loss, medicine.symptom, Glaucoma, Open-Angle, Human, Adult, medicine.medical_specialty, glaucoma, quality of life, Visual field, Open angle glaucoma, Vision Disorders, Italian Study Group on QoL in Glaucoma, and over, Article, 03 medical and health sciences, Young Adult, Clinical Research, Ophthalmology, Settore MED/30, medicine, Humans, Author Correction, Eye Disease and Disorders of Vision, Aged, business.industry, lcsh:R, Vision Disorder, Neurosciences, medicine.disease, eye diseases, Quality of Life, Visual Field Tests, Clinical trial, glaucoma, quality of life, 030221 ophthalmology & optometry, lcsh:Q, business, 030217 neurology & neurosurgery
Abstract

The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients. POAG patients with or without VF defects or “glaucoma suspect” patients were considered eligible. QoL was assessed using the validated versions of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and glaucoma-related symptoms were assessed using the Glaucoma Symptom Scale (GSS). Patients were classified as having VF damage in one eye (VFD-1), both eyes (VFD-2), or neither eye (VFD-0). 3227 patients were enrolled and 2940 were eligible for the analysis. 13.4% of patients were classified in the VFD-0, 23.7% in the VFD-1, and 62.9% in the VFD-2 group. GSS visual symptoms domain (Func-4) and GSS non-visual symptoms domain (Symp-6) scores were similar for the VFD-0 and VFD-1 groups (p = 0.133 and p = 0.834 for Func-4 and Symp-6, respectively). VFD-0 group had higher scores than VFD-2 both in Func-4 (p

Published
2018

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