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Introduction Although several models to predict intensive care unit (ICU) mortality are available, their performance decreases in certain subpopulations because specific factors are not included. Moreover, these models often involve complex techniques and are not applicable in low-resource settings. We developed a prediction model and simplified risk score to predict 14-day mortality in ICU patients infected with Klebsiella pneumoniae. Methodology A retrospective cohort study was conducted using data of ICU patients infected with Klebsiella pneumoniae at the largest tertiary hospital in Northern Vietnam during 2016–2018. Logistic regression was used to develop our prediction model. Model performance was assessed by calibration (area under the receiver operating characteristic curve-AUC) and discrimination (Hosmer-Lemeshow goodness-of-fit test). A simplified risk score was also constructed. Results Two hundred forty-nine patients were included, with an overall 14-day mortality of 28.9%. The final prediction model comprised six predictors: age, referral route, SOFA score, central venous catheter, intracerebral haemorrhage surgery and absence of adjunctive therapy. The model showed high predictive accuracy (AUC = 0.83; p-value Hosmer-Lemeshow test = 0.92). The risk score has a range of 0–12 corresponding to mortality risk 0–100%, which produced similar predictive performance as the original model. Conclusions The developed prediction model and risk score provide an objective quantitative estimation of individual 14-day mortality in ICU patients infected with Klebsiella pneumoniae. The tool is highly applicable in practice to help facilitate patient stratification and management, evaluation of further interventions and allocation of resources and care, especially in low-resource settings where electronic systems to support complex models are missing.

Direct Z-scheme g-C3N4/V2O5 photocatalysts were prepared through a sonication-assisted calcination method. The obtained samples were characterised by X-ray diffraction (XRD),Ultraviolet-visible diffuse reflectance spectroscopy (UV-Vis-DRS), Scanning electron microscope (SEM), andPhotoluminescence spectroscopy (PL). Oxidations of tetracycline hydrochloride (TC) were employed to evaluate the photocatalytic activities of the obtained g-C3N4/V2O5materials. Different weight ratios (5, 10, 15, and 20%) of g-C3N4/V2O5 loaded composites were prepared, in which a 15% (CV-15) loaded composite was found to show optimal catalytic performance for the reaction. The degradation conversation of TC has achieved approximately 79.67% in CV-15 after a 2-hour reaction. g-C3N4/V2O5 photocatalystwas more active than the individual g-C3N4 and V2O5 materials, which could be attributed to the efficient separation of photogenerated electron-hole pairs shown in the photocatalytic mechanism of TC degradation.

Introduction. Ventricular late potentials (VLP) are predictors of cardiac disorders such as sudden death syndrome, myocardial infarction and ventricular tachyarrhythmias. Therefore, VLP assessment allows the severity and possible dangerous consequences of such disorders to be predicted.Aim. To determine errors associated with VLP assessment by high-resolution 12-lead ECG recordings.Materials and methods. VLPs were determined by the modulus of the cardiac electrical vector using signals from orthogonal leads. The conversion error was assessed using synchronous ECG recordings of 12-channel and orthogonal leads, the method of digital filtering (to reduce noise and interference) and the method of identifying characteristic points of the QRS complex and VLPs.Results. The conversion of 12-lead ECG signals into orthogonal signals results in errors associated with the assessment of both the modulus of the cardiac electrical vector and all VLP indicators. The Kors transformation was shown to provide the minimum errors when assessing the cardiac electrical vector modulus in the QRS area, with the errors related to the VRMS assessment not exceeding 0.084 %. The estimation of the QRSd and LAS errors should consider the nature of VLP variations and the zone of uncertainty in their assessment. The ambiguity of the results of assessing the boundaries of violations and the absence of pathologies in cardiac ventricular depolarization indicates the influence of a large number of factors on research accuracy. Errors in the assessment of these factors may result in under- and overestimation of dangerous heart rhythm disturbances and incorrect prediction of the patient' state.Conclusion. The obtained results can be used for reducing errors associated with the assessment of VLP indicators, improving the diagnostic accuracy of dangerous heart rhythm disturbances and predicting disease exacerbation due to structural and morphological disorders of the myocardium.

Zinc oxide (ZnO) is a well-known semiconductor with valuable characteristics: wide direct band gap of ˜3.3 eV, large exciton binding energy of 60 meV at room temperature, high efficient photocatalyst, etc. which have been applied in many fields such as optical devices (LEDs, laser), solar cells and sensors. Besides, various low dimensional structures of ZnO in terms of nanoparticles, nanorods, nanoneedles, nanotetrapods find applications in technology and life. This material is also appealing due to the diversity of available processing methods including both chemical and physical approaches such as: hydrothermal, sol–gel, chemical vapor deposition and sputtering. In this report, ZnO nanorods are prepared by hydrothermal method assisted with galvanic-cell effect. The effect of counter electrode materials on the morphology and structure of obtained product was studied. Scanning electron microscopy (SEM) images of the product showed that counter electrodes made of aluminum offers nanorods of higher quality than other materials in terms of uniform size, high density and good preferred orientation. The as-prepared nanorods were then sputtered with gold (Au). ZnO/Au nanostructures show excellent photocatalyst activities which were demonstrated by complete photodegradation of methylene blue (Mb) under UV irradiation and high decomposition rate k of 0.011 min-1.

In this study, K2SiF6:Mn4+ microcrystals (KSFM) and CsPbBr3 nanocrystals were synthesized step by step via co-precipitation and ligand-assisted re-precipitation, respectively, and applied onto a backlighting unit (BLU) using an irradiated blue light-emitting diode (LED) source. The radiant flux down-conversion efficiency was 50% (blue to green) for a CsPbBr3-embedded poly(methyl methacrylate) plate and 62% (blue to red) for a KSFM-coated chip LED as a phosphor converter. A blue LED/KSFM/CsPbBr3 BLU was successfully applied onto a liquid crystal display. The real backlight display performance exhibited a bright white emission with a CIE chromaticity coordinate of (x = 0.29, y = 0.31) and wide color gamut of 84% of Rec. 2020 standard. Compared with a blue LED/YAG:Ce [color rendering index (CRI) ~ 71], it showed a very low CRI of 37 due to its narrow-band emission. Thus, the BLU could be used in special display applications, which require a high color saturation but not the high CRI of white color displays.

Blood-brain barrier (BBB) dysfunction underlies the pathogenesis of many neurological diseases. Platelet-derived growth factor receptor-alpha (PDGFRα) induces hemorrhagic transformation (HT) downstream of tissue plasminogen activator in thrombolytic therapy of acute stroke. Thus, PDGFs are attractive therapeutic targets for BBB dysfunction. In the present study, we examined the role of PDGF signaling in the process of tissue remodeling after middle cerebral arterial occlusion (MCAO) in mice. Firstly, we found that imatinib increased lesion size after permanent MCAO in wild-type mice. Moreover, imatinib-induced HT only when administrated in the subacute phase of MCAO, but not in the acute phase. Secondly, we generated genetically mutated mice (C-KO mice) that showed decreased expression of perivascular PDGFRα. Additionally, transient MCAO experiments were performed in these mice. We found that the ischemic lesion size was not affected; however, the recruitment of PDGFRα/type I collagen-expressing perivascular cells was significantly downregulated, and HT and IgG leakage was augmented only in the subacute phase of stroke in C-KO mice. In both experiments, we found that the expression of tight junction proteins and PDGFRβ-expressing pericyte coverage was not significantly affected in imatinib-treated mice and in C-KO mice. The specific implication of PDGFRα signaling was suggestive of protective effects against BBB dysfunction during the subacute phase of stroke. Vascular TGF-β1 expression was downregulated in both imatinib-treated and C-KO mice, along with sustained levels of MMP9. Therefore, PDGFRα effects may be mediated by TGF-β1 which exerts potent protective effects in the BBB.

Final-year Pharmacy students are assumed to be at high risk for mental health problems including stress, anxiety and depression, especially during the stage prior to graduation. This study is aimed at investigating the reality of stress, anxiety, and depression suffered by final-year Pharmacy students’ (in the academic year 2019-2020) at two universities in Dongnai via a cross-sectional description based on a Depression, Anxiety and Stress Scale (DASS21) survey questionnaire. The research results from 134 respondents showed that the proportions of students experiencing stress, anxiety, and depression were 16.4%, 29.8% and 38.8% respectively, of which severe anxiety accounted for 6%, and severe depression accounted for 0.7% analysis. There were also statistically significant differences among groups of students with different academic results. These findings contribute to the universities’construction of appropriate intervention strategies to improve students’ mental health with a view to eliminating their mistakes in clinical pharmaceutical practice in the future.

BackgroundLittle is known about the natural history of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.MethodsWe conducted a prospective study at a quarantine center for coronavirus disease 2019 in Ho Chi Minh City, Vietnam. We enrolled quarantined people with reverse-transcription polymerase chain reaction (RT-PCR)–confirmed SARS-CoV-2 infection, collecting clinical data, travel and contact history, and saliva at enrollment and daily nasopharyngeal/throat swabs (NTSs) for RT-PCR testing. We compared the natural history and transmission potential of asymptomatic and symptomatic individuals.ResultsBetween 10 March and 4 April 2020, 14 000 quarantined people were tested for SARS-CoV-2; 49 were positive. Of these, 30 participated in the study: 13 (43%) never had symptoms and 17 (57%) were symptomatic. Seventeen (57%) participants imported cases. Compared with symptomatic individuals, asymptomatic people were less likely to have detectable SARS-CoV-2 in NTS collected at enrollment (8/13 [62%] vs 17/17 [100%]; P = .02). SARS-CoV-2 RNA was detected in 20 of 27 (74%) available saliva samples (7 of 11 [64%] in the asymptomatic group and 13 of 16 [81%] in the symptomatic group; P = .56). Analysis of RT-PCR positivity probability showed that asymptomatic participants had faster viral clearance than symptomatic participants (P ConclusionsAsymptomatic SARS-CoV-2 infection is common and can be detected by analysis of saliva or NTSs. The NTS viral loads fall faster in asymptomatic individuals, but these individuals appear able to transmit the virus to others.

The study investigates the impact of factors on environmental accounting implementation in mining enterprises in Binh Dinh province, Vietnam. The survey was carried out in three phases: 1) a draft survey form; 2) in-depth interviews with experts; 3) design questionnaire. The survey respondents were people who had knowledge of environmental information in mining enterprises in Binh Dinh province, including: accountant, chief accountant, financial deputy director or director. The questionnaire was is sent directly or through Google Form tool. The author received 162 responses votes from the survey respondent, out of which 13 were unusable due to missing data. Thus, 149 valid responses votes were used. This study employs Cronbach’s alpha analysis, exploratory factor analysis and multivariate regression analysis. The results showed the influence of five different factors on environmental accounting implementation in mining enterprises in Binh Dinh province: stakeholders pressure, corporate characteristics, coercive pressure of government agencies, environmental awareness of senior managers and accountant qualifications of environmental accounting. While the pressure of stakeholders has a negligible influence, the remaining four factors (coercive pressure of government agencies, environmental awareness of senior executives, business characteristics, accountant qualifications of environmental ac

Preeclampsia, with the hallmark features of new-onset hypertension and proteinuria after 20 weeks of gestation, is a major cause of fetal and maternal morbidity and mortality. Studies have demonstrated a role for the renin-angiotensin system (RAS) in its pathogenesis; however, small-molecule RAS blockers are contraindicated because of fetal toxicity. We evaluated whether siRNA targeting maternal hepatic angiotensinogen (Agt) could ameliorate symptoms of preeclampsia without adverse placental or fetal effects in 2 rodent models. The first model used a cross of females expressing human Agt with males expressing human renin, resulting in upregulation of the circulating and uteroplacental RAS. The second model induced ischemia/reperfusion injury and subsequent local and systemic inflammation by surgically reducing placental blood flow midgestation (reduced uterine perfusion pressure [RUPP]). These models featured hypertension, proteinuria, and fetal growth restriction, with altered biomarkers. siRNA treatment ameliorated the preeclamptic phenotype in both models, reduced blood pressure, and improved intrauterine growth restriction, with no observed deleterious effects on the fetus. Treatment also improved the angiogenic balance and proteinuria in the transgenic model, and it reduced angiotensin receptor activating antibodies in both. Thus, an RNAi therapeutic targeting Agt ameliorated the clinical sequelae and improved fetal outcomes in 2 rodent models of preeclampsia.

We investigate thin film resistive thermometry based on metal-to-insulator-transition (niobium nitride) materials down to very low temperature. The variation of the NbN thermometer resistance have been calibrated versus temperature and magnetic field. High sensitivity in tempertaure variation detection is demonstrated through efficient temperature coefficient of resistance. The nitrogen content of the niobium nitride thin films can be tuned to adjust the optimal working temperature range. In the present experiment, we show the versatility of the NbN thin film technology through applications in very different low temperature use-cases. We demonstrate that thin film resistive thermometry can be extended to temperatures below 30 mK with low electrical impedance., Comment: Article accepted for publication in JLTP

The environmental information disclosure of enterprises listed on Vietnam’s stock market has been mandated by the Ministry of Finance of Vietnam according to Circular No. 155/2015/TT_BTC. Therefore, enterprises need to be responsible for announcing and interpreting financial and non-financial information about the environment to meet the needs of the Government and stakeholders. However, the level of environmental information disclosure depends on their business, company characteristics, compliance of the board of management, etc. This paper investigates and assesses the level of environmental information disclosure of the listed companies on the stock market in Vietnam. The study was conducted with 170 listed companies on the Hanoi Stock Exchange (HNX) and Ho Chi Minh City Stock Exchange (HOSE) through descriptive statistics and value testing methods and an in-depth interview. The research results have shown that in Vietnam, the level of enterprises announcing environmental information disclosure is still low. For example, materials and construction industry, food and beverage industry have less than 55% of enterprise disclosing environmental information. At the same time, the enterprises from environmentally sensitive sectors such as materials and construction, electricity, petroleum, gas, chemicals, etc., have more environmental information disclosure than other industries, and the environmental information published only focuses on the environmental debt, the amount of resources consumed, the number of environmental violations, environmental policies and objectives, etc.

Complement-mediated damage to the neuromuscular junction (NMJ) is a key mechanism of pathology in myasthenia gravis (MG), and therapeutics inhibiting complement have shown evidence of efficacy in the treatment of MG. In this study, we describe the development of a subcutaneously administered N-acetylgalactosamine (GalNAc)-conjugated small interfering RNA (siRNA) targeting the C5 component of complement that silences C5 expression in the liver (ALN-CC5). Treatment of wild-type rodents with ALN-CC5 resulted in robust and durable suppression of liver C5 expression. Dose-dependent serum C5 suppression was observed in non-human primates, with a lowering of serum C5 of up to 97.5% and the concomitant inhibition of serum complement activity. C5 silencing was efficacious in ameliorating disease symptoms in two standard rat models of MG, demonstrating the key role of circulating C5 in pathology at the NMJ. Improvement in disease activity scores and NMJ pathology was observed at intermediate levels of complement activity inhibition, suggesting that complete ablation of complement activity may not be required for efficacy in MG. The pre-clinical studies of ALN-CC5 and efficacy of C5 silencing in rat models of MG support further clinical development of ALN-CC5 as a potential therapeutic for the treatment of MG and other complement-mediated disorders. Keywords: myasthenia gravis, small-interfering RNA, complement pathway, siRNA therapeutic

According to Shipbuilding Industry Corporation (SBIC), in 2017, shipbuilding value reached more than VND 3,071 billion, equal to 69% of the plan. Other fields have increased significantly, such as: Ship repair reached VND 488.3 billion, equal to 125% of the plan; supporting industry reached VND 264.5 billion, equal to 123% of the plan. Although shipbuilding has not reached the plan, but looking back on the period from 2008 to now, this field is always in a situation of hardship and bottomless decline because of lack of jobs, these are quite satisfactory numbers. The cause of the decline is due to the world shipping and shipbuilding industry has experienced an extremely difficult period due to the heavy influence of the world economic crisis from 2008 up to now. The Vietnamese shipbuilding and shipping industry is also not out of that situation. For the shipbuilding industry to develop, specific policies, with specific support addresses, are needed, which are well-designed and visionary shipbuilding development programs.

Background Over recent decades, Vietnam has experienced rapid economic growth, a nutrition transition from the traditional diet to highly-processed and calorie-dense foods and beverages, and an increasing prevalence of childhood overweight/obesity (ow/ob). The goal of this study is to describe the patterns of ow/ob in a longitudinal sample of Vietnamese children from ages 1 to 8, and the sociodemographic and behavioral factors associated with ow/ob at age 8. Methods This study is a secondary data analysis of a geographically-representative, longitudinal cohort of 1961 Vietnamese children from the Young Lives Cohort Study from 2002 to 2009. Thirty-one communities were selected with oversampling in rural communities, and children age 1 were recruited from each community using simple random sampling. Surveys of families and measurements of children were collected at child ages 1, 5, and 8. Our specified outcome measure was childhood ow/ob at age 8, defined by the World Health Organization’s thresholds for body-mass-index (BMI) for age Z-scores. Associations between early and concurrent socio-behavioral factors, childhood nutrition and physical activity variables were analyzed using STATA 15. Bivariate and multivariable analyses were completed utilizing logistic regression models. Results The prevalence of ow/ob increased from 1.1% in both sexes at age 1 to 7% in females and 13% in males at age 8. Bivariate analyses show greater likelihood of ow/ob at age 8 was significantly associated with early life sociodemographic factors (at age 1), male sex (OR = 2.2, 1.6–3.1), higher wealth (OR = 1.1–1.4), and urban residence (OR = 4.3, 3–6). In adjusted analyses, ow/ob at age 8 was associated with early nutrition practices at age 5, including frequent consumption of powdered milk (OR = 2.8, 1.6–4.6), honey/sugar (OR = 2.7, 1.8–4.1), prepared restaurant/fast foods (OR = 4.6, 2.6–8.2), and packaged sweets (OR = 3.4, 2.3–4.9). In addition, breastfeeding for 6 months or longer was protective against obesity at age 8 (OR = 0.3, 0.1–0.9). Conclusions We found that increased consumption of powdered milk, honey/sugar, packaged sweets, and prepared restaurants/fast foods are associated with childhood ow/ob. In contrast, breastfeeding for 6 months or longer was protective against childhood ow/ob. These findings suggest that public health programs and campaigns aimed to prevent childhood ow/ob in Vietnam should target early feeding practices.

BackgroundOne hundred days after SARS-CoV-2 was first reported in Vietnam on January 23rd, 270 cases have been confirmed, with no deaths. We describe the control measures used by the Government and their relationship with imported and domestically-acquired case numbers, with the aim of identifying the measures associated with successful SARS-CoV-2 control.MethodsClinical and demographic data on the first 270 SARS-CoV-2 infected cases and the timing and nature of Government control measures, including numbers of tests and quarantined individuals, were captured by Vietnam’s National Steering Committee for COVID-19 response. Apple and Google mobility data provided proxies for population movement. Serial intervals were calculated from 33 infector-infectee pairs and used to estimate the proportion of pre-symptomatic transmission events and time-varying reproduction numbers.FindingsAfter the first confirmed case on January 23rd, the Vietnamese Government initiated mass communications measures, case-contact tracing, mandatory 14-day quarantine, school and university closures, and progressive flight restrictions. A national lockdown was implemented between April 1st and 22nd. Around 200 000 people were quarantined and 266 122 RT-PCR tests conducted. Population mobility decreased progressively before lockdown. 60% (163/270) of cases were imported; 43% (89/208) of resolved infections remained asymptomatic for the duration of infection. 21 developed severe disease, with no deaths. The serial interval was 3.24 days, and 27.5% (95% confidence interval, 15.7%-40.0%) of transmissions occurred pre-symptomatically. Limited transmission amounted to a maximum reproduction number of 1.15 (95% confidence interval, 0.37-2.36). No community transmission has been detected since April 15th.InterpretationVietnam has controlled SARS-CoV-2 spread through the early introduction of mass communication, meticulous contact-tracing with strict quarantine, and international travel restrictions. The value of these interventions is supported by the high proportion of asymptomatic and imported cases, and evidence for substantial pre-symptomatic transmission.FundingThe Vietnam Ministry of Health and Wellcome Trust, UK.Research in contextEvidence before this studyVietnam was one of the first countries outside of China to detect imported and human-to-human transmitted SARS-CoV-2 within its borders. Yet, as of May 1st, a total of only 270 cases have been confirmed, no deaths have occurred, and no community transmission has been detected since April 15th despite intensive screening, tracing and testing. We did a PubMed database search to identify studies investigating COVID-19 response in Vietnam using the terms “Vietnam”, “COVID-19”, and “SARS-CoV-2”. All relevant articles were evaluated. Studies describe cases of COVID-19 and their management, aspects of the government response from newspapers and online government sources, but there are no previous reports using national data to describe and investigate the national epidemic and the impact of control measures cases over time.Added value of this studyWe used data from the National Steering Committee for COVID-19 response to give a comprehensive account of the first 100 days of the SARS-CoV-2 epidemic in Vietnam, including case numbers and their symptomatology, the estimated reproductive number by week, and their relation to the multiple control measures instituted by the Vietnam Government over time. We show two distinctive features of Vietnam’s response. First, the Government took rapid actions to restrict international flights, closed schools and universities, and instituted meticulous case-contact tracing and quarantining from late January, well before these measures were advised by WHO. Second, they placed mass communication, education, and the identification, serial testing, and 14-day quarantine of all direct contacts of cases, regardless of symptom development, at the heart of the response. The value of strict contact-tracing and quarantine is supported by the high proportion of asymptomatic cases (43%) and imported cases (60%), and evidence for substantial pre-symptomatic transmission.Implications of all the available evidenceVietnam has had remarkable success in controlling the emergence of SARS-CoV-2. Our report provides a complete picture of the control of SARS-CoV-2 in Vietnam, with lessons for other Governments seeking to extend national SARS-CoV-2 control or prevent future epidemics. Our findings shows the importance of acting early, before the virus becomes established in the community, and before the case numbers overwhelm systems of case-contact tracing and mass quarantine. They also demonstrate the value of effective mass communication in rapidly educating the public in infection prevention measures and providing real-time information on the state of the epidemic.

Background Obesity is a global epidemic and prevalence of obesity is higher in African Americans (AAs) compared to Caucasians. The endocannabinoid system (EC) and polymorphism in the endocannabinoid receptor type 1 (CNR1) gene 3813A/G and 4895A/G and in the fatty acid amide hydrolase (FAAH) are associated with obesity. The objective was to explore racial and sex differences in these polymorphism and the biochemical abnormalities seen in obesity. Methods A cross-sectional study of 667 subjects (53.67% female), 49.18% were AA; 69.72% were obese (body mass index [BMI] ≥30) were screened for CNR1 3813, 4895 and FAAH 385 polymorphisms using a real-time polymerase chain reaction (PCR) system. Results Subjects with FAAH 385 polymorphisms were more likely to be obese (75.14% vs. 67.81, P = 0.046). There were no significant sex differences for CNR1 3813 and CNR1 4895; or between obese and control group. AAs had higher prevalence of CNR1 3813 (OR, 2.80, 95% CI, 1.95–4.04) and FAAH 385 (OR, 2.48, 95% CI, 1.82–3.38). Association between African American race and the three genotypes persisted after adjustment of all the variables (P Conclusion FAAH 385 polymorphism is more likely seen in obese and in older subjects. AAs had higher prevalence of CNR1 3813 and FAAH 385 polymorphism; and lower prevalence of CNR1 4895 polymorphisms. These findings may explain some of the racial differences, but not the sex differences in the clinical expression of obesity.

In this paper, the seven traditional models of photovoltaic (PV) modules are reviewed comprehensively to find out the appropriate model for reliability. All the models are validated using the Matlab code and graphical comparisons between models are made. The accuracy and convergence of each model is evaluated using the data of manufactured PV panels. Then, a novel model is proposed showing its consistent performance. The three most key parameters of the single-diode model are self-revised to adapt to various types of PV modules. This new method is verified in three types of PV panels’ data measured by the National Renewable Energy Laboratory (NREL), USA. The validated data show promising results when the error RMSEs’ range of the proposed model is under 0.36.

Thanks to unique Raman spectra of chemical substances, a growing number of applications in environmental and biomedical fields based on Raman scattering has been developed. However, the low probability of Raman scattering hindered its potential development and thus, many different techniques were developed to enhance Raman signal. A key step of surface-enhanced Raman scattering technique is to prepare active SERS substrate from noble metals. The main enhancement mechanism is electromagnetic enhancement resulted from surface plasmon resonance. The disadvantages of nanoparticles based SERS substrates include high randomness due to self - assembly process of nanoparticles. Recently, a new kind of SERS substrates with order nanostructures of semiconductors combining with noble metals can serve as active SERS substrates, which are expected to possess high enhancement of Raman signals. In this study, ordered ZnO nanorods were first prepared by galvanic hydrothermal method and gold was sputtered on the as prepared ZnO nanomaterials to enhance Raman. Our SERS substrates exhibit promising high enhancement factors, and can detect chemical substances at concentration in nano molar range.

In recent years, the development of world shipbuilding and shipbuilding technology has set new requirements for Vietnam Shipbuilding industry, which must be gradually developed on a par with the region and the world. This requires the domestic shipping industry to quickly apply advanced technologies, shorten construction time. At the same time, the training team of highly qualified technicians and workers can be trained to proficiently use new technological equipment. The study of modern specialized equipment for construction and assembly and centering on repair of the shaft system - the main engine of cargo ships is very important.. This article examines the features, specifications, usage of laser generator- Microgage 2D to effectively apply to the process of centering and assembling main engines and axles on ships. At the same time, research and design suitable jigs for microgage 2D applications in teaching practice at Shipyard engineers.

Slags are a co-product produced by the steel manufacturing industry and have mainly been utilised for aggregates in concreting and road construction. The increased utilisation of slag can increase economic growth and sustainability for future generations by creating a closed-loop system, circular economy within the metallurgical industries. Slags can be used as a soil amendment, and slag characteristics may reduce leachate potential of heavy metals, reduce greenhouse gas emissions, as well as contain essential nutrients required for agricultural use and environmental remediation. This review aims to examine various slag generation processes in steel plants, their physicochemical characteristics in relation to beneficial utilisation as a soil amendment, and environmental implications and risk assessment of their utilisation in agricultural soils. In relation to enhancing recycling of these resources, current and emerging techniques to separate iron and phosphorus slag compositions are also outlined in this review. Although there are no known immediate direct threats posed by slag on human health, the associated risks include potential heavy metal contamination, leachate contamination, and bioaccumulation of heavy metals in plants, thereby reaching the food chain. Further research in this area is required to assess the long-term effects of slag in agricultural soils on animal and human health.

Objective: Evaluate the characters of labrum tear morphology in recurrent anterior dislocation of shoulder via arthroscopy.

This paper proposes an observer-based digital control system to manage active and reactive powers in a Dual-Active-Bridge converter. Since they are proportional to the direct and the quadrature components of the transferred current, Id and Iq, respectively, the power management is realized by regulating the two current components. An observer is designed to estimate them from the feedback voltage and the average absolute value of the transferred current. Since all the feedback signals for the observer are DC quantities, the sampling speed is not necessary to be very high. A digital controller is then synthesized to regulate Id and Iq at desired values. In the control system, the bridge shift angle is used to handle Iq, meanwhile the switching frequency is variable to manipulate Id. The current command for Id is calculated from the desired active power, meanwhile, by assigning a positive value for Iq control loop, soft turn on is easily achieved. The performance of the observer as well as the digital control system is validated by a laboratory-scale experiment system.

This paper focuses on autonomous multi-islanded entities and the seamless reconnection to the main grid as the self-healing ability of the future power system. The minimization of power quality issues (mainly that of voltage, frequency, and harmonics) in such entities based on controllers, with or without intercommunication, is also an important part of this paper. The future power system, with the significant penetration of distributed generations (DGs), can rapidly respond to any problem occurring within it by separating into autonomous islanded entities to prevent the disconnection of DGs. As a result, high-quality and continuous power is supplied to consumers. Finally, future research that is necessary for the realization of the future power system is discussed.

BACKGROUND: Pityriasis lichenoides et varioliformis acuta (PLEVA) is an uncommon condition which presents acutely with papulo-vesicles that may develop necrotic, ulcerative, or hemorrhagic changes. AIM: We studied clinical, and treatment characteristics of PLEVA hospitalised patients at our hospital from September 2009 to December 2014. METHODS: The records of 15 PLEVA patients were retrospectively reviewed. RESULTS: The median age of onset was 21.8 ± 18.81 (from 1 to 68), male to female ratio was 2/1. The common area of onset was trunk (60.0%) and extremities (33.3%). Clinical features were purpuric papules (100%), hemorrhagic crusted papules (46.7%), pustular purpuric papules (40%), and necrotic ulcerating lesions (13.3%). CONCLUSION: All patients were received systemic antibiotics (macrolides: 53.3%, others: 46.7%), 2 patients were added immunosuppressive drugs. A 1-year-old patient died, others had a good response.

The interlinking converters is one of the important components in the hybrid mirogrid system, the study of structure and control method of the interlinking converters in hybrid mirogrid has been implemented and achieved positive results. This paper proposes an improved decentralized control of level-shifted carrier-based PWM for a modular multilevel interlinking converter (IC-MMC) in standalone hybrid microgrid (HMG-Hybrid Microgrid). Main research objectives is to study the capability of the decentralized control method proposed for the IC-MMC unit when performing the power exchange control task between the DC and AC bus in the HMG system, increased flexibility in controls. Furthermore, the proposed control method for IC-MMC for HMG is also verified in term of dynamically reconfiguration when changing the number of modules in the MMC when the improve of system reliability is needed. The feasibility of the carrier level shift control method for IC-MMC in HMG has been verified by simulation model on MATLAB/Simulink software to evaluate the ability to exchange power between the DC bus and the AC bus.

Introduction to education is one of the basic courses in teacher education professional education, it covers a wide range of subjects. Thus, in order to practice the management teaching goals, the interdisciplinary developed mathematical tools are applied for the study. The participants of this study are students in course of introduction to education, and the research instruments applied are rough set, grey structural modeling (GSM), and matrix based-structural modeling (MSM). The purposes of this paper are: 1) To logically analyze educational datasets to practice the scientific traits in education; 2) To benefit from directed hierarchical analysis to identify and propose action planning; 3) To construct core-oriented educational structure as the criterion-reference for one-lesson-multiple-design and to provide the whole scope and visualized analysis with GSM and MSM.

Objectives: 1) Study the clinical and radiographic characteristics of both bones forearm fractures in adults. 2) Evaluate the surgical outcomes of plate and screws fi xation for these fractures.

Rationale Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solitary well-circumscribed lung parenchymal lesion, and is often located in juxtapleural or juxtafissural positions. On histopathology, it consists of cuboidal surface cells and stromal round cells, both of which are positive for thyroid transcription factor-1. Here we report a case of a young PSP male patient and review the relevant literature in order to improve our understanding of this disease. Patient concerns An 18-year-old man was referred to our hospital after accidentally finding a lesion on chest X-ray. Contrast-enhanced computed tomography showed a soft tissue mass with homogeneous enhancement in the left lower lobe posterior segment. Diagnoses The diagnosis of PSPs was confirmed by histopathological examination. Interventions and outcomes The patient underwent a thoracoscopic wedge resection and was followed-up after that. One month later, he had good performance status with no recurrent tumors. Lessons PSP in a young man is really uncommon, and is confused with malignant tumors. A histopathological examination is considered as the diagnostic gold standard for this uncommon tumor. Surgery is the main treatment.

Objectives Wait times for autism spectrum disorder (ASD) evaluations are long, thereby delaying access to ASD-specific services. We asked how our traditional care model (requiring all patients to see psychologists for ASD diagnostic decisions) compared to an alternative model that better utilizes the available clinicians, including initial evaluation by speech, audiology, and pediatrics (trained in Level 2 autism screening tools). Pediatricians could diagnose immediately if certain about diagnosis but could refer uncertain cases to psychology. Accuracy and time to diagnosis, charges, and parent satisfaction were our main outcome measures. Methods Data were gathered through record extraction (n = 244) and parent questionnaire (n = 57). We compared time to diagnosis, charges, and parent satisfaction between traditional and alternative models. Agreement between pediatrician and psychologist diagnoses was examined for a subset (n = 18). Results The alternative model's time to diagnosis was 44% faster (85 vs 152 d) and 33% less costly overall. Diagnostic agreement was 93% for children with ASD diagnoses and 100% for children without ASD diagnoses. Pediatricians expressed higher diagnostic certainty about children with higher levels of ASD symptoms. Parents reported no differences in high satisfaction with experiences, family-centered care, and shared decision making. Conclusion Efficient use of available clinicians with additional training in Level 2 autism screening resulted in improvements in time to diagnosis and reduced charges for families. Coordination of multidisciplinary teams makes this possible, with strategic sequencing of patients through workflow. Flexibility was key to not only allowing pediatricians to refer uncertain cases to psychology for diagnosis but also allowing for diagnosis by a pediatrician when symptomatic presentation clearly met diagnostic criteria.

In this paper, we report our work on building linguistic resources for Vietnamese social network text analysis in multiple domains. We first describe our annotation methodology including guidelines development, annotation softwares and quality assurance. We then present results of the first pilot phase of the project. Finally, we outline some perspectives of our ongoing corpus development and their expected results.

In this paper, we present a large phase range unit-cell for X-band passive transmitarray antennas. The unit-cell is designed by using the combination of cut-circular patches and cut-ring slots. A 3-bit phase resolution has been optimized to provide eight values of the transmission phase with a step of 45°. The bandwidth of −1 dB transmission magnitude reaches 21.3%. A 10x10-element transmitarray based on the unit-cell configuration has been simulated. The transmitarray antenna provides good radiation patterns and a high aperture efficiency of 52.1%.

Automatic Test Equipment (ATE) obsolescence drives a requirement for rehosting Test Program Sets (TPSs). However, due to the many variations of programming languages, in most cases, the target language of the new ATE platform differs from the legacy language. This paper discusses a flexible, modular software approach for TPS rehost efforts. The new approach can be used to convert code while also allowing for the automated creation of additional output products (e.g., Test Requirements Document (TRD), Automatic Test Markup Language (ATML) files, fault universe, and ATE instrument requirements). Furthermore, the modular design and nonspecific, intermediate data structure significantly improves code reusability for rehosting between different ATE platforms. Additionally, as a case study, this paper discusses the benefits achieved using this approach.

ECG signal processing and analysis for the on-line atrial fibrillation detection by remote monitoring systems of patient's heart rhythm under physical activity condition. In order to improve atrial fibrillation episodes diagnostics reliability methods and algorithms of alternant premature contractions and atrial flutter detection, reduction of electromyographic noise and artifacts of locomotor activity are developed. Algorithm of atrial fibrillation detection based on complexification of diagnostically significant parameters is suggested.

The emergence of Distributed Generation (DG) in the electric system has brought about the appearance of the islanding phenomenon. In AC networks, there are a lot of Islanding Detection Methods (IDMs) have been studied. However, not too much IDMs in DC networks have been published because of the absence of frequency and reactive power. The hybrid IDM based on injected perturbation signal and rate of change of power output is proposed. This IDM can detect islanding condition not only in the worst case (the power of load and PV are equal) but also in another case (the power of load is greater than the power of PV). It can be applicable to both single and multi-PV operation scenarios. Besides, the effectiveness of the proposed method is verified by simulation in Matlab/Simulink.

During the past decade, cardiothoracic surgery (CTS) education has undergone tremendous change with the advent of new technologies and the implementation of integrated programs, to name a few. The goal of this study was to assess how residents' career paths, training, and perceptions changed during this period.The 2006 to 2014 surveys accompanying the Thoracic Surgery Residents Association/Thoracic Surgery Directors' Association in-training examination taken by CTS residents were analyzed, along with a 2003 survey of graduating CTS residents. Of 2,563 residents surveyed, 2,434 (95%) responded.During the decade, fewer residents were interested in mixed adult cardiac/thoracic practice (20% in 2014 vs 52% in 2003, p = 0.004), more planned on additional training (10% in 2003 vs 41% to 47% from 2011 to 2014), and the frequent use of simulation increased from 1% in 2009 to 24% in 2012 (p0.001). More residents recommended CTS to potential trainees (79% in 2014 vs 65% in 2010, p = 0.007). Job offers increased from a low of 12% in 2008 with three or more offers to 34% in 2014. Debt increased from 0% with more than $200,000 in 2003 to 40% in 2013 (p0.001). Compared with residents in traditional programs, more integrated residents in 2014 were interested in adult cardiac surgery (53% vs 31%) and congenital surgery (22% vs 7%), fewer were interested in general thoracic surgery (5% vs 31%, p0.001), and more planned on additional training (66% vs 36%, p0.001).With the evolution in CTS over the last decade, residents' training and career paths have changed substantially, with increased specialization and simulation accompanied by increased resident satisfaction and an improved job market.

This letter proposes a novel method to reject $6n \pm 1$ harmonics in the stator voltage at the point of common coupling (PCC) for a stand-alone doubly-fed induction generator (DFIG) supplying a balanced three-phase diode rectifier. These harmonics are rejected by using the rotor current controller in the fundamental synchronous reference frame. The proposed control algorithm is based on a proportional integral controller and a bank of resonant filters. In this frame, each resonant filter in the rotor current controller has the possibility of rejecting one pair of the positive and the negative stator harmonic voltages at the PCC. Experimental results with 2.2-kW DFIG are shown in this letter.

Grey Structural Modeling (GSM) is an effective tool for analyzing complex systems and has been used in many educational researches in recent years. This study developed a tool to determine the relational structure between items and relational structure between students according to the GSM method. GSM-RGSM software, which is the result of this study, was developed by the MATLAB language. The software processes the data which is the result of a text and then provides results in graphs. GSM-RGSM software will help the user to reduce the complex mathematical calculations when using GSM method and provide results accurately and quickly. A graphical user interface is also designed to help users quickly become familiar and easy to use software. This software also provides RGSM graph, which is considered as a special case of the GSM. In this paper, a practical example of using GSM-RGSM software to analyze math test results is used as illustration for the application of the software in educational

The purpose of this study is to predict the academic achievement of student based on the combination of GM(1,1) and Taylor approximation method(abbreviated as T-GM(1,1)). The prediction model combined the first-order two variables grey differential equation model from grey system theory and Taylor approximation method from approximation optimization theory. This combined model can obtain the most optimal predicted value by multi-times approximate calculation. In addition, the researchers used MATLAB software to build a MATLAB toolbox for the prediction model based on GM(1,1) and T-GM(1,1). The experimental results showed that T-GM(1,1) can be adjusted repeatedly until reaches the optimal values and makes the predicted error reduce to the minimum. The comparison of the obtained results with the original GM(1,1) showed that T-GM(1,1) is a good alternative for parameters optimization of this prediction model.

In this paper, a new four-facet drill was presented and analyzed. For evaluating the performance of the new and conventional drills, the geometrical analyses of the rake faces and flank surfaces as well as the prediction of cutting forces and torques were conducted. The results showed that the normal rake and clearance angles along the cutting lips of the new drill are always positive and a positive constant, respectively. In contrast, those of the conventional one are negative at certain points on cutting lips close to the drill axis and variable, respectively. Therefore, the cutting forces and torques of the new drill in drilling can be reduced as compared with the conventional one. The prediction of cutting forces and torques in drilling the workpiece made of plain-carbon steel (AISI1045) showed that the reductions of the total thrust force and torque along cutting lips for the new drill over the conventional drill are up to 50.12 and 26.54 %, respectively, and hence, the tool life of the new drill is expected to be longer than the conventional one’s.

The main purpose of this research is to develop a toolbox for GSP chart and Rasch GSP methods. Through GSP chart analysis, teachers get information to diagnose the learning status of students and the quality of items. Rasch GSP provides information to assess the quality of the classes and test quality. The RGSP Toolbox 1.0 developed by this study is not a toolbox that implements calculation according to the basic steps of the two above methods. In order to increase the application range of the toolbox, this study has also proposed and executed a number of improvements. So, the RGSP Toolbox 1.0 is a useful tool to support teachers and researchers in educational achievement. This toolbox can quickly calculate and give exact results, draw graphs clearly. In addition, a graphical user interface (GUI) is also designed to be easy for use. The toolbox not only supplies researchers with big support in their research process but also can provide feedbacks about teaching and learning for teachers and students. So students can make reasonable adjustments for learning activity and teachers have an effective reference for guidance of learning.

Background Inappropriate antimicrobial use (AMU) is strongly associated with antimicrobial resistance. The Global Point Prevalence Survey (Global-PPS) is a standardized tool that is used worldwide to characterize inpatient AMU. We report pediatric results from 26 Canadian hospitals that participated in the Global-PPS in 2018. Methods The survey was completed by each site on the Global-PPS website for all patients aged 0–17 years hospitalized in a neonatal or pediatric ward on a chosen day between January and December 2018. Data collected included ward type, demographics, antimicrobials prescribed, diagnosis, type of indication (community-acquired [CA] vs. healthcare-associated [HA]) and type of therapy (empiric vs. targeted). Quality indicators included guideline compliance, medical record documentation of diagnosis, antimicrobial stop/review date, and surgical prophylaxis (SP) duration. Results Of the 26 sites, 23 were mixed and 3 were pediatric hospitals, with data on 767 inpatients. Overall, 25.8% (n = 198) of patients received at least one antimicrobial, and 21.9% (n = 168) were on at least one antibiotic. The highest AMU was found in Hematology-Oncology (84%), Pediatric Intensive Care (55.3%) and surgical (42.1%) units. Of the 330 antimicrobial prescriptions, 40.9% were for CA infections, 23% for medical prophylaxis, 20% for HA infections and 2.7% for SP. The most commonly treated infections were sepsis (16%) and lower respiratory tract infection (12.1%). The top five prescribed antibiotics were aminopenicillins (20.4%), aminoglycosides (16.1%), third-generation cephalosporins (15.4%), piperacillin–tazobactam (7.5%) and trimethoprim-sulfamethoxazole (7.5%). Diagnosis and stop/review date were documented for 88.1% and 65.1% of prescriptions, respectively. Compliance to local guidelines was found in 91.5% of therapies. SP exceeded 24 hours in 88.9% of courses. Conclusion The Global-PPS generated Canada-wide data on inpatient pediatric AMU, which will allow hospitals to benchmark and develop local quality improvement interventions to enhance appropriate AMU. Targets for improvement include suboptimal antimicrobial stop/review date documentation and prolonged SP. Disclosures All authors: No reported disclosures.

Cu2ZnSnS4 (CZTS) is a p-type semiconductor with kesterite/stannite structure. CZTS has band gap of about 1.0–1.5 eV, and a high absorption coefficient (over 104 cm−1), which is ideal for making absorber layer in solar cells. CZTS is only composed of abundant earth and environment friendly elements so this material can contribute to the sustainable development of photovoltaic field and to reducing the cost of solar cells. Hydrothermal method, with many advantages such as simplicity, cost saving, was used to produce CZTS material in this research. Raman scattering, X-ray diffraction, transmission electron microscopy, and energy dispersive X-ray spectroscopy show that the products are nanocrystals of kesterite phase with uniform size distribution. The chemical pathway for the formation of kesterite phase was also discussed based on Raman results.