Author: "Tim, R." / Topic: business.industry - Searchworks@Jio Institute Digital Library Search Results

815 results on '"Tim, R."'

1. Prevascularized Retrievable Hybrid Implant to Enhance Function of Subcutaneous Encapsulated Islets

Author: Paul D. Dalton, Vijayaganapathy Vaithilingam, Bernard E. Tuch, Luke Carroll, Auvro R. Mridha, Michael B. Morris, Tim R. Dargaville, CBITE, and RS: MERLN - Cell Biology - Inspired Tissue Engineering (CBITE)
Subjects: Blood Glucose, medicine.medical_specialty, melt electrowriting, type 1 diabetes, Biomedical Engineering, Urology, Islets of Langerhans Transplantation, Bioengineering, Capsules, Mice, SCID, Biochemistry, SCAFFOLDS, MICROCAPSULES, Diabetes Mellitus, Experimental, Biomaterials, Cell therapy, foreign body reaction, Islets of Langerhans, Mice, BETA-CELLS, vascularization, DESIGN, Mice, Inbred NOD, medicine, TRANSPLANTED ISLETS, Animals, Humans, Insulin, geography, Type 1 diabetes, geography.geographical_feature_category, business.industry, islet transplantation, Treatment options, SITE, POLYMER, Islet, medicine.disease, EFFICACY, Diabetes Mellitus, Type 1, microencapsulation, Implant, cell therapy, business, Function (biology)
Abstract: Replacement of pancreatic beta-cells is one of the most promising treatment options for treatment of type 1 diabetes (T1D), even though, toxic immunosuppressive drugs are required. In this study, we aim to deliver allogeneic beta-cell therapies without antirejection drugs using a bioengineered hybrid device that contains microencapsulated beta-cells inside 3D polycaprolactone (PCL) scaffolds printed using melt electrospin writing (MEW). Mouse beta-cell (MIN6) pseudoislets and QS mouse islets are encapsulated in alginate microcapsules, without affecting viability and insulin secretion. Microencapsulated MIN6 cells are then seeded within 3D MEW scaffolds, and these hybrid devices implanted subcutaneously in streptozotocin-treated diabetic NOD/SCID and BALB/c mice. Similar to NOD/SCID mice, blood glucose levels (BGL) are lowered from 30.1 to 4.8 mM in 25-41 days in BALB/c. In contrast, microencapsulated islets placed in prevascularized MEW scaffold 3 weeks after implantation in BALB/c mice normalize BGL (Impact statementThe retrievable 3D printed PCL scaffold we have produced promotes vascularization when implanted subcutaneously and allows seeded microencapsulated insulin-producing cells to normalize blood glucose of diabetic mice for at least 2 months, without the need for antirejection drugs to be administered. The scaffold is scalable for possible human use, but will require modification to ensure that normalization of blood glucose levels can be maintained long term.
Published: 2022

2. Pharmacokinetics and Safety of the Abacavir/Lamivudine/Lopinavir/Ritonavir Fixed-Dose Granule Formulation (4-in-1) in Neonates: PETITE Study

Author: Adrie Bekker, Isabelle Andrieux-Meyer, Mukesh Kumar, Helena Rabie, Marisa Groenewald, Petite Study Team, James Nielsen, Edmund V. Capparelli, Tim R. Cressey, Nicolas Salvadori, Marc Lallemant, Samantha du Toit, Ratchada Cressey, Kanchana Than-in-at, and Mark F. Cotton
Subjects: medicine.medical_specialty, Nevirapine, Anti-HIV Agents, Lopinavir/ritonavir, HIV Infections, Gastroenterology, Lopinavir, Zidovudine, immune system diseases, Abacavir, Internal medicine, medicine, Humans, Pharmacology (medical), Ritonavir, business.industry, Infant, Newborn, virus diseases, Lamivudine, Abacavir/Lamivudine, Dideoxynucleosides, Infectious Diseases, Drug Therapy, Combination, business, medicine.drug
Abstract: Antiretroviral options for neonates (younger than 28 days) should be expanded. We evaluated the pharmacokinetics, safety, and acceptability of the "4-in-1" fixed-dose pediatric granule formulation of abacavir/lamivudine/lopinavir/ritonavir (30/15/40/10 mg) in neonates.The PETITE study is an ongoing phase I/II, open-label, single-arm, 2-stage trial conducted in South Africa. In stage 1, term neonates exposed to HIV on standard antiretroviral prophylaxis (nevirapine ± zidovudine) received single dose(s) of the 4-in-1 formulation, followed by intensive pharmacokinetic sampling and safety assessments. At each PK visit, blood was drawn after an observed dose at 1, 2, 4, 8, and 12 hours postdose. In this study, we have reported the planned interim pharmacokinetic and safety analysis after completion of the single-dose administration.Sixteen neonates, with a median (range) birth weight of 3130 g (2790-3590 g), completed 24 pharmacokinetic visits. The 4-in-1 formulation imposed relatively high doses of abacavir [8.6 mg/kg (6.6-11.4)] and lamivudine [4.3 mg/kg (3.3-5.7)] but lower doses of lopinavir [11.5 mg/kg (8.8-15.2)]. The geometric means (GM, 90% CI) AUC0-12 of abacavir, lamivudine, and lopinavir were 29.87 (26.29-33.93), 12.61 (10.72-14.83), and 3.49 (2.13-5.72) µg.h/mL, respectively. Lopinavir GM AUC0-12 was below the predefined target (20-100 µg.h/mL), and ritonavir concentrations were only detectable in 4 of the 120 (3%) samples. No adverse events were related to study drugs. No neonate had difficulty swallowing the 4-in-1 formulation.The high doses of abacavir and lamivudine (in mg/kg) and AUCs were safe, and the formulation was well tolerated; however, lopinavir/ritonavir exposures were extremely low, preventing its use in neonates use in neonates. Alternative pediatric solid antiretroviral formulations must be studied in neonates.
Published: 2021

3. Serum Theophylline Concentrations in very Preterm Neonates Receiving Intravenous Aminophylline for Apnea

Author: Weerawadee Chandranipapongse, Pimol Wongsiridej, Tim R. Cressey, Siripa Usaha, and Sopapan Ngerncham
Subjects: Very preterm, business.industry, Anesthesia, medicine, Apnea, Theophylline, Aminophylline, General Medicine, medicine.symptom, business, medicine.drug
Abstract: Objective: To determine the percentage of neonates who achieved therapeutic theophylline level (TTL) after receiving standard IV loading/maintenance aminophylline doses. To assess factors associated with achieving therapeutic theophylline concentrations and to describe adverse effects of aminophylline. Materials and Methods: This was a pilot, cross-sectional study. Preterm neonates ≤34 weeks’ gestation for which aminophylline was indicated for treatment of apnea were enrolled. Standard IV aminophylline dosage is 8 mg/ kg loading dose, followed by 1.5 mg/kg maintenance dose every 8 hours. Serum theophylline concentrations were measured prior to the 8th maintenance dose. Descriptive statistics, univariate and multivariate analyses were performed. Results: Twenty-five neonates (52% female) were enrolled: mean (standard deviation) gestational age and birth weight were 30.4 (2) weeks and 1,277 (415) grams, respectively. Aminophylline was initiated at a median (25%tile, 75%tile) postnatal age of 4 (1, 8) days. Baseline heart rate prior to the loading dose was 153 (13) beats-per-minute. Sixty percent of neonates achieved a therapeutic theophylline level. In the univariate analysis, being male and postnatal age ≤5 days were associated with successfully achieving a TTL. After adjusting for gender, postnatal age ≤5 days was the only factor associated with achieving a TTL (adjusted odds ratio 17.7, 95% confidence interval: 1.9, 164.4). Tachycardia and feeding intolerance were observed in 44% and 24% of neonates, respectively. Conclusion: Current IV aminophylline dosing conditions in Thailand achieved TTL in approximately two-thirds of neonates, suggesting therapeutic drug monitoring is beneficial for guiding dosing. A higher maintenance dose could be considered for neonates older than 5 days.
Published: 2021

4. University of Alabama at Birmingham Nathan Shock Center: comparative energetics of aging

Author: Liou Y. Sun, Tim R. Nagy, Andrew W. Brown, John L. Hartman, Christy S. Carter, Thomas W. Buford, Victor M. Darley-Usmar, Scott W. Ballinger, David B. Allison, Daniel L. Smith, Jianhua Zhang, and Steven N. Austad
Subjects: Aging, Geriatrics gerontology, business.industry, Energetics, Review, Comparative biology, Biology, Multiple species, Mitochondria, Rats, Analytics, Evolutionary biology, Animals, Geriatrics and Gerontology, business, Signal Transduction
Abstract: The UAB Nathan Shock Center focuses on comparative energetics and aging. Energetics, as defined for this purpose, encompasses the causes, mechanisms, and consequences of the acquisition, storage, and use of metabolizable energy. Comparative energetics is the study of metabolic processes at multiple scales and across multiple species as it relates to health and aging. The link between energetics and aging is increasingly understood in terms of dysregulated mitochondrial function, altered metabolic signaling, and aberrant nutrient responsiveness with increasing age. The center offers world-class expertise in comprehensive, integrated energetic assessment and analysis from the level of the organelle to the organism and across species from the size of worms to rats as well as state-of-the-art data analytics. The range of services offered by our three research cores, (1) The Organismal Energetics Core, (2) Mitometabolism Core, and (3) Data Analytics Core, is described herein.
Published: 2021

5. Healthcare professional preferences in the health and fitness assessment and optimization of older patients facing colorectal cancer surgery

Author: Karen Kerr, Matthew Lee, Maria Burton, Lynda Wyld, Tim R. Wilson, Susan Moug, Sarah Daniels, and Steven R Brown
Subjects: Response rate (survey), medicine.medical_specialty, Descriptive statistics, Attitude of Health Personnel, business.industry, Health Personnel, Prehabilitation, Gastroenterology, Computer-assisted web interviewing, medicine.disease, Colorectal surgery, Older patients, Surveys and Questionnaires, Colorectal cancer surgery, Family medicine, medicine, Humans, Dementia, Colorectal Neoplasms, business, Digestive System Surgical Procedures, Aged
Abstract: Aim: There are few age‐ and fitness‐specific, evidence‐based guidelines for colorectal cancer surgery. The uptake of different assessment and optimization strategies is variable. The aim of this study was to explore healthcare professional opinion about these issues using a mixed methods design. Methods: Semi‐structured qualitative interviews were undertaken with healthcare professionals from a single UK region involved in the treatment, assessment and optimization of colorectal surgery patients. Interviews were analysed using the framework approach. An online questionnaire survey was subsequently designed and disseminated to UK surgeons to quantitatively assess the importance of interview themes. Descriptive statistics were used to analyse questionnaire data. Results: Thirty‐seven healthcare professionals out of 42 approached (response rate 88%) were interviewed across five hospitals in the south Yorkshire region. Three broad themes were developed: attitudes towards treatment of the older patient, methods of assessment of suitability and optimization strategies. The questionnaire was completed by 103 out of an estimated 256 surgeons (estimated response rate 40.2%). There was a difference in opinion regarding the role of major surgery in older patients, particularly when there is coexisting dementia. Assessment was not standardized. Access to optimization strategies was limited, particularly in the emergency setting. Conclusion: There is wide variation in the process of assessment and provision of optimization strategies in UK practice. Lack of evidence‐based guidelines, cost and time constraints restrict the development of services and pathways. Differences in opinion between surgeons towards patients with frailty or dementia may account for some of the variation in colorectal cancer outcomes.
Published: 2021

6. Efficacy and safety of ravidasvir plus sofosbuvir in patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis (STORM-C-1): interim analysis of a two-stage, open-label, multicentre, single arm, phase 2/3 trial

Author: Sasikala Siva, Anchalee Avihingsanon, Nicole Ngo-Giang-Huong, Hoi-Poh Tee, Suparat Khemnark, Alistair Swanson, Isabelle Andrieux-Meyer, François Simon, Haniza Omar, Kanawee Thetket, Shahnaz Murad, Sombat Thanprasertsuk, Sabine Yerly, Caroline Menetrey, Vishal Goyal, Bernard Pécoul, Satawat Thongsawat, Muhammad Radzi Abu Hassan, Francois Bompart, Wah-Kheong Chan, Suresh Kumar, Soek-Siam Tan, Tim R. Cressey, Nicolas Salvadori, and Hajjah Rosaida Hj Mohd Said
Subjects: Adult, Liver Cirrhosis, Male, medicine.medical_specialty, Cirrhosis, Genotype, Sustained Virologic Response, Sofosbuvir, Hepatitis C virus, HIV Infections, Hepacivirus, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Clinical endpoint, medicine, Humans, Adverse effect, Aged, Hepatology, Coinfection, business.industry, Malaysia, Gastroenterology, Valine, Hepatitis C, Chronic, Middle Aged, Thailand, medicine.disease, Interim analysis, Clinical trial, Treatment Outcome, Upper respiratory tract infection, 030220 oncology & carcinogenesis, RNA, Viral, Benzimidazoles, Drug Therapy, Combination, Female, 030211 gastroenterology & hepatology, Safety, business, medicine.drug
Abstract: In low-income and middle-income countries, affordable direct-acting antivirals are urgently needed to treat hepatitis C virus (HCV) infection. The combination of ravidasvir, a pangenotypic non-structural protein 5A (NS5A) inhibitor, and sofosbuvir has shown efficacy and safety in patients with chronic HCV genotype 4 infection. STORM-C-1 trial aimed to assess the efficacy and safety of ravidasvir plus sofosbuvir in a diverse population of adults chronically infected with HCV.STORM-C-1 is a two-stage, open-label, phase 2/3 single-arm clinical trial in six public academic and non-academic centres in Malaysia and four public academic and non-academic centres in Thailand. Patients with HCV with compensated cirrhosis (Metavir F4 and Child-Turcotte-Pugh class A) or without cirrhosis (Metavir F0-3) aged 18-69 years were eligible to participate, regardless of HCV genotype, HIV infection status, previous interferon-based HCV treatment, or source of HCV infection. Once daily ravidasvir (200 mg) and sofosbuvir (400 mg) were prescribed for 12 weeks for patients without cirrhosis and for 24 weeks for those with cirrhosis. The primary endpoint was sustained virological response at 12 weeks after treatment (SVR12; defined as HCV RNA12 IU/mL in Thailand and HCV RNA15 IU/mL in Malaysia at 12 weeks after the end of treatment). This trial is registered with ClinicalTrials.gov, number NCT02961426, and the National Medical Research Register of Malaysia, NMRR-16-747-29183.Between Sept 14, 2016, and June 5, 2017, 301 patients were enrolled in stage one of STORM-C-1. 98 (33%) patients had genotype 1a infection, 27 (9%) had genotype 1b infection, two (1%) had genotype 2 infection, 158 (52%) had genotype 3 infection, and 16 (5%) had genotype 6 infection. 81 (27%) patients had compensated cirrhosis, 90 (30%) had HIV co-infection, and 99 (33%) had received previous interferon-based treatment. The most common treatment-emergent adverse events were pyrexia (35 [12%]), cough (26 [9%]), upper respiratory tract infection (23 [8%]), and headache (20 [7%]). There were no deaths or treatment discontinuations due to serious adverse events related to study drugs. Of the 300 patients included in the full analysis set, 291 (97%; 95% CI 94-99) had SVR12. Of note, SVR12 was reported in 78 (96%) of 81 patients with cirrhosis and 153 (97%) of 158 patients with genotype 3 infection, including 51 (96%) of 53 patients with cirrhosis. There was no difference in SVR12 rates by HIV co-infection or previous interferon treatment.In this first stage, ravidasvir plus sofosbuvir was effective and well tolerated in this diverse adult population of patients with chronic HCV infection. Ravidasvir plus sofosbuvir has the potential to provide an additional affordable, simple, and efficacious public health tool for large-scale implementation to eliminate HCV as a cause of morbidity and mortality.National Science and Technology Development Agency, Thailand; Department of Disease Control, Ministry of Public Health, Thailand; Ministry of Health, Malaysia; UK Aid; Médecins Sans Frontières (MSF); MSF Transformational Investment Capacity; FIND; Pharmaniaga; Starr International Foundation; Foundation for Art, Research, Partnership and Education; and the Swiss Agency for Development and Cooperation.
Published: 2021

7. Postoperatives Dumping-Syndrom mit nachhaltiger Störung der Glukosehomöostase – Linderung durch Flash-Glukosemessung und individuelle Indikationsstellung für Glucagon-like-Peptide-1(GLP-1)-Rezeptoragonisten

Author: Volker Schmitz, Laura Brecht, Marcus Dahlem, Clemens Ballmann, Tim R. Glowka, Jule Leuz, and Jacob Nattermann
Subjects: Side effect, Gastric emptying, business.industry, Gastroenterology, Blood sugar, Octreotide, Hypoglycemia, Bioinformatics, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Blood Glucose Self-Monitoring, Medicine, Glucose homeostasis, 030211 gastroenterology & hepatology, Dumping syndrome, 030212 general & internal medicine, business, medicine.drug
Abstract: ZusammenfassungDas Auftreten von Dumping-Syndromen nach Magenresektion/Magenteilresektion ist keine Seltenheit. Die Beschwerden sind vielfältig mit vasomotorischen Reaktionen mit Kollapsneigung und Verdauungsstörungen (Frühdumping) und Blutzuckerentgleisungen aufgrund zu schneller Aufnahme von Glukose im Dünndarm (Spätdumping).Etablierte Therapieansätze führen nicht immer zu den gewünschten Therapieerfolgen. Wie auch im hier vorliegenden Fallbeispiel werden dann individuelle Therapiekonzepte nötig, um die Lebensqualität der Patienten wiederherzustellen.
Published: 2021

8. Antiseptic mouthwash for gonorrhoea prevention (OMEGA): a randomised, double-blind, parallel-group, multicentre trial

Author: Matthew Law, David J Templeton, Vincent J Cornelisse, David A. Lewis, Catriona S. Bradshaw, Eric P F Chow, Marcus Y Chen, Rebecca Guy, Richard D. Moore, Lei Zhang, David M. Whiley, Basil Donovan, Jennifer Danielewski, Andrew E. Grulich, Anna McNulty, John M. Kaldor, Tim R H Read, Gerald L. Murray, Kate Maddaford, Deborah A Williamson, Jane S Hocking, Benjamin P Howden, Rebecca Wigan, and Christopher K Fairley
Subjects: Adult, Male, medicine.medical_specialty, Gonorrhea, Population, Mouthwashes, Men who have sex with men, law.invention, Glucose Oxidase, Sexual and Gender Minorities, Young Adult, Double-Blind Method, Randomized controlled trial, law, Surveys and Questionnaires, Internal medicine, medicine, Humans, Multicenter Studies as Topic, Cumulative incidence, Lactoperoxidase, Homosexuality, Male, education, Respiratory Tract Infections, education.field_of_study, Terpenes, business.industry, Incidence (epidemiology), Australia, medicine.disease, Neisseria gonorrhoeae, Salicylates, Clinical trial, Drug Combinations, Infectious Diseases, Clinical research, Anti-Infective Agents, Local, Muramidase, business, New Zealand
Abstract: Summary Background To address the increasing incidence of gonorrhoea and antimicrobial resistance, we compared the efficacy of Listerine and Biotene mouthwashes for preventing gonorrhoea among men who have sex with men (MSM). Methods The OMEGA trial was a multicentre, parallel-group, double-blind randomised controlled trial among MSM, done at three urban sexual health clinics and one general practice clinic in Australia. Men were eligible if they were diagnosed with oropharyngeal gonorrhoea by nucleic acid amplification test (NAAT) in the previous 30 days or were aged 16–24 years. They were randomly assigned to receive Listerine (intervention) or Biotene (control) via a computer-generated sequence (1:1 ratio, block size of four). Participants, clinicians, data collectors, data analysts, and outcome adjudicators were masked to the interventions after assignment. Participants were instructed to rinse and gargle with 20 mL of mouthwash for 60 s at least once daily for 12 weeks. Oropharyngeal swabs were collected by research nurses every 6 weeks, and participants provided saliva samples every 3 weeks, to be tested for Neisseria gonorrhoeae with NAAT and quantitative PCR. The primary outcome was proportion of MSM diagnosed with oropharyngeal N gonorrhoeae infection at any point over the 12-week period, defined as a positive result for either oropharyngeal swabs or saliva samples by NAAT, and the cumulative incidence of oropharyngeal gonorrhoea at the week 12 visit. A modified intention-to-treat analysis for the primary outcome was done that included men who provided at least one follow-up specimen over the 12-week study period. The trial was registered on the Australian and New Zealand Clinical Trials Registry (ACTRN12616000247471). Findings Between March 30, 2016, and Oct 26, 2018, 786 MSM were screened and 256 were excluded. 264 MSM were randomly assigned to the Biotene group and 266 to the Listerine group. The analysis population included 227 (86%) men in the Biotene group and 219 (82%) in the Listerine group. Oropharyngeal gonorrhoea was detected in ten (4%) of 227 of MSM in the Biotene group and in 15 (7%) of 219 in the Listerine group (adjusted risk difference 2·5%, 95% CI −1·8 to 6·8). The cumulative incidence of oropharyngeal gonorrhoea at the week 12 visit did not differ between the two mouthwash groups (adjusted risk difference 3·1%, 95% CI −1·4 to 7·7). Interpretation Listerine did not reduce the incidence of oropharyngeal gonorrhoea compared with Biotene. However, previous research suggests that mouthwash might reduce the infectivity of oropharyngeal gonorrhoea; therefore, further studies of mouthwash examining its inhibitory effect on N gonorrhoeae are warranted to determine if it has a potential role for the prevention of transmission. Funding Australian National Health and Medical Research Council.
Published: 2021

9. Estimating surface solar irradiance from geostationary Himawari-8 over Australia: A physics-based method with calibration

Author: Andrew D. L. Steven, Maryam Mahsal Khan, Jing Huang, Tim R. McVicar, Yi Qin, and Sam West
Subjects: Renewable Energy, Sustainability and the Environment, business.industry, 020209 energy, 02 engineering and technology, Albedo, 021001 nanoscience & nanotechnology, Solar energy, Solar irradiance, Ancillary data, Atmospheric radiative transfer codes, 0202 electrical engineering, electronic engineering, information engineering, Calibration, Geostationary orbit, General Materials Science, 0210 nano-technology, business, Water vapor, Remote sensing
Abstract: Surface Solar Irradiance (SSI) is required for solar energy planning and adoption, and is a fundamental parameter in modelling weather, climate, ecosystem and agricultural activities. Herein a time series based radiative transfer model was developed to simultaneously retrieve properties of clouds, aerosols and surface albedo, which were in turn used to calculate the components of SSI: i.e., global, direct and diffuse irradiance. The calculated results were calibrated across the Australian continent against in-situ measurements to account for minor factors (e.g., water vapor) not considered by the physics-based method. Detailed validation of the SSI components was performed against three years of in-situ measurements at 11 sites across Australia, at a range of time scales (i.e., instantaneous, hourly, daily and monthly) and under both all-sky and cloudy-sky conditions. The main advantage of the present method is the reliable separation of the direct and diffuse components with consistently low biases (~4 W/m2) at all four time scales, while still maintaining relatively low RMSE (root-mean-square-error) and MAE (mean-absolute-error). Once calibration has been performed the model does not require any ancillary data when implemented operationally: that is the model only requires geostationary satellite data. This model may be implemented across the globe using widely available next generation geostationary satellite data with a handful of ground-data for calibration.
Published: 2021

10. Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir

Author: Jeremiah D. Momper, John N. van den Anker, André Dallmann, Mark Mirochnick, Dionna J Green, Brookie M. Best, Xiaomei I Liu, Tim R. Cressey, Gilbert J. Burckart, and Natella Rakhmanina
Subjects: Adult, 0301 basic medicine, Drug, Glucuronosyltransferase, Pyridones, Placenta, media_common.quotation_subject, 030106 microbiology, Pharmacology, Emtricitabine, Models, Biological, 030226 pharmacology & pharmacy, Piperazines, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacotherapy, Pharmacokinetics, Pregnancy, Raltegravir Potassium, Oxazines, medicine, Humans, Pharmacology (medical), media_common, Fetus, biology, business.industry, Infant, Newborn, Raltegravir, chemistry, Dolutegravir, biology.protein, Female, business, Heterocyclic Compounds, 3-Ring, medicine.drug
Abstract: Little is understood about neonatal pharmacokinetics immediately after delivery and during the first days of life following intrauterine exposure to maternal medications. Our objective was to develop and evaluate a novel, physiologically based pharmacokinetic modeling workflow for predicting perinatal and postnatal disposition of commonly used antiretroviral drugs administered prenatally to pregnant women living with human immunodeficiency virus. Using previously published, maternal-fetal, physiologically based pharmacokinetic models for emtricitabine, dolutegravir, and raltegravir built with PK-Sim/MoBi®, placental drug transfer was predicted in late pregnancy. The total drug amount in fetal compartments at term delivery was estimated and subsequently integrated as initial conditions in different tissues of a whole-body, neonatal, physiologically based pharmacokinetic model to predict drug concentrations in the neonatal elimination phase after birth. Neonatal elimination processes were parameterized according to published data. Model performance was assessed by clinical data. Neonatal physiologically based pharmacokinetic models generally captured the initial plasma concentrations after delivery but underestimated concentrations in the terminal phase. The mean percentage error for predicted plasma concentrations was − 71.5%, − 33.8%, and 76.7% for emtricitabine, dolutegravir, and raltegravir, respectively. A sensitivity analysis suggested that the activity of organic cation transporter 2 and uridine diphosphate glucuronosyltransferase 1A1 during the first postnatal days in term newborns is ~11% and ~30% of that in adults, respectively. These findings demonstrate the general feasibility of applying physiologically based pharmacokinetic models to predict washout concentrations of transplacentally acquired drugs in newborns. These models can increase the understanding of pharmacokinetics during the first postnatal days and allow the prediction of drug exposure in this vulnerable population.
Published: 2021

11. Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement

Author: Adrie Bekker, Angela Colbers, Kimberly A Struble, Lactating Women, Yodit Belew, Edmund V. Capparelli, Jennifer J. Kiser, Mark Mirochnick, Elaine J. Abrams, Jeremiah D. Momper, Ahizechukwu C. Eke, Tim R. Cressey, Brookie M. Best, Martina Penazzato, Graham P. Taylor, Catriona Waitt, and Adeniyi Olagunju
Subjects: PHARMACOKINETICS, Infectious Disease Transmission, Breastfeeding, HIV Infections, Reproductive health and childbirth, Pharmacology, 030226 pharmacology & pharmacy, participants of the WHO-IMPAACT workshop on “Approaches to Optimize and Accelerate Pharmacokinetic Studies in Pregnant and Lactating Women”, 0302 clinical medicine, MILK, Pregnancy, Infant Mortality, Vertical, Pharmacology (medical), Pharmacology & Pharmacy, Pregnancy Complications, Infectious, Drug Approval, Pediatric, Clinical Trials as Topic, Infectious, Pharmacology and Pharmaceutical Sciences, Breast Feeding, 030220 oncology & carcinogenesis, 6.1 Pharmaceuticals, HIV/AIDS, Female, 1115 Pharmacology and Pharmaceutical Sciences, Life Sciences & Biomedicine, Algorithms, Pediatric Research Initiative, Anti-HIV Agents, Clinical Trials and Supportive Activities, MEDLINE, SPOTS, VALIDATION, Article, 03 medical and health sciences, EFAVIRENZ, DRIED BLOOD, Acquired immunodeficiency syndrome (AIDS), Clinical Research, medicine, Humans, Lactation, Dosing, EXPOSURE, Developing Countries, Science & Technology, business.industry, Prevention, Patient Selection, Infant, Newborn, Infant exposure, Evaluation of treatments and therapeutic interventions, Infant, Study design, CLINICAL-APPLICATION, QUANTIFICATION, Perinatal Period - Conditions Originating in Perinatal Period, medicine.disease, Newborn, Infectious Disease Transmission, Vertical, Antiretroviral, Clinical trial, Pregnancy Complications, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Good Health and Well Being, Pharmacodynamics, EMTRICITABINE, business
Abstract: Contains fulltext : 235789.pdf (Publisher’s version ) (Open Access) Information on the extent of drug exposure to mothers and infants during pregnancy and lactation normally becomes available years after regulatory approval of a drug. Clinicians face knowledge gaps on drug selection and dosing in pregnancy and infant exposure during breastfeeding. Physiological changes during pregnancy often result in lower drug exposures of antiretrovirals, and in some cases a risk of reduced virologic efficacy. The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) network and the World Health Organization (WHO)-convened Pediatric Antiretrovirals Working Group collaboratively organized a workshop of key stakeholders in June 2019 to define key standards to generate pharmacology data for antiretrovirals to be used among pregnant and lactating women; review the antiretroviral product pipeline; describe key gaps for use in low-income and middle-income countries; and identify opportunities to undertake optimal studies allowing for rapid implementation in the clinical field. We discussed ethical and regulatory principles, systemic approaches to obtaining data for pregnancy pharmacokinetic/pharmacodynamic (PK/PD) studies, control groups, optimal sampling times during pregnancy, and pharmacokinetic parameters to be considered as primary end points in pregnancy PK/PD studies. For lactation studies, the type of milk to collect, ascertainment of maternal adherence, and optimal PK methods to estimate exposure were discussed. Participants strongly recommended completion of preclinical reproductive toxicology studies prior to phase III, to allow study protocols to include pregnant women or to allow women who become pregnant after enrolment to continue in the trial. The meeting concluded by developing an algorithm for design and interpretation of results and noted that recruitment of pregnant and lactating women into clinical trials is critical.
Published: 2021

12. Drug–drug interaction between itraconazole capsule and efavirenz in adults with HIV for talaromycosis treatment

Author: Ariya Chindamporn, Saowaluck Yasri, Thira Sirisanthana, Romanee Chaiwarith, Tim R. Cressey, Navaporn Worasilchai, and Quanhathai Kaewpoowat
Subjects: Adult, Cyclopropanes, Male, Microbiology (medical), medicine.medical_specialty, Antifungal Agents, Efavirenz, Adolescent, Itraconazole, Drug-drug interaction, Human immunodeficiency virus (HIV), HIV Infections, medicine.disease_cause, Gastroenterology, Young Adult, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, medicine, Humans, Drug Interactions, Pharmacology (medical), Active metabolite, Pharmacology, business.industry, Capsule, Middle Aged, Benzoxazines, Infectious Diseases, Mycoses, Pharmaceutical Preparations, chemistry, Alkynes, Concomitant, Female, business, medicine.drug
Abstract: ObjectivesTo assess the pharmacokinetic of itraconazole capsule formulation and its active metabolite, hydroxyitraconazole, in adults with HIV diagnosed with talaromycosis in an endemic area, and to evaluate the drug–drug interaction between itraconazole/hydroxyitraconazole (ITC/OH-ITC) and efavirenz.MethodsOpen-label, single arm, sequential pharmacokinetic study. Eligible subjects were adults with HIV, ≥18 years old, with confirmed talaromycosis, initiating itraconazole capsule as part of standard talaromycosis treatment, in whom efavirenz-based ART was anticipated. Steady-state pharmacokinetic assessments (pre-dose and at 1, 3, 4, 5, 6, 8 and 12 h post dose) were performed for itraconazole/hydroxyitraconazole without and with efavirenz use. Mid-dose efavirenz concentrations were also assessed. Pharmacokinetics parameters were calculated using non-compartmental analysis.ResultsTen subjects (70% male) were enrolled. At entry, median (range) age was 29.5 years (22–64), and CD4 cell count was 18.0 (1–39) cells/mm3. Geometric mean (95% CI) of itraconazole and hydroxyitraconazole AUC0–12 without efavirenz were 9097 (6761–12 239) and 11 705 (8586-15 959) ng·h/mL, respectively, with a median metabolic ratio of OH-ITC : ITC of 1.3 (95% CI 0.9–1.9). Intra-subject comparison revealed that both itraconazole and hydroxyitraconazole exposures were significantly reduced with concomitant efavirenz use, with the mean AUC0–12 of itraconazole and hydroxyitraconazole being 86% (71%–94%) and 84% (64%–97%) lower, respectively. With efavirenz, itraconazole trough concentrations were also below the recommended therapeutic level (0.5 μg/mL). All subjects had mid-dose efavirenz concentrations >1000 ng/mL.ConclusionsConcomitant administration of itraconazole capsule with efavirenz significantly reduced itraconazole and hydroxyitraconazole exposures. The clinical impact of this drug–drug interaction on talaromycosis treatment or prophylaxis in the era of potent ART needs further evaluation.
Published: 2020

13. Interventionelle und chirurgische Therapie der portalen Hypertension

Author: Jörg C. Kalff, Tim R. Glowka, and Steffen Manekeller
Subjects: business.industry, Medicine, General Medicine, business
Published: 2020

14. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

Author: Dmitri Nepogodiev, Joana Ff Simoes, Elizabeth Li, Maria Picciochi, James C Glasbey, Glauco Baiocchi, Ruth Blanco-Colino, Daoud Chaudhry, Ehab AlAmeer, Kariem El-Boghdadly, Funmilola Wuraola, Dhruva Ghosh, Rohan R Gujjuri, Ewen M Harrison, Herman Lule, Haytham Kaafarani, Mohammad Khosravi, Irmgard Kronberger, Sezai Leventoğlu, Harvinder Mann, Kenneth A Mclean, Mengistu Gebreyohanes Mengesha, Maria Marta Modolo, Faustin Ntirenganya, Lisa Norman, Oumaima Outani, Riinu Pius, Peter Pockney, Ahmad Uzair Qureshi, April Camilla Roslani, Sohei Satoi, Catherine Shaw, Aneel Bhangu, Omar M Omar, Waheed-Ul-Rahman Ahmed, Leah Argus, Alasdair Ball, Edward P Bywater, Amanpreet Brar, Brett E Dawson, Irani Duran, Muhammed Elhadi, Conor S Jones, Sivesh K Kamarajah, James M Keatley, Samuel Lawday, Ella J Marson, Riinu Ots, Irène Santos, Elliott H Taylor, Isobel M Trout, Chris Varghese, Mary L Venn, William Xu, Irida Dajti, Arben Gjata, Salah Eddine Oussama Kacimi, Luis Boccalatte, Daniel Cox, Philip Townend, Felix Aigner, Irmgard Elisabeth Kronberger, Elgun Samadov, Amer Alderazi, Kamral Hossain, Greg Padmore, Gabrielle van Ramshorst, Ismaïl Lawani, Anis Cerovac, Samir Delibegovic, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Muhammad Gohar, Mihail Slavchev, Chukwuemeka Nwegbu, Arnav Agarwal, Janet Martin, Joshua Ng-Kamstra, Maricarmen Olivos, Wenhui Lou, Dong-Lin Ren, Jose Andres Calvache, Carlos J Perez Rivera, Ana Danic Hadzibegovic, Tomislav Kopjar, Jakov Mihanovic, Pablo Mijahil Avilés Jiménez, Nikolaos Gouvas, Jaroslav Klat, René Novysedlák, Nicolas Amisi, Peter Christensen, Alaa El-Hussuna, Sylvia Batista, Eddy Lincango-Naranjo, Sameh Emile, Danilo Alfonso Arévalo Sandoval, Hailu Dhufera, Samuel Hailu, Mengistu G Mengesha, Joonas H Kauppila, Alexis P Arnaud, Zaza Demetrashvili, Markus Albertsmeier, Hans Lederhuber, Markus W Löffler, Daniel Kwesi Acquah, Bernard Ofori, Stephen Tabiri, Symeon Metallidis, Georgios Tsoulfas, Maria-Lorena Aguilera-Arevalo, Gustavo Recinos, Tamás Mersich, Dániel Wettstein, Gabriele Kembuan, Peiman Brouki Milan, Mohammad Hossein Khosravi, Masoud Mozafari, Ahmed Hilmi, Helen Mohan, Oded Zmora, Gaetano Gallo, Francesco Pata, Gianluca Pellino, Yuki Fujimoto, Naoto Kuroda, Mohamad K Abou Chaar, Faris Ayasra, Ildar Fakhradiyev, Intisar Hisham Said Hamdun, Jang Jin-Young, Mohammad Jamal, Lina Karout, Aiste Gulla, Fanjandrainy Rasoaherinomenjanahary, Luc Hervé Samison, Iran Irani Durán Sánchez, Diana Samantha Gonzalez, Laura Martinez, María José Martínez, Alejandra Nayen, Antonio Ramos-De la Medina, Jade Nunez, Pueya Rashid Nashidengo, Rakesh Shah, Ashish Lal Shrestha, Pascal Jonker, Schelto Kruijff, Milou Noltes, Pieter Steinkamp, Deborah Wright, Lukman Abdur-Rahman, Adesoji Ademuyiwa, Adewale Adisa, Babatunde Osinaike, Justina Seyi-Olajide, Omolara Williams, Emmanuel Williams, Sofija Pejkova, Zainab Al Balushi, Raza Sayyed, Mustafa Abo Mohsen, Sadi A Abukhalaf, Moises Cukier, Hugo Gomez-Fernandez, Sebastian Shu Yip, Ximena Paola Vasquez Ojeda, Marie Dione Sacdalan, Piotr Major, José Azevedo, Miguel F Cunha, Ahmad Zarour, Eduard-Alexandru Bonci, Ionut Negoi, Sergey Efetov, Viktor Kochetkov, Andrey Litvin, Jc Allen Ingabire, Georges Bucyibaruta, Ntirenganya Faustin, Sosthene Habumuremyi, Alphonsine Imanishimwe, Haragirimana Jean de Dieu, Emmanuel Munyaneza, Isaie Ncogoza, Ehab Alameer, Abdourahmane Ndong, Dejan Radenkovic, Min Hoe Chew, Frederick Koh, James Ngu, Arpád Panyko, Uros Bele, Jurij Aleš Košir, Hassan Daoud, Ana Maria Minaya Bravo, Umesh Jayarajah, Dakshitha Wickramasinghe, Mohammed Elmujtba Adam Essa Adam, Martin Rutegård, Malin Sund, Michel Adamina, Eleftherios Gialamas, Karoline Horisberger, Muhammad Alshaar, Abel Huang, Varut Lohsiriwat, Shane Charles, Haithem Jlassi, Arda Isik, Hervé Monka Lekuya, Slava Kopetskyi, Hayder Alsaadi, Sattar Alshryda, Osaid Alser, Brittany Bankhead-Kendall, Kerry Breen, Hassan Mashbari, Fernando Bonilla Cal, Hamza Al-Naggar, Mayaba Maimbo, Dennis Mazingi, Tom Abbott, Melika Akhbari, Ruth Benson, Shivam Bhanderi, Bruce Biccard, Edward Caruana, Sohini Chakrabortee, Reema Chapatwala, Ainhoa Costas-Chavarri, Andreas K Demetriades, Anant Desai, Salomone Di Saverio, Thomas Drake, John Edwards, Jonathan Evans, Marco Fiore, Samuel Ford, Christina Fotopoulou, Alexander Fowler, Kaori Futaba, Ian Ganly, Harelimana Grace James, Ewen Griffiths, Alessandro Gronchi, Peter Hutchinson, Gabriella Yael Hyman, Joseph Incorvia, Ritu Jain, Michael Jenkinson, Tabassum Khan, Stephen Richard Knight, Angelos Kolias, Søren Kudsk-Iversen, Tsun Yu Kwan, Elaine Leung, Julio Mayol, Siobhan McKay, John G Meara, Emily Mills, Susan Moug, Akshay Patel, Roberto Perinotti, Henry E Rice, Keith Roberts, Andrew Schache, Richard Shaw, Neil Smart, Matthew Stephens, Grant D Stewart, Ella Teasdale, Peter Vaughan-Shaw, Raghavan Vidya, Naomi Wright, Natalie Zimmelman, Ervis Agastra, Dariel Thereska, Sergio Martin Lucchini, Veronica Laudani, Carina Chwat, Ivana Ines Pedraza Salazar, Diana Alejandra Pantoja Pachajoa, Agustin Duro, José Alfredo Calderón Arancibia, Giuliana D'Aulerio, Nagendra Dudi-Venkata, Natasha Egoroff, Shebani Farik, Natalie Lott, Jana-Lee Moss, Sarah Rennie, Lorwai Tan, Uyen Giao Vo, David Watson, David Watters, Tim Bright, Paul Hollington, Xuanyu Zhou, Hidde M Kroon, Anthony Farfus, John Barker, Eleanor Watson, Sean Stevens, Haider Latif, Amanda Caroline Dawson, Alwin Chuan, Vijayaragavan Muralidharan, Enoch Wong, Travis Ackermann, Maurizio Pacilli, Russell Hodgson, Alexander Heriot, Peter Choong, Wendy Brown, Surjit Lidder, Justin Yeung, Luke Traeger, Guillermo Regalo, Ralph Gourlay, Sarit Badiani, Cherry Koh, Soni Putnis, Fayza Haider, Ashrarur Rahman Mitul, Niels Komen, Bert Dhondt, Serge Cappeliez, Manon Pigeolet, Martijn Schoneveld, Jasper Stijns, Wouter Oosterlinck, Nicolas Flamey, Cyrille Kpangon, Mouhamed Agbadebo, S Mèvo Romaric Tobome, Aldo Vieira Barros, Samuel Aguiar Júnior, Heloisa Galvão do Amaral Campos, Jefferson Gross, Felipe José Fernandez Coimbra, Luiz Paulo Kowalski, Fabiana Makdissi, Suely Nakagawa, Joao Pedreira Duprat Neto, Jose Guilherme Vartanian, Guilherme Yazbek, Stenio C Zequi, Ronald Flumignan, Natalia Jaworska, Angela Dell, Harsha Shanthanna, Abdollah Behzadi, Carolyn Nessim, Michelle Mozel, Pascal St-Germain, Crispin Russell, Gary Groot, Najib Safieddine, Duminda Wijeysundera, Antoine Eskander, Sami Chadi, Shawn MacKenzie, Alana Flexman, Fernando Heredia, Julio Villanueva, Sofia Waissbluth, Roberto Macchiavello, Mario I Escudero, Tyare Fuentes, Ximena Mimica, Dinimo Bolivar Saenz, Lina Caicedo, Juan Pablo Alzate, Joaquin Luna, Nestor Fabian Pedraza Alonso, Camilo Ortiz Silva, Juliana Rodriguez, Liliana Silva-Igua, Martha Luz Torres, Lina María Trujillo, Albaro José Nieto Calvache, Julián Balanta-Melo, Rafael Figueroa-Casanova, Oscar-Julián García-Montoya, Carlos Andres Marulanda Toro, Marcela Velez Botero, Maria Clara Mendoza Arango, Eneida Diaz Martinez, Valentina Gutiérrez Perdomo, Emileth 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Mege, Clement Jeandel, Emilie Duchalais, Pierre-Alban Bouche, Gilles Manceau, Célia Crétolle, Erik Hervieux, Noémie Girard, Agathe Seguin-Givelet, Sebastien Gaujoux, Belinda De Simone, Matthieu Boisson, Damien Bergeat, Fabien Fredon, Francesco Nappi, Radwan Kassir, Aurélien Scalabre, Federico Migliorelli, Anne-Cecile Ezanno, Barbara Seeliger, Charlotte Vaysse, Helene Charbonneau, Vincent Misrai, Olivier Abbo, Martina Aida Angeles, Laurent Brunaud, Ali Modabber, Sebastian Wolf, Carsten Kamphues, Philipp Höhn, Tim R Glowka, Alexander Christopher Rokohl, Ulrich Bork, Georg Fluegen, Raymund E Horch, Andrea Schmedding, Andreas Schnitzbauer, Helge Eberbach, Daniel Schlager, Fritz Spelsberg, Lena Keppler, Andreas Hecker, Susanne Wolfer, Ulrich Ronellenfitsch, Christine Nitschke, Christian Peiper, Ibrahim Hakami, Stefan Welter, Karine Nikolaieva, Andreas Roth, Judith Lindert, Konstantinos Gousias, Anke Rissmann, Valerie Catherine Linz, Nuh Rahbari, Marie-Claire Rassweiler-Seyfried, Anna Eleonora Gut, Jens Gempt, Daniel Reim, Arthur Wagner, Alexander M Keppler, Mircea Gabriel Stoleriu, Tim Saier, Josef Stadler, Julia Christina Kaiser, Stefan M Brunner, Karin Pfister, Jonas Herzberg, Kai Nowak, Tobias Reinhard, Gregor A Stavrou, Alfred Königsrainer, Christian Konrads, Markus Quante, Simon Laban, Silke von Pusch, Markus Hirschburger, Johannes Doerner, Armin Wiegering, Ekaterini Christina Tampaki, Alitza Gutiérrez Ruiz, Alejandra Rodas, Ana Lucía Portilla, Jacqueline Carrera, Amalia Barrios Duarte, Megan Lowey, Sabrina Barillas, Atul Suroy, Dhaivat Vaishnav, Raghunandan Gorantlu Chowdappa, Irappa Madabhavi, Dhananjaya Bhat, Sunil Kumar Venkatappa, Sumit Thakar, Kavitha Jain, Aruna Kumar, Manoj Nagar, Tushar Mishra, Arunkumar Sekar, Anand Gupta, Lileswar Kaman, Madhivanan Karthigeyan, Manjul Tripathi, Ashwin Rammohan, Sudheer Othiyil Vayoth, Anupama Rajanbabu, Anbukkani Subbian, Rahul Gupta, Monish Raut, Nissi Evelyn, R Lavanya Kannaiyan, Anil Matai, Sanjeev Misra, Vishal Bhende, Sathish Muthu, Indranil Ghosh, Abhishek Sharma, Ankur Bajaj, Shiv Rajan, Gaurav Agarwal, Pranay Pawar, Philip Alexander, M Vijayakumar Vijayakumar, Zeeshan Hameed, L Badareesh, Navneet Kumar Chaudhry, Lipika Baliarsing, Satish Dharap, Amruta Kulkarni, Yuvaraja Thyavihally, Rahul Deo Sharma, C S Pramesh, Rajesh Soni, Surya Kumar Dube, Shilpa Sharma, Harvinder Singh, Lovenish Bains, Rahul Ghodke, Ashwani Kumar, Vivek Sodhai, Suvendu Maji, Somprakas Basu, Chandrashekhar Mahakalkar, Ravi Kannan, Asif Mehraj, N Ranganath, Ashish Phadnis, I Yadev, Alfie Kavalakat, Rohin Mittal, Karthik Chandra Vallam, Hamed Akhavizadegan, Esmaeil Rezghi Maleki, Naser Yousefzadeh Kandevani, Hilary Ikele, Catherine McNestry, Christina Fleming, Stephen O'Brien, Sami Abd Elwahab, Niall Davis, Mohsen Javadpour, Brendan McDonnell, Clare O Connor, Jarlath Bolger, Cillian Clancy, Stefanie M Croghan, Noel Donlon, Carolyn Cullinane, Ben Creavin, Muheilan Muheilan, Helen Earley, Syed Mohammad Umar Kabir, Muhammad Fahadullah, Éanna Ryan, Tara Connelly, Daisuke Hashimoto, Majdi Ali Alqudah, Amer Alajalen, Rand Y Omari, Abdulrahman Qasem, Yazan Alawneh, Amer Ahmad, Omar Aladawi, Bourhan Alrayes, Hanan Haidar, Shatha Husain, Faisal Qassem, Adnan Sumadi, Ala'a Abu Salhiyeh, Balqees Mahmoud Al-Manaseer, Zaid Alsunna, Hazim Ra'ed, Faten Reyad Bani Hamad, Amro Abuleil, Elmi Ahmed Mohamed Jimaale, Marah Abu-Mehsen, Noor Olaywah, Omar Wafi, Hazim Ababneh, Luai Abu-Ismail, Almu'atasim Khamees, Ahmad Alkhatib, Raikhan Bolatbekova, Mukhtar Kulimbet, Talgat Nurgozhin, Timur Saliev, Baurzhan Zhussupov, Ydyrys Almabayev, Dilyara Kaidarova, Khalil Tamoos, Ahmed Aqeelah, Alsnosy Abdullah Khalefa Mohammed, Faraj Al Maadany, Ghadah Alkadeeki, Milad Gahwagi, Wafa Aldressi, Mohamed Amnaina, Arowa Hassan Abdulrahman Alansari, Akram Alkaseek, Ghozlan Yagoub, Anass Ben Amer, Marwa Salem, Ayman Almugaddami, Dania Burgan, Mohammed Abdelkabir, Khayriyah Alshareef, Rayet Al Islam Ben Jouira, Ayman Meelad, Ahmad Bouhuwaish, Sumayya Essayah Dwaga, Houda Khalifa, Bushray Almiqlash, Taha Suliaman, Mohammed Alawami, Fras Elhajdawe, Hajir Aboazamazem, Ibrahim Ellojli, Ahmed Msherghi, Ismail Ali Saleh, Mohammed Alayan, Marcel Didier Ndayishyigikiye, Akutu Munyika, Philipp Plarre, David W Borowski, Cameron Wells, Rebecca Teague, Brodie Elliott, David Kieser, Omar Mohyieldin, Nick McIntosh, Cheyaanthan Haran, Jasmin King, Jeong Ha, Matthew James McGuinness, Opeoluwa Adesanya, Julius Olaogun, Akinola Akinmade, Kefas Bwala, Peter Agbonrofo, Akinwale Afolabi, Usang Usang, Sebastian Ekenze, Samson Olori, Taiwo Akeem Lawal, Abiodun Okunlola, Stephen Kache, Danjuma Sale, Lofty-John Anyanwu, Chukwuma Okereke, Musliu Adetola Tolani, Venko Filipce, Lazar Todorovic, Sotir Stavridis, John George Massoud, Sareyah Alsibai, Rizwan Sultan, Humera Naz Altaf, Abu Bakar Hafeez Bhatti, Shahzad Hussain Waqar, Aliya Aziz, Asad Ali Kerawala, Lajpat Rai, Mariyah Anwer, Aiman Tariq, Bushra Ayub, Sami Ullah Niazi, Muhammad Yasir Naseem, Muhammad Zeeshan Sarwar, Muhammad Imran Khokhar, Imdad Ahmad Zahid, Haroon Javaid Majid, Nabila Talat, Muhammad Asif, Muhammad Hamid Chaudhary, Umer Farooq, Siddique Ahmad, Waleed Mabood, Syed Imran Bukhari, Muhammad Tariq, Eesha Yaqoob, Saad Javed, Muhammad Usman Malik, Hassan Nawaz Yaqoob, Glenda Marina Falcon Pacheco, Robinson Mas Melendez, Arazzelly Del Pilar Paucar Urbina, Jose Rios Chiuyari, Carlos Eduardo Otiniano Alvarado, Lorena Fuentes Rivera Lau, Giuliano Borda-Luque, Milagros Niquen-Jimenez, Claudia Arias, Sergio Zegarra, Jenner Betalleluz Pallardel, Regina Amparo Ugarte Oscco, Gian Mendiola, Yahaira Tatiana Carpio Colmenares, Carlos Shiraishi Zapata, Maria Rosa Ortiz, Filipe Castro Borges, Octavio Viveiros, Pedro Serralheiro, Paulo Santos-Costa, Filipa Mendes, Miguel Rocha Melo, Paulo Cardoso, Ana Soares, Rita Gonçalves Pereira, Nelson Silva, André Caiado, Maria Luís Sacras, Pedro Azevedo, Rui Almeida-Reis, João Oliveira, Jorge Nogueiro, Mafalda Sampaio-Alves, Luciana Cidade Costa, Catarina Baía, Ana Cláudia Deus, Rita Branquinho, André Marçal, André Tojal, Silviu Tiberiu Makkai-Popa, Aurel Mironescu, Florin Grama, Elena Adelina Toma, Daniela Filipescu, Nicolae Bacalbasa, Natalia Motas, Sebastian Ionescu, Octav Ginghina, Radu Costea, Narcis Octavian Zarnescu, Radu Drasovean, Mihail-Gabriel Dimofte, Vlad Porumb, Mikhail Kirov, Yegor Molitvin, Vadim Pykhteev, Marianna Raevskaya, Aleksandr Butyrskii, Mushabab Alshahrani, Azah Althumairi, Nasser Alzerwi, Ahmed Al Ameer, Tariq Madkhali, Abddulrahman Saleh Almulhim, Salman Ghazwani, Abdu Ayoub, Othman Iskander, Mohammed Ghunaim, Mohammed Alharthi, Turki M Alzaidi, Mohammad Alyami, Abdulrahman Al Amri, Abdullah AlFakhri, Amal Alhefdhi, Sharfuddin Chowdhury, Thamer Nouh, Ameen Alshehri, Abdulrahman Alzahrani, Yousef Alalawi, Selmy Awad, Ibrahima Konate, Jacques Tendeng, Nan Zun Teo, Sabra Aqil, Cristina Barrena López, Ana Sánchez Mozo, Antonio Rodriguez Infante, Patricia Caja Vivancos, Mikel Prieto, Igor Alberdi San Roman, Laura Gomez Fernandez, Josep Maria Muñoz Vives, Anna Carreras-Castañer, Berta Díaz-Feijoo, Ramon Sieira-Gil, Victor Turrado-Rodriguez, Anna Sánchez López, Santiago Sánchez-Cabús, Marta Jimenez Toscano, MªPilar Canals Sin, Saura García Laura, Oriol Martin Sole, Pedro Palazon Bellver, Sonia Pérez-Bertólez, Jordi Prat-Ortells, Mireia Riba Martínez, Josep Rubio-Palau, Xavier Tarrado, Jorge Nuñez, Veronica Alonso Mendoza, Coro Bescós, Eloy Espin-Basany, Martin Espinosa-Bravo, Daniel Gil-Sala, Susana González-Suárez, Nuria Montferrer Estruch, Lucia Porteiro Mariño, Ana Rodríguez-Tesouro, Fabian Rojas Portilla, M Pilar Tormos Pérez, Inmaculada Vives, Unai Garcia De Cortazar, Kiara Tudela, Aitor Landaluce-Olavarria, Mercedes Estaire Gómez, Jorge Almoguera, Bakarne Ugarte-Sierra, Virginia Jimenez, Marta Bertrand, Laura Cárdenas Puiggrós, Olga Delisau-Puig, Jorge Garcia-Adamez, David Julià Bergkvist, Eloy Maldonado-Marcos, Lucia Diego García, Marta Roldón Golet, Iván Soto-Darias, Aida Cristina Rahy-Martín, Diego Enjuto, Adolfo Ramos-Luengo, Juan Delgado Fernandez, Carolina Lugo Duarte, Cristina Ojeda Thies, Lucila Marquez, Diana Crego Vita, Jana Dziakova, Jorge Caño Velasco, Olga Mateo-Sierra, Begoña Quintana-Villamandos, Cristina Rey Valcarcel, Javier Rio, Laura Román García de León, Marcello Di Martino, Jorge Prada, Javier Serrano González, Manuel Losada, Jose Tomas Castell Gomez, Ramon Corripio-Sanchez, Alexander Forero-Torres, José Manuel Morales-Puebla, Hanna Perez-Chrzanowska, Santiago Valderrabano Gonzalez, Alvaro Yebes, Ignacio Zapardiel, Manuel Diez Alonso, Nelson Morales Palacios, Alberto Cabañero Sánchez, Fátima Sánchez Fernández, Alfredo Abad Gurumeta, Ane Abad-Motos, Fernando Corella, Javier Ripollés-Melchor, Rosa Sanz-Gonzalez, Marta Alcaraz Fuentes, Maria Teresa Fernández Martín, Pablo Calvo Espino, Milagros Carrasco Prats, Antonio-José Fernández-López, Damián García Escudero, Vanesa Garcia Soria, Jesús Aarón Martínez Alonso, Miguel Ruiz-Marín, Beatriz Gómez Pérez, Joaquin Moya-Angeler, Daniel Fernández Martínez, Heura Llaquet Bayo, Enrique Colás-Ruiz, Susana Bella Romera, M Teresa Gavaldà Pellicé, Misericòrdia Jordà Solé, Enrique Jose Ruiz Velasquez, Bernardo Núñez, Raul Jimenez, Jon Zabaleta, Maria Jose González-Gimeno, Irene Ortega Vázquez, Antonio Perez Ferrer, Rubén Martín-Láez, Marcelo Moreno Suarez, Miguel Angel Freiria Eiras, Irene Ramallo-Solís, Juan-Carlos Gomez-Rosado, Jose Ramon Oliver Guillen, Mar Achalandabaso Boira, Juan Carlos Catalá Bauset, Julio Domenech, Rafael Badenes, Juan Carlos Bernal-Sprekelsen, Jorge Sancho-Muriel, Beatriz De Andrés-Asenjo, Francisco J Tejero-Pintor, Marc Vallve-Bernal, Alba Vazquez Melero, Laura Sánchez Blasco, Jorge Escartin, Victoria Duque Mallén, Selvaratnam Srishankar, Charitha Sooriyabandara, Oshan Basnayake, Nalaka Gunawansa, Prabuth Dulanjan Weeraddana, Thanusan Vimalakanthan, Shanthamoorthy Gishanthan, Pramodh Chandrasinghe, Marc-Olivier Sauvain, Ahmad Ghazal, Yusra Al-Sabbagh, Turki Alhassoun, Sara Maa Albared, Antoine Naem, Hareth Alnahr, Ghassan Jisry, Ali Hammed, Okedi Francis Xaviour, Gaston Turinawe, Isaac Mubezi, Franck K Sikakulya, Andrew Kakeeto, Wilberforce M Kabweru, Ronald Kiweewa, Paul Matovu, Otolia Isaac, Mohamed Mashhour, Amin El Helw, Safeena Kherani, Awadelkarim Mohamed, Ferial Mohamed Ali Abbas, Diary Mohammed, Ehab Aldlyami, Rakesh Kundra, Antony Louis Rex Michael, Kareem S Khalil, Rachel Dbeis, Shafaque Shaikh, Jenny Ferry, Aiman Jamal, Haleema Siddique, Rishi Das, Nikhil Ponugoti, Pornjittra Rattanasirivilai, Asma Sultana, Frances Mosley, Matthew Chan, Antony Bateman, Gareth Davies-Jones, Fanourios Georgiades, Navid Ahmadi, Aman Coonar, Mariam Baig, Chetan Khatri, Arthika Surendran, Julian Sonksen, Robert Sinnerton, Caitlin Brennan, Gemma Faulkner, Michael Greenhalgh, Hannah Emerson, Kiran Singisetti, Joshua Totty, Michael Wilson, Terence Lo, Harriet Corbett, Ijeoma Okonkwo, Gill Arbane, Cyrus Kerawala, Chetan Parmar, Michael Bath, Funlayo Odejinmi, Jayesh Sagar, Rishi Talwar, Samuel Newman, John Hammond, John Moir, Natalie Duric, Tamas Szakmany, Ahmar Iftikhar Talib, Mina Youssef, Christopher Lewis-Lloyd, Mariam Lami, Khurram Ayub, Benjamin Dean, Supriya Balasubramanya, Sathya Lakpriya, Luke Rogers, Paul Turner, Mark Maher, Kohila Sigamoney, Jihène El Kafsi, John Hardie, David Johnson, Christin Henein, Marianne Hollyman, Ketan Agarwal, Simon Powell, Govind Singh Chauhan, Rakesh Patel, Joel Gagnier, Heather Carmichael, Aurora, Kristofor A Olson, Eric Etchill, Sameer Hirji, Matthew Naunheim, Frederick Drake, Caroline Reinke, Anna Alecci, Dennis Vaysburg, Jennifer Rodriquez, Emily Shih, Vin Shen Ban, Julia Coleman, Krista Kaups-Fresno, Emmanouil Giorgakis, Maggie DiNome, Neal Bhutiani, Omar Alnachoukati, Taylor Aiken, Thomas Diehl, Ankush Gosain, Rishi Rattan, Muhammad Owais Abdul Ghani, Nensi Melissa Ruzgar, Anna Liveris, Nina Glass, Charu Paranjape, Theresa Chin, Antonio Meola, Kristina Nicholson, John Squiers, Stephanie Lueckel, Janani Reisenauer, Rachael Callcut, Ahmed Mansour, Allison Berndtson, Lucy Kornblith, Sara Seegert, Paulo Martins, Mohammed Al-Shehari, Ibrahim Al-Raimi, Allan Ngulube, Maphios Siamuchembu, Willard Mushiwokufa, Busisiwe Mlambo, Simbarashe Chinyowa, Enton Bollano, Kostandin Gjyli, Jola Kerpaci, Enxhi Vrapi, Lorena Zijaj, Bahraoui Djahida, Belabbes Fatima Zohra, Kouidri Khadidja, Oussama Bali, Nassim Benallel, Ismahene Lalmi, Meriem Abdoun, Nesrine Aouabed, Souad Bouaoud, Kamel Bouchenak, Assia Haif, Zineddine Soualili, Joaquin Bastet, Agustín Bianco, Daniel Capitaine, Jorge Centeno Lozada, Carlos Esquivel, Rodrigo Figueroa, Manuel Garcia, Pablo Martín García, José Ignacio Gerchunoff, Fernando Martinez Iascano, Jose Mondino, María Emilia Muriel, Carmignani Pablo, Martin Passadore, Alejandra Tornini, Rogelio Traverso, Lara Vargas, Gerardo Zanoni, Norberto Berber, Estefanía Cotta, Marcela Di Vincenzo, Esteban Sebastian Gallino, 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Kache, Danjuma Sale, Lofty-John Anyanwu, Chukwuma Okereke, Musliu Adetola Tolani, Venko Filipce, Lazar Todorovic, Sofija Pejkova, Sotir Stavridis, John George Massoud, Sareyah Alsibai, Rizwan Sultan, Humera Naz Altaf, Abu Bakar Hafeez Bhatti, Shahzad Hussain Waqar, Aliya Aziz, Asad Ali Kerawala, Lajpat Rai, Mariyah Anwer, Aiman Tariq, Bushra Ayub, Sami Ullah Niazi, Muhammad Yasir Naseem, Muhammad Zeeshan Sarwar, Muhammad Imran Khokhar, Imdad Ahmad Zahid, Haroon Javaid Majid, Nabila Talat, Muhammad Asif, Muhammad Hamid Chaudhary, Umer Farooq, Siddique Ahmad, Waleed Mabood, Syed Imran Bukhari, Muhammad Tariq, Eesha Yaqoob, Saad Javed, Saad Javed, Muhammad Usman Malik, Hassan Nawaz Yaqoob, Moises Cukier, Glenda Marina Falcon Pacheco, Robinson Mas Melendez, Arazzelly Del Pilar Paucar Urbina, Jose Rios Chiuyari, Carlos Eduardo Otiniano Alvarado, Lorena Fuentes Rivera Lau, Giuliano Borda-Luque, Milagros Niquen-Jimenez, Claudia Arias, Sergio Zegarra, Jenner Betalleluz Pallardel, Regina Amparo Ugarte Oscco, Gian Mendiola, Yahaira Tatiana Carpio Colmenares, Carlos Shiraishi Zapata, Maria Rosa Ortiz, Marie Dione Sacdalan, Piotr Major, Filipe Castro Borges, Octavio Viveiros, Pedro Serralheiro, Paulo Santos-Costa, Filipa Mendes, Miguel Rocha Melo, Paulo Cardoso, Ana Soares, José Azevedo, Rita Gonçalves Pereira, Nelson Silva, André Caiado, Maria Luís Sacras, Pedro Azevedo, Rui Almeida-Reis, Miguel F Cunha, João Oliveira, Jorge Nogueiro, Mafalda Sampaio-Alves, Luciana Cidade Costa, Catarina Baía, Ana Cláudia Deus, Rita Branquinho, André Marçal, André Tojal, Ahmad Zarour, Ahmad Zarour, Silviu Tiberiu Makkai-Popa, Aurel Mironescu, Florin Grama, Elena Adelina Toma, Ionut Negoi, Daniela Filipescu, Nicolae Bacalbasa, Natalia Motas, Sebastian Ionescu, Octav Ginghina, Radu Costea, Narcis Octavian Zarnescu, Radu Drasovean, Eduard-Alexandru Bonci, Mihail-Gabriel Dimofte, Vlad Porumb, Mikhail Kirov, Yegor Molitvin, Andrey Litvin, Vadim Pykhteev, Marianna Raevskaya, Sergey Efetov, Aleksandr Butyrskii, Mushabab Alshahrani, Azah Althumairi, Nasser Alzerwi, Ahmed Al Ameer, Ahmed Al Ameer, Tariq Madkhali, Abddulrahman Saleh Almulhim, Salman Ghazwani, Abdu Ayoub, Othman Iskander, Mohammed Ghunaim, Mohammed Alharthi, Turki M Alzaidi, Azah Althumairi, Mohammad Alyami, Abdulrahman Al Amri, Azah Althumairi, Abdullah AlFakhri, Amal Alhefdhi, Sharfuddin Chowdhury, Thamer Nouh, Ameen Alshehri, Abdulrahman Alzahrani, Yousef Alalawi, Selmy Awad, Ibrahima Konate, Abdourahmane Ndong, Jacques Tendeng, Nan Zun Teo, Frederick Koh, Jurij Aleš Košir, Uros Bele, Sabra Aqil, Cristina Barrena López, Ana Sánchez Mozo, Antonio Rodriguez Infante, Patricia Caja Vivancos, Mikel Prieto, Igor Alberdi San Roman, Laura Gomez Fernandez, Josep Maria Muñoz Vives, Anna Carreras-Castañer, Berta Díaz-Feijoo, Ramon Sieira-Gil, Victor Turrado-Rodriguez, Anna Sánchez López, Santiago Sánchez-Cabús, Marta Jimenez Toscano, MªPilar Canals Sin, Saura García Laura, Oriol Martin Sole, Pedro Palazon Bellver, Sonia Pérez-Bertólez, Jordi Prat-Ortells, Mireia Riba Martínez, Josep Rubio-Palau, Xavier Tarrado, Jorge Nuñez, Veronica Alonso Mendoza, Coro Bescós, Eloy Espin-Basany, Martin Espinosa-Bravo, Daniel Gil-Sala, Susana González-Suárez, Nuria Montferrer Estruch, Jorge Nuñez, Lucia Porteiro Mariño, Ana Rodríguez-Tesouro, Fabian Rojas Portilla, M Pilar Tormos Pérez, Inmaculada Vives, Unai Garcia De Cortazar, Kiara Tudela, Aitor Landaluce-Olavarria, Mercedes Estaire Gómez, Jorge Almoguera, Bakarne Ugarte-Sierra, Virginia Jimenez, Marta Bertrand, Laura Cárdenas Puiggrós, Olga Delisau-Puig, Jorge Garcia-Adamez, David Julià Bergkvist, Eloy Maldonado-Marcos, Lucia Diego García, Marta Roldón Golet, Iván Soto-Darias, Aida Cristina Rahy-Martín, Diego Enjuto, Adolfo Ramos-Luengo, Juan Delgado Fernandez, Carolina Lugo Duarte, Cristina Ojeda Thies, Lucila Marquez, Diana Crego Vita, Jana Dziakova, Ana Maria Minaya Bravo, Jorge Caño Velasco, Olga Mateo-Sierra, Begoña Quintana-Villamandos, Cristina Rey Valcarcel, Javier Rio, Laura Román García de León, Marcello Di Martino, Jorge Prada, Javier Serrano González, Manuel Losada, Jose Tomas Castell Gomez, Ramon Corripio-Sanchez, Alexander Forero-Torres, José Manuel Morales-Puebla, Hanna Perez-Chrzanowska, Santiago Valderrabano Gonzalez, Alvaro Yebes, Ignacio Zapardiel, Manuel Diez Alonso, Nelson Morales Palacios, Alberto Cabañero Sánchez, Fátima Sánchez Fernández, Alfredo Abad Gurumeta, Ane Abad-Motos, Fernando Corella, Javier Ripollés-Melchor, Rosa Sanz-Gonzalez, Marta Alcaraz Fuentes, Maria Teresa Fernández Martín, Pablo Calvo Espino, Milagros Carrasco Prats, Antonio-José Fernández-López, Damián García Escudero, Vanesa Garcia Soria, Jesús Aarón Martínez Alonso, Miguel Ruiz-Marín, Beatriz Gómez Pérez, Joaquin Moya-Angeler, Daniel Fernández Martínez, Heura Llaquet Bayo, Enrique Colás-Ruiz, Susana Bella Romera, M Teresa Gavaldà Pellicé, Misericòrdia Jordà Solé, Enrique Jose Ruiz Velasquez, Bernardo Núñez, Raul Jimenez, Jon Zabaleta, Maria Jose González-Gimeno, Irene Ortega Vázquez, Antonio Perez Ferrer, Rubén Martín-Láez, Marcelo Moreno Suarez, Miguel Angel Freiria Eiras, Irene Ramallo-Solís, Juan-Carlos Gomez-Rosado, Jose Ramon Oliver Guillen, Mar Achalandabaso Boira, Juan Carlos Catalá Bauset, Julio Domenech, Rafael Badenes, Juan Carlos Bernal-Sprekelsen, Jorge Sancho-Muriel, Beatriz De Andrés-Asenjo, Francisco J Tejero-Pintor, Marc Vallve-Bernal, Alba Vazquez Melero, Laura Sánchez Blasco, Jorge Escartin, Victoria Duque Mallén, Selvaratnam Srishankar, Umesh Jayarajah, Charitha Sooriyabandara, Oshan Basnayake, Nalaka Gunawansa, Dakshitha Wickramasinghe, Prabuth Dulanjan Weeraddana, Thanusan Vimalakanthan, Shanthamoorthy Gishanthan, Pramodh Chandrasinghe, Eleftherios Gialamas, Marc-Olivier Sauvain, Ahmad Ghazal, Yusra Al-Sabbagh, Turki Alhassoun, Sara Maa Albared, Antoine Naem, Hareth Alnahr, Ghassan Jisry, Ali Hammed, Arda Isik, Okedi Francis Xaviour, Gaston Turinawe, Isaac Mubezi, Franck K Sikakulya, Andrew Kakeeto, Wilberforce M Kabweru, Hervé Monka Lekuya, Ronald Kiweewa, Herman Lule, Paul Matovu, Otolia Isaac, Mohamed Mashhour, Amin El Helw, Sattar Alshryda, Safeena Kherani, Awadelkarim Mohamed, Ferial Mohamed Ali Abbas, Diary Mohammed, Ehab Aldlyami, Rakesh Kundra, Mohamed Mashhour, Mohamed Mashhour, Antony Louis Rex Michael, Hayder Alsaadi, Kareem S Khalil, Rachel Dbeis, Shafaque Shaikh, Jenny Ferry, Aiman Jamal, Haleema Siddique, Rishi Das, Nikhil Ponugoti, Sivesh K Kamarajah, Pornjittra Rattanasirivilai, Asma Sultana, Frances Mosley, Matthew Chan, Antony Bateman, Gareth Davies-Jones, Fanourios Georgiades, Grant D Stewart, Navid Ahmadi, Aman Coonar, Mariam Baig, Chetan Khatri, Arthika Surendran, Julian Sonksen, Robert Sinnerton, Caitlin Brennan, Gemma Faulkner, Michael Greenhalgh, Hannah Emerson, Kiran Singisetti, Joshua Totty, Michael Wilson, Terence Lo, Harriet Corbett, Ijeoma Okonkwo, Gill Arbane, Kariem El-Boghdadly, Cyrus Kerawala, Chetan Parmar, Tom Abbott, Michael Bath, Funlayo Odejinmi, Jayesh Sagar, Rishi Talwar, Samuel Newman, John Hammond, John Moir, Natalie Duric, Tamas Szakmany, Ahmar Iftikhar Talib, Mina Youssef, Christopher Lewis-Lloyd, Christopher Lewis-Lloyd, Mariam Lami, Khurram Ayub, Benjamin Dean, Supriya Balasubramanya, Sathya Lakpriya, Luke Rogers, Paul Turner, Mark Maher, Kohila Sigamoney, John Edwards, Jihène El Kafsi, John Hardie, David Johnson, Christin Henein, Marianne Hollyman, Ketan Agarwal, Simon Powell, Govind Singh Chauhan, Rakesh Patel, Joel Gagnier, Heather Carmichael, Aurora, Kristofor A Olson, Eric Etchill, Joseph Incorvia, Sameer Hirji, Matthew Naunheim, Frederick Drake, Haytham Kaafarani, Caroline Reinke, Anna Alecci, Dennis Vaysburg, Jennifer Rodriquez, Emily Shih, Vin Shen Ban, Julia Coleman, Henry E Rice, Krista Kaups-Fresno, Emmanouil Giorgakis, Maggie DiNome, Neal Bhutiani, Omar Alnachoukati, Brittany Bankhead-Kendall, Taylor Aiken, Thomas Diehl, Ankush Gosain, Rishi Rattan, Muhammad Owais Abdul Ghani, Nensi Melissa Ruzgar, Anna Liveris, Nina Glass, Charu Paranjape, Theresa Chin, Antonio Meola, Kristina Nicholson, John Squiers, Stephanie Lueckel, Janani Reisenauer, Rachael Callcut, Ahmed Mansour, Allison Berndtson, Lucy Kornblith, Sara Seegert, Paulo Martins, Hamza Al-Naggar, Mohammed Al-Shehari, Ibrahim Al-Raimi, Allan Ngulube, Maphios Siamuchembu, Willard Mushiwokufa, Busisiwe Mlambo, Simbarashe Chinyowa, Ervis Agastra, Enton Bollano, Kostandin Gjyli, Dariel Thereska, Irida Dajti, Jola Kerpaci, Enxhi Vrapi, Lorena Zijaj, Bahraoui Djahida, Belabbes Fatima Zohra, Kouidri Khadidja, Oussama Bali, Nassim Benallel, Ismahene Lalmi, Meriem Abdoun, Nesrine Aouabed, Souad Bouaoud, Kamel Bouchenak, Assia Haif, Zineddine Soualili, Joaquin Bastet, Agustín Bianco, Daniel Capitaine, Jorge Centeno Lozada, Carlos Esquivel, Rodrigo Figueroa, Manuel Garcia, Pablo Martín García, José Ignacio Gerchunoff, Fernando Martinez Iascano, Jose Mondino, María Emilia Muriel, Carmignani Pablo, Martin Passadore, Alejandra Tornini, Rogelio Traverso, Lara Vargas, Gerardo Zanoni, Norberto Berber, Estefanía Cotta, Marcela Di Vincenzo, Esteban Sebastian Gallino, Cecilia Gigena, Bianca Grassano, Veronica Laudani, Ignacio Lugones, Constanza Madrid, Maximiliano Maricic, Antonio Alberto Martinez, Andres Rosso, Pablo Scher, Sofia Tachella, Damaris Idara Anabel Zezular, Carla Abuawad, Agustin Albani Forneris, Carola Allemand, Laura Gisela Alvarez Calzaretta, Luis Boccalatte, Jorge G Boretto, Rocio Boudou, Rodrigo Brandariz, Martin Buljubasich, Arturo Burchakchi, Martin Buttaro, Juan Pablo Campana, Virginia Cano Busnelli, Tomas Carminatti, Agustina Florencia Castro Lalín, Julian Cereghini, María Sol Crespi Amor, Roberto Sebastián Croattini, Maria Sol Fernandez, Marcelo Figari, Uriel Fraidenraij, Diego Gallegos, Agustín Maria García-Mansilla, Marcos Gonzalez, Matias Ignacio Gonzalez, Esteban Gonzalez Salazar, Jeremias Goransky, Guillermo Hernandez Gauna, Felipe Higuera, Fernando Holc, Esteban Gabriel Jauregui, Juan Larrañaga, Juan Liyo, Lionel Llano, Pablo Lobos, Emilia Luzzi, Gustavo Mastroianni, Santiago Miguel Mata-Suarez, Horacio F Mayer, Santiago Mc Loughlin, Efrain Mendoza, Ricardo Esteban Mentz, Pedro Mercado, Pablo Moyano, Florencia Noll, Diego Odetto, Agustina Rene Oliva, Rafael Perez Vidal, Catalina Poggi, Eduardo Jorge Premoli, María Lourdes Ramos, Patricio Rosas, Luciano Rossi, Gustavo Rossi, Jose Saadi, Jordán Scherñuk, Pablo Slullitel, María Verona Stang, María Victoria Taboada, Sebastian Tirapegui, Constanza Uffelmann, Carlos Vaccaro, Roberto Vagni, Ana Clara Valerio, Celeste Soledad Zarratea, Carina Chwat, Silvina Montal, Brian Morris, Pedro Valdez, Fernando Diaz-Couselo,Ricci C, Casadei R, Fruscio, R, Ornaghi, S, Felice Pecoraro, Emanuele Cammarata, Sofia Campanella, Daniela Canzonieri, Adriana Cordova, Federico De Michele, Ettore Dinoto, Mara Franza, Leo Licari, Daniele Matta, Domenico Mirabella, Roberto Pirrello, Pierfrancesco Pugliese, Fernando Rosatti, Giuseppe Salamone, Francesca Toia, Massimiliano Tripoli, Vito Chiantera, Mariano Catello Di Donna, Collaborative, Covidsurg, Collaborative, Globalsurg, Palmisano, Silvia, de Manzini, Nicolo', Simoes, J, Rosati, R, on behalf of COVIDSurg Collaborative, GlobalSurg Collaborative, Aldrighetti, L, Mortini, P, Olmi, S, Medical Oncology, Assoc Surg Training ASiT, European Soc Coloproctology ESCP, EuroSurg, G4 Alliance, GlobalPaedSurg, GICS, ItSURG, ISRC, Italian Soc Colorectal Surg SICCR, PTSurg, S-ECCO, South African Soc, and SpainSurg
Subjects: Lung Diseases, Male, Internationality, SARS-Cov-2, COVID-19, surgery, pathways, pre-operative isolation, Settore MED/18 - CHIRURGIA GENERALE, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Lung Disease, ESTUDOS PROSPECTIVOS, Cohort Studies, Patient Isolation, Postoperative Complications, 80 and over, Prospective Studies, Prospective cohort study, 610 Medicine & health, Aged, 80 and over, Incidence (epidemiology), Treatment Outcome, Elective Surgical Procedures, Female, Elective Surgical Procedure, Cohort study, Human, medicine.medical_specialty, Isolation (health care), Preoperative care, NO, Anesthesiology, Preoperative Care, medicine, Humans, Elective surgery, LS7_4, Aged, business.industry, pathway, Surgery, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Prospective Studie, Anesthesiology and Pain Medicine, Human medicine, Postoperative Complication, Cohort Studie, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p=0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3days, with an OR (95%CI) at 4–7days or ≥8days of 1.25 (1.04–1.48), p=0.015 and 1.31 (1.11–1.55), p=0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care. We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p=0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3days, with an OR (95%CI) at 4–7days or ≥8days of 1.25 (1.04–1.48), p=0.015 and 1.31 (1.11–1.55), p=0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care.
Published: 2021

15. Glycogen storage disease type VI: clinical course and molecular background

Author: Gabriella Allegri, Peter K. Bode, Tim R J Aeppli, Daisy Rymen, Johannes Häberle, University of Zurich, and Aeppli, Tim R J
Subjects: Male, medicine.medical_specialty, Glycogen storage disease type VI, Mutation, Missense, 610 Medicine & health, Disease, Hypoglycemia, Gastroenterology, Glycogen Phosphorylase, Liver Form, 03 medical and health sciences, chemistry.chemical_compound, Glycogen phosphorylase, 0302 clinical medicine, 10049 Institute of Pathology and Molecular Pathology, 030225 pediatrics, Molecular genetics, Internal medicine, medicine, Humans, 2735 Pediatrics, Perinatology and Child Health, 030212 general & internal medicine, Glycogen Storage Disease Type VI, Retrospective Studies, Hypertriglyceridemia, Glycogen, business.industry, Metabolic disorder, Infant, nutritional and metabolic diseases, Starch, medicine.disease, chemistry, 10036 Medical Clinic, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, business
Abstract: Glycogen storage disease type VI (GSD-VI; also known as Hers disease, liver phosphorylase deficiency) is caused by mutations in the gene coding for glycogen phosphorylase (PYGL) leading to a defect in the degradation of glycogen. Since there are only about 40 patients described in literature, our knowledge about the course of the disease is limited. In order to evaluate the long-term outcome of patients with GSD-VI, an observational retrospective case study of six patients was performed at the University Children's Hospital Zurich. The introduction of small, frequent meals as well as cornstarch has led to normal growth in all patients and to normalization of liver transaminases in most patients. After starting the dietary regimen, there were no signs of hypoglycemia. However, three of six patients showed persistent elevation of triglycerides. Further, we identified four novel pathogenic PYGL mutations and describe here their highly variable impact on phosphorylase function.Conclusions: After establishing the diagnosis, dietary treatment led to metabolic stability and to prevention of hypoglycemia. Molecular genetics added important information for the understanding of the clinical variability in this disease. While outcome was overall excellent in all patients, half of the patients showed persistent hypertriglyceridemia even after initiating treatment.What is Known:• Glycogen storage disease type VI (GSD-VI) is a metabolic disorder causing a defect in glycogen degradation. Dietary treatment normally leads to metabolic stability and prevention of hypoglycemia.• However, our knowledge about the natural course of patients with GSD-VI is limited.What is New:• While outcome was overall excellent in all patients, half of the patients showed persistent hypertriglyceridemia even after initiating treatment.• Molecular genetics added important information for the understanding of the clinical variability in this disease.
Published: 2019

16. Effect of Pregnancy and Concomitant Antiretrovirals on the Pharmacokinetics of Tenofovir in Women With HIV Receiving Tenofovir Disoproxil Fumarate‐Based Antiretroviral Therapy Versus Women With HBV Receiving Tenofovir Disoproxil Fumarate Monotherapy

Author: Angela Colbers, David M. Burger, Elise J. Smolders, Tim R. Cressey, Gonzague Jourdain, Vera E. Bukkems, Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), and Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])
Subjects: Human immunodeficiency virus (HIV), HIV Infections, medicine.disease_cause, 030226 pharmacology & pharmacy, Gastroenterology, 0302 clinical medicine, Drug Interactions, hepatitis, Pharmacology (medical), Pregnancy Complications, Infectious, Randomized Controlled Trials as Topic, Reverse-transcriptase inhibitor, Postpartum Period, virus diseases, Hepatitis B, 3. Good health, Area Under Curve, 030220 oncology & carcinogenesis, Reverse Transcriptase Inhibitors, Female, pregnancy, medicine.drug, Adult, medicine.medical_specialty, Anti-HIV Agents, antiretroviral therapy, Young Adult, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Pharmacokinetics, Internal medicine, medicine, Humans, Protease inhibitor (pharmacology), Tenofovir, Retrospective Studies, Pharmacology, Hepatitis B virus, Pregnancy, business.industry, HIV, medicine.disease, Antiretroviral therapy, Infectious Disease Transmission, Vertical, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Concomitant, Women's Health, tenofovir disoproxil fumarate, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: International audience; Tenofovir disoproxil fumarate (TDF) is recommended as part of antiretroviral therapy (ART) for pregnant women with HIV and as monotherapy for pregnant women with hepatitis B virus (HBV) monoinfection at high risk of transmitting infection to their infants. Tenofovir (TFV) plasma exposures are reduced during pregnancy; however, concomitant antiretrovirals and the viral infection itself can also influence TFV pharmacokinetics. Our aim was to compare TFV pharmacokinetics in pregnant women receiving TDF-based ART, with or without a ritonavir-boosted protease inhibitor (r/PI), to pregnant women with HBV receiving TDF monotherapy. Non-r/PI regimens were primarily integrase strand transfer inhibitors or nonnucleoside reverse transcriptase inhibitor-based regimens. Data were combined from a pharmacokinetic study of pregnant women with HIV on ART (PANNA), and a study assessing TFV pharmacokinetics in pregnant women with HBV (iTAP). A total of 196 pregnant women, 59 with HIV (32 receiving r/PIs) and 137 with HBV monoinfection were included. Intraindividual TFV area under the plasma concentration-time curve from time 0 to 24 hours was 25%, 26%, and 21% lower during the third trimester compared to 1 month postpartum in women with HIV using TDF and an r/PI or TDF and non-r/PI and women with HBV receiving TDF monotherapy, respectively. TFV area under the plasma concentration-time curve from time 0 to 24 hours was similar in pregnant women receiving non-r/PI to pregnant women with HBV receiving TDF monotherapy (1.84 vs 1.86 µg • h/mL); however, pregnant women receiving TDF with an r/PI had higher exposures (2.41 µg • h/mL; P < .01). Pregnancy reduces TFV exposure and the relative size was not impacted by concomitant antiretroviral drugs or viral infection, but a drug-drug interaction between TDF and r/PI remains during pregnancy, leading to higher exposures than those on TDF and non-r/PI or TDF monotherapy.
Published: 2020

17. Emulating Human Tissues and Organs: A Bioprinting Perspective Toward Personalized Medicine

Author: Marco Domingos, Samuel R. Moxon, Susan J. Kimber, Miguel J. S. Ferreira, Tim R. Dargaville, Ferry P.W. Melchels, Geoffrey Potjewyd, and Ana C. Fonseca
Subjects: Spatial positioning, Structural organization, Tissue Engineering, Tissue Scaffolds, 010405 organic chemistry, Chemistry, business.industry, Polymers, Bioprinting, General Chemistry, Human physiology, Review, 010402 general chemistry, 01 natural sciences, Regenerative medicine, 0104 chemical sciences, 3. Good health, Tissue engineering, Printing, Three-Dimensional, Humans, Biochemical engineering, Personalized medicine, Precision Medicine, business, Induced pluripotent stem cell
Abstract: The lack of in vitro tissue and organ models capable of mimicking human physiology severely hinders the development and clinical translation of therapies and drugs with higher in vivo efficacy. Bioprinting allow us to fill this gap and generate 3D tissue analogues with complex functional and structural organization through the precise spatial positioning of multiple materials and cells. In this review, we report the latest developments in terms of bioprinting technologies for the manufacturing of cellular constructs with particular emphasis on material extrusion, jetting, and vat photopolymerization. We then describe the different base polymers employed in the formulation of bioinks for bioprinting and examine the strategies used to tailor their properties according to both processability and tissue maturation requirements. By relating function to organization in human development, we examine the potential of pluripotent stem cells in the context of bioprinting toward a new generation of tissue models for personalized medicine. We also highlight the most relevant attempts to engineer artificial models for the study of human organogenesis, disease, and drug screening. Finally, we discuss the most pressing challenges, opportunities, and future prospects in the field of bioprinting for tissue engineering (TE) and regenerative medicine (RM).
Published: 2020

18. Current understanding of fibrosis in genetic cardiomyopathies

Author: Rudolf A. de Boer, Tim R Eijgenraam, and Herman H W Silljé
Subjects: medicine.medical_specialty, MYOCARDIAL FIBROSIS, Cardiomyopathy, Diastole, Heart failure, Disease, MUTATION CARRIERS, 030204 cardiovascular system & hematology, DIAGNOSIS, DISEASE, Imaging, 03 medical and health sciences, VENTRICULAR NON-COMPACTION, 0302 clinical medicine, Fibrosis, Internal medicine, medicine, Genetics, Animals, Humans, Genetic Predisposition to Disease, 030212 general & internal medicine, Pathological, Ventricular Remodeling, CARDIAC MAGNETIC-RESONANCE, HYPERTROPHIC CARDIOMYOPATHY, business.industry, Myocardium, LATE GADOLINIUM ENHANCEMENT, Hypertrophic cardiomyopathy, Genetic Variation, medicine.disease, Remodeling, 3. Good health, Phenotype, Cardiology, Myocardial fibrosis, Cardiology and Cardiovascular Medicine, business, Cardiomyopathies, INTERSTITIAL FIBROSIS, TASK-FORCE
Abstract: Myocardial fibrosis is the excessive deposition of extracellular matrix proteins, including collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or replacement fibrosis is almost always part of the pathological cardiac remodeling process. Different forms of cardiomyopathies show particular patterns of myocardial fibrosis that can be considered as distinctive hallmarks. Although formation of fibrosis is initially aimed to be a reparative mechanism, in the long term, on-going and excessive myocardial fibrosis may lead to arrhythmias and stiffening of the heart wall and subsequently to diastolic dysfunction. Ultimately, adverse remodeling with progressive myocardial fibrosis can lead to heart failure. Not surprisingly, the presence of fibrosis in cardiomyopathies, even when subtle, has consistently been associated with complications and adverse outcomes. In the last decade, non-invasive in vivo techniques for visualization of myocardial fibrosis have emerged, and have been increasingly used in research and in the clinic. In this review, we will describe the epidemiology, distribution, and role of myocardial fibrosis in genetic cardiomyopathies, including hypertrophic, dilated, arrhythmogenic, and non-compaction cardiomyopathy, and a few specific forms of genetic cardiomyopathies.
Published: 2020

19. Point-of-care and Near Real-time Testing for Antiretroviral Adherence Monitoring to HIV Treatment and Prevention

Author: Connie Celum, Pete Anderson, Monica Gandhi, Ashley Bardon, Ayokunle Olanrewaju, Derin Sevenler, Jane M. Simoni, Paul K. Drain, and Tim R. Cressey
Subjects: Counseling, 0301 basic medicine, medicine.medical_specialty, Anti-HIV Agents, Point-of-Care Systems, Point-of-care testing, Real-time computing, Psychological intervention, Human immunodeficiency virus (HIV), HIV Infections, medicine.disease_cause, Article, Medication Adherence, 03 medical and health sciences, 0302 clinical medicine, Virology, Humans, Medicine, 030212 general & internal medicine, Hiv treatment, Tenofovir, Point of care, business.industry, Public health, 030104 developmental biology, Infectious Diseases, Adherence monitoring, Female, Pre-Exposure Prophylaxis, Public Health, business, Aids pandemic
Abstract: PURPOSE OF REVIEW: In this report, we review the need for point-of-care (POC) or near real-time testing for antiretrovirals, progress in the field, evidence for guiding implementation of these tests globally, and future directions in objective antiretroviral therapy (ART) or pre-exposure prophylaxis (PrEP) adherence monitoring. RECENT FINDINGS: Two cornerstones to end the HIV/AIDS pandemic are ART, which provides individual clinical benefits and eliminates forward transmission, and PrEP, which prevents HIV acquisition with high effectiveness. Maximizing the individual and public health benefits of these powerful biomedical tools requires high and sustained antiretroviral adherence. Routine monitoring of medication adherence in individuals receiving ART and PrEP may be an important component in interpreting outcomes and supporting optimal adherence. Existing practices and subjective metrics for adherence monitoring are often inaccurate or unreliable, and therefore, are generally ineffective for improving adherence. Laboratory measures of antiretroviral concentrations using liquid chromatography tandem mass spectrometry have been utilized in research settings to assess medication adherence, although these are too costly and resource-intensive for routine use. SUMMARY: Newer, less costly technologies such as antibody-based methods can provide objective drug level measurement and may allow for POC or near-patient adherence monitoring in clinical settings. When coupled with timely and targeted counseling, POC drug level measures can support adherence clinic-based interventions to ART or PrEP in near real-time.
Published: 2020

20. Chirurgische Therapie der primär sklerosierenden Cholangitis

Author: Alexander Semaan, Vittorio Branchi, Jörg C. Kalff, Jonas Henn, Hanno Matthaei, Maria A. Gonzalez-Carmona, Tobias J. Weismüller, Steffen Manekeller, Taotao Zhou, Tim R. Glowka, and Christian P. Strassburg
Subjects: Gynecology, medicine.medical_specialty, business.industry, medicine.disease, Primary sclerosing cholangitis, 03 medical and health sciences, 0302 clinical medicine, Transplant surgery, Cholangiocellular carcinoma, Cardiothoracic surgery, 030220 oncology & carcinogenesis, Medicine, 030211 gastroenterology & hepatology, Surgery, business
Abstract: Zusammenfassung Hintergrund Wenngleich in Bezug auf Therapie und Krankheitsverständnis bei der primär sklerosierenden Cholangitis (PSC) in den vergangenen Jahren erhebliche Fortschritte zu beobachten sind, so ist bei Karzinom und „end-stage liver disease“ (ELD) eine Lebertransplantation (LTX) meist die einzige Chance auf Heilung. In seltenen Fällen ist eine Leberteilresektion (LR) zur kurativen Therapie des PSC-assoziierten Gallengangskarzinoms (CCC) möglich. Diese Operationen stellen für PSC-Patienten eine zusätzliche Belastung dar. Ziel Auch aufgrund der Seltenheit der Erkrankung sind detaillierte Studien zur hepatopankreatikobiliären (HPB-)Chirurgie der PSC rar. Ziel dieser Arbeit ist es, die HPB-chirurgische Indikation und Prognose von PSC Patienten zu untersuchen. Patienten und Methoden Es erfolgte eine monozentrische, retrospektive Kohortenstudie von 1990 bis 2020. In dieser wurden Patienten mit PSC eingeschlossen und in Bezug auf operationsassoziierte Faktoren sowie deren Prognose untersucht. Ergebnisse Bei 62 Patienten (36 %) war eine PSC-bedingte, größere hepatopankreatikobiliäre Operation oder Exploration notwendig. Diese Patienten litten signifikant häufiger an einer chronisch entzündlichen Darmerkrankung (p p Diskussion Ein großer Anteil der Patienten mit PSC muss aufgrund der Erkrankung operiert werden mit erheblichem Risiko für Morbidität und Mortalität. Bei fehlenden kurativen Therapieoptionen wären Frühdiagnosestrategien zu begrüßen, um das PSC-CCC im Frühstadium erkennen und behandeln zu können.
Published: 2020

21. NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

Author: Cedric Szyndralewiez, Pandurangan Vijayanand, Oliver Wood, Maria Machado, Maria-Antoinette Lopez, Chuan Wang, Emma King, Gareth J. Thomas, Natalia Savelyeva, Massimiliano Mellone, Anusha-Preethi Ganesan, Tim R. Fenton, Christopher J. Hanley, Kirsty Ford, Philippe Wiesel, Ankur Chakravarthy, Aymen Al-Shamkhani, Freddy Heitz, and Christian H. Ottensmeier
Subjects: 0301 basic medicine, Cancer Research, medicine.medical_treatment, CD8-Positive T-Lymphocytes, DNA vaccination, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Cancer-Associated Fibroblasts, Downregulation and upregulation, Cell Line, Tumor, Neoplasms, Animals, Humans, Medicine, Cytotoxic T cell, biology, business.industry, Immunotherapy, 030104 developmental biology, Oncology, NADPH Oxidase 4, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Antibody, Reactive Oxygen Species, business, CD8
Abstract: Determining mechanisms of resistance to αPD-1/PD-L1 immune-checkpoint immunotherapy is key to developing new treatment strategies. Cancer-associated fibroblasts (CAF) have many tumor-promoting functions and promote immune evasion through multiple mechanisms, but as yet, no CAF-specific inhibitors are clinically available. Here we generated CAF-rich murine tumor models (TC1, MC38, and 4T1) to investigate how CAFs influence the immune microenvironment and affect response to different immunotherapy modalities [anticancer vaccination, TC1 (HPV E7 DNA vaccine), αPD-1, and MC38] and found that CAFs broadly suppressed response by specifically excluding CD8+ T cells from tumors (not CD4+ T cells or macrophages); CD8+ T-cell exclusion was similarly present in CAF-rich human tumors. RNA sequencing of CD8+ T cells from CAF-rich murine tumors and immunochemistry analysis of human tumors identified significant upregulation of CTLA-4 in the absence of other exhaustion markers; inhibiting CTLA-4 with a nondepleting antibody overcame the CD8+ T-cell exclusion effect without affecting Tregs. We then examined the potential for CAF targeting, focusing on the ROS-producing enzyme NOX4, which is upregulated by CAF in many human cancers, and compared this with TGFβ1 inhibition, a key regulator of the CAF phenotype. siRNA knockdown or pharmacologic inhibition [GKT137831 (Setanaxib)] of NOX4 “normalized” CAF to a quiescent phenotype and promoted intratumoral CD8+ T-cell infiltration, overcoming the exclusion effect; TGFβ1 inhibition could prevent, but not reverse, CAF differentiation. Finally, NOX4 inhibition restored immunotherapy response in CAF-rich tumors. These findings demonstrate that CAF-mediated immunotherapy resistance can be effectively overcome through NOX4 inhibition and could improve outcome in a broad range of cancers. Significance: NOX4 is critical for maintaining the immune-suppressive CAF phenotype in tumors. Pharmacologic inhibition of NOX4 potentiates immunotherapy by overcoming CAF-mediated CD8+ T-cell exclusion.
Published: 2020

22. Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial

Author: Kulkanya Chokephaibulkit, George K. Siberry, Tim R. Cressey, Patricia Anthony, Blandina T. Mmbaga, R Leavitt Morrison, Mark Mirochnick, Peerawong Werarak, Lisa M. Frenkel, Trevon Fuller, Maria Isabel Fragoso da Silveira Gouvêa, Brookie M. Best, Nahida Chakhtoura, Maria de Lourdes Benamor Teixeira, Luis Felipe Moreira, María José Rolón, José Henrique Pilotto, Esau Joao, Sinart Prommas, Lauren Laimon, James S. Ngocho, Zaakirah Essack, Boniface N. Njau, Roslyn Hennessy, Ruth Mathiba, David Shapiro, Pedro Cahn, and Avy Violari
Subjects: Cyclopropanes, Outcome Assessment, Epidemiology, Infectious Disease Transmission, Integrase inhibitor, HIV Infections, Reproductive health and childbirth, Medical and Health Sciences, law.invention, chemistry.chemical_compound, Randomized controlled trial, Pregnancy, law, Outcome Assessment, Health Care, Vertical, Pregnancy Complications, Infectious, Pediatric, Infectious, virus diseases, Viral Load, Mental Health, Infectious Diseases, Anti-Retroviral Agents, Lamivudine, 6.1 Pharmaceuticals, Alkynes, Combination, Dolutegravir, HIV/AIDS, Drug Therapy, Combination, Female, Infection, Zidovudine, Viral load, medicine.drug, Adult, medicine.medical_specialty, Efavirenz, Anti-HIV Agents, Clinical Trials and Supportive Activities, Immunology, Article, Young Adult, Drug Therapy, Clinical Research, Raltegravir Potassium, Virology, Internal medicine, parasitic diseases, medicine, Humans, HIV Integrase Inhibitors, business.industry, Prevention, Infant, Newborn, Infant, Evaluation of treatments and therapeutic interventions, National Institute of Child Health and Human Development (U.S.), Newborn, Raltegravir, Infectious Disease Transmission, Vertical, United States, Benzoxazines, Pregnancy Complications, Health Care, Clinical trial, Regimen, Good Health and Well Being, chemistry, business
Abstract: BackgroundAlthough antiretroviral regimens containing integrase inhibitors rapidly suppress HIV viral load in non-pregnant adults, few published data from randomised controlled trials have compared the safety and efficacy of any integrase inhibitor to efavirenz when initiated during pregnancy. We compared safety and efficacy of antiretroviral therapy with either raltegravir or efavirenz in late pregnancy.MethodsAn open-label, randomised controlled trial was done at 19 hospitals and clinics in Argentina, Brazil, South Africa, Tanzania, Thailand, and the USA. Antiretroviral-naive pregnant women (20
Published: 2020

23. Prevalence of Mycoplasma genitalium by anatomical site in men who have sex with men: a systematic review and meta-analysis

Author: Rosie L. Latimer, Hannah Shilling, Eric P F Chow, Christopher K Fairley, Lenka A. Vodstrcil, Catriona S. Bradshaw, Tim R H Read, and Dorothy A Machalek
Subjects: medicine.medical_specialty, Chlamydia, biology, business.industry, Pharynx, Rectum, Dermatology, medicine.disease, biology.organism_classification, Asymptomatic, Men who have sex with men, Infectious Diseases, medicine.anatomical_structure, Urethra, Meta-analysis, Internal medicine, Medicine, medicine.symptom, business, Mycoplasma genitalium
Abstract: ObjectiveTo systematically review and appraise published data, to determine the prevalence of Mycoplasma genitalium (MG) in men who have sex with men (MSM) tested at each anatomical site, that is, at the urethra, rectum and/or pharynx.DesignSystematic review and meta-analysis.Data sourcesOvid Medline, PubMed, Embase were searched for articles from 1st January 1981 (the year MG was first identified) to 1st June 2018.Review methodsStudies were eligible for inclusion if they reported MG prevalence in MSM tested at the urethra, rectum and/or pharynx, in at least 50 MSM, using nucleic acid amplification testing. Data were extracted by anatomical site, symptom and HIV status. Summary estimates (95% CIs) were calculated using random-effects meta-analysis. Subgroup analyses were performed to assess heterogeneity between studies.ResultsForty-six studies met inclusion criteria, with 34 reporting estimates of MG prevalence at the urethra (13 753 samples), 25 at the rectum (8629 samples) and 7 at the pharynx (1871 samples). MG prevalence was 5.0% (95% CI 3.5 to 6.8; I2=94.0) at the urethra; 6.2% (95% CI 4.6 to 8.1; I2=88.1) at the rectum and 1.0% (95% CI 0.0 to 5.1; I2=96.0) at the pharynx. The prevalence of MG was significantly higher at urethral and rectal sites in symptomatic versus asymptomatic MSM (7.1% vs 2.2%, pConclusionMG was common in MSM, particularly at urethral and rectal sites (5% to 6%). MG was more commonly detected in symptomatic men at both sites, and more common in HIV-positive men at the urethra. MG was uncommonly detected in the pharynx. Site-specific estimates are similar to those for chlamydia and will be helpful in informing testing practices in MSM.PROSPERO registration numberCRD42017058326.
Published: 2020

24. Heterogeneity in Auction Price Distributions for Australian Indigenous Artists

Author: Tim R. L. Fry
Subjects: TheoryofComputation_MISCELLANEOUS, Economics and Econometrics, Conditional moments, Financial economics, business.industry, 05 social sciences, TheoryofComputation_GENERAL, Distribution (economics), GeneralLiterature_MISCELLANEOUS, Indigenous, 0502 economics and business, Economics, 050207 economics, business, Period (music), 050205 econometrics
Abstract: Studies of auction prices for artworks typically relate the conditional moments of a single realised price distribution either to characteristics of the artist, the artwork and the auction or to pre‐sale information. Using data from the Australian Art Sales Digest for the 100 best‐selling Australian Indigenous artists over the period 1987–2014, we use finite‐mixture models to understand heterogeneity in auction prices. Our results complement the existing literature by identifying new ways in which factors previously used in the literature may be related to price heterogeneity in a differentiated market such as that for Australian Indigenous art. [ABSTRACT FROM AUTHOR]
Published: 2020

25. HPV-associated anal lesions in HIV+ patients: long-term results regarding quality of life

Author: Christoph Boesecke, Carolynne Schwarze-Zander, Martin W. von Websky, Paul C. Wesselmann, Tim O. Vilz, Tim R. Glowka, Jörg C. Kalff, B Stoffels, and Jürgen K. Rockstroh
Subjects: Quality of life, Adult, Male, medicine.medical_specialty, HPV, Time Factors, SF-36, Adolescent, Sexual Behavior, Human immunodeficiency virus (HIV), Condyloma, medicine.disease_cause, Anal intraepithelial neoplasia, Anal lesions, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Recurrence, Internal medicine, Surveys and Questionnaires, HIV Seropositivity, medicine, Humans, 030212 general & internal medicine, business.industry, Gastroenterology, HIV, Anal dysplasia, Hepatology, Middle Aged, medicine.disease, Anus Neoplasms, Condylomata Acuminata, Concomitant, Hiv patients, 030211 gastroenterology & hepatology, Original Article, Neoplasm Recurrence, Local, business, Carcinoma in Situ, Stress, Psychological, Follow-Up Studies
Abstract: Purpose HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients’ quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality. Material and methods Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approach after undergoing routine proctologic assessment and therapy for HPV-associated anal lesions if indicated over a time span of 11 years (11/2004–11/2015). Therapy consisted of surgical ablation and topic treatment. QoL was analyzed using the SF-36 and the CECA questionnaires. Results Fifty-two of 67 patients (77.6%) were successfully contacted and 29/52 provided full information. The mean age was 43.8 ± 12.8 years. The median follow-up from treatment to answering of the questionnaire was 34 months. Twenty-one percent (6/29) of the patients reported suffering from recurrence of condyloma acuminata, three patients from anal dysplasia (10.3%). In the SF-36, HIV+ patients did not rate their QoL as significantly different over all items after successful treatment of HPV-associated anal lesions. In the CECA questionnaire, patients with persisting HPV-associated anal lesions reported significantly higher emotional stress levels and disturbance of everyday life compared to patients who had successful treatment (71.9/100 ± 18.7 vs. 40.00/100 ± 27.4, p = 0.004). Importantly, the sexuality of patients with anal lesions was significantly impaired (59.8/100 ± 30.8 vs. 27.5/100 ± 12.2, p = 0.032). Conclusion HPV-associated anal lesions impact significantly negative on QoL in HIV+ patients. Successful treatment of HPV-associated anal lesions in HIV+ patients improved QoL. Specific questionnaires, such as CECA, seem to be more adequate than the SF-36 in this setting.
Published: 2020

26. Development and validation of the first point-of-care assay to objectively monitor adherence to HIV treatment and prevention in real-time in routine settings

Author: Guohong Wang, Oraphan Siriprakaisil, Tim R. Cressey, Peter Bacchetti, Roger King, Jared M Baeten, Paul K Drain, David V. Glidden, Monica Gandhi, Michael Vincent, Matthew A Spinelli, Nelly Mugo, Warren C. Rodrigues, Kenneth Ngure, Hideaki Okochi, and Virat Klinbuayaem
Subjects: antiretroviral treatment, 0301 basic medicine, preexposure prophylaxis, Human immunodeficiency virus (HIV), Metal Nanoparticles, HIV Infections, medicine.disease_cause, Medical and Health Sciences, 0302 clinical medicine, Tandem Mass Spectrometry, Immunology and Allergy, Medicine, adherence, 030212 general & internal medicine, Hiv treatment, Chromatography, Liquid, Biological Sciences, urine, Infectious Diseases, Point-of-Care Testing, Treatment study, HIV/AIDS, Infection, medicine.medical_specialty, Anti-HIV Agents, Clinical Trials and Supportive Activities, Immunology, MEDLINE, Bioengineering, Article, Medication Adherence, 03 medical and health sciences, Clinical Research, Virology, Humans, Tenofovir, Intensive care medicine, Point of care, business.industry, Extramural, Prevention, Psychology and Cognitive Sciences, lateral flow assay, Good Health and Well Being, 030104 developmental biology, point-of-care, Pre-Exposure Prophylaxis, Gold, business, Chromatography, Liquid
Abstract: OBJECTIVE: HIV prevention and treatment studies demonstrate that pharmacologic adherence metrics are more accurate than self-report. Currently-available metrics use liquid-chromatography/tandem-mass-spectrometry (LC-MS/MS), which is expensive and laboratory-based. We developed a specific and sensitive antibody against tenofovir, the backbone of treatment and prevention, but conversion to a lateral flow assay (LFA) –analogous to a urine pregnancy test- is required for point-of-care testing. We describe the development of the first LFA to measure antiretroviral adherence in real-time. METHODS: Previous work in a directly-observed therapy study of providing tenofovir-disoproxil fumarate (TDF) to HIV-noninfected volunteers at various simulated adherence patterns defined the appropriate cut-off for the LFA (1500ng tenofovir/ml urine). We developed the LFA using a sample pad for urine; a conjugate pad coated with TFV-specific antibodies conjugated to colloidal gold nanoparticles; a nitrocellulose membrane striped with tenofovir-antigen (test line) and a control line; with an absorbent pad to draw urine across the reaction membrane. RESULTS: We tested 300 urine samples collected from the directly-observed therapy study by this LFA and the gold-standard method of LC-MS/MS. The LFA demonstrated 97% specificity (95% CI: 93% to 99%) and 99% sensitivity (94% to 100%) compared to LC-MS/MS. The LFA accurately classified 98% of patients who took a dose within 24 hours as adherent. CONCLUSION: We describe the development and validation of the first point-of-care assay to measure short-term adherence to HIV prevention and treatment in routine settings. The assay is low-cost, easy-to-perform and measures the breakdown product (tenofovir) of both TDF and tenofovir alafenamide (TAF). This assay has the potential to improve HIV and PrEP outcomes worldwide by triggering differentiated service delivery with further study merited.
Published: 2020

27. Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits

Author: Catriona S. Bradshaw, Suzanne M. Garland, Dorothy A Machalek, Jenny Su, Deborah A Williamson, Tim R H Read, Vesna De Petra, Gerald L. Murray, Joshua Birnie, Rachel Wee, Lit Yeen Tan, and Jennifer Danielewski
Subjects: 0301 basic medicine, Microbiology (medical), Standard sample, biology, business.industry, 030106 microbiology, Diagnostic test, General Medicine, Urine, Roche Diagnostics, biology.organism_classification, Microbiology, Confidence interval, 03 medical and health sciences, 030104 developmental biology, Specimen collection, Macrolide resistance, Medicine, Nuclear medicine, business, Mycoplasma genitalium
Abstract: Introduction. Mycoplasma genitalium is a sexually transmitted organism with high levels of resistance to the recommended first-line therapy, azithromycin. The ResistancePlus MG test concurrently detects M. genitalium, and the presence of macrolide-resistance mutations (MRM). European, UK and Australian guidelines recommend a diagnostic test that reports MRM to optimize treatment through resistance-guided therapy. Hence, for samples collected for use on other platforms, reflex testing using the ResistancePlus MG test would be beneficial.Aim. To validate the ResistancePlus MG assay using samples collected in Aptima buffer for testing on the Hologic Panther.Methodology. Positive (n=99) and negative (n=229) clinical samples collected in Aptima buffer were extracted on the MagNA Pure 96 (Roche Diagnostics), and tested with the ResistancePlus MG test on the LightCycler 480 II (Roche Diagnostics). Results were compared to matched samples collected using standard sample collection (urine or swab resuspended in PBS), with positive percent agreement (PPA), negative percent agreement (NPA) and Cohen's Kappa statistic.Results. The ResistancePlus MG test had high performance with a 200 µl input volume (PPA/NPA for M. genitalium detection, 92.9 % [95 % confidence interval (CI): 85.5-96.9]/100 % [95 % CI: 97.9-100], MRM detection, 96.9 % [95 % CI: 88.2-99.5]/85.7 % [95 % CI: 66.4-95.3]) and for 1 ml input volume (PPA/NPA for M. genitalium detection, 95.9%/96.6%, MRM detection, 98.4%/90.3%). Samples remained positive after storage at room temperature beyond the manufacturer-recommended storage of
Published: 2020

28. Roboterassistierte Operationen in der Viszeralchirurgie

Author: M.W. von Websky, Jörg C. Kalff, Tim R. Glowka, Tim O. Vilz, and B Stoffels
Subjects: Gynecology, Visceral surgery, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, Transplant surgery, business.industry, 030220 oncology & carcinogenesis, medicine, 030211 gastroenterology & hepatology, Surgery, business
Abstract: Zwar wird aktuell nur ein Bruchteil der abdominalchirurgischen Eingriffe robotisch-assistiert durchgefuhrt, die Gesamtanzahl ist jedoch in den letzten Jahren deutlich steigend und robotisches Operieren (RO) keinesfalls mehr nur auf Universitatskliniken begrenzt. Trotz der zunehmenden Verbreitung und vieler Innovationen im Bereich der robotischen Chirurgie mit neuen Plattformen ist die Datenlage unubersichtlich. Die Ubersichtsarbeit beschaftigt sich mit den aktuellen Einsatzgebieten robotischer Plattformen in der Abdominalchirurgie und der Fragestellung, inwieweit Vorteile gegenuber der laparoskopischen Chirurgie (LO) bestehen. Es erfolgte eine Auswertung und kritische Diskussion der internationalen Literatur. Wahrend als Nachteile hohe Kosten und langere Operationszeiten aufgefuhrt werden, werden als Vorteile u. a. die stabile optische Plattform sowie die hohe Beweglichkeit selbst auf engstem Raum genannt. Jedoch gibt es bis zum jetzigen Zeitpunkt keine qualitativ hochwertige, randomisiert-kontrollierte Studie in der Abdominalchirurgie, die einen Vorteil des RO verglichen mit dem LO nachweisen konnte. Auch wenn hinsichtlich des RO fur den Patienten bislang kein eindeutiger Vorteil nachgewiesen werden konnte, so scheint es zumindest gleichwertig zum LO zu sein. Unbestritten ist der hohere Komfort fur den Operateur. Sobald die Kosten fur das RO deutlich gesenkt werden, wird das LO vermutlich in den meisten Indikationen verdrangt werden.
Published: 2020

29. Nuclear imaging for diagnosing fracture-related infection

Author: Geertje A M Govaert, Frank F A IJpma, P. Bosch, Andor W. J. M. Glaudemans, Jean-Paul P.M. de Vries, Tim R. Middelberg, Translational Immunology Groningen (TRIGR), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), and Robotics and image-guided minimally-invasive surgery (ROBOTICS)
Subjects: medicine.medical_specialty, Nuclear imaging, Diagnostic accuracy, Scintigraphy, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, BONES, OSTEOMYELITIS, Medicine, Radiology, Nuclear Medicine and imaging, In patient, FIXATION, Surgical treatment, FDG-PET, 030222 orthopedics, Fracture-related infection, medicine.diagnostic_test, business.industry, Retrospective cohort study, FRI, Fracture, Multicenter study, Radiology, business, Complication, Infection, WBC scintigraphy, CT
Abstract: Purpose Fracture-related infection (FRI) is a complication of surgical fracture treatment and can be challenging to diagnose. Recent studies show promising results for the use of either FDG-PET/CT or WBC/anti-granulocyte scintigraphy. The purpose of this pictorial essay is to outline recent developments in nuclear imaging techniques to diagnose FRI. Methods The current literature on this topic is reviewed. Additionally, three examples of patients who underwent nuclear imaging as part of their clinical work-up and surgical treatment for FRI are presented. Results Based on recent retrospective studies, FDG-PET/CT (accuracy 0.83) and WBC scintigraphy with SPECT/CT (accuracy 0.92) both have a good diagnostic accuracy for diagnosing fracture-related infection. Nuclear imaging contributes to a correct diagnosis in patients with FRI. Conclusion Retrospective studies show promising results for both FDG-PET/CT and WBC scintigraphy with SPECT/CT in diagnosing FRI. A prospective, multicenter study (IFI trial), directly comparing MRI, FDG-PET/CT, and WBC scintigraphy with SPECT/CT in patients with suspected FRI, is currently in progress.
Published: 2020

30. Surgical treatment of symptomatic neuromas: a feasibility study using the NEUROCAP (R) bioresorbable nerve capping device

Author: Tim R Schäfer, Marietta J. O. E. Bertleff, Edwin L de Vrij, Tom J. M. van Mulken, Plastische Chirurgie (PLC), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, and MUMC+: MA Plastische Chirurgie (9)
Subjects: medicine.medical_specialty, business.industry, Amputation Stumps, MEDLINE, Surgery, Short Report Letters, Neuroma, Text mining, Absorbable Implants, Medicine, Feasibility Studies, Humans, business, Surgical treatment
Published: 2022

31. Past Antarctic ice sheet dynamics (PAIS) and implications for future sea-level change

Author: Stewart S. R. Jamieson, Michael J. Bentley, Claus-Dieter Hillenbrand, David J. Wilson, German Leitchenkov, Florence Colleoni, Laura De Santis, Tina van de Flierdt, Lara F. Pérez, Katharina Hochmuth, Francesca Sangiorgi, Paolo Stocchi, Gabriele Uenzelmann-Neben, Robert M. DeConto, Tim R Naish, and Carlota Escutia
Subjects: Sea level change, geography.geographical_feature_category, 010504 meteorology & atmospheric sciences, Research philosophy, business.industry, Global warming, Environmental resource management, Antarctic ice sheet, Future sea level, Numerical models, 010502 geochemistry & geophysics, 01 natural sciences, Geography, 13. Climate action, Dynamics (music), 14. Life underwater, Ice sheet, business, 0105 earth and related environmental sciences
Abstract: The legacy of the Scientific Committee on Antarctic Research’s (SCAR) PAIS strategic research programme includes not only breakthrough scientific discoveries, but it is also the story of a long-standing deep collaboration amongst different multi-disciplinary researchers from many nations, to share scientific infrastructure and data, facilities, and numerical models, in order to address high priority questions regarding the evolution and behaviour of the Antarctic ice sheets (AIS). The PAIS research philosophy is based on data-data and data-model integration and intercomparison, and the development of ‘ice-to-abyss’ data transects and paleo-environmental, extending from the ice sheet interior to the deep sea. PAIS strives to improve understanding of AIS dynamics and to reduce uncertainty in model simulations of future ice loss and global sea level change, by studying warm periods of the geological past that are relevant to future climate scenarios. The multi-disciplinary approach fostered by PAIS represents its greatest strength. Eight years after the start of this programme, PAIS achievements have been high-profile and impactful, both in terms of field campaigns that collected unique data sets and samples, and in terms of scientific advances concerning past AIS dynamics, that have measurably improved understanding of ice sheet sensitivity in response to global warming. Here we provide an overview and synthesis of the new knowledge generated by the PAIS Programme and its implications for anticipating and managing the impacts of global sea-level rise.
Published: 2022

32. The future evolution of Antarctic climate: conclusions and upcoming programmes

Author: Martin J. Siegert, Laura De Santis, Tim R Naish, and Fabio Florindo
Subjects: Geography, geography.geographical_feature_category, business.industry, Global warming, Environmental resource management, Antarctic climate, Vulnerability, Antarctic ice sheet, Glacial period, Ice sheet, business
Abstract: Our appreciation of Antarctic climate evolution has grown significantly in the last decade. Characterised by international cooperation, and leadership from the Scientific Committee on Antarctic Research (SCAR), we now have a better understanding of how and why Antarctica’s ice sheets have developed and influenced global climate change. While the nature of, and explanations for, significant glacial events has improved, gaps in our knowledge of the rate and impact of processes responsible remain. Such processes are critical if we are to understand how the palaeo record can inform us about the vulnerability of the Antarctic ice sheet during periods of greenhouse gas–driven warming. Hence, establishing further precision of past changes, at a resolution helpful to process-based modelling, is an important next step to better constraining future Antarctic change and its sea-level consequences.
Published: 2022

33. Attributes of climate resilience in fisheries: From theory to practice

Author: Claudio Silva, Lily Z. Zhao, Julia G. Mason, Jacob G. Eurich, Willow Battista, Christopher M. Free, Jacqueline Lau, Mark Dickey-Collas, María Á. Barbieri, Whitney R. Friedman, Mireia Valle, Kanae Tokunaga, Tim R. McClanahan, Katherine E. Mills, Gretta T. Pecl, Joshua E. Cinner, Kristin M. Kleisner, Edward H. Allison, and Eleuterio Yáñez
Subjects: Adaptive capacity, business.industry, Social-ecological systems, Environmental resource management, Theory to practice, Global change, Management, Monitoring, Policy and Law, Aquatic Science, Oceanography, Climate resilience, Synthesis science, Fisheries management, Economics, SDG 13 - Climate Action, Coastal communities, SDG 14 - Life Below Water, business, Ecology, Evolution, Behavior and Systematics
Abstract: In a changing climate, there is an imperative to build coupled social-ecological systems—including fisheries—that can withstand or adapt to climate stressors. Although resilience theory identifies system attributes that supposedly confer resilience, these attributes have rarely been clearly defined, mechanistically explained, nor tested and applied to inform fisheries governance. Here, we develop and apply a comprehensive resilience framework to examine fishery systems across (a) ecological, (b) socio-economic and (c) governance dimensions using five resilience domains: assets, flexibility, organization, learning and agency. We distil and define 38 attributes that confer climate resilience from a coupled literature- and expert-driven approach, describe how they apply to fisheries and provide illustrative examples of resilience attributes in action. Our synthesis highlights that the directionality and mechanism of these attributes depend on the specific context, capacities, and scale of the focal fishery system and associated stressors, and we find evidence of interdependencies among attributes. Overall, however, we find few studies that test resilience attributes in fisheries across all parts of the system, with most examples focussing on the ecological dimension. As such, meaningful quantification of the attributes’ contributions to resilience remains a challenge. Our synthesis and holistic framework represent a starting point for critical application of resilience concepts to fisheries social-ecological systems.
Published: 2022

34. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

Author: Nepogodiev, Dmitri, Simoes, Joana FF, Elizabeth, Li, Picciochi, Maria, Glasbey, James C, Baiocchi, Glauco, Blanco‐colino, Ruth, Chaudhry, Daoud, Alameer, Ehab, El‐boghdadly, Kariem, Wuraola, Funmilola, Ghosh, Dhruva, Gujjuri, Rohan R, Harrison, Ewen M, Lule, Herman, Kaafarani, Haytham, Khosravi, Mohammad, Kronberger, Irmgard, Leventoğlu, Sezai, Mann, Harvinder, Mclean, Kenneth A, Mengesha, Mengistu Gebreyohanes, Modolo, Maria Marta, Ntirenganya, Faustin, Norman, Lisa, Outani, Oumaima, Pius, Riinu, Pockney, Peter, Qureshi, Ahmad Uzair, Roslani, April Camilla, Satoi, Sohei, Shaw, Catherine, Bhangu, Aneel, Omar, Omar M, Ahmed, Waheed‐ul‐rahman, Argus, Leah, Ball, Alasdair, Bywater, Edward P, Brar, Amanpreet, Dawson, Brett E, Duran, Irani, Elhadi, Muhammed, Jones, Conor S, Kamarajah, Sivesh K, Keatley, James M, Lawday, Samuel, Marson, Ella J, Ots, Riinu, Santos, Irène, Taylor, Elliott H, Trout, Isobel M, Varghese, Chris, Venn, Mary L, William, Xu, Dajti, Irida, Gjata, Arben, Kacimi, Salah Eddine Oussama, Boccalatte, Luis, Cox, Daniel, Townend, Philip, Aigner, Felix, Kronberger, Irmgard Elisabeth, Samadov, Elgun, Alderazi, Amer, Hossain, Kamral, Padmore, Greg, Ramshorst, Gabrielle, Lawani, Ismaïl, Cerovac, Anis, Delibegovic, Samir, Gomes, Gustavo Mendonça Ataíde, Buarque, Igor Lima, Gohar, Muhammad, Slavchev, Mihail, Nwegbu, Chukwuemeka, Agarwal, Arnav, Martin, Janet, Ng‐kamstra, Joshua, Olivos, Maricarmen, Lou, Wenhui, Ren, Dong‐lin, Calvache, Jose Andres, Perez Rivera, Carlos J, Hadzibegovic, Ana Danic, Kopjar, Tomislav, Mihanovic, Jakov, Jiménez, Pablo Mijahil Avilés, Gouvas, Nikolaos, Klat, Jaroslav, Novysedlák, René, Amisi, Nicolas, Christensen, Peter, El‐hussuna, Alaa, Batista, Sylvia, Lincango‐naranjo, Eddy, Emile, Sameh, Sandoval, Danilo Alfonso Arévalo, Dhufera, Hailu, Hailu, Samuel, Mengesha, Mengistu G, Kauppila, Joonas H, Arnaud, Alexis P, Demetrashvili, Zaza, Albertsmeier, Markus, Lederhuber, Hans, Löffler, Markus W., Acquah, Daniel Kwesi, Ofori, Bernard, Tabiri, Stephen, Metallidis, Symeon, Tsoulfas, Georgios, Aguilera‐arevalo, Maria‐lorena, Recinos, Gustavo, Mersich, Tamás, Wettstein, Dániel, Kembuan, Gabriele, Milan, Peiman Brouki, Khosravi, Mohammad Hossein, Mozafari, Masoud, Hilmi, Ahmed, Mohan, Helen, Zmora, Oded, Gallo, Gaetano, Pata, Francesco, Pellino, Gianluca, Fujimoto, Yuki, Kuroda, Naoto, Abou Chaar, Mohamad K., Ayasra, Faris, Fakhradiyev, Ildar, Hamdun, Intisar Hisham Said, Jin‐young, Jang, Jamal, Mohammad, Karout, Lina, Gulla, Aiste, Rasoaherinomenjanahary, Fanjandrainy, Samison, Luc Hervé, Sánchez, Iran Irani Durán, Gonzalez, Diana Samantha, Martinez, Laura, Martínez, María José, Nayen, Alejandra, Medina, Antonio Ramos‐De, Nunez, Jade, Nashidengo, Pueya Rashid, Shah, Rakesh, Shrestha, Ashish Lal, Jonker, Pascal, Kruijff, Schelto, Noltes, Milou, Steinkamp, Pieter, Wright, Deborah, Abdur‐rahman, Lukman, Ademuyiwa, Adesoji, Adisa, Adewale, Osinaike, Babatunde, Seyi‐olajide, Justina, Williams, Omolara, Williams, Emmanuel, Pejkova, Sofija, Al Balushi, Zainab, Sayyed, Raza, Mohsen, Mustafa Abo, Abukhalaf, Sadi A., Cukier, Moises, Gomez‐fernandez, Hugo, Yip, Sebastian Shu, Ojeda, Ximena Paola Vasquez, Sacdalan, Marie Dione, Major, Piotr, Azevedo, José, Cunha, Miguel F., Zarour, Ahmad, Bonci, Eduard‐alexandru, Negoi, Ionut, Efetov, Sergey, Kochetkov, Viktor, Litvin, Andrey, Ingabire, Jc Allen, Bucyibaruta, Georges, Faustin, Ntirenganya, Habumuremyi, Sosthene, Imanishimwe, Alphonsine, Dieu, Haragirimana Jean, Munyaneza, Emmanuel, Ncogoza, Isaie, Ndong, Abdourahmane, Radenkovic, Dejan, Chew, Min Hoe, Koh, Frederick, Ngu, James, Panyko, Arpád, Bele, Uros, Košir, Jurij Aleš, Daoud, Hassan, Bravo, Ana Maria Minaya, Jayarajah, Umesh, Wickramasinghe, Dakshitha, Adam, Mohammed Elmujtba Adam Essa, Rutegård, Martin, Sund, Malin, Adamina, Michel, Gialamas, Eleftherios, Horisberger, Karoline, Alshaar, Muhammad, Huang, Abel, Lohsiriwat, Varut, Charles, Shane, Jlassi, Haithem, Isik, Arda, Lekuya, Hervé Monka, Kopetskyi, Slava, Alsaadi, Hayder, Alshryda, Sattar, Alser, Osaid, Bankhead‐kendall, Brittany, Breen, Kerry, Mashbari, Hassan, Cal, Fernando Bonilla, Al‐naggar, Hamza, Maimbo, Mayaba, Mazingi, Dennis, Abbott, Tom, Akhbari, Melika, Benson, Ruth, Bhanderi, Shivam, Biccard, Bruce, Caruana, Edward, Chakrabortee, Sohini, Chapatwala, Reema, Costas‐chavarri, Ainhoa, Demetriades, Andreas K, Desai, Anant, Di Saverio, Salomone, Drake, Thomas, Edwards, John, Evans, Jonathan, Fiore, Marco, Ford, Samuel, Fotopoulou, Christina, Fowler, Alexander, Futaba, Kaori, Ganly, Ian, James, Harelimana Grace, Griffiths, Ewen, Gronchi, Alessandro, Hutchinson, Peter, Hyman, Gabriella Yael, Incorvia, Joseph, Jain, Ritu, Jenkinson, Michael, Khan, Tabassum, Knight, Stephen Richard, Kolias, Angelos, Kudsk‐iversen, Søren, Kwan, Tsun Yu, Leung, Elaine, Mayol, Julio, Mckay, Siobhan, Meara, John G., Mills, Emily, Moug, Susan, Patel, Akshay, Perinotti, Roberto, Rice, Henry E., Roberts, Keith, Schache, Andrew, Shaw, Richard, Smart, Neil, Stephens, Matthew, Stewart, Grant D., Teasdale, Ella, Vaughan‐shaw, Peter, Vidya, Raghavan, Wright, Naomi, Zimmelman, Natalie, Agastra, Ervis, Thereska, Dariel, Lucchini, Sergio Martin, Laudani, Veronica, Chwat, Carina, Salazar, Ivana Ines Pedraza, Pantoja Pachajoa, Diana Alejandra, Duro, Agustin, Arancibia, José Alfredo Calderón, D’Aulerio, Giuliana, Dudi‐venkata, Nagendra, Egoroff, Natasha, Farik, Shebani, Lott, Natalie, Moss, Jana‐lee, Rennie, Sarah, Tan, Lorwai, Uyen Giao, Vo, Watson, David, Watters, David, Bright, Tim, Hollington, Paul, Zhou, Xuanyu, Kroon, Hidde M, Farfus, Anthony, Barker, John, Watson, Eleanor, Stevens, Sean, Latif, Haider, Dawson, Amanda Caroline, Chuan, Alwin, Muralidharan, Vijayaragavan, Wong, Enoch, Ackermann, Travis, Pacilli, Maurizio, Hodgson, Russell, Heriot, Alexander, Choong, Peter, Brown, Wendy, Lidder, Surjit, Yeung, Justin, Traeger, Luke, Regalo, Guillermo, Gourlay, Ralph, Badiani, Sarit, Koh, Cherry, Putnis, Soni, Haider, Fayza, Mitul, Ashrarur Rahman, Komen, Niels, Dhondt, Bert, Cappeliez, Serge, Pigeolet, Manon, Schoneveld, Martijn, Stijns, Jasper, Oosterlinck, Wouter, Flamey, Nicolas, Kpangon, Cyrille, Agbadebo, Mouhamed, Tobome, Smèvo Romaric, Barros, Aldo Vieira, Júnior, Samuel Aguiar, Amaral Campos, Heloisa Galvão, Gross, Jefferson, Coimbra, Felipe José Fernandez, Kowalski, Luiz Paulo, Makdissi, Fabiana, Nakagawa, Suely, Neto, Joao Pedreira Duprat, Vartanian, Jose Guilherme, Yazbek, Guilherme, Zequi, Stenio C, Flumignan, Ronald, Jaworska, Natalia, Dell, Angela, Shanthanna, Harsha, Behzadi, Abdollah, Nessim, Carolyn, Mozel, Michelle, St‐germain, Pascal, Russell, Crispin, Groot, Gary, Safieddine, Najib, Wijeysundera, Duminda, Eskander, Antoine, Chadi, Sami, Mackenzie, Shawn, Flexman, Alana, Heredia, Fernando, Villanueva, Julio, Waissbluth, Sofia, Macchiavello, Roberto, Escudero, Mario I, Fuentes, Tyare, Mimica, Ximena, Saenz, Dinimo Bolivar, Caicedo, Lina, Alzate, Juan Pablo, Luna, Joaquin, Alonso, Nestor Fabian Pedraza, Silva, Camilo Ortiz, Rodriguez, Juliana, Silva‐igua, Liliana, Torres, Martha Luz, Trujillo, Lina María, Calvache, Albaro José Nieto, Balanta‐melo, Julián, Figueroa‐casanova, Rafael, García‐montoya, Oscar‐julián, Toro, Carlos Andres Marulanda, Botero, Marcela Velez, Arango, Maria Clara Mendoza, Martinez, Eneida Diaz, Perdomo, Valentina Gutiérrez, Montenegro, Emileth, Rodriguez‐abreu, Julia, Mejía, Dolores, Abouelnagah, Galal, Shehata, Sameh, Rida, Ahmed Hossam Eldin Fouad, Hassan, Ramy A., Saad, Mahmoud M., Loaloa, Mohamed Reda, Mostafa, Badr, Qassem, Mohamed, Fahmy, Mohamed, Abozied, Hesham, Azzam, Ahmed Y, Ghozy, Sherief, Sallam, Asser, Shehta, Ahmed, Abdelkhalek, Mohamed, Samaka, Rehab, Morsy, Amr, Sherif, Ahmed Elshawadfy, Negussie, Abraham, Fisseha, Tigist, Shumbash, Kibruyisfaw, Abebe, Metasebia, Yasin, Seid Mohammed, Akililu, Yemisirach Bizuneh, Megersa, Abebe, Tefera, Teshome, Assefa, Melatework, Atnafu, Bahru, Tsegaye, Bereket, Bezabih, Yoseph Solomon, Sisay, Silamlak, Bekele, Kebebe, Jira, Moa, Derilo, Habtamu, Degefa, Eyueal, Tadesse, Anteneh, Nidaw, Melkamu, Sarjanoja, Elise, Testelin, Sylvie, Boucher, Sophie, Jouffret, Lionel, Lakkis, Zaher, Le Bian, Alban Zarzavadjian, Harper, Luke, Déserts, Marc Danguy, André, Benoît, Slim, Karem, Verhaeghe, Romain, Police, Andrea, Girard, Edouard, Chebaro, Alexandre, Nkembi, Armande Subayi, Arnalsteen, Laurent, Ballouhey, Quentin, Mege, Diane, Jeandel, Clement, Duchalais, Emilie, Bouche, Pierre‐alban, Manceau, Gilles, Crétolle, Célia, Hervieux, Erik, Girard, Noémie, Seguin‐givelet, Agathe, Gaujoux, Sebastien, De Simone, Belinda, Boisson, Matthieu, Bergeat, Damien, Fredon, Fabien, Nappi, Francesco, Kassir, Radwan, Scalabre, Aurélien, Migliorelli, Federico, Ezanno, Anne‐cecile, Seeliger, Barbara, Vaysse, Charlotte, Charbonneau, Helene, Misrai, Vincent, Abbo, Olivier, Angeles, Martina Aida, Brunaud, Laurent, Modabber, Ali, Wolf, Sebastian, Kamphues, Carsten, Höhn, Philipp, Glowka, Tim R., Rokohl, Alexander Christopher, Bork, Ulrich, Fluegen, Georg, Horch, Raymund E., Schmedding, Andrea, Schnitzbauer, Andreas, Eberbach, Helge, Schlager, Daniel, Spelsberg, Fritz, Keppler, Lena, Hecker, Andreas, Wolfer, Susanne, Ronellenfitsch, Ulrich, Nitschke, Christine, Peiper, Christian, Hakami, Ibrahim, Welter, Stefan, Nikolaieva, Karine, Roth, Andreas, Lindert, Judith, Gousias, Konstantinos, Rissmann, Anke, Linz, Valerie Catherine, Rahbari, Nuh, Rassweiler‐seyfried, Marie‐claire, Gut, Anna Eleonora, Gempt, Jens, Reim, Daniel, Wagner, Arthur, Keppler, Alexander M., Stoleriu, Mircea Gabriel, Saier, Tim, Stadler, Josef, Kaiser, Julia Christina, Brunner, Stefan M., Pfister, Karin, Herzberg, Jonas, Nowak, Kai, Reinhard, Tobias, Stavrou, Gregor A., Königsrainer, Alfred, Konrads, Christian, Quante, Markus, Laban, Simon, Pusch, Silke, Hirschburger, Markus, Doerner, Johannes, Wiegering, Armin, Tampaki, Ekaterini Christina, Ruiz, Alitza Gutiérrez, Rodas, Alejandra, Portilla, Ana Lucía, Carrera, Jacqueline, Duarte, Amalia Barrios, Lowey, Megan, Barillas, Sabrina, Suroy, Atul, Vaishnav, Dhaivat, Chowdappa, Raghunandan Gorantlu, Madabhavi, Irappa, Bhat, Dhananjaya, Venkatappa, Sunil Kumar, Thakar, Sumit, Jain, Kavitha, Kumar, Aruna, Nagar, Manoj, Mishra, Tushar, Sekar, Arunkumar, Gupta, Anand, Kaman, Lileswar, Karthigeyan, Madhivanan, Tripathi, Manjul, Rammohan, Ashwin, Vayoth, Sudheer Othiyil, Rajanbabu, Anupama, Subbian, Anbukkani, Gupta, Rahul, Raut, Monish, Evelyn, Nissi, Kannaiyan, R Lavanya, Matai, Anil, Misra, Sanjeev, Bhende, Vishal, Muthu, Sathish, Ghosh, Indranil, Sharma, Abhishek, Bajaj, Ankur, Rajan, Shiv, Agarwal, Gaurav, Pawar, Pranay, Alexander, Philip, Vijayakumar, M Vijayakumar, Hameed, Zeeshan, Badareesh, L, Chaudhry, Navneet Kumar, Baliarsing, Lipika, Dharap, Satish, Kulkarni, Amruta, Thyavihally, Yuvaraja, Sharma, Rahul Deo, Pramesh, C S, Soni, Rajesh, Dube, Surya Kumar, Sharma, Shilpa, Singh, Harvinder, Bains, Lovenish, Ghodke, Rahul, Kumar, Ashwani, Sodhai, Vivek, Maji, Suvendu, Basu, Somprakas, Mahakalkar, Chandrashekhar, Kannan, Ravi, Mehraj, Asif, Ranganath, N, Phadnis, Ashish, Yadev, I, Kavalakat, Alfie, Mittal, Rohin, Vallam, Karthik Chandra, Akhavizadegan, Hamed, Maleki, Esmaeil Rezghi, Kandevani, Naser Yousefzadeh, Ikele, Hilary, Mcnestry, Catherine, Fleming, Christina, O’Brien, Stephen, Elwahab, Sami Abd, Davis, Niall, Javadpour, Mohsen, Mcdonnell, Brendan, Connor, Clare O, Bolger, Jarlath, Clancy, Cillian, Croghan, Stefanie M, Donlon, Noel, Cullinane, Carolyn, Creavin, Ben, Muheilan, Muheilan, Earley, Helen, Kabir, Syed Mohammad Umar, Fahadullah, Muhammad, Ryan, Éanna, Connelly, Tara, Hashimoto, Daisuke, Alqudah, Majdi Ali, Alajalen, Amer, Omari, Rand Y., Qasem, Abdulrahman, Alawneh, Yazan, Ahmad, Amer, Aladawi, Omar, Alrayes, Bourhan, Haidar, Hanan, Husain, Shatha, Qassem, Faisal, Sumadi, Adnan, Salhiyeh, Ala’a Abu, Al‐manaseer, Balqees Mahmoud, Alsunna, Zaid, Ra’Ed, Hazim, Hamad, Faten Reyad Bani, Abuleil, Amro, Jimaale, Elmi Ahmed Mohamed, Abu‐mehsen, Marah, Olaywah, Noor, Wafi, Omar, Ababneh, Hazim, Abu‐ismail, Luai, Khamees, Almu’Atasim, Alkhatib, Ahmad, Bolatbekova, Raikhan, Kulimbet, Mukhtar, Nurgozhin, Talgat, Saliev, Timur, Zhussupov, Baurzhan, Almabayev, Ydyrys, Kaidarova, Dilyara, Tamoos, Khalil, Aqeelah, Ahmed, Mohammed, Alsnosy Abdullah Khalefa, Al Maadany, Faraj, Alkadeeki, Ghadah, Gahwagi, Milad, Aldressi, Wafa, Amnaina, Mohamed, Alansari, Arowa Hassan Abdulrahman, Alkaseek, Akram, Yagoub, Ghozlan, Amer, Anass Ben, Salem, Marwa, Almugaddami, Ayman, Burgan, Dania, Abdelkabir, Mohammed, Alshareef, Khayriyah, Islam Ben Jouira, Rayet, Meelad, Ayman, Bouhuwaish, Ahmad, Dwaga, Sumayya Essayah, Khalifa, Houda, Almiqlash, Bushray, Suliaman, Taha, Alawami, Mohammed, Elhajdawe, Fras, Aboazamazem, Hajir, Ellojli, Ibrahim, Msherghi, Ahmed, Saleh, Ismail Ali, Alayan, Mohammed, Ndayishyigikiye, Marcel Didier, Munyika, Akutu, Plarre, Philipp, Borowski, David W, Wells, Cameron, Teague, Rebecca, Elliott, Brodie, Kieser, David, Mohyieldin, Omar, Mcintosh, Nick, Haran, Cheyaanthan, King, Jasmin, Jeong, Ha, Mcguinness, Matthew James, Adesanya, Opeoluwa, Olaogun, Julius, Akinmade, Akinola, Bwala, Kefas, Agbonrofo, Peter, Afolabi, Akinwale, Usang, Usang, Ekenze, Sebastian, Olori, Samson, Lawal, Taiwo Akeem, Okunlola, Abiodun, Kache, Stephen, Sale, Danjuma, Anyanwu, Lofty‐john, Okereke, Chukwuma, Tolani, Musliu Adetola, Filipce, Venko, Todorovic, Lazar, Stavridis, Sotir, Massoud, John George, Alsibai, Sareyah, Sultan, Rizwan, Altaf, Humera Naz, Bhatti, Abu Bakar Hafeez, Waqar, Shahzad Hussain, Aziz, Aliya, Kerawala, Asad Ali, Rai, Lajpat, Anwer, Mariyah, Tariq, Aiman, Ayub, Bushra, Niazi, Sami Ullah, Naseem, Muhammad Yasir, Sarwar, Muhammad Zeeshan, Khokhar, Muhammad Imran, Zahid, Imdad Ahmad, Majid, Haroon Javaid, Talat, Nabila, Asif, Muhammad, Chaudhary, Muhammad Hamid, Farooq, Umer, Ahmad, Siddique, Mabood, Waleed, Bukhari, Syed Imran, Tariq, Muhammad, Yaqoob, Eesha, Javed, Saad, Malik, Muhammad Usman, Yaqoob, Hassan Nawaz, Pacheco, Glenda Marina Falcon, Melendez, Robinson Mas, Urbina, Arazzelly Del Pilar Paucar, Chiuyari, Jose Rios, Alvarado, Carlos Eduardo Otiniano, Lau, Lorena Fuentes Rivera, Borda‐luque, Giuliano, Niquen‐jimenez, Milagros, Arias, Claudia, Zegarra, Sergio, Pallardel, Jenner Betalleluz, Oscco, Regina Amparo Ugarte, Mendiola, Gian, Colmenares, Yahaira Tatiana Carpio, Zapata, Carlos Shiraishi, Ortiz, Maria Rosa, Borges, Filipe Castro, Viveiros, Octavio, Serralheiro, Pedro, Santos‐costa, Paulo, Mendes, Filipa, Melo, Miguel Rocha, Cardoso, Paulo, Soares, Ana, Pereira, Rita Gonçalves, Silva, Nelson, Caiado, André, Sacras, Maria Luís, Azevedo, Pedro, Almeida‐reis, Rui, Oliveira, João, Nogueiro, Jorge, Sampaio‐alves, Mafalda, Costa, Luciana Cidade, Baía, Catarina, Deus, Ana Cláudia, Branquinho, Rita, Marçal, André, Tojal, André, Makkai‐popa, Silviu Tiberiu, Mironescu, Aurel, Grama, Florin, Toma, Elena Adelina, Filipescu, Daniela, Bacalbasa, Nicolae, Motas, Natalia, Ionescu, Sebastian, Ginghina, Octav, Costea, Radu, Zarnescu, Narcis Octavian, Drasovean, Radu, Dimofte, Mihail‐gabriel, Porumb, Vlad, Kirov, Mikhail, Molitvin, Yegor, Pykhteev, Vadim, Raevskaya, Marianna, Butyrskii, Aleksandr, Alshahrani, Mushabab, Althumairi, Azah, Alzerwi, Nasser, Al Ameer, Ahmed, Madkhali, Tariq, Almulhim, Abddulrahman Saleh, Ghazwani, Salman, Ayoub, Abdu, Iskander, Othman, Ghunaim, Mohammed, Alharthi, Mohammed, Alzaidi, Turki M, Alyami, Mohammad, Al Amri, Abdulrahman, Alfakhri, Abdullah, Alhefdhi, Amal, Chowdhury, Sharfuddin, Nouh, Thamer, Alshehri, Ameen, Alzahrani, Abdulrahman, Alalawi, Yousef, Awad, Selmy, Konate, Ibrahima, Tendeng, Jacques, Teo, Nan Zun, Aqil, Sabra, López, Cristina Barrena, Mozo, Ana Sánchez, Infante, Antonio Rodriguez, Vivancos, Patricia Caja, Prieto, Mikel, Roman, Igor Alberdi San, Fernandez, Laura Gomez, Vives, Josep Maria Muñoz, Carreras‐castañer, Anna, Díaz‐feijoo, Berta, Sieira‐gil, Ramon, Turrado‐rodriguez, Victor, López, Anna Sánchez, Sánchez‐cabús, Santiago, Toscano, Marta Jimenez, Sin, MªPilar Canals, Laura, Saura García, Sole, Oriol Martin, Bellver, Pedro Palazon, Pérez‐bertólez, Sonia, Prat‐ortells, Jordi, Martínez, Mireia Riba, Rubio‐palau, Josep, Tarrado, Xavier, Nuñez, Jorge, Mendoza, Veronica Alonso, Bescós, Coro, Espin‐basany, Eloy, Espinosa‐bravo, Martin, Gil‐sala, Daniel, González‐suárez, Susana, Estruch, Nuria Montferrer, Mariño, Lucia Porteiro, Rodríguez‐tesouro, Ana, Portilla, Fabian Rojas, Pérez, M Pilar Tormos, Vives, Inmaculada, De Cortazar, Unai Garcia, Tudela, Kiara, Landaluce‐olavarria, Aitor, Gómez, Mercedes Estaire, Almoguera, Jorge, Ugarte‐sierra, Bakarne, Jimenez, Virginia, Bertrand, Marta, Puiggrós, Laura Cárdenas, Delisau‐puig, Olga, Garcia‐adamez, Jorge, Bergkvist, David Julià, Maldonado‐marcos, Eloy, García, Lucia Diego, Golet, Marta Roldón, Soto‐darias, Iván, Rahy‐martín, Aida Cristina, Enjuto, Diego, Ramos‐luengo, Adolfo, Fernandez, Juan Delgado, Duarte, Carolina Lugo, Thies, Cristina Ojeda, Marquez, Lucila, Vita, Diana Crego, Dziakova, Jana, Velasco, Jorge Caño, Mateo‐sierra, Olga, Quintana‐villamandos, Begoña, Valcarcel, Cristina Rey, Rio, Javier, León, Laura Román García, Di Martino, Marcello, Prada, Jorge, González, Javier Serrano, Losada, Manuel, Gomez, Jose Tomas Castell, Corripio‐sanchez, Ramon, Forero‐torres, Alexander, Morales‐puebla, José Manuel, Perez‐chrzanowska, Hanna, Gonzalez, Santiago Valderrabano, Yebes, Alvaro, Zapardiel, Ignacio, Alonso, Manuel Diez, Palacios, Nelson Morales, Sánchez, Alberto Cabañero, Fernández, Fátima Sánchez, Gurumeta, Alfredo Abad, Abad‐motos, Ane, Corella, Fernando, Ripollés‐melchor, Javier, Sanz‐gonzalez, Rosa, Fuentes, Marta Alcaraz, Martín, Maria Teresa Fernández, Espino, Pablo Calvo, Prats, Milagros Carrasco, Fernández‐lópez, Antonio‐josé, Escudero, Damián García, Soria, Vanesa Garcia, Alonso, Jesús Aarón Martínez, Ruiz‐marín, Miguel, Pérez, Beatriz Gómez, Moya‐angeler, Joaquin, Martínez, Daniel Fernández, Bayo, Heura Llaquet, Colás‐ruiz, Enrique, Romera, Susana Bella, Pellicé, M. Teresa Gavaldà, Solé, Misericòrdia Jordà, Velasquez, Enrique Jose Ruiz, Núñez, Bernardo, Jimenez, Raul, Zabaleta, Jon, González‐gimeno, Maria Jose, Vázquez, Irene Ortega, Ferrer, Antonio Perez, Martín‐láez, Rubén, Suarez, Marcelo Moreno, Eiras, Miguel Angel Freiria, Ramallo‐solís, Irene, Gomez‐rosado, Juan‐carlos, Guillen, Jose Ramon Oliver, Boira, Mar Achalandabaso, Bauset, Juan Carlos Catalá, Domenech, Julio, Badenes, Rafael, Bernal‐sprekelsen, Juan Carlos, Sancho‐muriel, Jorge, De Andrés‐Asenjo, Beatriz, Tejero‐pintor, Francisco J, Vallve‐bernal, Marc, Melero, Alba Vazquez, Blasco, Laura Sánchez, Escartin, Jorge, Mallén, Victoria Duque, Srishankar, Selvaratnam, Sooriyabandara, Charitha, Basnayake, Oshan, Gunawansa, Nalaka, Weeraddana, Prabuth Dulanjan, Vimalakanthan, Thanusan, Gishanthan, Shanthamoorthy, Chandrasinghe, Pramodh, Sauvain, Marc‐olivier, Ghazal, Ahmad, Al‐sabbagh, Yusra, Alhassoun, Turki, Albared, Sara Maa, Naem, Antoine, Alnahr, Hareth, Jisry, Ghassan, Hammed, Ali, Xaviour, Okedi Francis, Turinawe, Gaston, Mubezi, Isaac, Sikakulya, Franck K., Kakeeto, Andrew, Kabweru, Wilberforce M., Kiweewa, Ronald, Matovu, Paul, Isaac, Otolia, Mashhour, Mohamed, El Helw, Amin, Kherani, Safeena, Mohamed, Awadelkarim, Abbas, Ferial Mohamed Ali, Mohammed, Diary, Aldlyami, Ehab, Kundra, Rakesh, Michael, Antony Louis Rex, Khalil, Kareem S., Dbeis, Rachel, Shaikh, Shafaque, Ferry, Jenny, Jamal, Aiman, Siddique, Haleema, Das, Rishi, Ponugoti, Nikhil, Rattanasirivilai, Pornjittra, Sultana, Asma, Mosley, Frances, Chan, Matthew, Bateman, Antony, Davies‐jones, Gareth, Georgiades, Fanourios, Ahmadi, Navid, Coonar, Aman, Baig, Mariam, Khatri, Chetan, Surendran, Arthika, Sonksen, Julian, Sinnerton, Robert, Brennan, Caitlin, Faulkner, Gemma, Greenhalgh, Michael, Emerson, Hannah, Singisetti, Kiran, Totty, Joshua, Wilson, Michael, Terence, Lo, Corbett, Harriet, Okonkwo, Ijeoma, Arbane, Gill, Kerawala, Cyrus, Parmar, Chetan, Bath, Michael, Odejinmi, Funlayo, Sagar, Jayesh, Talwar, Rishi, Newman, Samuel, Hammond, John, Moir, John, Duric, Natalie, Szakmany, Tamas, Talib, Ahmar Iftikhar, Youssef, Mina, Lewis‐lloyd, Christopher, Lami, Mariam, Ayub, Khurram, Dean, Benjamin, Balasubramanya, Supriya, Lakpriya, Sathya, Rogers, Luke, Turner, Paul, Maher, Mark, Sigamoney, Kohila, El Kafsi, Jihène, Hardie, John, Johnson, David, Henein, Christin, Hollyman, Marianne, Agarwal, Ketan, Powell, Simon, Chauhan, Govind Singh, Patel, Rakesh, Gagnier, Joel, Carmichael, Heather, Aurora, Null, Olson, Kristofor A., Etchill, Eric, Hirji, Sameer, Naunheim, Matthew, Drake, Frederick, Reinke, Caroline, Alecci, Anna, Vaysburg, Dennis, Rodriquez, Jennifer, Shih, Emily, Ban, Vin Shen, Coleman, Julia, Kaups‐fresno, Krista, Giorgakis, Emmanouil, Dinome, Maggie, Bhutiani, Neal, Alnachoukati, Omar, Aiken, Taylor, Diehl, Thomas, Gosain, Ankush, Rattan, Rishi, Ghani, Muhammad Owais Abdul, Ruzgar, Nensi Melissa, Liveris, Anna, Glass, Nina, Paranjape, Charu, Chin, Theresa, Meola, Antonio, Nicholson, Kristina, Squiers, John, Lueckel, Stephanie, Reisenauer, Janani, Callcut, Rachael, Mansour, Ahmed, Berndtson, Allison, Kornblith, Lucy, Seegert, Sara, Martins, Paulo, Al‐shehari, Mohammed, Al‐raimi, Ibrahim, Ngulube, Allan, Siamuchembu, Maphios, Mushiwokufa, Willard, Mlambo, Busisiwe, Chinyowa, Simbarashe, Bollano, Enton, Gjyli, Kostandin, Kerpaci, Jola, Vrapi, Enxhi, Zijaj, Lorena, Djahida, Bahraoui, Zohra, Belabbes Fatima, Khadidja, Kouidri, Bali, Oussama, Benallel, Nassim, Lalmi, Ismahene, Abdoun, Meriem, Aouabed, Nesrine, Bouaoud, Souad, Bouchenak, Kamel, Haif, Assia, Soualili, Zineddine, Bastet, Joaquin, Bianco, Agustín, Capitaine, Daniel, Lozada, Jorge Centeno, Esquivel, Carlos, Figueroa, Rodrigo, Garcia, Manuel, García, Pablo Martín, Gerchunoff, José Ignacio, Iascano, Fernando Martinez, Mondino, Jose, Muriel, María Emilia, Pablo, Carmignani, Passadore, Martin, Tornini, Alejandra, Traverso, Rogelio, Vargas, Lara, Zanoni, Gerardo, Berber, Norberto, Cotta, Estefanía, Di Vincenzo, Marcela, Gallino, Esteban Sebastian, Gigena, Cecilia, Grassano, Bianca, Lugones, Ignacio, Madrid, Constanza, Maricic, Maximiliano, Martinez, Antonio Alberto, Rosso, Andres, Scher, Pablo, Tachella, Sofia, Zezular, Damaris Idara Anabel, Abuawad, Carla, Forneris, Agustin Albani, Allemand, Carola, Calzaretta, Laura Gisela Alvarez, Boretto, Jorge G., Boudou, Rocio, Brandariz, Rodrigo, Buljubasich, Martin, Burchakchi, Arturo, Buttaro, Martin, Campana, Juan Pablo, Busnelli, Virginia Cano, Carminatti, Tomas, Lalín, Agustina Florencia Castro, Cereghini, Julian, Amor, María Sol Crespi, Croattini, Roberto Sebastián, Fernandez, Maria Sol, Figari, Marcelo, Fraidenraij, Uriel, Gallegos, Diego, García‐mansilla, Agustín Maria, Gonzalez, Marcos, Gonzalez, Matias Ignacio, Salazar, Esteban Gonzalez, Goransky, Jeremias, Gauna, Guillermo Hernandez, Higuera, Felipe, Holc, Fernando, Jauregui, Esteban Gabriel, Larrañaga, Juan, Liyo, Juan, Llano, Lionel, Lobos, Pablo, Luzzi, Emilia, Mastroianni, Gustavo, Mata‐suarez, Santiago Miguel, Mayer, Horacio F., Loughlin, Santiago Mc, Mendoza, Efrain, Mentz, Ricardo Esteban, Mercado, Pedro, Moyano, Pablo, Noll, Florencia, Odetto, Diego, Oliva, Agustina Rene, Vidal, Rafael Perez, Poggi, Catalina, Premoli, Eduardo Jorge, Ramos, María Lourdes, Rosas, Patricio, Rossi, Luciano, Rossi, Gustavo, Saadi, Jose, Scherñuk, Jordán, Slullitel, Pablo, Stang, María Verona, Taboada, María Victoria, Tirapegui, Sebastian, Uffelmann, Constanza, Vaccaro, Carlos, Vagni, Roberto, Valerio, Ana Clara, Zarratea, Celeste Soledad, Montal, Silvina, Morris, Brian, Valdez, Pedro, Diaz‐couselo, Fernando, Sabatini, Luciana, Alvarez, Fernando Andres, Avila, Micaela, Benitez, Nicole Benitez, Bruera, Nicolás, Doniquian, Marcelo, Gielis, Manuel, Liaño, Julian, Llahi, Florencia, Mandojana, Facundo, Páez, Walter, Parodi, Matias, Molina, Héctor Picon, Pinsak, Agustin, Viscido, German, Badra, Roberto, Belisle, Diego, Borla, Hernan, Eberle, Georgina, Esteban, Agustin, Ferrero, Carlos Ignacio, Furlan, Micaela, García, José Sebastian, Granero, Lucas, Henzenn, Mariel, Juaneda, Rodrigo, Vidal, Esteban Politi, Reyna, Guillermo Romero, Montero, José Gabriel Yaryura, Caubet, Maria Mercedes, D’Addino, José Luis, Daryanani, Deepu, Gosselink, Martijn, Ponson, Alex, Afzal, Mohamed, Amprayil, Mathew, Brooke‐smith, Mark, Chen, John, Grantham, James, Gricks, Benjamin, Hii, Amanda, Kundu, Nikhil, Liu, David, Livingston, Charles, Marshall‐webb, Matthew, Mcveay, Christina, Moore, Hamish, Nair, Gavin, Ong, Bee Shan, Parker, Dominic, Rudolph‐stringer, Victoria, Szpytma, Malgorzata, Vissapragada, Ravi, Wee, Melissa Yun, Wong, Geoffrey Yuet Mun, Barnett, Dylan Richard, Bochner, Melissa, Bolt, John, Buddingh, Karel, Coventry, Brendon, Davis, Sean, Dawson, Joseph, Denham, Stuart, Dobbins, Christopher, Fitridge, Robert, Gan, Siang Wei, Haque, Izhar‐ul, Herath, Matheesha, Jog, Shivangi, Kanhere, Harsh, Kuang, Beatrice, Lam, Yick Ho, Lambert, Virginia, Lim, Alicia, Maina, Grace, Moller, Cea‐cea, Neo, Eu Nice, Neo, Eu Ling, Nguyen, Alain, Prasad, Shalvin, Roy, Jennifer, Russell, Christine, Sammour, Tarik, Smith, Nicholas, Smith, Richard, Stranz, Conrad, Tourani, Saam, Tran, Steven, Van de Ven, Lucinda, Warren, Leigh, Whitfield, Robert, Wormald, Jamie, Yin, Yijie, Bierton, Christopher, Cribb, Benjamin, Foley, Katarina, Ong, Daniel, Watson, Matthew, Hampton, Jacob, Karam, James, Rugendyke, Anya, Zhang, Tyson, Vasey, Carolyn, Apellaniz, Eduardo, Frankel, Adam, Gahan, Lara, Guerra, Glen R, Liesegang, Amanda, Lutton, Nicholas, Maurice, Andrew, Miron, Scott, Prasad, Aveechal, Sercombe, Ashleigh, Sivapalan, Thanusan, Ahmad, Syed Danial Syed, Tee, Chin Li, Yaksich, Lachlan, Batstone, Martin, Breik, Omar, Young, Thomas, Field, Michael, Scott, Benjamin, Charlton, Gabriella, Chen, Si, Cheung, Henry Yan Chi, Gauri, Neha, Hayhurst, Ross, James, Sophie, Jang, Seyoung, Jia, Fangzhi, Zhang, Helen, Aujla, Randeep, Finsterwald, Michael, Percy, Digby, Tanaya, Alvin, Trivedi, Anand, Aylett, Andrew, Grills, Richard, Holmes, Angela, Kwok, Matthew Ming Kei, Lambers, Anton, Lambers, Leo, Lok, Evania, Nagra, Sonal, Page, Richard, Paltoglou, Nicholas, Panuganti, Vishwakar, Riddell, Sophie, Rudock, Gareth, Tan, Hannah, Underwood, Kirk, Youssef, Daniel, Amoils, Ricci, Bahtigur, Nazli, Bengeri, Savitha, Builth‐snoad, Lily, Cheah, Hock Ping, Chen, Paul, Chew, Kenneth, Chong, Alyssa, Clark, Sara, Kaul, Rhea Darbari, Devan, Eliya, Ewington, Christina, Fatima, Aleeza, Fitt, Sophia, Gaul, John, Ghosal, Paloma, Gojnich, Amy, Gunawardena, Indu, Hamer, Peter, Holmes, Samuel, Hou, Zhen, Jolly, Danielle, Kane, James Dimitri, Kaufman, Micayla, Khandelwal, Tanishq, Khanijaun, Sukhwant, Kwok, Kelvin, Latif, Edward, Laura, Sharon, Lee, Vivian, Leung, Catherine, Liang, Ina, Lin, Peter, Lun, Elizabeth Weng Yan, Luo, Haili, Victor, Ly, Jolande, Ma, Macnab, Brooke, Mcgee, Richard, Miles, Stephanie, Munro, William, Narroway, Harry, Ngan, Tin Yau, Noor, Anthony, Pahalawatta, Upuli, Park, Melissa, Parkin, Cameron, Poon, Rita, Somasundaram, Shanmugam S, Saab, Claudia, Simpson, Renwick, Steinel, Dana, Taylor, Emily, Tchen, Adrian, Thong, Shu, Tran, Kelvin, Tree, Kevin, Vance, Lucille, Wong, Ken, Victor, Yu, Zhang, Michael, Cox, Aram, Tan, David Chi Hau, Thani, Nova, Das, Shefali, Macdonald, Taigh, Salama, Paul, Sandhu, Gagandeep, Shadbolt, Rachel, Phan, Du, Townend, David, Eunmaro, Ju, Lee, Sang Mi, Barnett, Stephen, Kheslat, Hajar Hasan, Higgins, Andrew, Jamieson‐grigg, Chloe, Jenkins, Victoria, Larner, Brett, Perini, Marcos, Proud, David, Qin, Kirby, Riddiough, Georgina, Seevanayagam, Sivendran, Damien M., Wu, Zhao, Chris, Aggarwal, Sonali, Vinna, An, Battershell, Melanie, Chan, Elliot, Cheung, King Tung, Drake, Anna, Goonawardena, Janindu, Hunt, Benjamin, Christopher, Ip, Iyer, Vikram, Jain, Anshini, Kealey, Joshua, Lew, Chen, Lim, Christopher Seng Hong, Luck, Tara, Mackay, Sean, Maher, Natalie, Maroske, Georgia, Roubos, Nicholas, Sengupta, Shomik, Steen, Christopher, Tsigaras, Zac, Tuttle, Zachary, Ward, Salena, Williams, Marli, Yeap, Evie, Zhou, Jessie, Coates, Amy, Mutalima, Nora, Tran, Ton, Nataraja, Ramesh, Sharpin, Claire, Bird, David, Choy, Kay Tai, Condron, Sarah, Daruwalla, Jurstine, Anjos, Isabela, El‐khoury, Hanna, Fabian, Robert, Gillard, Andrew, Greenop, Rebecca, Issa, Michael, Lee, Sharon, Mori, Krinal, Petrakis, Nikki, Qureshi, Maryum, Sabella, Danielle, Satasivam, Prassannah, Sathianathen, Niranjan, Seow, Sean Ezekiel, Shen, Amanda, Shi, Margaret, Tabassum, Meher, Teixeira, Rodrigo, Vivian‐taylor, Josephine, Wheatley, Jennifer, Shepherd, Sally, Soucisse, Mikael, King, Sebastian, O’Connor, Brendan, Teague, Warwick, Banting, Simon, Chong, Lynn, Clatworthy, Sharnel, Cochrane, Angela, Fox, Adrian, Hii, Michael Wei, Isaacs, Anna, Johnson, Mary Ann, Knowles, Brett, Newcomb, Andrew, Price, Veronique, Raman, Jaishankar, Read, Matthew, Rowcroft, Alistair, Taylor, Lillian, Wright, Gavin, Chana, Prem, Shaw, Kalai, Bock, Jacob, Cory, Jordan, Drummond, Katharine, Lahy, Jack, Mcintire, Thomas, Price, Benjamin, Stark, Claire, Besson, Alex, Gartrell, Richard, Lauritz, Brianne, Nguyen, Ha My Ngoc, Ong, Chui Foong, Pitcher, Meron, Scullion, Lorna, Tang, Howard, Taylor, Danielle, Wolf, Brigid, Wichmann, Matthias, Davis, Amelia, Maurel, Amelie, Raubenheimer, Kyle, Campbell, Cassidy, Colaco, Ashley, Machado, Maria Julia Corbetta, Heffernan, Abbie, Karihaloo, Costa, Ludbrook, Isabella, Park, Sean SW, Peerally, Bibi Nabeeha, Singhai, Camila, Stevens, Heidi, Vavilov, Sergey, Aubin, Anne‐marie, Harris, Margaret, Lim, Zhi Ying, Spring, Rebecca, Stieler, Melissa, Barnes, Nicholas Adamson, Alam, Ahmad Seraj, Alsoudani, Ali, Amico, Francesco, Anning, Rebecca, Balogh, Zsolt J., Blatt, Alison, Cairns, Scott, Carroll, Jesse, Caterson, Andrew, Christie, Adam, Cope, Daron, Dale, Tyson, Dennis, Grace, Duggal, Anchal, Ennis, Brendan, Fenton, Mark, Yi Xin Joanna, Fu, Galevska‐dimitrovska, Ana, Gani, Jonathan, Gelzinnis, Scott, Gramlick, Madelyn, Hadlow, Claudia, Hardstaff, Ruth, Heer, Munish, Holmes, Merran, Hone, Bridget, Sophie, Hu, Huang, Linna, Iqbal, Ramiz, Jefferson, Niall, Kasthurirathne, Dimithi, Kuo, Stephen, Lau, Wayne Yan, Liang, Hsin‐ping, Lim, Daniel, Lin, Rosalina, Mcdonogh, Jack, Mcilwain, Elysse, Ming, Yan Joyce, O’Neill, Christine, Ocsan, Ryan James, Oosthuizen, Benjamin, Organ, Nicole, Otieno, James, Park, Felicity, Paterson, Amanda, Cerdeira, Marisol Perez, Peters, Luke, Petersson, Josefin, Rubbo, Sonia, Siribaddana, Venesa, Thurairajah, Kabilan, Ting, Caleb, Watson, Antonia, Way, Teagan, Wiadji, Elvina, Willoughby, Ellisha, Bailey, Ashley, Broadbent, Samuel, Narayanan, Viswanathan, Stephens, Samuel, Wilkes, Anna, Zhao, Jie, Ballal, Mohammed, D’Souza, Carl, Forbes, Clara, Goss, Matthew, Haddleton, Monique, Harty, Jacinda, Hayne, Dickon, Hew, Nicole, Koh, Wee Ling, Lee, Shawn, Malik, Shahbaz S, Abdul, Naseer Mohammed, Richards, Toby, Seow, Yi Th Ng, Wong, James, Archer, Leigh, Azaman, Nur Sabrina Binti Babe, Dilevska, Tina, Foo, Jonathan, Hans, Tasvinder, Jansen, Shirley, Kumar, Mohit, Leeson, Christopher, Pham, Terence, Pineda, Fernando Picazo, Rajakumar, Saravanan, Suk‐udom, Supisara, Tan, Jonathan, Thurston, Benjamin, Zhao, Bichen, Gupta, Shivangi, Hou, Lachlan, Jeyamanoharan, Nivedan, Leigh, James, Poh, Wei Shearn, Sala, Michael, Crothers, Rebecca, Dravid, Madhulika, Harrison, Ben, Islam, Sumayya, Mccartney, Conor, Nel, Henco, Pearson, Natasha, Apostolou, Christos, Berney, Christophe, Chou, Richard, Hanna, Sam, Lam, Andrew, Vanessa, Ma, Phanse, Salonee Shubhen, Elliott, Michael, Phung, Daniel, Barry, Jessica, Clark‐mackay, Eleanore, Cope, Jennifer, Halliwell, Richard, Chen, Ji, De Robles, Marie Shella, Llorando, Alyssa, Mahin, Humaira Haider, Rao, Dominic, Syed, Faisal, Abulafia, Daniel, Buckland, Benjamin, Cordingley, Timothy, Debiasio, Ashe, Drane, Andrew, Ireland, Patrick, Julien, Benji, Lan‐hoa, Le, Lee, Austin Yeon Suk, Loh, Eu Jhin, Middleton, Andrew, Mortimer, Brienna, Sebastian, Samuel, Short, Brooke, Stewart, Peter, Ruyven, Stephanie, Wong, Daniel, Zhang, Charry, Zhu, Bonnie, Ziaziaris, William, Leitner, Aran, Tolzman, Lukas, Zitt, Matthias, Rakos, Gergely, Székely, György, Djedovic, Gabriel, Königsrainer, Ingmar, Allmer, Caterina, Herritsch, Barbara, Mitteregger, Martin, Schauer, Christian, Seitinger, Gerald, Siebenhofer, Carmen, Uranitsch, Stefan, Duller, David, Mathew, Erwin, Skias, Christoph, Andrianakis, Alexandros, Belarmino, Armin, Brinskelle, Petra, Castellani, Christoph, Cohnert, Tina, Fediuk, Melanie, Fink, Andrea, Holzmeister, Clemens, Kahn, Judith, Kresic, Josip, Leithner, Andreas, Lindenmann, Joerg, Lumenta, David, Michelitsch, Birgit, Mikalauskas, Saulius, Nischwitz, Sebastian P., Puchwein, Paul, Roj, Andrej, Schemmer, Peter, Singer, Georg, Smolle‐juettner, Freyja‐maria, Till, Holger, Wolf, Axel, Andraschofsky, Tibor Oliver, Angerer, Rafael, Arco, Daniel, Kaufmann, Claudia, Kilic, Nura, Widschwendter, Peter, Angermann, Reinhard, Bauer, Marlies, Bergmann, Nicole, Freyschlag, Christian, Gisinger, Martin, Gollmann‐tepeköylü, Can, Graber, Michael, Haim, Alexander, Harasser, Carina, Härter, Bettina, Hirsch, Jakob, Hofer, Markus, Holfeld, Johannes, Huber, Anna Lena, Kralinger, Martina, Krappinger, Dietmar, Kuen, Marlene, Liebensteiner, Michael, Messner, Franka, Messner, Alex, Naegele, Felix, Ninkovic, Marijana, Nowosielski, Yvonne, Osl, Antonia, Ower, Cornelia, Pölzl, Leo, Rauchegger, Teresa, Reimer, Daniel, Riecke, Johannes, Schwabegger, Anton H., Sokolovski, Filipp, Strimmer, Anna, Süss, Markus, Thaler, Martin, Umlauft, Julian, Zehetner, Claus, Zeimet, Alain G., Allerstorfer, Jakob, Haslhofer, David, Hofer, Daniel, Luger, Matthias, Pisecky, Lorenz, Poier, Nikolaus, Rubicz, Nina, Schmolmüller, Christoph, Zwittag, Paul, Rossmann, Tobias, Ruiz‐navarro, Francisco, Stefanits, Harald, Elsayed, Hend, Habertheuer, Peter, Hajkova, Tereza, Loidl, Wolfgang, Luger, Ferdinand, Windischbauer, Amadeus, Fischer, Ines, Függer, Reinhold, Kirchweger, Patrick, Saini, Thomas, Berger, Julian, Fraz, Wolfgang, Nia, Arastoo, Kenez, Mihaly, Nichita, Margit, Magele, Astrid, Mayr, Thomas, Noe, Chiara, Bittner, Reinhard, Borhanian, Kurosch, Dornauer, Isabella, Emmanuel, Klaus, Gabersek, Ana, Gantschnigg, Antonia, Grechenig, Michael, Gruber, Ricarda, Hutter, Jörg, Jäger, Tarkan, Koch, Oliver, Lechner, Michael, Manzenreiter, Lisa, Mayer, Franz, Muehlbacher, Iris, Presl, Jaroslav, Rezaie, Daniel, Schredl, Philipp, Varga, Martin, Weitzendorfer, Michael, Wimmer, Angela, Brunner, Eberhard, Cillia, Michael, Gruber, Michaela, Grünbart, Martin, Heinrich, Elmar, Hoi, Hannes, Kemmetinger, Vanessa, Mittermair, Christof, Mosshammer, Victoria, Obrist, Christian, Paal, Peter, Roesch, Judith, Russe, Elisabeth, Schaetz, Tobias, Schirnhofer, Jan, Schwaiger, Karl, Wechselberger, Gottfried, Weiss, Helmut, Lanner, Maximilian, Binder, Alf‐dorian, Gürtler, Thomas, Fink, Marcus, Reichhold, Daniel, Stoyanova, Radoslava, Beitl, Klara, Bernardi, Martin H., Datler, Philip, Dawoud, Christopher, Farr, Alex, Foessleitner, Philipp, Grimm, Christoph, Harpain, Felix, Hoda, Mir Alireza, Holawe, Simone, Kranawetter, Marlene, Ott, Johannes, Perricos, Alexandra, Pesta, Maximilian, Pillerstorff, Robert, Reiterer, Christian, Riss, Stefan, Rosta, Klara, Scheriau, Georg, Tschernko, Edda, Wenzl, Rene, Wiedemann, Dominik, Wohlrab, Peter, Zapletal, Bernhard, Zimmermann, Matthias, Zimpfer, Daniel, Findl, Oliver, Fisus, Andreea, Ruiss, Manuel, Komaz, Melanie, Meindl, Nikolaus, Primavesi, Florian, Stadlbauer, Karl Heinz, Stättner, Stefan, Steiner, Florian, Cerny, Ondrej, Falkensammer, Eva, Knotzer, Hans, Köglberger, Paul, Poidinger, Bernhard, Wiesinger, Clemens Georg, Burtscher, Johannes, Rath, Sebastian, Trivik‐barrientos, Felipe, Aliyeva, Gunay, Behbudov, Vuqar, Muslumov, Gurbankhan, Zeynalov, Natiq, Alam, Mahmood, Alfayez, Fatema, Hasan, Batool, Mahdi, Maryam, Mulla, Husain, Qader, Kawthar, Saeed, Amr, Shirazi, Ahmed, Albastaki, Aysha, Birido, Nuha, Chagla, Hiba Hameed, Dawaishan, Abdulla, Dawaishan, Baheya, Farhan, Abeer, Juma, Isam, Khan, Asher, Patel, Aqsa Mohammad Eqbal, Srinivasan, Madhu, Deen, Fatema Waheed Akbar Mohamad Akbar Nawab, Abdulqadir, Seemal, Jabr, Abdulla, Maqsood, Fauzia, Almoosa, Noora, Naseer, Mai, Alam, Mohammed Shadrul, Basher, AKM Khairul, Islam, Shahnoor, Islam, S. M. Nazmul, Karim, Sabbir, Faisel, Muntasir, Khan, Sadia, Mannan, Iftekhar Ibne, Nazia, Nawshin, Bentham, Malissa, Corbin, Sasha, Doyle, Alex, Eastmond, Asha, Haynes, Amelia, O’Shea, Margaret, Phillips, Emil, Walkes, Keisha, Artyushkov, Evgeniy L., Kaplan, Mark L., Straltsov, Vladislav, Litvina, Yauheniya, Lyzikov, Alexei, Tihmanovich, Victor E., Borges, Mafalda, Brits, Tim, De Hous, Nicolas, De Wachter, Stefan, Menovsky, Tomas, Mortiers, Xavier, Vermeulen, Dorien, Vleminckx, Nils, Ysebaert, Dirk, Bontinck, Julie, Bulthé, Danny, Rasschaert, Ricky, Van Haver, Anne‐sophie, Van Belle, Koen, Verstraeten, Laurence, Vounckx, Manon, D’Ulisse, Sébastien, De Bruyne, Yasmine, El Nakadi, Badih, Heloise, Tessely, Luisetto, Matteo, Marinakis, Sotirios, Maton, Maxime, Viste, Claire, Van Daele, Elke, Vandeputte, Mathieu, Duinslaeger, Marc, Jacobs‐tulleneers‐thevissen, Daniel, Jansen, Yanina, Janssens, Ward, Kunda, Rastislav, Messaoudi, Nouredin, Ruyssers, Michael, Van Eetvelde, Ellen, Vanhoeij, Marian, Van den Eynde, Jef, Van den Eynde, Raf, Chaoui, Ahmed M., Akpla, Marcellin, Lawani, Souliath, Agossou, Hermann, Behanzin, Hulrich Aouagbe, Bokossa, Covalic, Dewanon, Hubert, Yome, Hugues, Boukari, Alassan, Gbehade, Oswald, Tobome, Sèmèvo Romaric, Amossou, Labissi Francois, Dossou, Francis, Barišić, Tatjana, Boras, Miran, Brekalo, Zdrinko, Blagojević, Ivana Čuljak, Damjanović, Ana, Dragisic, Vedran, Šimić, Ana Dugandžić, Gunaric, Filip, Kajic, Martin, Knežević, Darko, Krešić, Tanja, Lasić, Valentina, Letica, Ludvig, Martinovic, Vlatka, Mikulic, Iva, Miskovic, Josip, Pehar, Hrvoje, Rastović, Pejana, Sesar, Irena, Šetka‐čuljak, Violeta, Soljic, Martina, Tiric, Dejan, Tomić, Vajdana, Vasilj, Anja, Hudic, Igor, Oliver, Renato Aguera, Lamonica, Felipe Azenha, De Medeiros, Jorge, Florindo, Henrique Donizetti Bianchi, Filho, Rodolfo Jose Favaretto, Pereira, Fernanda Costa, Rodrigues, Rodrigo, Junior, Antonio Antunes Rodrigues, Andrade, Fernanda Ruiz, Salvetti, Maisa, Campioto, Débora Schalge, Lamonica, Mayra Tuboi, Urbano, Gustavo, Prado, Ricardo Villela, Alonso, Nivaldo, Santos, Carlos Ferreira, Tonello, Cristiano, Pires, Robinson Esteves, Rezende, Ricardo Fernandes, Reis, Igor, Marson, Fernando Augusto Lima, Ferreira, Erick Pires, Palamim, Camila Vantini Capasso, Brandao, Marcelo, Souza, Tiago Henrique, Maunsell, Rebecca, Neto, Alfeu Accorsi, Accorsi, Guilherme, Fernandes, Murilo Francisco, Machareth, Camila, Moura, Barbara Viegas, Dias, Vanessa, Guarienti, Luciano, Sampaio, Lia Regina, Vendrame, Cristiano, Coelho, Tatiane Amorim, Becker, Karin, Dias, Andre, Fachin, Camila Girardi, Gomes‐da‐silva, Monica Maria, Moraes, Isabela, Pinto, Amanda, Stychnicki, Adriano Seikiti, Julio, Nathalia Siqueira, Santos, José Mauro, Junior, Humberto Fenner Lyra, Oliveira, João Carlos Costa, Onzi, Tiago Rafael, Gerber, Marlus Tavares, Coelho, Filipe Osni, Silva, Janaína Carla, Panis, Carolina, Rech, Daniel, Avelino, Melissa, Botacin, Lais, Gonçalves, Mateus Capuzzo, Santos Leite, Amanda Lira, Pol‐fachin, Laercio, Bezerra, Tainá Santos, Santos Junior Alcimar, Alcimar Lavareda, Amorim, Robson, Leão, Maria Eduarda Bellotti, Bergamasco, João José Corrêa, Pinheiro, Cintia Cardoso, Neto, Rubem Alves Da Silva, De Araújo, Elaine Francisca, Guimaraes, Lilian, Liborio‐kimura, Tatiana, Camara, Isabelle Melo, Siqueira, Victor Ripardo, Rodriguez, Juan, Silva, Jeancarllo, Junior, Rubem Alves Silva, Cardoso, Cláudio, Guimaraes, Andre, Alves, Wislene Sarajane Moreira, Menezes, Agna Soares Da Silva, Araujo, Marcelo, Brito, Kattiucy, Albuquerque, Josie Marcelle Lira, Dussan‐sarria, Jairo Alberto, Souza, Andressa, Stüker, Andre Ricardo, Bresciani, Tiago, Stefani, Luciana Cadore, Cavazzola, Leandro Totti, Costa, Tainá, Dasqueve, Matheus, Marangon, Gustavo De Bacco, Martins, Otávio Ritter Silveira, Rodrigues, Josy, Cardoso, Guilherme Roloff, Neto, Brasil Silva, Soares, Tilaê, Zanella, Aline, Filippi, Lucas Torelly, Guerra, Enilde Eloena, Cruz, Ricardo Pedrini, Kalil, Antonio Nocchi, Laporte, Gustavo, Salem, Moacyr, Lima Brazan, Murilo, Campos Prado, Caio Antonio, Moises, Elaine Christine Dantas, Suto, Hilda Satie, Yasuda, Alice Gadotti, Zani, Ana Carolina Tagliatti, Santos, Roberto Cardoso Cardoso, Duarte, Geraldo, Joviliano, Edwaldo Edner, Santos, Carolina Lourenço Gomes, Quintana, Silvana Maria, Tamashiro, Edwin, Valera, Fabiana Cardoso Pereira, Zaccaro, Marília Veccechi Bijos, Andreotti, Isis, Lima, Leonardo, Salgado, Wilson, Cunha Viana Júnior, Alonço, Moutinho, Lana, Oliveira, Cora Pichler, Martins, Isabela Trindade, Toledo, Isabela Vieira, Guimaraes‐filho, Marco Antonio Correa, Arrivabeno, Rodrigo, Murta, Claudio Bovolenta, Said, Danniel Frade, Junior, Jose Pontes, Pugliesi, Felipe Guimarães, Gregorio, Paulo, Mariani, Alessandro, Minamoto, Fabio, Silva, Juliana Lourenço, Muller, Bruno, Zanon, Caio, Carvalho, Vladimir C., Lima, Ana Lucia Munhoz, Oliveira, Priscila R, Santos Silva, Jorge, Teixeira, Mariana Faccini, Kulcsar, Marco, Matos, Leandro, Nunes, Kamilla Schmitz, Junior, Joel Abdala, Abdallah, Emne, Carvalho, Genival Barbosa, Farias, Igor Correia, Silva, Cassia, Eloi Pinto, Fabio Fernando, Facure, Luciana, Godoy, André, Kupper, Bruna, Leite, Fernanda, Melo Lôbo, Matheus, Mantoan, Henrique, Marques, Narimã, Marques, Tomas, Medici, João Paulo, Torres, Silvio Melo, Garcia, Katheryne Merlos, Meduna, Rafael Ribeiro, Herbst, Ana Carolina Scintini, Santos, Silvana Soares Dos, Gonçalves, Bruna Tirapelli, Antonini, Marcelo, Brienze, Carolina, Farah, José Francisco, Gonçalves, Rodrigo, Machado, Vinicius, Nadal, Luis Roberto, Rodrigues, Danilo Nadal, Pansani, Adrieli, Rocha, Maria Luiza, Simonsen, Marcelo, Tsuchiya, Daniela, Vasques, Rafaela, Amorim, Jorge, Carvalho, Ana Alyra, Correia, Rebeca, Santos, Brena Costa, Neto, Henrique Jorge Guedes, Nakano, Luis, Pereda, Mariana, Vasconcelos, Vladimir, Awada, Jamile Barakat, Gava, Guilherme, Ijichi, Tiago Riuji, Kim, Nam Jin, Nunes, Rafael, Pinto, Fabio, Pereira, Thiago Henrique Sigoli, Volpe, Gustavo Jardim, Gatti, Arthur, Nardi, Caroline, Oliva, Ramon, Oliveira, Layze Braz, Carvalho, Herica Emilia Félix, Ribeiro, Ivonizete Pires, Rodrigues, Gabriel Renan Soares, Sousa, álvaro Francisco Lopes, Chebel, Michel, Sousa Fernandes, Paulo Henrique, Freitas, Marcelo Augusto Faria, Cunha, Juliano Rodrigues, Ather, Zeenia, Dimitrov, Dobromir, Filipov, Emil, Gyokova, Elitsa, Ilieva, Ivelina, Ivanov, Tsvetomir, Karamanliev, Martin, Neykov, Vasil, Atanasov, Boyko, Belev, Nikolay, Kamenova, Paolina, Tonev, Kaloyan, Yotsov, Tsanko, Hristova, Evguenia, Spassov, Kolyo, Tsankov, Tsanko, Dardanov, Dragomir, Gribnev, Petar, Sokolov, Manol, Brown, James, Tanyi, John, Hurdle, Heather, Maclean, Anthony, Sander, Michael, Al Riyami, Salim, Bali, Krittika, Bigam, David, Dajani, Khaled, Anvari, Mehran, Bolis, Rafik, Choi, David, Ellis, Susan, Gupta, Michael, Hanna, Wael, Hong, Dennis, Horner, Cynthia, Luketic, Lea, Moisiuk, Peter, Shargall, Yaron, Alfaro, Hilda, Alkhamesi, Nawar, Allen, Laura, Brackstone, Muriel, Chan, Eunice, Cheng, Davy, Chui, Jason, Gonzalez, Nelson, Lanting, Brent, Macneil, S. Danielle, Mayer, Robert, Mcgee, Jacob, Nagappa, Mahesh, Power, Nicholas, Prempeh, Agya, Qiabi, Mehdi, Razvi, Hassan, Schemitsch, Emil, Sehmbi, Herman, Shah, Ushma, Subramani, Yamini, Vasarhelyi, Edward, Vogt, Kelly, Yang, Homer, Abdehgah, Ali Ghorbani, Balvardi, Saba, Feldman, Liane, Fiore, Julio Flavio, Hanson, Melissa, Hopkins, Brent, Kaneva, Pepa, Lee, Lawrence, Leonard, Julia, Abou‐khalil, Jad, Martel, Andre, Stevenson, James, Lee, Susan, Merchant, Richard, Avoine, Samuel, Belanger, Laurence, Belanger, Mathieu, Belzile, Etienne, Blais, Anne‐sophie, Boucher‐kovalik, Sofia, Boulanger‐gobeil, Cindy, Cardinal, Etienne, Champagne, Pierre‐olivier, Cloutier, Jonathan, Corriveau‐durand, Simon, Cote, Mathieu, Cote, Maxime, Côté, Mathilde, Courval, Valérie, Demers, Suzanne, Desbiens, Christine, El Ouazzani, Mehdi, Girard, Karine, Girard, Ève‐marie, Gosselin, Karo, Khuong, Helene, Labrecque, Nathalie, Langlais, Eve‐lyne, Larouche, Audrey, Lavallée, Andréane, Lemyre, Madeleine, Maheux‐lacroix, Sarah, Marien, Melissa, Marin, Patrick, Mauger, Julie, Milot, Genevieve, Nadeau, Sylvie, Nguyen, Sebastien, Paris, Mélinda, Pelet, Stéphane, Plante, Marie, Plante, Carole, Pouliot, Frederic, Renaud, Marie Claude, Sarlabous, Mathilde, Schmit, Isabelle, St‐germain, Raphaël, Johnston, Brian, Labine, Nicole, Persad, Amit, Pham, Hong, Wood, Melissa, Azam, Riordan, Atrey, Amit, Beckett, Andrew, Cohen, Daniel, Das, Sunit, Daza, Julian, Dunkerton, Cheryl, Ellenbogen, Yosef, Hanley, Ciara, Kellett, Sorcha, Khoshbin, Amir, Ladha, Karim, Mcfarlan, Amanda, Montgomery, Spencer, Pazmino‐canizares, Janneth, Suresh, Hrishikesh, Vasdev, Ravleen, Ahmed, Maira, Gentili, Fred, Kalyvas, Aristotelis, Millesi, Matthias, Sarica, Can, Shaikh, Taariq, Leslie, St, Jacques, Null, Tabasinejad, Raha, Zadeh, Gelareh, Hsiao, Marvin, Jedrzejko, Nicole, Black, Peter, Broe, Claire, Dandurand, Charlotte, Grey, Rebecca, Leung, Philemon, Lindberg, Andrew, Gutierrez, Juan Mata, Mayson, Kelly, Meneghetti, Adam, Phillips, Drew, Street, John, Calderón, Carolina Carvajal, Pizarro, Daniel Alejandro Donoso, Fernández, Esteban, Molero, Ángela, Mutarello, Nastassja, Lucic, Jorge Núñez, Gaete, Katherine Ochoa, Lopez, Catalina Ruiz, Sepúlveda, Rina, Ulloa, Camila, Barreda, Mauricio, Dallaserra, Matias, Wood, Matías Günther, Tobar, Mauricio Sandoval, Garcia‐huidobro, Francisco, Dona, Jimena, Diez, Carolina Soto, Igor, Daniel, Mena, Javier, Reyes, José Tomás, Soto, Catalina Arredondo, Campos, Jose, Gonzalez, Javier, Rivera, Barbara, Altamirano‐villarroel, Jaime, Cohn, David, Amesti, Luis Marin, Recabal, Pedro, Sandoval, Camilo, Fonseca, Bruno Catoia, Contador, Monica, Hodali, Andres, Pincheira, Camila, Mantilla, Andrea Ramos, Garrido, Claudio Salas, Torres, Janina, Valenzuela, Marco, Chen, Zehua, Jiankun, Hu, Tao, Jin, Yang, Kun, Zhang, Yuexin, Chen, Yuan, Cunchuan, Wang, Yang, Wah, Bai, Xueli, Liang, Tingbo, Tao, Ma, Ning, Pu, Yin, Hanlin, Caicedo, Camilo, Beltran, Diego Felipe Tellez, Escobar, Alejandro, Granados, Carolina Perez, Pinzon, Lisbeth Alexandra Urueña, Bonilla, Carlos, Santana, Diana, Serrano, Oscar, Garcia, Andrea, Luque, Fernando Giron, Patino‐jaramillo, Nasly G., Baquero, Laura Giselle Contreras, Botero, Nestor Augusto Muñoz, Castellanos, Jhoana Andrea Murillo, Calvera, Andrea Juliana Vega, Acosta Buitrago, Lina M., Bohórquez‐tarazona, Maria Paz, Rivera, Paulo Andrés Cabrera, Felipe Casas, J, Alfaro, Valeria Cormane, Corso, Julian, Guerra, Bayron, Guerrero‐becerra, Albert Franz, Abiyomaa, Akram Kadamani, Montes, Felix Ramon, Paz, Manuel Santiago Mosquera, Sandoval, Camilo Andrés Polanía, Quintana, Natalia, Ortega, Carlos Fernando Roman, Santacruz, Carlos, Téllez, Manuela, Sánchez, Camilo Alejandro Velandia, Arias‐amézquita, Fernando, Vargas, Luis Felipe Cabrera, Murgueitio, Natalia Cortes, Escorcia, Elkin, Ghotme, Kemel Ahmed Ghotme, Gomez‐mayorga, Jorge Luis, Vergel, Alvaro Felipe Guerrero, Herrera‐almario, Gabriel, Londono‐schimmer, Eduardo, Mejia, Juan A., Monsalve, Guillermo, Rodriguez, Camilo, Niño, Juan Nicolas Rodriguez, Ortegón, Luis Martín Rodríguez, Sanabria, Daniel, Alvarez, Andres, Andrade, Arnulfo, Ardila‐montealegre, Javier, Baquero, David, Vidales, Edgar Mauricio Barrios, Giraldo, María Alejandra Caicedo, Carvajal, María Camila, Castillo, Maria, Florez, Maria Carolina Castillo, Cendales, María Angelica, Monroy, Danny Conde, Cortes, Henry, Daniel, Mario, De la Peña, Jairo, Delgado‐nieto, Elena Leonor, Espitia, Hernando, Avendaño, Carlos Figueroa, Burgos, Edgar Oswaldo Hernandez, Isaza‐restrepo, Andres, Londono, German, Maldonado, Margarita Maria, Montenegro, Andrea, Navarro, Juan Carlos, Navarro‐alean, Jorge, Abaunza, Katherine Parra, Pulido, Eliana, Ramírez Amaya, Erika M., Chaves, Carlos Eduardo Rey, Rincón, Natalia Andrea Rivera, Castillo, William Mauricio Riveros, Sanchez, Lizeth Rodriguez, Rubiano, Wilson, Russi, Maria, Olarte, Juan Carlos Sabogal, Tovar, Javier Mauricio Salgado, Sanchez, Maria Juliana, Varela, David Mauricio Solano, Gomez, Paula Torres, Trillos, Marcial, Patiño, Ana María Vargas, Vargas‐barato, Felipe, Leon, Juan Pablo Villate, Useche, María Alejandra Wagner, Acosta, Jesus, Almeciga, Adriana, Mendez, Luis Becerra, Beltran, Rafael Jose, Bonilla, Ana, Buitrago, Miguel, Cabrera, Marino, Quiroz, Pedro Hernando Calderon, Camacho‐nieto, Diego, Fierro, Carlos Andrés Carvajal, Bonilla, Sergio Cervera, Diaz, Sandra, Facundo, Helena, Forero, Jorge, Mora, Mauricio Garcia, Tirado, Karena Victoria Garcia, Perez, German Fabian Godoy, Gonzalez, Felipe, Guevara, Oscar, Hernandez, Jairo Alonso, Mora, David Ricardo Herrera, Lalinde, Juan David, Lehmann, Carlos, Llanos, Eduardo Leon, Lopez, Byron Eduardo Lopez De Mesa, Mariño, Ivan, Medina, Monica, Morales, Raúl Eduardo Pinilla, Puerto, Angela, Null, Ma, Quintero‐ortíz, Andrea, Hernández, Juliana Rendón, Cortés, Elio Fabio Sánchez, Hernández, Alvaro Eduardo Sánchez, Suarez, Raul, Suescun, Oscar, Vanegas, Marco, Varela, Rodolfo, Bernal, Jorge Luis Velez, Viveros‐carreño, David, Gómez, Daniela Camargo, Fletcher, Angelica, Merchan, Abel, Luna, Euler Javier Burbano, Cujiño, Indira, Galvis, Mauricio Velasquez, Galliadi, Lina Maria Vergara, Gonzalez, Orlando Abonia Gonzalez Abonia, Saravia, Maria Fernanda Acuna, Arroyave, Roberto, Angulo, Jose Maria Barreto, Bonilla‐escobar, Francisco Javier, Cardona, Uriel, Giacometto, Ivan Castañeda, Castillo, José Luis, Castillo‐cobaleda, Diego Fernando, Garcia, Diego Jose Caycedo, Tello, Brenda Marcela Coll, Dueñas‐ramirez, Juan Carlos, Vidarte, Oscar Andres Escobar, Figueroa, Luis, Garcia‐perdomo, Herney, Gomez, Alden, Gomez, Laura, Gomez, Alejandro, Grande‐gil, Ana María, Guarin, David, Guzman, Natalia, Castañeda, Enrique Herrera, Hinaoui, Marisol, Escobar, Anuar Armando Idrobo, Kammerer, Christian Kammerer, Leon, Sergio, Lucero, Carlos Antonio Llanos, López, Angie, Martinez‐blanco, Alexander Maximiliano, Casella, Antonio José Montoya, Corredor, Ricardo Andres Niño, Ordoñez, Sebastian, Uribe, Diego Alfredo Palta, Serna, Andrea Carolina Perea, Ríos, July, Ríos‐samper, Gabriel, Garcia, Juan David Rivera, Moreno, Juan Camilo Salcedo, Sandoval, John, Ramirez, Guillermo Alberto Sarmiento, Romero, Paola Andrea Tabares, Urzola, Ricardo, Valdes‐duque, Iliana Maria, Velasquez, Miguel, Villegas, Lina Maria, Zapata‐copete, James, Lara, José Omar Zorrilla, Zuluaga, Mauricio Zuluaga, Moreno, Alejandra Echeverri, Figueroa, Juan Sebastian, Ortiz, Adolfo Enrique Gómez, Mosos, Maria Fernanda Gonzalez, González‐orozco, Alejandro, Roncancio, Juan Jose Jaramillo, Martínez, María Camila Leyva, Mosos, Monica, Ramirez, Juan Sebastian, Rodríguez, Henry Andrés, Henao, Juan David Saavedra, Varón, María Alejandra Torrado, Ramírez, Leidy Natalia Idarraga, Ocampo, Lorena, Marin, Monica Cardona, Gonzalez, Ana Maria Marin, Mejia, David Alejandro, Vanegas, Luis Emiro, Martinez, Yicel Alvarez, Vesga, Sandra Aruachan, Fuentes, Dayana Vanessa Baron, Salas, Alejandra Caballero, Estrada, Gustavo Antonio Martinez, Campo, Kelly Viloria, Alvarez, Juan Antonio Corralez, Regino, Cesar David Galindo, Velasquez, Angela Maria Giraldo, Moreno, Carlos Enrique Melo, Tejada, Jorman H., Tovar, Jesus Hernan, Tovar, German Alirio, Hernández, Edison Alexander Benavides, Orozco‐chamorro, Claudia Milena, Angel, Gustavo Adolfo, Buesaquillo, Christian Ali, Montaño, Victor David Olave, Sánchez‐gómez, Andrés, Ureche, Daniela Patricia Escalante, Garrido, Jairo Martinez, Genda, Eben‐ezer, Eboma, Fabrice, Bitunjac, Kristina, Grulović, Karlo, Vučković, Marijana, Šantak, Goran, Borovic, Emanuel, Versic, Ana Bosak, Hasandić, Damir, Grabar, Natasa Poldan, Medancic, Suzana Srsen, Brkic, Lucija, Cokarić, Sara, Palac, Petra Pavic, Samac, Zeljka, Tomić, Josipa, Vrdoljak, Marija, Bacic, Ivan, Bakmaz, Bernarda, Vučičić, Nikolina Bratošević, Brzic, Domagoj, Canovic, Samir, Dijan, Emilio, Dragicevic, Maja Grgec, Karlo, Robert, Konjevoda, Suzana, Kovačević, Petra, Kovačić, Ivan, Markulić, Frane, Matak, Luka, Morović, Domagoj, Perišić, Gordan, Simic, Andrea, Skitarelić, Neven, Veršić, Matea, Žufić, Vanja, Zuzul, Matea, Anzic, Srdan Ante, Carevic, Iva, Litvic, Dubravka Heli, Markov‐glavas, Duska, Jovanovic, Tatjana Savic, Augustin, Goran, Biloš, Jerko, Biočina, Bojan, Biosic, Vedrana, Bobovec, Dino, Botica, Iva, Bumber, Boris, Čerina, Petra, Vukovic, Katarina Duric, Gasparovic, Hrvoje, Gatin, Lucija, Grsic, Kresimir, Radojković, Ika Gugić, Jelčić, Ivan, Kastelan, Zeljko, Kolak, Juraj, Kulis, Tomislav, Kunjko, Kristian, Maric, Marjan, Kavanagh, Marcel Marjanović, Milicic, Borna, Morić, Trpimir, Pasini, Miram, Penezić, Luka, Prgomet, Drago, Prstacic, Ratko, Prtorić, Andreja, Radojković, Rudolf, Romić, Ivan, Sečan, Tomislav, Šoša, Dora škrljak, Slipac, Juraj, Tomic, Mislav, Zedelj, Jurica, Zekulić, Toni, Zimak, Zoran, Lorencin, Mia, Luksic, Ivica, Mamic, Matija, Espinsa, Norberto Miranda, Cruz, Ailén Sánchez, Antoniou, Stavros A., Kakas, Michael, Panayiotou, Yiannis, Almezghwi, Heyam, Arslan, Kalbim, Besim, Hasan, Özant, Ali, Özçay, Necdet, Kokkinos, Georgios, Papatheodorou, Panayiotis, Pozotou, Ioanna, Stavrinidou, Olga, Yiallourou, Anneza, Burda, Lukáš, Dosoudil, Michal, Martinek, Lubomir, Gawel, Wladyslaw B., Lerch, Milan, Peteja, Matúš, Žatecký, Jan, Daniel, Toman, Formánek, Martin, Javurkova, Veronika, Kepičová, Markéta, Macečková, Nicole, Matousek, Petr, Simetka, Ondrej, Vavra, Petr, Zelenik, Karol, Černý, Jan, Khan, Sami, Lischke, Robert, Přibyl, Martin, Younus, Temoore, Amarasena, Yenuksha, Klíma, Karel, Pirmorad, Setareh, Hotová, Zuzana, Mladěnka, Aleš, Bozo, Nulvin, Harbjerg, Julie Lykke, Hviid, Louise, Kristensen, Helle ø, Mekhael, Mira, Nielsen, Mette Fugleberg, Paulsen, Laerke, Sinimäki, Saija, Mogensen, Louise Zinck, Bonde, Peter, Ebbehøj, Anders Lyng, Fenger, Anne‐sophie, Haugstvedt, Aleksander Fjeld, Hansen, Christine Hangaard, Jönsson, Maria Lovisa, Jorgensen, Lars N, Krarup, Peter‐martin, Lihn, Anne‐louise, Meyhoff, Christian, Otte, Helena, Amar, Anas Ould Si, Palm, Henrik, Schlesinger, Nis, Smith, Henry, Tryggedsson, Ida, Axelsen, Anne Reiss, Bælum, Jens Kristian, Ellebaek, Mark Bremholm, Ellebæk, Signe Bremholm, Hogh, Anders, Acosta, Maria, Acosta, Yancy, Baez, Pedro, Betances, Luis Alfredo, Bonilla, Luis Rodolfo, Cabreja, Daniel, Cruz, Wilton Cabrera, Expósito, María Mabel Collado, Crespo, Aldo, Cruz‐pineda, Octavio, D’óleo García, Claudio Samuel, Díaz, Pedro, Escoto, Remberto, Figueroa, Jatnna, Garcia, Luis, Rodriguez, U Garcia‐Dubus, Gomez, Humberto, Grullon, Adrian, Guerrero, Fatherin, Guzman, Lillian, Mosquea, Thelma Rocío Jiménez, Lazala, Engels, Lopez, Ariela, Francisco, Leeany Maletta, Mercado, Jhomayri, Munoz, Herisardy, Paulino, Jeffrey, Fernandez, Maricely Ambar Perez, Reyes, Rudeily, Guilamo, Lilia Rosa Reyes, Rivas, Ruben, Torres, Claudia Alejandra Rivas, Rodríguez, Ada, Villa, Madelin Tamar Rosario, Santana, Eleazar, Soto, Joel, Tactuk, Nassin, Sardiñas, Cristina Kristel Tonos, Ubinas, Raul, Victoria, Jose, Villegas, Aaron, Acra‐tolari, Ricardo, Beltran, Larissa, Betances, Luis Fernand, Blaubach, Alejandro, Mejía, Denisse Idalia Campos, Capellan, Nathalia, Bruzual, María Fernanda Cedeño, Spencer, Saray Cordero, Lantigua, Gabriella Cuevas, De Jesus, Luis, Díaz, Gabriela, Vásquez, Pedro Pablo Díaz, Disla, Karla, Uceta, Jesús Antonio Echavarría, Jimenez, Paola Irina Eusebio, Fernandez, Damaris, Camilo, Marlin Fernandez, Germosen, Jiomar Manuel Figueroa, Fortunato, Maruel, Fernández, Leyla Gabriel, Dihmes, Alicia German, Herrera, Héctor, Cuevas, Elizabeth Leon, Mata, Jose Alejandro, De La Cruz, Mirian Mateo, De la Cruz, Dolores Mejia, Mirambeaux, Marcos, De La Cruz, Fabio Ortiz, Paulino, Henry, Pelletier, Gabriela, Pichardo, Merycarla, Enrique, Rodriguez Pumarol Próspero, Rivas, Julio, Marmolejos, Ann Stephany Sanchez, Santana, Roman Santana, Almanzar, Irina Suero, Sánchez, María Magdalena Vásquez, Campuzano, Nicolás, Ocampo, José Ricardo Negrete, Armas, Maria, Guerra, Alvaro Santiago LeMarie, Vizcaya, Gustavo León, Abdelwahab, Omar Ahmed, Elmehrath, Ahmed O., Mostafa, Mohammed Ezzat, Amira, Gamal, Sallam, Ibrahim, Sherief, Mohamed, Abdelmajeed, Ahmed, Abdou, Mostafa, Shanab, Ahmed Abo, Abodeeb, Aya, Aboelkhel, Roger, Abosamak, Nour Eldin, Bakr, Amna Abou, Aboubakr, Samar, Abouelnagah, Yossof, Aboumadawy, Omar, Adel, Dina, Afifi, Nermeen, Ahmed, Sara, Ahmed, Abedelrahman, Sayed, Mohamed AL, Alberkamy, Abdelrahman, Aldahma, Mohamed, Ali, Ahmed, Ali, Mostafa, Bakr, Mohamed Amin, Anter, Alaa, Asal, Doaa, Ashoush, Fouad, Ashraf, Olfat, Ashraf, Abdel Rahman, Atta, Rewan, Badr, Salma, Bahaaeldin, Mohamed, Bastawesy, Mostafa, Darwish, Sara, El Kharashy, Rasha, Elassar, Ziad, Elbadawy, Seifeldin, Elkhity, Dina, Elsaka, Alromisaa, Elsayed, Manal, Hewalla, Mostafa Elsayed Elsayed, Elshafey, Mohamed, Eshac, Youssof, Eshac, Fares, Essameldin, Amr, Ewedah, Moataz, Ezz, Yara, Farag, Mohamed, Gadelkarim, Inas, Gadelrab, Ziyad, Gamal, Dina, Ghaly, Mira, Girgis, Nathalie, Gouda, Omar, El Goweini, Nancy H., Hafez, Nour, Hafez, Youssef, Abdin, Abdelkader Hamed, Hanno, Rodina, Hassanin, Aliaa, Hassanin, Mohamed, Hemead, Hanan M., Hemida, Abdelrahman, Hosain, Maher, Hossam, Ahmed, Aly, Hamza Hussein Aly Salama, Ibrahim, Mohamed, Ibrahim, Abdelrahman, Ibrahim, Nourhan, Hamouda, Noha Mohamed Salah Ibrahim Moussa, Iskander, Monica, Khalifa, Islam, Kotb, Mostafa, Mahmoud, Nada, Shabana, Alaa Mahmoud Abo, Mamdouh, Nora, Metwalli, Maram, Metwally, Khaled, Moghazy, Mahmoud, Mohamed, Moustafa, Mourad, Mohamed, Moustafa, Esraa, Mubarek, Kamilia, Nader, Nour Eldin, Nasser, Ahmed, Omar, Samaa, Qatora, Mostafa Shehata, Ragab, Mohamed, Ragal, Marawan, Ramadan, Dina, Ramadan, Rana, Ramadan, Sara, Romany, John, Sabry, Ahmed, Said, Yasmeen, Salamah, Sara, Saleh, Ahmed Mostafa, Elkaffas, Mona Saleh Mesbah Mohamed, Salem, Alaa, Salim, Hashem, Samih, Ahmed, Abdelaal, Ahmed Samir, Shaheen, Ahmed, Mohammed, Yassmeen Sharafeldin, Shehata, Abdelrahman, Shemeis, Mohamed, Shenit, Karim, Sheta, Mennatallah, Soffar, Asmaa, Tanas, Yousef, Tarek, Ahmed, Yehia, Nermin, Eid, Omar Khaled Mohamed, Abdulfattah, Ammar Yasser, Elsaghir, Ahmed, Elganainy, Mohamed Fouad, Elsayed, Omar Ibrahim, Elmandouh, Omar, Hamam, Omar, Shehata, Mostafa Ahmed, Abdelaziz, Areej A., Abbas, Ahmed M., El‐ghani, Wael Abd, Abd Elazeem, Hossam Aldein S., Elsayed, Mustafa Abd, Abd‐elkariem, Ahmed Yassien, Abdalla, Shimaa, Abdel‐aleem, Mahmoud, Abdelazeem, Khaled, Abdelfattah, Mahmoud, Abdelhafez, Mohammed, Abdelkarem, Mohamed M., Abdelraouf, Ali, Abdullaha, Lamess, Abubeih, Hossam, Ahmed, Moaiad Eldin, Ahmed, Nagm Eldin Abu Elnga, Ahmed, Ahmed, Saad, Sarah Ahmed, Alaa, Sherif, Alhussaini, Ali, Ali, Abdelrahman Ahmed Abdelrahman, Ali, Ibrahim, Ali, Wagdi, Mohamed, Mohamed Ali, Ashraf, Mohamed, Bassiouni, Muhammad, El‐adawy, Mohamed G., El‐sharkawi, Mohammad, Elkhayat, Hussein, Elmaghraby, Khaled, Elsdfy, Shady, Elsharkawy, Mohamed, Eltayeb, Almoutaz, Mohamed, Mohamed Esmat, Essam, Esraa, Fahd, Mahmoud, Farouk, Osama, Gadelkareem, Rabea, Ghoneim, Ahmed, Takrouney, Mohammed Hamada, Hamdan, Ahmed, Hamed, Abd El‐Rahman, Hasan, Ahmad, Hassanin, Mohamed Abdelghafor, Hawal, Islam, Henes, Kerollos, Herdan, Mohamed Omar, Hetta, Helal F., Ibrahem, Omar, Ibrahim, Mostafa, Ibrahim, Islam H., Kamel, Mahmoud, Khallaf, Mohamed, Elghazaly, Shrouk M., Mahfouz, Abobakr, Mahmoud, Osman, Mahran, Wesam, Mahrous, Doha, Marsis, Abadeer, Mohamed, Ayman, Hussein, Aliae Mohamed, Sayed, Amr Mohamed, Mohammed, Mahmoud M, Mokhtar, Ahmed, Monib, Fatma A., Nageeb, Ahmed, Nageh, Mariam Albatoul, Nageh, Mohammed, Omar, Nehal Gamal, Ragab, Abdelrahman, Ramadan, Abdelrahman, Temerik, Abdallah Rashad, Sabry, Aya, Safwat, Hadeer, Salah, Omar, Mahmoud, Ahmed Elhussiny Salah, Saleh, Ahmed, Sallam, Mahmoud, Samir, Ahmed, Sayad, Reem, Sayed, Esraa, Sedik, Ahmed S., Shahine, Mohammed, Soliman, Antonios, Soliman, Wael, Taher, Mohamed Gamal, Wanees, Randa, Yousof, Ebrahim Ahmed, Youssef, Ahmed, Elabedeen, Omar Zein, Hassan, Ahmed Emad Sayed, Fattah, Shrouk Abdel, Abostate, Ahmed, Ali, Samar, Salama, Saad Ali Saad, Allam, Mohamed, Alsadek, Ahmed, Arafa, Ebrahim, Barakat, Ahmed, El Sherpiny, Mohammed, Elbehairy, Gehad, Eleisawy, Mahmoud, Elgendy, Abdelrahman, Elhawary, Rewan, Eltregy, Sherif, Hamdy, Mahmoud, Hassan, Gehad, Khalifa, Aya, Mahmoud, Ahmed, Altukhy, Ahmed Mohamed, Noah, Kareem, Noureldin, Yasser, Nowar, Mostafa, Saad, Moustafa, Elsaeidy, Ahmed Saad, Elsaeidy, Khaled Saad, Sabry, Hesham, Sameh, Mostafa, Said‐elnaby, Ahmed Tarek, Zahed, Mohamed, Zahran, Mohamed, Zaid, Abdelrahman, Zoghary, Ahmed Zaki, Atef, Mohamed, Mohamed, Ahmed, Youssef, Mohamed, Abdelhamid, Mahmoud Hossameldin Saad, Alazab, Emad, Awad, Ahmed K., Darwesh, Amr, El Fiky, Lobna, Elgarhy, Ibrahim, Nassef, Mohamed Adel, Shaban, Mahmoud, Shalaby, Mahmoud Mohamed Mohamed, Wahba, Abdelrahman, Fouad, Omar Youssif Omar, Elsadek, Menan, Gad, Dalia, Abdelsamed, Ahmed, Bayomy, Abdulhakeem, Elsalhy, Mohamed, Fahim, Ahmed, Seleim, Ahmed, Afifi, Eman, Gamal, Fatma Alzahraa, Gamal, Mennatullah, Eldesouky, Omnia, Eldwini, Mohamed Hatem Elmetwalli Eldwini, Fahmy, Mostafa Medhat Fahmy, Hussein, Ahmed, Ouf, Abdallah, Sami, Omar, Shaat, Salem, Bahi, Abdullah Wael Mostafa Khalil, Atea, Abdurhman, Gamal, Ibrahim, El Kassas, Mohamed, Omar, Wael, Tawheed, Ahmed, Al‐oribi, Saeid, Aly, Nuran Khaled, Elfiky, Mahmoud, Elmaghraby, Alaa Eldine, Elrahmany, Abdulrahman, Elsherbeeny, Motaz, Helmy, Youssef, Nabil, Ahmed, Farahat, Ahmed Samir, Soliman, Mostafa, Wassef, Amr, Abdelrahman, Abdelrahman, Elsaban, Seif, Ghaly, Galal, Hamdy, Rana, Mondy, Hamada, Abdallah, Lubna, Darwish, Abdelrhman KZ, Rabea, Mohamed, Azab, Mohammed A, Abbas, Alzhraa Salah, El‐deeb, Marwa, Fawzy, Mohamed, Ibraheem, Maher, Bakry, Abdelrahman, Elnems, Sarah, Elsheikh, Randa, Gbreel, Mohamed Ibrahim, Hafez, Mahmoud, Jammal, Mohamed, Hamam, Khaled M, Makram, Abdelrahman M, Makram, Omar Mohamed, Rabie, Salma, Askalany, Sherine Yousery, Abushanab, Mokhtar Mohamed Ibrahim, Eid, Abdulrahman, El Ghalid, Mohammed Refaat Ibrahiem Amin, Abdelaty, Ahmed Adel, Fayad, Elsayed A., Radwan, Asmaa, Sallam, Moataz, Shokry, Ahmad, Farouk, Ahmed Mohamed, Elfallal, Ahmed, Elfeki, Hossam, Elsaeed, Mohamed, Elsaid, Mahmoud, Makroum, Amany, Elsaid, Dina Mohamed, Mostafa, Mohamed, Omar, Mohamed W, Rezk, Mohamed, Sakr, Ahmed, Sanad, Aly, Shalaby, Mostafa, Shawqy, Mohammed, Shetiwy, Mohamed, Shoma, Ashraf, Tawakl, Noura, Yunes, Asmaa, Abouzid, Amr, Atallah, Khalid, Elmorsi, Rami, Elsherbini, Ahmed, Gaballa, Khaled, Hamdy, Omar, Hamdy, Mohamed, Metwally, Islam Hany, Refky, Basel, Shetiwy, Mosab, Zuhdy, Mohammed, Zahran, Mohammed A, Abdellah, Fatima, Abdelmawla, Ahmed, Abdrabou, Ahmed, Abubakr, Asmaa, Al Gohary, Rawda, Al‐shazly, Mohammed Hamdy, Ali, Mohamed, Allam, Abdallah R, Aposaeeda, Aya, Asfour, Mohammed, Ayman, Ammar, Omran, Abdelrahman Azzam, Daghash, Ibrahim Tawfiq, Ebada, Mahmoud Ahmed, Eid, Taher, El Kelany, Ahmed, El Shemy, Esraa, El‐hag‐aly, Mohammed, Elgamal, Omar, Elghoury, Mahmoud, Elkased, Ahmed Farag, Ellakwa, Takwa Hamed, Ellakwa, Hamed, Elmeanawy, Amr, Elnoamany, Salma, Elsabagh, Alaa, Elsawey, Abdelrahman, Elshabrawy, Enas, Elshakhs, Seliman, Elsoudy, Naira, Ezzat, Esraa, Fawzy, Ahmed, Gamal, Abrar, Gameel, Ahmed, Gharbia, Khaled, Ghonaim, Mohamed, Ghonaim, Alaa, Hafez, Ahmed, Hafez, Abdelrahman, Ismail, Zainab, Khaled, Mohamed, Meselhy, Mohammed, Mikhail, Pola, Mohamed, Mervat, Mougahed, Mohamed, Mustafa, Abdulla, Nada, Ahmed, Omran, Janna, Ebiad, Mohamed S., Saleh, Ibrahiem, Salem, Nourhan, Salem, Osama, Selim, Salma, Shalaby, Ghada, Sherif, Hoda, Soltan, Hatem, Wahbah, Mahmoud, Abdelbary, Eman Zakaria, Zayan, Ahmad Helmy, Afify, Abdelrahman, Hadiya, Hossam Ali, Elshref, Mohamed Jamal, Ahmed, Mostafa Mohamed, Nasser, Nourhan, Abdeldayem, Hesham, Salama, Ibrahim Abdelkader, Ammar, Khaled, Ayoub, Islam, Aziz, Amr, Badawy, Mohammad Taha, Balabel, Mohamed, Fayed, Yahya, Gad, Emad Hamdy, Gomaha, Maher, Hammad, Essam, Hegazy, Osama, Hegazy, Elsayed, Ibrahim, Tarek, Kallaf, Mostafa, Macshut, Mahmoud, Magdy, Ammar, Oteem, Ahmed, Sallam, Ahmed, Samaan, Samy, Sharshar, Mohamed, Shoreem, Hany, Soliman, Elsayed, Soliman, Hossam Eldeen, Yassein, Taha, Zakaria, Hazem, Eldaly, Abdullah, Mashaly, Sarah, Abd‐elsalam, Sherief, Abdel‐elsalam, Wafaa, Shaalah, Ahmed Abdullah, Elbahnasawy, Mohamed, Elhalaby, Ismael, Hamada, Mohamed, Soliman, Sarah Hamdy, Hawila, Ahmed, Morsy, Mohamed Sherif, Naieem, Mohmed, Nasreddin, Mohammed, Salman, Samar, Sarsik, Sameh, Shabana, Ahmed, Tolba, Engy, Zagho, Mohamed, Kams, Liisa, Rätsep, Tõnu, Riips, Karolin, Abdurehman, Oumer, Admasu, Azarias, Berhea, Ataklitie, Eado, Yegeremu, Hailu, Nebiyou, Kidane, Meklit, Mohammed, Abdurezak, Mohammed, Khalid, Tibelt, Admasu, Woldemariam, Mersha Abebe, Yonael, Lydya, Alemu, Megersa, Aklilu, Abenezer Tirsit, Asele, Frehun, Assefa, Solomon, Azmach, Dawit, Bekele, Philimon, Mamo, Mickyas, Maru, Nahom, Mekuria, Haile, Menkir, Abel, Mikru, Filagot, Siraw, Eyerusalem, Suga, Hilkiah, Sumoro, Natnael, Teka, Aklilu, Thomas, Efeson, Woldemariam, Dereje, Wubishet, Estifanos, Abebe, Engida, Abebe, Kirubel, Asfaw, Fitsum, Bergene, Eyerusalem, Eshete, Mahder, Gebrehiwot, Fitsum Gebreegziabher, Gedefaw, Yetsedaw, Mengesha, Mulualem Wondafrash, Mengiste, Netsanet, Menjeta, Abeje, Muleta, Mahteme Bekele, Sefera, Sena, Tedla, Yonatan, Teklu, Daniel, Teshome, Henok, Tirfe, Leake, Tsegabrhan, Sahle, Tsehaye, Milkias, Worku, Bereket, Molla, Million, Supha, Melka, Taye, Tewodros, Abebe, Nebyou, Alemu, Berhanu, Chanie, Abera, Degefu, Hailegebriel, Desalegn, Dawit, Gebre, Hiwot, Hussen, Husnia, Kassa, Dawit, Laeke, Tsegazeab, Mammo, Tihitena Negussie, Negash, Samuel, Sahlu, Abat, Tiruneh, Abraham Genetu, Wolde, Amanuel, Woldeselassie, Hanna Getachew, Ahmed, Mnewer Y., Zewdneh, Betelhem, Fentaw, Jibril, Salia, Shemsedin, Tabore, Ketema, Gurara, Addisalem, Abreha, Tassew, Abrha, Teklebirhan, Beyene, Gaym, Hailu, Niguse, Weldu, Mulu Atsbaha, Abdissa, Desalegn, Tesfaw, Mequannet, Wolle, Melatework, Asmamaw, Dawit, Assefa, Biniam Zemedu, Bedane, Dereje, Bekele, Ephrem, Getie, Aderaw, Melkamu, Solomon, Mengesha, Workineh, Shumye, Getachew, Tagele, Gashaye, Tesfa, Abrham Amare, Workneh, Wubshet, Genetu, Sileshi, Mebratu, Eneyew, Chanyalew, Lidya, Deresse, Tilahun, Girma, Adissu, Seid, Marta, Shimelash, Dagim, Shitaw, Abrham, Ayalew, Tewabe, Diress, Tesfaye, Kassahun, Berhanu, Kassaye, Bersabeh, Mulugeta, Esubalew, Tesfaw, Getasew, Yimenu, Beminet, Benecha, Semir, Aman, Mudesir, Ibrahim, Adem, Mekete, Alem, Tesemma, Abdi, Mohammed, Adnan Abdulkadir, Abdullahi, Yasir Younis, Adem, Ephrem, Ahmedin, Mahlet, Assefa, Yared, Ayde, Fitsum, Berhe, Alazar, Gebremeskel, Zersenay, Siyoum, Eneyew Getachew, Teresa, Sintayehu, Wude, Zinaye, Yemer, Fasika, Yohannes, Dagnachew, Zeleke, Ewunetu, Zerihun, Gulilat, Degefe, Derje Worku, Derilo, Hankore Tamirat, Eliyas, Nebiyu, Bayissa, Firew, Deressa, Yadani, Gemechu, Lidya, Gurmu, Tegenu, Kasaye, Ashenafi, Melese, Lemi, Muleta, Lemesa, Mulugeta, Gersam, Taye, Seifu, Teshome, Abraham, Tesso, Birhanu, Gebrekirstos, Gebreagziabher, Haile, Mhreteab, Kassa, Haftamu, Saddik, Mohammed, Mengist, Alemneh, Heikkinen, Juuso, Helminen, Olli, Huhta, Heikki, Kotkavaara, Tommi, Mosorin, Matti‐aleksi, Pitkänen, Joel, Qian, Cheng, Sinikumpu, Jaakko, Sova, Henri, Tastula, Mikko, Virta, Ville P, Bettoni, Jérémie, Dakpé, Stéphanie, Devauchelle, Bernard, Lavagen, Nolwenn, Bastard, François, Bin, Kim, Breheret, Renaud, Fouquet, Olivier, Gueutier, Alexandre, Henric, Nicolas, Kahn, Alexis, Kün‐darbois, Jean‐daniel, Moukoko, Didier, Pineau, Anna, Podevin, Guillaume, Schmitt, Françoise, Alshawared, Fadi, Beyrne, Carlos Daniel, Lugans, Laurene, Marie‐macron, Lysa, Doussot, Alexandre, Ahmed, Omar, Alnajjar, Louy, Mis, Tommaso Cipolat, Fliss, Souha, Giocanti‐auregan, Audrey, Gregory, Thomas, Guiraudet, Patrice, Le Fouler, Adrien, Martinod, Emmanuel, Onorati, Ilaria, Peretti, Marine, Quilichini, Julien, Radu, Dana, Trésallet, Tresallet, Andro, Christophe, Maffert, Alexis, Chapman, Tracy, Halden, Maxime, Fayon, Julie, Mattevi, Catherine, Marion, Herjean, Bendjemar, Lynda, Lionel, Charre, Mikhael, Elie, Macías, Rosa Montero, Villefranque, Vincent, Volpin, Enrico, Trilling, Bertrand, Boleslawski, Emmanuel, Constance, Houlzé‐laroye, Drubay, Vincent, El Amrani, Mehdi, Eveno, Clarisse, Lecolle, Katia, Martin, Louis, Noiret, Barbara, Piessen, Guillaume, Truant, Stephanie, Zerbib, Philippe, Aubry, Estelle, Denimal, Franck, Lamblin, Antoine, Barrat, Benjamin, Caire, François, Christou, Niki, Fourcade, Laurent, Laloze, Jerome, Bouv‐hez, Margaux Mekann, Salle, Henri, Taibi, Abdelkader, Tricard, Jeremy, Usseglio, Julie, Chopinet, Sophie, Gregoire, Emilie, Delpont, Marion, Blanchard, Claire, Crenn, Vincent, Vergie, Stéphane, Denis, Waast, Fragnaud, Henri, Regenet, Nicolas, Rigaud, Jerome, Varenne, Yoann, Anract, Philippe, Barat, Maxime, Biau, David, Dautry, Raphaël, Dohan, Anthony, Idier, Louis, Lang, Elena, Thouny, Camille, Tzedakis, Stylianos, Audenet, François, Cazelles, Antoine, Chamouni, Alexandre, Karoui, Mehdi, Mejean, Arnaud, Clermidi, Pauline, Langlais, Tristan, Leonelli, Lorenzo, Maisonneuve, Emeline, Nicolas, Beaud, Perrot, Ophelie, Prost, Doriane, Thomin, Anne, Thouement, Thouement, Athiel, Yoann, Berry, Richard, Boddaert, Guillaume, Bonnet, Stéphane, Cathala, Nathalie, Conso, Christel, Denet, Christine, Laforest, Anaïs, Levy‐zauberman, Yael, Macek, Petr, Mombet, Annick, Ollat, Didier, Scamporlino, Adriana, Zadegan, Frederic, Amine, Chamakhi Ahmed, Baratte, Baratte, Chartier‐kastler, Emmanuel, Chereau, Nathalie, Colas, Pierre‐antoine, Duquesne, Igor, Genser, Laurent, Petit, Gaëlle Godiris, Goumard, Claire, Hasani, Ariola, Lim, Chetana, Martellotto, Sophie, Melot, Charlotte, Menegaux, Fabrice, Pinar, Ugo, Pocard, Marc, Roupret, Morgan, Scatton, Olivier, Seisen, Thomas, Séverine, Noullet, Turco, Célia, Chouillard, Elie, Beganton, Paul, Frasca, Denis, Kerforne, Thomas, Corbiere, Lisa, Gasmi, Anis, Ghemame, Marwane, Guérin, Sonia, Khene, Zine‐eddine, Livin, Marie, Mahmoud, Fedy, Maillot, Betty, Merdrignac, Aude, Mouriaux, Frederic, Robin, Fabien, Sulpice, Laurent, Vazeux, Charles, Bertheuil, Nicolas, Bonneau, Soline, Cazemajou, Clément Thierry, Cousin, Ianis, Defert, Coralie, Fustec, Elisa, Juricic, Melodie, Lavoue, Vincent, Mevel, Gwenaël, Timoh, Krystel Nyangoh, Renault, Annaëlle, Violas, Philippe, Schwarz, Lilian, Tuech, Jean Jacques, Morichau‐beauchant, Tristan, Sauvat, Frederique, Haddad, Elie, Vermersch, Sophie, Patrizi, Andrea, Roux, Alexia, Aimé, Adeline, Malgras, Brice, Cherkaoui, Zineb, D’Urso, Antonio, Felli, Emanuele, Gonzalez, Cristians Alejandro, Ignat, Mihaela, Mutter, Didier, Pessaux, Patrick, Vix, Michel, Gornes, Hugo, Vergriete, Kélig, Berthoumieu, Pierre, Genre, Ludivine, Le Gall, Hélène, Pierre, Trocard, Chalhoub, Marc, Del, Mathilde, Martinez, Alejandra, Fuchs‐buder, Thomas, Vancon, Antoine, Faya, Camara Abraham, Asaph, Elvam, Baruwa, Elisee, Hofman, Gwen, Machemedze, Solomon, Idiata, Michael Mayombo, Muhemi, Roger, Ndizeye, Olivier, Nkunzimana, Elysé, O’Connor, Jennifer, O’Connor, Zachary, Tchoba, Simplice, Boumas, Natacha, Devidze, Grigol, Pisarevi, Givi, Baumgarten, Sabine, Grüßer, Linda, Hölzle, Frank, Kowark, Pascal, Kowark, Ana, Rossaint, Rolf, Schäfer, Benedikt, Wallqvist, Julia, Winnand, Philipp, Ziemann, Sebastian, Anthuber, Matthias, Broecheler, Tobias, Edlinger, Florian, Goßlau, Yvonne, Hyhlik‐duerr, Alexander, Maksymiw, Florian, Shiban, Ehab, Sommer, Florian, Sommer, Björn, Zerwes, Sebastian, Beyer, Katharina, Lauscher, Johannes Christian, Lee, Lucas D., Loch, Florian N, Schineis, Christian, Aghalarov, Ilgar, Belyaev, Orlin, Braumann, Chris, Enste, Annika, Fahlbusch, Tim, Herzog, Torsten, Horn, Julian, Jedanowski, Julia, Knipschild, Julia, Luu, Andreas Minh, Mohan, Prem Vignesh, Siemen, Leonie, Slobodkin, Illya, Strotmann, Johanna Josefine, Uhl, Waldemar, Wolf, Katerina, Coburn, Mark, Egger, Eva, Eichhorn, Klaus, Enderes, Jana, Far, Frederick, Franzen, Alina, Güresir, Erdem, Hadjiathanasiou, Alexis, Kalff, Jörg C., Kohistani, Zaki, Manekeller, Steffen, Mustea, Alexander, Probst, Chris, Randau, Thomas, Recker, Florian, Schuss, Patrick, Straßberger‐nerschbach, Nadine, Strieth, Sebastian, Treede, Hendrik, Beekum, Cornelius J., Vatter, Hartmut, Velten, Markus, Vilz, Tim O., Wirtz, Dieter, Wittmann, Maria, Behr, Michael, Bulian, Dirk Rolf, Marche, Benedikt, Moczko, Tobias, Otchwemah, Robin, Schulz, Sissy‐amelie, Thomaidis, Panagiotis, Bruns, Christiane, Cursiefen, Claus, Domröse, Christian, Fuchs, Hans, Heindl, Ludwig Maximilian, Mallmann, Michael R., Mallmann, Christoph, Ratiu, Dominik Alexander, Canzler, Ulrich, Distler, Marius, Korn, Sandra, Meisel, Cornelia, Meusel, Marcus, Petzold, Andrea, Praetorius, Christian, Renesse, Janusz, Weitz, Juergen, Wimberger, Pauline, Alkhanji, Nour, Fung, Stephen, Jaber, Kefah, Knoefel, Wolfram Trudo, Vay, Christian, Clonda, Octavian, Cottin, Tatiana, Juodiene, Evelina, Juodis, Domantas, Petrovic, Biljana, Solodarenko, Oleksandra, Binder, Johannes, Grützmann, Robert, Hackner, Danilo, Junker, Stefanie, Arsalan, Mani, Banek, Severine, Chun, Felix, Faqar‐uz‐zaman, Sara Fatima, Keese, Daniel, Kluth, Luis, Rolle, Udo, Van Linden, Arnaud, Walther, Thomas, Bayer, Jörg, Beck, Jürgen, Fung, Christian, Kraus, Luisa Mona, Leiber, Christian, Neidert, Nicolas, Sandkamp, Richard, Schnell, Oliver, Schulte, Antonia, Strähle, Jakob, Jarmusch, Stefanie, Novotny, Helmut Franz Georg, Becker, Johannes, Fulghum, Christian, Gonschor, Bernhard, Herbolzheimer, Marit, Nicolaiciuc, Sina, Trulson, Alexander, Vogelsang, Holger, Zimmermann, Benno, Akbari, Amir Ali, Boening, Andreas, Edinger, Fabian, Hecker, Matthias, Knitschke, Michael, Koch, Christian, Reichert, Martin, Schmidt, Götz, Schneck, Emmanuel, Uhl, Eberhard, Nóbrega, Silvia Flachs, Kauffmann, Philipp, Miller, Clemens, Nemeth, Marcus, Sievers, Denise, Kisser, Ulrich, Kleeff, Jorg, Klose, Johannes, Lorenz, Kerstin, Papendick, Nancy, Plontke, Stefan, Seiwerth, Ingmar, Steer, Susanne, Thomssen, Christoph, Ukkat, Jörg, Dumpies, Christian W., Fischer, Isabel, Gessner, Michael, Hanke, John, Klauke, Friederike, Leuschner, Sebastian, Mendel, Thomas, Müller, Katharina, Schmidt, Birte, Schreiter, Valentin, Stosberg, Peter, Vinz, Franziska, Herbig, Beate, Sander, Johannes, Schulte, Thilo Maria, Betz, Christian Stephan, Bewarder, Julian, Bier, Johannes, Böttcher, Arne, Burg, Simon, Busch, Chia‐jung, Bußmann, Lara, Gosau, Martin, Heuer, Annika, Izbicki, Jakob, Klatte, Till Orla, König, Daniela, Köpke, Leon‐gordian, Moeckelmann, Nikolaus, Praetorius, Mark, Priemel, Matthias, Stadlhofer, Rupert, Stangenberg, Martin, Uzunoglu, Faik G., Wittig, Lukas, Zech, Henrike, Zeller, Nina, Roux, Frederic, Spaeth, Tsiona, Fricker, Roland, Müller, Thomas, Schröder, Lars, Alasmari, Mohammed, Boeker, Clara, Hakami, Ibrahim Abdullah, Mall, Julian W, Kyritsis, Ioannis, Graeb, Christian, Huber‐strößner, Kristin, Branzan, Daniela, Doss, Markus, Gockel, Ines, Jödicke, Carolin, Osterhoff, Georg, Pempe, Christina, Sucher, Robert, Adler, Tina, Kelly, Kathrin, Merkle, Janica, Siebert, Julia, Hirche, Christoph, Kneser, Ulrich, Tapking, Christian, Agrawal, Rachit, Qureischie, Homeira, Croner, Roland, Koslowski, Lisa, Krause, Hardy, Meyer, Frank, Turial, Salmai, Al‐nawas, Bilal, Battista, Marco Johannes, Goedeke, Jan, Hasenburg, Annette, Heider, Julia, Mueller, Lena Katharina, Zeller, Simon, Jentschura, Sina Louisa Patrizia, Kowalewski, Karl‐friedrich, Kriegmair, Maximilian, Männle, David, Reissfelder, Christoph, Rotter, Nicole, Scherl, Claudia, Seyfried, Steffen, Kirschniak, Andreas, Rolinger, Jens, Wilhelm, Peter, Bader, Franz G., Ottl, Stephanie, Behr, Alexandra Viktoria, Diamantis, Alexandros, Fichter, Andreas, Grill, Florian, Heck, Matthias, Jira, Daniel, Kallmayer, Michael, Koll, Florestan, Luhne, Stefan, Meyer, Bernhard, Patachia, Robert, Pergolini, Ilaria, Safi, Seyer, Schäffer, Christoph, Schirren, Moritz, Wegmann, Helmut, Wirth, Markus, Zhu, Zhaojun, Aghamaliyev, Ughur, Almaghrabi, Mahmoud, Böcker, Wolfgang, Bruder, Jan, Frank, Konstantin, Herterich, Viktoria, Huber, Verena, Ilmer, Matthias, Kammerlander, Christian, Neuerburg, Carl, Ehrlich‐treuenstätt, Viktor H., Werner, Jens, Börner, Nikolaus, Fegg, Florian, Hartmann, Daniela, Ladurner, Roland, Liokatis, Paris, Patzer, Kathrin, Schlager, Justin Gabriel, Smolka, Wenko, Zimmermann, Petra, Hatz, Rudolf, Steinhart, Diana, Glowalla, Claudio, Schneidmueller, Dorien, Henkel, Karl Wilhelm, Steiner, Martin, Hölz, Katharina, Knorr, Christian, Kuehlmann, Britta, Oikonomou, Kyriakos, Prantl, Lukas, Flurschütz, Roland, Honarpisheh, Human, Kröger, Marie, Lepiorz, Dominic, Luths, Charlotte, Niemeier, Andreas, Sras, Yara, Strate, Tim, Winter, Thore, Freiman, Thomas, Gessler, Florian, Won, Sae‐yeon, Widyaningsih, Rizky, Hoffmann, Sebastian, Schäfer, Ruth Christine, Thiel, Johannes Tobias, Bertolani, Elisa, Steidle, Christoph, Überrück, Lisa, Yurttas, Can, Ziegler, Patrick, Zimmermann, Alexander, Bolenz, Christian, Dayan, Davut, Greve, Jens, Hoffmann, Thomas K., Janni, Wolfgang, Löbig, Niklas, Schochter, Fabienne, Vahl, Julius Malte, Wezel, Felix, Greif, Veronika, Schmidbauer, Stefan, Marsch, Imke, Schneider, Rolf, Boenicke, Lars, Degener, Stephan, Dreger, Nici Markus, Horstmeier, Franz Christian, Kruschwitz, Jakob, Rombach, Adrian, Schmidt, Nele, Seiberth, Rose, Singh, Jaswinder, Smit, Marieke, Rundstedt, Friedrich‐carl, Zirngibl, Hubert, Diessner, Joachim, Friedrich, Sabine, Germer, Christoph‐thomas, Helmer, Philipp, Herrmann, Johannes, Kranke, Peter, Kübler, Hubert, Lock, Johan, Lotz, Christopher, Meffert, Rainer, Meybohm, Patrick, Müller, Sophie, Notz, Quirin, Popp, Maria, Schlegel, Nicolas, Schlesinger, Tobias, Schmid, Benedikt, Sitter, Magdalena, Steinisch, Andreas, Treutlein, Agnes, Berg, Anne, Wurmb, Thomas Erik, Agyeman‐duah, Nana Kwaku, Appiah, Enoch, Armah, Ralph, Asare, Christopher, Awere‐kyere, Lawrence, Daary, Dennis, Gakpetor, Delali, Allah, Stephen Minlah, Obbeng, Ambe, Osei‐poku, Dorcas, Puozaa, Diana, Tackie, Enoch, Adu‐aryee, Nii Armah, Agboadoh, Nelson, Asare, Offei, Bowan, Antoinette Bediako, Brown, George Darko, Clegg‐lamptey, Joe‐nat, Dedey, Florence, Dery, Cedric, Fenu, Benjamin Sena, Harrison, Marian Abedua, Kumassah, Philemon, Kuuzie, Ekins, Nsaful, Josephine, Olayiwola, David Olatayo, Smith, Cecilia, Banka, Charles, Hussey, Romeo, Azize, Diallo Abdoul, Aniakwo, Luke Adagrah, Adofo‐asamoah, Yvonne, Agbeno, Evans Kofi, Agyapong, Meshach Manu, Agyen, Thomas, Mensah, Kwasi Agyen, Alhassan, Baba Alhaji Bin, Amoako‐boateng, Mabel, Appiah‐thompson, Peter, Gyimah, Nita Asamoa‐Manu, Asante‐bremang, Moses, Asante‐asamani, Alvin, Atawurah, Henry, Appiah, Anthony Baffour, Baidoo, Richard Ogirma, Baidoo, Ebikela Ivie, Boakye, Benedict, Boateng, Abigail, Dadoe, Dora, Dayie, Makafui Seth Caleb‐Joshua Kwasi, Debrah, Samuel, Doku, Kingsley, Enti, Enti, Ken‐amoah, Sebastian, Koggoh, Patience, Kpangkpari, Richard, Maison, Patrick, Mensah, Samuel, Mensah, Philip, Mensah, Teresa Aba, Morna, Martin Tangnaa, Nimako‐mensah, Jilac, Nkrumah, John, Nortey, Michael, Ofori, Emmaunel Owusu, Opandoh, Isabella Naa Morkor, Osei‐tutu, Ethel, Adae, Jefferson Owusu, Quansah, Kofi, Quartson, Elizabeth, Rahman, Ganiyu Adebisi, Walawah, David, Yigah, Makafui, Yussif, Safia, Jiagge, Nuna, Nachelleh, Emmanuel, Acquaye, Jane, Agbedinu, Kwabena, Agyei, Fareeda, Agyemang‐prempeh, Akosua, Amo‐antwi, Kwabena, Amoah, Michael, Amoah, George, Amoako, Yaw A, Aning, Daniel Gyawu, Ankobea‐kokroe, Frank, Mintah, Dominic Annor, Anyitey‐kokor, David, Appiah‐kubi, Adu, Arthur, Joshua, Ativor, Vincent, Barnor, Isaac, Braimah, Yasmine, Darko‐asante, Regina, Davor, Anthony, Issahalq, Mohammed Duah, Dzogbefia, Mawutor, Emile, Tano, Fiifi‐yankson, Papa, Gaveh, Valerie, Gudugbe, Senyo, Gyabaah, Solomon, Gyamfi, Frank Enoch, Gyedu, Adam, Gyimah, Derrick, Hammond, Bernard, Jonathan, Boakye‐yiadom, Joseph, Yorke, Konney, Thomas Okpoti, Konney, Anna, Kusi, Kwasi, Kyei, Ishmael, Lovi, Agbenya, Naabo, Nuhu, Nimako, Boateng, Nyadu, Beauty, Nyarko, Obed Ofori, Ofosu‐barko, Ben Blay, Oppong, Philip Peprah, Osabutey, Anita, Poku, Martha, Sagoe, Robert, Yifieyeh, Abiboye, Ansong, George, Abass, Adam, Abdul‐mumin, Alhassan, Adjeso, Theophilus, Alatiiga, John Abanga, Amadu, Munira, Annan, Nathaniel, Leal, German Azahares, Bukari, Mohammed, Buunaaim, Alexis, Cheyuo, Ernest, Salifu, Latif Daboo, Damah, Michael, Dery, Malcolm, Dzantor, Edem Kojo, Garcia, Odoniel Guerra, Baba, Yabasin Iddrisu, Issaka, Adamu, Muntaka, Abdul‐Jalilu Mohammed, Murphy, James, Agyeman, Yaa Nyarko, Amankwaa, Wisdom Opoku, Osman, Imoro, Pie, Samuel, Seidu, Anwar Sadat, Sheriff, Mohammed, Charadan, Ana Maria Simono, Titigah, Abraham, Yahaya, Mundashiru, Yakubu, Musah, Yenli, Edwin Mwintiereh Ta‐ang, Grypiotis, Ioannis, Kiriakopoulos, Nikolaos, Koliopoulos, Georgios, Kyvelos, Vasilis, Micha, Georgia, Papadopoulou, Triada, Balalis, Dimitrios, Fradelos, Evangelos, Korkolis, Dimitrios, Alexakis, Nicholas, Angelou, Kyveli, Haidopoulos, Dimitrios, Prodromidou, Anastasia, Rodolakis, Alexandros, Thomakos, Nikolaos, Psychogios, Dimitris, Antonakis, Pantelis, Bramis, Konstantinos, Chardalias, Leonidas, Contis, Ioannis, Dafnios, Nikos, Dellaportas, Dionysios, Dimitra, Papalouka, Fragkoulidis, Georgios, Gkiokas, Georgios, Gklavas, Antonios, Hadjizacharias, Theodoros, Karageorgou, Dimitra, Konstadoulakis, Manousos, Kontopoulou, Christina, Massaras, Dimitrios, Memos, Nikolaos, Papaconstantinou, Ioannis, Politis, Dimitrios, Polydorou, Andreas, Stamatis, Konstantinos, Theodosopoulos, Theodosios, Vezakis, Antonios, Avgerinos, Konstantinos, Katunin, Jevgeni, Kechagias, Aristotelis, Kelgiorgi, Dionysia, Kritikos, Neoklis, Pengermä, Pasi, Bisdas, Theodosios, Ioannidis, Argyrios, Konstantinidis, Michael, Konstantinidou, Sofia, Patelis, Nikolaos, Antonopoulou, Maria Ioanna, Deskou, Eirini, Kalles, Vasileios, Manatakis, Dimitrios K., Stamos, Nikolaos, Tasis, Nikolaos, Arkadopoulos, Nikolaos, Danias, Nikolaos, Economopoulou, Panagiota, Frountzas, Maximos, Kokoropoulos, Panagiotis, Michalopoulos, Nikolaos, Selmani, Jonida, Sidiropoulos, Theodoros, Vassiliu, Panteleimon, Paraskevas, Kosmas I., Bartziotas, Dimitrios, Bouchagier, Konstantinos, Galanis, Ilias, Kalamatianos, Theodosis, Kapiris, Stylianos, Kolinioti, Angeliki, Mavrodimitraki, Eleni, Metaxas, Panagiotis, Nikova, Alexandrina, Psarologos, Michail, Sotiropoulou, Maria, Stranjalis, George, Albanopoulos, Konstantinos, Kondilis, Panagiotis, Vrakopoulou, Gavriella Zoi, Chrysovergis, Aristeidis, Chrysovitsiotis, Georgios, Giotakis, Evangelos, Kanellopoulou, Vasiliki, Kyrodimos, Efthymios, Larentzakis, Andreas, Pantos, Pavlos, Papanikolaou, Vasileios, Potamianos, Spyridon, Theodoropoulos, Charalampos, Triantafyllou, Alexandra, Triantafyllou, Tania, Georgousi, Kleoniki, Panagiotou, Peter, Avramidis, Emmanouil, Babis, George, Zafeiris, Evangelos, Antoniou, Afroditi, Bessias, Nikolaos, Maras, Dimitris, Papas, Theofanis, Roditis, Konstantinos, Tsagkos, Ioannis, Tsiantoula, Paraskevi, Alexandrou, Andreas, Baili, Efstratia, Charalabopoulos, Alexandros, Dimitroulis, Dimitrios, Dorovinis, Panagiotis, Garoufalia, Zoe, Kanavidis, Prodromos, Karavokyros, Ioannis, Karydakis, Lysandros, Kykalos, Stylianos, Kyros, Eleandros, Machairas, Nikolaos, Mastoraki, Aikaterini, Nikiteas, Nikolaos, Papalampros, Alexandros, Schizas, Dimitrios, Skotsimara, Antonia, Stamopoulos, Paraskevas, Syllaios, Athanasios, Terras, Alexis, Tomara, Nefeli, Tsourouflis, Gerasimos, Vagios, Ilias, Zografos, Constantinos, Apostolou, Konstantinos, Georgopoulos, Nikolaos, Antoniou, Theofani, Antzaka, Christina, Falara, Areti, Fragoulis, Socrates, Ftikos, Panagiotis, Matsouka, Fedra, Perreas, Konstantinos, Rellia, Panagiota, Samara, Evangelia, Smirli, Anna, Tasouli, Androniki, Thanopoulos, Apostolos, Chalkias, Petros Loukas, Dedemadi, Georgia, Mourmouris, Panagiotis, Skolarikos, Andreas, Theochari, Nikoletta, Tzelves, Lazaros, Gaitanakis, Stylianos, Milas, Theodoros, Theodorakis, Emmanuel, Karona, Paraskevi, Kastanaki, Pagona, Tzouganakis, Angelos, Agalianos, Christos, Tsouknidas, Ioannis, Xenakis, Andreas, Chrysos, Emmanuel, Lasithiotakis, Konstantinos, Nikolouzakis, Taxiarchis, Xenaki, Sofia, Xynos, Evangelos, Lostoridis, Eftychios, Nagorni, Eleni‐aikaterini, Pujante, Antonio, Tourountzi, Paraskevi, Aggeliki, Al, Baxevanidou, Kyriaki, Bouliaris, Konstantinos, Efthimiou, Matheos, Kalfountzos, Christos, Koukoulis, Georgios, Lachanas, Vasileios, Petropoulos, Konstantinos, Tsitiridis, Ioannis, Angelis, Fragkiskos, Arnaoutoglou, Eleni, Baloyiannis, Ioannis, Bareka, Metaxia, Bouronikou, Anna, Christodoulidis, Gregory, Daponte, Alexandros, Fergadi, Maria, Gkolias, Nick, Gkrinia, Eleni, Hajiioannou, Jiannis, Kalogritsas, Nikos, Karoni, Eleni, Korais, Christos, Krestinidis, Giorgos, Ktisti, Antigoni, Magouliotis, Dimitrios, Maiou, Charikleia, Malizos, Konstantinos, Minasidou, Maria, Ntalouka, Maria, Ntziovara, Anna Maria, Palla, Effrosyni, Perivoliotis, Konstantinos, Saini, Fani, Samara, Athina, Saratziotis, Athanasios, Skoulakis, Charalampos, Solomi, Efthymios, Stamoulis, Konstantinos, Terzoudis, Christos Dimitrios, Tsironi, Evangelia, Tzovaras, George, Vallianou, Kyriaki, Zacharoulis, Dimitris, Ziogkou, Anna, Δακής, Κωνσταντί__ς, Elias, Liolis, Maroulis, Ioannis, Mulita, Francesk, Plachouri, Kerasia‐maria, Vailas, Michail, Doitsidis, Charalampos, Filo, Eva, Gkalonaki, Ioanna, Kogia, Eleni, Kontopoulou, Konstantina, Mitroudi, Magdalini, Panteli, Christina, Patoulias, Ioannis, Semkoglou, Olga Ioulia, Sfoungaris, Dimitrios, Valioulis, Ioannis, υτσ_υ μης, Γι ωργος, Astreidis, Ioannis, Christidis, Panagiotis, Ioannidis, Orestis, Loutzidou, Lydia, Mantevas, Antonis, Paraskevopoulos, Konstantinos, Tatsis, Dimitris, Athanasiadis, Apostolos, Dagklis, Themistoklis, Kalogiannidis, Ioannis, Kapetanios, Georgios, Mamopoulos, Apostolos, Margioula‐siarkou, Chrysoula, Petousis, Stamatios, Tsakiridis, Ioannis, Anthoulakis, Christos, Christou, Chrysanthos, Fantakis, Antonios, Iordanidou, Eirini, Kaselas, Christos, Panagiotidou, Sousana, Papadopoulos, Vasileios, Papavasiliou, Kyriakos, Piachas, Athanasios, Siasios, Ioannis, Spyridakis, Ioannis, Theodoridis, Theodoros, Tooulias, Andreas, Tsiridis, Eleftherios, Tsopozidi, Maria, Alemán, María, Brolo, Estuardo, Lemus, Ana Lucia, Greenberg, Jennifer, Chew, Krisna Mishel Morales, Oliva, José Rodrigo, Lima, María Alejandra De León, Muralles, Ismar Lopez, Solares, Felipe, Ajcip, Gaby, Anton, Claudia, Cojulun, Jose, Flores, Mario‐andrés, José, Noriega, Paiz, Carlos Adolfo Marroquín, Morales, Steffanía, Najera, Ramiro, Lorenzana, Eduardo Quiñónez, Rivera, Pablo, Rodas, Lesly, Santos, Victor, Sosa, Dianne, Ybarra, Natalia, Cajti, José David Pérez, Régil, Carlos, Osorio, Walter A, Arriola, Rember Rosales, Talé‐rosales, Luis‐fernando, Herrera, Danilo, Rodríguez, Servio Tulio Torres, Villeda, Sergio Alejandro, Anicetti, Joshua, Medina, Andrea Michelle Lowey, Ardebol, Javier, Barillas, Kathia, De Leon, Francis, Recinos, Salvador, Marroquin‐alpirez, Miguel‐angel, Yax, Yessica, Hon, Sophie, Liu, Yuk Ho, Liu, Alex Qinyang, Liu, Shirley, Chiu, Hei Tung Natalie, Chow, Chi Man Tom, Hau, Victor, Ho Wai, Ip, Mak, Brian, Mok, Chung Ying, Dennis, Ng, Siu, Yin Yu Eva, Wong, Kiu Fung, Jingya Jane, Pu, Yu‐xiong, Su, Au‐yeung, Kit Ying, Chan, David Yuen Chung, Chan, Albert, Chan, Shannon Melissa, Chang, Tsz Ching, Chiu, Tor Wo, Chiu, Wang Kei, Zhexi, He, Man Fung, Ho, Kevin Ki Wai, Ho, Jacky Yan Kit, Ho, Kung, Janet Wui Cheung, Lam, Cheuk Ho, Lau, Rainbow W. H., Ling, Samuel Ka Kin, Lok, Hon Ting, Mak, Tony Wing Chung, Chi‐fai, Ng, Simon, Ng, Kelvin Kwok‐Chai, Ng, Calvin S. H., Ng, Ong, Michael Tim Yun, Tan, Teresa, Tang, Sui Fan, Teoh, Jeremy Yuen‐Chun, Teoh, Anthony, Tsui, Bess Siu Yan, Wong, George Kwok Chu, Wong, Randolph, Wong, Kwok Chuen, Yee, Chi Hang, Antal, Zsuzsanna, Kalman, Attila, Voros, Peter, Bahrehmand, Kiarash, Echim, Timea, Novak, Zoltan, Sztipits, Tamás, Bihari, Laszló ádám, Hidi, László, Piros, Laszlo, Rózsa, Balazs, Sotonyi, Peter, Szatai, Lilla, Herczeg, György, Pordány, Bálint, Tornyi, Fanni, Dede, Kristof, Egyed, Tamás, Saftics, György, Kulcsicka‐gut, Judit, Sipos, Zsófia, Toth, Dezso, Patel, Bhavin, Majmudar, Hardil, Mankad, Saptak, Pathan, Sohilkhan, Sharathkumarkl, L, Sasatti, Lokesh, Mahankali, Subramanyam, Annayappa, Santhosh Kumar Sampengere, Agrawal, Tulika, Anandan, Premkumar, Baindur, Aditya, Manjunath, Bd, Savitha, C, Anitha, G S, Harigond, Sandeep, Tejeswini, K K, Kesarla, Venkatesh, Manangi, Mallikarjuna, Hareesh, P B, Ranjan, Jyothi K R, Shetty, Athish, Chikkanayakanahalli, Santhosh Shivashankar, Sunil, Tanvi, Syamala, Shreya, Tharanath, Kavya, Atal, Aditya, Rajagopal, Niranjana, Srinath, B S, Vinod, Nk, Thirumanikandan, P L, Mishra, Nitu, Shrivastava, Sushruta, Wadhwani, Rekha, Ahmad, Reyaz, Haq, Zainab Ahmad, Behera, Prateek, Dhurwe, Ritika, Haq, Rehan, Jain, Vaibhav, Jain, Anuj, Karna, Sunaina, Pushpalatha, Kameshwarachari, Raj, Sumit, Santoshi, John Ashutosh, Singh, Pooja, Verma, Virendra, Waindeskar, Vaishali, Yadav, Moorat Singh, Aziz, Zaheda, Chakraborty, Koyel, Chappity, Preetam, Das, Gurudip, Datta, Debajyoti, Jena, Saubhagya Kumar, Kar, Madhabananda, Khuntia, Susanta, Kumar, Pankaj, Kumar, Ravi, Aswathi, Kv, Mishra, Abhijeet, Mishra, Swastik, Mittal, Yash, Muduly, Dillip, Panda, Ritesh, Panigrahi, Sibasish, Parija, Sucheta, Patra, Saroj, Rout, Bikram, Sahu, Rabi, Sarkar, Saurav, Singh, Sweta, Sudha, Sanjibani, Sultania, Mahesh, Tripathy, Sujit, Varghese, Paulson, Kansay, Rajeev, Kaushik, Robin, Singh, Simrandeep, Gupta, Sunil Kumar, Khare, Siddhant, Kumar, Vishal, Mohindra, Sandeep, Patil, Ninad, Salunke, Pravin, Savlania, Ajay, Singh, Kavindra, Pradeep Krishna, Rv, Narasimhan, Gomathy, Rela, Mohamed, Appukuttan, Akhila, Goudar, Swati, Mallick, Shweta, Titus, Christi, Chidambarasamy, Ezhir Selvan, Madhavan, Devdas, Murugesan, Anandan, Narayanasamy, Kuppurajan, Barani Kumar, P B, Rajan, Firoz, Vijayaragavan, Paari, Kumar, Arvind, Borthakur, Biplob, Chauhan, Tapan Singh, Govil, Akhil, Gupta, Shubhra, Hanjoora, Vijay Mohan, Sharma, Ashish, Srivastava, Aseem, Tiwari, Saurabh, Vishwani, Vartika, Pendyala, Karuna Sree, Prasad, Navakoti, Bothra, Jyoti, Deb, Mainak, Herle, Koushik, Jayaram, Harish, Kannaiyan, Lavanya, Krithiga, Abirami, Mukta, W, Nagpal, Pooja, Pathak, Prachi, Banerjee, Sumit, Chaudhary, Ramkaran, Choudhary, Gautam Ram, Chugh, Ankita, Dixit, Pawan, Elhence, Abhay, Gahlot, Nitesh, Garg, Mayank, Ghuman, Navdeep Kaur, Jha, Deepak, Kala, Prakash, Kaur, Amanjot, Madduri, Vijay, Pandey, Himanshu, Pareek, Puneet, Pathak, Manish, Rathod, Kirtikumar J, Rodha, Mahaveer Singh, Saxena, Rahul, Sharma, Naveen, Shekhar, Shashank, Singh, Mahendra, Singh, Pratibha, Suryanarayanan, Bhaskar, Vishnoi, Jeewan Ram, Amin, Shivang, Kumar, Rohit, Sharma, Tanishq, Murugesan, Kesavan, Ramasamy, Abhinav Balachandar Subbiah, Chatterjee, Debarshi, Gerber, C Gerber, Naskar, Upasana, Aggarwal, Gaurav, Agrawal, Sanjit Kumar, Ahmed, Azaz, Gupta, Sujoy, Jain, Prateek, Jain, Deepak, Kewlani, Vishal, Pipara, Amrit, Priya, Noopur, Raja, Roopak, Shakya, Sudip, Thambudorai, Robin, Kharkongor, Dimple, Agarwal, Anjoo, Akhtar, Naseem, Anand, Akshay, Asnani, Mona, Chaturvedi, Arun, Chaurasia, Akhilanand, Enny, Loreno E., Garg, Surabhi, Gupta, Sameer, Jaiswal, Anoop Kumar, Jaiswal, Somil, Jaware, Yashpal, Kala, Navneet, Karnatak, Ruchi, Kaur, Apjit, Kumar, Vijay, Kumar, Manoj, Kumar, Ambrish, Kumar, Upander, Shrivastava, Amit Kumar, Mehrotra, Seema, Mishra, Brijesh, Mishra, Anand, Namrata, Null, Ojha, Bal Krishna, Ozair, Ahmad, Pal, Uma Shanker, Pandey, Amita, Raja, Nancy, Ramakant, Pooja, Roy, Ashutosh, Sachan, Rekha, Sankhwar, Satyanarayan, Sankhwar, Pushp, Sarin, Divya, Shukla, Ayushi, Singh, Sushil, Singh, Mohit, Singh, Kul Ranjan, Singh, Renu, Singh, Uma, Singh, Urmila, Solanki, Vandana, Sonkar, Abhinav Arun, Srivastava, Chhitij, Suryawanshi, Parijat, Tewarson, Vivek, Verma, Rajat, Verma, Manju Lata, Yadav, Awdhesh, Chand, Gyan, Chanthar, K. M. M. 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Giorgio, Fappiano, Francesca, Pacilio, Carlo Alberto, Solaini, Leonardo, D’Andrea, Giancarlo, Lavalle, Laura, Picotti, Veronica, Barberis, Andrea, Filauro, Marco, Santoliquido, Matteo, Aprile, Alessandra, Barra, Fabio, De Rosa, Raffaele, Diaz, Raquel, Ferrero, Simone, Fregatti, Piero, Gustavino, Claudio, Iester, Michele, Kratochwila, Chiara, Massobrio, Andrea, Pertile, Davide, Scabini, Stefano, Scovazzi, Umberto, Soriero, Domenico, Sparavigna, Marco, Traverso, Carlo, Vagge, Aldo, Gambardella, Denise, Tedesco, Manfredo, D’Ugo, Stefano, Depalma, Norma, Spampinato, Marcello Giuseppe, Airoldi, Angelo, Brivio, Ariberto, Chiarelli, Marco, Gibelli, Ludovica, Giulia, Bonfanti, Grandi, Samuele, Pesenti, Giovanni, Tagliabue, Fulvio, Zago, Mauro, Lenzi, Riccardo, Matteucci, Jacopo, Muscatello, Luca, Colletti, Gaia, Confalonieri, Marco Guido, Costanzi, Andrea, Frattaruolo, Colomba, Locatelli, Andrea, Monteleone, Michela, Badessi, Giorgio, Caffo, Maria, Caruso, Gerardo, Cucinotta, Eugenio, Germano, Antonino Francesco, Mazzeo, Carmelo, Bertoglio, Camillo Leonardo, De Martini, Paolo, Ferrari, Giovanni, Giani, Alessandro, Lombardi, Pietro Maria, Mazzola, Michele, Baldari, Ludovica, Bissacco, Daniele, Boni, Luigi, Cassinotti, Elisa, Domanin, Maurizio, Pignataro, Lorenzo, Torretta, Sara, Trimarchi, Santi, Armellin, Daniele, Basato, Silvia, Bernardi, Laura, Bunino, Francesca, Capretti, Giovanni, Carrano, Francesco Maria, Castoro, Carlo, Colombo, Giovanni, Costantino, Andrea, De Lucia, Francesca, De Virgilio, Armando, Di Bari, Matteo, Ferreli, Fabio, Gaino, Francesca, Gramellini, Marco, La Raja, Carlotta, Malvezzi, Luca, Marano, Salvatore, Mercante, Giuseppe, Milana, Flavio, Nappo, Gennaro, Peros, Georgios, Pirola, Francesca, Rossi, Vanessa, Russo, Elena, Spriano, Giuseppe, Tamburello, Sara, Zerbi, Alessandro, Aiolfi, Alberto, Bona, Davide, Sozzi, Andrea, Adamoli, Laura, Ansarin, Mohssen, Bertolaccini, Luca, Cenciarelli, Sabine, Chu, Francesco, De Berardinis, Rita, Romario, Uberto 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Andreani, Lorenzo, Antonio, Darienzo, Aprile, Vittorio, Balestri, Riccardo, Benettini, Giacomo, Berrettini, Stefano, Bruschini, Luca, Chiarugi, Massimo, Coccolini, Federico, Colangeli, Simone, Cremonini, Camilla, Mencacci, Lodovica Cristofani, Dallan, Iacopo, De Santi, Silvia, Di Franco, Gregorio, Di Girolami, Lorena, Fiacchini, Giacomo, Furbetta, Niccolò, Korasidis, Stylianos, Lucchi, Marco, Morandi, Andrea, Morelli, Luca, Musetti, Serena, Neri, Carlo Maria, Palmeri, Matteo, Picariello, Miriana, Porcelli, Francesco, Puccini, Marco, Roffi, Nicolo, Statuti, Erica, Tartaglia, Dario, Tonelli, Alberto, Vianini, Matteo, Baronio, Gianluca, Montuori, Mauro, Pinotti, Enrico, Basso, Stefano Maria Massimiliano, Maffeis, Federica, Ubiali, Paolo, Aguzzoli, Lorenzo, Coiro, Saverio, Falco, Giuseppe, Mandato, Vincenzo Dario, Mastrofilippo, Valentina, Mele, Simone, Baldi, Caterina, Corbellini, Carlo, Sampietro, Gianluca Matteo, Dugo, Massimo, Garino, Mauro, Marafante, Chiara, Masciandaro, Antonio, 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Francesco, Altana, Cristian, Bussu, Francesco, Capobianco, Giampiero, Carta, Anna Giacomina, Ciccarello, Sandro, Cossu, Maria Laura, Cottu, Pietrina, De Riu, Giacomo, Dessole, Salvatore, Dessole, Francesco, Dettori, Salvatora, Doria, Carlo, Fancellu, Alessandro, Feo, Claudio F, Ginesu, Giorgio Carlo, Giuliani, Giuliana, Iannuccelli, Marco Giuseppe, Madonia, Massimo, Mancino, Roberto, Massarelli, Olindo, Meloni, Gianfranco, Milia, Fabio, Mulliri, Andrea, Perra, Teresa, Petrillo, Marco, Piras, Antonio, Piredda, Franco, Pisanu, Francesco, Porcu, Alberto, Rizzo, Davide, Sanna, Angelino, Scanu, Antonio Mario, Scognamillo, Fabrizio, Soma, Damiano, Tanca, Anna Rita, Tedde, Alessandro, Tedde, Matteo, Vaira, Luigi Angelo, Pazzi, Andrea Bartalini Cinughi, Samorani, Osvaldo Carpineto, Fusario, Daniele, Marano, Luigi, Oldrà, Gaia, Pesce, Anna Lisa, Piccioni, Stefania Angela, Resca, Luca, Ricchiuti, Vincenzo, Roviello, Franco, Savelli, Vinno, Abrate, Alberto, Bordoni, Pierpaolo, Bosio, Lorenzo, 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Rinaldi, Mauro, Ruffini, Enrico, Salizzoni, Stefano, Bardelli, Laura, Berselli, Mattia, Borroni, Giacomo, Cocozza, Eugenio, Desio, Matteo, Elisa, Bottazzoli, Ietto, Giuseppe, Iori, Valentina, Iovino, Domenico, Livraghi, Lorenzo, Marchionini, Valentina, Megna, Stefano, Nahal, Emma Amal, Palumbo, Mara, Quintodei, Valeria, Zullo, Alessandra, D’Alimonte, Lucrezia, Pirozzolo, Giovanni, Vignotto, Chiara, Campagnaro, Tommaso, Caravati, Andrea, Conci, Simone, De Cristofaro, Carlotta, Gecchele, Gabriele, Giuliani, Tommaso, Graziosi, Jacopo, Guglielmi, Alfredo, Paiella, Salvatore, Pedrazzani, Corrado, Pollini, Tommaso, Rattizzato, Simone, Ruzzenente, Andrea, Salvia, Roberto, Turri, Giulia, Bacchion, Matilde, Butturini, Giovanni, Casaril, Andrea, Giardino, Alessandro, Impellizzeri, Harmony, Inama, Marco, Isabella, Frigerio, Moretto, Gianluigi, De Zuanni, Marco, Deiana, Enrica, Guglielmo, Mario, Broglia, Alessandro, Casarini, Claudia, Zingaretti, Caterina Costanza, Bonaldi, Marta, Cesana, Giovanni, Mastriale, Francesco, Olmi, Stefano, Fukami, Matteo Uccelli Yasuyuki, Saito, Takuya, Sano, Tsuyoshi, Hirai, Naoki, Hirota, Kazuyoshi, Kushikata, Tetsuya, Oyama, Tasuku, Saito, Junichi, Ishibashi, Katsuhiko, Kamiyama, Mizue, Son, Kyongsuk, Tarao, Kentaroh, Yamada, Takayuki, Shiga, Toshiya, Aze, Chisaki, Deguchi, Yoshihiko, Hasegawa, Hirotoshi, Hoshino, Tatsuki, Innami, Yasushi, Inoue, Hiroyuki, Ito, Shingo, Nomura, Takeshi, Ogihara, Tomomi, Okada, Reina, Ouchi, Takashi, Sekiya, Yuri, Tachibana, Keikoku, Takano, Emi, Yamamoto, Masae, Matsuda, Shuko, Matsuki, Yuka, Shigemi, Kenji, Hiraki, Teruyuki, Inoue, Yui, Jotaki, Shosaburo, Abe, Tatsuro, Eto, Masatoshi, Inokuchi, Junichi, Kashiwagi, Eiji, Kinoshita, Fumio, Kobayashi, Satoshi, Lee, Ken, Matsumoto, Takashi, Monji, Keisuke, Naganuma, Hidekazu, Shiota, Masaki, Takeuchi, Ario, Obara, Shinju, Takatsuki, Saori, Tanaka, Saori, Iida, Koji, Kagawa, Kota, Neshige, Shuichiro, Chaki, Tomohiro, Hirata, Naoyuki, Kazuma, Satoshi, Kimizuka, 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Mieko, Hirano, Kouichi, Kobayashi, Yoichi, Matsuki, Ryota, Matsumoto, Hironori, Motoyasu, Akira, Nakazawa, Harumasa, Noguchi, Hikari, Okamura, Kaio, Ono, Motoaki, Seki, Hiroyuki, Sunami, Eiji, Tajima, Atsushi, Tanigaki, Shinji, Uzawa, Kohji, Watanabe, Hidenobu, Furuhata, Yukari, Toyama, Satoshi, Uchida, Tokujiro, Enomoto, Yutaka, Furukawa, Yuri, Hasumi, Yoko, Hirota, Jinso, Iida, Katsuyuki, Ikeda, Shingo, Ikeda, Tatsuhiko, Kawamata, Natsuko, Kawasaki, Yosuke, Koizumi, Minako, Kono, Yoshiharu, Kuzuhara, Shigeki, Maeda, Junichi, Moriyama, Mai, Nagamoto, Shoichi, Nakanishi, Rinako, Noda, Michio, Seichi, Atsushi, Takahashi, Shintaro, Takashi, Kobayashi, Takeda, Misuzu, Tanakura, Kenta, Terajima, Katsuyuki, Tsuji, Munechika, Ueshima, Chiharu, Yamamoto, Naoya, Yamamoto, Mari, Yokota, Toshiya, Yoshioka, Yuki, Yuri, Sakoh, Iwata, Shintaro, Kawai, Akira, Osaki, Shuhei, Ishikawa, Masashi, Iwasaki, Masae, Morita, Tomonori, Hirooka, Reina, Nakata, Yoshinori, Sawamura, Shigehito, Ishida, Yusuke, Kawachi, Aya, Kobayashi, Takayuki, Nagashima, Fumiaki, Suzuki, Naoki, Ando, Kohei, Miyazawa, Noriko, Tanaka, Yukio, Abuissa, Khatab, Aljabali, Alaa, Almasri, Amal, Alrabadi, Mera, Alshara, Rana, Alzghoul, Yasmeen, Alzughoul, Ahmed, Freihat, Ali, Jeitan, Emran, Owais, Qais, Smadi, Aseel, Abukhadra, Mahmoud, Abunawas, Huthifa, Al‐azzam, Abdallah Ahmed Mezel, Aladaileh, Ammar, Albadawi, Ismail, Alhawatmeh, Mohammad, Alkhaza’Leh, Mohannad Yaser, Alneimat, Roaa Salem Jwaid, Alwahedy, Saba, Alwardat, Abdel Rahman Mohannad Ahmad, Dhoon, Slsabela, El‐qawaqzeh, Khaled, Hrerat, Tarteel, Jaradat, Enas, Mubaydeen, Teeba, Sarayrah, Husam, Tarawneh, Mohammad Abdel Elah A., Karasneh, Mohammad Yousef, Zurgan, Amany, Alassaf, Mohammad, Alzraikat, Sayel H., Amarin, Justin Z., Hijjawi, Ahmed, Suradi, Haya H., Zaghlol, Louay Y., Abdalah, Ahmad, Abdallah, Ghaida, Tarieh, Ammar Abu, Abu‐libdeh, Tareq, Abualteen, Faisal, Al Abdallah, Murad, Al Bdour, Zakaria, Al Dahabrh, Seif, Al‐kasaji, Farah, Ali, Zaid Al‐sheikh, Al‐thaher, Mohammad, Alnajjar, Tareq, Alqedrh, Mohannad, Alsaleh, Mohammad, Alzaatreh, Mohammad, Amayreh, Ghandi, Ayasra, Yazeed, Eid, Ahmad, Ghayada, Ibrahim, Moh’d Ahmed Hasanein, Khaled, Hassouneh, Anas, Hijazeen, Raid, Hmeidan, Majedah, Khaled, Ahmed, Khasawneh, Barihan, Kifayeh, Omar, Lafi, Yasser, Seba, Jasem, Semrin, Qusai, Sma, Fda, Theab, Mohammad, Tumeh, Haitham, Zaid, Muna Aba, Abazeed, Alaa, Abbad, Bader, Abbadi, Osaid, Abu‐ishkerih, Nizar, Al‐osta, Malk, Al‐zyadat, Reham, Alawneh, Bashar Omar Falah, Alhattab, Majd, Alkurdieh, Mohd Mujahed, Awwad, Ziad, Hammouri, Mohammad, Hussein, Hamzeh, Khader, Sereen, Khalil, Mariam, Mansour, Omar, Othman, Ahmad, Qandeel, Haitham, Saleem, Mohammad, Souri, Fouad, Tahboub, Ahmad, Tayyem, Raed, Abdallah, Munir, Abdel‐hafez, Ibrahim, Obead, Hamza Abu, Abudari, Hadeel, Abuhamour, Ehab, Abusadah, Samer, Al‐azzeh, Nimer, Al‐adwan, Sofian, Al‐darabah, Ali, Al‐qannas, Mohammad, Albaba, Basil, Alradawneh, Qutaiba, Amaireh, Mohammad, Ashour, Subhi, Chabaan, Reem, Eskander, Ammar, Fawzi, Ahmad, Haij, Manal, Hamad, Hisham, Hamdan, Haya, Hamss, Ahmed, Hassouneh, Esraa, Hyasat, Ayah, Ibrahim, Zainab, Jamaliah, Saja, Khalil, Mohammed, Massad, Anas, Mohamed, Ishak, Qandeel, Mahmoud, Qasrawi, Dalia, Raggad, Mahmoud, Rifai, Ebaa, Semreen, Nedal, Shehada, Reham, Shorman, Marwan, Al‐shibi, Abdallah, Alsa’Afin, Shatha, Bani‐hani, Morad, Nimer, Bahaa, Nofal, Sandra, Qaraqe, Layth, Salameh, Mohammed, Saleh, Ma’Moun, Sanjuq, Ghaidaa, Sharabi, Alaa, Sweiti, Alaa, Yaghmour, Jamal, Zaza, Sabri, Alhindi, Rahaf, Baninasr, Eman, Al‐masri, Mahmoud, Al‐najjar, Hani, Alawneh, Fade, Al‐latayfeh, Motasem, Al‐shudifat, Abdel‐ellah, Ahmad, Abd Almonem Shaikh, Abdeljalil, Abdelkarim, Abdelrahman, Haneen, Abdulmalek, Abdulmalek, Abedalqader, Lina, Abed, Laith Abu, Al Smadi, Omar, Alarood, Salameh, Allouzi, Mohammad, Almansour, Maha, Almi’Ani, Sari, Alsaiad, Abdulhakim, Alshaikh, Khaled, Androus, Farah, Awbakh, Mirna, Azzam, Belal, Yasin, Hammam Bany, Daoud, Maher, Dawod, Lujain, Dawod, Omar, Elmusa, Reem, Fadli, Saba, Hammad, Farah, Hunaiti, Majd, Muhtaseb, Mahmoud, Owaimer, Rawan, Qulaghassi, Zaki, Romman, Saleh, Saket, Rawand, Sharawi, Said, Tawalbeh, Alaa, Al‐howthi, Mohammed, Ababneh, Laila, Ababneh, Roba, Za’Nouneh, Faris Jamal Abu, Al DHOUN, Sajedah, Al Khassawneh, Ahmad, Al Sharie, Ahmed, Al Shraideh, Ayah Ahmad, Al‐dabaa, Tawfik, Al‐jarrah, Salsabeel, Al‐jarrah, Hothaifa, Al‐othman, Hadeel, Alaradi, Zuhair, Alshannaq, Qutaiba, Alsulaiman, Rima, Alzaqh, Motasem, Alzu’Bi, Yazan, Audat, Ziad, Bahhour, Mohammad, Bdour, Saja, Khatatbeh, Roa, Marji, Fares, Mazahreh, Tagleb, Nail, Dina, Nuseir, Amjad, Rabab’Ah, Asmaa, Sawadi, Taher, Zidan, Ghina, Muhfouz, Dima Abu, Nael, Abdullah, Qasim, Ahmad, Al‐jarrah, Amar, Rawagah, Faisal, Abu Ismail, Dima Y, Al‐dolat, Wedad, Alzoubi, Mai, Alzoubi, Malak, Alzu’Bi, Mu’Taz, Asha, Ruba, Guboug, Ali, Hussein, Hasan, Rawashdeh, Shireen, Sanwar, Mohammad, Ababneh, Adnan, Abu‐eisheh, Basil, Alhami, Haneen Ahmad, Al Dwairi, Saif Aldeen, Al Shurman, Hana’, Al Yahya, Zakaria, Al‐atiyah, Hussam, Al‐balas, Hasan, Aljaiuossi, Anas, Alqawasmi, Shatha, Alqudah, Sadeel, Alshourman, Mahmoud, Hamad, Abdulsalam Bani, Issa, Anas Bany, Ennab, Raed, Hamdoni, Sara, Hijazi, Zaid, Khafaja, Ali, Mraiyan, Mohamed, Obeidat, Riyad, Olaywah, Dina, Qudah, Mohamad, Talal, Mhamdd, Aidarov, Askar, Sarmenova, Aisulu, Kodasbaev, Almat, Sakhov, Orazbek, Tanabayeva, Shynar, Amrayev, Sultan, Dzhumabekov, Berik, Malgazhdarov, Maulen, Tezekbaev, Kanat, Kukubassov, Yerlan, Satanova, Alima, Mwachiro, Michael, Parker, Robert, Simel, Ian, Mohammedali, Shamshuddin, Mwaria, Claude, Obure, Ralph, Shah, Sayed Shah Nur Hussein, Hirani, Chetan, Kibunyi, Muthoni, Mailu, Claire, Mwangi, Victor, Ogenya, Roy, Osea, Lydia, Cheruiyot, Davies, Hirsi, Omar, Muiru, Carolyne, Wanjara, Samuel, Kim, Chang Woo, Lee, Suk Hwan, Almulla, Ahmad, Dashti, Mustafa, Elghany, Omar, Sultan, Abdullah, Al‐mahmeed, Husain, Alabbad, Jasim, Albader, Ibtisam, Aldalal, Shuaib, Baba, Mahdi, Abdulsalam, Fareed, Alhajri, Naser, Alwael, Athari, Ayele, Brook, Marie, Hatem, Zaitoun, Ahmed, Alali, Ahmad M., Alkhamis, Ahmed, Alozairi, Ous, Almazeedi, Sulaiman, Alsabah, Salman, Abdelkarim, Mostafa, Al Rashed, Asmaa, Al Subaie, Saud, Al‐shaiji, Tariq, Al‐terki, Abdullatif, Alhunaidi, Omar, Aljewaied, Ali, Alzamel, Khaled, Farag, Ahmed, Hayati, Hussein, Termos, Salah, Wood, Sarah, Al‐gilani, Maha, Al‐sihan, Mutlaq, Alotaibi, Haifa, Lobovs, Dmitrijs, Pcolkins, Andrejs, Sivins, Armands, Apse, Ingus Arnolds, Berga, Annija Evelīna, Ivanova, Anna, Demicevs, Jevgenijs, Ivanovs, Igors, Kaminskis, Aleksejs, Opincans, Janis, Pāvulāns, Jānis, Rudzāts, Agris, Udre, Anna, Dbouk, Samer, Farfour, Imadeddine, Rakka, Mohamad, Antonios, Ingrid, El Hage, Joe, Hage, Stephanie, Haiby, Lea, Kahi, Hiba, Lichaa, Anthony, Moussa, Rita Milan, Salameh, Michel, Sarkis, Riad, Albaini, Obey, Haykal, Tony, Safadi, Bassem, Abou‐abbass, Hussein, Al Makari, Reem, Al Zein, Zeina, Baidoun, Mariam, Itani, Rania, Owiedat, Mustafa, Abdel Sater, Ali H., Akl, Michel, Badran, Nour, El Mustapha, Sara, Fatouh, Fathallah, Ghoussoub, Youssef, Saad, Nader, Serhan, Fatima, Souleiman, Bassem, Alame, Walid, Ghiya, Peter, Ibrahim, Firas, Abdallah, Rasha, Kassab, Mohamad B., Karout, Samar, Aya Abdul, Al, Chaaban, Hilal, Fakih, Ghinwa, Haj‐ibrahim, Huzifa, Awad, Rabih, El Assaad, Hadi, Alfeqeeh, Ahmed, Muftah, Hosam, Abdulrahman, Taha, Ahseen, Naeimah, Abunaaja, Hayat Omar, Abdulmalik, Abdulmuez, Al Gasi, Abd El Jawad, Alsaeiti, Sara, Elkhafeefi, Fatimah, Elrefai, Nasre, Ahmad, Rofida, Alhouni, Tarek, Alkarky, Safya, Alkeelani, Hana, Alkuwafi, Rauoof, Benhariz, Rema, Bettamer, Nagat, Busarira, Musa, Bushaala, Hassan, Diryaq, Tariq, Elbargathe, Osama, Eldarat, Tarik, Elfadli, Mustafa, Elfitori, Jamael, Elmahgoub, Asma, Elsahti, Reem, Hassan, Yosef, Hussain, Fathi, Mirsal, Taha, Mohammed, Marwa, Saad, Ebtesam, Hadad, Haifaa Il, Mosabha, Mostafa, Alhaje, Awatif, Haron, Aaya, Alsuwiyah, Suhir, Hamed, Mona, Khel, Samer, Omar, Sana, Yousef, Rowaida, Abdelmalik, Abubaker, Abosnaina, Yahya, Abuhlaiga, Ma’Aly, Abushahma, Ahmed Omar, Aldelensi Alzubi, Alhosen Saleh M, Aljanfi, Asma, Alnehum, Mohamed Alnaser, Alzedam, Ahmad, Delhen, Malik, Maderi, Galia, Matoug, Faisel, Mohammed, Burooj, Sawalem, Mohamed, Jahan, Alhadi, Jahan, Abdussalam, Alazabi, Basma, Alezabi, Bahauldin, Alazabi, Mona Masaud Amro, Egdeer, Amin Salem Ahmed, Sefi, Fatma, Kamoka, Elhusain, Salamah, Abdulrauf, Abdalhadi, Alya, Abdeewi, Saedah, Alhadad, Marwah, Awrayit, Ahmed, Eshnaf, Mabroka, Yahmad, Mohammad, Abudher, Abdulhafid, Elamin, Faisl, Abojeila, Farah, Aliwa, Mohamed, Jouira, Rayet Al Islam Ben, Shagour, Sana, Altobal, Ahmed, Aljuroushi, Omar, Almadani, Hadeel, Attia, Hajer, Eljali, Amal Sharif, Emran, Ayyah, Omar, Mabruka, Salim, Radhwan, Samer, Ashraf, Abulshuwashi, Nayrouz Abdullah, Ben Khalifa, Emadeddin T M, Benabdalla, Hdaya Abdalla S, Elnageh, Hatem, Hammad, Ali, Abdullah, Duha Milad, Abusalem, Marwa, Esmael, Esraa Ben, Benmasoud, Fatma, Debri, Laila, Elmokhtar, Randa, Sheta, Manal Ezeddin Kamel, Elhabashi, Bushra Sayeh Mohamed, Younis, Balkees, Elmabrouk, Amna, Momen, Ahmed, Alzoubi, Abdalrahem Essied Alzubi, Ayad, Kusay, Hasan, Ameerah Mahdi Abraheem, Musrati, Fawzie, Abusannoga, Malek, Malek, Ans, Ajaj, Hatem, Abdulwahed, Eman, Aboubeirah, Mohammed, Alqurpaa, Aya, Alshareea, Entisar, Aribi, Sarra, Aribi, Tomather, Biala, Marwa, Ghamgh, Reem, Issa, Mohannned, Lamari, Amani Hamid, Mufth, Mohammed, Abboud, Omar Sudig, Hallalah, Muad Fathi Khalleefah Abu, Abumahara, Saleh, Aburima, Sarah, Adrees, Mohammed, Ahtash, Abdurahman, Al Shukri, Asmaa, Alameen, Hind, Alarabi, Rehab, Alarabi, Alarabi, Alelwany, Aisha, Alesmail, Abdulkarim, Algadi, Noran, Almaqrahi, Khuloud, Alosta, Hadel, Alsharedi, Mohamed, Bashir, Rasha, Ghrema, Mahmoud Ben, Nour, Sari Bin, Elbarouni, Sofian, Elhadi, Ahmed, Elkhadar, Abdulmohimen A, Elkouba, Esraa, Elmsherghi, Nabiha, Gammoudi, Abdulmohimen, Ghariba, Abdulraouf, Gjam, Fatima Zayed, Haidar, Arwa, Helal, Hala, Huwaysh, Mohammed, Alhadheeri, Ahmed Khalid, Kriem, Eslam, Osman, Halim, Ossman, Mohamed Ali, Shilfeet, Marwah, Turshani, Laila, Albishty, Nouran, Alhadi, Abdulmueti, Ali, Salem, Altoumi, Manal Ahmed, Bahroun, Sumayyah Ghayth, Younes, Eman, Atarabulsi, Hana, Elshaibi, Mohamed, Othman, Abdullmujeeb, Hasan, Hayat Ben, Hasan, Najat Shaban Ben, Hasan, Rabab Shaban Ben, Barauskas, Vidmantas, Dainius, Edvinas, Dambrauskas, Zilvinas, Dauksa, Albertas, Dekeryte, Inga, Gudaityte, Rita, Jasaitis, Kristijonas, Koženiauskaitė, Akvilė, Krasauskas, Virgilijus, Lukosiute‐urboniene, Ausra, Maleckas, Almantas, Riauka, Romualdas, Šlenfuktas, Vygintas, Svagzdys, Saulius, Urbonas, Kestutis, Vanagas, Tomas, Venclauskas, Linas, Venskutonis, Donatas, Zilinskas, Justas, Ambrazevicius, Marijus, Syminas, Vilius, Aliosin, Oleg, Cizauskaite, Agne, Eismontas, Vitalijus, Jurgaitis, Jonas, Mikutaitis, Vytenis, 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Mamisoa, Solo, Corinne Eulalie, Ralaizafindraibe, Tojomamy Herinjaka, Andofenohasina, Fanonjomahasoa Safiry, Rasataharifetra, Hanta, Razafindraibe, Vanona Barijaona, Herinirina, Angelin Sablon, Das, Andre, Ganapathy, Thanga, Gunarasa, Yohesuwary, Mariapan, Kalyani, Muniandy, Maathichsudhaar, Osman, Mohd Firdauss, Azmi, Mohd Azem Fathi Mohammad, Soh, Jien Yen, Zain, Wan Zainira Wan, Zakaria, Andee Dzulkarnaen, Zakaria, Zaidi, Chan, Kheng Hooi, Hayati, Firdaus, Johan, Syamim, Mah, Jin Jiun, Sriram, Ratha Krishnan, Subramaniam, Sentilnathan, Shahimi, Nur Shahirah Binti Muhammad, Hamdan, Khairul Hazim, Ibrahim, Mohd Razali, Muthkumaran, Guhan, Tan, Ju Ann, Thanapal, Mohana Raj, Aziz, Dayang Anita Abdul, Bastion, Mae‐lynn, Harun, Mohd Hairul Nizam, Imran, Farrah‐hani, Din, Norshamsiah Md, Zain, Ayesha Mohd, Mustapha, Mushawiahti, Nabil, Syed, Naffi, Ainal Adlin, Nazimi, Abd Jabar, Ramli, Roszalina, Soon, Bee Hong, Bal, Pavin, Cheng, Joo Qing, Draman, Mohd Rusdi, Fadzli, Ahmad Nazran, Ghauth, Sakina, Hung, Weipin, Jamaris, Suniza, Koh, Peng Soon, Krishnasamy, Sivakumar, Lee, Yeong Sing, Liew, Yew Toong, Lim, Jeffery Zk, Lim, Raymond Chung Siang, Lim, Hiong Chin, Pauzi, Siti Farhan Moh, Nah, Shireen Anne, Nair, Ashvin Krishna, Doris Sin Wen, Ng, Yong, Yuki Julius Ng We, Ramayah, Kamarajan, Saaid, Rahmah, Sanmugam, Anand, See, Mee Hoong, Seevalingam, Kanesh Kumaran, Sethi, Neha, Singaravel, Srihari, Zaidi, Syeda Nureena Syed Jafer Hussain, Tang, Chu Yik, Teoh, Li Ying, Wong, Kian Boon, Xavier, Ruben, Yahaya, Ahmad Shuib, Norhafiza, Ab, Rahman, Null, Islah Munjih, Ab, Rashid, Null, Aziz, Mohd Fahmi Abd, Rahman, Mohd Norhisham Azmi Abdul, Amjad, Nasser Muhammad, Alhadi, Shahidah Che, Elagili, Faisal, Kamarulzaman, Mohd Nazli, Nor, Azmi Md, Othman, Ahmad Faidzal, Sainal, Mohd Yusof, Sarif, Mat Salleh, Chua, Richelle, Ibrahim, Aini Fahriza, Ahmad, Abdul Rauf Bin, Lau, Yii Ling, Liew, Ka Yee, Palayan, Kandasami, Wong, Hui Yu, Zakaria, Jasiah, Aziz, Nor Azimah Abd, Rahim, Norazila Abdul, Rahman, Noorneza Abdul, Abdullah, Bahiyah, Sikkandar, Mohamed Faizal Bin, Firman, Fatin, Hazleigh, Nik Mohd, Kamarudin, Intan Kartika, Khalid, Shahril, Miswan, Mohd Fairudz Mohd, Zahid, Akmal Zulayla Mohd, Mustafa, Norasyikin, Obaid, Kadhim, Yahaya, Mohd Yusoff Bin Yahaya, Yusoff, Ahmad Ramzi, Andrejevic, Predrag, Myatt, Jeremy Borg, Brincat, Svetlana, Caruana, Clifford, Chircop, Kurt Lee, Chircop, Francesca, Chircop, Daniel Mario, Cini, Charles, Czok, Viktoria, Farrugia, Melanie, Grima, Gabriella, Almukhariq, Fatimah MJ Hassan, Muscat, Esther, Pisani, Darryl, Roshan, Mohsin Hassan Khan, Schembri, Nicholas, Shoukry, Mohamed, Spiteri, Neville, Tanti, Gilbert, Hasan, Ziad Aboharp, Soto, Alberto Bazan, Rubén, Cedillo Rodrìguez Jonathan, Zamudio, Gustavo Esteban Lugo, Gómez, David Gerardo Miranda, Meave, José Alfredo Pérez, Victor Pinto Angulo, Null, Aguilar, Antonio Rojas, Duran, Erik Efrain Sosa, Perez, Alejandro Vàzquez, Arroyo, Diego, Corona‐cruz, Jose, Martinez‐said, Hector, Medina‐franco, Heriberto, Mendez, Manuel, Suárez Ma, Teresa Moreno Y, Díaz, Dolores Orta, León Vázquez, Martha Patricia Pérez, Carvajal, Angélica Azucena Soto, Hernández, Fidel Soto, Stenner, Juan Ignacio, López, Adriana Valenzuela, Hernandez, Mauricio Rene, Romero, Rey Jesus, Hernandez, Aldo Bernal, Cortes‐flores, Ana Olivia, Valle, Carlos Jose Zuloaga Fernandez, Tinajero, Carlos Andres Colunga, Orozco‐perez, Jaime, Balboa, Laura Gabriela Peña, Yanowsky‐reyes, Guillermo, Torres, Víctor Hugo Alcalá, Camacho, Francisco José Barbosa, Perez, Irma Valeria Brancaccio, Calderon‐llamas, Miguel Angel, Gomez, Aldo Camacho, Cortes‐torres, Edgar‐joaquin, Cueva‐martinez, Esteban, Anguiano, Oscar Durán, Estrada, Isaac Esparza, Fierro‐rizo, Roberto, Becerril, Paola Flores, Orozco, Clotilde Fuentes, Castillo, Miguel García, Ojeda, Alejandro Gonzalez, Rubio, Ana Sofia Gonzalez, Rojas, Erick Alonso González‐García, Govea‐camacho, Luis Humberto, Barba, Jose Aldo Guzman, Peña, Juan Carlos Ibarrola, Martínez, César íñiguez, Llamas‐macias, Francisco Javier, Galaviz, Ruben Eduardo Morán, Nuño‐escobar, Cesar, Olvera‐flores, Oscar‐everardo, Osuna‐rubio, Jaqueline, Pérez‐navarro, Jose Victor, Prieto‐aldape, Rodrigo, Gonzalez, Luis Ricardo Ramirez, Sánchez, Marco Vinicio Ramírez, Reyes, Emilio, Romero‐limón, Olaya Moramay, Ruiz‐velasco, Carlos Beas, Martínez, José Antonio Sánchez, Sanchez‐villaseñor, Guillermo, Sedano‐portillo, Ismael, Gonzalez, Gabriela Ambriz, Moreno, Pedro Berrones Moreno Berrones, Alvarado, Ana Beatriz Calderon, Jesús Cárdenas Barón, José, Hernández, Araceli, Frutos, Francisco Javier León, Hernandez, Edgard Efren Lozada, Valencia, Eduardo Morales, Pérez, Karla Daniela, Bolanos‐morales, Francina, Herrera‐zamora, Julio, Santillan‐doherty, Patricio, Zavala, David Omar Arriaga, Campos, Salvador Francisco Campos, Carmona, Lizette, Nava, Antonio Galindo, Santos, Blanca, Cisneros, Juan Roberto Torres, Bozada‐gutiérrez, Katya, Herrera, Jose Jesus, Portillo, Mucio Moreno, López, Francisco Pérez, Trejo‐avila, Mario, Salazar, Carlos Valenzuela, Alvarez, Maria Regina, Cordera, Fernando, Rosa Abaroa, Marco Antonio, Gómez‐pedraza, Antonio, Hernandez, Roberto, Maffuz‐aziz, Antonio, Posada, José Antonio, Vidal, Carlos Robles, Beristain‐hernandez, Jose‐luis, Sada, Blas Eduardo Quintero, Heredia, Nicolás Uxmal Soruco, Anaya, Ernesto, Arceo‐olaiz, Ricardo, Sougarret, Bernardo Gutiérrez, Flores, Sonia Lopez, Ochoa Carrillo, Francisco J., Uribe, Raymundo Alfredo Pérez, Silva, Ludwigvan Adriano Bustamante, Lupián‐angulo, Arianne I, Martínez, Christian Enrique Soulé, García, Francisco César Becerra, Casillas, Ernesto Javier Guerrero, Uribe, Edgar, Arias, Nereida Esparza, Hernández‐nava, J. Mindy, Isla‐ortiz, David, Melchor‐ruan, Javier, Bañuelos, Esmeralda Romero, Salcedo‐hernández, Rosa, Vilar‐compte, Diana, Peniche, Paola Zinser, Aguilar Frasco, Jorge L., Alfaro‐goldaracena, Alejandro, Buerba, Gabriela Alejandra, Castro, Emma, Chan, Carlos, Cortes, Ruben, Dominguez‐rosado, Ismael, Lechuga, Daniel Garay, Herrera, Miguel, Hinojosa, Carlos, Lopez‐pena, Gabriel, Martos, Edgar, Mercado, Miguel ángel, Velázquez, Paulina Moctezuma, Moguel, Roberto, Oropeza, Mariano, Portugal, Emmanuel Peña Gómez, Posadas‐trujillo, Oscar Emmanuel, Salgado‐nesme, Noel, Jasso, Oscar Santes, Sarre, Catherine, Skewes, Karla Yareli Hernandez, Jimenez, Cristian, Licona‐meníndez, Roque Delfino, Montiel, Guillermo, Navarrete‐peón, Alberto, Ortega, Shannat, Lechuga, Fernanda Romero, Roque, Oscar, Sevilla, Fernando, González‐lópez, Rogelio, Núñez‐gonzález, Roberto ángel, Ortega‐jiménez, José Antonio, Alvarado, Antonio, Orendain, Alfonso Alvarez Manilla, Pesquera, José Alberto Atristain, Frutos, Diego, Garcia, Felipe, León, Juan Antonio González, Guzman, Marlin, Herappe, Dorihela, Miranda, Jesús Giovanni Inzunza, Botello, Miguel Angel Jimenez, Lerma, Ricardo, Pedraza, Fabián Hilario Mendoza, Castillo, Monica Noguez, Resendiz, Jose Anatolio, García, Oscar Alejandro Sánchez, Rios, Laura Elena Fernandez, Frigerio, Pamela, Garcia, Iset, Frías, Gloria Isela Mendoza, Moreno, Emmanuel, Quiroga, Raquel, Mendoza, Alejandra Anzures, Hinojosa, Arantza Govela, Izaguirre, Aldo, Miguelena, Luis Hdez, Vazquez, Jose Manuel Luna, Rodriguez, Indalecio Barcelata, Mange, Raul Ramos, Utrera, Carlos Reyes, Saenz, David Zarate, Gonzalez, Miguel Angel Zavala, González, Francisco Andrade, Cortes, Ludivina, Roman, David, Sanchez, Aaron, Gurghiș, Radu, Rojnoveanu, Gheorghe, Vozian, Marin, Caraja, Petru, Croitor, Gheorghe, Mosneaga, Roman, Erdene, Sarnai, Ganbold, Lundeg, Orgoi, Sergelen, Orsoo, Soyombo, Sainbayar, Altanchimeg, Sandag, Erdene, Sanjaa, Burmaa, Benhamou, Rita Ait, El Azhari, Abdessamad, Ghita, Bennis, Lhassani, Sara, Louraoui, Sidi Mamoun, Rghioui, Mounir, Saaf, Sarra, Gadouali, Taha, Gouazar, Iltimass, Korch, Moniba, Letrache, Ahmed, Louari, Amina, Zamame, Anas, Ousouss, Samia, Zekhnini, Meryem, Abderrazaq, Hafni, Abichou, Wijden, Ahlaou, Hamza, Baicha, Amal, Baroudi, Salma, Chaoui, Ghita, El Azzazi, Hind, El Masaoudi, Saja, Hassoun, Chiraz, Moujtahid, Hajar, Riyahi, Anas, Zaim, Ouijdane, Aji, Narjiss, Ammouze, Imane, Arkha, Yasser, Bechri, Hajar, Belabbes, Meryem Benchekroun, Benslimane, Zaineb, Boualila, Lina, Bouanani, Othmane, El Ouahabi, Abdessamad, Hossyni, Leila Essakalli, Malik, Boulaadas, Oudrhiri, Mohammed Yassaad, Sefrioui, Taha Ismail, Tagmouti, Adam, Bensghir, Mustapha, Elkoundi, Abdelghafour, Belarabi, Othman, Belkhadir, Zakaria Houssaïn, Benkabbou, Amine, Boutayeb, Saber, El Ahmadi, Brahim, El Bouazizi, Yassine, Ghannam, Abdelilah, Kabbaj, Taha, Majbar, Anass Mohammed, Mohsine, Raouf, Souadka, Amine, Kone, Badra Aliou, Ndatewapo, Fillipus, Njuki, Peter Ngungi, Abrahams, Jenevive, Jeketera, Clara, Yeboah, Kwasi, Abebrese, John Tabiri, Mureko, Alfred, Quayson, Francis William, Shikongo, Justina, Bhusal, Subarna, Dwa, Yam, Joshi, Ashoo, Berkeveld, Eva, Bloemers, Frank, Borgstein, Alexander, Gisbertz, Suzanne, Mikdad, Sarah, Berge Henegouwen, Mark, Bakx, Roel, Besselink, Marc, Lemmers, Daniel HL, Roelofs, Anne‐jasmin, Amstel, Paul, Helsdingen, Claire, Smeele, Ludi, Harlaar, Niels, Jonker, Frederik, Burg, Sjirk, Oostendorp, Justin Y., Ombashi, Saranda, Voort, Tim, Geldorp, Martijn, Posma‐bouman, Lisanne, Boer, Hans Donald, Olieman, Annette, Smid‐nanninga, Henriette, De Vries, Jean‐Paul P. M., Hogenbirk, Rianne, Derksen, Tyche, Franken, Josephine, Oosterling, Steven, Nolte, Peter, List, Jelle, Alwayn, Ian, Bijlstra, Okker, Braat, Andries, Bulder, Ruth, Kok, Michèle, Faber, Robin, Goudsmit, Ben, Hamming, Jaap, Mieog, Sven, Vahrmeijer, Alexander, Leemkolk, Fenna E. M., Vorst, Joost, Schaik, Jan, Verhagen, Merel, Albers, Kim, Gawria, Larsa, Van Goor, Harry, Warle, Michiel, Ginhoven, Tessa M., Viëtor, Charlotte, Boerma, Evert‐jan, Lallitsch, Lara, Schweitzer, Donald, Leclercq, Wouter, Sijmons, Julie, Vancoillie, Peter‐jan, Konsten, Joop, Heinsbergen, Maarten, Dekker, Nicole, Boer, Frank, Dimech, Julian, Djamali, Kaveh, Fowler, Carolyn, Ghamri, Naji, Houston, Helen, Joseph, Reece, Kantroo, Astha, Kwun, Jin, Lie, Samuel, Lightfoot, Nicholas, Maccormick, Andrew, Olliff, Sue, Trilokekar, Natasha, Wood, Daniel, Ekanayaka, Aruna, Furkert, Chris, Nanayakkara, Asanga, Panesar, Divyansh, Waddell, Oliver, Bidois, Lauren, Clifford, Zoe, Frizelle, Frank, Glyn, Tamara, Lim, Eric, Lyons, Oliver, Mclauchlan, Jared, Nicholas, Ella, O’Grady, Michael, Roake, Justin, Singh, Harsh, Ailabouni, Ramez, Rietveld, John, Alqassab, Mohammed, Amer, Mostafa, Chan, Annie, Egbuji, John, Fullarton, Mairi, Haddow, James, Hawkins, Robyn, Vui Teck, Lu, Oliver, Thomas, Saw, Kai Sheng, Sugunesegran, Ramanen, Wilkins, James, Woodfield, Esther, Baker, Joseph, Cama, Jitoko, Field, Xavier, Fulivai, Alamea, Hossain, Ruhella, Kelly, Ben, Jasen, Ly, Mckelvie, James, Meiyappan, Vivek, Cindy Xin Yi, Ou, Singh, Vidit, Hedley, Alex, Temara, Hinerangi, Aitken, Jake, Frunt, Brytt, Boys, Max Hardie, Lakshman, Prashant, Pinfold, Esther, Cowan, Sarah, Henderson, Nigel, Leary, Jessica, Castle, Cameron, Gaston, Matt, Haimona, Maira, Jury, Steffanie, Lahood, Zoe, Lim, Matthew, Macintyre, Dillon, Mak, Josephine, Neal, Annelise, Shelker, William, Weeratunga, George, Ferguson, Liam, Harmston, Christopher, Heaven, Chelsea L, Watt, Imogen, Cahill, Henry Witcomb, Abdurrazzaaq, Abdussemee, Abdussalam, Hameedat Opeyemi, Adebanjo, Ademola, Ahmed, Aminat Olayinka, Borokinni, Opeyemi Busayo, Fasiku, Olushola Kayode, Gwaram, Usman, Okoye, Onyedika, Olaomi, Oluwole, Adeyeye, Ademola, Enoch, Elizabeth, Fayose, Samuel, Kayode‐nissi, Victor, Kadiri, Innih, Oduah, Stella, Abdull, Mohammed, Abdullahi, Mohammed Kabir, Kwankiyel, Auwal Babayo, Umar, Shahir Bello, Hassan, Sulaiman, Ja’Afar, Abubakar Bappah, Ja’Afaru, Umma Hani, Kadas, Saidu, Liman, Haruna, Makama, Baje, Mohammad, Aminu Mohammad, Kirfi, Abdullahi Musa, Oyediji, Funmilayo, Mohammed, Husseini Yakubu, Akpoghor, Oghenevwegba, Arekhandia, Alexander, Dawodu, Oseyi, Edetanlen, Ekaniyere, Efobi, Chizoba, Egbor, Esezobor, Enaruna, Nosakhare, Ezeanochie, Michael, Ezenwa, Ekene, Ijekeye, Ferdinand, Imumoren, Joe, Iribhogbe, Oseihie, Irowa, Omorodion, Momoh, Moses, Nwashilli, Nnamdi, Obahiagbon, Osarobo, Obuekwe, Ozoemene, Odai, Emeka Danielson, Odigie, Vincent, Odutola, Oluwatomi, Okhakhu, Amina, Okugbo, Stanley, Oni, Samson, Onyeagwara, Ngozi, Oseghale, Eustace, Osemwegie, Osarenkhoe, Osho, Philip, Ugwi, Veronica, Uwagboe, Charles, Yusuf, Sofiat, Abiodun, Adekunle, Akinloa, Olufemi, Shodipo, Moses, Abdullahi, Alhassan, Lawal, Ishak, Echieh, Chidiebere Peter, Nwagboso, Chimaobi, Udoh, Ubong, Akanni, Bolaji, Anyimba, Solomon, Chukwu, Isaac, Ezomike, Uchechukwu, Gold, Ikponmwosa, Nnabugwu, Ikenna, Nwafor, Ikechukwu, Okolie, Louis, Okoro, Kelechukwu, Okwara, Blasius, Onyemaechi, Ndubuisi, Abdulsalam, Khalifa, Arogundade, Abayomi, Kura, Mohammed, Nwosu, David, Abdullahi, Habiba, Agida, Eyaofun, Aisuodionoe‐shadrach, Oseremen, Ajibola, Hafees, Akaba, Godwin, Ale, Omolabake, Atim, Terkaa, Emeka, Malachy Ayogu, Benard, Adeka, Buba, Amina, Chinda, John, Edino, Stephen, Eniola, Sefiu, Garba, Stephen, Isah, Aliyu, Isah, Dennis Anthony, Joshua, Zaman, Mbajiekwe, Ndubuisi, Mshelbwala, Philip, Muhammad, Rafat, Offiong, Richard, Olute, Anne, Osagie, Olabisi, Ogolekwu, Idoko Pius, Sulaiman, Bilal, Suleiman, Salisu, Umar, Aminu, Abayomi, Olukayode, Abdus‐salam, Rukiyat, Adebayo, Sikiru A., Adeleye, Amos, Ademola, Samuel, Afuwape, Oludolapo, Ajao, Akinlabi, Akinsola, Sanusi, Aladelusi, Timothy, Ayandipo, Omobolaji, Baiyewu, Lateef Ayodele, Balogun, Mosimabale, Daodu, Israel, Egbuchulem, Ifeanyichukwu Kelvin, Elemile, Peter, Ezeme, Constantine, Fasunla, Ayotunde James, Gbolahan, Olalere, Iwuagwu, Ifeanyi, Michael, Afieharo, Morhason‐bello, Jemiludeen, Nwaorgu, Onyekwere, Obadan, Izegaegbe, Odeyemi, Olubunmi, Ogundoyin, Omowonuola, Ogundoyin, Olakayode, Ogunkeyede, Segun Ayodeji, Ogunrewo, Tolulope, Okere, Oghenekevwe, Oladejo, Titilola, Oladiran, Ajibola, Olagunju, Naomi, Olaoye, Ifedolapo, Olawoye, Olayinka, Olulana, Dare, Olusanya, Adeola, Omigbodun, Akinyinka, Onakoya, Paul, Orji, Mathias, Oyelakin, Oyeleye, Oyewole, Olugboyega, Sule, Samuel, Takure, Augustine O, Ugwu, Ebere, Afolabi, Bosede, Ajayi, Peter, Akinajo, Opeyemi, Alakaloko, Felix, Atoyebi, Oluwole, Belie, Orimisan, Bode, Chris, George, Ihediwa Chibuike, Elebute, Olumide, Ezenwankwo, Francis, Fatuga, Adedeji, Ladipo‐ajayi, Oluwaseun, Makanjuola, Ayomide, Makwe, Christian, Mofikoya, Bolaji, Ohazurike, Ephraim, Ojewola, Rufus Wale, Okunade, Kehinde, Okunowo, Adeyemi, Olajide, Thomas Olagboyega, Oni, Oluwafemi, Tijani, Kehinde, Ugburo, Andrew, Ugwu, Aloy Okechukwu, Abiola, Paul, Abiyere, Henry, Adebara, Idowu, Adeniyi, Adebayo, Adeyemo, Olabisi, Ariyibi, Abimbola, Babalola, Olakunle, Bakare, Adewumi, Banjo, Oluseyi, Egharevba, Peter, Obateru, John, Ojo, Owolabi, Olajide, Adewale, Oluwafemi, Fatudimu, Oyeleye, Oluwole, Salawu, Adedayo, Babatunde, Bakare Tajudeen Ishola, Abdulsalam, Moruf, Adelaja, Aderinsola, Adeniran, Abimbola, Ajai, Olalekan, Atobatele, Kazeem, Ayodele, Olabamidele, Bello, Funmi, Faboya, Omolara, Idowu, Olufemi, Idowu, Jeuel, Mustapha, Muntaqa, Omisanjo, Olufunmilade, Osuoji, Roland, Vitowanu, Julius, Abe, Anthonia, Aderounmu, Adewale, Adesunkanmi, Abdulhafiz, Ajekwu, Temitope, Ajekwu, Samuel, Ajiboye, Olalekan, Aderogba, Adeleke Akeem, Alatise, Olusegun Isaac, Babatunde, Mustapha, Balogun, Simon, Ijarotimi, Adebimpe, Lawal, Adedayo, Ojo, Olugbenga, Olasehinde, Olalekan, Olugbami, Adebayo, Ubom, Akaninyene Eseme, Agbaje, Ademola, Mohammed, Tajudeen, Adeniran, Abiodun, Adesola, Muideen, Afolabi, Abdulrahman O., Aremu, Isiaka, Ayinmode, Iyehunwa, Bello, Jibril, Ezeoke, Grace, Gwadabe, Sadiya, Ibraheem, Gbadebo, Ibrahim, Saidu, Ijaiya, Munir’Deen, Nasir, Abdulrasheed, Odeyemi, Peter Olalekan, Ogunade, Olukayode, Olabinjo, Afusat, Olatoke, Samuel Adegboyega, Olowogbayi, Tope, Onjefu, Stephen, Popoola, Ademola, Raji, Hadijat Olaide, Salawu, Nasiru, Salawu, Hafeez, Sayomi, Tolulope Olayinka, Segun‐busari, Segun, Uche‐okonkwo, Kenechukwu, Abiola, Olajide, Anipole, Olalekan, Ogunlaja, Olumuyiwa, Adesina, Oluwaseyi, Alayande, Barnabas, Ebenezer, John, Enwerem, Kenneth, Isichei, Christian, Isichei, Mercy, Luku, Pwaluke, Omiragi, Paul, Onyeji, John, Adze, Joel, Aghadi, Ifeanyi, Auta, Akawu, Duniya, Sharon, Gyuro, Joseph, Lawal, Jamila, Makama, Jerry Godfrey, Mohammed, Garba, Mohammed‐durosinlorun, Amina, Salisu, Kabiru, Taingson, Matthew, Yusuf, Nuhu, Amos, Happy, Daniel, James, Takai, Idris Usman, Abdullahi, Lawal, Abdullahi, Sani, Abdulrahman, Mamuda, Abubakar, Mohammed Kabir, Adikaibe, Valentine, Ahmad, Misbahu, Ahmad, Jameel Ismail, Aji, Sani Ali, Aliyu, Mohammed Salele, Danagundi, Maryam Babba, Bako, Yusuf Halidu, Bello‐muhammad, Nafisatu, Garzali, Ibrahim Umar, Hasheem, Muhammad Ghazali, Hassan, Ismail, Hassan, Sadiq, Usman, Mustapha Ibrahim, Ismail, Nasiru, Jibril, Yasir Nuhu, Kurawa, Musbahu, Magashi, Mahmoud Kawu, Martins, Bardi, Bello, Usman Mohammed, Muhammad, Saminu, Muhammad, Abubakar Bala, Muhammad, Shamsuddeen, Daneji, Sulaiman Muhammad, Mukhtar, Ibrahim Aliyu, Adamu, Kabir Musa, Nwachukwu, Callistus, Omeje, Uchenna Kelvin, Orji, Ifeanyi James, Sheshe, Abdurrahman Abba, Suleiman, Ibrahim, Yunusa, Sani Abdullahi, Maryam, A, Abubakar, Kabiru Bello, Habib, Saudat Garba, Mahmood, Farrukh, Alabi, Ibrahim Abolaji, Arojuraye, Soliudeen, Salihu, Mohammed, Alade, Samuel, Kumolalo, Felix, Mogbo, Chiedozie, Adebayo, Olaolu, Ige, Oluwasuyi, Jones, Gbenga, Odunafolabi, Tunde, Olubayo, Oluniyi Oyetunde, Akani, Chris, Alasia, Datonye, Alegbeleye, Justina Omoikhefe, Aria, Oti Nimi, Awopeju, Abimbola, Edonkumoh, Kemebradikumo, Ekeke, Onyeanunam, Fyneface‐ogan, Sotonye, John, Celestine, Kasso, Terhemen, Korubo, Inye, Mato, Christie, Ogu, Rosemary, Okpani, Charles, Okpani, Anthony, Onwuagha, Ijeoma, Oppah, Ijeoma, Oputa, Victory, Oranu, Emmanuel, Orazulike, Ngozi, Otokwala, Job, Ugboma, Henry A. A, Ajayi, Adekunle, Ogundele, Ibukunolu, Salami, Babatunde, Ajagha, Okeoghene, Ali, Yakubu, Awaisu, Mudi, Daniyan, Muhammad, Fidelis, Lovely, Nwabuoku, Stanley Emeka, Ogunsua, Oluseyi, Oyelowo, Nasir, Sholadoye, Tunde T., Yakubu, Alfa, Rendevski, Vladimir, Shuntov, Blagoj, Shuntov, Natalija Cokleska, Georgieva, Gordana, Jovanoski, Tomislav, Jovanovska, Katerina, Nikolovska, Bisera, Peev, Igor, Srbov, Blagoja, Trajkova, Andrijana, Trenchev, Viktor, Dohcev, Sasho, Janchulev, Josif, Saidi, Skender, Stankov, Oliver, Trifunovski, Aleksandar, Draz, Najib Abu, Al Ajmi, Khalil, Al Ajmi, Ghadeer, Al Amri, Ayman, Al Badaai, Ghalib, Al Balushi, Nawf, Al Bassam, Wameedh, Al Farsi, Maather, Al Ghafri, Wadha, Al Ghafry, Alaa, Al HOSNI, Mohammed, Al Kalbani, Moza, Al Kalbani, Maha, Al Kharusi, Lamya, Al Kharusi, Safiya, Al Mutani, Mohammed, Al Qadhi, Hani, Al Raisi, Amani, Al Riyami, Nihal, Al Sabti, Hilal, Al Shaibi, Maha, Al‐abri, Rashid, Al‐mujaini, Abdullah, Al‐rashdi, Aya, Alajmi, Suha, Albadi, Zamzam, Albusaidi, Hanadi, Alhadeethi, Ahmed, Aljabri, Noor, Alkazrooni, Muhannad, Alkharousi, Nadiya, Alkharusi, Al‐salt, Alkiyumi, Khadija, Almaharbi, Noof, Alsaadi, Sabaa, Alsharji, Marwa, Alsharqi, ALi Hamed, Alshehhi, Fatma, Alsulaimani, Thuwaiba, Alward, Mustafa, Alwashahi, Mohammed, Alyafii, Hussain, Alzadjali, Adil, Basi, Tayseer, Dalmar, Khadija, Dawud, Bashar, Gargouri, Mohamed Mourad, Kariyattil, Rajeev, Kenawy, Ahmed Omer, Kochummen, Koshy, Kolethekkat, Arif, Pillai, Mahesh Krishna, Sureshkannan, Ks, Laghari, Farman Ali, Manjunatha, Attibele Palaksha, Mathew, Joseph Kunju, Muzaffar, Rahil, Nair, Asha, Naiya, Hafsa Ismail Ibrahim, Nazar, Zuhail, Pillai, Silja, Rahim, Ferdous, Rahman, Khalid, Sheik, Shahila, Siddiqi, Mohammad Salman, Stephen, Edwin, Younas, Shahzad, Fatima, Mishal, Javed, Ayesha, Khan, Muhammad Ahsan, Shakir, Fatima Tuz Zahra, Siddiqui, Riaz Hussain, Syed, Danish, Rehman, Ishtiaq Ur, Warraich, Shahrukh, Amir, Mohammed, Asghar, Saleha Yurf, Bangash, Ali Haider, Latif, Sehrish, Naqvi, Wajih, Abdullah, Muhammad Tariq, Abdullah, Saleha, Ahmed, Arooj, Ahsan, Muhammad Fahim Ahsan, Akhtar, Fahad, Ali, Sana, Ansar, Mehwish, Aqib, Muhammad, Arslan, Muhammad, Ashraf, Sumaira, Ayubi, Azaz, Azam, Tayyab, Bhatti, Hamza, Huda, Shahab, Irshad, Abeer, Ishaque, Nazia, Khaliq, Tanwir, Khan, Farheen, Khan, Mumtaz Ahmad Khan, Mahmood, Namrah, Malik, Ali Raza, Malik, Tahir, Malik, Komail, Mehmood, Manzer, Mustafa, Fatima, Noor, Fazal, Nubair, Sarwar, Rashid, Isbah, Saeed, Waqar, Sajid, Hannan, Shah, Sajid, Shami, Ali, Siraj, Minhaj Us Siraj, Tareen, Mariam, Haq, M Burhan Ul, Abbas, Manzar, Zaidi, Syeda Maria Ahmad, Ahmed, Iffat, Ahmed, Shahnoor, Ahsan, Kunwar Armash, Akhtar, Munazza, Akhund, Ramsha, Manji, Adil Al‐Karim, Arshad, Hajra, Awan, Muhammad Ozair, Aziz, Humaira, Bhutto, Shameen, Aamir, Faiqa Binte, Biyabani, Syed Raziuddin, Chishti, Uzma, Chundrigar, Mohsin, Ghaloo, Shayan Khalid, Haroon, Waqqas, Hashmi, Shiraz, Hassan, Murtuza, Inam, Hina, Kassam, Nausheen, Kazmi, Abbas, Khan, Majid, Khan, Muhammad Osama, Kumari, Sameeta, Malik, Muhammad Jehangir, Mansoor, Maheen, Martins, Russell Seth, Mubarik, Areeba, Munir, Muhammad Musaab, Musharraf, Muhammad Bazil, Naz, Falak, Noordin, Shahryar, Pervaiz, Arsalan, Qamar, Javeria Bilal, Rahman, M Fazlur, Rani, Pallavi, Rasheed, Yasir, Sadia, Haleema, Saeed, Marwah, Safri, Mohammad, Salim, Shaharyar, Sattar, Abida K., Shamim, Shahzad, Sherwani, Maryam, Siddiqui, Muhammad Ahsan Iqbal, Sidhwa, Astad, Tariq, Javeria, Tejani, Isbaah, Waqar, Usama, Zahid, Fahad, Jamal, Abid, Ghufran, Muhammad Ali, Memon, Amjad Siraj, Saeed, Summaya, Samo, Khursheed Ahmed, Aswani, Manisha, Manzoor, Shahneela, Muhammad, Shoaib, Arshad, Muhammad, Hussain, Syeda Namayah Fatima, Moin, Inshrah, Najjad, Muhammad Kazim Rahim, Nasir, Manal, Sohail, Osama Bin, Mangi, Ali, Markhand, Naveed, Mushtaq, Hassan, Zia, Kashif, Ahmed, Hassaan, Ahmed, Nasir, Qureshi, Talha Ahmed, Shaikh, Shafqat Ali, Anwer, Rabia, Arshad, Owais, Batool, Sehrish, Chatni, Muhammad, Chundrigar, Tariq, Dojki, Samina Saleem, Elahi, Minahil, Farooqui, Bakhtawar, Ghouri, Amna, Hassan, Nabeel, Hussain, Zainab, Hussaini, Null, Iftikhar, Fizza, Iqbal, Faizan, Javed, Anum, Javed, Dania, Kamal, Wajahat, Khan, Shifa, Mughal, Zeeshan Uddin, Murtaza, Ghulam, Nadeem, Areeba, Nasir, Areeba, Nayyer, Fatima, Nisa, Kanwal, Rauf, Yaseen, Haroon, Umer Saeed, Saleem, Shah Masabat, Seriwala, Haseeb, Shah, Aaqil, Siddiqui, Safia, Tanveer, Asher Tanweer, Tariq, Nida, Zaman, Junaid, Zamir, Mehroz, Anjum, Muhammad Ayyub, Afzal, Ameer, Ahmed, Ehsan, Ahmed, Jawad, Riaz, Shujat Ahmed, Akbar, Ali, Akbar, Bilal, Ali, Maria, Ali, Imran Ali, Ali, Abrar Ashraf, Ali, Ghazanfar, Altaf, Zahra, Ammar, Ahmed Siddique, Arif, Hafiz Muhammad Arif, Aslam, Imran, Bashir, Muhammad Mustehsan, Farooq, Usman, Farooq, Muhammad, Gondal, Khalid Masood, Iqbal, Muhammad Javed, Iqbal, Zafar, Ismail, Fahad, Jameel, Muhammad Khurram, Janjua, Muhammad Haris, Janjua, Azwa, Joshi, Prabesh, Khadam, Mamoona, Khan, Romaisa, Khawaja, Muhammad Asadullah, Manzoor, Sobia, Mohsin, Muhammad, Mumtaz, Khizra, Musaab, Muhammad, Naqi, Syed Asghar, Naumeri, Fatima, Nazir, Umer, Noureen, Sadaf, Rafi, Yaseen, Raza, Ali, Rijal, Sushil, Saleem, Irfan, Shah, Hafiz Syed Zaigham Ali, Sharif, Muhammad, Shaukat, Ayesha, Siddique, Usman, Sikandar, Hafiz Saqib, Sohail, Mohammad, Zahara, Fatima Tu, Usman, Yasmeen, Zaman, Balakh Sher, Zeb, Misbah, Afzal, Muhammad Farooq, Ahmad, Fateen, Ahmed, Waqas, Akram, Shahzad, Alam, Azhar, Ali, Danish, Ali, Ahsan, Alvi, Ammar Tariq, Asif, Suleman Asif, Aslam, Madiha, Daood, Muhammad Daood, Jawad, Muhammad, Kathia, Usama Muhammad, Khalid, Ismaeel, Khan, Anwar, Khurshid, Zain, Noman, Hamza, Raza, Ahsan, Taha, Hassan, Zubair, Muhammad, Maria, Noor Ul Huda, Janjua, DrAtif A, Ahmad, Qamar Ashfaq, Ahmad, Sheraz, Ali, Imran, Amin, Sana, Anjum, Momina, Asjad, Muhammad, Aslam, Aatif, Ayyaz, Mahmood, Bajwa, Luqman Ali, Bakhtiar, Akkasha, Bashir, Alia, Batool, Fizza, Bhatti, Samiullah, Butt, Roshan, Butt, Usman, Changazi, Shabbar Hussain, Cheema, Omer Iqbal, Chishti, Muhammad Haris, Haq, Bushra, Hashmi, Ali, Hassan, Muhammad, Hassan, Usman, Hayat, Khizar, Iqbal, Javaid, Iqbal, Ayesha, Ishaq, Amna, Javed, Sundas, Javed, Hina, Javed, Aymen, Kashif, Muhammad, Khalid, Muhammad Saud, Khan, Wasim Hayat, Khan, Rohma, Khan, Fatima, Latif, Usman, Mahmood, Arif, Majeed, Faizan, Malik, Kiren, Masood, Rumaisa, Munawwar, Fasiha, Mushtaq, Asma, Nabi, Muhammad Shoaib, Nasir, Ahmad, Naureen, Shazia, Noreen, Zahida, Qadir, Muhammad Ghulam Qadir, Raana, Gul e Raana, Rashid, Madeeha, Rehman, Abdul, Riaz, Sidra, Saboor, Arfa, Sadiq, Muhammad Hamza, Saeed, Komal, Saleem, Humaira, Sarfraz, Kiran, Shafiq, Zahid, Shafqat, Aymen, Shaukat, Hassan, Sher, Fateh, Sohail, Rubina, Suhail, Amina, Muhammad, Bilal Syed, Umair, Usama, Umar, Muhammad, Usama, Muhammad, Usman, Natasha, Waheed, Kalsoom, Farooka, Muhammad Waris, Wasim, Shafqat, Wasim, Tayyiba, Yasin, Fahad, Zafar, Zain, Zaka, Sabahat, Zaman, Salma Zaman, Azad, Junaid, Fatima, Zareen, Anwar, Muhammad Imran, Naseer, Muhammad Ahmed, Shah, Muhammad Taimoor, Ali, Ammar, Aslam, Muhammad, Aziz, Muhammad Usama, Gohar, Farhan, Humayoun, Waseem, Khan, Hassan, Naeem, Shiza, Tahir, Warda, Alvi, Kashif, Mehmood, Maria, Ali, Muhammad, Shahzad, Aniqa, Sher, Muhammad, Murtaza, Null, Siddique, Hijab, Anjum, Waleed, Ahmad, Manzoor, Alam, Muhammad, Faizi, Fouzia, Faridoon, Shehla, Hussain, Musarrat, Iftikhar, Muhammad, Jan, Yousaf, Kalim, Muhammad, Raza, Tilal Ahmed, Shah, Farrukh Ozair, Shah, Muhammad, Tahir, Imran, Khan, Hamza, Naeem, Muhammad, Ahmad, Shabir, Ahmed, Haseeb, Akbar, Hazrat Akbar, Akhtar, Muhammad Shaheer, Ali, Noman, Ali, Mehboob, Ali, Sadaf, Ali, Irfan, Amin, Hasbi Allah, Amin, Shehzadi, Ayub, Bakhtawar, Basir, Muhammad, Faraz, Ahmad, Farsi, Muhammad Salman, Gul, Ambrin, Gul, Hina, Gul, Ayaz, Gul, Sana, Haider, Sajjad L, Ikramullah, Syed Ikramullah, Jan, Kashif, Khalid, Muhammad, 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(INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), GlobalSurg Collaborative, Surgery, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Graduate School, AGEM - Endocrinology, metabolism and nutrition, ARD - Amsterdam Reproduction and Development, Paediatrics, Tytgat Institute for Liver and Intestinal Research, Nepogodiev, D., Simoes, J. 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A., Workneh, W., Genetu, S., Mebratu, E., Chanyalew, L., Deresse, T., Girma, A., Seid, M., Shimelash, D., Shitaw, A., Ayalew, T., Diress, T., Kassahun, B., Kassaye, B., Mulugeta, E., Tesfaw, G., Yimenu, B., Benecha, S., Aman, M., Mekete, A., Tesemma, A., Mohammed, A. A., Abdullahi, Y. Y., Adem, E., Ahmedin, M., Assefa, Y., Ayde, F., Berhe, A., Gebremeskel, Z., Siyoum, E. G., Teresa, S., Wude, Z., Yemer, F., Yohannes, D., Zeleke, E., Zerihun, G., Degefe, D. W., Derilo, H. T., Eliyas, N., Bayissa, F., Deressa, Y., Gemechu, L., Gurmu, T., Kasaye, A., Melese, L., Muleta, L., Mulugeta, G., Taye, S., Teshome, A., Tesso, B., Gebrekirstos, G., Haile, M., Kassa, H., Saddik, M., Mengist, A., Heikkinen, J., Helminen, O., Huhta, H., Kotkavaara, T., Mosorin, M. -A., Pitkanen, J., Qian, C., Sinikumpu, J., Sova, H., Tastula, M., Virta, V. 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M., Salle, H., Taibi, A., Tricard, J., Usseglio, J., Chopinet, S., Gregoire, E., Delpont, M., Blanchard, C., Crenn, V., de Vergie, S., Denis, W., Fragnaud, H., Regenet, N., Rigaud, J., Varenne, Y., Anract, P., Barat, M., Biau, D., Dautry, R., Dohan, A., Idier, L., Lang, E., Thouny, C., Tzedakis, S., Audenet, F., Cazelles, A., Chamouni, A., Karoui, M., Mejean, A., Clermidi, P., Langlais, T., Leonelli, L., Maisonneuve, E., Nicolas, B., Perrot, O., Prost, D., Thomin, A., Thouement, T., Athiel, Y., Berry, R., Boddaert, G., Bonnet, S., Cathala, N., Conso, C., Denet, C., Laforest, A., Levy-Zauberman, Y., Macek, P., Mombet, A., Ollat, D., Scamporlino, A., Zadegan, F., Amine, C. A., Baratte, B., Chartier-Kastler, E., Chereau, N., Colas, P. -A., Duquesne, I., Genser, L., Petit, G. 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A., Asaph, E., Baruwa, E., Hofman, G., Machemedze, S., Idiata, M. M., Muhemi, R., Ndizeye, O., Nkunzimana, E., O'Connor, J., O'Connor, Z., Tchoba, S., Boumas, N., Devidze, G., Pisarevi, G., Baumgarten, S., Grusser, L., Holzle, F., Kowark, P., Kowark, A., Rossaint, R., Schafer, B., Wallqvist, J., Winnand, P., Ziemann, S., Anthuber, M., Broecheler, T., Edlinger, F., Gosslau, Y., Hyhlik-Duerr, A., Maksymiw, F., Shiban, E., Sommer, F., Sommer, B., Zerwes, S., Beyer, K., Lauscher, J. C., Lee, L. D., Loch, F. N., Schineis, C., Aghalarov, I., Belyaev, O., Braumann, C., Enste, A., Fahlbusch, T., Herzog, T., Horn, J., Jedanowski, J., Knipschild, J., Luu, A. M., Mohan, P. V., Siemen, L., Slobodkin, I., Strotmann, J. J., Uhl, W., Wolf, K., Coburn, M., Egger, E., Eichhorn, K., Enderes, J., Far, F., Franzen, A., Guresir, E., Hadjiathanasiou, A., Kalff, J. C., Kohistani, Z., Manekeller, S., Mustea, A., Probst, C., Randau, T., Recker, F., Schuss, P., Strassberger-Nerschbach, N., Strieth, S., Treede, H., van Beekum, C. J., Vatter, H., Velten, M., Vilz, T. O., Wirtz, D., Wittmann, M., Behr, M., Bulian, D. R., Marche, B., Moczko, T., Otchwemah, R., Schulz, S. -A., Thomaidis, P., Bruns, C., Cursiefen, C., Domrose, C., Fuchs, H., Heindl, L. M., Mallmann, M. R., Mallmann, C., Ratiu, D. A., Canzler, U., Distler, M., Korn, S., Meisel, C., Meusel, M., Petzold, A., Praetorius, C., von Renesse, J., Weitz, J., Wimberger, P., Alkhanji, N., Fung, S., Jaber, K., Knoefel, W. T., Vay, C., Clonda, O., Cottin, T., Juodiene, E., Juodis, D., Petrovic, B., Solodarenko, O., Binder, J., Grutzmann, R., Hackner, D., Junker, S., Arsalan, M., Banek, S., Chun, F., Faqar-Uz-Zaman, S. F., Keese, D., Kluth, L., Rolle, U., Van Linden, A., Walther, T., Bayer, J., Beck, J., Fung, C., Kraus, L. M., Leiber, C., Neidert, N., Sandkamp, R., Schnell, O., Schulte, A., Strahle, J., Jarmusch, S., Novotny, H. F. G., Becker, J., Fulghum, C., Gonschor, B., Herbolzheimer, M., Nicolaiciuc, S., Trulson, A., Vogelsang, H., Zimmermann, B., Akbari, A. A., Boening, A., Edinger, F., Hecker, M., Knitschke, M., Koch, C., Reichert, M., Schmidt, G., Schneck, E., Uhl, E., Nobrega, S. F., Kauffmann, P., Miller, C., Nemeth, M., Sievers, D., Kisser, U., Kleeff, J., Klose, J., Lorenz, K., Papendick, N., Plontke, S., Seiwerth, I., Steer, S., Thomssen, C., Ukkat, J., Dumpies, C. W., Gessner, M., Hanke, J., Klauke, F., Leuschner, S., Mendel, T., Muller, K., Schmidt, B., Schreiter, V., Stosberg, P., Vinz, F., Herbig, B., Sander, J., Schulte, T. M., Betz, C. S., Bewarder, J., Bier, J., Bottcher, A., Burg, S., Busch, C. -J., Bussmann, L., Gosau, M., Heuer, A., Izbicki, J., Klatte, T. O., Konig, D., Kopke, L. -G., Moeckelmann, N., Praetorius, M., Priemel, M., Stadlhofer, R., Stangenberg, M., Uzunoglu, F. 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V., Diamantis, A., Fichter, A., Grill, F., Heck, M., Jira, D., Kallmayer, M., Koll, F., Luhne, S., Meyer, B., Patachia, R., Pergolini, I., Safi, S., Schaffer, C., Schirren, M., Wegmann, H., Wirth, M., Zhu, Z., Aghamaliyev, U., Almaghrabi, M., Bocker, W., Bruder, J., Frank, K., Herterich, V., Huber, V., Ilmer, M., Kammerlander, C., Neuerburg, C., von Ehrlich-Treuenstatt, V. H., Werner, J., Borner, N., Fegg, F., Hartmann, D., Ladurner, R., Liokatis, P., Patzer, K., Schlager, J. G., Smolka, W., Zimmermann, P., Hatz, R., Steinhart, D., Glowalla, C., Schneidmueller, D., Henkel, K. W., Steiner, M., Holz, K., Knorr, C., Kuehlmann, B., Oikonomou, K., Prantl, L., Flurschutz, R., Honarpisheh, H., Kroger, M., Lepiorz, D., Luths, C., Niemeier, A., Sras, Y., Strate, T., Winter, T., Freiman, T., Gessler, F., Won, S. -Y., Widyaningsih, R., Hoffmann, S., Schafer, R. C., Thiel, J. T., Bertolani, E., Steidle, C., Uberruck, L., Yurttas, C., Ziegler, P., Zimmermann, A., Bolenz, C., Dayan, D., Greve, J., Hoffmann, T. K., Janni, W., Lobig, N., Schochter, F., Vahl, J. M., Wezel, F., Greif, V., Schmidbauer, S., Marsch, I., Schneider, R., Boenicke, L., Degener, S., Dreger, N. M., Horstmeier, F. C., Kruschwitz, J., Rombach, A., Schmidt, N., Seiberth, R., Singh, J., Smit, M., von Rundstedt, F. -C., Zirngibl, H., Diessner, J., Friedrich, S., Germer, C. -T., Helmer, P., Herrmann, J., Kranke, P., Kubler, H., Lock, J., Lotz, C., Meffert, R., Meybohm, P., Muller, S., Notz, Q., Popp, M., Schlegel, N., Schlesinger, T., Schmid, B., Sitter, M., Steinisch, A., Treutlein, A., van den Berg, A., Wurmb, T. E., Agyeman-Duah, N. K., Appiah, E., Armah, R., Asare, C., Awere-Kyere, L., Daary, D., Gakpetor, D., Allah, S. M., Obbeng, A., Osei-Poku, D., Puozaa, D., Tackie, E., Adu-Aryee, N. A., Agboadoh, N., Asare, O., Bowan, A. B., Brown, G. D., Clegg-Lamptey, J. -N., Dedey, F., Dery, C., Fenu, B. S., Harrison, M. A., Kumassah, P., Kuuzie, E., Nsaful, J., Olayiwola, D. O., Smith, C., Banka, C., Hussey, R., Azize, D. A., Aniakwo, L. A., Adofo-Asamoah, Y., Agbeno, E. K., Agyapong, M. M., Agyen, T., Mensah, K. A., Alhassan, B. A. B., Amoako-Boateng, M., Appiah-Thompson, P., Gyimah, N. A. -M., Asante-Bremang, M., Asante-Asamani, A., Atawurah, H., Appiah, A. B., Baidoo, R. O., Baidoo, E. I., Boakye, B., Boateng, A., Dadoe, D., Dayie, M. S. C. -J. K., Debrah, S., Doku, K., Enti, E., Ken-Amoah, S., Koggoh, P., Kpangkpari, R., Maison, P., Mensah, S., Mensah, P., Mensah, T. A., Morna, M. T., Nimako-Mensah, J., Nkrumah, J., Nortey, M., Ofori, E. O., Opandoh, I. N. M., Osei-Tutu, E., Adae, J. O., Quansah, K., Quartson, E., Rahman, G. A., Walawah, D., Yigah, M., Yussif, S., Jiagge, N., Nachelleh, E., Acquaye, J., Agbedinu, K., Agyei, F., Agyemang-Prempeh, A., Amo-Antwi, K., Amoah, M., Amoah, G., Amoako, Y. A., Aning, D. 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T. -A., Grypiotis, I., Kiriakopoulos, N., Koliopoulos, G., Kyvelos, V., Micha, G., Papadopoulou, T., Balalis, D., Fradelos, E., Korkolis, D., Alexakis, N., Angelou, K., Haidopoulos, D., Prodromidou, A., Rodolakis, A., Thomakos, N., Psychogios, D., Antonakis, P., Bramis, K., Chardalias, L., Contis, I., Dafnios, N., Dellaportas, D., Dimitra, P., Fragkoulidis, G., Gkiokas, G., Gklavas, A., Hadjizacharias, T., Karageorgou, D., Konstadoulakis, M., Kontopoulou, C., Massaras, D., Memos, N., Papaconstantinou, I., Politis, D., Polydorou, A., Stamatis, K., Theodosopoulos, T., Vezakis, A., Avgerinos, K., Katunin, J., Kechagias, A., Kelgiorgi, D., Kritikos, N., Pengerma, P., Bisdas, T., Ioannidis, A., Konstantinidis, M., Konstantinidou, S., Patelis, N., Antonopoulou, M. I., Deskou, E., Kalles, V., Manatakis, D. K., Stamos, N., Tasis, N., Arkadopoulos, N., Danias, N., Economopoulou, P., Frountzas, M., Kokoropoulos, P., Michalopoulos, N., Selmani, J., Sidiropoulos, T., Vassiliu, P., Paraskevas, K. I., Bartziotas, D., Bouchagier, K., Galanis, I., Kalamatianos, T., Kapiris, S., Kolinioti, A., Mavrodimitraki, E., Metaxas, P., Nikova, A., Psarologos, M., Sotiropoulou, M., Stranjalis, G., Albanopoulos, K., Kondilis, P., Vrakopoulou, G. Z., Chrysovergis, A., Chrysovitsiotis, G., Giotakis, E., Kanellopoulou, V., Kyrodimos, E., Larentzakis, A., Pantos, P., Papanikolaou, V., Potamianos, S., Theodoropoulos, C., Triantafyllou, A., Triantafyllou, T., Georgousi, K., Panagiotou, P., Avramidis, E., Babis, G., Zafeiris, E., Antoniou, A., Bessias, N., Maras, D., Papas, T., Roditis, K., Tsagkos, I., Tsiantoula, P., Alexandrou, A., Baili, E., Charalabopoulos, A., Dimitroulis, D., Dorovinis, P., Garoufalia, Z., Kanavidis, P., Karavokyros, I., Karydakis, L., Kykalos, S., Kyros, E., Machairas, N., Mastoraki, A., Nikiteas, N., Papalampros, A., Schizas, D., Skotsimara, A., Stamopoulos, P., Syllaios, A., Terras, A., Tomara, N., Tsourouflis, G., Vagios, I., Zografos, C., Apostolou, K., Georgopoulos, N., Antoniou, T., Antzaka, C., Falara, A., Fragoulis, S., Ftikos, P., Matsouka, F., Perreas, K., Rellia, P., Samara, E., Smirli, A., Tasouli, A., Thanopoulos, A., Chalkias, P. L., Dedemadi, G., Mourmouris, P., Skolarikos, A., Theochari, N., Tzelves, L., Gaitanakis, S., Milas, T., Theodorakis, E., Karona, P., Kastanaki, P., Tzouganakis, A., Agalianos, C., Tsouknidas, I., Xenakis, A., Chrysos, E., Lasithiotakis, K., Nikolouzakis, T., Xenaki, S., Xynos, E., Lostoridis, E., Nagorni, E. -A., Pujante, A., Tourountzi, P., Al, A., Baxevanidou, K., Bouliaris, K., Efthimiou, M., Kalfountzos, C., Koukoulis, G., Lachanas, V., Petropoulos, K., Tsitiridis, I., Angelis, F., Arnaoutoglou, E., Baloyiannis, I., Bareka, M., Bouronikou, A., Christodoulidis, G., Daponte, A., Fergadi, M., Gkolias, N., Gkrinia, E., Hajiioannou, J., Kalogritsas, N., Karoni, E., Korais, C., Krestinidis, G., Ktisti, A., Magouliotis, D., Maiou, C., Malizos, K., Minasidou, M., Ntalouka, M., Ntziovara, A. M., Palla, E., Perivoliotis, K., Saini, F., Samara, A., Saratziotis, A., Skoulakis, C., Solomi, E., Stamoulis, K., Terzoudis, C. D., Tsironi, E., Tzovaras, G., Vallianou, K., Zacharoulis, D., Ziogkou, A., Elias, L., Maroulis, I., Mulita, F., Plachouri, K. -M., Vailas, M., Doitsidis, C., Filo, E., Gkalonaki, I., Kogia, E., Kontopoulou, K., Mitroudi, M., Panteli, C., Patoulias, I., Semkoglou, O. I., Sfoungaris, D., Valioulis, I., Astreidis, I., Christidis, P., Ioannidis, O., Loutzidou, L., Mantevas, A., Paraskevopoulos, K., Tatsis, D., Athanasiadis, A., Dagklis, T., Kalogiannidis, I., Kapetanios, G., Mamopoulos, A., Margioula-Siarkou, C., Petousis, S., Tsakiridis, I., Anthoulakis, C., Christou, C., Fantakis, A., Iordanidou, E., Kaselas, C., Panagiotidou, S., Papadopoulos, V., Papavasiliou, K., Piachas, A., Siasios, I., Spyridakis, I., Theodoridis, T., Tooulias, A., Tsiridis, E., Tsopozidi, M., Aleman, M., Brolo, E., Lemus, A. L., Greenberg, J., Chew, K. M. M., Oliva, J. R., Lima, M. A. D. L., Muralles, I. L., Solares, F., Ajcip, G., Anton, C., Cojulun, J., Flores, M. -A., Jose, N., Paiz, C. A. M., Morales, S., Najera, R., Lorenzana, E. Q., Rivera, P., Rodas, L., Santos, V., Sosa, D., Ybarra, N., Cajti, J. D. P., Regil, C., Osorio, W. A., Arriola, R. R., Tale-Rosales, L. -F., Herrera, D., Rodriguez, S. T. T., Villeda, S. A., Anicetti, J., Medina, A. M. L., Ardebol, J., Barillas, K., De Leon, F., Recinos, S., Marroquin-Alpirez, M. -A., Yax, Y., Hon, S., Liu, Y. H., Liu, A. Q., Liu, S., Chiu, H. T. N., Chow, C. M. T., Hau, V., Ip, H. W., Mak, B., Mok, C. Y., Ng, D., Siu, Y. Y. E., Wong, K. F., Pu, J. J., Su, Y. -X., Au-Yeung, K. Y., Chan, D. Y. C., Chan, A., Chan, S. M., Chang, T. C., Chiu, T. W., Chiu, W. K., He, Z., Ho, M. F., Ho, K. K. W., Ho, J. Y. K., Kung, J. W. C., Lam, C. H., Lau, R. W. H., Ling, S. K. K., Lok, H. T., Mak, T. W. C., Ng, C. -F., Ng, S., Ng, K. K. -C., Ng, C. S. H., Ong, M. T. Y., Tan, T., Tang, S. F., Teoh, J. Y. -C., Teoh, A., Tsui, B. S. Y., Wong, G. K. C., Wong, R., Wong, K. C., Yee, C. H., Antal, Z., Kalman, A., Voros, P., Bahrehmand, K., Echim, T., Novak, Z., Sztipits, T., Bihari, L. A., Hidi, L., Piros, L., Rozsa, B., Sotonyi, P., Szatai, L., Herczeg, G., Pordany, B., Tornyi, F., Dede, K., Egyed, T., Saftics, G., Kulcsicka-Gut, J., Sipos, Z., Toth, D., Patel, B., Majmudar, H., Mankad, S., Pathan, S., Sharathkumarkl, L., Sasatti, L., Mahankali, S., Annayappa, S. K. S., Agrawal, T., Anandan, P., Baindur, A., Bd, M., Savitha, C., Anitha, G. S., Harigond, S., Tejeswini, K. K., Kesarla, V., Manangi, M., Hareesh, P. B., Ranjan, J. K. R., Shetty, A., Chikkanayakanahalli, S. S., Sunil, T., Syamala, S., Tharanath, K., Atal, A., Rajagopal, N., Srinath, B. S., Nk, V., Thirumanikandan, P. L., Mishra, N., Shrivastava, S., Wadhwani, R., Ahmad, R., Haq, Z. A., Behera, P., Dhurwe, R., Haq, R., Jain, V., Karna, S., Pushpalatha, K., Raj, S., Santoshi, J. A., Singh, P., Verma, V., Waindeskar, V., Yadav, M. S., Aziz, Z., Chakraborty, K., Chappity, P., Das, G., Datta, D., Jena, S. K., Kar, M., Khuntia, S., Kumar, P., Kumar, R., Kv, A., Mishra, A., Mishra, S., Mittal, Y., Muduly, D., Panda, R., Panigrahi, S., Parija, S., Patra, S., Rout, B., Sahu, R., Sarkar, S., Singh, S., Sudha, S., Sultania, M., Tripathy, S., Varghese, P., Kansay, R., Kaushik, R., Gupta, S. K., Khare, S., Kumar, V., Mohindra, S., Patil, N., Salunke, P., Savlania, A., Singh, K., Pradeep Krishna, R. V., Narasimhan, G., Rela, M., Appukuttan, A., Goudar, S., Mallick, S., Titus, C., Chidambarasamy, E. S., Madhavan, D., Murugesan, A., Narayanasamy, K., Barani Kumar, P. B., Rajan, F., Vijayaragavan, P., Borthakur, B., Chauhan, T. S., Govil, A., Hanjoora, V. M., Srivastava, A., Tiwari, S., Vishwani, V., Pendyala, K. S., Prasad, N., Bothra, J., Deb, M., Herle, K., Jayaram, H., Kannaiyan, L., Krithiga, A., Mukta, W., Nagpal, P., Pathak, P., Banerjee, S., Chaudhary, R., Choudhary, G. R., Chugh, A., Dixit, P., Elhence, A., Gahlot, N., Garg, M., Ghuman, N. K., Jha, D., Kala, P., Kaur, A., Madduri, V., Pandey, H., Pareek, P., Pathak, M., Rathod, K. J., Rodha, M. S., Saxena, R., Sharma, N., Shekhar, S., Singh, M., Suryanarayanan, B., Vishnoi, J. R., Amin, S., Sharma, T., Murugesan, K., Ramasamy, A. B. S., Chatterjee, D., Gerber, C. G., Naskar, U., Aggarwal, G., Agrawal, S. K., Jain, P., Jain, D., Kewlani, V., Pipara, A., Priya, N., Raja, R., Shakya, S., Thambudorai, R., Kharkongor, D., Akhtar, N., Anand, A., Asnani, M., Chaturvedi, A., Chaurasia, A., Enny, L. E., Garg, S., Jaiswal, A. K., Jaiswal, S., Jaware, Y., Kala, N., Karnatak, R., Kumar, U., Shrivastava, A. K., Mehrotra, S., Mishra, B., Namrata, Ojha, B. K., Ozair, A., Pal, U. S., Pandey, A., Raja, N., Ramakant, P., Roy, A., Sachan, R., Sankhwar, S., Sankhwar, P., Sarin, D., Shukla, A., Singh, K. R., Singh, R., Singh, U., Solanki, V., Sonkar, A. A., Srivastava, C., Suryawanshi, P., Tewarson, V., Verma, R., Verma, M. L., Yadav, A., Chand, G., Chanthar, K. M. M. V., Hoysal, D., Batra, N., Bhatti, A., Chopra, R., David, S., Dhar, T., Dutt, U. K., Dutta, R., Gandhi, S., Haque, P. D., Paul Sudhakar John, B., Veetil, S. K., Kaur, G., Kumar, N., Luther, A., Mahajan, A., Mandrelle, K., Mathews, S., Michael, V., Mukherjee, P., Pargal, P., Paul, R., Phillip, A., Phillips, R., Samuel, A., Singh, N., Singh, I., Singh, A., Grewal, S. S., Singhania, A., Thirumalai, S., Varghese, A., Wesley, J., Thomas, J., Zechariah, P., Ifthikar, M. A., Mathew, R. T., Shetty, R., Vijaykumar, M. V., Hameed, B. M. Z., Ibrahim, S., Jyothish, G., Krishna, S., Mathew, S., Kumar, A. S., Sinha, P. K., Sridhar, R., Agarwal, S., Balasubramaniam, S., Chhatrapati, S., Deshpande, C., Dharia, A., Fernandes, S., Gore, M., Jayakumar, A., Mhamane, R., Nirgude, A., Parab, S., Patil, M., Peswani, A., Sahu, A., Samel, S., Shah, F., Haridas, D., Shetty, V., Abraham, B., Agarwal, V., Ahmad, Q., Asari, A., Attar, M. I., Ayyalasomayajula, N. S., Bachawat, S., Bachhav, S., Badhe, V., Badhwar, S., Basa, V. I. K. A. S., Bothara, V., Chattopadhyay, S., Chaudhari, S., Chavan, R., Chawathe, P., Dadhich, S., Dalal, A., Date, A., Deshpande, M., Dev, P., Dongre, N., Doshi, A., Gade, M., Gajjar, S., Gawande, M., Ghalme, A., Ghugare, B., Gupta, I., Jain, M., Jenasamant, S. S., Joshi, V., Kalwadia, N., Kapadia, N., Kattana, H. B. R., Kaushik, T., Kayal, A., Kovale, S., Kulkarni, Y., Kumar, K., Kumawat, K., Lad, V., Maskara, N., Mistry, R., Mohanty, S. R., Motwani, K., Mulchandani, M., Nadkarni, M., Pandey, S., Parab, M., Pardiwala, D., Patkar, A., Pawar, N., Pawar, A., Pednekar, A., Peshattiwar, V., Pokharkar, H., Potdar, O., Pothare, A., Rahmani, F., Rajput, S., Narendra, N. R., Rao, A., Rao, S., Rohela, H., Sakhrekar, R., Salunkhe, D., Sandlas, G., Sarkar, H., Satpathy, A., Sekhar, R., Shelke, Y., Shetty, S. S., Shetye, S., Kulkarni, A. S., Singal, U., Solanki, F., Sonawane, R., Thete, R., Vhatkar, R., Vora, S., Waigankar, S., Wasnik, S., Yadav, M., Yedave, R., Acharya, H., Bangar, A., Bharucha, M., Dhumane, P., Karmarkar, S., Nathani, R., Nehe, A., Nene, A., Noronha, W. J., Palapalle, N., Patel, P., Poyyil, D., Redkar, R., Shah, M., Tewari, S., Bakshi, G., Chaudhari, V., Deshmukh, A., Desoouza, A., Nair, D., Nayak, P., Patkar, S., Puri, A., Qureshi, S., Shetty, P., Shylasree, T., Thakkar, P., Thiagarajan, S., Tiwari, V. K., Voppuru, S. R., Soni, A., Soni, G., Alam, J., Bagaria, D., Bajpai, M., Bisoi, A. K., Chauhan, S., Choudhary, N., Chouhan, R. S., Chumber, S., Farooque, K., Gudala, V., Joshi, M., Kabra, A., Kale, S. S., Kumar, S., Mahajan, D., Malhotra, R., Menon, P. R., Misra, B., Mittal, S., Parshad, R., Priyadarshini, P., Sagar, S., Sharma, P. B., Sharma, V., Trikha, V., Tyagi, M., Bansal, K., Varma, K., Bhardwaj, R., Mittal, A., Ponnusamy, S., Singh, G. R., Tuli, I., Bhor, P., Dhar, S., Kale, S., Aggarwal, M., Gupta, H., Deshpande, A., Gadekar, A., Jaysingani, T., Panjwani, T., Patil, R., Vaidya, N., Vishwakarma, S. K., Wayal, U., Dutta, D., Arora, R., Dhingra, M., Garg, P. K., Huda, F., Kandwal, P., Kant, R., Seenivasagam, R. K., Joshua, L. M., Poonia, D. R., Rajput, D., Sadhasivam, S., Singh, V., Chandanwale, K., Philip, M., Thorat, V., Choudhury, Y., Das, D., Das, M., Goala, S., Laskar, F. Y., Laskar, P., Malik, K., Sarkar, A., Singha, S. T., Singha, M. N., Singha, D., Srungavarapu, G., Tapkire, R., Tling, S., Andrabi, S. M. I., Bhat, G. A., Chowdri, N., Kour, R., Parray, F., Shah, Z. A. M. I. R. A. H. M. A. D., Wani, R., Adamala, S., Gowder, R., Hegde, S., Mashitha, M. S., Sreeram, S., Ankadavar, S., Bafna, D., Dhanani, B., Ingle, N., Jadhao, P., Joseph, S., Kapote, S., Karkada, S., Lad, P., Lohia, R., Madje, S., Narasiman, V., Chisthi, M., George, G., Jothi, H., Pareed, D., Mathew, G. D. C., Abel, L., Agrawal, M., Rabindranath, B., Baldia, M., Barla, R. K., Beck, M., Benjamin, S., Bliss, J., Cherian, L., Devarakonda, S., Ete, G., George, A. J. P., Iovino, Claudio, CovidSurg Collaborarive, Frisoni T., Palmerini E., Donati D., Traina F., Solaini L., Pignatti M., Conti A., Internal Medicine, Collaborative, COVIDSurg, Collaborative, GlobalSurg, Apollo - University of Cambridge Repository, COVIDSurg Collaborative, Li, E, Emanuele Cammarata, Sofia Campanella, Daniela Canzonieri, Adriana Cordova, Federico De Michele, Ettore Dinoto, Mara Franza, Leo Licari, Daniele Matta, Domenico Mirabella, Felice Pecoraro, Roberto Pirrello, Pierfrancesco Pugliese, Fernando Rosatti, Giuseppe Salamone, Francesca Toia, Massimiliano Tripoli, Vito Chiantera, Leo Licari, Palmisano, Silvia, de Manzini, Nicolo', Collaborative, Covidsurg, Collaborative, Globalsurg, Faculty of Medicine and Pharmacy, Clinical sciences, Medical Oncology, Basic (bio-) Medical Sciences, Diabetes Pathology & Therapy, Gastroenterology, Fruscio, R, Ornaghi, S, Surgical clinical sciences, COVIDSurg Collaborative (GlobalSurg, Collaborative), Beretta, L, and Aldrighetti, L.
Subjects: Male, pulmonary embolism, Internationality, Settore MED/18 - CHIRURGIA GENERALE, Deep vein, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], infectious diseases, Cardiovascular, SARS‐CoV‐2, surgery, COVID-19, SARS-CoV-2, deep vein thrombosis, venous thromboembolism, Cohort Studies, Postoperative Complications, Anesthesiology, Medicine and Health Sciences, Prospective Studies, 610 Medicine & health, Prospective cohort study, Lung, 11 Medical and Health Sciences, Confounding, Hematology, Middle Aged, Thrombosis, 17 Psychology and Cognitive Sciences, Pulmonary embolism, medicine.anatomical_structure, Cohort, COVID-19/complications, Postoperative Complications/etiology, Original Article, Female, Patient Safety, Life Sciences & Biomedicine, Human, Adult, medicine.medical_specialty, Adolescent, Clinical Sciences, GlobalSurg Collaborative, Venous Thromboembolism/etiology, NO, COVIDSurg Collaborative, Young Adult, Medicine, General & Internal, Age Distribution, Clinical Research, COVID‐19, General & Internal Medicine, medicine, Humans, Sex Distribution, Aged, Science & Technology, business.industry, Prevention, Neurosciences, deep vein thrombosi, Pneumonia, Odds ratio, Original Articles, medicine.disease, Surgery, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Prospective Studie, Good Health and Well Being, Anesthesiology and Pain Medicine, Human medicine, Postoperative Complication, Cohort Studie, business, Venous thromboembolism, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS-CoV-2 diagnosis was defined as peri-operative (7 days before to 30 days after surgery); recent (1-6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre-operative anti-coagulation for baseline comorbidities was not available. Postoperative venous thromboembolism rate was 0.5% (666/123,591) in patients without SARS-CoV-2; 2.2% (50/2317) in patients with peri-operative SARS-CoV-2; 1.6% (15/953) in patients with recent SARS-CoV-2; and 1.0% (11/1148) in patients with previous SARS-CoV-2. After adjustment for confounding factors, patients with peri-operative (adjusted odds ratio 1.5 (95%CI 1.1-2.0)) and recent SARS-CoV-2 (1.9 (95%CI 1.2-3.3)) remained at higher risk of venous thromboembolism, with a borderline finding in previous SARS-CoV-2 (1.7 (95%CI 0.9-3.0)). Overall, venous thromboembolism was independently associated with 30-day mortality (5.4 (95%CI 4.3-6.7)). In patients with SARS-CoV-2, mortality without venous thromboembolism was 7.4% (319/4342) and with venous thromboembolism was 40.8% (31/76). Patients undergoing surgery with peri-operative or recent SARS-CoV-2 appear to be at increased risk of postoperative venous thromboembolism compared with patients with no history of SARS-CoV-2 infection. Optimal venous thromboembolism prophylaxis and treatment are unknown in this cohort of patients, and these data should be interpreted accordingly. ispartof: ANAESTHESIA vol:77 issue:1 pages:28-39 ispartof: location:England status: published
Published: 2022

35. ODYSSEY clinical trial design: a randomised global study to evaluate the efficacy and safety of dolutegravir-based antiretroviral therapy in HIV-positive children, with nested pharmacokinetic sub-studies to evaluate pragmatic WHO-weight-band based dolutegravir dosing

Author: Clare Shakeshaft, Carlo Giaquinto, Tim R. Cressey, Adeodata Kekitiinwa, David M. Burger, Pauline Amuge, Pablo Rojo, Cecilia L. Moore, Osee Behuhuma, Yacine Saϊdi, Linda Barlow-Mosha, James Hakim, Alexandra Compagnucci, Lorna Atwine, Diana M. Gibb, Ebrahim Variava, Hilda Mujuru, Mark F. Cotton, Victor Musiime, Moherndran Archary, Deborah Ford, Cissy Kityo, Thanyawee Puthanakit, Anna Turkova, Avy Violari, Abbas Lugemwa, Medical Research Council Clinical Trials Unit (MRC CTU), University College of London [London] (UCL), University of Zimbabwe (UZ), Baylor College of Medicine Children's Foundation [Kampala, Uganda] (BCMCF), Joint Clinical Research Centre, MUJHU Research Collaboration [Kampala, Uganda] (MUJHURC), Chiang Mai University (CMU), Harvard T.H. Chan School of Public Health, University of Liverpool, Perinatal HIV Research Unit [Johannesburg, South Africa] (PHRU), University of the Witwatersrand [Johannesburg] (WITS), Klerksdorp Tshepong Hospital Complex [Matlosana, South Africa] (KTHC), Family Center for Research with Ubuntu [Cape Town, South Africa] (FCRU), Durban International Clinical Research Site [Durban, South Africa] (DICRS), Essais Thérapeutiques et Maladies Infectieuses, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Chulalongkorn University [Bangkok], Africa Health Research Institute [Hlabisa, South Africa] (AHRI), Hlabisa Hospital [Hlabisa, South Africa] (HH), Radboud University Medical Center [Nijmegen], Università degli Studi di Padova = University of Padua (Unipd), Hospital Universitario 12 de Octubre [Madrid], ODYSSEY Trial Team: Shabinah Ali, Abdel Babiker, Chiara Borg, Anne-Marie Borges Da Silva, Joanna Calvert, Deborah Ford, Joshua Gasa, Diana M Gibb, Nasir Jamil, Sarah Lensen, Emma Little, Fatima Mohamed, Samuel Montero, Cecilia L Moore, Rachel Oguntimehin, Anna Parker, Reena Patel, Tasmin Phillips, Tatiana Sarfati, Karen Scott, Clare Shakeshaft, Moira Spyer, Margaret Thomason, Anna Turkova, Rebecca Turner, Nadine Van Looy, Ellen White, Kaya Widuch, Helen Wilkes, Ben Wynne, Carlo Giaquinto, Tiziana Grossele, Daniel Gomez-Pena, Davide Bilardi, Giulio Vecchia, Alexandra Compagnucci, Yacine Saidi, Yoann Riault, Alexandra Coelho, Laura Picault, Christelle Kouakam, Tim R Cressey, Suwalai Chalermpantmetagul, Dujrudee Chinwong, Gonzague Jourdain, Rukchanok Peongjakta, Pra-Ornsuda Sukrakanchana, Wasna Sirirungsi, Janet Seeley, Sarah Bernays, Magda Conway, Nigel Klein, Eleni Nastouli, Anita De Rossi, Maria Angeles Munoz Fernandez, David Burger, Pauline Bollen, Angela Colbers, Hylke Waalewijn, Cissy M Kityo, Victor Musiime, Elizabeth Kaudha, Annet Nanduudu, Emmanuel Mujyambere, Paul Ocitti Labeja, Charity Nankunda, Juliet Ategeka, Peter Erim, Collin Makanga, Esther Nambi, Abbas Lugemwa, Lorna Atwine, Edridah Keminyeto, Deogratiuos Tukwasibwe, Shafic Makumbi, Emily Ninsiima, Mercy Tukamushaba, Rogers Ankunda, Ian Natuhurira, Miriam Kasozi, Baker Rubinga, Adeodata R Kekitiinwa, Pauline Amuge, Dickson Bbuye, Justine Nalubwama, Winnie Akobye, Muzamil Nsibuka Kisekka, Anthony Kirabira, Gloria Ninsiima, Sylvia Namanda, Gerald Agaba, Immaculate Nagawa, Annet Nalugo, Florence Namuli, Rose Kadhuba, Rachael Namuddu, Lameck Kiyimba, Angella Baita, Eunice Atim, Olivia Kobusingye, Clementine Namajja, Africanus Byaruhanga, Rogers Besigye, Herbert Murungi, Geoffrey Onen, Philippa Musoke, Linda Barlow-Mosha, Grace Ahimbisibwe, Rose Namwanje, Monica Etima, Mark Ssenyonga, Robert Serunjogi, Hajira Kataike, Richard Isabirye, David Balamusani, Monica Nolan, Mark F Cotton, Anita Janese van Rensburg, Marlize Smuts, Catherine Andrea, Sumaya Dadan Sonja Pieterse, Vinesh Jaeven, Candice Makola, George Fourie, Kurt Smith, Els Dobbels, Peter Zuidewind, Hesti Van Huyssteen, Mornay Isaacs, Georgina Nentsa, Thabis Ncgaba, Candice MacDonald, Mandisa Mtshagi, Maria Bester, Wilma Orange, Ronelle Arendze, Mark Mulder, George Fourie, Avy Violari, Nastassja Ramsagar, Afaaf Liberty, Ruth Mathiba, Lindiwe Maseko, Nakata Kekane, Busi Khumlo, Mirriam Khunene, Noshalaza Sbisi, Jackie Brown, Ryphina Madonsela, Nokuthula Mbadaliga, Zaakirah Essack, Reshma Lakha, Aasia Vadee, Derusha Frank, Nazim Akoojee, Maletsatsi Monametsi, Gladness Machache, Yolandie Fourie, Anusha Nanan-Kanjee, Juan Erasmus, Angelous Mamiane, Tseleng Daniel, Fatima Mayat, Nomfundo Maduna, Patsy Baliram, Chaiwat Ngampiyasakul, Pisut Greetanukroh, Wanna Chamjamrat, Praechadaporn Khannak, Pornchai Techakunakorn, Thitiwat Thapwai, Patcharee Puangmalai, Ampai Maneekaew, Pradthana Ounchanum, Yupawan Thaweesombat, Areerat Kongponoi, Jutarat Thewsoongnoen, Suparat Kanjanavanit, Pacharaporn Yingyong, Thida Namwong, Rangwit Junkaew, Ussanee Srirompotong, Patamawadee Sudsaard, Siripun Nuanbuddee, Sookpanee Wimonklang, Sathaporn Na-Rajsima, Suchart Thongpaen, Pattira Runarassamee, Watchara Meethaisong, Arttasid Udomvised, Ebrahim Variava, Modiehi Rakgokong, Dihedile Scheppers, Tumelo Moloantoa, Abdul Hamid Kaka, Tshepiso Masienyane, Akshmi Ori, Kgosimang Mmolawa, Pattamukkil Abraham, Moherndran Archary, Rejoice Mosia, Sajeeda Mawlana, Rosie Mngqibisa, Rashina Nundlal, Elishka Singh, Penelope Madlala, Allemah Naidoo, Sphiwee Cebekhulu, Petronelle Casey, Collin Pillay, Subashinie Sidhoo, Minenhle Chikowore, Lungile Nyantsa, Melisha Nunkoo, Terence Nair, Enbavani Pillay, Sheleika Singh, Sheroma Rajkumar, Osee Behuhuma, Olivier Koole, Kristien Bird, Nomzamo Buthelezi, Mumsy Mthethwa, James Hakim, Hilda Mujuru, Kusum Nathoo, Mutsa Bwakura-Dangarembizi, Ennie Chidziva, Shepherd Mudzingwa, Themelihle Bafana, Colin Warambwa, Godfrey Musoro, Gloria Tinago, Shirley Mutsai, Columbus Moyo, Ruth Nhema, Misheck Nkalo Phiri, Stuart Chitongo, Joshua Choga, Joyline Bhiri, Wilber Ishemunyoro, Makhosonke Ndlovu, Thanyawee Puthanakit, Naruporn Kasipong, Sararut Chanthaburanun, Kesdao Nanthapisal, Thidarat Jupimai, Thornthun Noppakaorattanamanee, Torsak Bunupuradah, Wipaporn Natalie Songtaweesin, Chutima Saisaengjan, Stephan Schultze-Straber, Christoph Konigs, Robin Kobbe, Felicia Mantkowski, Steve Welch, Jacqui Daglish, Laura Thrasyvoulou, Delane Singadia, Sophie Foxall, Judith Acero, Gosia Pasko-Szcech, Jacquie Flynn, Gareth Tudor-Williams, Farhana Abdulla, Srini Bandi, Jin Li, Sean O'Riordan, Dominique Barker, Richard Vowden, Colin Ball Eniola Nsirim, Kathleen McClughlin, India Garcia, Pablo Rojo Conejo, Cristina Epalza, Luis Prieto Tato, Maite Fernandez, Luis Escosa Garcia, Maria José Mellado Peña, Talia Sainz Costa, Claudia Fortuny Guasch, Antoni Noguera Julian, Carolina Estepa, Elena Bruno, Alba Murciano Cabeza, Maria Angeles Muñoz Fernandez, Paula Palau, Laura Marques, Carla Teixeira, Alexandre Fernandes, Rosita Nunes, Helena Nascimento, Andreia Padrao, Joana Tuna, Helena Ramos, Ana Constança Mendes, Helena Pinheiro, Ana Cristina Matos, Flavia Kyomuhendo, Sarah Nakalanzi, Cynthia Mukisa Williams, Ntombenhle Ngcobo, Deborah Pako, Jacky Crisp, Benedictor Dube, Precious Chandiwana, Winnie Gozhora, Ian Weller, Elaine Abrams, Tsitsi Apollo, Polly Clayden, Valériane Leroy, Anton Pozniak, Jane Crawley, Rodolphe Thiébaut, Helen McIlleron, Alasdair Bamford, Hermione Lyall, Andrew Prendergast, Felicity Fitzgerald, Anna Goodman, Malbec, Odile, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11), Radboud University Medical Centre [Nijmegen, The Netherlands], and Universita degli Studi di Padova
Subjects: 0301 basic medicine, Male, Pediatrics, [SDV]Life Sciences [q-bio], HIV Infections, Basket trial, Dolutegravir, Efficacy, HIV, Paediatric, Pharmacokinetic, Randomized control trial, Safety, Adolescent, Body Weight, Child, Child, Preschool, Cohort Studies, Drug Dosage Calculations, Europe, Female, HIV Integrase Inhibitors, HIV-1, Heterocyclic Compounds, 3-Ring, Humans, Oxazines, Piperazines, Pyridones, RNA, Viral, South Africa, Thailand, Treatment Outcome, Uganda, Viral Load, World Health Organization, Zimbabwe, law.invention, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, Heterocyclic Compounds, law, Clinical endpoint, Medicine, Viral, 030212 general & internal medicine, 3. Good health, [SDV] Life Sciences [q-bio], Infectious Diseases, Viral load, Cohort study, Research Article, medicine.medical_specialty, 030106 microbiology, 3-Ring, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, lcsh:RC109-216, Dosing, Preschool, Pregnancy, business.industry, Clinical study design, medicine.disease, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], chemistry, RNA, business
Abstract: Background Dolutegravir (DTG)-based antiretroviral therapy (ART) is highly effective and well-tolerated in adults and is rapidly being adopted globally. We describe the design of the ODYSSEY trial which evaluates the efficacy and safety of DTG-based ART compared with standard-of-care in children and adolescents. The ODYSSEY trial includes nested pharmacokinetic (PK) sub-studies which evaluated pragmatic World Health Organization (WHO) weight-band-based DTG dosing and opened recruitment to children Methods ODYSSEY (Once-daily DTG based ART in Young people vS. Standard thErapY) is an open-label, randomised, non-inferiority, basket trial comparing the efficacy and safety of DTG + 2 nucleos(t) ides (NRTIs) versus standard-of-care (SOC) in HIV-infected children Results Between September 2016 and June 2018, 707 children weighing ≥14 kg were enrolled; including 311 ART-naïve children and 396 children starting second-line. 47% of children were enrolled in Uganda, 21% Zimbabwe, 20% South Africa, 9% Thailand, 4% Europe. 362 (51%) participants were male; median age [range] at enrolment was 12.2 years [2.9–18.0]. 82 (12%) children weighed 14 to Conclusions By employing a basket design, to include ART-naïve and -experienced children, and nested PK sub-studies, the ODYSSEY trial efficiently evaluates multiple scientific questions regarding dosing and effectiveness of DTG-based ART in children. Trial registration NCT, NCT02259127, registered 7th October 2014; EUDRACT, 2014–002632-14, registered 18th June 2014 (https://www.clinicaltrialsregister.eu/ctr-search/trial/2014-002632-14/ES); ISRCTN, ISRCTN91737921, registered 4th October 2014.
Published: 2021

36. A roadmap to better COVID-19 testing from the Coronavirus Standards Working Group

Author: Patrick S. G. Chain, Deepa Eveleigh, Michael A. Crone, no mistake, Jo Vandesompele, Neil Almond, Mojca Milavec, Martin Kammel, Sebastien Fuchs, John J. Sninsky, Tim R. Mercer, Birgitte Simen, Russell Garlick, Peter M. Vallone, Gary Pestano, Cristina Tato, Heinz Zeichhardt, Mark Page, Lynne Sopchak, Thomas J. White, Po-E Li, Elizabeth Marlowe, Alina Deshpande, Marc L. Salit, Sara Suliman, Paul S. Freemont, Denise M. O'Sullivan, and Jim F. Huggett
Subjects: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, Group (periodic table), Family medicine, Medicine, business, medicine.disease_cause, Coronavirus
Abstract: Testing has been central to our response to the COVID-19 pandemic. However, the accuracy of testing relies on standards, including reference materials, proficiency testing schemes, and information and reporting guidelines. The use of standards is a simple, inexpensive, and effective method to ensure reliable test results that inform clinical and public health decisions. Here we describe the central role of standards during the COVID-19 pandemic, where they have enabled population-scale screening, genomic surveillance and measures of immune protection measures. Given these benefits, the Coronavirus Standards Working Group (CSWG) was formed to coordinate standards in SARS-CoV-2 testing. This network of scientists has developed best-practices, reference materials, and conducted proficiency studies to harmonize laboratory performance. We propose that this coordinated development of standards should be prioritized as a key early step in the public health response to future pandemics that is necessary for reliable, large-scale testing for infectious disease.
Published: 2021

37. Emerging technologies and their impact on regulatory science

Author: Reinhilde Schoonjans, Janny van den Eijnden-van-Raaij, Munir Pirmohamed, Susan Sumner, Stefan Platz, Seichi Ishida, Alexandre Js Ribeiro, Danilo A. Tagle, Suzanne Fitzpatrick, Hajime Kojima, Primal Silva, Uwe Marx, Li Tong, Richard D. Beger, Masamitsu Honma, Philippe Girard, Tim R. Mercer, Robert Ball, David S. Wishart, George E.N. Kass, Kyung E. Sung, Ira Krefting, Carmen Pelaez, Elke Anklam, Hairuo Wen, Weida Tong, Martin Iain Bahl, Blanka Halamoda-Kenzaoui, Reza M. Salek, Arnd Hoeveler, Yinyin Yuan, Yan Liu, Joseph V Rodricks, Neil Vary, William Slikker, John C. Waterton, Tao Wang, Shane Masters, May D. Wang, Akihiko Hirose, Timothy J. McCarthy, Ivan Rusyn, Serguei Liachenko, Denise Hinton, Marta Hugas, Clive N. Svendsen, Anil K. Patri, and Jonathan Cohen
Subjects: Personal care, Knowledge management, Biomedical Research, Emerging technologies, business.industry, In silico, Humans, Regulatory science, Computer Simulation, Business, Minireview, Risk assessment, General Biochemistry, Genetics and Molecular Biology
Abstract: et al., There is an evolution and increasing need for the utilization of emerging cellular, molecular and in silico technologies and novel approaches for safety assessment of food, drugs, and personal care products. Convergence of these emerging technologies is also enabling rapid advances and approaches that may impact regulatory decisions and approvals. Although the development of emerging technologies may allow rapid advances in regulatory decision making, there is concern that these new technologies have not been thoroughly evaluated to determine if they are ready for regulatory application, singularly or in combinations. The magnitude of these combined technical advances may outpace the ability to assess fit for purpose and to allow routine application of these new methods for regulatory purposes. There is a need to develop strategies to evaluate the new technologies to determine which ones are ready for regulatory use. The opportunity to apply these potentially faster, more accurate, and cost-effective approaches remains an important goal to facilitate their incorporation into regulatory use. However, without a clear strategy to evaluate emerging technologies rapidly and appropriately, the value of these efforts may go unrecognized or may take longer. It is important for the regulatory science field to keep up with the research in these technically advanced areas and to understand the science behind these new approaches. The regulatory field must understand the critical quality attributes of these novel approaches and learn from each other's experience so that workforces can be trained to prepare for emerging global regulatory challenges. Moreover, it is essential that the regulatory community must work with the technology developers to harness collective capabilities towards developing a strategy for evaluation of these new and novel assessment tools.
Published: 2021

38. First Line and Second Line Chemotherapy in Advanced Cholangiocarcinoma and Impact of Dose Reduction of Chemotherapy: A Retrospective Analysis

Author: Martin W. von Websky, Peter Brossart, Jörg C. Kalff, Farsaneh Sadeghlar, Raphael Mohr, Christian Möhring, Hanno Matthaei, Tim R. Glowka, Christian P. Strassburg, Maria A. Gonzalez-Carmona, Jan Feder, Milka Marinova, Robert Mahn, Georg Feldmann, Steffen Manekeller, Alexandra Bartels, Tobias J. Weismüller, and Taotao Zhou
Subjects: Oncology, Cancer Research, medicine.medical_specialty, First line, medicine.medical_treatment, cholangiocellular carcinoma, FOLFIRI, Internal medicine, Retrospective analysis, Medicine, gemcitabine/cisplatin, Adverse effect, RC254-282, second line palliative chemotherapy, Original Research, Chemotherapy, first line palliative chemotherapy, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, retrospective analysis, Gemcitabine, Regimen, Cohort, bile duct carcinoma, business, medicine.drug
Abstract: ObjectivePrognosis of patients with irresectable cholangiocarcinoma is still poor. The ABC-02 trial established the current first line (1L) standard systemic chemotherapy (CT) with gemcitabine/platinum derivate for advanced cholangiocarcinoma. However, the majority of patients needed therapy adaptions. Thus, the aim of this study was to evaluate 1L and second line (2L) therapy regimens and the impact of therapy adaptions in an unselected real-life cohort of patients with advanced cholangiocarcinoma.Materials and MethodsThis is a single institution retrospective analysis of patients with irresectable cholangiocarcinoma who were treated with gemcitabine/platinum derivate from 2010 to 2018. Overall survival (OS), progression-free survival (PFS) and toxicity were analyzed for all patients, especially with regard to CT de-escalation.ResultsFifty-eight patients receiving gemcitabine/platinum derivate were included in the analysis. Median OS and PFS were 12.2 and 6.9 months. Interestingly, 41 patients (71%) needed therapy de-escalation. However, despite reduced CT exposition, there was no-significant difference in OS (10.8 months vs. 15.6 months, p = 0.127), and patients suffered from less adverse events during CT. 21 (36%) patients reached 2L CT, most often with FOLFIRI (57%). Survival beyond the end of 1L CT was 7.1 months with 2L CT vs. 2.9 months with BSC.ConclusionIn our study, the combination of gemcitabine/platinum derivate showed similar OS and PFS as randomized prospective phase II/III trials. Therapy regimen adaptions were needed in the majority of patients. However, individualized modifications of the therapy regimen allowed better tolerance as well as continuation of therapy and did not significantly influence median OS. Furthermore, our study revealed a potential survival benefit with 2L CT for selected patients.
Published: 2021

39. Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy

Author: Tim R Eijgenraam, Cornelis J. Boogerd, Xiaoke Yin, Manuel Mayr, Lukas E Schmidt, Herman H W Silljé, Eva van Rooij, Peter van der Meer, Nienke M Stege, Martin M Dokter, Rudolf A. de Boer, Vivian Oliveira Nunes Teixeira, Jolanda van der Velden, Konstantinos Theofilatos, Cardiovascular Centre (CVC), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Hubrecht Institute for Developmental Biology and Stem Cell Research, Physiology, and ACS - Heart failure & arrhythmias
Subjects: Cardiomyopathy, Dilated, cardiomyopathies, endocrine system, Heart Failure/metabolism, Mutation/genetics, Cardiomyopathy, Dilated/genetics, Cardiomyopathy, Myocardium/metabolism, Cardiomyopathies/genetics, heart failure, Mice, Transgenic, Protein aggregation, Proteomics, medicine.disease_cause, Bioinformatics, Transgenic, Protein Aggregates, Mice, proteomics, medicine, Protein Aggregates/physiology, Gene, Mutation, business.industry, Myocardium, Calcium-Binding Proteins, Original Articles, medicine.disease, Pathophysiology, Phospholamban, animals, Phenotype, Dilated/genetics, Heart failure, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, mutation, Cardiology and Cardiovascular Medicine, business
Abstract: Supplemental Digital Content is available in the text., Background: The p.(Arg14del) pathogenic variant (R14del) of the PLN (phospholamban) gene is a prevalent cause of cardiomyopathy with heart failure. The exact underlying pathophysiology is unknown, and a suitable therapy is unavailable. We aim to identify molecular perturbations underlying this cardiomyopathy in a clinically relevant PLN-R14del mouse model. Methods: We investigated the progression of cardiomyopathy in PLN-R14Δ/Δ mice using echocardiography, ECG, and histological tissue analysis. RNA sequencing and mass spectrometry were performed on cardiac tissues at 3 (before the onset of disease), 5 (mild cardiomyopathy), and 8 (end stage) weeks of age. Data were compared with cardiac expression levels of mice that underwent myocardial ischemia-reperfusion or myocardial infarction surgery, in an effort to identify alterations that are specific to PLN-R14del–related cardiomyopathy. Results: At 3 weeks of age, PLN-R14Δ/Δ mice had normal cardiac function, but from the age of 4 weeks, we observed increased myocardial fibrosis and impaired global longitudinal strain. From 5 weeks onward, ventricular dilatation, decreased contractility, and diminished ECG voltages were observed. PLN protein aggregation was present before onset of functional deficits. Transcriptomics and proteomics revealed differential regulation of processes involved in remodeling, inflammation, and metabolic dysfunction, in part, similar to ischemic heart disease. Altered protein homeostasis pathways were identified exclusively in PLN-R14Δ/Δ mice, even before disease onset, in concert with aggregate formation. Conclusions: We mapped the development of PLN-R14del–related cardiomyopathy and identified alterations in proteostasis and PLN protein aggregation among the first manifestations of this disease, which could possibly be a novel target for therapy.
Published: 2021

40. Simplifying TREAtment and Monitoring for HIV (STREAM HIV): protocol for a randomised controlled trial of point-of-care urine tenofovir and viral load testing to improve HIV outcomes

Author: Kogieleum Naidoo, Salim S. Abdool Karim, Monica Gandhi, Tim R. Cressey, Hope Ngobese, Katherine K. Thomas, Jienchi Dorward, Justice Quame-Amaglo, Paul K. Drain, Fathima Sayed, Erika Feutz, Nigel Garrett, Jane M. Simoni, Pravi Moodley, Connie Celum, Richard J Lessells, Yukteshwar Sookrajh, Nivashnee Naicker, Monisha Sharma, Cheryl. Pillay, and Ashley Bardon
Subjects: medicine.medical_specialty, Anti-HIV Agents, Point-of-Care Systems, HIV & AIDS, HIV Infections, law.invention, South Africa, Randomized controlled trial, Acquired immunodeficiency syndrome (AIDS), law, Epidemiology, Medicine, Humans, Tenofovir, Randomized Controlled Trials as Topic, clinical trials, international health services, business.industry, public health, General Medicine, Viral Load, Institutional review board, medicine.disease, Clinical trial, Regimen, Anti-Retroviral Agents, Point-of-Care Testing, Emergency medicine, HIV/AIDS, epidemiology, business, Viral load, HIV drug resistance
Abstract: IntroductionSubstantial improvements in viral suppression among people living with HIV (PLHIV) are needed to end the HIV epidemic, requiring extensive scale-up of low-cost HIV monitoring services. Point-of-care (POC) tests for monitoring antiretroviral therapy (ART) adherence and viral load (VL) may be efficient and effective tools for real-time clinical decision making. We aim to evaluate the effects of a combined intervention of POC ART adherence and VL testing compared with standard-of-care on ART adherence, viral suppression and retention at 6 and 18 months post-ART initiation among PLHIV.Methods and analysisSimplifying TREAtment and Monitoring for HIV (STREAM HIV) is a two-arm, open-label, randomised controlled superiority trial of POC urine tenofovir (POC TFV) and VL monitoring in PLHIV. We aim to enrol 540 PLHIV initiating a first-line ART regimen at a public HIV clinic in South Africa. Participants will be randomised 1:1 to the intervention or control arm. Intervention arm participants will receive monthly POC TFV testing for the first 5 months and POC VL testing at months 6 and 12. Intervention arm participants will also receive reflex POC TFV testing if viraemic and reflex HIV drug resistance testing for those with viraemia and detectable TFV. Control arm participants will receive standard-of-care, including laboratory-based VL testing at months 6 and 12. Primary outcomes include ART adherence (TFV-diphosphate concentration) at 6 months and viral suppression and retention at 18 months. Secondary outcomes include viral suppression and retention at 6 months, TFV-diphosphate concentration at 18 months, cost and cost-effectiveness of the intervention and acceptability of the intervention among PLHIV and healthcare workers.Ethics and disseminationSTREAM HIV has received ethical approval from the University of Washington Institutional Review Board (STUDY00007544), University of KwaZulu-Natal Biomedical Research Ethics Committee (BREC/00000833/2019) and Division of AIDS Regulatory Support Center (38509). Findings will be disseminated at international conferences and in peer-reviewed journals.Trial registration numberNCT04341779.
Published: 2021

41. Point-of-care semiquantitative test for adherence to tenofovir alafenamide or tenofovir disoproxil fumarate

Author: Derin Sevenler, Mehmet Toner, Paul K. Drain, Tim R. Cressey, Rebecca D. Sandlin, Xin Niu, and Sandy Dossantos
Subjects: medicine.medical_specialty, Tenofovir, medicine.diagnostic_test, business.industry, Objective measurement, Urine, Tenofovir alafenamide, Gastroenterology, Highly sensitive, Pharmacokinetics, Internal medicine, Immunoassay, medicine, business, medicine.drug, Point of care
Abstract: SynopsisObjectiveObjective measurement of antiretrovirals may aid clinical interventions for improving adherence to HIV prevention or treatment regimens. A point-of-care urine test could provide real-time information about recent adherence to regimens containing tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide (TAF). We developed a lateral flow immunoassay (LFA) and enzyme-linked immunoassay (ELISA) for urinary tenofovir.MethodsIntensity of the LFA test line was quantified using an optical reader and visually scored 0 – 5 by two independent people, using a reference card. The sensitivity and specificity of both the ELISA and LFA were determined for two different tenofovir concentration cutoffs for TDF and TAF adherence—1,500 ng/mL and 150 ng/mL, respectively. To validate the assays, we measured 586 urine samples from 28 individuals collected as part of a study of tenofovir pharmacokinetics in adults, which were also measured by mass spectrometry as ground truth.ResultsBoth the LFA signal and ELISA signal were each strongly correlated to drug concentrations (0.91 and 0.92 respectively). The LFA signal and ELISA were highly sensitive and specific at both thresholds (LFA se/sp TDF 89%/96%, TAF 90%/96%; ELISA se/sp TDF 94%/94%, TAF 92%/84%). Visual scoring of the LFA was also highly sensitive and specific at both the TDF and TAF thresholds (se/sp TDF 91%/94%, TAF 87%/90%).ConclusionsOur rapid semi-quantitative test can measure TFV concentrations relevant to both TAF or TDF adherence, which may support adherence-promoting interventions across a range of HIV care settings.
Published: 2021

42. A Simulation Study of the Use of Vaccination to Control Foot-and-Mouth Disease Outbreaks Across Australia

Author: Tim R. Capon, Michael G. Garner, Sorada Tapsuwan, Sharon Roche, Andrew C. Breed, Shuang Liu, Corissa Miller, Richard Bradhurst, and Sam Hamilton
Subjects: medicine.medical_specialty, Veterinary medicine, AADIS, Population, Disease, Environmental health, SF600-1100, Epidemiology, medicine, Duration (project management), education, Original Research, education.field_of_study, General Veterinary, Foot-and-mouth disease, outbreak, business.industry, Outbreak, medicine.disease, vaccination, stamping out, Vaccination, livestock, Livestock, Veterinary Science, Australian animal disease spread model, epidemiology, business
Abstract: This study examines the potential for foot-and-mouth disease (FMD) control strategies that incorporate vaccination to manage FMD spread for a range of incursion scenarios across Australia. Stakeholder consultation was used to formulate control strategies and incursion scenarios to ensure relevance to the diverse range of Australian livestock production regions and management systems. The Australian Animal Disease Spread model (AADIS) was used to compare nine control strategies for 13 incursion scenarios, including seven control strategies incorporating vaccination. The control strategies with vaccination differed in terms of their approaches for targeting areas and species. These strategies are compared with two benchmark strategies based on stamping out only. Outbreak size and duration were compared in terms of the total number of infected premises, the duration of the control stage of an FMD outbreak, and the number of vaccinated animals. The three key findings from this analysis are as follows: (1) smaller outbreaks can be effectively managed by stamping out without vaccination, (2) the size and duration of larger outbreaks can be significantly reduced when vaccination is used, and (3) different vaccination strategies produced similar reductions in the size and duration of an outbreak, but the number of animals vaccinated varied. Under current international standards for regaining FMD-free status, vaccinated animals need to be removed from the population at the end of the outbreak to minimize trade impacts. We have shown that selective, targeted vaccination strategies could achieve effective FMD control while significantly reducing the number of animals vaccinated.
Published: 2021

43. One dose does not fit all: revising the WHO paediatric dosing tool to include the non-linear effect of body size and maturation

Author: Tim R. Cressey, Paolo Denti, Roeland E Wasmann, Edmund V. Capparelli, Nandita Sugandhi, Jose Francis, Mark Mirochnick, Helen McIlleron, and Martina Penazzato
Subjects: Adolescent, Dose-Response Relationship, Drug, business.industry, Body Weight, HIV Infections, Body size, Adolescent Development, World Health Organization, Pediatrics, Child Development, Anti-Retroviral Agents, Pediatrics, Perinatology and Child Health, Developmental and Educational Psychology, Medicine, Humans, Dosing, business, Child, Biomedical engineering
Published: 2021

44. Analyzing Assessment Practices for Indigenous Students

Author: Tim R. Claypool and Jane P. Preston
Subjects: 020205 medical informatics, media_common.quotation_subject, indigenous people, Standardized test, 02 engineering and technology, Indigenous, Education, Pedagogy, 0202 electrical engineering, electronic engineering, information engineering, Quality (business), Sociology, L7-991, Disadvantage, media_common, business.industry, student assessment and evaluation, 05 social sciences, Professional development, Theory of multiple intelligences, aboriginal people, 050301 education, Education (General), document analysis, first nation education, business, 0503 education, Meaning (linguistics), Qualitative research
Abstract: The purpose of this article is to review common assessment practices for Indigenous students. We start by presenting positionalities—our personal and professional background identities. Then we explain common terms associated with Indigeneity and Indigenous and Western worldviews. We describe the meaning of document analysis, the chosen qualitative research design, and we explicate the delimitations and limitations of the paper. The review of the literature revealed four main themes. First, assessment is subjugated by a Western worldview. Next, many linguistic assessment practices disadvantage Indigenous students, and language-specific and culture-laden standardized tests are often discriminatory. Last, there is a pervasive focus on cognitive assessment. We discuss how to improve assessment for Indigenous students. For example, school divisions and educators need quality professional development and knowledge about hands-on assessment, multiple intelligences, and Western versus Indigenous assessment inconsistencies. Within the past 20 years, assessment tactics for Indigenous students has remained, more or less, the same. We end with a short discussion addressing this point.
Published: 2021

45. Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone

Author: Dirkje W. Sommeijer, Matthew T. Seymour, Lianne Koens, Cornelis J. A. Punt, Sanne ten Hoorn, David Fisher, Tim Maughan, Louis Vermeulen, Faye Elliott, Anne Trinh, Phil Quirke, Susan D. Richman, Jenny F. Seligmann, Tim R. de Back, Richard Adams, Center of Experimental and Molecular Medicine, Graduate School, CCA - Cancer biology and immunology, Amsterdam Gastroenterology Endocrinology Metabolism, Oncology, and Pathology
Subjects: Male, Proto-Oncogene Proteins B-raf, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Colorectal cancer, medicine.medical_treatment, Cetuximab, Irinotecan, Article, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Text mining, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Chemotherapy, Humans, Panitumumab, Neoplasm Metastasis, Protein Kinase Inhibitors, Aged, Retrospective Studies, Clinical Trials as Topic, business.industry, Middle Aged, medicine.disease, Survival Analysis, Oxaliplatin, ErbB Receptors, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, ras Proteins, Immunohistochemistry, Female, Colorectal Neoplasms, business, medicine.drug
Abstract: Background Patient selection for addition of anti-EGFR therapy to chemotherapy for patients with RAS and BRAF wildtype metastatic colorectal cancer can still be optimised. Here we investigate the effect of anti-EGFR therapy on survival in different consensus molecular subtypes (CMSs) and stratified by primary tumour location. Methods Retrospective analyses, using the immunohistochemistry-based CMS classifier, were performed in the COIN (first-line oxaliplatin backbone with or without cetuximab) and PICCOLO trial (second-line irinotecan with or without panitumumab). Tumour tissue was available for 323 patients (20%) and 349 (41%), respectively. Results When using an irinotecan backbone, anti-EGFR therapy is effective in both CMS2/3 and CMS4 in left-sided primary tumours (progression-free survival (PFS): HR 0.44, 95% CI 0.26–0.75, P = 0.003 and HR 0.12, 95% CI 0.04–0.36, P P = 0.02). Efficacy using an oxaliplatin backbone was restricted to left-sided CMS2/3 tumours (HR 0.57, 95% CI 0.36–0.96, P = 0.034). Conclusions The subtype-specific efficacy of anti-EGFR therapy is dependent on the chemotherapy backbone. This may provide the possibility of subtype-specific treatment strategies for a more optimal use of anti-EGFR therapy.
Published: 2021

46. Q-DEPICT: Qatar Determining Emergency Physician Incidence of COVID-Positive Testing

Author: Zain A. Bhutta, Kodumayil, Ashid, Thomas, Sarah A., Stephen H. Thomas, Sameer A. Pathan, Qureshi, Isma, Azad, Aftab, Harris, Tim R., Shada A. Kodumayil, and Clinicum
Subjects: business.industry, medicine.medical_treatment, Incidence (epidemiology), Testing, COVID-19, Endotracheal intubation, General Medicine, Emergency department, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, Test (assessment), emergency medicine, Prediction model, 3121 General medicine, internal medicine and other clinical medicine, Workforce, Medicine, Airway management, Medical emergency, Emergency physician, business, Personal protective equipment, Qatar, Research Paper
Abstract: Despite protective measures such as personal protective equipment (PPE) and a COVID airway management program (CAMP), some emergency physicians will inevitably test positive for COVID. We aim to develop a model predicting weekly numbers of emergency physician COVID converters to aid operations planning. The data were obtained from the electronic medical record (EMR) used throughout the national healthcare system. Hamad Medical Corporation's internal emergency medicine workforce data were used as a source of information on emergency physician COVID conversion and numbers of emergency physicians completing CAMP training. The study period included the spring and summer months of 2020 and started on March 7 and ran for 21 whole weeks through July 31. Data were extracted from the system's EMR database into a spreadsheet (Excel, Microsoft, Redmond, USA). The statistical software used for all analyses and plots was Stata (version 16.1 MP, StataCorp, College Station, USA). All data definitions were made a priori. A total of 35 of 250 emergency physicians (14.0%, 95% CI 9.9%–19.9%) converted to a positive real-time reverse transcriptase-polymerase chain reaction (PCR) during the study's 21-week period. Of these. only two were hospitalized for having respiratory-only disease, and none required respiratory support. Both were discharged within a week of admission. The weekly number of newly COVID-positive emergency physicians was zero and was seen in eight of 21 (38.1%) weeks. The peak weekly counts of six emergency physicians with new COVID-positive were seen in week 14. The mean weekly number of newly COVID-positive emergency physicians was 1.7 ± 1.9, and the median was 1 (IQR, 0 to 3). This study demonstrates that in the State of Qatar's Emergency Department (ED) system, knowing only four parameters allows the reliable prediction of the number of emergency physicians likely to convert COVID PCR tests within the next week. The results also suggest that attention to the details of minimizing endotracheal intubation (ETI) risk can eliminate the expected finding of the association between ETI numbers and emergency physician COVID numbers. [ABSTRACT FROM AUTHOR] Copyright of Qatar Medical Journal is the property of Hamad bin Khalifa University Press (HBKU Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Published: 2021

47. Fluid overload due to intravenous fluid therapy for vaso-occlusive crisis in sickle cell disease: incidence and risk factors

Author: Man Wai Tang, Koen de Heer, Charlotte F. van Tuijn, Harriët Heijboer, Jorn J. Gerritsma, Tim R. de Back, Ajab K. Sayedi, Erfan Nur, Aafke E. Gaartman, Bart J. Biemond, Graduate School, Clinical Haematology, ACS - Pulmonary hypertension & thrombosis, Center of Experimental and Molecular Medicine, Nursing, and Paediatric Haematology
Subjects: Adult, Male, vaso‐occlusive crisis, Adolescent, Diastole, Disease, Anemia, Sickle Cell, fluid therapy, Young Adult, pulmonary oedema, Intravenous fluid, Interquartile range, Risk Factors, Medicine, Humans, Adverse effect, fluid overload, Retrospective Studies, vaso-occlusive crisis, business.industry, Incidence (epidemiology), Incidence, Hematology, medicine.disease, Haemoglobinopathies, Hospitalization, Anesthesia, Administration, Intravenous, Female, sickle cell disease, business, Complication, Vaso-occlusive crisis, Research Paper
Abstract: Summary Intravenous fluid therapy (IV‐FT) is routinely used in the treatment of vaso‐occlusive crises (VOCs), as dehydration possibly promotes and sustains erythrocyte sickling. Patients with sickle cell disease (SCD) are at risk of developing diastolic dysfunction and fluid overload due to IV‐FT. However, data on the adverse effects of IV‐FT for VOC is sparse. We aimed to evaluate the incidence and risk factors of fluid overload due to IV‐FT in patients with SCD. Consecutive hospitalisations for VOC treated with IV‐FT between September 2016 and September 2018 were retrospectively analysed. The median (interquartile range) age was 25·0 (18·3–33·8) years and 65% had a severe genotype (HbSS/HbSβ0‐thal). Fluid overload occurred in 21% of 100 patients. Hospital stay was longer in patients with fluid overload (6·0 vs. 4·0 days, P = 0·037). A positive history of fluid overload (P = 0·017), lactate dehydrogenase level (P = 0·011), and top‐up transfusion during admission (P = 0·005) were independently associated with fluid overload occurrence. IV‐FT was not reduced in 86% of patients despite a previous history of fluid overload. Fluid overload is frequently encountered during IV‐FT for VOC. IV‐FT is often not adjusted despite a positive history of fluid overload or when top‐up transfusion is indicated, emphasising the need for more awareness of this complication and a personalised approach.
Published: 2021

48. Chronic Liver Disease Increases Mortality Following Pancreatoduodenectomy

Author: Tim O. Vilz, Jana Enderes, Tim R. Glowka, Jessica Teschke, Jörg C. Kalff, and Steffen Manekeller
Subjects: medicine.medical_specialty, Cirrhosis, delayed gastric emptying, medicine.medical_treatment, Chronic liver disease, Gastroenterology, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Internal medicine, medicine, Risk factor, Gastric emptying, business.industry, Mortality rate, cirrhosis, fungi, fibrosis, General Medicine, medicine.disease, Pancreaticoduodenectomy, Whipple, Intensive care unit, Parenteral nutrition, 030220 oncology & carcinogenesis, Medicine, 030211 gastroenterology & hepatology, pancreaticoduodenectomy, business
Abstract: According to the International Study Group of Pancreatic Surgery (ISGPS), data about the impact of pre-existing liver pathologies on delayed gastric emptying (DGE) after pancreatoduodenectomy (PD) according to the definitions of the International Study Group of Pancreatic Surgery (ISGPS) are lacking. We therefore investigated the impact of DGE after PD according to ISGPS in patients with liver cirrhosis (LC) and advanced liver fibrosis (LF). Patients were analyzed with respect to pre-existing liver pathologies (LC and advanced LF, n = 15, 6% vs. no liver pathologies, n = 240, 94%) in relation to demographic factors, comorbidities, intraoperative characteristics, mortality and postoperative complications, with special emphasis on DGE. DGE was equally distributed (DGE grade A, p = 1.000, B, p = 0.396, C, p = 0.607). Particularly, the first day of solid food intake (p = 0.901), the duration of intraoperative administered nasogastric tube (NGT) (p = 0.812), the rate of re-insertion of NGT (p = 0.072), and the need for parenteral nutrition (p = 0.643) did not differ. However, patients with LC and advanced LF showed a higher ASA (American Society of Anesthesiologists) score (p = 0.016), intraoperatively received more erythrocyte transfusions (p = 0.029), stayed longer in the intensive care unit (p = 0.010) and showed more intraabdominal abscess formation (p = 0.006). Moreover, we did observe a higher mortality rate amongst patients with pre-existing liver diseases (p = 0.021), and reoperation was a risk factor for higher mortality (p ≤ 0.001) in the multivariate analysis. In our study, we could not detect a difference with respect to DGE classified by ISGPS, however, we did observe a higher mortality rate amongst these patients and thus, they should be critically evaluated for PD.
Published: 2021

49. Professionalizing the information security of family firms: A family essence perspective

Author: Tim R. Barnett, Ziyi Niu, and Kent Marett
Subjects: Family business, business.industry, Strategy and Management, 05 social sciences, Perspective (graphical), Information security, Public relations, General Business, Management and Accounting, Professionalization, Management of Technology and Innovation, 0502 economics and business, 050211 marketing, Business, Business function, 050203 business & management
Abstract: Family firm leaders are often faced with conflicting pressures and goals. One such situation occurs when deciding whether to pursue professionalized management of a business function as opp...
Published: 2019

50. Safety of 6-week Neonatal Triple-combination Antiretroviral Postexposure Prophylaxis in High-risk HIV-exposed Infants

Author: Thanyawee Puthanakit, Kulkanya Chokephaibulkit, Tim R. Cressey, Sunti Punnahitanon, Watsamon Jantarabenjakul, Pradthana Ounchanum, Chitsanu Pancharoen, Jiratchaya Sophonphan, Suvaporn Anugulruengkitt, Piyarat Suntarattiwong, and Ussanee Srirompotong
Subjects: Male, Microbiology (medical), Pediatrics, medicine.medical_specialty, Nevirapine, Drug-Related Side Effects and Adverse Reactions, HIV Infections, Chemoprevention, 03 medical and health sciences, Zidovudine, 0302 clinical medicine, Pharmacotherapy, immune system diseases, 030225 pediatrics, medicine, Triple combination, Humans, Prospective Studies, 030212 general & internal medicine, Adverse effect, Prospective cohort study, Transmission (medicine), business.industry, Infant, Newborn, Infant, virus diseases, Lamivudine, Thailand, Infectious Disease Transmission, Vertical, Treatment Outcome, Infectious Diseases, Anti-Retroviral Agents, Pediatrics, Perinatology and Child Health, Drug Therapy, Combination, Female, Post-Exposure Prophylaxis, business, medicine.drug
Abstract: Combination antiretroviral drug regimens are increasingly preferred for neonatal postexposure prophylaxis (PEP) among HIV-exposed infants with high-risk of transmission. We evaluated the adverse events associated with the use of zidovudine (ZDV)/lamivudine (3TC)/nevirapine (NVP) for neonatal PEP during the first 6 weeks of life.A prospective cohort of non-breast-fed HIV-exposed infants was conducted at 5 clinical sites in Thailand. Study population included 100 high-risk HIV-exposed infants (maternal HIV RNA50 copies/mL prior to delivery or received antiretroviral therapy less than 12 weeks) and 100 low-risk HIV-exposed neonates. High-risk infants received ZDV/3TC/NVP for 6 weeks whereas low-risk HIV-exposed neonates received a 4-week regimen of ZDV. Complete blood count, aspartate transaminase and alanine transaminase were assessed at birth, 1, 2 and 4 months of life.From October 2015 to November 2017, 200 infants were enrolled, of which 18.5% had low birth weight2500 g. The proportion of infants with anemia grade 2 or higher at 1 and 2 months of life between ZDV/3TC/NVP and ZDV prophylaxis was 48.5% vs 32.3% (P=0.02); nevertheless, severe anemia (grade 3) was not significantly different; 9.2% vs 10.2% (P=0.81), respectively. At 1 month old, infants on ZDV/3TC/NVP prophylaxis had significantly higher grade 2 anemia versus infants on ZDV alone (33.0% vs 13.4%; P=0.001); however, no difference was observed at 2 months old. No differences in neutropenia or hepatotoxicity between infant prophylactic regimens were observed.Triple antiretroviral neonatal PEP with ZDV/3TC/NVP for 6 weeks in high-risk HIV-exposed infants did not significantly increase the risk of short-term toxicity compared with ZDV-monotherapy prophylaxis.
Published: 2019

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