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2. Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG
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Subodh Verma, Deepak L. Bhatt, Ph. Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Nitish K. Dhingra, Steven B. Ketchum, Rebecca A. Juliano, Lixia Jiao, Ralph T. Doyle, Craig Granowitz, C. Michael Gibson, Duane Pinto, Robert P. Giugliano, Matthew J. Budoff, R. Preston Mason, Jean-Claude Tardif, Christie M. Ballantyne, Fabrice M.A.C. Martens, Astrid Schut, Brian Olshansky, Mina Chung, Al Hallstrom, Lesly Pearce, Cyrus Mehta, Rajat Mukherjee, Anjan K. Chakrabarti, Eli V. Gelfand, Megan Carroll Leary, Duane S. Pinto, Yuri B. Pride, Steven Ketchum, Ramakrishna Bhavanthula, Gertrude Chester, Christina Copland, Katelyn Diffin, Ralph Doyle, Kurt Erz, Alex Giaquinto, Paula Glanton, Angela Granger, Richard H. Iroudayassamy, Rebecca Juliano, James Jin, Dimitry Klevak, Hardik Panchal, Robert Wang, Shin-Ru Wang, Gerard Abate, Peggy J. Berry, Rene Braeckman, Declan Doogan, Anne Elson, Amy HauptmannBaker, Isabel Lamela, Catherine Lubeck, Mehar Manku, Sabina Murphy, Monica Sanford, William Stirtan, Paresh Soni, Arnaud Bastien, Demetria Foster, Evangelito Gascon, Judith Johnson, Lasbert Latona, Gang Liu, Sandra Palleja, Nelly Sanjuan, Jimmy Shi, William Stager, Mukund Venkatakrishnan, Ahmed Youssef-Agha, Julie Zhu, Leela Aertker, Suresh Ankolekar, Lisa Goldberg, Natasa Rajicic, Jianfen Shu, Heng Zou, Magdy Mikhail, Gamil Dawood, N. Mathew Koshy, Sandip K. Mukherjee, Rafik Abadier, Andrea L. Lawless, William P. McGuinn, Howard Weintraub, Kathryn Rohr, Edmund Claxton, Robert J. Weiss, Terry D. Klein, Mani Nallasivan, Stephen Crowley, Marilyn King, Anthony D. Alfieri, David Fitz-Patrick, Irving Loh, Nolan J. Mayer, Rakesh Prashad, Samuel Lederman, Debra Weinstein, Harold E. Bays, Keith Chu, Alireza Maghsoudi, Paul D. Thompson, Jeff Carstens, Anna Chang, Kenneth R. Cohen, Julius Dean, Howard S. Ellison, Bernard Erickson, Enrique A. Flores, Daniel W. Gottlieb, Paul Grena, John R. Guyton, Peter H. Jones, John M. Joseph, Norman E. Lepor, Sam Lerman, Robert D. Matheney, Theodore R. Pacheco, Michael B. Russo, John Rubino, Edward S. Pereira, Albert A. Seals, Eduardo Viera, Alan D. Steljes, Jason Thompson, Shaival Kapadia, Michael McIvor, Jorge E. Salazar, Jose O. Santiago, Ralph Vicari, Martin R. Berk, William A. Kaye, Marcus McKenzie, David Podlecki, Brian D. Snyder, Stephen Nash, David M. Herrington, Wallace Johnson, Joseph R. Lee, Ronald Blonder, Alpa M. Patel, Ramon Castello, Susan Greco, Dean J. Kereiakes, Venkatesh K. Nadar, Mark Nathan, Ranganatha P. Potu, Robert Sangrigoli, Richard Smalling, Mitchell Davis, Robert Braastad, James McCriskin, Kunal Bodiwala, Joe L. Hargrove, Mark W. Graves, George Emlein, Raegan W. Durant, James W. Clower, Rohit Arora, Narendra Singh, Lisa Warsinger Martin, W Herbert Haught, Marc P. Litt, Michael D. Klein, Peter Hoagland, Michael Goldstein, Marco S. Mazzella, Daniel H. Dunker, Brian H. Kahn, Carlos S. Ince, Frank A. McGrew, Jay Lee, David Pan, Salman A. Khan, Uri Elkayam, Wasim Deeb, Anne C. Goldberg, Christopher S. Brown, Wayne N. Leimbach, Thomas S. Backer, David R. Sutton, Joel Gellman, Anu R. George, Alan S. Hoffman, Mark Kates, Kishlay Anand, Robert Bear, Brendan J. Cavanaugh, Ramon G. Reyes, Rodolfo Sotolongo, Kenneth Sabatino, Kevin Gallagher, Ehab Sorial, Chris Geohas, Kathleen E. Magness, Bernard P. Grunstra, Frederik A. Martin, William S. Knapp, Mel E. Lucas, John J. Champlin, Jason Demattia, Patrick H. Peters, Judith Kirstein, William J. Randall, Cezar S. Staniloae, Jennifer G. Robinson, Alexander Adler, Christopher Case, Andrew J. Kaplan, Gregory F. Lakin, Krishan K. Goyle, Michael J. DiGiovanna, Chester L. Fisher, Michael Lillestol, Michael Robinson, Robert G. Perry, Lawrence S. Levinson, Brian G. Everhart, Robert D. Madder, Earl F. Martin, Earl E. Martin, Imtiaz Alam, Jose Mari L. Elacion, Robina Poonawala, Taddese T. Desta, Jerome A. Robinson, Gilbert J. Martinez, Jakkidi S. Reddy, Jeffrey D. Wayne, Samuel Mujica Trenche, Westbrook I. Kaplan, Rubin H. Saavedra, Michael D. DiGregorio, Barry D. Bertolet, Neil J. Fraser, Terence T. Hart, Ronald J. Graf, David A. Jasper, Michael Dunn, Dan A. Streja, David J. Strobl, Nan Jiang, Vicki Kalen, Richard Mascolo, Mercedes B. Samson, Michael Stephens, Bret M. Bellard, Mario Juarez, Patrick J. McCarthy, John B. Checton, Michael Stillabower, Edward Goldenberg, Amin H. Karim, Naseem Jaffrani, Robert C. Touchon, Erich R. Fruehling, Clayton J. Friesen, Pradipta Chaudhuri, Frank H. Morris, Robert E. Broker, Rajesh J. Patel, Susan Hole, Randall P. Miller, Francisco G. Miranda, Sadia Dar, Shawn N. Gentry, Paul Hermany, Charles B. Treasure, Miguel E. Trevino, Raimundo Acosta, Anthony Japour, Samuel J. Durr, Thomas Wang, Om P. Ganda, Perry Krichmar, James L. Arter, Douglas Jacoby, Michael A. Schwartz, Amer Al-Karadsheh, Nelson E. Gencheff, John A. Pasquini, Richard Dunbar, Sarah Kohnstamm, Hector F. Lozano, Francine K. Welty, Thomas L. Pitts, Brian Zehnder, Salah El Hafi, Mark A. King, Arnold Ghitis, Marwan M. Bahu, Hooman Ranjbaran Jahromi, Ronald P. Caputo, Robert S. Busch, Michael D. Shapiro, Suhail Zavaro, Munib Daudjee, Shahram Jacobs, Vipul B. Shah, Frank Rubalcava, Mohsin T. Alhaddad, Henry Lui, Raj T. Rajan, Fadi E. Saba, Mahendra Pai N Gunapooti, Tshiswaka B. Kayembe, Timothy Jennings, Robert A. Strzinek, Michael H. Shanik, Pradeep K. Singh, Alastair C. Kennedy, Howard Rubenstein, Ramin Manshadi, Joanne Ladner, Lily Kakish, Ashley Kakish, Amy L. Little, Jaime Gerber, Nancy J. Hinchion, Janet Guarino, Denise Raychok, Susan Budzinski, Kathleen Kelley-Garvin, April Beckord, Jessica Schlinder, Arthur Schwartzbard, Stanley Cobos, Deborah Freeman, David Abisalih, Dervilla McCann, Kylie Guy, Jennifer Chase, Stacey Samuelson, Madeline Cassidy, Marissa Tardif, Jaime Smith, Brenna Sprout, Nanette Riedeman, Julie Goza, Lori Johnson, Chad Kraske, Sheila Hastings, Chris Dutka, Stephanie Smith, Toni McCabe, Kathleen Maloney, Paul Alfieri, Vinay Hosemane, Chanhsamone Syravanh, Cindy Pau, April Limcoiloc, Tabitha Carreira, Taryn S. Kurosawa, Razmig Krumian, Krista Preston, Ashraf Nashed, Daria Schneidman-Fernandez, Jack Patterson, John Tsakonas, Jennifer Esaki, Lynn Sprafka, Porous Patel, Brian Mitchell, Erin M. Ross, Donna Miller, Akash Prashad, Kristina M. Feyler, Natasha Juarbe, Sandra Herrera, Sarah M. Keiran, Becky Whitehead, Whitney Asher, Coury Hobbs, Abbey Elie, Jean Brooks, Amanda L. Zaleski, Brenda Foxen, Barb Lapke, Philippa Wright, Bristol Pavol, Gwen Carangi, Marla Turner, Katharine W. Sanders, Rikita S. Delamar, Virginia L. Wilson, Sarah M. Harvel, Alison M. Cartledge, Kaitlyn R. Bailey, Kathleen Mahon, Timothy Schuchard, Jen Humbert, Mark C. Hanson, Michael P. Cecil, James S. Abraham, Lorie Benedict, Claudia Slayton, Curtis S. Burnett, Rachel W. Ono-Lim, Sharon Budzinski, Shubi A. Khan, Sharon Goss, Terry Techmanski, Farida Valliani, Rimla Joseph, Edith Flores, Laurn Contreras, Ana Aguillon, Carrie-Ann Silvia, Maria Martin, Edmund K. Kerut, Leslie W. Levenson, Louis B. Glade, Brian J. Cospolich, Maureen W. Stein, Stephen P. LaGuardia, Thelma L. Sonza, Tracy M. Fife, Melissa Forschler, Jasmyne Watts, Judy Fritsch, Emese Futchko, Sarah Utech, Scott B. Baker, Miguel F. Roura, Scott A. Segel, James S. Magee, Cathy Jackson, Rebecca F. Goldfaden, Liudmila Quas, Elizabeth C. Ortiz, Michael Simpson, Robert Foster, Christopher Brian, James Trimm, Michael Bailey, Brian Snoddy, Van Reeder, Rachel Wilkinson, Harold Settle, Cynthia Massey, Angela Maiola, Michele Hall, Shelly Hall, Wanda Hall, Mark Xenakis, Janet Barrett, Giovanni Campanile, David Anthou, Susan F. Neill, Steven Karas, Enrique Polanco, Norberto Schechtman, Grace Tischner, Kay Warren, Cynthia St Cyr, Menna Kuczinski, Latrina Alexander, Maricruz Ibarra, Barry S. Horowitz, Jaime Steinsapir, Jeanette Mangual-Coughlin, Brittany Mooney, Precilia Vasquez, Kathleen Rodkey, Alexandria Biberstein, Christine Ignacio, Irina Robinson, Marcia Hibberd, Lisa B. Hoffman, Daniel J. Murak, Raghupathy Varavenkataraman, Theresa M. Ohlson Elliott, Linda A. Cunningham, Heather L. Palmerton, Sheri Poole, Jeannine Moore, Helene Wallace, Ted Chandler, Robert Riley, Farah Dawood, Amir Azeem, Michael Cammarata, Ashleigh Owen, Shivani Aggarwal, Waqas Qureshi, Mohamed Almahmoud, Abdullahi Oseni, Adam Leigh, Erin Barnes, Adam Pflum, Amer Aladin, Karen Blinson, Vickie Wayne, Lynda Doomy, Michele Wall, Valerie Bitterman, Cindi Young, Rachel Grice, Lioubov Poliakova, Jorge Davalos, David Rosenbaum, Mark Boulware, Heather Mazzola, J. Russell Strader, Russell Linsky, David Schwartz, Elizabeth Graf, Alicia Gneiting, Melissa Palmblad, Ashley Donlin, Emily Ensminger, Hillary Garcia, Dawn Robinson, Carolyn Tran, Jeffrey Jacqmein, Darlene Bartilucci, Michael Koren, Barbara Maluchnik, Melissa Parks, Jennifer Miller, Cynthia DeFosse, Albert B. Knouse, Amy Delancey, Stephanie Chin, Thomas Stephens, Mag Sohal, Juana Ingram, Swarooparani Kumar, Heather Foley, Nina Smith, Vera McKinney, Linda Schwarz, Judith Moore, Hildreth Vernon Anderson, Stefano Sdringola-Maranga, Ali Denktas, Elizabeth Turrentine, Rhonda Patterson, John Marshall, Terri Tolar, Donna Patrick, Pamela Schwartzkopf, Anthony M. Fletcher, Frances R. Harris, Sherry Clements, Tiffany Brown, William Smith, Stacey J. Baehl, Robin Fluty, Daniel VanHamersveld, Dennis Breen, Nancy Bender, Beverly Stafford, Tamika Washington, Margaret N. Pike, Mark A. Stich, Evyan Jawad, Amin Nadeem, Jill Nyland, Rhonda Hamer, Kendra Calhoun, Charlotte Mall, Samuel Cadogan, Kati Raynes, Richard Katz, Lorraine Marshall, Rashida Abbas, Jay L. Dinerman, John T. Hartley, Beth Lamb, Lisa Eskridge, Donna Raymond, Kristy Clemmer, Denise M. Fine, Paula Beardsley, Janet Werner, Bette Mahan, Courtney VanTol, Robert Herman, Christine Raiser-Vignola, Felicia McShan, Stefanie A. Neill, David R. Blick, Michael J. Liston, Denetta K. Nelson, Sandra K. Dorrell, Patricia Wyman, Ambereen Quraishi, Fernando Ferro, Frank Morris, Vicki J. Coombs, Autumn M. Mains, Austin A. Campbell, Jeanne Phelps, Cheryl A. Geary, Ellen G. Sheridan, Jean M. Downing, Arie Swatkowski, Tish Redden, Brian Dragutsky, Susan Thomas, Candace Mitchell, Diana Barker, Elanie Turcotte, Deborah Segerson, Jill Guy, Karena De La Mora, Jennifer Hong, Dennis Do, Rose Norris, Faisal Khan, Hector Montero, Stacy Kelly-White, Alan Cleland, Rosalyn Alcalde-Crawford, Melissa Morgan, Brijmohan Sarabu, Megan Minor, Shweta Kamat, Stephanie M. Estes, Nancee Harless, Alicia Disney, Jodi L. Pagano, Chad M. Alford, Noel W. Bedwell, Warren D. Hardy, Kevin DeAndrade, Jessica G. Elmore, Eric Auerbach, Anthony W. Haney, Miriam H. Brooks, Jose Torres, Lois Roper, Terry Backer, Katie Backer, John G. Evans, Ricardo A. Silva, Lorraine H. Dajani, Veronica Yousif, Tammy Ross, Sion K. Roy, Ronald Oudiz, Sajad Hamal, Ferdinand Flores, Amor Leahy, Debra Ayer, Swapna George, Chrisi Carine Stewart, Elvira Orellana, Cristina Boccalandro, Mary Rangel, Suzanne Hennings, Carl Vanselow, Teri Victor, Darlene Birdwell, Paul Haas, Anthony Sandoval, Gina Ciavarella, Caroline Saglam, Amy Bird, Keith Beck, Brian Poliquin, David Dominguez, Brittany Tenorio, Harvonya Perkins, Esther San Roman, Paris Bransford, Christy Lowrance, Marcy Broussard, Mary Ellis, Bobbi Skiles, Jessica Hamilton, Kathryn Hall, Diego Olvera, Julee A. Hartwell, Nevien Sorial, Mary Rickman, Kevin Berman, Nirav Mehta, Annie Laborin, Rodger Rothenberger, Sarah Beauvilliers, Kathy Morrell, Michael P. Schachter, Cindy L. Perkins, Elizabeth A. Gordon, Jennifer Lauer, Kim Bichsel, Kelly Oliver, Leslie J. Mellor, Candice Demattia, Jennifer Schomburg, Yenniffer Moreno, Eduardo Mansur-Garza, Lena Rippstein, Lorie Chacon, Andrea Pena, Michelle King, Susan Richardson, Annette Jessop, Nicole Tucker, Whitney Royer, Gilbert Templeton, Ann Moell, Christine Weller, Melissa J. Botts, Gretel Hollon, Elsa Homberg-Pinassi, Paula Forest, Aref Bin Abhulhak, Devona Chun-Furlong, Deborah Harrington, Emily Harlynn, Marjorie Schmitt, Constance Shelsky, Patricia Feldick, Mary Cherrico, Courtney Jagle, Nicholas Warnecke, Debra Myer, Deanna J. Ruder, Albina Underwood, Alan Rauba, George Carr, Barbara Oberhaus, Jessica Vanderfeltz, Mary Jo Stucky-Heil, Dale R. Gibson, Vonnie Fuentes, Kimberly L. Talbot, William C. Simon, Katlyn J. Grimes, Christina R. Wheeler, Cassaundra Shultz, Rhonda A. Metcalf, Jennifer L. Hill, Michelle R. Oliver, Basharat Ahmad, Fouzal Azeem, Abdul Rahim, George H. Freeman, Dawn Bloch, Heather Freeman, Jamie Brown, Sarah Rosbach, Pamela Melander, Nick Taralson, Alex Liu, Katlyn Harms, Mahfouz Michale, Jose Lopez, Maria Revoredo, Shari Edevane, Sarah Shawley, Timothy L. Jackson, Michael J. Oliver, Dina DeSalle, Patricia J. Matlock, Ionna M. Beraun, Heather Hendrix, Garrett Bromley, Ashley Niemerski, Gabby Teran, Sonia Guerrero, Murtaza Marvi, Zehra Palanpurwala, Andrea Torres, Patty Gloyd, Michelle Conger, Aziz Laurent, Olia Nayor, Catalina S. Villanueva, Munira Khambati, Tabetha J. Mumford, Melanie J. Castillo, Taddese Desta, Jerome Robinson, La Shawn Woods, Anita Bahri, Nancy Herrera, Cecilia Casaclang, Jeffrey R. Unger, Geraldine Martinez, Mia K. Moon, Stephen M. Mohaupt, Larry Sandoval, Louisito Valenzuela, Victora Ramirez, Nelly Mata, Veronica Avila, Marisol Patino, Cynthia Montano-Pereira, Omar Barnett, William M. Webster, Lorraine M. Christensen, Leighna Bofman, Melanie Livingston, Stacey Adams, Joseph Hobbs, Leesa Koskela, Mia Katz, Samuel Mujica-Trenche, Franklin Cala, Noreen T. Rana, Jennifer Scarlett, Milagros Cala Anaya, Marsha R. Jones, Kelly D. Hollis, Debbie Roth, Kristin Eads, Tina Watts, Judy Perkins, Alice Arnold, Daniel C. Ginsberg, Denise Quinn, Nicole Cureton, David B. Fittingoff, Mohammed I. Iqbal, Stephen R. White, Edith Sisneros, Michelle Ducca, David Streja, Danny Campos, Jennifer L. Boak, Farzeen Amir, Felice Anderson, James J. Kmetzo, Mary O. Bongarzone, Dawn Scott, Mary Grace De Leon, Cynthia Buda, William Graettinger, Michelle Alex, Erika Hess, James Govoni, Melissa Bartel, Travis L. Monchamp, Julie S. Roach, Sara Gibson, Amy M. Allfrey, Kristen Timpy, Kathy Bott, Karin A. Soucy, Jean Willis, Cecilia A. Valerio, Anusha Chunduri, Rebecca Coker, Nicole Vidrine, Ellen A. Thompson, Mark A. Studeny, Melissa K. Marcum, Tammy S. Monway, Douglas L. Kosmicki, Melissa J. Kelley, Corey M. Godfrey, Susan L. Krenk, Randy R. Holcomb, Deb K. Baehr, Mary K. Trauernicht, David Rowland Lowry, Betty Bondy Herts, Jeanne E Phelps, Jean-Marie Downing, Carol Gamer Dignon, Elisabeth S. Cockrill, Pravinchandra G. Chapla, Diane Fera, Margaret Chang, Patricia Fredette, Tamie Ashby, Renee Bergin, Zebediah A. Stearns, David B. Ware, Rachael M. Boudreaux, Joanna Rodriguez, Robert McKenzie, Amanda Huber, Rebecca Sommers, Heather Rowe, Stacy McLallen, Michale Haynes, Ashley Adamson, Janice Henderson, Lori McClure, Beverly A. Harris, Laura Ference, Sue Meissner-Dengler, Lisa Treasure, Doreen Nicely, Timothy L. Light, Tracey A. Osborn, Kimberly J. Mai, Pablo Vivas, Jose Rios, Dunia Rodriguez, Roger DeRaad, James Walder, Oscar Bailon, Denice Hockett, Debbie Anderson, Kelli McIntosh, Amber Odegard, Andrew Shepherd, Mary Seifert, Laurence Kelley, Rajendra Shetty, Michael Castine, David Brill, Gregory Fisher, Nicole Richmond, Kathleen Gray, Patricia Miller, Charlene Coneys, Yarixa Chanza, Monica Sumoza, Victoria M. Caudill, Kelly D. Harris, Courtney A. Manion, Melody J. Lineberger-Moore, Julie J. Wolfe, Barbara J. Rosen, Patricia DiVito, Janet L. Moffat, Christina Michaelis, Prashant Koshy, Diana Perea, Ghaith Al Yacoub, Stephanie Sadeghi, Thomas D. LeGalley, Rudolph F. Evonich, William J. Jean, Gary M. Friesen, John M. Pap, David A. Pesola, Mark D. Cowan, Kristofer M. Dosh, Dianna Larson, Adele M. Price, Jodi A. Nease, Jane E. Anderson, Lori A. Piggott, Robert Iwaoka, Kevin Sharkey, Edward McMillan, Laurie Lowder, Latisha Morgan, Kyle Davis, Tara Caldwell, Erica Breglio, Jasmine Summers, Rachel Poulimas, Muhammad Zahid, Hamid Syed, Maria Escobar, Jacob Levy, Rahma Warsi, Carol Ma, Puxiao Cen, Kimberly A. Cawthon, Delores B. Barnes, Deanna G. Allen, Margaret L. Warrington, Carol R. Stastny, Robin J. Michaels, Mohamad Saleh, John Sorin, Sunny Rathod, Urakay Juett, Steven Spencer, Aziza Keval, Jill McBride, Shane Young, Catherine Baxter, Carol Rasmussen, Shari L. Coxe, Luis Campos, Shahin Tavackoli, Diana Beckham, Darlynee Sanchez, Karanjit Basrai, Dorian Helms, Erica Clinton, Kasie Smith, Henry Cusnir, Mary Klaus Clark, Madhavagopal V. Cherukuri, Ameta Scarfaru, Stephen D. Nash, Loretta C. Grimm, Anna Grace, Kylie McElheran, Dino Subasic, Zedrick Buhay, Janet Litvinoff, Deepak Shah, Shannon Cervantes, Freda Usher, Farra Yasser, Theodore Trusevich, Ronnie L. Garcia, Jamison Wyatt, Rahul Bose, Holllilyn Miska, Traci Spivey, Amy B. Wren, Katie E. Vance, Lani L. Holman, Pam Gibbons, Elaine Eby, Sandra Shepard, Soratree Charoenthongtrakul, Brett Snodgrass, Mohammed Nazem, Shelly Keteenburg, Prathima Murthy, Frederic Prater, Ashley Rumfelt, Christina Eizensmits, Lisa Iannuzzi, Pourus R. Patel, Clellia Bergamino, Elizabeth McFeaters, Botros Rizk, Emiljia Pflaum, Danny Kalish, Rex Ambatali, Mona Ameli, Delaina Sanguinetti, Rakesh Vaidya, Martinus A.W. Broeders, Dorman Henrikus, Adrianus F.M. Kuijper, Nadea Al-Windy, Michael Magro, Karim Hamraoui, Ismail Aksoy, Guy L.J. Vermeiren, H.W.O. Roeters van Lennep, Gerard Hoedemaker, Johannes Jacobus Remmen, Kjell Bogaard, Dirk van der Heijden, Nicole MJ Knufman, Joost Frederiks, Johannes Willem Louwerenburg, Piet van Rossum, Johannes Milhous, Peter van der Meer, Arno van der Weerdt, Rob Breedveld, Mitran Keijzers, Walter Hermans, Ruud van de Wal, Peter A.G. Zwart, Marc M.J.M. van der Linden, Gerardus Zwiers, Dirk J. Boswijk, Jan Geert Tans, Jacob van Eck, Maarten V. Hessen, Barnabas J.B. Hamer, Stieneke Zoet-Nugteren, Lucien Theunissen, E.A. van Beek, Remco Nijmeijer, Pieter R. Nierop, Gerard Linssen, H.P. Swart, Timo Lenderink, Gerard L. Bartels, Frank den Hartog, Brian J. Berg van den, Wouter van Kempen, Susanne Kentgens, Gloria M. Rojas Lingan, Martinus M. Peeters, Hilligje Keterberg, Melchior Nierman, Annemieke K. den Hollander, Jacqueline Hoogendijk, Christine Voors-Pette, Vicdan Kose, Peter Viergever, Larysa Yena, Viktor Syvolap, Mykola P. Kopytsya, Olga Barna, Svitlana S. Panina, Mykhailo I. Lutai, Oxana V. Shershnyova, Iryna Luzkiv, Larysa S. Bula, Sergii Zotov, Ivan Vyjhovaniuk, Olena Lysunets, Volodymyr I. Koshlia, Nataliya Sydor, Myroslava F. Vayda, Olexiy Ushakov, Mykola Rishko, Viktor P. Shcherbak, Yevgeniya Svyshchenko, Vira Tseluyko, Andriy Yagensky, Viktoriia I. Zolotaikina, Olga Godlevska, Larysa Ivanova, Olena Koval, Olena I. Mitchenko, Galyna Y. Kardash, Yurii S. Rudyk, Mykola Stanislavchuk, Volodymyr Ivanovych Volkov, Olena G. Karlinskaya, Susanna A. Tykhonova, Nikolay Vatutin, Ganna Smirnova, Volodymyr M. Kovalenko, Viktor Lizogub, Denys Sebov, Oleksandr Dyadyk, Svetlana Andrievskaya, Mykola P. Krasko, Alexander N. Parkhomenko, Lidiya Horbach, Iryna G. Kupnovytska, Tetyana Pertseva, Oleksandr Karpenko, Dmytro Reshotko, Svitlana V. Zhurba, Leonid Rudenko, Viktoriia Yu Zharinova, Valerii B. Shatylo, Yuriy I. Karpenko, Mariya A. Orynchak, Tatiana R. Kameneva, Elena Zherlitsina, Diana N. Alpenidze, Grigoriy P. Arutyunov, Elena Baranova, Boris Bart, Dmitriy I. Belenkiy, Svetlana A. Boldueva, Elena A. Demchenko, Vera V. Eltishcheva, Alexander M. Gofman, Boris M. Goloshchekin, Ivan Gennadyevich Gordeev, Nikolay Gratsianskiy, Gadel Kamalov, Niyaz R. Khasanov, Irina M. Kholina, Zhanna D. Kobalava, Elena V. Kobeleva, Alexandra O. Konradi, Victor A. Kostenko, Andrey Dmitrievich Kuimov, Polina Y. Ermakova, Sofia K. Malyutina, Alexey V. Panov, Natalia V. Polezhaeva, Olga Reshetko, Nataliya P. Shilkina, Sergey B. Shustov, Elena A. Smolyarchuk, Raisa I. Stryuk, Elena Yurievnar Solovieva, Andrey V. Susekov, Natalia Vezikova, Svetlana N. Ivanova, Alexander A. Petrov, Vladimir O. Konstantinov, Alina S. Agafina, Victor Gurevich, Konstantin N. Zrazhevskiy, Tatiana V. Supryadkina, Nikita B. Perepech, Vadim L. Arkhipovskiy, Dmitry Yu Butko, Irina A. Zobenko, Olga V. Orlikova, Viktor Mordovin, Olga L. Barbarash, Anastasiya Lebedeva, Vladimir Nosov, Oleg V. Averkov, Elena P. Pavlikova, Yuri B. Karpov, Marina Lvovna Giorgadze, Oleg A. Khrustalev, Mikhail Arkhipov, Tatiana A. Raskina, Julia V. Shilko, Yulia Samoilova, Elena D. Kosmacheva, Sergey V. Nedogoda, Kathleen Coetzee, Lesley J. Burgess, F.C.R. Theron, Iftikhar O. Ebrahim, Gerbrand A. Haasbroek, Maria Pretorius, Julien S. Trokis, Dorothea V. Urbach, Mark J. Abelson, Adrian R. Horak, Aysha E. Badat, Ellen M. Makotoko, Hendrik Du Toit Theron, Padaruth Ramlachan, Clive H. Corbett, Ismail H. Mitha, Hendrik F.M. Nortje, Dirkie J. Jansen van Rensburg, Peter J. Sebastian, F.C.J. Bester, Louis J. van Zyl, Brian L. Rayner, Elżbieta Błach, Magda Dąbrowska, Grzegorz Kania, Agata E. Kelm-Warchol, Leszek P. Kinasz, Janusz Korecki, Mariusz Kruk, Ewa Laskowska-Derlaga, Andrzej Madej, Krzysztof Saminski, Katarzyna Wasilewska, Katarzyna Szymkowiak, Małgorzata Wojciechowska, Natalia Piorowska, Andrzej Dyczek, Rajpal K. Abhaichand, Ramesh B. Byrapaneni, Basavanagowdappa Hattur, Malipeddi Bhaskara Rao, Nitin Ghaisas, Sujit Shankar Kadam, Jugal B. Gupta, Santhosh M. Jayadev, V.A. Kothiwale, Atul Mathur, Vijay Bhaskar, Ravi K. Aluri, Udaya P. Ponangi, Mukesh K. Sarna, Sunil Sathe, Manish K. Sharma, Jilendra Pal Singh Sawhney, Chakrabhavi B. Keshavamurthy, Arun Srinivas, Hemant P. Thacker, A. Sharda, Johny Joseph, Sunil Dwivedi, Viswanathan Mohan, Rajendra K. Premchand, Jacques Bedard, Jean Bergeron, Ronald Collette, David Crowley, Richard Dumas, Sam Henein, Geoff Moran, William F. O’Mahony, Michael O’Mahony, Sammy Chan, Mark H. Sherman, Graham C. Wong, Brian D. Carlson, Milan K. Gupta, David Borts, Sean R. Peterson, Martyn Chilvers, Allan J. Kelly, Jean C. Gregoire, Simon Kouz, Josep Rodés Cabau, Minodora Andor, Mircea Cinteza, Radu Ciudin, Radu I. Cojan, Roxana O. Darabont, Dan-Lucian Dumitrascu, Carmen Fierbinteanu-Braticievici, Ana Gabriela Fruntelata, Constantin Militaru, Bogdon E. Minescu, Doina Luminita Serban, Florin Mitu, Dorel Nastase Melicovici, Ovidiu Petrascu, Octavian M. Pirvu, Cristian Podoleanu, Calin Pop, Rodica-Valentina V. Stanescu-Cioranu, Adrian Tase, Cristina Voiculet, Constantine N. Aroney, Anthony M. Dart, Timothy Davis, Karam Kostner, David N. O’Neal, Peter W. Purnell, Bhuwanendu B. Singh, David R. Sullivan, Peter Thompson, Gerald F. Watts, Adam F. Blenkhorn, John V. Amerena, Rafeeq Samie, Randall Hendriks, Joseph Proietto, Nikolai Petrovsky, Alan Whelan, David Colquhoun, Russell S. Scott, Simon C. Young, Tammy Pegg, Samuel JS Wilson, Andrew W. Hamer, Richard A. Luke, Hamish H. Hart, Gerard P. Devlin, Gerard T. Wilkins, Ian F. Ternouth, Samraj Nandra, Bruno S. Loeprich, Nicole McGrath, Stuart L. Tie, Rob J. Bos, Alexandra Wils, Tamara Jacobs, Erik A. Badings, Lillian A. Ebels-Tuinbeek, Mayke L. Scholten, Esther Bayraktar-Verver, Debby Zweers, Manoek Schiks, Carolien Kalkman, Tineke Tiemes, Jeanette Mulderij, Katarzyna Dabrowska, Wilma Wijnakker, Riny Van de Loo, Jeanne de Graauw, Giny Reijnierse, Mirjam van der Zeijst, Mariska Scholten, Henk R. Hofmeijer, Antoinette van Dijk-van der Zanden, Dineke J. van Belle, Jan Van Es, Gera Van Buchem, Wendy Zijda, Harald Verheij, Linnea Oldenhof-Janssen, Martina Bader, Marije Löwik, Sandra Stuij, Pascal Vantrimpont, Krista van Aken, Karen Hamilton, Han Blömer, Gabriela van Laerhoven, Raymond Tukkie, Maarten Janssen, Gerard Verdel, Jon Funke Küpper, Bob van Vlies, Caroline Kalkman, Joke Vooges, Marinella Vermaas, Rachel Langenberg, Niek Haenen, Frans Smeets, Arko Scheepmaker, Marcel Grosfeld, Ilvy Van Lieshout, Marleen van den Berg, Marian Wittekoek, Petra Mol, Antionette Stapel, Margaretha Sierevogel, Nancy van der Ven, Annemiek Berkelmans, Eric Viergever, Hanneke Kramer, Wilma Engelen, Karen V. Houwelingen, Thierry X. Wildbergh, Arend Mosterd, Coriet Hobé-Rap, Marjan van Doorn, Petra Bunschoten, Michel Freericks, Mireille Emans, Petra Den Boer-Penning, Els Verlek, Christine Freericks, Cornelis de Nooijer, Christina Welten, Ingrid Groenenberg, Claudia van der Horst, Esther Vonk, Geert Tjeerdsma, Gerard M. Jochemsen, Corinne van Daalen, Ingrid Y. Danse, Lucy Kuipers, Anke Pieterse, Antonius Oomen, Daan de Waard, Willem Jan Flu, Zusan Kromhout, Petra Van der Bij, Rob Feld, Brigitta Hessels-Linnemeijer, Rob Lardinois, Jan L. Posma, Zwanette R. Aukema-Wouda, Marjolijn Hendriks-van Woerden, Desiree van Wijk, Driek P. Beelen, Ingrid H. Hendriks, Jan J. Jonker, Stefanie Schipperen, Vicdan Köse, Gloria Rojas, Linda Goedhart, Hanneke van Meurs, Jacqueline Rijssemus, Lindy Swinkels-Diepenmaat, Marloes de Louw-Jansen, Dominique Bierens-Peters, Willem W. van Kempen, Marianne E. Wittekoek, Irmaina Agous, Geert Schenk, Janneke Wittekoek, Kevin Cox, Deborah F. Julia, Jan J.C. Jonker, Roel Janssen, Melchor Nierman, Hilligje Katerberg, Irene van der Haar, Willem W. Van Kempen, Taco van Mesdag, Leyda M. Alvarez Costa, Manon Schensema, Salomé Zweekhorst, Deborah Font Julia, Lauri Hanewinckel, Joyce Olsthoorn, Johan C. Berends, Arie C. van der Spek, Roy van der Berg, Rob J. Timmermann, Ingrid Boerema, Iryna Mudruk, Anna Khrystoforova, Serhii Kyselov, Yaroslava V. Hilova, Pavlo Logoida, Nataliia A. Sanina, Ilona P. Golikova, Olena O. Nemchyna, Ivan I. Isaichikov, Olga B. Potapova, Iurii V. Gura, Larysa Berestetska, Olena O. Kulianda, Oleksandr Tantsura, Oleksandr S. Kulbachuk, Volodymyr Petsentiy, Ihor Biskub, Tetyana Handych, Oleg Lagkuti, Alyna Gagarina, Taras Chendey, Oksana F. Bilonko, Olena Matova, Larysa Bezrodna, Olena Yarynkina, Tetiana Ovdiienko, Volodymyr Randchenko, Maryna Mospan, Olena Butko, Olga Romanenko, Mykhailo Pavelko, Iryna Sichkaruk, Svitlana O. Lazareva, Olena A. Kudryk, Inessa M. Koltsun, Tetiana Magdalits, Sergei Zadorozhniy, Kira Kompaniiets, Andrii Ivanov, Sergiy Romanenko, Pavlo Kaplan, Vadym Y. Romanov, Oksana P. Mykytyuk, Nataliia S. Zaitseva, Sergiy N. Pyvovar, Lyudmyla Burdeuna, Emerita Serdobinska, Tatiana I. Shevchenko, Igor I. Ivanytskyi, Olena V. Khyzhnyak, Nataliya Kalinkina, Olena Keting, Olena Sklyanna, Olga Kashanska, Anna Shevelok, Marina Khristichenko, Ievgenii Y. Titov, Danilenko O. Oleksander, Nataliia S. Polenova, Nataliia Altunina, Viktoriia Kororaieva, Stanislav Zborovskiy, Leonid Kholopov, Iurii Suliman, Lanna Lukashenko, Stanislav Shvaykin, Olexandr M. Glavatskiy, Roman O. Sychov, Roman L. Kulynych, Oleksandr A. Skarzhevskyi, Nataliia V. Dovgan, Marta Horbach, Olga Cherkasova, Iryna Tyshchenko, Liudmyla Todoriuk, Svitlana Kizim, Nataliia Brodi, Oleksandr Ivanko, Olga Garbarchuk, Liudmyla Alieksieieva, Tetiana L. Shandra, Olena Beregova, Larisa An Bodretska, Svitlana S. Naskalova, Ivanna A. Antoniuk-Shcheglova, Olena V. Bondarenko, Natalia G. Andreeva, Iryna I. Vakalyuk, Olha S. Chovganyuk, Nataliya R. Artemenko, Kiril A. Maltsev, Natalia Kalishevich, Natalia G. Kondratyeva, Svetlana A. Nikitina, Maria V. Martjanova, Anna V. Sokolova, Dmitrii O. Dragunov, Olga Kolesnik, Vera Larina, Oxana V. Tsygankova, Maria Ivanova, Illia A. Karpov, Elena M. Aronova, Ekaterina S. Vedernikova, Ekaterina I. Lubinskaya, Taras Y. Burak, Sergey I. Skichko, Farhad Rasulev, Ekaterina B. Soldatova, Alexander L. Fenin, Ilya I. Laptev, Elena E. Luchinkina, Alexandr Akatov, Natalia V. Polenova, Natalia N. Slavina, Irina N. Korovnika, Marina Yu Prochorova, Regina Shakirova, Elena N. Andreicheva, Olga A. Krasnova, Tinatin V. Lobzhanidze, Tatiana B. Dmitrova, Viktoriya V. Stakhiv, Maria I. Pechatnikova, Alexandra V. Panova, Maria Y. Tipikina, Oxana P. Rotar, Nikolay A. Bokovin, Saule K. Karabalieva, Farid Y. Tumarov, Elena V. Vasileva, Natalya Gennadevna Lozhkina, Ekaterina V. Filippova, Alisa I. Sharkaeva, Ekanerina V. Filippova Deilik, Natalia Yu Tolkacheva, Elena N. Domracheva, Andrey N. Ryabikov, Inga T. Abesadze, Marianna Z. Alugishvili, Elena P. Nikolaeva, Nadezda V. Smirnova, Valentina I. Rodionova, Polina V. Dolovstaya, Igor E. Yunonin, Sergey V. Kadin, Tatyana S. Sveklina, Anna V. Bushmanova, Elena L. Barkova, Irina S. Gomova, Yana V. Brytkova, Tatiana B. Ivanova, Marina Y. Zubareva, Inga Skopets, Lybov A. Galashevskaya, Emilia D. Butinskaya, Olga G. Gusarova, Natalia B. Kalishevich, Yana R. Pavlova, Marianna P Serebrenitskaya, Vitalina F. Grygorieva, Gulnara R. Kuchaeva, Inna A. Vasileva, Gulnara I. Ospanova, Yulia V. Vahrusheva, Irina A. Semenova, Irina E.E. Mikhailova, Olga O. Kvasova, Valeria D. Shurygina, Alexey E. Rivin, Alexey O. Savelyev, Alexey A. Savelyev, Olesya O. Milyaeva, Nadezhda N. Lapshina, Ninel A. Lantsova, Pavel V. Alexandrov, Evgeniy A. Orlikov, Alla Falkovskaya, Tatiana Ripp, Sergei Triss, Stanislav Pekarskiy, Sitkova Ekaterina, Evgeniya N. Zhuravleva, Olga Perova, Galina Kovaleva, Liubov Koroleva, Lydia Mishchenko, Boris P. Garshin, Svetlana A. Kutuzova, Lyudmila I. Provotorova, Igor P. Zadvorny, Olga V. Okhapkina, Anatoly O. Khrustalev, Tatiana Suvorova, Elena S. Shaf, Varvara A. Vershinina, Andrey A. Kozulin, Oxana A. Oleynik, Irina Y. Martynova, Natalia V. Kizhvatova, Alla S. Salasyuk, Vera V. Tsoma, Alla A. Ledyaeva, Elena V. Chumachek, S.C. Blignaut, Tersia Y. Alexander, Chano Du Plessis, Thirumani Govender, Samatha M. Du Toit, Leya Motala, Areesh Gassiep, Christina Naude (Smit), Marli Terblanche, Marlien Snoer (Kruger), Berenice Pillay, De Vries Basson, Marisa E. Theron, Bianca Fouche, Mareli E. Coetzee, Pieter Odendall, Frederik H. Van Wijk, Anna-Mari Conradie, Trudie Van der Westhuizen, Carine Tredoux, Mohamed S. Mookdam, Andie J. Van der Merwe, Karin Snyman, Gerda Smal, Yvonne De Jager, Thomas A. Mabin, Annusca King, Lindy L. Henley, Brenda M. Zwane, Jane Robinson, Marinda Karsten, Andonia M. Page, Valerie Nsabiyumva, Charmaine Krahenbuhl, Jaiprakash D. Patel, Yunus E. Motala, Ayesha Dawood, Nondumiso B. Koza, Lenore M.S. Peters, Shavashni Ramlachan, Wilhelm J. Bodenstein, Pierre Roux, Lizelle Fouche, Cecilia M. Boshoff, Haroon M. Mitha, Fathima Khan, Henry P. Cyster, Helen Cyster, E. C. Wessels, Florence J. Jacobs, Melanie A. Sebastian, Deborah A. Sebastian, Nadia Mahomed, Ignatius P. Immink, Celia Cotzee, Tanja Cronje, Madele Roscher, Maria Le Roux, Yvonne A. Trinder, Renata Wnętrzak-Michalska, Magdalena Piszczek, Andrzej Piela, Ewa Czernecka, Dorota Knychas, Alina Walczak, Izabella Gładysz, Katarzyna Filas, Ewelina Kiluk, Krzysztof Świgło, Iwona Jędrzejczyk, Kamila Łuczyńska, Katarzyna Tymendorf, Wojciech Piesiewicz, Wojciech L. Kinasz, Stefan Samborski, Ilona Bartuś, Gramzyna Latocha Korecka, Ewa Gulaj, Jolanta Sopa, Bogusław Derlaga, Marcin Baisiak, Allicia Kowalisko, Edyta Stainszewska-Marasazlek, Bartosz Szafran, Malgorzata Swiatkiewicz, Artur Racewicz, Sławomir Grycel, Jerzy Supronik, Sylwia Walendziuk, Magdalena Tarantowicz, Agata Stasiak, Anna Sidorowicz-Białynicka, Marek Dwojak, Ewa Jaźwińska-Tarnawska, Katarzyna Kupczyk, Kamila Martowska, Kamila Kulon, Katarzyna Gajda, Bivin Wilson, Krithika Velusamy, Swaidha S. Sadhiq, Bhavani Siddeshi, M. Bhanukumar, Abhishek Srivatsav, Madhan Ramesh, Sri Harsha Chalasani, Mini Johnson, Prashanth Gopu, Jeesa George, Sowmya Reddy, Swetha Tessy Thara Eleena, Damodara Rao Kodem, Haritha N. Nakkella, Padma Kumari Mandula, Anjan Kumar Vuriya, Syamala Rajana, Aruna Kale, Tiwari Rajeev, Raina Jain, Vipin Jain, Srilakshmi Mandayam Adhyapak, Lumin Sheeba, Uma C R, Ramya R, Aditya V. Kulkarni, M.S. Ganachari, Ruma Sambrekar, Mohammad Bilal, Kalyan Chakravarthy, Ravi Badhavath, Sravan Kumar, Meenakshi Simhadri, Farooque Salamuddin, Venkat Prasad, Vivek Dwivedi, Sudha Sarna, Tilak Arora, Deepak Chawla, Archana Sathe, Chaware Gayatree, Ajeet Nanda, Ram Avtar, Jyoti Sharma, Vaibhavi P S, Sasirekha D, Deepthi Kobbajji, Ramya Ningappa, Shwetha Shree, Chandrashekar K, Nandini M R, Sowjanya S, Devika I G, Yashaswini N, Sonika G, Rathna L, Priyanka R, Rupal J. Shrimanker, Lakshmi Vinutha Reddy, K. Sumathi, Babitha Devi, Bina N. Naik, Rohini Manjunath, Rajeshwari Ashok, Tony V. Kunjumon, Jesline Thomas, Shaik Samdhani, Kasthuri Selvam, Poongothai Subramani, Nandakumar Parthasarathy, Nirmal K. Bohra, Anvesh K. Gatla, Cheryl Horbatuk, Julie Sills, E B. Davey, Liz Paramonczyk, Olga Racanelli, Sandy Strybosch, Andre Belanger, Jean Palardy, Alicia Schiffrin, Sylvie Gauthier, Norman Kalyniuk, Shawn D. Whatley, Heather Lappala, Grishma Patel, Matthew Reeve, Catherine Moran, Jody Everitt, Teresa Ferrari, Christine Bouffard, Jirir Frohlich, Gordon Francis, John Mancini, Gregory Bondy, Debbie DeAngelis, Patricia Fulton, David W. Blank, Angela Lombardo, Mylène Roy, Jackie Chow, Hyman Fox, William J. Grootendorst, Angela Hutchinson, Sharon M. Chan, Christie Fitzgerald, Lynn Wilkins, Rebecca L. Raymond, Arlene Reyes, Lavoie Marc André, Denis Fortin, Hélène Ouimet, Thanh-Thao Tôn-Nu, Martine Dussureault, Marie-Hélène Blain, Madeleine Roy, Nathalie Kopajko, Chantal Fleury, Karine Maheux, Gabriela Valentina Ciobotaru, Maria C. Constantinescu, Carmen-Lucia Gherghinescu, Ana-Maria Avram, Ioan Manitiu, Aura Sinpetrean, Lucian Pop, Delia Lupu, Radu Usvat, Ana Petrisor, Nicoleta Dumitru, Camelia Moruju, Adelina Gheorghita, Magda V. Mitu, Cosmin Macarie, Ana Maria Pop, Maria-Catalina Diaconu, Iulia Grancea, Mihaela Cosma, Mihaela Crisan, Elizabeth Herron, Paul Nestel, Sally B. Kay, Kaye S. Carter, Imran Badshah, Ashley Makepeace, Jocelyn Drinkwater, Michelle England, Azette Rafei, Kylie Patterson, Alicia Jenkins, Sybil McAuley, Sue M. Kent, Joy E. Vibert, Leonie Perrett, Thomas David, Samantha L. Kaye, Monika O’Connor, Nimalie J. Perera, Nicole T. Lai, Kerry A. Kearins, Christinia Dicamillo, Heather Anderson, Louise Ferguson, Sharon D. Radtke, Charles T. Thamarappillil, Janice M. Boys, Anita K. Long, Toni Shanahan, Michael Nyguyen, Nicole Forrest, Gill Tulloch, Della Greenwell, Sarah L. Price, Aye N. Tint, Priya K. Sumithran, Tamara L. Debreceni, Lisa Walker, Mary Caruana, Kira Edwards, Maria Stathopoulos, Cilla Haywood, Dimitar Sajkov, Sharen Pringle, Anne Tabner, Kathrina Bartolay, Chamindi Abeyratne, Kylie Bragg, Patrick Mulhern, Peter Purnell, Lyn Williams, Jane Hamlyn, Aurelia Connelly, Jan Hoffman, Samantha Bailey, Jane Kerr, Zarnia Morrison, Sarah Maeder, Roberta McEwan, Prasanna Kunasekera, Patrice McGregor, Jo Young, Sharon Berry, Rick Cutfield, Michelle Choe, Catherine McNamara, Narrinder K. Shergill, Petra Crone, Miles G. Williams, Keith Dyson, Diana H. Schmid, Audrey C. Doak, Melissa Spooner, Colin Edwards, Anne Turner, Grainne M. McAnnalley, Raewyn A. Fisher, Fraser B. Hamilton, Denis H. Friedlander, Melissa R. Kirk, Jayne E. Scales, Marguerite A. McLelland, Neelam A. Dalman, Cathy E. Vickers, Carolyn Jackson, Wendy Coleman, Phillip I. Garden, and Wendy F. Arnold
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Male ,medicine.medical_specialty ,Rate ratio ,Double-Blind Method ,Ischemia ,Risk Factors ,Physiology (medical) ,Internal medicine ,medicine ,Clinical endpoint ,Humans ,Myocardial infarction ,Coronary Artery Bypass ,Stroke ,Aged ,business.industry ,Unstable angina ,Hazard ratio ,Absolute risk reduction ,Middle Aged ,medicine.disease ,Eicosapentaenoic Acid ,Number needed to treat ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: Despite advances in surgery and pharmacotherapy, there remains significant residual ischemic risk after coronary artery bypass grafting surgery. Methods: In REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl–Intervention Trial), a multicenter, placebo-controlled, double-blind trial, statin-treated patients with controlled low-density lipoprotein cholesterol and mild to moderate hypertriglyceridemia were randomized to 4 g daily of icosapent ethyl or placebo. They experienced a 25% reduction in risk of a primary efficacy end point (composite of cardiovascular death, myocardial infarction, stroke, coronary revascularization, or hospitalization for unstable angina) and a 26% reduction in risk of a key secondary efficacy end point (composite of cardiovascular death, myocardial infarction, or stroke) when compared with placebo. The current analysis reports on the subgroup of patients from the trial with a history of coronary artery bypass grafting. Results: Of the 8179 patients randomized in REDUCE-IT, a total of 1837 (22.5%) had a history of coronary artery bypass grafting, with 897 patients randomized to icosapent ethyl and 940 to placebo. Baseline characteristics were similar between treatment groups. Randomization to icosapent ethyl was associated with a significant reduction in the primary end point (hazard ratio [HR], 0.76 [95% CI, 0.63–0.92]; P =0.004), in the key secondary end point (HR, 0.69 [95% CI, 0.56–0.87]; P =0.001), and in total (first plus subsequent or recurrent) ischemic events (rate ratio, 0.64 [95% CI, 0.50–0.81]; P =0.0002) compared with placebo. This yielded an absolute risk reduction of 6.2% (95% CI, 2.3%–10.2%) in first events, with a number needed to treat of 16 (95% CI, 10–44) during a median follow-up time of 4.8 years. Safety findings were similar to the overall study: beyond an increased rate of atrial fibrillation/flutter requiring hospitalization for at least 24 hours (5.0% vs 3.1%; P =0.03) and a nonsignificant increase in bleeding, occurrences of adverse events were comparable between groups. Conclusions: In REDUCE-IT patients with a history of coronary artery bypass grafting, treatment with icosapent ethyl was associated with significant reductions in first and recurrent ischemic events. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT01492361.
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- 2021
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3. Access and communication for deaf individuals in Australian primary care
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Mark Harris, Phoebe H Lee, and Catherine Spooner
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Medicine (General) ,National Disability Insurance Scheme ,Psychological intervention ,Allied Health Personnel ,interpreters ,computer.software_genre ,Fluency ,equity ,access ,R5-920 ,Health care ,otorhinolaryngologic diseases ,Humans ,Social media ,Disabled Persons ,Medical education ,business.industry ,Communication ,Communication Barriers ,Public Health, Environmental and Occupational Health ,Australia ,Flexibility (personality) ,Original Articles ,primary health care ,Australian Sign Language (Auslan) ,Original Article ,Deaf Community ,Public aspects of medicine ,RA1-1270 ,business ,Psychology ,Accommodation ,computer ,Interpreter - Abstract
Background and aims The Australian Deaf Community face barriers that impede their access to, and communication within, primary health care settings. This study aimed to identify barriers and facilitators to access and communication for deaf individuals and Auslan interpreters in Australian general practice settings. Methods Semi-structured interviews were conducted with eight Auslan interpreters and four deaf participants recruited from interpreter organisations and social media. Transcripts of interviews were coded inductively and deductively based on a model of access to health care. Results Patient, provider and contextual factors were reported. Patient barriers included English and Auslan fluency levels within the Australian Deaf Community. GP clinics varied in the degree of accommodation to the needs of deaf people. There were barriers related to the communication methods used by health care providers and their use of interpreters. Visual aids and flexibility in terms of the GP clinics' appointment systems facilitated access. Contextual barriers included the shortage of Auslan interpreters and the complexity of the National Disability Insurance Scheme. Conclusion The main barriers identified concerned the availability of interpreters, accommodation by health providers, cultural sensitivity and the adequacy of communication methods. Research is needed to explore the limitations of the National Disability Insurance Scheme and interventions to improve GPs' skills in communicating with Deaf individuals. Patient or public contribution A researcher with a hearing impairment and experience in working with people with hearing impairments was consulted on study design and interview questions. Recruitment was assisted by Auslan interpreter agencies and a Deaf Community Facebook group.
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- 2021
4. Obesity and HIV: a compounding problem
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Elizabeth Spooner and Chara Biggs
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0301 basic medicine ,medicine.medical_specialty ,Nutrition and Dietetics ,biology ,business.industry ,C-reactive protein ,Human immunodeficiency virus (HIV) ,Serum albumin ,Albumin ,Medicine (miscellaneous) ,medicine.disease_cause ,medicine.disease ,030112 virology ,Obesity ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Compounding ,Internal medicine ,medicine ,biology.protein ,HIV ,ART-naïve ,obesity ,albumin ,030212 general & internal medicine ,business - Abstract
Objectives: A cross-sectional study was undertaken at Lancers Road Clinic, Durban, South Africa to determine body composition, haemoglobin, serum albumin and serum high sensitivity C-reactive protein (hs-CRP) levels in asymptomatic ART-naive HIV positive adults. Methods: All eligible adults attending the clinic were sampled. Body composition was assessed using deuterium dilution. Descriptive statistics, Wilcoxon rank-sum test, chi-square test, Fisher’s exact test and Spearman’s rank correlation coefficient were used for data analysis. Results: A total of 84 participants (CD4 count: 542.5 ± 145 cell/mm3) enrolled. The mean body mass index (BMI) was 29.5 (± 6.4) kg/m2 and the mean fat mass percentage was 44.9 (± 18.7). The prevalence of overweight (26.2%, 22/84) and obesity (46.4%, 39/84) was high. Mean haemoglobin (Hb) levels were 12.0 ± 1.6 g/dl. Mild, moderate and severe anaemia was present in 21.4% (18/84), 20.2% (17/84) and 1.2% (1/84) of patients, respectively. Mean albumin levels (36.2 ± 3.8 g/l) were on the borderline low range of normal with mildly depleted albumin levels being present in a third (32.1%, 27/84) of patients. The mean hs-CRP levels (5.5 ± 7.2 mg/l) were high. Conclusion: In this cohort of patients, wasting was not associated with HIV as the prevalence of overweight/obesity was high and followed the population trend in SA. This seemingly well, asymptomatic population of people living with HIV was at an increased risk of morbidity, progression and death due to the compounding factors of overweight/obesity, hypoalbuminemia, raised hs-CRP levels and anaemia.
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- 2023
5. Initial Invasive or Conservative Strategy for Stable Coronary Disease
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Maron D. J., Hochman J. S., Reynolds H. R., Bangalore S., O'Brien S. M., Boden W. E., Chaitman B. R., Senior R., Lopez-Sendon J., Alexander K. P., Lopes R. D., Shaw L. J., Berger J. S., Newman J. D., Sidhu M. S., Goodman S. G., Ruzyllo W., Gosselin G., Maggioni A. P., White H. D., Bhargava B., Min J. K., John Mancini G. B., Berman D. S., Picard M. H., Kwong R. Y., Ali Z. A., Mark D. B., Spertus J. A., Krishnan M. N., Elghamaz A., Moorthy N., Hueb W. A., Demkow M., Mavromatis K., Bockeria O., Peteiro J., Miller T. D., Szwed H., Doerr R., Keltai M., Selvanayagam J. B., Gabriel Steg P., Held C., Kohsaka S., Mavromichalis S., Kirby R., Jeffries N. O., Harrell F. E., Rockhold F. W., Broderick S., Bruce Ferguson T., Williams D. O., Harrington R. A., Stone G. W., Rosenberg Y, ISCHEMIA Research Group: Joseph Ricci, A Tello Montoliu, A I Robero Aniorte, Abbey Mulder, Abhay A Laddu, Abhinav Goyal, Abhishek Dubey, Abhishek Goyal, Abigail Knighton, Abraham Oomman, Adam J Jaskowiak, Adam Kolodziej, Adam Witkowski, Adnan Hameed, Adriana Anesini, Afshan Hussain, Agne Juceviciene, Agne Urboniene, Agnes Jakal, Agnieszka Szramowska, Ahmad Khairuddin, Ahmed Abdel-Latif, Ahmed Adel, Ahmed Aljzeeri, Ahmed Kamal, Ahmed Talaat, Aimee Mann, Aira Contreras, Ajit Kumar, V K Kumar, Akemi Furukawa, Akshay Bagai, Akvile Smigelskaite, Alain Furber, Alain Rheault, Alaine Melanie Loehr, Alan Rosen, Albert Varga, Albertina Qelaj, Alberto Barioli, Aldo Russo, Alec Moorman, Alejandro Gisbert, Aleksandra Fratczak, Aleksandras Laucevicius, Alena Kuleshova, Alessandro Sionis, Alexander A Sirker, Alexander M Chernyavskiy, Alexandra Craft, Alexandra Vazquez, Alexandre Ciappina Hueb, Alexandre S Colafranseschi, Alexandre Schaan de Quadros, Alexandre Tognon, Ali Alghamdi, Alice Manica Muller, Aline Nogueira Rabaça, Aline Peixoto Deiro, Alison Hallam, Allegra Stone, Allison Schley, Almudena Castro, Alvaro Rabelo Ales, Amanda Germann, Amanda O'Malley, Amar Uxa, Amarachi Ojajuni, Amarino C Oliveira Jr, Amber B Hull, Ambuj Roy, Amer Zarka, Amir Janmohamed, Ammani Brown, Ammy Malinay, Amparo Martinez Monzonis, Amy J Richards, Amy Iskandrian, Amy Ollinger, Ana D Djordjevic-Dikic, Ana Fernández Martínez, Ana Gomes Almeida, Ana Paula Batista, Ana Rita Francisco, Ana S Mladenovic, Ana Santana, Anam Siddiqui, Anastasia M Kuzmina-Krutetskaya, Andras Vertes, Andre S Sousa, Andre Gabriel, André Schmidt, Andrea M Lundeen, Andrea Bartykowszki, Andrea Lorimer, Andrea Mortara, Andrea Pascual, Andreia Coelho, Andreia Rocha, Andrés García-Rincón, Andrew G Howarth, Andrew J Moriarty, Andrew Docherty, Andrew Starovoytov, Andrew Zurick, Andrzej Łabyk, Andrzej Swiatkowski, Andy Lam, Anelise Kawakami, Angela Hoye, Angela Kim, Angelique Smit, Angelo Nobre, Anil V Shah, Anja Ljubez, Anjali Anand, Ankush Sachdeva, Ann Greenberg, Ann Luyten, Ann Ostrander, Anna Di Donato, Anna Cichocka-Radwan, Anna Fojt, Anna Plachcinska, Anna Proietti, Anna Teresinska, Anne Marie Webb, Anne Cartwright, Anne Heath, Anne Mackin, Anong Amaritakomol, Anong Chaiyasri, Anoop Chauhan, Anoop Mathew, Anthony Gemignani, Anto Luigi Andres, Antonia Vega, Antonietta Hansen, Antonino Ginel Iglesias, Antonio Carlos Carvalho, Antonio Di Chiara, Antonio Serra Peñaranda, Antonio Carvalho, Antonio Colombo, Antonio Fiarresga, Anupama Rao, Aquiles Valdespino-Estrada, Araceli Boan, Areef Ishani, Ariel Diaz, Arijit Ghosh, Arintaya Prommintikul, Arline Roberts, Arnold H Seto, Arnold P Good, Arshed Quyyumi, Arthur J Labovitz, Arthur Kerner, Arturo S Campos-Santaolalla, Arunima Misra, Ashok Mukherjee, Ashok Seth, Ashraf Seedhom, Asim N Cheema, Asker Ahmed, Atul Mathur, Atul Verma, Audrey W Leong, Axel Åkerblom, Axelle Fuentes, Aynun Naher, Badhma Valaiyapathi, Baljeet Kaur, Bandula Guruge, Barbara Brzezińska, Barbara Nardi, Bartosz Czarniak, Bebek Singh, Begoña Igual, Bela Merkely, Belen Cid Alvarez, Benjamin J Spooner, Benjamin J W Chow, Benjamin Cheong, Benoy N Shah, Bernard de Bruyne, Bernardas Valecka, Bernhard Jäger, Beth A Archer, Beth Abramson, Beth Jorgenson, Bethany Harvey, Betsy O'Neal, Bev Atkinson, Bev Bozek, Bevin Lang, Bijulal Sasidharan, Bin Yang, Bin Zhang, Binoy Mannekkattukudy Kurian, Bjoern Goebel, Bob Hu, Bogdan A Popescu, Bogdan Crnokrak, Bolin Zhu, Bonnie J Kirby, Brandi D Zimbelman, Brandy Starks, Branko D Beleslin, Brenda Hart, Brian P Shapiro, Brian McCandless, Brianna Wisniewski, Brigham R Smith, Brooks Mirrer, Bruce McManus, Bruce Rutkin, Bruna Edilena Paulino, Bruna Maria Ascoli, Bryn Smith, Byron J Allen, C Michael Gibson, C Noel Bairey Merz, Calin Pop, Cameron Hague, Camila Thais de Ormundo, Candace Gopaul, Candice P Edillo, Carísi A Polanczyk, Carita Krannila, Carla Vicente, Carl-Éric Gagné, Carlo Briguori, Carlos Peña Gil, Carlos Alvarez, Carly Ohmart, Carmen C Beladan, Carmen Ginghina, Carol M Kartje, Caroline Alsweiler, Caroline Brown, Caroline Callison, Caroline Pinheiro, Caroline Rodgers, Caroline Spindler, Carolyn Corbett, Carrie Drum, Casey Riedberger, Catherine Bone, Catherine Fleming, Catherine Gordon, Catherine Jahrsdorfer, Catherine Lemay, Catherine Weick, Cathrine Patten, Cecilia Goletto, Cezary Kepka, Chandini Suvarna, Chang Xu, Chantale Mercure, Charle A Viljoen, Charlene Wiyarand, Charles Jia-Yin Hou, Charles Y Lui, Charles Cannan, Charles Cornet, Charlotte Pirro, Chataroon Rimsukcharoenchai, Chen Wang, Cheng-Ting Tsai, Chen-Yen Chien, Cheryl A Allardyce, Chester M Hedgepeth, Chetan Patel, Chiara Attanasio, Chih-Hsuan Yen, Chi-Ming Chow, Ching Min Er, Ching-Ching Ong, Cholenahally Nanjappa Manjunath, Chris Beck, Chris Buller, Christel Vassaliere, Christian Hamm, Christiano Caldeira, Christie Ballantyne, Christina Björklund, Christine R Hinton, Christine Bergeron, Christine Masson, Christine Roraff, Christine Shelley, Christophe Laure, Christophe Thuaire, Christopher Kinsey, Christopher McFarren, Christopher Spizzieri, Christopher Travill, Chun-Chieh Liu, Chung-Lieh Hung, Chunguang Li, Chun-Ho Yun, Chunli Xia, Ciarra Heard, Cidney Schultz, Clare Venn-Edmonds, Claudia P Hochberg, Claudia Wegmayr, Claudia Cortés, Claudia Escobar, Cláudia Freixo, Claudio T Mesquita, Clemens T Kadalie, Colin Berry, Constance Philander, Corine Thobois, Costantino Costantini, Courtney Page, Craig Atkinson, Craig Barr, Craig Paterson, Cristina Bare, Cynthia Baumann, Cynthia Burman, Dalisa Espinosa, Damien Collison, Dan Deleanu, Dan Elian, Dan Gao, Dana Oliver, Daniel P Vezina, Daniel O'Rourke, Daniele Komar, Danielle Schade, Darrel P Francis, Dastan Malaev, David A Bull, David E Winchester, David P Faxon, David Booth, David Cohen, David DeMets, David Foo, David Schlichting, David Taggart, David Waters, David Wohns, Davis Vo, Dawid Teodorczyk, Dawn Shelstad, Dawn Turnbull, Dayuan Li, Dean Kereiakes, Deborah O'Neill, Deborah Yip, Debra K Johnson, Debra Dees, Deepak L Bhatt, Deepika Gopal, Deepti Kumar, Deirdre Mattina, Deirdre Murphy, Delano R Small, Delsa K Rose, Dengke Jiang, Denis Carl Phaneuf, Denise Braganza, Denise Fine, Derek Cyr, Desiree Tobin, Diana Cukali, Diana Parra, Diane Camara, Diane Minshall Liu, Diego Adrián Vences, Diego Franca de Cunha, Dimitrios Stournaras, Dipti Patel, Dongze Li, Donna Exley, Dorit Grahl, Dragana Stanojevic, Duarte Cacela, Dwayne S G Conway, E Pinar Bermudez, Eapen Punnoose, Edgar L Tay, Edgar Karanjah, Edoardo Verna, Eduardo Hernandez-Rangel, Edward D Nicol, Edward O McFalls, Edward T Martin, Edyta Kaczmarska, Ekaterina I Lubinskaya, Elena A Demchenko, Elena Refoyo Salicio, Eli Feen, Elihú Durán-Cortés, Elisabeth M Janzen, Elise L Hannemann, Elise van Dongen, Elissa Restelli Piloto, Eliza Kaplan, Elizabeta Srbinovska Kostovska, Elizabeth Capasso-Gulve, Elizabeth Congdon, Elizabeth Ferguson, Elizaveta V Zbyshevskaya, Ellen Magedanz, Ellie Fridell, Ellis W Lader, Elvin Kedhi, Emanuela Racca, Emilie Tachot, Emily DeRosa, Encarnación Alonso-Álvarez, Eric Nicollet, Eric Peterson, Erick Alexánderson Rosas, Erick Donato Morales, Erin Orvis, Ermina Moga, Estelle Montpetit, Estevao Figueiredo, Eugene Passamani, Eugenia Nikolsky, Eunice Yeoh, Evgeniy I Kretov, Ewa Szczerba, Ewelina Wojtala, Expedito Eustáquio Ribeiro Silva, F Marin Ortuño, Fabio R Farias, Fabio Fimiani, Fabrizio Rolfo, Fa-Chang Yu, Fadi Hage, Fadi Matar, Fahim Haider Jafary, Fang Feng, Fang Liu, Fatima Ranjbaran, Fatima Rodriguez, Fausto J Pinto, Fauzia Rashid, Federica Ramani, Fei Wang, Fernanda Igansi, Filipa Silva, Filippo Ottani, Fiona Haines, Firas Al Solaiman, Flávia Egydio, Flavio Lyra, Florian Egger, Fran Farquharson, Frances Laube, Francesc Carreras Costa, Francesca de Micco, Francesca Bianchini, Francesca Pezzetta, Francesca Pietrucci, Francesco Orso, Francesco Pisano, Francis Burt, Francisca Patuleia Figueiras, Francisco Fernandez-Aviles, Francois Pierre Mongeon, Frans Van de Werf, Franziska Guenther, Fraser N Witherow, Fred Mohr, Frederico Dall'Orto, Fumiyuki Otsuka, G De La Morena, G Karthikeyan, Gabor Dekany, Gabor Kerecsen, Gabriel Galeote, Gabriel Grossmann, Gabriel Vorobiof, Gabriela Sanchez de Souza, Gabriela Guzman, Gabriela Zeballos, Gabriele Gabrielli, Gabriele Jakl-Kotauschek, Gail A Shammas, Gail Brandt, Gang Chen, Gary E Lane, Gary J Luckasen, Gautam Sharma, Gelmina Mikolaitiene, Gennie Yee, Georg Nickenig, George E Revtyak, George J Juang, Gerald Fletcher, Gerald Leonard, Gerard Patrick Devlin, Gerard Esposito, Gergely Ágoston, Gervasio Lamas, Geza Fontos, Ghada Mikhail, Gia Cobb, Gian Piero Perna, Gianpiero Leone, Giles Roditi, Gilles Barone-Rochette, Girish Mishra, Giuseppe Tarantini, Glenda Wong, Glenn S Hamroff, Glenn Rayos, Gong Cheng, Gonzalo Barge-Caballero, Goran Davidović, Goran Stankovic, Gordana Stevanovic, Grace Jingyan Wang, Grace M Young, Graceanne Wayser, Graciela Scaro, Graham S Hillis, Graham Wong, Grazyna Anna Szulczyk, Gregor Simonis, Gregory Kumkumian, Gretchen Ann Peichel, Grzegorz Gajos, Gudrun Steinmaurer, Guilherme G Rucatti, Guilherme Portugal, Guilhermina Cantinho Lopes, Guillem Pons Lladó, Gunnar Frostfelt, Gurpreet S Wander, Gurpreet Gulati, Gustavo Pucci, Hafidz Abd Hadi, Haibo Zhang, Haitao Wang, Halina Marciniak, Han Chen, Hanan Kerr, Hani Najm, Hanna Douglas, Hannah Phillips, Hao Dai, Haojian Dong, Haqeel Jamil, Harikrishnan Sivadasanpillai, Harry Suryapranata, Hassan Reda, Hayley Pomeroy, Heather Barrentine, Heather Golden, Heather Hurlburt, Heidi Wilson, Helen C Tucker, Helene Abergel, Hemalata Siddaram, Hermine Osseni, Herwig Schuchlenz, Hesong Zeng, Hicham Skali, Hilda Solomon, Hollie Horton, Holly Hetrick, Holly Little, Holly Park, Hongjie Chi, Hossam Mahrous, Howard A Levite, Hristo Pejkov, Huajun Li, Hugo Bloise-Adames, Hugo Marques, Hui Zhong, Hui-Min Zhang, Humayrah Hashim, Hung-I Yeh, Hussien El Fishawy, Ian Webb, Iftikhar Kullo, Igor O Grazhdankin, Ihab Hamzeh, Ikraam Hassan, Ikuko Ueda, Ileana L Pina, Ilona Tamasauskiene, Ilse Bouwhuis, Imran Arif, Ina Wenzelburger, Inês Zimbarra Cabrita, Ines Rodrigues, Inga H Robbins, Inga Soveri, Ingela Schnittger, Iqbal Karimullah, Ira M Dauber, Iram Rehman, Irena Peovska Mitevska, Irene Marthe Lang, Irina Subbotina, Irma Kalibataite-Rutkauskiene, Irni Yusnida, Isabel Estela Carvajal, Isabella C Palazzo, Isabelle Hogan, Isabelle Roy, Ishba Syed, Ishita Tejani, Ivan A Naryshkin, Ivana Jankovic, Iwona Niedzwiecka, J David Knight, Jacek Kusmierek, Jackie M White, Jackie Chow, Jacob Udell, Jacqueline E Tamis-Holland, Jacqueline Fannon, Jacquelyn A Quin, Jacquelyn Do, Jaekyeong Heo, Jakub Maksym, James E Davies, James H O'Keefe Jr, James J Jang, James Cha, James Harrison, James Hirsch, James Stafford, James Tatoulis, Jamie Rankin, Jan Henzel, Jan Orga, Jana Tancredi, Janaina Oliveira, Jane Burton, Jane Eckstein, Jane Marucci, Janet P Knight, Janet Blount, Janet Halliday, Janetta Kourzenkova, Janitha Raj, Jan-Malte Sinning, Jaqueline Pozzibon, Jaroslaw Drozdz, Jaroslaw Karwowski, Jason D Glover, Jason Loh Kwok, Jason T Call, Jason Linefsky, Jassira Gomes, Jati Anumpa, Javier J Garcia, Javier Courtis, Jay Meisner, K Jayakumar, Jayne Scales, Jean E Denaro, Jean Michel Juliard, Jean Ho, Jeanette K Stansborough, Jean-Michel Juliard, Jeanne Russo, Jeannette J M Schoep, Jeet Thambyrajah, Jeff Leimberger, Jeffery A Breall, Jeffrey A Kohn, Jeffrey C Milliken, Jeffrey Anderson, Jeffrey Blume, Jeffrey Kanters, Jeffrey Lorin, Jeffrey Moses, Jelena J Stepanovic, Jelena Celutkiene, Jelena Djokic, Jelena Stojkovic, Jenne M Jose, Jenne Manchery, Jennifer A Mull, Jennifer H Czerniak, Jennifer L Stanford, Jennifer Gillis, Jennifer Horst, Jennifer Isaacs, Jennifer Langdon, Jennifer Thomson, Jennifer Tomfohr, Jennifer White, Jen-Yuan Kuo, Jeremy Rautureau, Jerome Fleg, Jessica Berg, Jessica Rodriguez, Jessica Waldron, Jhina Patro, Jia Li, Jiajia Mao, Jiamin Liu, Jian'an Wang, Jianhua Li, Jianxin Zhang, Jie Qi, Jihyun Lyo, Jill Marcus, Jim Blankenship, Jing Zhang, Jingjing Liu, Jing-Yao Fan, Jiun-Yi Li, Jiwan Pradhan, Jiyan Chen, J M Rivera Caravaca, Jo Evans, Joan Garcia Picart, Joan Hecht, Joanna Jaroch, Joanna Zalewska, Joanne Kelly, Joanne Taaffe, João Reynaldo Abbud, João V Vitola, Joaquín V Peñafiel, Jocelyne Benatar, Jody Bindeman, Joe Sabik, Joel Klitch, Johann Christopher, Johannes Aspberg, John D Friedman, John F Beltrame, John F Heitner, John Joseph Graham, John R Davies, John Doan, John Kotter, John Kurian, John Mukai, John Pownall, Jolanta Sobolewska, Jon Kobashigawa, Jonathan L Goldberg, Jonathan W Bazeley, Jonathan Byrne, Jonathan Himmelfarb, Jonathan Leipsic, Jonean Thorsen, Jorge F Trejo Gutierrez, Jorge Escobedo, Jorik Timmer, José A Ortega-Ramírez, José Antonio Marin-Neto, Jose D Salas, Jose Enrique Castillo, Jose Francisco Saraiva, José J Cuenca-Castillo, Jose L Diez, José Luis Narro Villanueva, José Luiz da Vieira, José M Flores-Palacios, Jose Ramon Gonzalez, Jose Seijas Amigo, Jose Fragata, Josep Maria Padró, Josheph F X McGarvey Jr, Joseph Hannan, Joseph Sacco, Joseph Sweeny, Joseph Wiesel, Josephine D Abraham, Joshua P Loh, Joy Burkhardt, Joyce R White, Joyce Riestenberg-Smith, Judit Sebo, Judith L Meadows, Judith Wright, Judy Mae Foltz, Judy Hung, Judy Otis, Juergen Stumpf, Jui-Peng Tsai, Julia S Dionne, Julia de Aveiro Morata, Julie Bunke, Julie Morrow, Julio César Figal, Jun Fujita, Jun Jiang, Junhua Li, Junqing Yang, Juntima Euathrongchit, Jyotsna Garg, K Manjula Rani, K Preethi, Kaatje Goetschalckx, Kai Eggers, Kamalakar Surineni, Kanae Hirase, T R Kapilamoorthy, Karen Calfas, Karen Gratrix, Karen Hallett, Karen Hultberg, Karen Nugent, Karen Petrosyan, Karen Swan, Karolina Kryczka, Karolina Wojtczak-Soska, Karolina Wojtera, Karsten Lenk, Karthik Ramasamy, Katarzyna Łuczak, Katarzyna Malinowska, Kate Pointon, Kate Robb, Katherine Martin, Kathleen Claes, Kathryn Carruthers, Kathy E Siegel, Katia Drouin, Katie Fowler-Lehman, Kavita Rawat, Kay Rowe, Keiichi Fukuda, Keith A A Fox, Ken Mahaffey, Kendra Unterbrink, Kenneth Giedd, Kerrie Van Loo, Kerry Lee, Kerstin Bonin, Kevin R Bainey, Kevin T Harley, Kevin Anstrom, Kevin Chan, Kevin Croce, Kevin Landolfo, Kevin Marzo, Keyur Patel, Khaled Abdul-Nour, Khaled Alfakih, Khaled Dajani, Khaled Ziada, Khaula Baloch, Khrystyna Kushniriuk, Kian-Keong Poh, Kim F Ireland, Kim Holland, Kimberly Ann Byrne, Kimberly E Halverson, Kimberly Elmore, Kimberly Miller-Cox, Kiran Reddy, Kirsten J Quiles, Kirsty Abercrombie, Klaus Matschke, Konrad Szymczyk, Koo Hui Chan, Kotiboinna Preethi, Kozhaya Sokhon, Krissada Meemuk, Kristian Thygesen, Kristin M Salmi, Kristin Newby, Kristina Wippler, Kristine Arges, Kristine Teoh, Krystal Etherington, Krystyna Łoboz-Grudzień, Krzysztof W Reczuch, Krzysztof Bury, Krzysztof Drzymalski, Krzysztof Kukuła, Kuo-Tzu Sung, Kurt Huber, Ladda Douangvila, Lance Sullenberger, Larissa Miranda Trama, Laszlone Matics, Laura Drew, Laura Flint, Laura Keinaite, Laura Sarti, Laurel Kolakaluri, Lawrence M Phillips, Lawrence Friedman, Lawrence Phillips, Lazar Velicki, Leah Howell, Leandro C Maranan, Leanne Cox, Ledjalem Daba, Lei Zhang, Lekshmi Dharmarajan, Leo Bockeria, Leonardo Pizzol Caetano, Leonardo Bridi, Leonid L Bershtein, Leszek Sokalski, Li Hai Yan, Li Li, Lia Nijmeijer, Lidia Sousa, Lihong Xu, Lihua Zhang, Lili Zhang, Lilia Schiavi, Lilian Mazza Barbosa, Lillian L Khor, Lina Felix-Stern, Linda L Hall, Linda M Hollenweger, Linda Arcand, Linda Davidson-Ray, Linda Schwarz, Lindsey N Sikora, Lingping Chi, Lino Patricio, Liping Zhang, Lisa Chaytor, Lisa Hatch, Lisa McCloy, Lisa Wong, Liselotte Persson, Lixin Jiang, Liz Low, Ljiljana Pupic, Loïc Bière, Lorenzo Monti, Lori Christensen, Lori Pritchard, Loriane Black, Lori-Ann Desimone, Lori-Ann Larmand, Lorraine McGregor, Louise Morby, Louise Thomson, Luc Harvey, Luciana de Pádua Baptista, Lucilla Garcia, Ludivine Eliahou, Ludmila Helmer, Luis F Smidt, Luis Bernanrdes, Luis Guzman, Luiz A Carvalho, Luyang Xiong, Lynette L Teo, Lynn M Neeson, Lynne Winstanley, M Barbara Srichai-Parsia, M Quintana Giner, M Sowjanya Reddy, M Valdés Chávarri, M Grazia Rossi, Maarten Simoons, Maayan Konigstein, Maciej Lesiak, Maciej Olsowka, Mafalda Selas, Magalie Corfias, Magdalena Madero Rovalo, Magdalena Łanocha, Magdalena Miller, Magdalena Misztal-Teodorczyk, Magdalena Rantinella, Magdy Abdelhamid, Magnolia Jimenez, Mahboob Alam, Mahevamma Mylarappa, Mahfouz El Shahawy, Mahmoud Mohamed, Mahmud Al-Bustami, Majo X Joseph, Malgorzata Frach, Małgorzta Celińska-Spodar, Malte Helm, Manas Chacko, Mandy Murphy, Manitha Vinod, Manjula Rani, Manu Dhawan, Manuela Mombelli, Marcel Weber, Marcello Galvani, Marcelo Jamus Rodrigues, Marcia F Dubin, Marcia F Werner Bayer, Marcin Szkopiak, Marco Antonio Monsalve, Marco Bizzaro Santos, Marco Magnoni, Marco Marini, Marco Sicuro, Marco Zenati, Marcos Valério Coimbra Resende, Marek Roik, Margalit Bentzvi, Margaret Gilsenan, Margaret Iraola, Margot C Quinn, Maria A Alfonso, Maria Antonieta Pereira Moraes, María Dolores Martínez-Ruíz, María Fernanda Canales, Maria Inês Caetano, Maria P Corral, Maria Pérez García, Maria Victoria Actis, Maria Aguirre, Maria Andreasson, Maria Aprile, Maria Colton, Maria Eugenia Martin, Maria Lasala, Maria Lorenzo, Maria Posada, Maria Shier, Maria Thottam, Mariana V Furtado, Mariana Yumi Okada, Marianna D A Dracoulakis, Marianne De Andrade, Mariano Rubio, Marie Essermark, Marielle Scherrer-Crosbie, Marija T Petrovic, Marija Zdravkovic, Marilyn Black, Marina Garcia, Mario J Garcia, Mariola Szulik, Marisa Orgera, Mark A de Belder, Mark Harbinson, Mark Hyun, Mark Peterson, Mark Xavier, Marlowe Mosley, Marta Capinha, Marta Marcinkiewicz-Siemion, Marta Swiderek, Martha Meyer, Martina Ceseri, Martina Tricoli, Marvin Kronenberg, Mary Williams, Mary Ann Champagne, Mary Colleen Rogge, Mary R Soltau, Mary Streif, Massimo Villella, Massoud Leesar, Matei Claudia, Mateusz Solecki, Matías Nicolás Mungo, Matthew Wall Jr, Matthew Budoff, Matthew Jezior, Matthew Luckie, Matthias Friedrich, Mauren P Haeffner, Maximilian Tscharre, Max-Paul Winter, Mayana Almeida, Mayil S Krishnam, Mayuri Patel, Meenakshi Mishra, Megan Manocchia, Meghana Kakade, Melanie J Munro, Melissa D Chaplin, Melissa LeFevre, Mervyn Andiapen, Michael A Gibson, Michael B Rubens, Michael C Turner, Michael D Shapiro, Michael W Lee, Michael Berlowitz, Michael Davidson, Michael Mack, Michael McDaniel, Michael Mumma, Michal Wlodarczyk, Michel G Khouri, Michel S Slama, Michele Rawlins, Michelle M Bonner, Michelle M Seib, Michelle Chang, Michelle Crowder, Michelle Dixon, Michelle Mayon, Michelle McEvoy, Michelle Yee, Miguel M Fernandes, Miguel Nobre Menezes, Miguel Souto Bayarri, Miguel Barrero, Mikhail T Torosoff, Milan R Dobric, Milan Dobric, Milica Nikola Dekleva, Milind Avdhoot Gadkari, Millie Gomez, Min Tun Kyaw, Miriam Brooks, Miroslav Stevo Martinovic, Mitchel B Lustre, Mohammad Tariq Vakani, Mohammad El-Hajjar, Mohammed Al-Amoodi, Mohammed Hussain, Mohammed Saleem, Moisés Blanco-Calvo, Moisés Jiménez-Santos, Mona Bhatia, Monica Rosca, Monika Laukyte, Montserrat Gracida Blanca, Montserrat Vila Perales, Mouaz H Al-Mallah, Moysés de Oliveira Filho, Mpiko Ntsekhe, Muhamed Saric, Mulei Chen, Myriam Brousseau, Myrthes Emy Takiuti, Nada Cemerlic-Adjic, Nadia Asif, Nadia Gakou, Nafisa Hussain, Nana O Katamadze, Nancy L Clapp, Nancy Aedy, Nandita Nataraj, Nanette K Wenger, Naomi Uchida, Nasrul Ismail, Natalia S Oliveira, Natalia de Carvalho Maffei, Natalie Spitzer, Natasha C Putnam, Naved Aslam, Neamat Mowafy, Neeraj Pandit, Neeraj Parakh, Nevena Garcevic, Ngaire Meadows, Nhi N Tran, Nicholas Danchin, Nicki Lakeman, Nicola Johnston, Nicolas W Shammas, Nicole Saint Vrestil, Nicole Deming, Nier Zhong, Niket Patel, Nikola N Boskovic, Nikolaos Karogiannis, Nikos Werner, Nina Johnston, Ning Zhang, Ning Zhou, Niree Hindoyan, Nirmal Kumar, Nitika Chadha, Nitish Naik, Nodira Aripova, Noloyiso Mtana, Nona A Eskelson, Noor Syamira Mokhtar, Noppon Taksaudom, Nor Asiah Basri, Nora Marchelletta, Norma Hogg, Nungshi Jungla, Nuno Ferreira, Oksana A Lubyanaya, Olga B Nikolaeva, Olga Cañavate, Olga Sobrino, Olga Walesiak, Olga Walter, Olga Zdończyk, Olivia J Lim, Olivia Anaya, Olivia Mancilla, Olivier Dubourg, Olugbenga Bello, Omar Almousalli, Omar Thompson, Oni Olurinde, Or Harel, Osama Raheem, Oscar Méndiz, Óscar Prada-Delgado, Oz Shapira, P Christian Schulze, Pachara Panpunuan, Pal Maurovich-Horvat, Pallav Garg, Paloma Moraga, Pam Singh, Pamela Julian, Pamela Ouyang, Pamela Sigel, Pamela Woodard, Panpan Zhou, Paola Emanuela Poggio, Paola Smanio, Paolo Calabro, Paramjit Jeetley, Pascal Goube, Patricia K Nguyen, Patricia Alarie, Patricia Arakelian, Patricia Arsenault, Patricia Blaise, Patricia Brito, Patricia Cowper, Patricia Endsley, Patricia Mieses, Patrick B Alexander, Patrick Donnelly, Patrick Wilmot, Patrycja Lebioda, Paul C Gordon, Paul Der Mesropian, Paul Galiwango, Paul Hauptman, Paul Kennedy, Paula Beardsley, Paula García-González, Paulo Cury Rezende, Paulo Ricardo Caramori, Pavel S Kozlov, Pedro Canas Silva, Pedro Gabriel Melo Barros E Silva, Pedro Píccaro de Oliveira, Pedro Carvalho, Pedro Modas, Pedro Rio, Peeyush Jain, Peiyu He, Peter A McCullough, Peter H Stone, Peter M Pollak, Peter Douglass, Peter Henriksen, Peter OKane, Peter Ong, Philip Jones, Philip Rogal, Philippe Généreux, Philippe Menasche, Philippe Rheault, Phoebe Goold, Pierre Gervais, Pierre Michaud, Pilar Calvillo, Ping Chai, Piotr Jakubowski, Piotr Pruszczyk, Piotr Slomka, Piyamitr Sritara, Poay-Huan Loh, Poonam Sonawane, Pouneh Samadi, Pragnesh P Parikh, Prakash Deedwania, Pranav M Patel, Praneeth Polamuri, Pratiksha Sharma, Precilia Vasquez, Preeti Kamath, Prince Thomas, Priyadarshani Arambam, Puja K Mehta, Purvez Grant, Pushpa Naik, Qi Zhong, Qian Zhao, Qiang Zhou, Qianqian Yuan, Qin Yu, Qingxian Li, Qiulan Xie, Qiutang Zeng, R J Vindhya, R James Gerlach, Rachel King, Rada Vučić, Radmila Lyubarova, Radoslaw Pracon, Raewyn Fisher, Rafael Beyar, Rafael Diaz, Rafael Selgas, Raffaele Bugiardini, Raffaele Fanelli, Raisa Kavalakkat, V S Rajalekshmi, Rajat S Barua, Rajeev Menon, Rajesh Gopalan Nair, Rajesh Francis, Rajiv Narang, Rakesh Yadav, Ralph Alan Huston, T Ramakrishnan, Ramesh de Silva, Rami El Mahmoud, Ramiro Carvalho, Ramon de Jesús-Pérez, Ramona Stevens, Ran Leng, Ranjan Kachru, Ranjit Kumar Nath, Raquel Sanchez, Raven R Dwyer, Raven Lee, Ray Wyman, Raymond C Wong, Raymond W Little, Raymundo Ocaranza Sanchez, Rebecca J Wimmer, Rebecca Bariciano, Rebecca Otis, Rebekah R Herrmann, Reem Yunis, Reinette Hampson, Renato Abdala Karam, Renee C Hessian, Renee Kaneshiro, Reshma Ravindran, Reto Andreas Gamma, Reyna Bhandari, Reza Arsanjani, Ricardo L Lopes, Ricardo Mendes Oliveira, Ricardo Costa, Richa Bhatt, Richard F Davies, Richard H J Trimlett, Richard Goldweit, Rik Hermanides, Rine Nakanishi, Rinu R Sidh, Risha Patel, Rita Coram, Rizwan A Siddiqui, Rob S Beanlands, Robert J Hamburger, Robert K Riezebos, Robert M Donnino, Robert Bojar, Robert Chilton, Robert Guyton, Robert Henderson, Robert Kornberg, Robert Leber, Robert Mao, Robert Stenberg, Roberta P Santos, Roberto René Favaloro, Roberto Amati, Rodolfo G S D Lima, Rodrigo J Cerci, Rogerio Tumelero, Rohit Tandon, Roma Tewari, Romalisa Miranda-Peats, Ron Wald, Ronald A Mastouri, Ronald G Morford, Ronald G Schwartz, Ronald P Pedalino, Rongrong Hu, Ronnell A Hansen, Ronny A Cohen, Rory Hachamovitch, Rosa Homem, Rosa Sandonato, Rosane Laimer, Rosann Gans, Roxanne Yost, Roy Mathew, Rubén Baleón-Espinosa, Ruben Ramos, Rubine Gevorgyan, Rui Ferreira, Rui Jing, Ruth Pérez-Fernández, S K Dwivedi, S Ramakrishnan, Saadat Khan, Sabahat Bokhari, Sabu Thomas, Sadath Lubna, Sajeeda Parveen Khan, Sajeev Chakanalil Govindan, Saket Girotra, Saleem Kassam, Sallie Canada, Salvador Cruz-Flores, Samaa Mohamed, Samantha Ly, Sameh El Kaffas, Samia Massalha, Sampoornima Setty, Samuel Nwosu, Sandeep Seth, Sandeep Singh, Sander R Niehe, Sandra M Rivest, Sandra S Zier, Sandra Ahoud, Sandy Carr, Sanjay Ganapathi, Sanjay Shetty, Sanjeev Sharma, Santa Jimenez, Santhosh Satheesh, Santiago A Garcia, Sara Fernandez, Sara Karlsson, Sara Salkind, Sara Temiyasathit, Sarah Medina Rodriguez, Sarah Beaudry, Sarah Hadjih, Sarah Williams, Sarah Zahrani, Sarju Ralhan, Sasa Hinic, Sasko Kedev, Satinder Singh, Satoshi Yasuda, Satvic Cholenahally Manjunath, Sau Lee, Scott M Kaczkowski, Scott Kinlay, Sean W Hayes, Sebastian Sobczak, Senait Asier, Sergey A Sayganov, Seth I Sokol, Shaheen Pandie, Shaiful Azmi Yahaya, Shamir Mehta, Shao-Ping Nie, Sharad Chandra, Sharder Islam, Sharon Tai, Sheetal Rupesh Karwa, Sheri Ussery, Sheromani Bajaj, Sherron C Crook, Shigeyuki Nishimura, Shintaro Nakano, Shirin Heydari, Shiv Kumar Choudhary, Shivali Patel, Shobana Ganesan, Shruti Pandey, Shuyang Zhang, Shweta Hande, Siddharth Gadage, Sik-Yin V Tan, Silvia Zottis Poletti, Silvia Riera, Silvia Valbuena, Simon Walsh, Simona Maspoli, Simone Savaris, Si-Ting Feng, So Yang Cho, Solomon Yakubov, Songlin Zhu, Songtao Wang, Sonia Guerrero, Sonika Gupta, Sonja Salinger Martinovic, Sonya Brons, Sorin Brener, Sothinathan Gurunathan, Souheil Saba, Soundarya Nayak, Sowjanya Reddy, Srinivasa Potluri, Sriram Sudarshan, Srun Kuanprasert, Stacie Van Oosterhout, Stamatios Lerakis, Stanley E Cobos, Stefan C Bertog, Stefan M Simović, Stefan Weikl, Stefano Di Marco, Stefano Provasoli, Stephanie A Tirado, Stephanie C Boer, Stephanie M Lane, Stephanie Ferket, Stephanie Kelly, Stephanie Wasmiller, Stephen H McKellar, Stephen P Hoole, Stephen Fremes, Stephen Preston, Steve Leung, Steven A Fein, Steven J Lindsay, Steven P Sedlis, Steven Giovannone, Steven Michael, Steven Weitz, Stijn van Vugt, Subhash Banerjee, Sudhir Naik, Suellen Hosino, Sukie Desire, Sukit Yamwong, Suku T Thambar, Sulagna Mookherjee, Suman Singh, Sundeep Mishra, Sunil Kumar Verma, Supap Kulthawong, Supatchara Khwakhong, Surendra Naik, Suresh Babu, Surin Woragidpoonpol, Suryaprakash Narayanappa, 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Youn, Trish Tucker, Trudie Milner, Tuhina Bose, Tushar Kotecha, Udo Sechtem, Uma S Valeti, Umberto Cucchini, Umesh Badami, Upendra Kaul, V K Bahl, V S Narain, Valentina Casali, Valeria Godoy, Valerie Robesyn, Vamshi P Priya, Vandana Yadav, Vera McKinney, Veronica De Lenges, Veronica Tinnirello, Vicente Miro, Victor Navarro, Victoria Gumerova, Victoria Hernandez, Vidya Seeratan, Vijay Kumar, Vikentiy Y Kozulin, Viktoria Bulkley, Vilmar Veiga Jr, Vincent Setang, C P Vineeth, Virginai Pubull Nuñez, Virginia Fernández-Figares, Vitor Gomes, Viviana Gabriel, Viviane Dos Santos, Viviane Almeida, Vlad A Iliescu, Vladan Mudrenovic, Vladimir Dzavik, Vojislav L Giga, Walter Enrique Mogrovejo, Wan Xian Chan, Wanda C Marfori, Wanda Parker, Warangkana Mekara, Wassim Nona, Wayne Old, Wayne Pennachi, Weerachai Nawarawong, Wei Chen, Wei Su, Weibing Xing, Wei-Ren Lan, Wenda Crawford, Wendy L Stewart, Wendy Drewes, Wenhua Lin, William B Abernethy, William D Salerno, William F Fearon, William Vergoni, 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Rita Francisco, Ana S Mladenovic, Ana Santana, Anam Siddiqui, Anastasia M Kuzmina-Krutetskaya, Andras Vertes, Andre S Sousa, Andre Gabriel, André Schmidt, Andrea M Lundeen, Andrea Bartykowszki, Andrea Lorimer, Andrea Mortara, Andrea Pascual, Andreia Coelho, Andreia Rocha, Andrés García-Rincón, Andrew G Howarth, Andrew J Moriarty, Andrew Docherty, Andrew Starovoytov, Andrew Zurick, Andrzej Łabyk, Andrzej Swiatkowski, Andy Lam, Anelise Kawakami, Angela Hoye, Angela Kim, Angelique Smit, Angelo Nobre, Anil V Shah, Anja Ljubez, Anjali Anand, Ankush Sachdeva, Ann Greenberg, Ann Luyten, Ann Ostrander, Anna Di Donato, Anna Cichocka-Radwan, Anna Fojt, Anna Plachcinska, Anna Proietti, Anna Teresinska, Anne Marie Webb, Anne Cartwright, Anne Heath, Anne Mackin, Anong Amaritakomol, Anong Chaiyasri, Anoop Chauhan, Anoop Mathew, Anthony Gemignani, Anto Luigi Andres, Antonia Vega, Antonietta Hansen, Antonino Ginel Iglesias, Antonio Carlos Carvalho, Antonio Di Chiara, Antonio Serra Peñaranda, Antonio 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Bermudez, Eapen Punnoose, Edgar L Tay, Edgar Karanjah, Edoardo Verna, Eduardo Hernandez-Rangel, Edward D Nicol, Edward O McFalls, Edward T Martin, Edyta Kaczmarska, Ekaterina I Lubinskaya, Elena A Demchenko, Elena Refoyo Salicio, Eli Feen, Elihú Durán-Cortés, Elisabeth M Janzen, Elise L Hannemann, Elise van Dongen, Elissa Restelli Piloto, Eliza Kaplan, Elizabeta Srbinovska Kostovska, Elizabeth Capasso-Gulve, Elizabeth Congdon, Elizabeth Ferguson, Elizaveta V Zbyshevskaya, Ellen Magedanz, Ellie Fridell, Ellis W Lader, Elvin Kedhi, Emanuela Racca, Emilie Tachot, Emily DeRosa, Encarnación Alonso-Álvarez, Eric Nicollet, Eric Peterson, Erick Alexánderson Rosas, Erick Donato Morales, Erin Orvis, Ermina Moga, Estelle Montpetit, Estevao Figueiredo, Eugene Passamani, Eugenia Nikolsky, Eunice Yeoh, Evgeniy I Kretov, Ewa Szczerba, Ewelina Wojtala, Expedito Eustáquio Ribeiro Silva, F Marin Ortuño, Fabio R Farias, Fabio Fimiani, Fabrizio Rolfo, Fa-Chang Yu, Fadi Hage, Fadi Matar, Fahim Haider 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Hayley Pomeroy, Heather Barrentine, Heather Golden, Heather Hurlburt, Heidi Wilson, Helen C Tucker, Helene Abergel, Hemalata Siddaram, Hermine Osseni, Herwig Schuchlenz, Hesong Zeng, Hicham Skali, Hilda Solomon, Hollie Horton, Holly Hetrick, Holly Little, Holly Park, Hongjie Chi, Hossam Mahrous, Howard A Levite, Hristo Pejkov, Huajun Li, Hugo Bloise-Adames, Hugo Marques, Hui Zhong, Hui-Min Zhang, Humayrah Hashim, Hung-I Yeh, Hussien El Fishawy, Ian Webb, Iftikhar Kullo, Igor O Grazhdankin, Ihab Hamzeh, Ikraam Hassan, Ikuko Ueda, Ileana L Pina, Ilona Tamasauskiene, Ilse Bouwhuis, Imran Arif, Ina Wenzelburger, Inês Zimbarra Cabrita, Ines Rodrigues, Inga H Robbins, Inga Soveri, Ingela Schnittger, Iqbal Karimullah, Ira M Dauber, Iram Rehman, Irena Peovska Mitevska, Irene Marthe Lang, Irina Subbotina, Irma Kalibataite-Rutkauskiene, Irni Yusnida, Isabel Estela Carvajal, Isabella C Palazzo, Isabelle Hogan, Isabelle Roy, Ishba Syed, Ishita Tejani, Ivan A Naryshkin, Ivana Jankovic, Iwona Niedzwiecka, J David Knight, Jacek Kusmierek, Jackie M White, Jackie Chow, Jacob Udell, Jacqueline E Tamis-Holland, Jacqueline Fannon, Jacquelyn A Quin, Jacquelyn Do, Jaekyeong Heo, Jakub Maksym, James E Davies, James H O'Keefe Jr, James J Jang, James Cha, James Harrison, James Hirsch, James Stafford, James Tatoulis, Jamie Rankin, Jan Henzel, Jan Orga, Jana Tancredi, Janaina Oliveira, Jane Burton, Jane Eckstein, Jane Marucci, Janet P Knight, Janet Blount, Janet Halliday, Janetta Kourzenkova, Janitha Raj, Jan-Malte Sinning, Jaqueline Pozzibon, Jaroslaw Drozdz, Jaroslaw Karwowski, Jason D Glover, Jason Loh Kwok, Jason T Call, Jason Linefsky, Jassira Gomes, Jati Anumpa, Javier J Garcia, Javier Courtis, Jay Meisner, K Jayakumar, Jayne Scales, Jean E Denaro, Jean Michel Juliard, Jean Ho, Jeanette K Stansborough, Jean-Michel Juliard, Jeanne Russo, Jeannette J M Schoep, Jeet Thambyrajah, Jeff Leimberger, Jeffery A Breall, Jeffrey A Kohn, Jeffrey C Milliken, Jeffrey Anderson, Jeffrey Blume, 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John Doan, John Kotter, John Kurian, John Mukai, John Pownall, Jolanta Sobolewska, Jon Kobashigawa, Jonathan L Goldberg, Jonathan W Bazeley, Jonathan Byrne, Jonathan Himmelfarb, Jonathan Leipsic, Jonean Thorsen, Jorge F Trejo Gutierrez, Jorge Escobedo, Jorik Timmer, José A Ortega-Ramírez, José Antonio Marin-Neto, Jose D Salas, Jose Enrique Castillo, Jose Francisco Saraiva, José J Cuenca-Castillo, Jose L Diez, José Luis Narro Villanueva, José Luiz da Vieira, José M Flores-Palacios, Jose Ramon Gonzalez, Jose Seijas Amigo, Jose Fragata, Josep Maria Padró, Josheph F X McGarvey Jr, Joseph Hannan, Joseph Sacco, Joseph Sweeny, Joseph Wiesel, Josephine D Abraham, Joshua P Loh, Joy Burkhardt, Joyce R White, Joyce Riestenberg-Smith, Judit Sebo, Judith L Meadows, Judith Wright, Judy Mae Foltz, Judy Hung, Judy Otis, Juergen Stumpf, Jui-Peng Tsai, Julia S Dionne, Julia de Aveiro Morata, Julie Bunke, Julie Morrow, Julio César Figal, Jun Fujita, Jun Jiang, Junhua Li, Junqing Yang, Juntima Euathrongchit, Jyotsna Garg, K Manjula Rani, K Preethi, Kaatje Goetschalckx, Kai Eggers, Kamalakar Surineni, Kanae Hirase, T R Kapilamoorthy, Karen Calfas, Karen Gratrix, Karen Hallett, Karen Hultberg, Karen Nugent, Karen Petrosyan, Karen Swan, Karolina Kryczka, Karolina Wojtczak-Soska, Karolina Wojtera, Karsten Lenk, Karthik Ramasamy, Katarzyna Łuczak, Katarzyna Malinowska, Kate Pointon, Kate Robb, Katherine Martin, Kathleen Claes, Kathryn Carruthers, Kathy E Siegel, Katia Drouin, Katie Fowler-Lehman, Kavita Rawat, Kay Rowe, Keiichi Fukuda, Keith A A Fox, Ken Mahaffey, Kendra Unterbrink, Kenneth Giedd, Kerrie Van Loo, Kerry Lee, Kerstin Bonin, Kevin R Bainey, Kevin T Harley, Kevin Anstrom, Kevin Chan, Kevin Croce, Kevin Landolfo, Kevin Marzo, Keyur Patel, Khaled Abdul-Nour, Khaled Alfakih, Khaled Dajani, Khaled Ziada, Khaula Baloch, Khrystyna Kushniriuk, Kian-Keong Poh, Kim F Ireland, Kim Holland, Kimberly Ann Byrne, Kimberly E Halverson, Kimberly Elmore, Kimberly Miller-Cox, Kiran Reddy, Kirsten J Quiles, Kirsty Abercrombie, Klaus Matschke, Konrad Szymczyk, Koo Hui Chan, Kotiboinna Preethi, Kozhaya Sokhon, Krissada Meemuk, Kristian Thygesen, Kristin M Salmi, Kristin Newby, Kristina Wippler, Kristine Arges, Kristine Teoh, Krystal Etherington, Krystyna Łoboz-Grudzień, Krzysztof W Reczuch, Krzysztof Bury, Krzysztof Drzymalski, Krzysztof Kukuła, Kuo-Tzu Sung, Kurt Huber, Ladda Douangvila, Lance Sullenberger, Larissa Miranda Trama, Laszlone Matics, Laura Drew, Laura Flint, Laura Keinaite, Laura Sarti, Laurel Kolakaluri, Lawrence M Phillips, Lawrence Friedman, Lawrence Phillips, Lazar Velicki, Leah Howell, Leandro C Maranan, Leanne Cox, Ledjalem Daba, Lei Zhang, Lekshmi Dharmarajan, Leo Bockeria, Leonardo Pizzol Caetano, Leonardo Bridi, Leonid L Bershtein, Leszek Sokalski, Li Hai Yan, Li Li, Lia Nijmeijer, Lidia Sousa, Lihong Xu, Lihua Zhang, Lili Zhang, Lilia Schiavi, Lilian Mazza Barbosa, Lillian L Khor, Lina Felix-Stern, Linda L Hall, Linda M Hollenweger, Linda Arcand, Linda Davidson-Ray, Linda Schwarz, Lindsey N Sikora, Lingping Chi, Lino Patricio, Liping Zhang, Lisa Chaytor, Lisa Hatch, Lisa McCloy, Lisa Wong, Liselotte Persson, Lixin Jiang, Liz Low, Ljiljana Pupic, Loïc Bière, Lorenzo Monti, Lori Christensen, Lori Pritchard, Loriane Black, Lori-Ann Desimone, Lori-Ann Larmand, Lorraine McGregor, Louise Morby, Louise Thomson, Luc Harvey, Luciana de Pádua Baptista, Lucilla Garcia, Ludivine Eliahou, Ludmila Helmer, Luis F Smidt, Luis Bernanrdes, Luis Guzman, Luiz A Carvalho, Luyang Xiong, Lynette L Teo, Lynn M Neeson, Lynne Winstanley, M Barbara Srichai-Parsia, M Quintana Giner, M Sowjanya Reddy, M Valdés Chávarri, M Grazia Rossi, Maarten Simoons, Maayan Konigstein, Maciej Lesiak, Maciej Olsowka, Mafalda Selas, Magalie Corfias, Magdalena Madero Rovalo, Magdalena Łanocha, Magdalena Miller, Magdalena Misztal-Teodorczyk, Magdalena Rantinella, Magdy Abdelhamid, Magnolia Jimenez, Mahboob Alam, Mahevamma Mylarappa, Mahfouz El Shahawy, Mahmoud Mohamed, Mahmud Al-Bustami, Majo X Joseph, Malgorzata Frach, Małgorzta Celińska-Spodar, Malte Helm, Manas Chacko, Mandy Murphy, Manitha Vinod, Manjula Rani, Manu Dhawan, Manuela Mombelli, Marcel Weber, Marcello Galvani, Marcelo Jamus Rodrigues, Marcia F Dubin, Marcia F Werner Bayer, Marcin Szkopiak, Marco Antonio Monsalve, Marco Bizzaro Santos, Marco Magnoni, Marco Marini, Marco Sicuro, Marco Zenati, Marcos Valério Coimbra Resende, Marek Roik, Margalit Bentzvi, Margaret Gilsenan, Margaret Iraola, Margot C Quinn, Maria A Alfonso, Maria Antonieta Pereira Moraes, María Dolores Martínez-Ruíz, María Fernanda Canales, Maria Inês Caetano, Maria P Corral, Maria Pérez García, Maria Victoria Actis, Maria Aguirre, Maria Andreasson, Maria Aprile, Maria Colton, Maria Eugenia Martin, Maria Lasala, Maria Lorenzo, Maria Posada, Maria Shier, Maria Thottam, Mariana V Furtado, Mariana Yumi Okada, Marianna D A Dracoulakis, Marianne De Andrade, Mariano Rubio, Marie Essermark, Marielle Scherrer-Crosbie, Marija T Petrovic, Marija Zdravkovic, Marilyn Black, Marina Garcia, Mario J Garcia, Mariola Szulik, Marisa Orgera, Mark A de Belder, Mark Harbinson, Mark Hyun, Mark Peterson, Mark Xavier, Marlowe Mosley, Marta Capinha, Marta Marcinkiewicz-Siemion, Marta Swiderek, Martha Meyer, Martina Ceseri, Martina Tricoli, Marvin Kronenberg, Mary Williams, Mary Ann Champagne, Mary Colleen Rogge, Mary R Soltau, Mary Streif, Massimo Villella, Massoud Leesar, Matei Claudia, Mateusz Solecki, Matías Nicolás Mungo, Matthew Wall Jr, Matthew Budoff, Matthew Jezior, Matthew Luckie, Matthias Friedrich, Mauren P Haeffner, Maximilian Tscharre, Max-Paul Winter, Mayana Almeida, Mayil S Krishnam, Mayuri Patel, Meenakshi Mishra, Megan Manocchia, Meghana Kakade, Melanie J Munro, Melissa D Chaplin, Melissa LeFevre, Mervyn Andiapen, Michael A Gibson, Michael B Rubens, Michael C Turner, Michael D Shapiro, Michael W Lee, Michael Berlowitz, Michael Davidson, Michael Mack, Michael McDaniel, Michael Mumma, Michal Wlodarczyk, Michel G Khouri, Michel S Slama, Michele Rawlins, Michelle M Bonner, Michelle M Seib, Michelle Chang, Michelle Crowder, Michelle Dixon, Michelle Mayon, Michelle McEvoy, Michelle Yee, Miguel M Fernandes, Miguel Nobre Menezes, Miguel Souto Bayarri, Miguel Barrero, Mikhail T Torosoff, Milan R Dobric, Milan Dobric, Milica Nikola Dekleva, Milind Avdhoot Gadkari, Millie Gomez, Min Tun Kyaw, Miriam Brooks, Miroslav Stevo Martinovic, Mitchel B Lustre, Mohammad Tariq Vakani, Mohammad El-Hajjar, Mohammed Al-Amoodi, Mohammed Hussain, Mohammed Saleem, Moisés Blanco-Calvo, Moisés Jiménez-Santos, Mona Bhatia, Monica Rosca, Monika Laukyte, Montserrat Gracida Blanca, Montserrat Vila Perales, Mouaz H Al-Mallah, Moysés de Oliveira Filho, Mpiko Ntsekhe, Muhamed Saric, Mulei Chen, Myriam Brousseau, Myrthes Emy Takiuti, Nada Cemerlic-Adjic, Nadia Asif, Nadia Gakou, Nafisa Hussain, Nana O Katamadze, Nancy L Clapp, Nancy Aedy, Nandita Nataraj, Nanette K Wenger, Naomi Uchida, Nasrul Ismail, Natalia S Oliveira, Natalia de Carvalho Maffei, Natalie Spitzer, Natasha C Putnam, Naved Aslam, Neamat Mowafy, Neeraj Pandit, Neeraj Parakh, Nevena Garcevic, Ngaire Meadows, Nhi N Tran, Nicholas Danchin, Nicki Lakeman, Nicola Johnston, Nicolas W Shammas, Nicole Saint Vrestil, Nicole Deming, Nier Zhong, Niket Patel, Nikola N Boskovic, Nikolaos Karogiannis, Nikos Werner, Nina Johnston, Ning Zhang, Ning Zhou, Niree Hindoyan, Nirmal Kumar, Nitika Chadha, Nitish Naik, Nodira Aripova, Noloyiso Mtana, Nona A Eskelson, Noor Syamira Mokhtar, Noppon Taksaudom, Nor Asiah Basri, Nora Marchelletta, Norma Hogg, Nungshi Jungla, Nuno Ferreira, Oksana A Lubyanaya, Olga B Nikolaeva, Olga Cañavate, Olga Sobrino, Olga Walesiak, Olga Walter, Olga Zdończyk, Olivia J Lim, Olivia Anaya, Olivia Mancilla, Olivier Dubourg, Olugbenga Bello, Omar Almousalli, Omar Thompson, Oni Olurinde, Or Harel, Osama Raheem, Oscar Méndiz, Óscar Prada-Delgado, Oz Shapira, P Christian Schulze, Pachara Panpunuan, Pal Maurovich-Horvat, Pallav Garg, Paloma Moraga, Pam Singh, Pamela Julian, Pamela Ouyang, Pamela Sigel, Pamela Woodard, Panpan Zhou, Paola Emanuela Poggio, Paola Smanio, Paolo Calabro, Paramjit Jeetley, Pascal Goube, Patricia K Nguyen, Patricia Alarie, Patricia Arakelian, Patricia Arsenault, Patricia Blaise, Patricia Brito, Patricia Cowper, Patricia Endsley, Patricia Mieses, Patrick B Alexander, Patrick Donnelly, Patrick Wilmot, Patrycja Lebioda, Paul C Gordon, Paul Der Mesropian, Paul Galiwango, Paul Hauptman, Paul Kennedy, Paula Beardsley, Paula García-González, Paulo Cury Rezende, Paulo Ricardo Caramori, Pavel S Kozlov, Pedro Canas Silva, Pedro Gabriel Melo Barros E Silva, Pedro Píccaro de Oliveira, Pedro Carvalho, Pedro Modas, Pedro Rio, Peeyush Jain, Peiyu He, Peter A McCullough, Peter H Stone, Peter M Pollak, Peter Douglass, Peter Henriksen, Peter OKane, Peter Ong, Philip Jones, Philip Rogal, Philippe Généreux, Philippe Menasche, Philippe Rheault, Phoebe Goold, Pierre Gervais, Pierre Michaud, Pilar Calvillo, Ping Chai, Piotr Jakubowski, Piotr Pruszczyk, Piotr Slomka, Piyamitr Sritara, Poay-Huan Loh, Poonam Sonawane, Pouneh Samadi, Pragnesh P Parikh, Prakash Deedwania, Pranav M Patel, Praneeth Polamuri, Pratiksha Sharma, Precilia Vasquez, Preeti Kamath, Prince Thomas, Priyadarshani Arambam, Puja K Mehta, Purvez Grant, Pushpa Naik, Qi Zhong, Qian Zhao, Qiang Zhou, Qianqian Yuan, Qin Yu, Qingxian Li, Qiulan Xie, Qiutang Zeng, R J Vindhya, R James Gerlach, Rachel King, Rada Vučić, Radmila Lyubarova, Radoslaw Pracon, Raewyn Fisher, Rafael Beyar, Rafael Diaz, Rafael Selgas, Raffaele Bugiardini, Raffaele Fanelli, Raisa Kavalakkat, V S Rajalekshmi, Rajat S Barua, Rajeev Menon, Rajesh Gopalan Nair, Rajesh Francis, Rajiv Narang, Rakesh Yadav, Ralph Alan Huston, T Ramakrishnan, Ramesh de Silva, Rami El Mahmoud, Ramiro Carvalho, Ramon de Jesús-Pérez, Ramona Stevens, Ran Leng, Ranjan Kachru, Ranjit Kumar Nath, Raquel Sanchez, Raven R Dwyer, Raven Lee, Ray Wyman, Raymond C Wong, Raymond W Little, Raymundo Ocaranza Sanchez, Rebecca J Wimmer, Rebecca Bariciano, Rebecca Otis, Rebekah R Herrmann, Reem Yunis, Reinette Hampson, Renato Abdala Karam, Renee C Hessian, Renee Kaneshiro, Reshma Ravindran, Reto Andreas Gamma, Reyna Bhandari, Reza Arsanjani, Ricardo L Lopes, Ricardo Mendes Oliveira, Ricardo Costa, Richa Bhatt, Richard F Davies, Richard H J Trimlett, Richard Goldweit, Rik Hermanides, Rine Nakanishi, Rinu R Sidh, Risha Patel, Rita Coram, Rizwan A Siddiqui, Rob S Beanlands, Robert J Hamburger, Robert K Riezebos, Robert M Donnino, Robert Bojar, Robert Chilton, Robert Guyton, Robert Henderson, Robert Kornberg, Robert Leber, Robert Mao, Robert Stenberg, Roberta P Santos, Roberto René Favaloro, Roberto Amati, Rodolfo G S D Lima, Rodrigo J Cerci, Rogerio Tumelero, Rohit Tandon, Roma Tewari, Romalisa Miranda-Peats, Ron Wald, Ronald A Mastouri, Ronald G Morford, Ronald G Schwartz, Ronald P Pedalino, Rongrong Hu, Ronnell A Hansen, Ronny A Cohen, Rory Hachamovitch, Rosa Homem, Rosa Sandonato, Rosane Laimer, Rosann Gans, Roxanne Yost, Roy Mathew, Rubén Baleón-Espinosa, Ruben Ramos, Rubine Gevorgyan, Rui Ferreira, Rui Jing, Ruth Pérez-Fernández, S K Dwivedi, S Ramakrishnan, Saadat Khan, Sabahat Bokhari, Sabu Thomas, Sadath Lubna, Sajeeda Parveen Khan, Sajeev Chakanalil Govindan, Saket Girotra, Saleem Kassam, Sallie Canada, Salvador Cruz-Flores, Samaa Mohamed, Samantha Ly, Sameh El Kaffas, Samia Massalha, Sampoornima Setty, Samuel Nwosu, Sandeep Seth, Sandeep Singh, Sander R Niehe, Sandra M Rivest, Sandra S Zier, Sandra Ahoud, Sandy Carr, Sanjay Ganapathi, Sanjay Shetty, Sanjeev Sharma, Santa Jimenez, Santhosh Satheesh, Santiago A Garcia, Sara Fernandez, Sara Karlsson, Sara Salkind, Sara Temiyasathit, Sarah Medina Rodriguez, Sarah Beaudry, Sarah Hadjih, Sarah Williams, Sarah Zahrani, Sarju Ralhan, Sasa Hinic, Sasko Kedev, Satinder Singh, Satoshi Yasuda, Satvic Cholenahally Manjunath, Sau Lee, Scott M Kaczkowski, Scott Kinlay, Sean W Hayes, Sebastian Sobczak, Senait Asier, Sergey A Sayganov, Seth I Sokol, Shaheen Pandie, Shaiful Azmi Yahaya, Shamir Mehta, Shao-Ping Nie, Sharad Chandra, Sharder Islam, Sharon Tai, Sheetal Rupesh Karwa, Sheri Ussery, Sheromani Bajaj, Sherron C Crook, Shigeyuki Nishimura, Shintaro Nakano, Shirin Heydari, Shiv Kumar Choudhary, Shivali Patel, Shobana Ganesan, Shruti Pandey, Shuyang Zhang, Shweta Hande, Siddharth Gadage, Sik-Yin V Tan, Silvia Zottis Poletti, Silvia Riera, Silvia Valbuena, Simon Walsh, Simona Maspoli, Simone Savaris, Si-Ting Feng, So Yang Cho, Solomon Yakubov, Songlin Zhu, Songtao Wang, Sonia Guerrero, Sonika Gupta, Sonja Salinger Martinovic, Sonya Brons, Sorin Brener, Sothinathan Gurunathan, Souheil Saba, Soundarya Nayak, Sowjanya Reddy, Srinivasa Potluri, Sriram Sudarshan, Srun Kuanprasert, Stacie Van Oosterhout, Stamatios Lerakis, Stanley E Cobos, Stefan C Bertog, Stefan M Simović, Stefan Weikl, Stefano Di Marco, Stefano Provasoli, Stephanie A Tirado, Stephanie C Boer, Stephanie M Lane, Stephanie Ferket, Stephanie Kelly, Stephanie Wasmiller, Stephen H McKellar, Stephen P Hoole, Stephen Fremes, Stephen Preston, Steve Leung, Steven A Fein, Steven J Lindsay, Steven P Sedlis, Steven Giovannone, Steven Michael, Steven Weitz, Stijn van Vugt, Subhash Banerjee, Sudhir Naik, Suellen Hosino, Sukie Desire, Sukit Yamwong, Suku T Thambar, Sulagna Mookherjee, Suman Singh, Sundeep Mishra, Sunil Kumar Verma, Supap Kulthawong, Supatchara Khwakhong, Surendra Naik, Suresh Babu, Surin Woragidpoonpol, Suryaprakash Narayanappa, Susan Derbyshire, Susan Gent, Susan Mathus, Susan Milbrandt, Susan Moore, Susan Regan, Susan Stinson, Susan Webber, Susana Silva, Susanna Stevens, Susanne Gruensfelder, Suthara Aramcharoen, Suvarna Kolhe, Suzana Tavares, Suzanne Arnold, Suzanne Welsh, Svetlana Apostolovic, Swapna Kunhunny, Ta-Chuan Hung, Taissa Zappernick, Tali Sharir, Talita Silva, Tamara Colaiácovo Soares, Tapan Umesh Pillay, Tarun K Mittal, Tatiana Trifonova, Tauane Bello Duarte, Tauqir Huk, Téodora Dutoiu, Terrance Chua, Terry Weyand, Thabitha Charles, Theodoros Kofidis, Theresa McCreary, Thierry Lefevre, Thippeekaa Arumairajah, Thitipong Tepsuwan, Thomas J Mulhearn, Thomas M Meyer, Thomas P Rocco, Thomas R Downes, Thomas Crain, Thomas Haldis, Thomas Mathew, Thomas Redick, Thounaojam Indira Devi, Thuraia Nageh, Tia Cauthren, Tiago Silva, Tiffany Little, Tijana Andric, Tina Harding, Titus Lau, Tiziana Formisano, Tiziano Moccetti, Tomasz Ciurus, Tomasz Mazurek, Tomasz Tarchalski, Toshiyuki Nagai, Tri Tran, Tricia Youn, Trish Tucker, Trudie Milner, Tuhina Bose, Tushar Kotecha, Udo Sechtem, Uma S Valeti, Umberto Cucchini, Umesh Badami, Upendra Kaul, V K Bahl, V S Narain, Valentina Casali, Valeria Godoy, Valerie Robesyn, Vamshi P Priya, Vandana Yadav, Vera McKinney, Veronica De Lenges, Veronica Tinnirello, Vicente Miro, Victor Navarro, Victoria Gumerova, Victoria Hernandez, Vidya Seeratan, Vijay Kumar, Vikentiy Y Kozulin, Viktoria Bulkley, Vilmar Veiga Jr, Vincent Setang, C P Vineeth, Virginai Pubull Nuñez, Virginia Fernández-Figares, Vitor Gomes, Viviana Gabriel, Viviane Dos Santos, Viviane Almeida, Vlad A Iliescu, Vladan Mudrenovic, Vladimir Dzavik, Vojislav L Giga, Walter Enrique Mogrovejo, Wan Xian Chan, Wanda C Marfori, Wanda Parker, Warangkana Mekara, Wassim Nona, Wayne Old, Wayne Pennachi, Weerachai Nawarawong, Wei Chen, Wei Su, Weibing Xing, Wei-Ren Lan, Wenda Crawford, Wendy L Stewart, Wendy Drewes, Wenhua Lin, William B Abernethy, William D Salerno, William F Fearon, William Vergoni, William Weintraub, Winnie C Sia, Wlodzimierz J Musial, Xacobe Flores-Ríos, Xavier Garcia-Moll Marimon, Xi Su, Xiang Ma, Xiangqiong Gu, Xiao Wang, Xiaomei Li, Xiaowei Yao, Xin Fu, Xin Su, Xin Zeng, Xinchun Yang, Xiuhong Li, Xuehua Fang, Xutong Wang, Yaming Geng, Yan Yan, Yanek Pépin-Dubois, Yanfu Wang, Yang Wang, Yanmeng Tian, Yaping Huang, Yechen Han, Yesenia Zambrano, Yi-Hsuan Yang, Ying Tung Sia, Yining Yang, Yitong Ma, Yolayfi Peralta, Yongjian Wu, Yu Kunwu, Yu Zhao, Yudong Peng, Yueh-Hung Lin, Yulan Zhao, Yumei Dong, Yunhai Zhao, Yutthaphan Wannasopha, Yvonne Taul, Zakir Sahul, Zalina Kudzoeva, Zbigniew Kalarus, Zeljko Z Markovic, Zhen Huang, Zheng Ji, Zhenyu Liu, Zhou Yue, Zhulin Zhang, Zhuxi Li, Zile Singh Meharwal, Ziliang Bai, Zixiang Yu, Zohra Huda, Zoltan Davidovits
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Male ,Cardiac Catheterization ,Computed Tomography Angiography ,medicine.medical_treatment ,Myocardial Ischemia ,Coronary Disease ,Coronary Artery Disease ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,Coronary Angiography ,ISCHEMIA Research Group ,law.invention ,Angina ,Coronary artery disease ,0302 clinical medicine ,Randomized controlled trial ,law ,Cardiovascular Disease ,Myocardial Revascularization ,030212 general & internal medicine ,Coronary Artery Bypass ,11 Medical and Health Sciences ,Cardiac catheterization ,General Medicine ,Middle Aged ,humanities ,Cardiovascular Diseases ,Cardiology ,Female ,Human ,medicine.medical_specialty ,Ischemia ,Article ,03 medical and health sciences ,Geriatric cardiology ,Percutaneous Coronary Intervention ,General & Internal Medicine ,Internal medicine ,medicine ,Humans ,Angina, Unstable ,Aged ,business.industry ,Coronary Artery Bypa ,Percutaneous coronary intervention ,Bayes Theorem ,medicine.disease ,Heart failure ,Quality of Life ,business - Abstract
BACKGROUND: Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS: We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS: Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, -1.8 percentage points; 95% CI, -4.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS: Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used. (Funded by the National Heart, Lung, and Blood Institute and others; ISCHEMIA ClinicalTrials.gov number, NCT01471522.).
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- 2020
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6. How biased are our models? – a case study of the alpine region
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D. Degen, C. Spooner, M. Scheck-Wenderoth, and M. Cacace
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Work (thermodynamics) ,QE1-996.5 ,Physical model ,Basis (linear algebra) ,business.industry ,Calibration (statistics) ,Computer science ,Geothermal energy ,Process (computing) ,0211 other engineering and technologies ,Geology ,02 engineering and technology ,Parameter space ,010502 geochemistry & geophysics ,01 natural sciences ,ddc:550 ,Sensitivity (control systems) ,021108 energy ,business ,Algorithm ,0105 earth and related environmental sciences - Abstract
Geoscientific model development : GMD 14(11), 7133-7153 (2021). doi:10.5194/gmd-14-7133-2021, Published by Copernicus, Katlenburg-Lindau
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- 2021
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7. Improving access to primary health care: a cross-case comparison based on an a priori program theory
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Nigel Stocks, Cathie Scott, Virginia Lewis, Impact team, Emilie Dionne, Simone Dahrouge, Catherine Spooner, Jeannie Haggerty, Jean-Frédéric Levesque, Mark Harris, and Grant Russell
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Program evaluation ,medicine.medical_specialty ,Knowledge management ,Psychological intervention ,Vulnerable populations ,Logic model ,Alberta ,Theory-based evaluation ,03 medical and health sciences ,0302 clinical medicine ,Health care ,medicine ,Humans ,030212 general & internal medicine ,Health policy ,Primary health care ,business.industry ,Unintended consequences ,Research ,030503 health policy & services ,Health Policy ,Public health ,Australia ,Public Health, Environmental and Occupational Health ,Health services research ,Equity ,Access ,3. Good health ,New South Wales ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,business ,Psychology - Abstract
Background Inequitable access to primary health care (PHC) remains a problem for most western countries. Failure to scale up effective interventions has been due, in part, to a failure to share the logic and essential elements of successful programs. The aim of this paper is to describe what we learned about improving access to PHC for vulnerable groups across multiple sites through use of a common theory-based program logic model and a common evaluation approach. This was the IMPACT initiative. Methods IMPACT’s evaluation used a mixed methods design with longitudinal (pre and post) analysis of six interventions. The analysis for this paper included four of the six sites that met study criteria. These sites were located in Canada (Alberta, Quebec and Ontario) and Australia (New South Wales). Using the overarching logic model, unexpected findings were reviewed, and alternative explanations were considered to understand how the mechanisms of each intervention may have contributed to results. Results Each site addressed their local access problem with different strategies and from different starting points. All sites observed changes in patient abilities to access PHC and provider access capabilities. The combination of intended and observed consequences for consumers and providers was different at each site, but all sites achieved change in both consumer ability and provider capability, even in interventions where there was no activity targeting provider behaviors. Discussion The model helped to identify, explore and synthesize intended and unintended consequences of four interventions that appeared to have more differences than similarities. Similar outcomes for different interventions and multiple impacts of each intervention on abilities were observed, implying complex causal pathways. Conclusions All the interventions were a low-cost incremental attempt to address unmet health care needs of vulnerable populations. Change is possible; sustaining change may be more challenging. Access to PHC requires attention to both patient abilities and provider characteristics. The logic model proved to be a valuable heuristic tool for defining the objectives of the interventions, evaluating their impacts, and learning from the comparison of ‘cases’.
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- 2021
8. Current and future transcatheter aortic valve replacement valves
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Ricky Muller Moran, Rachel Eikelboom, Michael J. Reardon, Michael H. Yamashita, Weiang Yan, Apurva Patel, and Aaron Spooner
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medicine.medical_specialty ,Transcatheter aortic ,business.industry ,medicine.medical_treatment ,Aortic Valve Stenosis ,Prosthesis Design ,medicine.disease ,Transcatheter Aortic Valve Replacement ,Stenosis ,Treatment Outcome ,Valve replacement ,Preclinical testing ,Aortic Valve ,Heart Valve Prosthesis ,medicine ,Humans ,Cardiology and Cardiovascular Medicine ,Intensive care medicine ,business ,Retrospective Studies ,Edwards sapien - Abstract
Purpose of review This review analyzes currently available commercial transcatheter aortic valve replacement (TAVR) valves as well as valves in investigational status and those in preclinical testing. The design features and clinical outcomes of the Edwards SAPIEN S3 and Medtronic Evolut PRO+ are described and compared with highlight clinical circumstances where one may be favoured over the other. Recent findings Multiple randomized and nonrandomized trials have compared commercial and investigational TAVR valves. The results of these are summarized and discussed within this review with a focus on how the SAPIEN S3 and Evolut PRO+ both compare to each other as well as various valves in different investigational stages. Summary TAVR is an innovative and ground-breaking technology that will forever have revolutionized the management of aortic stenosis. Though the technology and valves themselves have come a long way, further developments are necessary if we are to continue to expand its indications and achieve a safer perioperative experience with more durable valves.
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- 2021
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9. PatientLink: a patient-centred status dashboard for the perioperative process
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Lucie Spooner, Keesha Khehra, Christopher Nguan, Angela Cho, Elizabeth Burden, and Rohit Singla
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Process (engineering) ,business.industry ,Dashboard (business) ,Medicine ,General Medicine ,Medical emergency ,Perioperative ,business ,medicine.disease ,Patient centred - Published
- 2021
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10. Commentary: An all-access pass to transcatheter aortic valve replacement
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Hellmuth R. Muller Moran, Michael H. Yamashita, and Aaron Spooner
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Text mining ,Transcatheter aortic ,Valve replacement ,business.industry ,medicine.medical_treatment ,MEDLINE ,Medicine ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Published
- 2023
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11. Stress-induced aberrations in sensory processing predict worse cognitive outcomes in healthy aging adults
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Brittany K. Taylor, Howard S. Fox, Brenda Morsey, Pamela E. May, Tony W. Wilson, Rachel K. Spooner, Trey Ideker, Emma L'Heureux, Yasra Arif, Mikki Schantell, and Tina Wang
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Adult ,Male ,magnetoencephalography ,Aging ,Sensory processing ,medicine.medical_treatment ,Stimulation ,Gating ,Somatosensory system ,somatosensory ,Healthy Aging ,Young Adult ,Cognition ,Stress, Physiological ,medicine ,Humans ,Aged ,DNA methylation ,Sensory gating ,medicine.diagnostic_test ,business.industry ,Cell Biology ,Magnetoencephalography ,Middle Aged ,Sensory Gating ,Electric Stimulation ,Allostatic load ,neuropsychological assessment ,medicine.anatomical_structure ,Female ,business ,Neuroscience ,allostatic load ,Research Paper - Abstract
It is well recognized that not all individuals age equivalently, with functional dependence attributable, at least in part, to stress accumulated across the lifespan. Amongst these dependencies are age-related declines in cognitive function, which may be the result of impaired inhibitory processing (e.g., sensory gating). Herein, we examined the unique roles of life and biological stress on somatosensory gating dynamics in 74 adults (22-72 years old). Participants completed a sensory gating paired-pulse electrical stimulation paradigm of the right median nerve during magnetoencephalography (MEG) and data were subjected to advanced oscillatory and time-domain analysis methods. We observed separable mechanisms by which increasing levels of life and biological stress predicted higher oscillatory gating ratios, indicative of age-related impairments in inhibitory function. Specifically, elevations in life stress significantly modulated the neural response to the first stimulation in the pair, while elevations in biological stress significantly modulated the neural response to the second stimulation in the pair. In contrast, neither elevations in life nor biological stress significantly predicted the gating of time-domain neural activity in the somatosensory cortex. Finally, our study is the first to link stress-induced decline in sensory gating to cognitive dysfunction, suggesting that gating paradigms may hold promise for detecting discrepant functional trajectories in age-related pathologies in the future.
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- 2021
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12. Twelve-Month Outcomes of the AFFINITY Trial of Fluoxetine for Functional Recovery After Acute Stroke: AFFINITY Trial Steering Committee on Behalf of the AFFINITY Trial Collaboration
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Graeme J. Hankey, Maree L. Hackett, Osvaldo P. Almeida, Leon Flicker, Gillian E. Mead, Martin S. Dennis, Christopher Etherton-Beer, Andrew H. Ford, Laurent Billot, Stephen Jan, Thomas Lung, Erik Lundström, Katharina S. Sunnerhagen, Craig S. Anderson, Huy Thang-Nguyen, John Gommans, Qilong Yi, Veronica Murray, Robert Herbert, Gregory Carter, Geoffrey A. Donnan, Huy-Thang Nguyen, Qiang Li, Severine Bompoint, Sarah Barrett, Anne Claxton, Julia O’Dea, Michelle Tang, Clare Williams, Shenae Peterson, Christie Drummond, Uyen-Ha Hong, Linh-Thi My Le, Tram-Thi Bich Ngo, Yen-Bao Mai, Huyen-Thanh Han, Nhu-Quynh Truong, Huong-Thi Nguyen, Hai-Thanh Ngo, Thi Binh Nguyen, Oanh-Thi Kieu Ha, Trang-Le Huyen Nguyen, Richard I. Lindley, Peter New, Andrew Lee, Thanh-Trung Tran, Loan-Tran Truc Mai Le, Thuy-Le Vu Kieu, Sang-Van Nguyen, Thuy-Anh Diem Nguyen, Tam-Nhat Dang, Hanh-Thi Truc Phan, Loan-Thi Ngoc Vo, Mai-Hue Nguyen, Hanh-Cao Dang, Hong-Thi Tran, Linh-Thi Cam Dam, Trinh-Thi Kim Ngo, Thai-Nguyen Thanh Pham, Binh-Nguyen Pham, Nha-Thi Thanh Dao, Huong-Thi Bich Nguyen, Linh-Thi Cam Le, Chi-Minh Do, Huy-Quoc Huynh, Giau-Thi Kim Tran, Oanh-Thi Le, Ly-Thi Khanh Tran, Chinh-Dinh Duong, Duong-Van Kieu, Na Le, Hoa-Ngoc Nguyen, Binh-Van Le, Long-Thanh Nguyen, Long-Van Nguyen, Tuan-Quoc Dinh, Tan-Van Vo, Tram-Ngoc Bui, Uyen-Thi To Hoang, Hien-Thi Bich Nguyen, Ha-Thi Thu Nguyen, Nga-Thuy Lam, Khanh-Kim Le, Phuong-Thanh Trinh, Hop-Quang Huynh, Thao-Thi Thu Nguyen, Huyen-Ngoc Lu, Tham-Hong Pham, Sam-Hoanh Nguyen, Ninh-Hong Le, Giang-Truong Nguyen, Bich-Thi Doan, Sung-Phuoc Pham, Duong-Huu Luong, Ha-Van Mai, Thuc-Van Tran, Phuong-Thi Do, Hoai-Thi Le, Chi-Van Nguyen, Phuong-Doan Nguyen, Ton-Duy Mai, Phuong-Viet Dao, Dung-Tien Nguyen, Dai-Quoc Khuong, Trung-Xuan Vuong, Lan-Tuong Vu, Ngoc-Duc Ngo, Hanh-Hong Dang, Phuong-Thai Truong, Ngan-Thi Le, Hoa-Van Hoang, Chung-Quang Do, Minh-Thao Nguyen, Anh-Hai Dam, Quynh-Nhu Le, Ngoc-Hoang Nguyen, Tuyen-Van Nguyen, Toan-Dinh Le, Ha-Thi Hai Dinh, Cuong–Van Pham, Khanh-Thi Ngoc Thach, Linh-Hai Nguyen, Loan-Thi Nguyen, Vien-Chi Le, Phuong-Hong Tran, Tai-Anh Nguyen, Tuan-Van Le, Luyen-Van Truong, Tue-Chau Bui, Ngoc-Xuan Huynh, Lap-Van Dinh, An-Gia Pham, Trang-Thi Huyen Le, Vy-Tuong Nguyen, Yen-Hai Nguyen, Thang-Ba Nguyen, Huy Thai, Quyen-Thi Ngoc Pham, Khoa-Duy Dao, Quoc-Nguyen Bao Pham, Thuong-Thi Huyen Dang, Huong-Huynh To Dinh, Trang-Mai Tong, Thuy-Thi Vu, Si-Tri Le, Tai-Ngoc Tran, Phuong-Hoai Tran, Ngoc-Thuy Nhu Dinh, Binh-Thanh Nguyen, Vinh-Phuong Do, Anh-Ngoc Nguyen, Binh-Thi Thanh Nguyen, David Blacker, Lindsey Bunce, Ai Ling Tan, Darshan Ghia, Gillian Edmonds, Nicole O’Loughlin, Megan Ewing, Kerri-Ann Whittaker, Lorralee Deane, Yash Gawarikar, Brett Jones, Maria Lopez, Koushik Nagesh, Emma Siracusa, Stephen Davis, Amy McDonald, Jess Tsoleridis, Rachael McCoy, David Jackson, Gab Silver, Timothy R. Bates, Amanda Boudville, Lynda Southwell, Dennis Cordato, Alan J. McDougall, Cecilia Cappelen-Smith, Zeljka Calic, Shabeel Askar, Qi Cheng, Raymond Kumar, Richard Geraghty, Maree Duroux, Megan Ratcliffe, Samantha Shone, Cassandra McLennan, Ramesh Sahathevan, Casey Hair, Stanley Levy, Beverley Macdonald, Benjamin Nham, Louise Rigney, Dev Nathani, Sumana Gopinath, Vishal Patel, Abul Mamun, Benjamin Trewin, Chun Phua, Ho Choong, Lauren Tarrant, Kerry Boyle, Luisa Hewitt, Monique Hourn, Amanda Masterson, Kim Oakley, Karen Ruddell, Colette Sanctuary, Kimberley Veitch, Camelia Burdusel, Lina Lee, Gary Cheuk, Jeremy Christley, Tabitha Hartwell, Craig Davenport, Kate Hickey, Rosanna Robertson, Michelle Carr, Sam Akbari, Hannah Coyle, Megan O’Neill, Cameron Redpath, Caroline Roberts, Marjan Tabesh, Toni Withiel, Kapila Abeysuriya, Andrew Granger, Angela Abraham, Chermaine Chua, Dung Do Nguyen, Vathani Surendran, Melissa Daines, David Shivlal, Mudassar Latif, Noreen Mughal, Patricia Morgan, Martin Krause, Miriam Priglinger, Ehsan E. Shandiz, Susan Day, Lay Kho, Michael Pollack, Judith Dunne, Helen Baines, Merridie Rees, Jenni White, Aicuratiya Withanage, Candice Delcourt, Cheryl Carcel, Alejandra Malavera, Amy Kunchok, Elizabeth Ray, Elizabeth Pepper, Emily Duckett, Sally Ormond, Andrew Moey, Timothy Kleinig, Vanessa Maxwell, Chantal Baldwin, Wilson Vallat, Deborah Field, Romesh Markus, Kirsty Page, Danielle Wheelwright, Sam Bolitho, Steven Faux, Fix Sangvatanakul, Alexis Brown, Susan Walker, Jennifer Massey, Hillary Hayes, Pesi Katrak, Annie Winker, Alessandro Zagami, Alanah Bailey, Sarah Mccormack, Andrew Murray, Mark Rollason, Christopher Taylor, Fintan O’Rourke, Ye Min Kuang, Heike Burnet, Yvonne Liu, Aileen Wu, Diana Ramirez, Tissa Wijeratne, Sherisse Celestino, Essie Low, Cynthia Chen, Jennifer Bergqvist, Andrew Evans, Queenie Leung, Martin Jude, Rachael McQueen, Katherine Mohr, Latitia Kernaghan, Paul Stockle, Boon L. Tan, Sara Laubscher, Diana Schmid, Melissa Spooner, Bhavesh Lallu, Bronwen Pepperell, John Chalissery, Karim Mahawish, Susan DeCaigney, Paula Broughton, Karen Knight, Veronica Duque, Harry McNaughton, Jeremy Lanford, Vivian Fu, and Lai-Kin Wong
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Male ,medicine.medical_specialty ,Steering committee ,medicine.medical_treatment ,Placebo ,B700 ,Fractures, Bone ,Cognition ,Double-Blind Method ,Recurrence ,Seizures ,Fluoxetine ,Internal medicine ,Humans ,Medicine ,Stroke ,Fatigue ,Aged ,Ischemic Stroke ,Acute stroke ,Advanced and Specialized Nursing ,business.industry ,Recovery of Function ,Middle Aged ,Functional recovery ,medicine.disease ,Clinical trial ,Affect ,Hemorrhagic Stroke ,Quality of Life ,Accidental Falls ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,Stroke recovery ,Selective Serotonin Reuptake Inhibitors ,medicine.drug - Abstract
Background and Purpose: The AFFINITY trial (Assessment of Fluoxetine in Stroke Recovery) reported that oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and seizures. After trial medication was ceased at 6 months, survivors were followed to 12 months post-randomization. This preplanned secondary analysis aimed to determine any sustained or delayed effects of fluoxetine at 12 months post-randomization. Methods: AFFINITY was a randomized, parallel-group, double-blind, placebo-controlled trial in adults (n=1280) with a clinical diagnosis of stroke in the previous 2 to 15 days and persisting neurological deficit who were recruited at 43 hospital stroke units in Australia (n=29), New Zealand (4), and Vietnam (10) between 2013 and 2019. Participants were randomized to oral fluoxetine 20 mg once daily (n=642) or matching placebo (n=638) for 6 months and followed until 12 months after randomization. The primary outcome was function, measured by the modified Rankin Scale, at 6 months. Secondary outcomes for these analyses included measures of the modified Rankin Scale, mood, cognition, overall health status, fatigue, health-related quality of life, and safety at 12 months. Results: Adherence to trial medication was for a mean 167 (SD 48) days and similar between randomized groups. At 12 months, the distribution of modified Rankin Scale categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio, 0.93 [95% CI, 0.76–1.14]; P =0.46). Compared with placebo, patients allocated fluoxetine had fewer recurrent ischemic strokes (14 [2.18%] versus 29 [4.55%]; P =0.02), and no longer had significantly more falls (27 [4.21%] versus 15 [2.35%]; P =0.08), bone fractures (23 [3.58%] versus 11 [1.72%]; P =0.05), or seizures (11 [1.71%] versus 8 [1.25%]; P =0.64) at 12 months. Conclusions: Fluoxetine 20 mg daily for 6 months after acute stroke had no delayed or sustained effect on functional outcome, falls, bone fractures, or seizures at 12 months poststroke. The lower rate of recurrent ischemic stroke in the fluoxetine group is most likely a chance finding. Registration: URL: http://www.anzctr.org.au/ ; Unique identifier: ACTRN12611000774921.
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- 2021
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13. Observation of the reactions between iron ore and metallurgical fluxes for the alternative ironmaking HIsarna process
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Zushu Li, Stephen Spooner, Koen Meijer, and James Whiston
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Basic oxygen steelmaking ,business.industry ,Mechanical Engineering ,TN ,Metallurgy ,Metals and Alloys ,Slag ,engineering.material ,TS ,Steelmaking ,law.invention ,Iron ore ,Mechanics of Materials ,law ,Scientific method ,visual_art ,Materials Chemistry ,visual_art.visual_art_medium ,engineering ,Environmental science ,QD ,Calcination ,business ,Lime - Abstract
This work investigates the melting behaviour of iron ore with calcium-based fluxes, including lime, limestone and basic oxygen furnace (BOF) steelmaking slag. With an aim to explore the potential kinetic benefits that can be obtained through the formation of a liquid medium on the overall productivity of HIsarna. A HT-CLSM was used to rapidly heat and observation the interface between a given pair of chosen materials in-situ. Through this method, the rate at which the reaction progressed and the possible disruptive phenomenon that may occur was observed directly. The molten interface of fluxed materials is compared against each other offering insight into relative dissolution rate. Each flux shows promise of increasing ore fluidity to a varying degree with limestone generating above a 60% liquid fraction in the 1400°C reaction temperature.\ud \ud
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- 2021
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14. Long-term Anti–Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration: The LATAR Study
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Kimberly Spooner, Andrew Chang, Long Phan, Samantha Fraser-Bell, James Wong, and Thomas Hong
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medicine.medical_specialty ,Visual acuity ,genetic structures ,Fundus (eye) ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Study report ,Ophthalmology ,medicine ,030304 developmental biology ,Anti vegf ,0303 health sciences ,business.industry ,Retrospective cohort study ,Macular degeneration ,medicine.disease ,eye diseases ,Vascular endothelial growth factor ,Choroidal neovascularization ,chemistry ,030221 ophthalmology & optometry ,sense organs ,medicine.symptom ,business - Abstract
Purpose To report the 10-year outcomes of eyes with neovascular age-related macular degeneration (nAMD) treated with vascular endothelial growth factor (VEGF) inhibitors. Design Ten-year, retrospective cohort study. Participants A total of 1046 patients who commenced treatment with anti-VEGF for nAMD. Methods Anti-VEGF–naive eyes diagnosed with nAMD that commenced treatment between November 2006 and December 2009 were identified. Data collected included the baseline demographics, visual acuity (VA), and number of intravitreal injections. Baseline fundus fluorescein angiograms and OCT images were graded for choroidal neovascularization type. OCT images were graded for central macular thickness (CMT) and the presence of fluid over the 10 years. Main Outcome Measures Change in vision at 10 years. Secondary outcomes included the proportion of eyes with 20/40 vision or better and 20/200 or worse, the proportion of eyes that were dry on OCT imaging, and the number of injections. Results Of 1046 eligible eyes, 10-year data were available for 293 (28%), which were included in the analyses. Eyes received 58.1 (standard deviation [SD], 33.6) injections during the 10 years. The mean CMT decreased from 355.5 μm (SD, 107.8 μm) to 264.2 (SD, 79.5) μm (P Conclusions On average, eyes with nAMD maintained starting VA when treated with VEGF inhibitors for 10 years. With ongoing regular treatment, a greater proportion of eyes achieved VA of 20/40 or better at 10 years than at presentation.
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- 2021
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15. Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer
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Q Davies, Anna Collins, Jonathan Horne, Mira Chainrai, Esther L. Moss, Rasiah Bharathan, Stephanie Spooner, Franscois Runau, Tim Bourne, and Supratik Chattopadhyay
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Cancer Research ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Blood Loss, Surgical ,law.invention ,Blood loss ,law ,Intensive care ,medicine ,Humans ,Blood Transfusion ,Perioperative Period ,Ovarian Neoplasms ,business.industry ,Cytoreduction Surgical Procedures ,General Medicine ,Bowel resection ,Perioperative ,Length of Stay ,Middle Aged ,medicine.disease ,Intensive care unit ,Intestines ,Intensive Care Units ,Oncology ,Emergency medicine ,Female ,Cytoreductive surgery ,business ,Ovarian cancer ,Risk assessment - Abstract
BACKGROUND Peri-operative variables associated with prolonged Intensive Care Unit (ICU) admission following cytoreductive surgery for ovarian cancer were investigated. PATIENTS AND METHODS A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ovarian cancer in a single tertiary referral centre from 2015-2019. Patients were categorized according to length of ICU stay (
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- 2021
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16. The characterization of key physiological traits of medicinal cannabis (Cannabis sativa L.) as a tool for precision breeding
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Renata M. Polotnianka, Melinda Quinn, Rebecca C. Baillie, Laura E. Spooner, Erez Naim-Feil, Amy Miner, German Spangenberg, Luke W. Pembleton, Noel O. I. Cogan, and Alix L. Malthouse
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0106 biological sciences ,0301 basic medicine ,Yield ,Flowering time ,Vegetative reproduction ,Plant Science ,01 natural sciences ,Crop ,Heritability ,03 medical and health sciences ,Quantitative Trait, Heritable ,Plant breeding ,Cultivar ,Selection ,Uncategorized ,Cannabis ,biology ,Correlations ,Growth rate ,business.industry ,Phenology ,Research ,fungi ,Botany ,Genetic Variation ,food and beverages ,biology.organism_classification ,Biotechnology ,Prediction equation ,Plant Breeding ,030104 developmental biology ,Phenotype ,Agriculture ,QK1-989 ,business ,010606 plant biology & botany - Abstract
BackgroundFor millennia, drug-type cannabis strains were extensively used for various medicinal, ritual, and inebriant applications. However, cannabis prohibition during the last century led to cultivation and breeding activities being conducted under clandestine conditions, while scientific development of the crop ceased. Recently, the potential of medicinal cannabis has been reacknowledged and the now expanding industry requires optimal and scientifically characterized varieties. However, scientific knowledge that can propel this advancement is sorely lacking. To address this issue, the current study aims to provide a better understanding of key physiological and phenological traits that can facilitate the breeding of advanced cultivars.ResultsA diverse population of 121 genotypes of high-THC or balanced THC-CBD ratio was cultivated under a controlled environment facility and 13 plant parameters were measured. No physiological association across genotypes attributed to the same vernacular classification was observed. Floral bud dry weight was found to be positively associated with plant height and stem diameter but not with days to maturation. Furthermore, the heritability of both plant height and days to maturation was relatively high, but for plant height it decreased during the vegetative growth phase. To advance breeding efficacy, a prediction equation for forecasting floral bud dry weight was generated, driven by parameters that can be detected during the vegetative growth phase solely.ConclusionsOur findings suggest that selection for taller and fast-growing genotypes is likely to lead to an increase in floral bud productivity. It was also found that the final plant height and stem diameter are determined by 5 independent factors that can be used to maximize productivity through cultivation adjustments. The proposed prediction equation can facilitate the selection of prolific genotypes without the completion of a full cultivation cycle. Future studies that will associate genome-wide variation with plants morphological traits and cannabinoid profile will enable precise and accelerated breeding through genomic selection approaches.
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- 2021
17. Henry Gewirtz, MD (1945-2021)
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Edwin L. Palmer, Stephen A. Abraham, James A. Scott, Amy E. Spooner, Michael J Osborne, Gerasimos D. Zervos, Ahmed Tawakol, and Shawn A. Gregory
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business.industry ,MEDLINE ,Medicine ,Library science ,Radiology, Nuclear Medicine and imaging ,Cardiology and Cardiovascular Medicine ,business - Published
- 2021
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18. Substance use, suicidality and sexual activity among secondary school adolescents from Bhutan and Nepal
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Kezang Sherab, Sagun Ballav Pant, Upadhyaya S, Catherine Spooner, Bihungum Bista, and John Howard
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medicine.medical_specialty ,biology ,business.industry ,030503 health policy & services ,Public health ,education ,Public Health, Environmental and Occupational Health ,biology.organism_classification ,Mental health ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Condom ,law ,Environmental health ,Epidemiology ,medicine ,Survey data collection ,030212 general & internal medicine ,Cannabis ,School health ,Substance use ,0305 other medical science ,business - Abstract
Alcohol, tobacco and cannabis use, early sexual debut and suicidality among young people are public health issues. This study sought to explore associations between health-risk behaviours (use of alcohol, tobacco and cannabis, mental health and suicidality) and protective factors among in-school Himalayan secondary students from Bhutan and Nepal. Secondary analyses of WHO Global School Health Survey data obtained from the cross-sectional surveys of in-school Himalayan secondary students from Bhutan (2016, n = 7576) and Nepal (2015, n = 6529). Findings showed a concerning level of suicidality in both countries, early commencement of alcohol use, higher prevalence of current cannabis and alcohol use in Bhutan, and low condom use overall. Preventive health activities that target students at younger ages, males in particular, need strengthening, as do risk reduction efforts to delay onset of substance use and sexual debut and strategies to increase protective factors such as retention and participation in education.
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- 2021
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19. Volume IV The DUNE far detector single-phase technology
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L. Di Giulio, J. Martin-Albo, S. Ravat, W. Mu, D. Marfatia, T. Kosc, D. Autiero, Poonam Mehta, A. Borkum, N. McConkey, G. Karagiorgi, Robert Wilson, L. M. Cremaldi, Stephen P. Gent, T. Young, Julián Félix, D. MacFarland, Andrew Smith, M. Manrique Plata, J. Freestone, D. Rivera, B. Stillwell, Marco Verzocchi, A. Lambert, Orlando L. G. Peres, K. Gollwitzer, E. Kemp, G. Yang, I. Kreslo, F. Varanini, M. Chalifour, A. Holin, S. J. Patton, R. J. Nichol, Giovanni Bellettini, V. A. Kudryavtsev, M. Sorel, E. Church, S. Kasai, H. O. Back, A. Lister, S. Santana, C. Mariani, Carlos Escobar, J. C. Freeman, Kaushik De, M. J. Rodriguez Alonso, M. A. Acero, A. Christensen, G. S. Varner, S. Sacerdoti, D. Shooltz, Seodong Shin, M. Santos-Maldonado, T. Schaffer, Jeremy Wolcott, J. Vasel, J. A. Gonzalez-Cuevas, J. Franc, C. Mossey, Jonas Rademacker, G. P. Zeller, Joshua Barrow, John Marshall, Alessandro Thea, H. A. Tanaka, W. C. Louis, E. Hazen, Armin Karcher, D. Smargianaki, Christopher L. Marshall, M. Soderberg, A. C. Weber, Christopher J. Milne, E. Brianne, A. Aranda-Fernandez, J. Calcutt, K. Warburton, M. Nalbandyan, Dave Sankey, J. Asaadi, F. Diaz, E. Valencia, B. Kirby, A. Bross, K. Koehler, M. A. Uchida, Y. Bezawada, D. Warner, C. E. Thorn, Srubabati Goswami, Z. Williams, Gregory Iles, A. Friedland, K. M. Heeger, V. P. Luzio, G. C. Blazey, J. Barranco Monarca, Carl Grace, A. M. Gago, E. James, M. Newcomer, H. W. Sobel, Roberto Gutiérrez, C. Vignoli, R. Hatcher, M. Zhao, F. Cavalier, M. A. Hernandez Morquecho, N. Poonthottathil, Ara Ioannisian, W. Metcalf, T. Wongjirad, H. T. Rakotondramanana, D. Cherdack, M. A. Ramirez Delgado, R. Diurba, G. Christodoulou, S. Calvez, T. Durkin, H. Y. Wei, M. Muether, S. Roy, A. Caminata, A. Scarpelli, Christopher Brew, Pavel Snopok, Y. Rigaut, L. Escudero Sanchez, K. Kothekar, W. Flanagan, V. Papadimitriou, S. J. Brice, Nicolas Lurkin, M. V. Diwan, Andrew White, S. Berkman, H. Muramatsu, Z. Pavlovic, A. A. Machado, Christian Farnese, A. Mastbaum, Alfredo G. Cocco, G. Zhu, S. Centro, S. Henry, J. Rout, P. de Jong, H. Carranza, Milos Lokajicek, K. Nishimura, A. Delbart, N. J. C. Spooner, C. McGrew, E. Pantic, Mario Campanelli, David Cussans, B. T. Fleming, K. Negishi, F. Spagliardi, J. Nesbit, André Rubbia, Akitaka Ariga, Marvin L Marshak, F. Pietropaolo, F. D. M. Blaszczyk, T. Hasegawa, Kate Scholberg, O. Gogota, R. Poling, Simon Jones, A. Tonazzo, M. P. Andrews, R. Petti, S. Bertolucci, M. Bonesini, A. F. Moor, C. Barnes, A. S. Hesam, S. H. Kettell, M. Bongrand, M. R. While, D. J. Payne, C. Gotti, A. Chiriacescu, Paul Keener, Leigh H. Whitehead, James Stewart, A. Mazzacane, L. W. Koerner, T. Rehak, C. Andreopoulos, F. Terranova, Jaroslaw Pasternak, E. Raguzin, L. C. J. Rice, J. L. Bazo Alba, S. Li, J. Hartnell, M. Potekhin, N. Moggi, D. J. Summers, J. Berger, L. Cremonesi, Katsuya Yonehara, T. E. Coan, Claire Shepherd-Themistocleous, B. Radics, Karol Hennessy, S. Söldner-Rembold, C. S. Lin, L. Greenler, B. Guo, Frank Filthaut, R. B. Patterson, E. Pennacchio, E. Zhivun, C. Cuesta, T. Loew, G. Prior, D. Duchesneau, Lina Necib, S. Rescia, W. Gu, Andrés Castillo, N. Kazaryan, O. G. Miranda, C. Patrick, Robert Shrock, José W. F. Valle, J. Reichenbacher, D. A. Sanders, John F. Beacom, S. Tufanli, S. Ventura, Riccardo Papaleo, J. Zennamo, A. De Roeck, M. Calin, P. Ding, Alessandro Menegolli, B. V. K. S. Potukuchi, T. Le, T. Wachala, L. O. Arnold, J. R. Macier, A. M. Teklu, E. Blucher, L. Hertel, F. W. Sippach, S. Childress, T. Miao, P. Fernandez Menendez, J. Han, R. Gandrajula, C. Y. Chi, Marzio Nessi, Aldo Penzo, Ina Sarcevic, Kendall Mahn, Jorge Molina, F. Bonini, Eric W. Hoppe, M. Groh, Barry King, R. Mazza, Keith Rielage, Patrick Dunne, M. Mellinato, D. Lorca, R. Guenette, F. Bento Neves, L. Pickering, Manuel Alejandro Segura Delgado, J. J. Russell, H. R. Gallagher, J. Zuklin, Steven Gardiner, P. Madigan, D. Douglas, Daniel Gastler, S. Manly, P. Hamilton, L. Montaño Zetina, R. G. Van de Water, S. Dennis, M. Tenti, N. Dokania, Kim Siyeon, E. Fernandez-Martinez, P. P. Koller, D. Whittington, T. Li, M. C. Sanchez, S. Biagi, C. Sarasty, Juraj Bracinik, A. N. Khotjantsev, N. Tsverava, Yasaman Farzan, M. Tzanov, J. G. Boissevain, J. Smolik, Andrew Brandt, J. Hoff, D. A. Harris, C. Distefano, Ornella Palamara, H. S. Budd, Alastair Grant, A. K. Giri, Thorsten Lux, C. E. Lane, J. Marteau, Irakli Lomidze, E. Kearns, Zviad Tsamalaidze, L. S. Gomez Fajardo, H. da Motta, J. S. Real, Sukalyan Chattopadhyay, B. Viren, J. Mousseau, Ihn Sik Seong, C. M. Sutera, A. C. Ezeribe, F. Ferraro, Marco Adinolfi, Nikolaos Simos, A. Stuart, D. Brailsford, N. Solomey, Laura Manenti, L. V. Gomez Bermeo, Andrea Zani, Kristian Harder, Timothy M. Shaw, J. Hewes, Sandro Palestini, D. Braga, D. Garcia-Gamez, J. Stock, S. Bolognesi, D. Belver, Laura Paulucci, J. Ahmed, Narendra Sahu, Sandip Pakvasa, L. Pasqualini, D. Mladenov, M. Kordosky, S. Zucchelli, L. Stanco, M. Torti, B. Jargowsky, E. Smith, C. J. Solano Salinas, N.V. Mokhov, D. Vanegas Forero, C. Jesús-Valls, Andrew Blake, L. Jiang, F. Andrianala, W. Ketchum, Matthaeus Leitner, K. Fahey, Marco Pallavicini, Bindu A. Bambah, K. Francis, M. H. Shaevitz, N. Barros, I. Caro Terrazas, R. Itay, G. Sirri, H. Steiner, Laura Dominé, S. Lockwitz, G. Savage, N. Bostan, J. A. Nowak, A. Scarff, Konstantinos Manolopoulos, R. K. Plunkett, B. Morgan, A. Rafique, Cari L. Johnson, M. Parvu, L. Patrizii, James A. Anderson, L. Corwin, A. Hourlier, S. L. Mufson, S. Martynenko, V. J. Guarino, B. Carlus, D. Boyden, F. Marinho, David Delepine, J. Bremer, Paola Sala, P. Cotte, J.V. Dawson, G. Mandrioli, O. Goodwin, Jitendra Kumar, Ph. Lebrun, J. Soto-Oton, K. K. Guthikonda, Evgueni Goudzovski, Gabriella Carini, S. Gao, M. Dabrowski, Sudarshan Paramesvaran, G. Pessina, S. Davini, R. L. Talaga, Francesco Gonnella, A. Joglekar, G. Sinev, S. Gwon, A. Surdo, M. O. Wascko, R. Bajou, Pedro A. N. Machado, Massimo Rossella, G. S. Davies, I. De Bonis, K. S. McFarland, C. T. Macias, T. Alion, O. V. Mineev, M. Bishai, R. Northrop, Chao Zhang, R. Van Berg, L. Di Noto, Kam-Biu Luk, J. Chaves, J. Wang, K. Qi, W. E. Sondheim, Sergei Striganov, B. Paulos, Janice L. Thompson, M. Rai, P. N. Ratoff, T. Kutter, D. Totani, J. A. B. Coelho, F. Stocker, T. Gamble, J. J. Grudzinski, I. Gil-Botella, T. Yang, Wayne A. Barkhouse, C. E. Tull, H. Mendez, Z. Ghorbani-Moghaddam, Y.-J. Jwa, F. Cavanna, F. Kamiya, V. Basque, R. Sipos, V. Bellini, C. Alt, Sandhya Choubey, B. Abi, A. Mefodiev, V. A. Kostelecky, A. L. Renshaw, Giuseppe Benedetto Cerati, S. Balasubramanian, M. Biassoni, D. Pershey, J. Maricic, K. Lande, A. Muir, L.S. Rochester, A. Papanestis, A. Aurisano, F. Bay, R. Nandakumar, T. L. Usher, Bo Yu, A. V. Waldron, A. Filkins, Y. Cui, P. A. Rodrigues, Daijin Kim, G.D. Barr, Junwei Huang, V. De Romeri, H.E. Rogers, Andrea Dell'Acqua, A. Cervera Villanueva, Robert Svoboda, Yu. Onishchuk, T. Hamernik, A. P. Furmanski, M. Wetstein, P.T. Smith, G. Brunetti, Mariam Tórtola, Matthew L Strait, G. Barenboim, P. Guzowski, J. D. Eisch, N. Gallice, D. Newhart, A. J. Roeth, H. Berns, E. Granados, A. Weinstein, A. Falcone, D. Caratelli, L. Bellantoni, Wei Wu, J. Mills, A. Hackenburg, D. Caiulo, Chia-Chan Chang, Dave M Newbold, C. K. Jung, F. Krennrich, G. Testera, S. Rosauro-Alcaraz, A. Sitraka, L. Bagby, J. M. LoSecco, S. Tariq, C. Mauger, J. J. Back, J. Yu, R. Acciarri, B. Behera, P. Lasorak, Karol Lang, Irina Mocioiu, H. Schellman, Han Wang, Sergey A. Kulagin, A. Bashyal, Beatriz B. Siffert, C. N. Booth, L. Zambelli, M. T. Graham, A. Mann, Rakesh Kumar, Y. Xiao, Gregory J Pawloski, T. Prakash, Arsen Khvedelidze, A.S. Dyshkant, Paolo Carniti, C. Rubbia, M. Reggiani-Guzzo, M. M. Khabibullin, D. Wenman, S. C. Timm, R. Sharma, R. Saakyan, Marcelo M. Guzzo, P. Baesso, M. Pozzato, T. R. Junk, C. Morris, A. Cervelli, A. Heavey, Grzegorz Deptuch, M. Á. García-Peris, B. Bhuyan, M. Kabirnezhad, Pierre Baldi, M. Mooney, E. Tyley, A. Hahn, V. Susic, S. D. Reitzner, M. P. Decowski, V. Galymov, E. Chardonnet, B. R. Littlejohn, B. Ramson, B. Russell, M. Vagins, L. Fields, V. Zutshi, Sandeep Miryala, Enrique Calvo, V. Radeka, P. Debbins, J. Sinclair, B. Bilki, C. Touramanis, J. I. Crespo-Anadón, J. M. Paley, Antonio Ereditato, N. Yershov, C. J. Densham, D. W. Schmitz, A. Gallego-Ros, N. Buchanan, N. Mauri, A. Lawrence, K. Cho, S. Narita, X. Luo, A. Booth, D. A. Dwyer, S. Prince, J. Haiston, Jianbei Liu, T. J. Langford, E. Gamberini, Matheus Hostert, Dario Gnani, P. Vahle, G. A. Horton-Smith, A. Marchionni, I. K. Furic, John Matthews, K. Mason, M. Bhattacharjee, Randall P. Johnson, Amelia Maio, E. Motuk, C. Castromonte, Paolo Calafiura, Q. David, T. Miedema, S. Magill, Z. Ahmad, John Evans, Yi Chen, E. Ewart, S. Gollapinni, K. V. Tsang, J. Maneira, R.A. Rameika, A. de Gouvea, M. A. Vermeulen, R. M. Berner, J. J. De Vries, S. Shafaq, L. Da Silva Peres, A. McNab, G. Vasseur, A. Verdugo, C. Petta, Kenneth Long, H. S. Chen, K. Mavrokoridis, M. J. Dolinski, Yu. Kudenko, D. Gratieri, Alexandru Jipa, J. R. T. de Mello Neto, Olga Beltramello, J. T. Haigh, B. Gelli, Gregory J. Michna, A. M. Iliescu, Alex Reynolds, K. Biery, Yanchu Wang, V. Aushev, J. Zalesak, L. Simard, Ionel Lazanu, L. Pagani, J. Rodriguez Rondon, Alec Habig, M. Nebot-Guinot, R. Illingworth, G. Petrillo, J. S. Díaz, P. Novella, K. Grzelak, A. Gendotti, A. Himmel, M. Rajaoalisoa, P. Bour, L. Mualem, D. Pugnere, E. Niner, C. A. Moura, A. D. Marino, S. Bordoni, James Mueller, W. Fox, Jordan Ott, Niki Saoulidou, M. Oberling, E. Mazzucato, Silvia Pascoli, K. Herner, Hem Raj Sharma, M. Betancourt, T. Lord, L. Zazueta, Alexander Deisting, B. Rebel, Joleen Pater, David H. Adams, I. L. De Icaza Astiz, Stefan Antusch, M. Worcester, A. Higuera Pichardo, C. Kuruppu, Janet Conrad, Z. Parsa, Francesco Tortorici, L. Suter, J. Moon, P. E. L. Clarke, C. Palomares, Sofia Andringa, F. Jediny, J. Urheim, D. Montanari, Giorgio Riccobene, A. Rappoldi, J. Migenda, S. Matsuno, Y. Karyotakis, Jürgen Pozimski, Artur M. Ankowski, D. Edmunds, T. Safford, E. Tatar, Utku Kose, Z. Djurcic, D. Vargas, C. Wret, F. Sergiampietri, Rex Tayloe, F. Barao, I. Rakhno, Rukmani Mohanta, Andrew Norman, V. N. Solovov, X. Pons, V. Paolone, V. Pec, J. Pillow, S. Vergani, V. Savinov, P. Melas, Simon Lin, K. Wood, E. D. Zimmerman, M. A. Leigui de Oliveira, A. Olivier, Kevin J. Kelly, D. Sgalaberna, M. Gold, M. Spanu, Xiaolu Ji, A. M. Szelc, Gareth J. Barker, C. Cattadori, J. Fowler, S. J. M. Peeters, Raj Gandhi, M. Masud, R. LaZur, C. Grant, A. Olivares Del Campo, Joshua R. Klein, Vasundhara Singh, Ranjan Dharmapalan, Lynn Wood, E. Bechetoille, Patrick Green, Gustaaf Brooijmans, R. Howell, K. Moffat, J. G. Learned, J. Spitz, E. McCluskey, T. Patzak, M. D. Messier, J. A. Musser, R. Raboanary, P. Schlabach, C. Lastoria, D. Naples, Kazuhiro Terao, A. Paudel, Michael Mulhearn, S. B. Boyd, T. Hill, G. A. Valdiviesso, S. Emery, M. C. Goodman, D. C. Christian, S. Alonso Monsalve, B. Howard, G. Ge, Alexander Tapper, Thomas Strauss, J. Hugon, M. Kirby, K. Zeug, A. Laundrie, B. Szczerbinska, R. Flight, H. Vieira de Souza, D. M. DeMuth, A. Chatterjee, S. Kohn, F. Drielsma, A. Bitadze, B. Zamorano, Warner A. Miller, Yichen Li, Wladyslaw Henryk Trzaska, F. Piastra, C. Wilkinson, M. Greenwood, C. Girerd, R.J. Staley, R. Cross, S. Di Domizio, G. Meng, A. Mislivec, A. Sousa, K. Spurgeon, R. Gran, M. Roda, G.L. Raselli, R. S. Fitzpatrick, L. Rakotondravohitra, A. C. Kaboth, Matthew Mewes, Kai Loo, J. Trevor, T. Vrba, S. P. Kasetti, Y. Penichot, M. J. Wilking, M. Zito, S. Pordes, P. Weatherly, James John Brooke, M. Wallbank, F. F. Wilson, Nektarios Benekos, Renato Potenza, M. Toups, H. Y. Liao, Haleh Khani Hadavand, D. Redondo, S. R. Mishra, R. A. Gomes, E. Gramellini, S. Menary, P. C. de Holanda, D. Gibin, M. Stancari, B. J. P. Jones, C. Vilela, B. Tapia Oregui, N. Nayak, Sofia Vallecorsa, K. E. Duffy, E. Segreto, Xin Qian, T. A. Mohayai, Olga Mena, N. Martinez, O.V. Dvornikov, Filippo Resnati, M. B. Smy, K. Soustruznik, Diana Navas-Nicolas, S. Jiménez, R. Zwaska, William J. Marciano, C. Hohl, R. Haenni, Piera Sapienza, M. Shamma, N. P. Samios, H. Duyang, G. Lehmann Miotto, H. Meyer, A. Schukraft, C. S. Mishra, Vlastimil Kus, S. Murphy, Jianming Bian, C. Backhouse, Stephen J. Parke, J. Perry, Stephen Hillier, A. Guglielmi, D. Franco, M. Soares Nunes, A. Maddalena, M. Antonova, T. Boschi, J. L. Raaf, J. Singh, Alan Watson, F. Muheim, R. Milincic, P. Bernardini, Ralf Lehnert, T. A. Bolton, J. Greer, Y. T. Tsai, Mafalda Dias, L. Camilleri, S. Nagu, J. A. Maloney, Z. Vallari, J. Sensenig, I. Kadenko, D. Waters, S. Prakash, D. Ruterbories, Antonino Sergi, L. Kashur, M. Eads, C. Montanari, E. Conley, A. Scaramelli, S. Fuess, E. Cristaldo, H. Razafinime, Alessandro Montanari, T. Stokes, L. Li, Marc Weber, C. Bromberg, M. Leyton, M. E. Convery, S. Green, Jack Fried, P. De Lurgio, George Adamov, C. A. Ternes, Jane Nachtman, Y. A. Ramachers, D. A. Martinez Caicedo, E. T. Worcester, R. M. de Almeida, Yasar Onel, Mingshui Chen, A. Izmaylov, Claudia Brizzolari, C. Griffith, J. K. Nelson, K. Vaziri, M. A. Arroyave, F. Azfar, M. Karolak, Deywis Moreno, L. Molina Bueno, Science and Technology Facilities Council (STFC), Abi, B, Acciarri, R, Acero, M, Adamov, G, Adams, D, Adinolfi, M, Ahmad, Z, Ahmed, J, Alion, T, Monsalve, S, Alt, C, Anderson, J, Andreopoulos, C, Andrews, M, Andrianala, F, Andringa, S, Ankowski, A, Antonova, M, Antusch, S, Aranda-Fernandez, A, Ariga, A, Arnold, L, Arroyave, M, Asaadi, J, Aurisano, A, Aushev, V, Autiero, D, Azfar, F, Back, H, Back, J, Backhouse, C, Baesso, P, Bagby, L, Bajou, R, Balasubramanian, S, Baldi, P, Bambah, B, Barao, F, Barenboim, G, Barker, G, Barkhouse, W, Barnes, C, Barr, G, Monarca, J, Barros, N, Barrow, J, Bashyal, A, Basque, V, Bay, F, Alba, J, Beacom, J, Bechetoille, E, Behera, B, Bellantoni, L, Bellettini, G, Bellini, V, Beltramello, O, Belver, D, Benekos, N, Neves, F, Berger, J, Berkman, S, Bernardini, P, Berner, R, Berns, H, Bertolucci, S, Betancourt, M, Bezawada, Y, Bhattacharjee, M, Bhuyan, B, Biagi, S, Bian, J, Biassoni, M, Biery, K, Bilki, B, Bishai, M, Bitadze, A, Blake, A, Siffert, B, Blaszczyk, F, Blazey, G, Blucher, E, Boissevain, J, Bolognesi, S, Bolton, T, Bonesini, M, Bongrand, M, Bonini, F, Booth, A, Booth, C, Bordoni, S, Borkum, A, Boschi, T, Bostan, N, Bour, P, Boyd, S, Boyden, D, Bracinik, J, Braga, D, Brailsford, D, Brandt, A, Bremer, J, Brew, C, Brianne, E, Brice, S, Brizzolari, C, Bromberg, C, Brooijmans, G, Brooke, J, Bross, A, Brunetti, G, Buchanan, N, Budd, H, Caiulo, D, Calafiura, P, Calcutt, J, Calin, M, Calvez, S, Calvo, E, Camilleri, L, Caminata, A, Campanelli, M, Caratelli, D, Carini, G, Carlus, B, Carniti, P, Terrazas, I, Carranza, H, Castillo, A, Castromonte, C, Cattadori, C, Cavalier, F, Cavanna, F, Centro, S, Cerati, G, Cervelli, A, Villanueva, A, Chalifour, M, Chang, C, Chardonnet, E, Chatterjee, A, Chattopadhyay, S, Chaves, J, Chen, H, Chen, M, Chen, Y, Cherdack, D, Chi, C, Childress, S, Chiriacescu, A, Cho, K, Choubey, S, Christensen, A, Christian, D, Christodoulou, G, Church, E, Clarke, P, Coan, T, Cocco, A, Coelho, J, Conley, E, Conrad, J, Convery, M, Corwin, L, Cotte, P, Cremaldi, L, Cremonesi, L, Crespo-Anadon, J, Cristaldo, E, Cross, R, Cuesta, C, Cui, Y, Cussans, D, Dabrowski, M, Motta, H, Peres, L, David, Q, Davies, G, Davini, S, Dawson, J, De, K, Almeida, R, Debbins, P, Bonis, I, Decowski, M, Gouvea, A, Holanda, P, Astiz, I, Deisting, A, Jong, P, Delbart, A, Delepine, D, Delgado, M, Dell'Acqua, A, Lurgio, P, Neto, J, Demuth, D, Dennis, S, Densham, C, Deptuch, G, Roeck, A, Romeri, V, Vries, J, Dharmapalan, R, Dias, M, Diaz, F, Diaz, J, Domizio, S, Giulio, L, Ding, P, Noto, L, Distefano, C, Diurba, R, Diwan, M, Djurcic, Z, Dokania, N, Dolinski, M, Domine, L, Douglas, D, Drielsma, F, Duchesneau, D, Duffy, K, Dunne, P, Durkin, T, Duyang, H, Dvornikov, O, Dwyer, D, Dyshkant, A, Eads, M, Edmunds, D, Eisch, J, Emery, S, Ereditato, A, Escobar, C, Sanchez, L, Evans, J, Ewart, E, Ezeribe, A, Fahey, K, Falcone, A, Farnese, C, Farzan, Y, Felix, J, Fernandez-Martinez, E, Menendez, P, Ferraro, F, Fields, L, Filkins, A, Filthaut, F, Fitzpatrick, R, Flanagan, W, Fleming, B, Flight, R, Fowler, J, Fox, W, Franc, J, Francis, K, Franco, D, Freeman, J, Freestone, J, Fried, J, Friedland, A, Fuess, S, Furic, I, Furmanski, A, Gago, A, Gallagher, H, Gallego-Ros, A, Gallice, N, Galymov, V, Gamberini, E, Gamble, T, Gandhi, R, Gandrajula, R, Gao, S, Garcia-Gamez, D, Garcia-Peris, M, Gardiner, S, Gastler, D, Ge, G, Gelli, B, Gendotti, A, Gent, S, Ghorbani-Moghaddam, Z, Gibin, D, Gil-Botella, I, Girerd, C, Giri, A, Gnani, D, Gogota, O, Gold, M, Gollapinni, S, Gollwitzer, K, Gomes, R, Bermeo, L, Fajardo, L, Gonnella, F, Gonzalez-Cuevas, J, Goodman, M, Goodwin, O, Goswami, S, Gotti, C, Goudzovski, E, Grace, C, Graham, M, Gramellini, E, Gran, R, Granados, E, Grant, A, Grant, C, Gratieri, D, Green, P, Green, S, Greenler, L, Greenwood, M, Greer, J, Griffith, C, Groh, M, Grudzinski, J, Grzelak, K, Gu, W, Guarino, V, Guenette, R, Guglielmi, A, Guo, B, Guthikonda, K, Gutierrez, R, Guzowski, P, Guzzo, M, Gwon, S, Habig, A, Hackenburg, A, Hadavand, H, Haenni, R, Hahn, A, Haigh, J, Haiston, J, Hamernik, T, Hamilton, P, Han, J, Harder, K, Harris, D, Hartnell, J, Hasegawa, T, Hatcher, R, Hazen, E, Heavey, A, Heeger, K, Hennessy, K, Henry, S, Morquecho, M, Herner, K, Hertel, L, Hesam, A, Hewes, J, Pichardo, A, Hill, T, Hillier, S, Himmel, A, Hoff, J, Hohl, C, Holin, A, Hoppe, E, Horton-Smith, G, Hostert, M, Hourlier, A, Howard, B, Howell, R, Huang, J, Hugon, J, Iles, G, Iliescu, A, Illingworth, R, Ioannisian, A, Itay, R, Izmaylov, A, James, E, Jargowsky, B, Jediny, F, Jesus-Valls, C, Ji, X, Jiang, L, Jimenez, S, Jipa, A, Joglekar, A, Johnson, C, Johnson, R, Jones, B, Jones, S, Jung, C, Junk, T, Jwa, Y, Kabirnezhad, M, Kaboth, A, Kadenko, I, Kamiya, F, Karagiorgi, G, Karcher, A, Karolak, M, Karyotakis, Y, Kasai, S, Kasetti, S, Kashur, L, Kazaryan, N, Kearns, E, Keener, P, Kelly, K, Kemp, E, Ketchum, W, Kettell, S, Khabibullin, M, Khotjantsev, A, Khvedelidze, A, Kim, D, King, B, Kirby, B, Kirby, M, Klein, J, Koehler, K, Koerner, L, Kohn, S, Koller, P, Kordosky, M, Kosc, T, Kose, U, Kostelecky, V, Kothekar, K, Krennrich, F, Kreslo, I, Kudenko, Y, Kudryavtsev, V, Kulagin, S, Kumar, J, Kumar, R, Kuruppu, C, Kus, V, Kutter, T, Lambert, A, Lande, K, Lane, C, Lang, K, Langford, T, Lasorak, P, Last, D, Lastoria, C, Laundrie, A, Lawrence, A, Lazanu, I, Lazur, R, Le, T, Learned, J, Lebrun, P, Miotto, G, Lehnert, R, De Oliveira, M, Leitner, M, Leyton, M, Li, L, Li, S, Li, T, Li, Y, Liao, H, Lin, C, Lin, S, Lister, A, Littlejohn, B, Liu, J, Lockwitz, S, Loew, T, Lokajicek, M, Lomidze, I, Long, K, Loo, K, Lorca, D, Lord, T, Losecco, J, Louis, W, Luk, K, Luo, X, Lurkin, N, Lux, T, Luzio, V, Macfarland, D, Machado, A, Machado, P, Macias, C, Macier, J, Maddalena, A, Madigan, P, Magill, S, Mahn, K, Maio, A, Maloney, J, Mandrioli, G, Maneira, J, Manenti, L, Manly, S, Mann, A, Manolopoulos, K, Plata, M, Marchionni, A, Marciano, W, Marfatia, D, Mariani, C, Maricic, J, Marinho, F, Marino, A, Marshak, M, Marshall, C, Marshall, J, Marteau, J, Martin-Albo, J, Martinez, N, Caicedo, D, Martynenko, S, Mason, K, Mastbaum, A, Masud, M, Matsuno, S, Matthews, J, Mauger, C, Mauri, N, Mavrokoridis, K, Mazza, R, Mazzacane, A, Mazzucato, E, Mccluskey, E, Mcconkey, N, Mcfarland, K, Mcgrew, C, Mcnab, A, Mefodiev, A, Mehta, P, Melas, P, Mellinato, M, Mena, O, Menary, S, Mendez, H, Menegolli, A, Meng, G, Messier, M, Metcalf, W, Mewes, M, Meyer, H, Miao, T, Michna, G, Miedema, T, Migenda, J, Milincic, R, Miller, W, Mills, J, Milne, C, Mineev, O, Miranda, O, Miryala, S, Mishra, C, Mishra, S, Mislivec, A, Mladenov, D, Mocioiu, I, Moffat, K, Moggi, N, Mohanta, R, Mohayai, T, Mokhov, N, Molina, J, Bueno, L, Montanari, A, Montanari, C, Montanari, D, Zetina, L, Moon, J, Mooney, M, Moor, A, Moreno, D, Morgan, B, Morris, C, Mossey, C, Motuk, E, Moura, C, Mousseau, J, Mu, W, Mualem, L, Mueller, J, Muether, M, Mufson, S, Muheim, F, Muir, A, Mulhearn, M, Muramatsu, H, Murphy, S, Musser, J, Nachtman, J, Nagu, S, Nalbandyan, M, Nandakumar, R, Naples, D, Narita, S, Navas-Nicolas, D, Nayak, N, Nebot-Guinot, M, Necib, L, Negishi, K, Nelson, J, Nesbit, J, Nessi, M, Newbold, D, Newcomer, M, Newhart, D, Nichol, R, Niner, E, Nishimura, K, Norman, A, Northrop, R, Novella, P, Nowak, J, Oberling, M, Campo, A, Olivier, A, Onel, Y, Onishchuk, Y, Ott, J, Pagani, L, Pakvasa, S, Palamara, O, Palestini, S, Paley, J, Pallavicini, M, Palomares, C, Pantic, E, Paolone, V, Papadimitriou, V, Papaleo, R, Papanestis, A, Paramesvaran, S, Parke, S, Parsa, Z, Parvu, M, Pascoli, S, Pasqualini, L, Pasternak, J, Pater, J, Patrick, C, Patrizii, L, Patterson, R, Patton, S, Patzak, T, Paudel, A, Paulos, B, Paulucci, L, Pavlovic, Z, Pawloski, G, Payne, D, Pec, V, Peeters, S, Penichot, Y, Pennacchio, E, Penzo, A, Peres, O, Perry, J, Pershey, D, Pessina, G, Petrillo, G, Petta, C, Petti, R, Piastra, F, Pickering, L, Pietropaolo, F, Pillow, J, Plunkett, R, Poling, R, Pons, X, Poonthottathil, N, Pordes, S, Potekhin, M, Potenza, R, Potukuchi, B, Pozimski, J, Pozzato, M, Prakash, S, Prakash, T, Prince, S, Prior, G, Pugnere, D, Qi, K, Qian, X, Raaf, J, Raboanary, R, Radeka, V, Rademacker, J, Radics, B, Rafique, A, Raguzin, E, Rai, M, Rajaoalisoa, M, Rakhno, I, Rakotondramanana, H, Rakotondravohitra, L, Ramachers, Y, Rameika, R, Ramson, B, Rappoldi, A, Raselli, G, Ratoff, P, Ravat, S, Razafinime, H, Real, J, Rebel, B, Redondo, D, Reggiani-Guzzo, M, Rehak, T, Reichenbacher, J, Reitzner, S, Renshaw, A, Rescia, S, Resnati, F, Reynolds, A, Riccobene, G, Rice, L, Rielage, K, Rigaut, Y, Rivera, D, Rochester, L, Roda, M, Rodrigues, P, Alonso, M, Rondon, J, Roeth, A, Rogers, H, Rosauro-Alcaraz, S, Rossella, M, Rout, J, Roy, S, Rubbia, A, Rubbia, C, Russell, B, Russell, J, Ruterbories, D, Saakyan, R, Sacerdoti, S, Safford, T, Sahu, N, Sala, P, Samios, N, Sanchez, M, Sanders, D, Sankey, D, Santana, S, Santos-Maldonado, M, Saoulidou, N, Sapienza, P, Sarasty, C, Sarcevic, I, Savage, G, Savinov, V, Scaramelli, A, Scarff, A, Scarpelli, A, Schaffer, T, Schellman, H, Schlabach, P, Schmitz, D, Scholberg, K, Schukraft, A, Segreto, E, Sensenig, J, Seong, I, Sergi, A, Sergiampietri, F, Sgalaberna, D, Shaevitz, M, Shafaq, S, Shamma, M, Sharma, H, Sharma, R, Shaw, T, Shepherd-Themistocleous, C, Shin, S, Shooltz, D, Shrock, R, Simard, L, Simos, N, Sinclair, J, Sinev, G, Singh, J, Singh, V, Sipos, R, Sippach, F, Sirri, G, Sitraka, A, Siyeon, K, Smargianaki, D, Smith, A, Smith, E, Smith, P, Smolik, J, Smy, M, Snopok, P, Nunes, M, Sobel, H, Soderberg, M, Salinas, C, Soldner-Rembold, S, Solomey, N, Solovov, V, Sondheim, W, Sorel, M, Soto-Oton, J, Sousa, A, Soustruznik, K, Spagliardi, F, Spanu, M, Spitz, J, Spooner, N, Spurgeon, K, Staley, R, Stancari, M, Stanco, L, Steiner, H, Stewart, J, Stillwell, B, Stock, J, Stocker, F, Stokes, T, Strait, M, Strauss, T, Striganov, S, Stuart, A, Summers, D, Surdo, A, Susic, V, Suter, L, Sutera, C, Svoboda, R, Szczerbinska, B, Szelc, A, Talaga, R, Tanaka, H, Oregui, B, Tapper, A, Tariq, S, Tatar, E, Tayloe, R, Teklu, A, Tenti, M, Terao, K, Ternes, C, Terranova, F, Testera, G, Thea, A, Thompson, J, Thorn, C, Timm, S, Tonazzo, A, Torti, M, Tortola, M, Tortorici, F, Totani, D, Toups, M, Touramanis, C, Trevor, J, Trzaska, W, Tsai, Y, Tsamalaidze, Z, Tsang, K, Tsverava, N, Tufanli, S, Tull, C, Tyley, E, Tzanov, M, Uchida, M, Urheim, J, Usher, T, Vagins, M, Vahle, P, Valdiviesso, G, Valencia, E, Vallari, Z, Valle, J, Vallecorsa, S, Berg, R, De Water, R, Forero, D, Varanini, F, Vargas, D, Varner, G, Vasel, J, Vasseur, G, Vaziri, K, Ventura, S, Verdugo, A, Vergani, S, Vermeulen, M, Verzocchi, M, De Souza, H, Vignoli, C, Vilela, C, Viren, B, Vrba, T, Wachala, T, Waldron, A, Wallbank, M, Wang, H, Wang, J, Wang, Y, Warburton, K, Warner, D, Wascko, M, Waters, D, Watson, A, Weatherly, P, Weber, A, Weber, M, Wei, H, Weinstein, A, Wenman, D, Wetstein, M, While, M, White, A, Whitehead, L, Whittington, D, Wilking, M, Wilkinson, C, Williams, Z, Wilson, F, Wilson, R, Wolcott, J, Wongjirad, T, Wood, K, Wood, L, Worcester, E, Worcester, M, Wret, C, Wu, W, Xiao, Y, Yang, G, Yang, T, Yershov, N, Yonehara, K, Young, T, Yu, B, Yu, J, Zalesak, J, Zambelli, L, Zamorano, B, Zani, A, Zazueta, L, Zeller, G, Zennamo, J, Zeug, K, Zhang, C, Zhao, M, Zhivun, E, Zhu, G, Zimmerman, E, Zito, M, Zucchelli, S, Zuklin, J, Zutshi, V, Zwaska, R, Abi, B., Acciarri, R., Acero, M. A., Adamov, G., Adams, D., Adinolfi, M., Ahmad, Z., Ahmed, J., Alion, T., Monsalve, S. Alonso, Alt, C., Anderson, J., Andreopoulos, C., Andrews, M., Andrianala, F., Andringa, S., Ankowski, A., Antonova, M., Antusch, S., Aranda-Fernandez, A., Ariga, A., Arnold, L. O., Arroyave, M. A., Asaadi, J., Aurisano, A., Aushev, V., Autiero, D., Azfar, F., Back, H., Back, J. J., Backhouse, C., Baesso, P., Bagby, L., Bajou, R., Balasubramanian, S., Baldi, P., Bambah, B., Barao, F., Barenboim, G., Barker, G., Barkhouse, W., Barnes, C., Barr, G., Monarca, J. Barranco, Barros, N., Barrow, J. L., Bashyal, A., Basque, V., Bay, F., Alba, J. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Belver, D., Benekos, N., Neves, F. Bento, Berger, J., Berkman, S., Bernardini, P., Berner, R. M., Berns, H., Bertolucci, S., Betancourt, M., Bezawada, Y., Bhattacharjee, M., Bhuyan, B., Biagi, S., Bian, J., Biassoni, M., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Siffert, B. Blanco, Blaszczyk, F., Blazey, G., Blucher, E., Boissevain, J., Bolognesi, S., Bolton, T., Bonesini, M., Bongrand, M., Bonini, F., Booth, A., Booth, C., Bordoni, S., Borkum, A., Boschi, T., Bostan, N., Bour, P., Boyd, S., Boyden, D., Bracinik, J., Braga, D., Brailsford, D., Brandt, A., Bremer, J., Brew, C., Brianne, E., Brice, S. J., Brizzolari, C., Bromberg, C., Brooijmans, G., Brooke, J., Bross, A., Brunetti, G., Buchanan, N., Budd, H., Caiulo, D., Calafiura, P., Calcutt, J., Calin, M., Calvez, S., Calvo, E., Camilleri, L., Caminata, A., Campanelli, M., Caratelli, D., Carini, G., Carlus, B., Carniti, P., Terrazas, I. Caro, Carranza, H., Castillo, A., Castromonte, C., Cattadori, C., Cavalier, F., Cavanna, F., Centro, S., Cerati, G., Cervelli, A., Villanueva, A. Cervera, Chalifour, M., Chang, C., Chardonnet, E., Chatterjee, A., Chattopadhyay, S., Chaves, J., Chen, H., Chen, M., Chen, Y., Cherdack, D., Chi, C., Childress, S., Chiriacescu, A., Cho, K., Choubey, S., Christensen, A., Christian, D., Christodoulou, G., Church, E., Clarke, P., Coan, T. E., Cocco, A. G., Coelho, J., Conley, E., Conrad, J., Convery, M., Corwin, L., Cotte, P., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Cristaldo, E., Cross, R., Cuesta, C., Cui, Y., Cussans, D., Dabrowski, M., Motta, H. Da, Peres, L. Da Silva, David, Q., Davies, G. S., Davini, S., Dawson, J., De, K., Almeida, R. M. De, Debbins, P., Bonis, I. De, Decowski, M., Gouvea, A. De, Holanda, P. C. De, Astiz, I. L. De Icaza, Deisting, A., Jong, P. De, Delbart, A., Delepine, D., Delgado, M., Dell'Acqua, A., Lurgio, P. De, Neto, J. R. De Mello, Demuth, D. M., Dennis, S., Densham, C., Deptuch, G., Roeck, A. De, Romeri, V. De, Vries, J. De, Dharmapalan, R., Dias, M., Diaz, F., Diaz, J., Domizio, S. Di, Giulio, L. Di, Ding, P., Noto, L. Di, Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Dokania, N., Dolinski, M., Domine, L., Douglas, D., Drielsma, F., Duchesneau, D., Duffy, K., Dunne, P., Durkin, T., Duyang, H., Dvornikov, O., Dwyer, D., Dyshkant, A., Eads, M., Edmunds, D., Eisch, J., Emery, S., Ereditato, A., Escobar, C., Sanchez, L. Escudero, Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Falcone, A., Farnese, C., Farzan, Y., Felix, J., Fernandez-Martinez, E., Menendez, P. Fernandez, Ferraro, F., Fields, L., Filkins, A., Filthaut, F., Fitzpatrick, R. S., Flanagan, W., Fleming, B., Flight, R., Fowler, J., Fox, W., Franc, J., Francis, K., Franco, D., Freeman, J., Freestone, J., Fried, J., Friedland, A., Fuess, S., Furic, I., Furmanski, A. P., Gago, A., Gallagher, H., Gallego-Ros, A., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Gandhi, R., Gandrajula, R., Gao, S., Garcia-Gamez, D., García-Peris, M. Á., Gardiner, S., Gastler, D., Ge, G., Gelli, B., Gendotti, A., Gent, S., Ghorbani-Moghaddam, Z., Gibin, D., Gil-Botella, I., Girerd, C., Giri, A., Gnani, D., Gogota, O., Gold, M., Gollapinni, S., Gollwitzer, K., Gomes, R. A., Bermeo, L. Gomez, Fajardo, L. S. Gomez, Gonnella, F., Gonzalez-Cuevas, J., Goodman, M. C., Goodwin, O., Goswami, S., Gotti, C., Goudzovski, E., Grace, C., Graham, M., Gramellini, E., Gran, R., Granados, E., Grant, A., Grant, C., Gratieri, D., Green, P., Green, S., Greenler, L., Greenwood, M., Greer, J., Griffith, C., Groh, M., Grudzinski, J., Grzelak, K., Gu, W., Guarino, V., Guenette, R., Guglielmi, A., Guo, B., Guthikonda, K., Gutierrez, R., Guzowski, P., Guzzo, M. M., Gwon, S., Habig, A., Hackenburg, A., Hadavand, H., Haenni, R., Hahn, A., Haigh, J., Haiston, J., Hamernik, T., Hamilton, P., Han, J., Harder, K., Harris, D. A., Hartnell, J., Hasegawa, T., Hatcher, R., Hazen, E., Heavey, A., Heeger, K. M., Hennessy, K., Henry, S., Morquecho, M. Hernandez, Herner, K., Hertel, L., Hesam, A. S., Hewes, J., Pichardo, A. Higuera, Hill, T., Hillier, S. J., Himmel, A., Hoff, J., Hohl, C., Holin, A., Hoppe, E., Horton-Smith, G. A., Hostert, M., Hourlier, A., Howard, B., Howell, R., Huang, J., Hugon, J., Iles, G., Iliescu, A. M., Illingworth, R., Ioannisian, A., Itay, R., Izmaylov, A., James, E., Jargowsky, B., Jediny, F., Jesús-Valls, C., Ji, X., Jiang, L., Jiménez, S., Jipa, A., Joglekar, A., Johnson, C., Johnson, R., Jones, B., Jones, S., Jung, C., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A., Kadenko, I., Kamiya, F., Karagiorgi, G., Karcher, A., Karolak, M., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Kazaryan, N., Kearns, E., Keener, P., Kelly, K. J., Kemp, E., Ketchum, W., Kettell, S., Khabibullin, M., Khotjantsev, A., Khvedelidze, A., Kim, D., King, B., Kirby, B., Kirby, M., Klein, J., Koehler, K., Koerner, L. W., Kohn, S., Koller, P. P., Kordosky, M., Kosc, T., Kose, U., Kostelecky, V., Kothekar, K., Krennrich, F., Kreslo, I., Kudenko, Y., Kudryavtsev, V., Kulagin, S., Kumar, J., Kumar, R., Kuruppu, C., Kus, V., Kutter, T., Lambert, A., Lande, K., Lane, C. E., Lang, K., Langford, T., Lasorak, P., Last, D., Lastoria, C., Laundrie, A., Lawrence, A., Lazanu, I., Lazur, R., Le, T., Learned, J., Lebrun, P., Miotto, G. Lehmann, Lehnert, R., de Oliveira, M. Leigui, Leitner, M., Leyton, M., Li, L., Li, S., Li, T., Li, Y., Liao, H., Lin, C., Lin, S., Lister, A., Littlejohn, B. R., Liu, J., Lockwitz, S., Loew, T., Lokajicek, M., Lomidze, I., Long, K., Loo, K., Lorca, D., Lord, T., Losecco, J., Louis, W. C., Luk, K., Luo, X., Lurkin, N., Lux, T., Luzio, V. P., Macfarland, D., Machado, A., Machado, P., Macias, C., Macier, J., Maddalena, A., Madigan, P., Magill, S., Mahn, K., Maio, A., Maloney, J. A., Mandrioli, G., Maneira, J. C., Manenti, L., Manly, S., Mann, A., Manolopoulos, K., Plata, M. Manrique, Marchionni, A., Marciano, W., Marfatia, D., Mariani, C., Maricic, J., Marinho, F., Marino, A. D., Marshak, M., Marshall, C., Marshall, J., Marteau, J., Martin-Albo, J., Martinez, N., Caicedo, D. A. Martinez, Martynenko, S., Mason, K., Mastbaum, A., Masud, M., Matsuno, S., Matthews, J., Mauger, C., Mauri, N., Mavrokoridis, K., Mazza, R., Mazzacane, A., Mazzucato, E., Mccluskey, E., Mcconkey, N., Mcfarland, K. S., Mcgrew, C., Mcnab, A., Mefodiev, A., Mehta, P., Melas, P., Mellinato, M., Mena, O., Menary, S., Mendez, H., Menegolli, A., Meng, G., Messier, M., Metcalf, W., Mewes, M., Meyer, H., Miao, T., Michna, G., Miedema, T., Migenda, J., Milincic, R., Miller, W., Mills, J., Milne, C., Mineev, O., Miranda, O. G., Miryala, S., Mishra, C., Mishra, S., Mislivec, A., Mladenov, D., Mocioiu, I., Moffat, K., Moggi, N., Mohanta, R., Mohayai, T. A., Mokhov, N., Molina, J. A., Bueno, L. Molina, Montanari, A., Montanari, C., Montanari, D., Zetina, L. M. Montano, Moon, J., Mooney, M., Moor, A., Moreno, D., Morgan, B., Morris, C., Mossey, C., Motuk, E., Moura, C. A., Mousseau, J., Mu, W., Mualem, L., Mueller, J., Muether, M., Mufson, S., Muheim, F., Muir, A., Mulhearn, M., Muramatsu, H., Murphy, S., Musser, J., Nachtman, J., Nagu, S., Nalbandyan, M., Nandakumar, R., Naples, D., Narita, S., Navas-Nicolás, D., Nayak, N., Nebot-Guinot, M., Necib, L., Negishi, K., Nelson, J. K., Nesbit, J., Nessi, M., Newbold, D., Newcomer, M., Newhart, D., Nichol, R., Niner, E., Nishimura, K., Norman, A., Northrop, R., Novella, P., Nowak, J. A., Oberling, M., Campo, A. Olivares Del, Olivier, A., Onel, Y., Onishchuk, Y., Ott, J., Pagani, L., Pakvasa, S., Palamara, O., Palestini, S., Paley, J. M., Pallavicini, M., Palomares, C., Pantic, E., Paolone, V., Papadimitriou, V., Papaleo, R., Papanestis, A., Paramesvaran, S., Parke, S., Parsa, Z., Parvu, M., Pascoli, S., Pasqualini, L., Pasternak, J., Pater, J., Patrick, C., Patrizii, L., Patterson, R. B., Patton, S., Patzak, T., Paudel, A., Paulos, B., Paulucci, L., Pavlovic, Z., Pawloski, G., Payne, D., Pec, V., Peeters, S. J., Penichot, Y., Pennacchio, E., Penzo, A., Peres, O. L., Perry, J., Pershey, D., Pessina, G., Petrillo, G., Petta, C., Petti, R., Piastra, F., Pickering, L., Pietropaolo, F., Pillow, J., Plunkett, R., Poling, R., Pons, X., Poonthottathil, N., Pordes, S., Potekhin, M., Potenza, R., Potukuchi, B. V., Pozimski, J., Pozzato, M., Prakash, S., Prakash, T., Prince, S., Prior, G., Pugnere, D., Qi, K., Qian, X., Raaf, J., Raboanary, R., Radeka, V., Rademacker, J., Radics, B., Rafique, A., Raguzin, E., Rai, M., Rajaoalisoa, M., Rakhno, I., Rakotondramanana, H., Rakotondravohitra, L., Ramachers, Y., Rameika, R., Delgado, M. Ramirez, Ramson, B., Rappoldi, A., Raselli, G., Ratoff, P., Ravat, S., Razafinime, H., Real, J., Rebel, B., Redondo, D., Reggiani-Guzzo, M., Rehak, T., Reichenbacher, J., Reitzner, S. D., Renshaw, A., Rescia, S., Resnati, F., Reynolds, A., Riccobene, G., Rice, L. C., Rielage, K., Rigaut, Y., Rivera, D., Rochester, L., Roda, M., Rodrigues, P., Alonso, M. Rodriguez, Rondon, J. Rodriguez, Roeth, A., Rogers, H., Rosauro-Alcaraz, S., Rossella, M., Rout, J., Roy, S., Rubbia, A., Rubbia, C., Russell, B., Russell, J., Ruterbories, D., Saakyan, R., Sacerdoti, S., Safford, T., Sahu, N., Sala, P., Samios, N., Sanchez, M., Sanders, D. A., Sankey, D., Santana, S., Santos-Maldonado, M., Saoulidou, N., Sapienza, P., Sarasty, C., Sarcevic, I., Savage, G., Savinov, V., Scaramelli, A., Scarff, A., Scarpelli, A., Schaffer, T., Schellman, H., Schlabach, P., Schmitz, D., Scholberg, K., Schukraft, A., Segreto, E., Sensenig, J., Seong, I., Sergi, A., Sergiampietri, F., Sgalaberna, D., Shaevitz, M., Shafaq, S., Shamma, M., Sharma, H. R., Sharma, R., Shaw, T., Shepherd-Themistocleous, C., Shin, S., Shooltz, D., Shrock, R., Simard, L., Simos, N., Sinclair, J., Sinev, G., Singh, J., Singh, V., Sipos, R., Sippach, F., Sirri, G., Sitraka, A., Siyeon, K., Smargianaki, D., Smith, A., Smith, E., Smith, P., Smolik, J., Smy, M., Snopok, P., Nunes, M. Soare, Sobel, H., Soderberg, M., Salinas, C. J. Solano, Söldner-Rembold, S., Solomey, N., Solovov, V., Sondheim, W. E., Sorel, M., Soto-Oton, J., Sousa, A., Soustruznik, K., Spagliardi, F., Spanu, M., Spitz, J., Spooner, N. J., Spurgeon, K., Staley, R., Stancari, M., Stanco, L., Steiner, H., Stewart, J., Stillwell, B., Stock, J., Stocker, F., Stokes, T., Strait, M., Strauss, T., Striganov, S., Stuart, A., Summers, D., Surdo, A., Susic, V., Suter, L., Sutera, C., Svoboda, R., Szczerbinska, B., Szelc, A., Talaga, R., Tanaka, H., Oregui, B. Tapia, Tapper, A., Tariq, S., Tatar, E., Tayloe, R., Teklu, A., Tenti, M., Terao, K., Ternes, C. A., Terranova, F., Testera, G., Thea, A., Thompson, J. L., Thorn, C., Timm, S., Tonazzo, A., Torti, M., Tortola, M., Tortorici, F., Totani, D., Toups, M., Touramanis, C., Trevor, J., Trzaska, W. H., Tsai, Y. T., Tsamalaidze, Z., Tsang, K., Tsverava, N., Tufanli, S., Tull, C., Tyley, E., Tzanov, M., Uchida, M. A., Urheim, J., Usher, T., Vagins, M., Vahle, P., Valdiviesso, G., Valencia, E., Vallari, Z., Valle, J. W., Vallecorsa, S., Berg, R. Van, de Water, R. G. Van, Forero, D. Vanega, Varanini, F., Vargas, D., Varner, G., Vasel, J., Vasseur, G., Vaziri, K., Ventura, S., Verdugo, A., Vergani, S., Vermeulen, M. A., Verzocchi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Viren, B., Vrba, T., Wachala, T., Waldron, A. V., Wallbank, M., Wang, H., Wang, J., Wang, Y., Warburton, K., Warner, D., Wascko, M., Waters, D., Watson, A., Weatherly, P., Weber, A., Weber, M., Wei, H., Weinstein, A., Wenman, D., Wetstein, M., While, M. R., White, A., Whitehead, L. H., Whittington, D., Wilking, M. J., Wilkinson, C., Williams, Z., Wilson, F., Wilson, R. J., Wolcott, J., Wongjirad, T., Wood, K., Wood, L., Worcester, E., Worcester, M., Wret, C., Wu, W., Xiao, Y., Yang, G., Yang, T., Yershov, N., Yonehara, K., Young, T., Yu, B., Yu, J., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zazueta, L., Zeller, G., Zennamo, J., Zeug, K., Zhang, C., Zhao, M., Zhivun, E., Zhu, G., Zimmerman, E. D., Zito, M., Zucchelli, S., Zuklin, J., Zutshi, V., Zwaska, R., Abi B., Acciarri R., Acero M.A., Adamov G., Adams D., Adinolfi M., Ahmad Z., Ahmed J., Alion T., Monsalve S.A., Alt C., Anderson J., Andreopoulos C., Andrews M., Andrianala F., Andringa S., Ankowski A., Antonova M., Antusch S., Aranda-Fernandez A., Ariga A., Arnold L.O., Arroyave M.A., Asaadi J., Aurisano A., Aushev V., Autiero D., Azfar F., Back H., Back J.J., Backhouse C., Baesso P., Bagby L., Bajou R., Balasubramanian S., Baldi P., Bambah B., Barao F., Barenboim G., Barker G., Barkhouse W., Barnes C., Barr G., Monarca J.B., Barros N., Barrow J.L., Bashyal A., Basque V., Bay F., Alba J.B., Beacom J.F., Bechetoille E., Behera B., Bellantoni L., Bellettini G., Bellini V., Beltramello O., Belver D., Benekos N., Neves F.B., Berger J., Berkman S., Bernardini P., Berner R.M., Berns H., Bertolucci S., Betancourt M., Bezawada Y., Bhattacharjee M., Bhuyan B., Biagi S., Bian J., Biassoni M., Biery K., Bilki B., Bishai M., Bitadze A., Blake A., Siffert B.B., Blaszczyk F., Blazey G., Blucher E., Boissevain J., Bolognesi S., Bolton T., Bonesini M., Bongrand M., Bonini F., Booth A., Booth C., Bordoni S., Borkum A., Boschi T., Bostan N., Bour P., Boyd S., Boyden D., Bracinik J., Braga D., Brailsford D., Brandt A., Bremer J., Brew C., Brianne E., Brice S.J., Brizzolari C., Bromberg C., Brooijmans G., Brooke J., Bross A., Brunetti G., Buchanan N., Budd H., Caiulo D., Calafiura P., Calcutt J., Calin M., Calvez S., Calvo E., Camilleri L., Caminata A., Campanelli M., Caratelli D., Carini G., Carlus B., Carniti P., Terrazas I.C., Carranza H., Castillo A., Castromonte C., Cattadori C., Cavalier F., Cavanna F., Centro S., Cerati G., Cervelli A., Villanueva A.C., Chalifour M., Chang C., Chardonnet E., Chatterjee A., Chattopadhyay S., Chaves J., Chen H., Chen M., Chen Y., Cherdack D., Chi C., Childress S., Chiriacescu A., Cho K., Choubey S., Christensen A., Christian D., Christodoulou G., Church E., Clarke P., Coan T.E., Cocco A.G., Coelho J., Conley E., Conrad J., Convery M., Corwin L., Cotte P., Cremaldi L., Cremonesi L., Crespo-Anadon J.I., Cristaldo E., Cross R., Cuesta C., Cui Y., Cussans D., Dabrowski M., Motta H.D., Peres L.D.S., David Q., Davies G.S., Davini S., Dawson J., De K., Almeida R.M.D., Debbins P., Bonis I.D., Decowski M., Gouvea A.D., Holanda P.C.D., Astiz I.L.D.I., Deisting A., Jong P.D., Delbart A., Delepine D., Delgado M., Dell'acqua A., Lurgio P.D., Neto J.R.D.M., Demuth D.M., Dennis S., Densham C., Deptuch G., Roeck A.D., Romeri V.D., Vries J.D., Dharmapalan R., Dias M., Diaz F., Diaz J., Domizio S.D., Giulio L.D., Ding P., Noto L.D., Distefano C., Diurba R., Diwan M., Djurcic Z., Dokania N., Dolinski M., Domine L., Douglas D., Drielsma F., Duchesneau D., Duffy K., Dunne P., Durkin T., Duyang H., Dvornikov O., Dwyer D., Dyshkant A., Eads M., Edmunds D., Eisch J., Emery S., Ereditato A., Escobar C., Sanchez L.E., Evans J.J., Ewart E., Ezeribe A.C., Fahey K., Falcone A., Farnese C., Farzan Y., Felix J., Fernandez-Martinez E., Menendez P.F., Ferraro F., Fields L., Filkins A., Filthaut F., Fitzpatrick R.S., Flanagan W., Fleming B., Flight R., Fowler J., Fox W., Franc J., Francis K., Franco D., Freeman J., Freestone J., Fried J., Friedland A., Fuess S., Furic I., Furmanski A.P., Gago A., Gallagher H., Gallego-Ros A., Gallice N., Galymov V., Gamberini E., Gamble T., Gandhi R., Gandrajula R., Gao S., Garcia-Gamez D., Garcia-Peris M.A., Gardiner S., Gastler D., Ge G., Gelli B., Gendotti A., Gent S., Ghorbani-Moghaddam Z., Gibin D., Gil-Botella I., Girerd C., Giri A., Gnani D., Gogota O., Gold M., Gollapinni S., Gollwitzer K., Gomes R.A., Bermeo L.G., Fajardo L.S.G., Gonnella F., Gonzalez-Cuevas J., Goodman M.C., Goodwin O., Goswami S., Gotti C., Goudzovski E., Grace C., Graham M., Gramellini E., Gran R., Granados E., Grant A., Grant C., Gratieri D., Green P., Green S., Greenler L., Greenwood M., Greer J., Griffith C., Groh M., Grudzinski J., Grzelak K., Gu W., Guarino V., Guenette R., Guglielmi A., Guo B., Guthikonda K., Gutierrez R., Guzowski P., Guzzo M.M., Gwon S., Habig A., Hackenburg A., Hadavand H., Haenni R., Hahn A., Haigh J., Haiston J., Hamernik T., Hamilton P., Han J., Harder K., Harris D.A., Hartnell J., Hasegawa T., Hatcher R., Hazen E., Heavey A., Heeger K.M., Hennessy K., Henry S., Morquecho M.H., Herner K., Hertel L., Hesam A.S., Hewes J., Pichardo A.H., Hill T., Hillier S.J., Himmel A., Hoff J., Hohl C., Holin A., Hoppe E., Horton-Smith G.A., Hostert M., Hourlier A., Howard B., Howell R., Huang J., Hugon J., Iles G., Iliescu A.M., Illingworth R., Ioannisian A., Itay R., Izmaylov A., James E., Jargowsky B., Jediny F., Jesus-Valls C., Ji X., Jiang L., Jimenez S., Jipa A., Joglekar A., Johnson C., Johnson R., Jones B., Jones S., Jung C., Junk T., Jwa Y., Kabirnezhad M., Kaboth A., Kadenko I., Kamiya F., Karagiorgi G., Karcher A., Karolak M., Karyotakis Y., Kasai S., Kasetti S.P., Kashur L., Kazaryan N., Kearns E., Keener P., Kelly K.J., Kemp E., Ketchum W., Kettell S., Khabibullin M., Khotjantsev A., Khvedelidze A., Kim D., King B., Kirby B., Kirby M., Klein J., Koehler K., Koerner L.W., Kohn S., Koller P.P., Kordosky M., Kosc T., Kose U., Kostelecky V., Kothekar K., Krennrich F., Kreslo I., Kudenko Y., Kudryavtsev V., Kulagin S., Kumar J., Kumar R., Kuruppu C., Kus V., Kutter T., Lambert A., Lande K., Lane C.E., Lang K., Langford T., Lasorak P., Last D., Lastoria C., Laundrie A., Lawrence A., Lazanu I., Lazur R., Le T., Learned J., Lebrun P., Miotto G.L., Lehnert R., De Oliveira M.L., Leitner M., Leyton M., Li L., Li S., Li T., Li Y., Liao H., Lin C., Lin S., Lister A., Littlejohn B.R., Liu J., Lockwitz S., Loew T., Lokajicek M., Lomidze I., Long K., Loo K., Lorca D., Lord T., Losecco J., Louis W.C., Luk K., Luo X., Lurkin N., Lux T., Luzio V.P., MacFarland D., MacHado A., MacHado P., MacIas C., MacIer J., Maddalena A., Madigan P., Magill S., Mahn K., Maio A., Maloney J.A., Mandrioli G., Maneira J.C., Manenti L., Manly S., Mann A., Manolopoulos K., Plata M.M., Marchionni A., Marciano W., Marfatia D., Mariani C., Maricic J., Marinho F., Marino A.D., Marshak M., Marshall C., Marshall J., Marteau J., Martin-Albo J., Martinez N., Caicedo D.A.M., Martynenko S., Mason K., Mastbaum A., Masud M., Matsuno S., Matthews J., Mauger C., Mauri N., Mavrokoridis K., Mazza R., Mazzacane A., Mazzucato E., McCluskey E., McConkey N., McFarland K.S., McGrew C., McNab A., Mefodiev A., Mehta P., Melas P., Mellinato M., Mena O., Menary S., Mendez H., Menegolli A., Meng G., Messier M., Metcalf W., Mewes M., Meyer H., Miao T., Michna G., Miedema T., Migenda J., Milincic R., Miller W., Mills J., Milne C., Mineev O., Miranda O.G., Miryala S., Mishra C., Mishra S., Mislivec A., Mladenov D., Mocioiu I., Moffat K., Moggi N., Mohanta R., Mohayai T.A., Mokhov N., Molina J.A., Bueno L.M., Montanari A., Montanari C., Montanari D., Zetina L.M.M., Moon J., Mooney M., Moor A., Moreno D., Morgan B., Morris C., Mossey C., Motuk E., Moura C.A., Mousseau J., Mu W., Mualem L., Mueller J., Muether M., Mufson S., Muheim F., Muir A., Mulhearn M., Muramatsu H., Murphy S., Musser J., Nachtman J., Nagu S., Nalbandyan M., Nandakumar R., Naples D., Narita S., Navas-Nicolas D., Nayak N., Nebot-Guinot M., Necib L., Negishi K., Nelson J.K., Nesbit J., Nessi M., Newbold D., Newcomer M., Newhart D., Nichol R., Niner E., Nishimura K., Norman A., Northrop R., Novella P., Nowak J.A., Oberling M., Campo A.O.D., Olivier A., Onel Y., Onishchuk Y., Ott J., Pagani L., Pakvasa S., Palamara O., Palestini S., Paley J.M., Pallavicini M., Palomares C., Pantic E., Paolone V., Papadimitriou V., Papaleo R., Papanestis A., Paramesvaran S., Parke S., Parsa Z., Parvu M., Pascoli S., Pasqualini L., Pasternak J., Pater J., Patrick C., Patrizii L., Patterson R.B., Patton S., Patzak T., Paudel A., Paulos B., Paulucci L., Pavlovic Z., Pawloski G., Payne D., Pec V., Peeters S.J., Penichot Y., Pennacchio E., Penzo A., Peres O.L., Perry J., Pershey D., Pessina G., Petrillo G., Petta C., Petti R., Piastra F., Pickering L., Pietropaolo F., Pillow J., Plunkett R., Poling R., Pons X., Poonthottathil N., Pordes S., Potekhin M., Potenza R., Potukuchi B.V., Pozimski J., Pozzato M., Prakash S., Prakash T., Prince S., Prior G., Pugnere D., Qi K., Qian X., Raaf J., Raboanary R., Radeka V., Rademacker J., Radics B., Rafique A., Raguzin E., Rai M., Rajaoalisoa M., Rakhno I., Rakotondramanana H., Rakotondravohitra L., Ramachers Y., Rameika R., Delgado M.R., Ramson B., Rappoldi A., Raselli G., Ratoff P., Ravat S., Razafinime H., Real J., Rebel B., Redondo D., Reggiani-Guzzo M., Rehak T., Reichenbacher J., Reitzner S.D., Renshaw A., Rescia S., Resnati F., Reynolds A., Riccobene G., Rice L.C., Rielage K., Rigaut Y., Rivera D., Rochester L., Roda M., Rodrigues P., Alonso M.R., Rondon J.R., Roeth A., Rogers H., Rosauro-Alcaraz S., Rossella M., Rout J., Roy S., Rubbia A., Rubbia C., Russell B., Russell J., Ruterbories D., Saakyan R., Sacerdoti S., Safford T., Sahu N., Sala P., Samios N., Sanchez M., Sanders D.A., Sankey D., Santana S., Santos-Maldonado M., Saoulidou N., Sapienza P., Sarasty C., Sarcevic I., Savage G., Savinov V., Scaramelli A., Scarff A., Scarpelli A., Schaffer T., Schellman H., Schlabach P., Schmitz D., Scholberg K., Schukraft A., Segreto E., Sensenig J., Seong I., Sergi A., Sergiampietri F., Sgalaberna D., Shaevitz M., Shafaq S., Shamma M., Sharma H.R., Sharma R., Shaw T., Shepherd-Themistocleous C., Shin S., Shooltz D., Shrock R., Simard L., Simos N., Sinclair J., Sinev G., Singh J., Singh V., Sipos R., Sippach F., Sirri G., Sitraka A., Siyeon K., Smargianaki D., Smith A., Smith E., Smith P., Smolik J., Smy M., Snopok P., Nunes M.S., Sobel H., Soderberg M., Salinas C.J.S., Soldner-Rembold S., Solomey N., Solovov V., Sondheim W.E., Sorel M., Soto-Oton J., Sousa A., Soustruznik K., Spagliardi F., Spanu M., Spitz J., Spooner N.J., Spurgeon K., Staley R., Stancari M., Stanco L., Steiner H., Stewart J., Stillwell B., Stock J., Stocker F., Stokes T., Strait M., Strauss T., Striganov S., Stuart A., Summers D., Surdo A., Susic V., Suter L., Sutera C., Svoboda R., Szczerbinska B., Szelc A., Talaga R., Tanaka H., Oregui B.T., Tapper A., Tariq S., Tatar E., Tayloe R., Teklu A., Tenti M., Terao K., Ternes C.A., Terranova F., Testera G., Thea A., Thompson J.L., Thorn C., Timm S., Tonazzo A., Torti M., Tortola M., Tortorici F., Totani D., Toups M., Touramanis C., Trevor J., Trzaska W.H., Tsai Y.T., Tsamalaidze Z., Tsang K., Tsverava N., Tufanli S., Tull C., Tyley E., Tzanov M., Uchida M.A., Urheim J., Usher T., Vagins M., Vahle P., Valdiviesso G., Valencia E., Vallari Z., Valle J.W., Vallecorsa S., Berg R.V., De Water R.G.V., Forero D.V., Varanini F., Vargas D., Varner G., Vasel J., Vasseur G., Vaziri K., Ventura S., Verdugo A., Vergani S., Vermeulen M.A., Verzocchi M., De Souza H.V., Vignoli C., Vilela C., Viren B., Vrba T., Wachala T., Waldron A.V., Wallbank M., Wang H., Wang J., Wang Y., Warburton K., Warner D., Wascko M., Waters D., Watson A., Weatherly P., Weber A., Weber M., Wei H., Weinstein A., Wenman D., Wetstein M., While M.R., White A., Whitehead L.H., Whittington D., Wilking M.J., Wilkinson C., Williams Z., Wilson F., Wilson R.J., Wolcott J., Wongjirad T., Wood K., Wood L., Worcester E., Worcester M., Wret C., Wu W., Xiao Y., Yang G., Yang T., Yershov N., Yonehara K., Young T., Yu B., Yu J., Zalesak J., Zambelli L., Zamorano B., Zani A., Zazueta L., Zeller G., Zennamo J., Zeug K., Zhang C., Zhao M., Zhivun E., Zhu G., Zimmerman E.D., Zito M., Zucchelli S., Zuklin J., Zutshi V., and Zwaska R.
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Technology ,530 Physics ,media_common.quotation_subject ,Neutrino oscillations, liquid Argon TPC, DUNE technical design report, single phase LArTPC ,Electrons ,FREE-ELECTRONS ,01 natural sciences ,7. Clean energy ,09 Engineering ,030218 nuclear medicine & medical imaging ,Standard Model ,03 medical and health sciences ,neutrino ,0302 clinical medicine ,LIQUID ARGON ,0103 physical sciences ,Grand Unified Theory ,High Energy Physics ,Aerospace engineering ,Instrumentation ,Instruments & Instrumentation ,Mathematical Physics ,media_common ,Physics ,Science & Technology ,02 Physical Sciences ,010308 nuclear & particles physics ,business.industry ,Detector ,Lıquıd Argonfree ,Nuclear & Particles Physics ,Symmetry (physics) ,Universe ,Long baseline neutrino experiment, CP violation ,Antimatter ,Neutrino ,business ,Event (particle physics) - Abstract
This document was prepared by the DUNE collaboration using the resources of the Fermi National Accelerator Laboratory (Fermilab), a U.S. Department of Energy, Office of Science, HEP User Facility. Fermilab is managed by Fermi Research Alliance, LLC (FRA), acting under Contract No. DE-AC02-07CH11359. The DUNE collaboration also acknowledges the international, national, and regional funding agencies supporting the institutions who have contributed to completing this Technical Design Report., The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay—these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. DUNE is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. Central to achieving DUNE's physics program is a far detector that combines the many tens-of-kiloton fiducial mass necessary for rare event searches with sub-centimeter spatial resolution in its ability to image those events, allowing identification of the physics signatures among the numerous backgrounds. In the single-phase liquid argon time-projection chamber (LArTPC) technology, ionization charges drift horizontally in the liquid argon under the influence of an electric field towards a vertical anode, where they are read out with fine granularity. A photon detection system supplements the TPC, directly enhancing physics capabilities for all three DUNE physics drivers and opening up prospects for further physics explorations. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. Volume IV presents an overview of the basic operating principles of a single-phase LArTPC, followed by a description of the DUNE implementation. Each of the subsystems is described in detail, connecting the high-level design requirements and decisions to the overriding physics goals of DUNE., Fermi Research Alliance, LLC (FRA) DE-AC02-07CH11359
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20. Using Integrated Ecosystem Assessments to Build Resilient Ecosystems, Communities, and Economies
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Steven J. Bograd, Sean M. Lucey, Jameal F. Samhouri, Ellen Spooner, Mark E. Monaco, Jamison M. Gove, Chris J. Harvey, Kathy Broughton, Patricia M. Clay, Rebecca J. Allee, Stephen R. Gittings, Kelly S. Andrews, Supin Wongbusarakum, Judith Rosellon-Druker, Anthony R. Marshak, Stephen Kasperski, Mandy Karnauskas, Christopher R. Kelble, Lauren A. Rogers, Jamal H. Moss, and Patrick D. Lynch
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0106 biological sciences ,010504 meteorology & atmospheric sciences ,business.industry ,010604 marine biology & hydrobiology ,Environmental resource management ,ComputingMilieux_LEGALASPECTSOFCOMPUTING ,01 natural sciences ,Ecosystem-based management ,Environmental Chemistry ,Ecosystem ,Natural resource management ,business ,0105 earth and related environmental sciences ,General Environmental Science - Abstract
Science-based natural resource management is necessary for agencies to effectively meet their goals and mandates. However, this scientific basis needs to be advanced and evolved with ecosystems exp...
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- 2021
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21. Introduction to the NOAA Integrated Ecosystem Assessment Program: Advancing Ecosystem Based Management
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Mark E. Monaco, Christopher R. Kelble, Ellen Spooner, S. A. Oakes, and Chris J. Harvey
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0106 biological sciences ,Resource (biology) ,010504 meteorology & atmospheric sciences ,business.industry ,010604 marine biology & hydrobiology ,Environmental resource management ,Ecosystem assessment ,01 natural sciences ,Ecosystem-based management ,ComputingMilieux_GENERAL ,Management strategy ,Community of practice ,Environmental Chemistry ,Ecosystem ,business ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,General Environmental Science - Abstract
In the marine science community of practice, the concept of ecosystem-based management (EBM) is a management strategy that incorporates the entire ecosystem, including humans, into resource managem...
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22. Optical-coherence tomography angiography and ultrawide-field angiography findings in eyes with refractory macular edema secondary to retinal vein occlusion switched to aflibercept: A subanalysis from a 48-week prospective study
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Kimberly Spooner, Thomas Hong, Andrew Chang, and Samantha Fraser-Bell
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medicine.medical_specialty ,Retinal Vein ,genetic structures ,Refractory ,Occlusion ,medicine ,anti-vascular endothelial growth factor ,Prospective cohort study ,Macular edema ,Aflibercept ,macular edema ,medicine.diagnostic_test ,business.industry ,aflibercept ,Optical coherence tomography angiography ,RE1-994 ,medicine.disease ,eye diseases ,Ophthalmology ,retinal vein occlusion ,Angiography ,Original Article ,Radiology ,sense organs ,recalcitrant ,business ,medicine.drug - Abstract
PURPOSE: To evaluate anatomical changes on ultra-wide-field fluorescein-angiography and optical coherence angiography (OCT-A) among a cohort with treatment-resistant macular edema secondary to retinal vein occlusions (RVO) switched to aflibercept. MATERIALS AND METHODS: Patients with persistent macular edema despite previous bevacizumab and/or ranibizumab were switched to aflibercept in a 48-week prospective trial. Ultra-wide-field fluorescein angiography (UWFFA) and OCT-A were performed at baseline, week-24 and week-48. The ischemic index was calculated from UWFFA and the areas of vascular perfusion. The foveal avascular zone (FAZ) were quantitatively evaluated on OCT-A. RESULTS: Eighteen patients (mean age, 70.3±8.6 years) were recruited. Mean central macular thickness (CMT) was significantly reduced at 48-weeks compared to baseline (-87.6±48.8 μm, P < 0.001 and -191.0±128.3μm, P < 0.001 among BRVO and CRVO eyes, respectively). The mean baseline ischemic index as measured on Optos wide-field angiography was 10.9%±8.3 and decreased to 5.7%±4.2 (P = 0.028), at week 48. The mean FAZ areas of the SCP and DCP reduced by -0.06 ± 0.12 mm 2 and -0.17± 0.45 mm 2 , respectively. FAZ area on OCT-A was stable in eyes with stable or improved vision but increased in size in eyes with baseline macular ischemia and those with lower gains in BCVA at week 48 (R 2 =0.719, P = 0.05 and R 2 =0.516, P = 0.01). CONCLUSION: There was a reduction in macular edema measured on OCT at 48-weeks in eyes switched to aflibercept with chronic macular edema due to retinal vein occlusion. There was also a reduction in retinal ischemia as measured using UWFFA.
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23. Macular Atrophy Incidence and Progression in Eyes with Neovascular Age-Related Macular Degeneration Treated with Vascular Endothelial Growth Factor Inhibitors Using a Treat-and-Extend or a Pro Re Nata Regimen
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Andrew Chang, Kimberly Spooner, Mariano Cozzi, Marion R. Munk, Samantha Fraser-Bell, Alessandro Invernizzi, Thomas Hong, Davide Monteduro, and Giovanni Staurenghi
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0303 health sciences ,medicine.medical_specialty ,genetic structures ,biology ,business.industry ,VEGF receptors ,Incidence (epidemiology) ,Hazard ratio ,Macular atrophy ,Macular degeneration ,Treat and extend ,medicine.disease ,eye diseases ,03 medical and health sciences ,Ophthalmology ,Regimen ,0302 clinical medicine ,Pro re nata ,030221 ophthalmology & optometry ,biology.protein ,medicine ,sense organs ,business ,030304 developmental biology - Abstract
Purpose To compare the incidence and progression of macular atrophy (MA) in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) agents using either a treat-and-extend (T&E) or a pro-re-nata (PRN) regimen over 4-years in a real-life setting. Design 4-year, multicenter, retrospective comparative study PARTICIPANTS: 264 patients with treatment-naive nAMD. Methods Consecutive patients with nAMD received anti-VEGF therapy according to a T&E (n=163) or PRN (n=101) regimen. Eyes were included if they had received anti-VEGF injections for a period of at least 4-years and had annual fundus autofluorescence (FAF) and optical coherence tomography (OCT) imaging using Heidelberg Spectralis. Two masked graders independently delineated areas of MA from serial FAF images using Heidelberg region finder software, and growth rates were calculated. Incident MA was assessed using proportional hazard ratios. Main outcomes measures MA incidence and progression over 4-years, association between treatment strategy, and number of injections. Results At baseline, MA was present in 24% and 20% of study eyes in T&E and PRN groups, respectively (p=0.32). At year-4, 27% (34/124) and 25% (20/81) eyes without baseline MA had detectable MA, in the T&E and PRN groups respectively. In those with MA at baseline, the mean square root area of MA progressed by a rate of 0.4±0.2 and 0.4±0.1mm/year in the T&E and PRN groups, respectively (p=0. 23). Multivariate analysis for baseline predictors of MA growth demonstrated older age, poorer baseline VA and presence of RAP, had a higher risk of greater MA progression (P=0.03). Regression analysis demonstrated no association between T&E and PRN treatment strategies with the risk of developing new MA during the four years of follow-up or the progression of pre-existing MA at year-4 (p=0.692). Conclusion Over four years, neither incidence nor progression of macular atrophy in eyes with nAMD treated with anti-VEGF injections was influenced by the treatment regimen and injection frequency. Eyes treated with a T&E regimen received more injections and had better visual outcomes compared to those treated with a PRN approach.
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24. The influence of whole-body vibration on heart rate, stride length, and bone mineral content in the mature exercising horse
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R.M. Hoffman, K. Maher, J.C. Haffner, and H.S. Spooner
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medicine.medical_specialty ,040301 veterinary sciences ,Physiology ,business.industry ,Veterinary (miscellaneous) ,Endocrinology, Diabetes and Metabolism ,Biophysics ,Horse ,030209 endocrinology & metabolism ,04 agricultural and veterinary sciences ,Stride length ,Biochemistry ,0403 veterinary science ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Physiology (medical) ,Heart rate ,Bone mineral content ,Medicine ,Whole body vibration ,Orthopedics and Sports Medicine ,business - Abstract
Research in humans suggests whole-body vibration (WBV) aids in maintaining bone mineral content (BMC) yet results in the horse are less favourable. Anecdotally, WBV is reported to reduce pain and improve performance. This study was designed to test the effect of WBV on exercising horses, hypothesising that WBV would lower heart rate (HR) during treatment, increase BMC, modify markers of bone metabolism, and increase stride length. Eleven horses were randomly assigned into control (CON, n=5) or WBV (VIB, n=6) groups for a 28-day treatment period. Both groups exercised for 1 h, 6 d/wk on a mechanical exerciser. VIB horses received 50 Hz WBV for 45 min, 5 days/wk. Third metacarpal radiographs were taken at 0 and 28 days, and BMC determined via radiographic bone aluminium equivalence (RBAE). Blood samples taken at day 0 and 28 were analysed for serum pyridinoline cross-links (PYD) and osteocalcin (OC). Heart rate was analysed on day 23 for 4 horses per group. Stride length was determined while trotting in hand on day 0 and 28. No influence of WBV on RBAE of any bone cortices, PYD or OC was observed (P>0.10); stride length was also unaffected (P=0.88). A period effect was observed for a decrease in RBAE of the lateral cortex (P=0.01), and a trend towards a decrease was noted in total density (P=0.05), likely an effect of stalling. Compared to baseline, ΔHR declined during treatment (P=0.06) in VIB (-4.8±2.8 bpm) compared to control CON (3.0±2.8 bpm). The results suggest, in normal exercising horses, WBV does not increase BMC, influence markers of bone metabolism, or increase stride length.
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25. Comparison of A(H3N2) Neutralizing Antibody Responses Elicited by 2018–2019 Season Quadrivalent Influenza Vaccines Derived from Eggs, Cells, and Recombinant Hemagglutinin
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Wei Wang, Ryan C. Maves, Christian L. Coles, Min Z. Levine, Srihari Seshadri, Esmeralda Alvarado-Facundo, Carol D. Weiss, Bruce M. McClenathan, David Hrncir, Stephanie A Richard, Limone Collins, Christina Spooner, Tahaniyat Lalani, Timothy Burgess, Gregory Utz, Anuradha Ganesan, Rhonda E Colombo, Casey Geaney, Ana E Markelz, Tyler E. Warkentien, Christina Schofield, Katrin Mende, Russell Vassell, and Maryna C. Eichelberger
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Adult ,0301 basic medicine ,Microbiology (medical) ,Influenza vaccine ,Hemagglutinin (influenza) ,Hemagglutinin Glycoproteins, Influenza Virus ,Antibodies, Viral ,Neutralization ,Antigenic drift ,03 medical and health sciences ,0302 clinical medicine ,Influenza, Human ,Humans ,Medicine ,030212 general & internal medicine ,Seroconversion ,Neutralizing antibody ,biology ,business.industry ,Influenza A Virus, H3N2 Subtype ,Immunogenicity ,Antibodies, Neutralizing ,Virology ,Vaccination ,Hemagglutinins ,030104 developmental biology ,Infectious Diseases ,Influenza Vaccines ,biology.protein ,Seasons ,business - Abstract
Background Low vaccine effectiveness against A(H3N2) influenza in seasons with little antigenic drift has been attributed to substitutions in hemagglutinin (HA) acquired during vaccine virus propagation in eggs. Clinical trials comparing recombinant HA vaccine (rHA) and cell-derived inactivated influenza vaccine (IIV) to egg-derived IIVs provide opportunities to assess how egg-adaptive substitutions influence HA immunogenicity. Methods Neutralization titers in pre- and postimmunization sera from 133 adults immunized with 1 of 3 types of influenza vaccines in a randomized, open-label trial during the 2018–2019 influenza season were measured against egg- and cell-derived A/Singapore/INFIMH-16-0019/2016-like and circulating A(H3N2) influenza viruses using HA pseudoviruses. Results All vaccines elicited neutralizing antibodies to all H3 vaccine antigens, but the rHA vaccine elicited the highest titers and seroconversion rates against all strains tested. Egg- and cell-derived IIVs elicited responses similar to each other. Preimmunization titers against H3 HA pseudoviruses containing egg-adaptive substitutions T160K and L194P were high, but lower against H3 HA pseudoviruses without those substitutions. All vaccines boosted neutralization titers against HA pseudoviruses with egg-adaptive substitutions, but poorly neutralized wild-type 2019–2020 A/Kansas/14/2017 (H3N2) HA pseudoviruses. Conclusion Egg- and cell-derived 2018–2019 season influenza vaccines elicited similar neutralization titers and response rates, indicating that the cell-derived vaccine did not improve immunogenicity against the A(H3N2) viruses. The higher responses after rHA vaccination may be due to its higher HA content. All vaccines boosted titers to HA with egg-adaptive substitutions, suggesting boosting from past antigens or better exposure of HA epitopes. Studies comparing immunogenicity and effectiveness of different influenza vaccines across many seasons are needed.
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26. Trends and Racial/Ethnic Disparities in the Rates of Pre-eclampsia by HIV Status in the US
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Vidella Coker, Muktar H. Aliyu, Hamisu M. Salihu, Collins Onyenaka, Jason L. Salemi, Deepa Dongarwar, Charlee King, Emmanuella Oduguwa, Jamalena Thompson, Oluwatoyin Bakare, Kiara K. Spooner, Omonike A. Olaleye, Sumaya Gendra, Seun Kutse, Elza Enamorado, Veronica B Ajewole, Onyinye Nwangwu, and Mayra Blanco
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Adult ,medicine.medical_specialty ,Health (social science) ,Adolescent ,Databases, Factual ,Sociology and Political Science ,Ethnic group ,HIV Infections ,Preeclampsia ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pre-Eclampsia ,Acquired immunodeficiency syndrome (AIDS) ,Pregnancy ,Epidemiology ,Ethnicity ,medicine ,Humans ,030212 general & internal medicine ,Pregnancy Complications, Infectious ,reproductive and urinary physiology ,Retrospective Studies ,030505 public health ,Eclampsia ,business.industry ,Health Policy ,Racial Groups ,Public Health, Environmental and Occupational Health ,Health Status Disparities ,Middle Aged ,medicine.disease ,United States ,female genital diseases and pregnancy complications ,Anthropology ,embryonic structures ,Cohort ,Female ,Hiv status ,0305 other medical science ,business ,Demography - Abstract
Preeclampsia and HIV account for a significant proportion of the global burden of disease and pose severe maternal–fetal risks. There is a dearth of literature regarding racial/ethnic disparities in preeclampsia associated with HIV/AIDS in the US. We retrospectively analyzed data from the National Inpatient Sample (NIS) database from 2002 to 2015 on a cohort of hospitalized pregnant women with or without preeclampsia and HIV. Joinpoint regression models were used to identify trends in the rates of preeclampsia among pregnant women living with or without HIV, stratified by race/ethnicity over the study period. We also assessed the association between preeclampsia and various socio-demographic factors. We analyzed over 60 million pregnancy-related hospitalizations, of which 3665 had diagnoses of preeclampsia and HIV, corresponding to a rate of 0.61 per 10,000. There was an increasing trend in the diagnosis of preeclampsia among hospitalized, pregnant women without HIV across each racial/ethnic category. The highest prevalence of preeclampsia was among non-Hispanic (NH) Blacks, regardless of HIV status. The increase in rates of pre-eclampsia between 2002 and 2015 was mostly noted among pregnant women without HIV. Regardless of HIV status, NH-Blacks experienced the highest discharge prevalence of preeclampsia.
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27. Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
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Graeme J. Hankey, Maree L. Hackett, Osvaldo P. Almeida, Leon Flicker, Gillian E. Mead, Martin S. Dennis, Christopher Etherton-Beer, Andrew H. Ford, Laurent Billot, Stephen Jan, Thomas Lung, Veronica Murray, Erik Lundström, Craig S. Anderson, Robert Herbert, Gregory Carter, Geoffrey A. Donnan, Huy-Thang Nguyen, John Gommans, Qilong Yi, Qiang Li, Severine Bompoint, Sarah Barrett, Anne Claxton, Julia O'Dea, Michelle Tang, Clare Williams, Shenae Peterson, Christie Drummond, Uyen-Ha Hong, Linh-Thi My Le, Tram-Thi Bich Ngo, Yen-Bao Mai, Huyen-Thanh Han, Nhu-Quynh Truong, Huong-Thi Nguyen, Hai-Thanh Ngo, Thi Binh Nguyen, Oanh-Thi Kieu Ha, Trang-Le Huyen Nguyen, Richard I. Lindley, Peter New, Andrew Lee, Thanh-Trung Tran, Loan-Tran Truc Mai Le, Thuy-Le Vu Kieu, Sang-Van Nguyen, Thuy-Anh Diem Nguyen, Tam-Nhat Dang, Hanh-Thi Truc Phan, Loan-Thi Ngoc Vo, Mai-Hue Nguyen, Hanh-Cao Dang, Hong-Thi Tran, Linh-Thi Cam Dam, Trinh-Thi Kim Ngo, Thai-Nguyen Thanh Pham, Binh-Nguyen Pham, Nha-Thi Thanh Dao, Huong-Thi Bich Nguyen, Linh-Thi Cam Le, Chi-Minh Do, Huy-Quoc Huynh, Giau-Thi Kim Tran, Oanh-Thi Le, Ly-Thi Khanh Tran, Chinh-Dinh Duong, Duong-Van Kieu, Na Le, Hoa-Ngoc Nguyen, Binh-Van Le, Long-Thanh Nguyen, Long-Van Nguyen, Tuan-Quoc Dinh, Tan-Van Vo, Tram-Ngoc Bui, Uyen-Thi To Hoang, Hien-Thi Bich Nguyen, Ha-Thi Thu Nguyen, Nga-Thuy Lam, Khanh-Kim Le, Phuong-Thanh Trinh, Hop-Quang Huynh, Thao-Thi Thu Nguyen, Huyen-Ngoc Lu, Tham-Hong Pham, Sam-Hoanh Nguyen, Ninh-Hong Le, Giang-Truong Nguyen, Bich-Thi Doan, Sung-Phuoc Pham, Duong-Huu Luong, Ha-Van Mai, Thuc-Van Tran, Phuong-Thi Do, Hoai-Thi Le, Chi-Van Nguyen, Phuong-Doan Nguyen, Ton-Duy Mai, Phuong-Viet Dao, Dung-Tien Nguyen, Dai-Quoc Khuong, Trung-Xuan Vuong, Lan-Tuong Vu, Ngoc-Duc Ngo, Hanh-Hong Dang, Phuong-Thai Truong, Ngan-Thi Le, Hoa-Van Hoang, Chung-Quang Do, Minh-Thao Nguyen, Anh-Hai Dam, Quynh-Nhu Le, Ngoc-Hoang Nguyen, Tuyen-Van Nguyen, Toan-Dinh Le, Ha-Thi Hai Dinh, Cuong-Van Pham, Khanh-Thi Ngoc Thach, Linh-Hai Nguyen, Loan-Thi Nguyen, Vien-Chi Le, Phuong-Hong Tran, Tai-Anh Nguyen, Tuan-Van Le, Luyen-Van Truong, Tue-Chau Bui, Ngoc-Xuan Huynh, Lap-Van Dinh, An-Gia Pham, Trang-Thi Huyen Le, Vy-Tuong Nguyen, Yen-Hai Nguyen, Thang-Ba Nguyen, Huy Thai, Quyen-Thi Ngoc Pham, Khoa-Duy Dao, Quoc-Nguyen Bao Pham, Thuong-Thi Huyen Dang, Huong-Huynh To Dinh, Trang-Mai Tong, Thuy-Thi Vu, Si-Tri Le, Tai-Ngoc Tran, Phuong-Hoai Tran, Ngoc-Thuy Nhu Dinh, Binh-Thanh Nguyen, Vinh-Phuong Do, Anh-Ngoc Nguyen, Binh-Thi Thanh Nguyen, David Blacker, Lindsey Bunce, Ai Ling Tan, Darshan Ghia, Gillian Edmonds, Nicole O'Loughlin, Megan Ewing, Kerri-Ann Whittaker, Lorralee Deane, Yash Gawarikar, Brett Jones, Maria Lopez, Koushik Nagesh, Emma Siracusa, Stephen Davis, Amy McDonald, Jess Tsoleridis, Rachael McCoy, David Jackson, Gab Silver, Timothy R. Bates, Amanda Boudville, Lynda Southwell, Dennis Cordato, Alan J. McDougall, Cecilia Cappelen-Smith, Zeljka Calic, Shabeel Askar, Qi Cheng, Raymond Kumar, Richard Geraghty, Maree Duroux, Megan Ratcliffe, Samantha Shone, Cassandra McLennan, Ramesh Sahathevan, Casey Hair, Stanley Levy, Beverley Macdonald, Benjamin Nham, Louise Rigney, Dev Nathani, Sumana Gopinath, Vishal Patel, Abul Mamun, Benjamin Trewin, Chun Phua, Ho Choong, Lauren Tarrant, Kerry Boyle, Luisa Hewitt, Monique Hourn, Amanda Masterson, Kim Oakley, Karen Ruddell, Colette Sanctuary, Kimberley Veitch, Camelia Burdusel, Lina Lee, Gary Cheuk, Jeremy Christley, Tabitha Hartwell, Craig Davenport, Kate Hickey, Rosanna Robertson, Michelle Carr, Sam Akbari, Hannah Coyle, Megan O'Neill, Cameron Redpath, Caroline Roberts, Marjan Tabesh, Toni Withiel, Kapila Abeysuriya, Andrew Granger, Angela Abraham, Chermaine Chua, Dung Do Nguyen, Vathani Surendran, Melissa Daines, David Shivlal, Mudassar Latif, Noreen Mughal, Patricia Morgan, Martin Krause, Miriam Priglinger, Ehsan E. Shandiz, Susan Day, Lay Kho, Michael Pollack, Judith Dunne, Helen Baines, Merridie Rees, Jenni White, Aicuratiya Withanage, Candice Delcourt, Cheryl Carcel, Alejandra Malavera, Amy Kunchok, Elizabeth Ray, Elizabeth Pepper, Emily Duckett, Sally Ormond, Andrew Moey, Timothy Kleinig, Vanessa Maxwell, Chantal Baldwin, Wilson Vallat, Deborah Field, Romesh Markus, Kirsty Page, Danielle Wheelwright, Sam Bolitho, Steven Faux, Fix Sangvatanakul, Alexis Brown, Susan Walker, Jennifer Massey, Hillary Hayes, Pesi Katrak, Annie Winker, Alessandro Zagami, Alanah Bailey, Sarah Mccormack, Andrew Murray, Mark Rollason, Christopher Taylor, Fintan O'Rourke, Ye Min Kuang, Heike Burnet, Yvonne Liu, Aileen Wu, Diana Ramirez, Tissa Wijeratne, Sherisse Celestino, Essie Low, Cynthia Chen, Jennifer Bergqvist, Andrew Evans, Queenie Leung, Martin Jude, Rachael McQueen, Katherine Mohr, Latitia Kernaghan, Paul Stockle, Boon L. Tan, Sara Laubscher, Diana Schmid, Melissa Spooner, Bhavesh Lallu, Bronwen Pepperell, John Chalissery, Karim Mahawish, Susan DeCaigney, Paula Broughton, Karen Knight, Veronica Duque, Harry McNaughton, Jeremy Lanford, Vivian Fu, and Lai-Kin Wong
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Population ,Placebo-controlled study ,Placebo ,03 medical and health sciences ,0302 clinical medicine ,Double-Blind Method ,Modified Rankin Scale ,Fluoxetine ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,education ,Stroke ,Aged ,education.field_of_study ,business.industry ,B790 ,Recovery of Function ,Odds ratio ,Middle Aged ,medicine.disease ,Clinical trial ,Treatment Outcome ,Female ,Neurology (clinical) ,Stroke recovery ,business ,Selective Serotonin Reuptake Inhibitors ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
Background: Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population.Methods: AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921.Findings: Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [Interpretation: Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke.Funding: National Health and Medical Research Council of Australia.
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28. Resurrecting place: Visual representation and the poetic imagination
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Thomas Spooner
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Literature ,Phenomenology (philosophy) ,Poetry ,business.industry ,media_common.quotation_subject ,Representation (arts) ,Art ,business ,Romanticism ,Postmodernism ,media_common - Abstract
With reference to an ongoing practice-based project, illustration in this article is considered for its capacity as an authorial practice able to complement and communicate ideas emanating from academic research. This article discusses the phenomenon of ‘place’, specifically, place as a lived concrete site comprising both physical and emotional phenomena and culminating in a meaningful experience of ‘being-in-the-world’. With particular reference to more marginal settings of everyday public experience, this article argues that as a result of current cultural phenomena relating to the economic and practical necessities of daily action, and historical developments in western thinking, place is an idea that is commonly obscured from daily experience. Through the teachings of phenomenology and early German romanticism, this article explores ideas that, through visual representation, meaningful notions of place can be resuscitated and transmitted between the illustrator and viewer. Further, through discussion of ideas emerging from postmodernism, conditions that affect our experience and expectations of place in the present are also addressed. Whilst place as a lived and meaningful totality is invariably informed by structures of subjectivity, visual representation is considered here, for its usefulness in appealing to meaningful, poetic dimensions of wider human experience.
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29. Hidden Phenomena During Transient Reaction Trajectories in Liquid Metals Processing
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Zushu Li, Seetharaman Sridhar, and Stephen Spooner
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Liquid metal ,Ladle ,Materials science ,Decarburization ,business.industry ,TN ,Metals and Alloys ,Nucleation ,Condensed Matter Physics ,TS ,Chemical reaction ,Steelmaking ,Continuous casting ,TA ,Mechanics of Materials ,Chemical physics ,Materials Chemistry ,business ,Order of magnitude - Abstract
The transient trajectory taken for a system striving toward equilibration has consequences on the rate of processes and on the chemical and physical state of products in metallurgical processes. A case study approach to recent advancements in liquid steel processing is given. A combination of techniques and knowledge developed is given as a targeted showcase of the authors’ contributions to the understanding of liquid metal droplet reactions and their contribution to the large-scale production processes within the steel industry. Examples relevant to novel ironmaking technologies, oxygen steelmaking, ladle metallurgy, and continuous casting are discussed, showing the range of processes that benefit from greater understanding in this area. This article considers specifically the reaction of liquid ferrous droplets, immersed in molten oxides, involving key alloying components, including phosphorus, aluminum, and carbon. The studies use high-temperature–confocal scanning laser microscopy (HT-CSLM), X-ray computed tomography (XCT), phase-field modeling, and in situ limited angle X-ray imaging. These techniques have seen significant development over recent years, and the combination of these powerful tools reveals the occurrence of spontaneous emulsification driven by chemical reaction (in the case of oxygen/phosphorus/aluminum reactions) and gas-phase formation (in the case of decarburization) both internally and externally to a steel droplet. A key finding is that the interfacial area pertinent for the heterogenous reactions to occur changes considerably (by up to an order of magnitude) depending on the chemical driving force. Additional key findings include the shift between preferential internal and external gas nucleation during decarburization, an inflection point of behavior as to whether or not spontaneous emulsification will occur (within the study discussed, this is between 3 and 4 wt pct Al) and the pathway of perturbation growth through which spontaneous emulsification occurs, including the physical maxima a perturbation will grow to before breaking away from the parent droplet.
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30. Prefrontal Multielectrode Transcranial Direct Current Stimulation Modulates Performance and Neural Activity Serving Visuospatial Processing
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Tony W. Wilson, Michael T Rezich, Elizabeth Heinrichs-Graham, Alex I. Wiesman, Amy L. Proskovec, Yasra Arif, and Rachel K. Spooner
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Adult ,Male ,Cognitive Neuroscience ,medicine.medical_treatment ,Stimulation ,Transcranial Direct Current Stimulation ,computer.software_genre ,behavioral disciplines and activities ,Functional Laterality ,Cellular and Molecular Neuroscience ,Neural activity ,Dorsolateral Prefrontal Cortex ,Voxel ,Humans ,Medicine ,Attention ,Transcranial direct-current stimulation ,medicine.diagnostic_test ,business.industry ,Magnetoencephalography ,Dorsolateral prefrontal cortex ,Occipital Cortices ,medicine.anatomical_structure ,Laterality ,Female ,Original Article ,business ,computer ,Neuroscience - Abstract
The dorsolateral prefrontal cortex (DLPFC) is known to play a critical role in visuospatial attention and processing, but the relative contribution of the left versus right DLPFC remains poorly understood. We applied multielectrode transcranial direct-current stimulation (ME-tDCS) to the left and right DLPFC to investigate its net impact on behavioral performance and population-level neural activity. The primary hypothesis was that significant laterality effects would be observed in regard to behavior and neural oscillations. Twenty-five healthy adults underwent three visits (left, right, and sham ME-tDCS). Following stimulation, participants completed a visuospatial processing task during magnetoencephalography (MEG). Statistically significant oscillatory events were imaged, and time series were then extracted from the peak voxels of each response. Behavioral findings indicated differences in reaction time and accuracy, with left DLPFC stimulation being associated with slower responses and decreased accuracy compared to right stimulation. Left DLPFC stimulation was also associated with increases in spontaneous theta and decreases in gamma within occipital cortices relative to both right and sham stimulation, while connectivity among DLPFC and visual cortices was generally increased contralateral to stimulation. These data suggest spectrally specific modulation of spontaneous cortical activity at the network-level by ME-tDCS, with distinct outcomes based on the laterality of stimulation.
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31. Quality of life after breast-conserving therapy and adjuvant radiotherapy for non-low-risk ductal carcinoma in situ (BIG 3-07/TROG 07.01): 2-year results of a randomised, controlled, phase 3 trial
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Madeleine T King, Emma K Link, Tim J Whelan, Ivo A Olivotto, Ian Kunkler, Antonia Helen Westenberg, Guenther Gruber, Penny Schofield, Boon H Chua, Claire Phillips, Guy Bryant, Helen Westenberg, Om Pra-Kesh Purohit, Verity Ahern, Peter Graham, Mohamed Akra, Orla McArdle, Peter O'Brien, Jane Ludbrook, Jennifer Harvey, John H Maduro, Isabelle Gabelle-Flandin, Carine Kirkove, Carolyn Bedi, Joseph Martin, Tony Vu, Theirry Muanza, Anthony Neal, Adel Courdi, Juliette Thariat, Eileen Rakovitch, Laurien Daniels, Marjan van Hezewijk, Wlasyslawa Cwajna, Adelheid Roelstraete, Angela van Baardwijk, Nicola Russel, Anne Koch, Jennifer Croke, Imogen Locke, Peter Jeal, Quenten Walker, Kandeepeepan Thuraisingham, Anupam Chauduri, David Joseph, Mandy Taylor, Sabine Vanderkam, Tony Woo, Johann Tang, Michael Yassa, Elaine Wai, Susan Hewitt, Shazia Mahmood, Jennifer Gilmore, Bolante Ofi, Amit Bahl, Olga Vujovic, Edward Yu, Duc Le, Iwa Kong, Alan Nichol, Nina Bijker, Geoff Delaney, Malcolm Feigen, Adeline Lim, Michael Chao, Margaret Latham, Hafiz Algurafi, Christoph Tausch, Eric Khoo, Sam Leung, Karen Taylor, Sasha Senthi, Andrea Stevens, Abhro Chaudhuri, Susan Cleator, Adrian Murray Brunt, Scott Babington, David Christie, Daniel Zwahlen, Ulrich Schratzenstaller, Laurence Masson, Nicola Storey, Eshwar Kumar, Liz Sherwin, Reinhilde Weytjens, Sharma Ravi, Patricia Lawton, Ruth Angell, Glenys Round, Angela Allen, Ziad Thotathil, Margaret Anthes, Christiane Reuter, Laura Pettit, Yvonne Zissiadis, Christine Elder, Antoinette Verbeek-de Kanter, Andree Lirette, Ludwig Plasswilm, David Spooner, Fiona Hoar, Islam Mohamed, Kristina Lossl, Vivienne Loo, Antonella Richetti, Tamasin Evans, Aisling Hennessy, Medhat El-Mallah, Marketa Skala, Raef Awad, Isabelle Germain, Carine Mitine, Hilde Van Parijs, Mark Churn, Nawaz Walji, Michael Francis, Karin Stellamans, Gunther Gruber, Giovanni Ivaldi, Abdulla Alhasso, Lizbeth Kenny, Ken Tiver, Matthew Griffin, Gillian Lamoury, Marco Trovo, Hafiz Algufarfi, Minjae Lah, Scott Carruthers, George Papadatos, Gabriel Paardekooper, Mojca Persic, Bernadette Lavery, Radiotherapy, and CCA - Cancer Treatment and Quality of Life
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Oncology ,medicine.medical_specialty ,medicine.medical_treatment ,Breast surgery ,Brachytherapy ,Breast Neoplasms ,Mastectomy, Segmental ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Randomized controlled trial ,law ,Internal medicine ,medicine ,Clinical endpoint ,Humans ,Breast ,030212 general & internal medicine ,Neoplasm Staging ,Intention-to-treat analysis ,business.industry ,Middle Aged ,medicine.disease ,Radiation therapy ,Carcinoma, Intraductal, Noninfiltrating ,Treatment Outcome ,030220 oncology & carcinogenesis ,Quality of Life ,Female ,Radiotherapy, Adjuvant ,Neoplasm Recurrence, Local ,business ,Mastectomy - Abstract
Summary Background BIG 3-07/TROG 07.01 is an international, multicentre, randomised, controlled, phase 3 trial evaluating tumour bed boost and hypofractionation in patients with non-low-risk ductal carcinoma in situ following breast-conserving surgery and whole breast radiotherapy. Here, we report the effects of diagnosis and treatment on health-related quality of life (HRQOL) at 2 years. Methods The BIG 3-07/TROG 07.01 trial is ongoing at 118 hospitals in 11 countries. Women aged 18 years or older with completely excised non-low-risk ductal carcinoma in situ were randomly assigned, by use of a minimisation algorithm, to tumour bed boost or no tumour bed boost, following conventional whole breast radiotherapy or hypofractionated whole breast radiotherapy using one of three randomisation categories. Category A was a 4-arm randomisation of tumour bed boost versus no boost following conventional whole breast radiotherapy (50 Gy in 25 fractions over 5 weeks) versus hypofractionated whole breast radiotherapy (42·5 Gy in 16 fractions over 3·5 weeks). Category B was a 2-arm randomisation between tumour bed boost versus no boost following conventional whole breast radiotherapy, and category C was a 2-arm randomisation between tumour bed boost versus no boost following hypofractionated whole breast radiotherapy. Stratification factors were age at diagnosis, planned endocrine therapy, and treating centre. The primary endpoint, time to local recurrence, will be reported when participants have completed 5 years of follow-up. The HRQOL statistical analysis plan prespecified eight aspects of HRQOL, assessed by four questionnaires at baseline, end of treatment, and at 6, 12, and 24 months after radiotherapy: fatigue and physical functioning (EORTC QLQ-C30); cosmetic status, breast-specific symptoms, arm and shoulder functional status (Breast Cancer Treatment Outcome Scale); body image and sexuality (Body Image Scale); and perceived risk of invasive breast cancer (Cancer Worry Scale and a study-specific question). For each of these measures, tumour bed boost was compared with no boost, and conventional whole breast radiotherapy compared with hypofractionated whole breast radiotherapy, by use of generalised estimating equation models. Analyses were by intention to treat, with Hochberg adjustment for multiple testing. This trial is registered with ClinicalTrials.gov , NCT00470236 . Findings Between June 1, 2007, and Aug 14, 2013, 1208 women were enrolled and randomly assigned to receive no tumour bed boost (n=605) or tumour bed boost (n=603). 396 of 1208 women were assigned to category A: conventional whole breast radiotherapy with tumour bed boost (n=100) or no boost (n=98), or to hypofractionated whole breast radiotherapy with tumour bed boost (n=98) or no boost (n=100). 447 were assigned to category B: conventional whole breast radiotherapy with tumour bed boost (n=223) or no boost (n=224). 365 were assigned to category C: hypofractionated whole breast radiotherapy with tumour bed boost (n=182) or no boost (n=183). All patients were followed up at 2 years for the HRQOL analysis. 1098 (91%) of 1208 patients received their allocated treatment, and most completed their scheduled HRQOL assessments (1147 [95%] of 1208 at baseline; 988 [87%] of 1141 at 2 years). Cosmetic status was worse with tumour bed boost than with no boost across all timepoints (difference 0·10 [95% CI 0·05–0·15], global p=0·00014, Hochberg-adjusted p=0·0016); at the end of treatment, the estimated difference between tumour bed boost and no boost was 0·13 (95% CI 0·06–0·20; p=0·00021), persisting at 24 months (0·13 [0·06–0·20]; p=0·00021). Arm and shoulder function was also adversely affected by tumour bed boost across all timepoints (0·08 [95% CI 0·03–0·13], global p=0·0033, Hochberg adjusted p=0·045); the difference between tumour bed boost and no boost at the end of treatment was 0·08 (0·01 to 0·15, p=0·021), and did not persist at 24 months (0·04 [–0·03 to 0·11], p=0·29). None of the other six prespecified aspects of HRQOL differed significantly after adjustment for multiple testing. Conventional whole breast radiotherapy was associated with worse body image than hypofractionated whole breast radiotherapy at the end of treatment (difference –1·10 [95% CI –1·79 to –0·42], p=0·0016). No significant differences were reported in the other PROs between conventional whole breast radiotherapy compared with hypofractionated whole breast radiotherapy. Interpretation Tumour bed boost was associated with persistent adverse effects on cosmetic status and arm and shoulder functional status, which might inform shared decision making while local recurrence analysis is pending. Funding National Health and Medical Research Council, Susan G Komen for the Cure, Breast Cancer Now, OncoSuisse, Dutch Cancer Society.
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32. Brolucizumab: an evolution in treatment for neovascular age-related macular degeneration
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Kimberly Spooner, Ee Lin Ong, Thomas Hong, and Andrew Chang
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Anti vegf ,medicine.medical_specialty ,genetic structures ,business.industry ,Angiogenesis ,Biomedical Engineering ,Macular degeneration ,medicine.disease ,eye diseases ,03 medical and health sciences ,Ophthalmology ,0302 clinical medicine ,Age related ,030221 ophthalmology & optometry ,medicine ,sense organs ,business ,030217 neurology & neurosurgery ,Optometry - Abstract
Introduction: The treatment paradigm for neovascular age-related macular degeneration (nAMD) has had a profound shift over the past 15 years with the advent of anti-vascular endothelial growth fact...
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33. Volume I. Introduction to DUNE
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E. Hazen, Armin Karcher, D. Smargianaki, Christopher L. Marshall, K. Spurgeon, M. Gold, C. Vignoli, C. J. Solano Salinas, M. J. Wilking, K. Kothekar, G. Sirri, Evgueni Goudzovski, H. Mendez, W. Flanagan, V. Papadimitriou, D. Redondo, S. R. Mishra, Y.-J. Jwa, G. Petrillo, M. Spanu, Xiaolu Ji, O. V. Mineev, M. Bishai, S. Menary, L. Molina Bueno, P. C. de Holanda, H. Berns, A. Gendotti, A. M. Szelc, R. Gandhi, A. Himmel, M. Rajaoalisoa, P. Bour, N. Kazaryan, L. Mualem, Gareth J. Barker, C. Cattadori, S. Ravat, W. Mu, D. Marfatia, T. Miedema, Kendall Mahn, Jorge Molina, Filippo Resnati, S. Magill, E. Niner, D. Autiero, Poonam Mehta, John Evans, J. S. Díaz, P. Novella, J. Fowler, G. Karagiorgi, S. J. M. Peeters, William J. Marciano, S. Bordoni, James Mueller, J. Martín-Albo, W. Fox, K. Grzelak, C. Hohl, R. Haenni, S. Alonso Monsalve, B. Howard, G. Ge, Alexander Tapper, Thomas Strauss, Silvia Pascoli, B. Stillwell, A. Lambert, A. Holin, K. V. Tsang, J. Maneira, R.A. Rameika, Juraj Bracinik, C. Wret, M. Tenti, Alberto Cervelli, Sukalyan Chattopadhyay, Laura Dominé, K. Herner, Hem Raj Sharma, S. Kasai, A. Higuera Pichardo, M. Betancourt, A. Scarff, R. Northrop, M. V. Diwan, D. J. Payne, C. Gotti, M. A. Vermeulen, R. M. Berner, J. J. De Vries, S. Shafaq, Yu. G. Kudenko, L. Pickering, B. Bhuyan, C. Kuruppu, Janet Conrad, D. Brailsford, R. Van Berg, J. Chaves, B. Paulos, R. Sipos, E. Pennacchio, F. W. Sippach, T. Li, S. Striganov, Laura Paulucci, S. Manly, P. Hamilton, R. G. Van de Water, R. Nandakumar, B. Szczerbinska, D. Cherdack, H. Carranza, Milos Lokajicek, K. Nishimura, E. Kearns, A. C. Ezeribe, J. Hoff, A. McNab, A. Stuart, G. Vasseur, C. Petta, M. Wetstein, M. M. Khabibullin, A. Bitadze, Yichen Li, G. Brunetti, L. Suter, L. Pasqualini, S. Martynenko, Ph. Lebrun, B. Morgan, L. Patrizii, A. Guglielmi, D. Wenman, S. C. Timm, R. Sharma, R. Saakyan, R. Gran, C. McGrew, C. Andreopoulos, A. Mann, F. Terranova, C. Cuesta, O. G. Miranda, C. Patrick, José W. F. Valle, A. Booth, G. Mandrioli, J. A. Nowak, S. Tufanli, R. Bajou, J. Urheim, J. Bian, Yasaman Farzan, M. Roda, J. G. Boissevain, J. Smolik, Thorsten Lux, L. Fields, D. Franco, S. P. Kasetti, M. Soares Nunes, A. Maddalena, M. Antonova, E. Kemp, N. Solomey, Laura Manenti, K. Francis, M. H. Shaevitz, N. Barros, C. Booth, I. Caro Terrazas, R. Itay, E. Ewart, R. J. Nichol, D. Totani, P. Snopok, M. Sorel, Kaushik De, M. Soderberg, A. C. Weber, Jonas Rademacker, E. Brianne, M. J. Rodriguez Alonso, T. Boschi, Sandhya Choubey, D. Montanari, Giorgio Riccobene, A. Mefodiev, M. A. Acero, A. Rappoldi, F. F. Wilson, Nektarios Benekos, Piera Sapienza, V. Savinov, P. Melas, Kenneth Long, Jianbei Liu, C. Mossey, Renato Potenza, M. Shamma, N. P. Samios, Y. Penichot, C. Bromberg, W. C. Louis, V. Paolone, V. Pec, J. Pillow, S. Vergani, S. Balasubramanian, B. Carlus, D. Boyden, Kam-Biu Luk, Simon Lin, Sofia Andringa, F. Jediny, K. Qi, K. Wood, M. Toups, Haleh Khani Hadavand, B. Tapia Oregui, G. P. Zeller, Gregory Iles, S. Gollapinni, A. Friedland, K. M. Heeger, P. Debbins, R. LaZur, J. A. B. Coelho, Jeremy Wolcott, Kevin J. Kelly, D. Sgalaberna, Joshua Barrow, John Marshall, M. Zito, K. Koehler, S. Pordes, P. Weatherly, E. D. Zimmerman, M. A. Leigui de Oliveira, N. Nayak, J. Sinclair, J. I. Crespo-Anadón, H. S. Chen, James John Brooke, A. Olivier, R. Milincic, P. Bernardini, Jim Freeman, L. Kashur, L.S. Rochester, Dario Gnani, Andrea Zani, M. Wallbank, Giuseppe Benedetto Cerati, T. Kosc, Dave Sankey, Patrick Green, Olga Mena, N. Martinez, F. Pietropaolo, S. Narita, A. Scaramelli, C. Grant, T. L. Usher, A. Marchionni, D. A. Dwyer, S. Prince, J. Haiston, T. J. Langford, A. M. Gago, Artur M. Ankowski, E. Gamberini, J. Asaadi, E. Valencia, Roberto Gutiérrez, T. Hasegawa, T. R. Junk, Y. A. Ramachers, D. A. Martinez Caicedo, R. Howell, R. M. de Almeida, Yasar Onel, Matheus Hostert, D. Duchesneau, J. A. Musser, F. Sergiampietri, D. W. Schmitz, E. Zhivun, Marzio Nessi, D. Lorca, Dave M Newbold, C. K. Jung, A. Olivares Del Campo, F. Krennrich, G. Testera, Alexandru Jipa, S. Rescia, Andrés Castillo, Joshua R. Klein, Olga Beltramello, Srubabati Goswami, Z. Williams, Vasundhara Singh, C. Mauger, J. Yu, M. Bonesini, Jack Fried, P. De Lurgio, C. A. Ternes, H. Y. Liao, K. Mason, N. Poonthottathil, A. Scarpelli, E. T. Worcester, J. T. Haigh, H. Muramatsu, G. C. Blazey, Rex Tayloe, R. Diurba, G. Christodoulou, F. Barao, S. Calvez, H. Duyang, L. M. Cremaldi, E. Motuk, H. Meyer, R. Guenette, C. Castromonte, A. Schukraft, Julián Félix, D. MacFarland, K. Gollwitzer, F. Varanini, Ranjan Dharmapalan, Lynn Wood, M. Pozzato, G. Zhu, S. Centro, Francesco Tortorici, S. Henry, R. A. Gomes, E. Gramellini, D. Vanegas Forero, Z. Pavlovic, D. A. Sanders, Christian Farnese, John F. Beacom, P. Vahle, G. A. Horton-Smith, T. Durkin, H. Y. Wei, L. Escudero Sanchez, Mingshui Chen, I. K. Furic, J. Moon, T. Young, John Matthews, E. James, B. Gelli, Gregory J. Michna, Steven Gardiner, P. Madigan, A. Izmaylov, D. Douglas, D. Gibin, M. Stancari, Shibaji Roy, I. Rakhno, J. Barranco Monarca, Paolo Calafiura, Q. David, Akitaka Ariga, Marvin L Marshak, Rukmani Mohanta, P. E. L. Clarke, C. Palomares, K. Cho, M. A. Arroyave, Andrew Norman, Claudia Brizzolari, J. Nachtman, Daniel Gastler, J. Hugon, M. Karolak, H. O. Back, Z. Ahmad, Gabriella Carini, M. Dabrowski, Paul Keener, Leigh H. Whitehead, Karol Hennessy, S. Söldner-Rembold, C. S. Lin, D. Edmunds, A. Chiriacescu, M. Oberling, T. Rehak, Katsuya Yonehara, T. E. Coan, L. V. Gomez Bermeo, F. Andrianala, Francesco Gonnella, T. Safford, E. Tatar, Utku Kose, M. Bhattacharjee, F. Cavanna, A. Muir, A. L. Renshaw, Orlando L. G. Peres, Amelia Maio, Carl Grace, J. Migenda, B. Viren, M. Muether, A. Mastbaum, Alfredo G. Cocco, C. Griffith, J. Mousseau, Paolo Carniti, L. Greenler, J. Rout, W. Ketchum, B. Radics, Ionel Lazanu, A. Laundrie, V. N. Solovov, David Cussans, X. Pons, N. Gallice, J. G. Learned, R. Flight, M. Nebot-Guinot, H. Vieira de Souza, S. Sacerdoti, J. Calcutt, K. Warburton, M. Nalbandyan, A. P. Furmanski, P. de Jong, B. T. Fleming, R. Poling, P.T. Smith, M. Worcester, Wei Wu, B. Guo, Frank Filthaut, J. Reichenbacher, S. Ventura, M. Graham, Riccardo Papaleo, A. M. Teklu, D. Newhart, P. Fernandez Menendez, J. Han, Deywis Moreno, C. Densham, Matthaeus Leitner, K. Fahey, Bindu A. Bambah, E. Blucher, S. Childress, T. Miao, Shiroman Prakash, Jason Kumar, Yi Chen, M. Kirby, P. Cotte, A. J. Roeth, R. Acciarri, E. Bechetoille, Gustaaf Brooijmans, K. Moffat, B. V. K. S. Potukuchi, S. Li, K. Vaziri, Sudarshan Paramesvaran, Seodong Shin, M. Santos-Maldonado, J.V. Dawson, Aldo Penzo, Ara Ioannisian, S. Rosauro-Alcaraz, H. T. Rakotondramanana, F. Piastra, N.V. Mokhov, S. Davini, R. L. Talaga, A. Caminata, G. Bellettini, J. Hartnell, C. Y. Chi, M. Groh, Karol Lang, C. Girerd, F. Diaz, F. Azfar, Alastair Grant, R. Hatcher, M. Zhao, J. Marteau, Irakli Lomidze, F. Stocker, T. Gamble, J. J. Grudzinski, L. Montaño Zetina, A. Heavey, Grzegorz Deptuch, F. Cavalier, R. Illingworth, I. Gil-Botella, N. Bostan, A. Gallego-Ros, T. Schaffer, N. Buchanan, G. Lehmann Miotto, Robert Shrock, J. Zennamo, Zviad Tsamalaidze, N. Mauri, H. da Motta, David Delepine, M. Torti, A. De Roeck, M. Calin, A. Lawrence, P. N. Ratoff, T. Kutter, B. Jargowsky, J. K. Nelson, Cari L. Johnson, C. S. Mishra, Vlastimil Kus, R.J. Staley, R. Cross, S. Murphy, S. Dennis, P. P. Koller, D. Whittington, D. Garcia-Gamez, K. Lande, R. B. Patterson, Anjan K. Giri, Wayne A. Barkhouse, A. Filkins, Daijin Kim, G.D. Barr, Junwei Huang, V. De Romeri, A. Mislivec, Manuela Campanelli, Y. Rigaut, Matthew L Strait, G. Barenboim, G. Prior, P. Guzowski, A. Cervera Villanueva, Robert Svoboda, C. Backhouse, A. Falcone, M. R. While, V. Bellini, C. Alt, J. Spitz, Stephen J. Parke, E. McCluskey, M. Mellinato, Jürgen Pozimski, D. Caratelli, L. Bellantoni, M. Rai, D. Mladenov, J. Stock, T. Lord, L. Zazueta, Alexander Deisting, R. Raboanary, T. Patzak, B. Rebel, M. D. Messier, B. Abi, A. de Gouvea, V. A. Kostelecky, K. Zeug, Joleen Pater, A. Hackenburg, K. Negishi, M. A. Hernandez Morquecho, J. Perry, Stephen Hillier, David H. Adams, D. Caiulo, S. Bolognesi, D. Belver, S. Zucchelli, F. Marinho, R. Petti, G.L. Raselli, Han Wang, Sergey A. Kulagin, A. Bashyal, J. Berger, A. Papanestis, A. Aurisano, F. Bay, Beatriz B. Siffert, E. Granados, B. Behera, H.E. Rogers, A. Rafique, J. Nesbit, Chris Brew, A. C. Kaboth, T. Vrba, P. Lasorak, Kim Siyeon, Andrea Dell'Acqua, Timothy M. Shaw, D. Braga, J. Ahmed, Yu. Onishchuk, Kate Scholberg, Alessandro Menegolli, T. Hamernik, Konstantinos Manolopoulos, R. K. Plunkett, V. Susic, Pedro A. N. Machado, T. Alion, N. Simos, O. Gogota, I. L. De Icaza Astiz, Narendra Sahu, F. Muheim, Ralf Lehnert, S. Gao, Andrew White, S. Berkman, André Rubbia, J. L. Raaf, J. Singh, C. Barnes, A. S. Hesam, S. D. Reitzner, T. Le, L. Hertel, R. Gandrajula, D. Vargas, L. Corwin, S. L. Mufson, B. J. P. Jones, C. Vilela, S. H. Kettell, B. Ramson, Chia-Chan Chang, P. Schlabach, C. Lastoria, Alan Watson, Z. Ghorbani-Moghaddam, Marcelo M. Guzzo, P. Baesso, S. Gwon, A. Surdo, Ina Sarcevic, Eric W. Hoppe, M. O. Wascko, T. A. Bolton, J. Greer, Y. T. Tsai, L. Camilleri, Sofia Vallecorsa, K. E. Duffy, S. Nagu, J. A. Maloney, Z. Vallari, J. Sensenig, L. Da Silva Peres, Manuel Alejandro Segura Delgado, A. Joglekar, M. P. Andrews, K. S. McFarland, C. T. Macias, D. Naples, Chao Zhang, D. M. DeMuth, Kazuhiro Terao, A. Paudel, M. Biassoni, D. Pershey, Rakesh Kumar, M. Bongrand, Michael Mulhearn, N. Moggi, E. Segreto, Xin Qian, Mafalda Dias, Claire Shepherd-Themistocleous, A. Chatterjee, S. Kohn, T. A. Mohayai, O.V. Dvornikov, L. Di Giulio, T. Yang, V. Zutshi, Sandeep Miryala, Enrique Calvo, V. Radeka, B. Bilki, I. Kadenko, D. Waters, D. Ruterbories, Antonino Sergi, M. Tzanov, C. Touramanis, F. Drielsma, Y. Xiao, A. Verdugo, J. M. Paley, Antonio Ereditato, C. E. Lane, M. J. Dolinski, C. Rubbia, A. Borkum, N. McConkey, J. Wang, X. Luo, Y. Karyotakis, M. Eads, S. Biagi, L. O. Arnold, J. J. Back, C. Morris, S. Bertolucci, V. Basque, A. Mazzacane, C. Montanari, E. Conley, N. Yershov, Marco Adinolfi, M. B. Smy, S. Fuess, M. Kordosky, T. Stokes, J. J. Russell, H. R. Gallagher, D. Pugnere, D. Gratieri, J. R. T. de Mello Neto, L. Li, K. Soustruznik, M. E. Convery, L. Stanco, B. Zamorano, Warner A. Miller, C. A. Moura, A. D. Marino, Wladyslaw Henryk Trzaska, C. Jesús-Valls, Andrew Blake, S. B. Boyd, T. Hill, L. Jiang, Diana Navas-Nicolas, G. A. Valdiviesso, S. Emery, S. Jiménez, E. Cristaldo, H. Razafinime, Stephen P. Gent, Alessandro Montanari, R. Zwaska, S. Green, D. C. Christian, F. Bonini, J. Zuklin, M. Masud, Kristian Harder, J. Hewes, Sandro Palestini, Marc Weber, D. A. Harris, C. Distefano, Ornella Palamara, George Adamov, Andrew Smith, M. Manrique Plata, V. J. Guarino, C. Sarasty, J. Bremer, R. A. Johnson, H. S. Budd, G. Yang, I. Kreslo, M. Parvu, James A. Anderson, V. A. Kudryavtsev, G. S. Davies, I. De Bonis, L. Di Noto, W. E. Sondheim, C. E. Tull, M. Leyton, C. Wilkinson, M. Greenwood, O. Goodwin, K. K. Guthikonda, Simon Jones, S. Di Domizio, G. Meng, A. Lister, A. Christensen, Mariam Tórtola, J. Mills, A. Sousa, Irina Mocioiu, L. Zambelli, A. F. Moor, A. M. Iliescu, Alex Reynolds, K. Biery, Yanchu Wang, Christopher J. Milne, A. Aranda-Fernandez, M. Potekhin, R. S. Fitzpatrick, V. Aushev, L. Rakotondravohitra, J. Zalesak, L. Simard, L. Pagani, Matthew Mewes, J. Rodriguez Rondon, Kai Loo, J. Trevor, Alec Habig, S. Matsuno, D. J. Summers, L. Cremonesi, A. Tonazzo, J. R. Macier, F. Ferraro, J. Freestone, D. Rivera, K. Mavrokoridis, S. Santana, C. Mariani, Carlos Escobar, J. Vasel, J. A. Gonzalez-Cuevas, J. Franc, H. A. Tanaka, B. Kirby, A. Bross, D. Warner, C. E. Thorn, Robert Wilson, Marco Verzocchi, S. J. Patton, E. Church, Sandip Pakvasa, G. S. Varner, A. Hourlier, Paola Sala, D. Shooltz, Zelimir Djurcic, Alessandro Thea, Y. Bezawada, V. P. Luzio, Janice L. Thompson, F. Kamiya, E. Raguzin, L. C. J. Rice, Bo Yu, A. V. Waldron, J. L. Bazo Alba, Y. Cui, P. A. Rodrigues, M. C. Goodman, T. Loew, P. Ding, J. D. Eisch, A. Weinstein, A. Sitraka, L. Bagby, J. M. LoSecco, F. Bento Neves, Andrew Brandt, Ihn Sik Seong, C. M. Sutera, E. Smith, W. Metcalf, T. Wongjirad, A. Delbart, N. J. C. Spooner, E. Pantic, James Stewart, L. W. Koerner, T. Wachala, Barry King, R. Mazza, Keith Rielage, N. Dokania, L. S. Gomez Fajardo, M. P. Decowski, V. Galymov, E. Chardonnet, B. R. Littlejohn, B. Russell, M. Vagins, Jordan Ott, Niki Saoulidou, E. Mazzucato, S. Tariq, Gregory J Pawloski, T. Prakash, Arsen Khvedelidze, A.S. Dyshkant, M. A. Uchida, M. Reggiani-Guzzo, M. Á. García-Peris, M. Kabirnezhad, Pierre Baldi, M. Mooney, E. Tyley, A. Hahn, F. Spagliardi, M. Newcomer, H. W. Sobel, F. D. M. Blaszczyk, Lina Necib, Enrique Fernandez-Martinez, J. S. Real, M. A. Ramirez Delgado, H. Steiner, S. Lockwitz, G. Sinev, Massimo Rossella, S. J. Brice, Nicolas Lurkin, A. A. Machado, Jaroslaw Pasternak, W. Gu, J. Maricic, H. Schellman, Stefan Antusch, Z. Parsa, Patrick Dunne, M. C. Sanchez, A. N. Khotjantsev, N. Tsverava, Marco Pallavicini, G. Savage, J. Soto-Oton, G. Pessina, M. Chalifour, Abi B., Acciarri R., Acero M.A., Adamov G., Adams D., Adinolfi M., Ahmad Z., Ahmed J., Alion T., Monsalve S.A., Alt C., Anderson J., Andreopoulos C., Andrews M., Andrianala F., Andringa S., Ankowski A., Antonova M., Antusch S., Aranda-Fernandez A., Ariga A., Arnold L.O., Arroyave M.A., Asaadi J., Aurisano A., Aushev V., Autiero D., Azfar F., Back H., Back J.J., Backhouse C., Baesso P., Bagby L., Bajou R., Balasubramanian S., Baldi P., Bambah B., Barao F., Barenboim G., Barker G., Barkhouse W., Barnes C., Barr G., Monarca J.B., Barros N., Barrow J.L., Bashyal A., Basque V., Bay F., Alba J.B., Beacom J.F., Bechetoille E., Behera B., Bellantoni L., Bellettini G., Bellini V., Beltramello O., Belver D., Benekos N., Neves F.B., Berger J., Berkman S., Bernardini P., Berner R.M., Berns H., Bertolucci S., Betancourt M., Bezawada Y., Bhattacharjee M., Bhuyan B., Biagi S., Bian J., Biassoni M., Biery K., Bilki B., Bishai M., Bitadze A., Blake A., Siffert B.B., Blaszczyk F., Blazey G., Blucher E., Boissevain J., Bolognesi S., Bolton T., Bonesini M., Bongrand M., Bonini F., Booth A., Booth C., Bordoni S., Borkum A., Boschi T., Bostan N., Bour P., Boyd S., Boyden D., Bracinik J., Braga D., Brailsford D., Brandt A., Bremer J., Brew C., Brianne E., Brice S.J., Brizzolari C., Bromberg C., Brooijmans G., Brooke J., Bross A., Brunetti G., Buchanan N., Budd H., Caiulo D., Calafiura P., Calcutt J., Calin M., Calvez S., Calvo E., Camilleri L., Caminata A., Campanelli M., Caratelli D., Carini G., Carlus B., Carniti P., Terrazas I.C., Carranza H., Castillo A., Castromonte C., Cattadori C., Cavalier F., Cavanna F., Centro S., Cerati G., Cervelli A., Villanueva A.C., Chalifour M., Chang C., Chardonnet E., Chatterjee A., Chattopadhyay S., Chaves J., Chen H., Chen M., Chen Y., Cherdack D., Chi C., Childress S., Chiriacescu A., Cho K., Choubey S., Christensen A., Christian D., Christodoulou G., Church E., Clarke P., Coan T.E., Cocco A.G., Coelho J., Conley E., Conrad J., Convery M., Corwin L., Cotte P., Cremaldi L., Cremonesi L., Crespo-Anadon J.I., Cristaldo E., Cross R., Cuesta C., Cui Y., Cussans D., Dabrowski M., Motta H.D., Peres L.D.S., David Q., Davies G.S., Davini S., Dawson J., De K., Almeida R.M.D., Debbins P., Bonis I.D., Decowski M., Gouvea A.D., Holanda P.C.D., Astiz I.L.D.I., Deisting A., Jong P.D., Delbart A., Delepine D., Delgado M., Dell'acqua A., Lurgio P.D., Neto J.R.D.M., Demuth D.M., Dennis S., Densham C., Deptuch G., Roeck A.D., Romeri V.D., Vries J.D., Dharmapalan R., Dias M., Diaz F., Diaz J., Domizio S.D., Giulio L.D., Ding P., Noto L.D., Distefano C., Diurba R., Diwan M., Djurcic Z., Dokania N., Dolinski M., Domine L., Douglas D., Drielsma F., Duchesneau D., Duffy K., Dunne P., Durkin T., Duyang H., Dvornikov O., Dwyer D., Dyshkant A., Eads M., Edmunds D., Eisch J., Emery S., Ereditato A., Escobar C., Sanchez L.E., Evans J.J., Ewart E., Ezeribe A.C., Fahey K., Falcone A., Farnese C., Farzan Y., Felix J., Fernandez-Martinez E., Menendez P.F., Ferraro F., Fields L., Filkins A., Filthaut F., Fitzpatrick R.S., Flanagan W., Fleming B., Flight R., Fowler J., Fox W., Franc J., Francis K., Franco D., Freeman J., Freestone J., Fried J., Friedland A., Fuess S., Furic I., Furmanski A.P., Gago A., Gallagher H., Gallego-Ros A., Gallice N., Galymov V., Gamberini E., Gamble T., Gandhi R., Gandrajula R., Gao S., Garcia-Gamez D., Garcia-Peris M.A., Gardiner S., Gastler D., Ge G., Gelli B., Gendotti A., Gent S., Ghorbani-Moghaddam Z., Gibin D., Gil-Botella I., Girerd C., Giri A., Gnani D., Gogota O., Gold M., Gollapinni S., Gollwitzer K., Gomes R.A., Bermeo L.G., Fajardo L.S.G., Gonnella F., Gonzalez-Cuevas J., Goodman M.C., Goodwin O., Goswami S., Gotti C., Goudzovski E., Grace C., Graham M., Gramellini E., Gran R., Granados E., Grant A., Grant C., Gratieri D., Green P., Green S., Greenler L., Greenwood M., Greer J., Griffith C., Groh M., Grudzinski J., Grzelak K., Gu W., Guarino V., Guenette R., Guglielmi A., Guo B., Guthikonda K., Gutierrez R., Guzowski P., Guzzo M.M., Gwon S., Habig A., Hackenburg A., Hadavand H., Haenni R., Hahn A., Haigh J., Haiston J., Hamernik T., Hamilton P., Han J., Harder K., Harris D.A., Hartnell J., Hasegawa T., Hatcher R., Hazen E., Heavey A., Heeger K.M., Hennessy K., Henry S., Morquecho M.H., Herner K., Hertel L., Hesam A.S., Hewes J., Pichardo A.H., Hill T., Hillier S.J., Himmel A., Hoff J., Hohl C., Holin A., Hoppe E., Horton-Smith G.A., Hostert M., Hourlier A., Howard B., Howell R., Huang J., Hugon J., Iles G., Iliescu A.M., Illingworth R., Ioannisian A., Itay R., Izmaylov A., James E., Jargowsky B., Jediny F., Jesus-Valls C., Ji X., Jiang L., Jimenez S., Jipa A., Joglekar A., Johnson C., Johnson R., Jones B., Jones S., Jung C., Junk T., Jwa Y., Kabirnezhad M., Kaboth A., Kadenko I., Kamiya F., Karagiorgi G., Karcher A., Karolak M., Karyotakis Y., Kasai S., Kasetti S.P., Kashur L., Kazaryan N., Kearns E., Keener P., Kelly K.J., Kemp E., Ketchum W., Kettell S., Khabibullin M., Khotjantsev A., Khvedelidze A., Kim D., King B., Kirby B., Kirby M., Klein J., Koehler K., Koerner L.W., Kohn S., Koller P.P., Kordosky M., Kosc T., Kose U., Kostelecky V., Kothekar K., Krennrich F., Kreslo I., Kudenko Y., Kudryavtsev V., Kulagin S., Kumar J., Kumar R., Kuruppu C., Kus V., Kutter T., Lambert A., Lande K., Lane C.E., Lang K., Langford T., Lasorak P., Last D., Lastoria C., Laundrie A., Lawrence A., Lazanu I., Lazur R., Le T., Learned J., Lebrun P., Miotto G.L., Lehnert R., De Oliveira M.L., Leitner M., Leyton M., Li L., Li S., Li T., Li Y., Liao H., Lin C., Lin S., Lister A., Littlejohn B.R., Liu J., Lockwitz S., Loew T., Lokajicek M., Lomidze I., Long K., Loo K., Lorca D., Lord T., Losecco J., Louis W.C., Luk K., Luo X., Lurkin N., Lux T., Luzio V.P., MacFarland D., MacHado A., MacHado P., MacIas C., MacIer J., Maddalena A., Madigan P., Magill S., Mahn K., Maio A., Maloney J.A., Mandrioli G., Maneira J.C., Manenti L., Manly S., Mann A., Manolopoulos K., Plata M.M., Marchionni A., Marciano W., Marfatia D., Mariani C., Maricic J., Marinho F., Marino A.D., Marshak M., Marshall C., Marshall J., Marteau J., Martin-Albo J., Martinez N., Caicedo D.A.M., Martynenko S., Mason K., Mastbaum A., Masud M., Matsuno S., Matthews J., Mauger C., Mauri N., Mavrokoridis K., Mazza R., Mazzacane A., Mazzucato E., McCluskey E., McConkey N., McFarland K.S., McGrew C., McNab A., Mefodiev A., Mehta P., Melas P., Mellinato M., Mena O., Menary S., Mendez H., Menegolli A., Meng G., Messier M., Metcalf W., Mewes M., Meyer H., Miao T., Michna G., Miedema T., Migenda J., Milincic R., Miller W., Mills J., Milne C., Mineev O., Miranda O.G., Miryala S., Mishra C., Mishra S., Mislivec A., Mladenov D., Mocioiu I., Moffat K., Moggi N., Mohanta R., Mohayai T.A., Mokhov N., Molina J.A., Bueno L.M., Montanari A., Montanari C., Montanari D., Zetina L.M.M., Moon J., Mooney M., Moor A., Moreno D., Morgan B., Morris C., Mossey C., Motuk E., Moura C.A., Mousseau J., Mu W., Mualem L., Mueller J., Muether M., Mufson S., Muheim F., Muir A., Mulhearn M., Muramatsu H., Murphy S., Musser J., Nachtman J., Nagu S., Nalbandyan M., Nandakumar R., Naples D., Narita S., Navas-Nicolas D., Nayak N., Nebot-Guinot M., Necib L., Negishi K., Nelson J.K., Nesbit J., Nessi M., Newbold D., Newcomer M., Newhart D., Nichol R., Niner E., Nishimura K., Norman A., Northrop R., Novella P., Nowak J.A., Oberling M., Campo A.O.D., Olivier A., Onel Y., Onishchuk Y., Ott J., Pagani L., Pakvasa S., Palamara O., Palestini S., Paley J.M., Pallavicini M., Palomares C., Pantic E., Paolone V., Papadimitriou V., Papaleo R., Papanestis A., Paramesvaran S., Parke S., Parsa Z., Parvu M., Pascoli S., Pasqualini L., Pasternak J., Pater J., Patrick C., Patrizii L., Patterson R.B., Patton S., Patzak T., Paudel A., Paulos B., Paulucci L., Pavlovic Z., Pawloski G., Payne D., Pec V., Peeters S.J., Penichot Y., Pennacchio E., Penzo A., Peres O.L., Perry J., Pershey D., Pessina G., Petrillo G., Petta C., Petti R., Piastra F., Pickering L., Pietropaolo F., Pillow J., Plunkett R., Poling R., Pons X., Poonthottathil N., Pordes S., Potekhin M., Potenza R., Potukuchi B.V., Pozimski J., Pozzato M., Prakash S., Prakash T., Prince S., Prior G., Pugnere D., Qi K., Qian X., Raaf J., Raboanary R., Radeka V., Rademacker J., Radics B., Rafique A., Raguzin E., Rai M., Rajaoalisoa M., Rakhno I., Rakotondramanana H., Rakotondravohitra L., Ramachers Y., Rameika R., Delgado M.R., Ramson B., Rappoldi A., Raselli G., Ratoff P., Ravat S., Razafinime H., Real J., Rebel B., Redondo D., Reggiani-Guzzo M., Rehak T., Reichenbacher J., Reitzner S.D., Renshaw A., Rescia S., Resnati F., Reynolds A., Riccobene G., Rice L.C., Rielage K., Rigaut Y., Rivera D., Rochester L., Roda M., Rodrigues P., Alonso M.R., Rondon J.R., Roeth A., Rogers H., Rosauro-Alcaraz S., Rossella M., Rout J., Roy S., Rubbia A., Rubbia C., Russell B., Russell J., Ruterbories D., Saakyan R., Sacerdoti S., Safford T., Sahu N., Sala P., Samios N., Sanchez M., Sanders D.A., Sankey D., Santana S., Santos-Maldonado M., Saoulidou N., Sapienza P., Sarasty C., Sarcevic I., Savage G., Savinov V., Scaramelli A., Scarff A., Scarpelli A., Schaffer T., Schellman H., Schlabach P., Schmitz D., Scholberg K., Schukraft A., Segreto E., Sensenig J., Seong I., Sergi A., Sergiampietri F., Sgalaberna D., Shaevitz M., Shafaq S., Shamma M., Sharma H.R., Sharma R., Shaw T., Shepherd-Themistocleous C., Shin S., Shooltz D., Shrock R., Simard L., Simos N., Sinclair J., Sinev G., Singh J., Singh V., Sipos R., Sippach F., Sirri G., Sitraka A., Siyeon K., Smargianaki D., Smith A., Smith E., Smith P., Smolik J., Smy M., Snopok P., Nunes M.S., Sobel H., Soderberg M., Salinas C.J.S., Soldner-Rembold S., Solomey N., Solovov V., Sondheim W.E., Sorel M., Soto-Oton J., Sousa A., Soustruznik K., Spagliardi F., Spanu M., Spitz J., Spooner N.J., Spurgeon K., Staley R., Stancari M., Stanco L., Steiner H., Stewart J., Stillwell B., Stock J., Stocker F., Stokes T., Strait M., Strauss T., Striganov S., Stuart A., Summers D., Surdo A., Susic V., Suter L., Sutera C., Svoboda R., Szczerbinska B., Szelc A., Talaga R., Tanaka H., Oregui B.T., Tapper A., Tariq S., Tatar E., Tayloe R., Teklu A., Tenti M., Terao K., Ternes C.A., Terranova F., Testera G., Thea A., Thompson J.L., Thorn C., Timm S., Tonazzo A., Torti M., Tortola M., Tortorici F., Totani D., Toups M., Touramanis C., Trevor J., Trzaska W.H., Tsai Y.T., Tsamalaidze Z., Tsang K., Tsverava N., Tufanli S., Tull C., Tyley E., Tzanov M., Uchida M.A., Urheim J., Usher T., Vagins M., Vahle P., Valdiviesso G., Valencia E., Vallari Z., Valle J.W., Vallecorsa S., Berg R.V., De Water R.G.V., Forero D.V., Varanini F., Vargas D., Varner G., Vasel J., Vasseur G., Vaziri K., Ventura S., Verdugo A., Vergani S., Vermeulen M.A., Verzocchi M., De Souza H.V., Vignoli C., Vilela C., Viren B., Vrba T., Wachala T., Waldron A.V., Wallbank M., Wang H., Wang J., Wang Y., Warburton K., Warner D., Wascko M., Waters D., Watson A., Weatherly P., Weber A., Weber M., Wei H., Weinstein A., Wenman D., Wetstein M., While M.R., White A., Whitehead L.H., Whittington D., Wilking M.J., Wilkinson C., Williams Z., Wilson F., Wilson R.J., Wolcott J., Wongjirad T., Wood K., Wood L., Worcester E., Worcester M., Wret C., Wu W., Xiao Y., Yang G., Yang T., Yershov N., Yonehara K., Young T., Yu B., Yu J., Zalesak J., Zambelli L., Zamorano B., Zani A., Zazueta L., Zeller G., Zennamo J., Zeug K., Zhang C., Zhao M., Zhivun E., Zhu G., Zimmerman E.D., Zito M., Zucchelli S., Zuklin J., Zutshi V., Zwaska R., Abi, B, Acciarri, R, Acero, M, Adamov, G, Adams, D, Adinolfi, M, Ahmad, Z, Ahmed, J, Alion, T, Monsalve, S, Alt, C, Anderson, J, Andreopoulos, C, Andrews, M, Andrianala, F, Andringa, S, Ankowski, A, Antonova, M, Antusch, S, Aranda-Fernandez, A, Ariga, A, Arnold, L, Arroyave, M, Asaadi, J, Aurisano, A, Aushev, V, Autiero, D, Azfar, F, Back, H, Back, J, Backhouse, C, Baesso, P, Bagby, L, Bajou, R, Balasubramanian, S, Baldi, P, Bambah, B, Barao, F, Barenboim, G, Barker, G, Barkhouse, W, Barnes, C, Barr, G, Monarca, J, Barros, N, Barrow, J, Bashyal, A, Basque, V, Bay, F, Alba, J, Beacom, J, Bechetoille, E, Behera, B, Bellantoni, L, Bellettini, G, Bellini, V, Beltramello, O, Belver, D, Benekos, N, Neves, F, Berger, J, Berkman, S, Bernardini, P, Berner, R, Berns, H, Bertolucci, S, Betancourt, M, Bezawada, Y, Bhattacharjee, M, Bhuyan, B, Biagi, S, Bian, J, Biassoni, M, Biery, K, Bilki, B, Bishai, M, Bitadze, A, Blake, A, Siffert, B, Blaszczyk, F, Blazey, G, Blucher, E, Boissevain, J, Bolognesi, S, Bolton, T, Bonesini, M, Bongrand, M, Bonini, F, Booth, A, Booth, C, Bordoni, S, Borkum, A, Boschi, T, Bostan, N, Bour, P, Boyd, S, Boyden, D, Bracinik, J, Braga, D, Brailsford, D, Brandt, A, Bremer, J, Brew, C, Brianne, E, Brice, S, Brizzolari, C, Bromberg, C, Brooijmans, G, Brooke, J, Bross, A, Brunetti, G, Buchanan, N, Budd, H, Caiulo, D, Calafiura, P, Calcutt, J, Calin, M, Calvez, S, Calvo, E, Camilleri, L, Caminata, A, Campanelli, M, Caratelli, D, Carini, G, Carlus, B, Carniti, P, Terrazas, I, Carranza, H, Castillo, A, Castromonte, C, Cattadori, C, Cavalier, F, Cavanna, F, Centro, S, Cerati, G, Cervelli, A, Villanueva, A, Chalifour, M, Chang, C, Chardonnet, E, Chatterjee, A, Chattopadhyay, S, Chaves, J, Chen, H, Chen, M, Chen, Y, Cherdack, D, Chi, C, Childress, S, Chiriacescu, A, Cho, K, Choubey, S, Christensen, A, Christian, D, Christodoulou, G, Church, E, Clarke, P, Coan, T, Cocco, A, Coelho, J, Conley, E, Conrad, J, Convery, M, Corwin, L, Cotte, P, Cremaldi, L, Cremonesi, L, Crespo-Anadon, J, Cristaldo, E, Cross, R, Cuesta, C, Cui, Y, Cussans, D, Dabrowski, M, Motta, H, Peres, L, David, Q, Davies, G, Davini, S, Dawson, J, De, K, Almeida, R, Debbins, P, Bonis, I, Decowski, M, Gouvea, A, Holanda, P, Astiz, I, Deisting, A, Jong, P, Delbart, A, Delepine, D, Delgado, M, Dell'Acqua, A, Lurgio, P, Neto, J, Demuth, D, Dennis, S, Densham, C, Deptuch, G, Roeck, A, Romeri, V, Vries, J, Dharmapalan, R, Dias, M, Diaz, F, Diaz, J, Domizio, S, Giulio, L, Ding, P, Noto, L, Distefano, C, Diurba, R, Diwan, M, Djurcic, Z, Dokania, N, Dolinski, M, Domine, L, Douglas, D, Drielsma, F, Duchesneau, D, Duffy, K, Dunne, P, Durkin, T, Duyang, H, Dvornikov, O, Dwyer, D, Dyshkant, A, Eads, M, Edmunds, D, Eisch, J, Emery, S, Ereditato, A, Escobar, C, Sanchez, L, Evans, J, Ewart, E, Ezeribe, A, Fahey, K, Falcone, A, Farnese, C, Farzan, Y, Felix, J, Fernandez-Martinez, E, Menendez, P, Ferraro, F, Fields, L, Filkins, A, Filthaut, F, Fitzpatrick, R, Flanagan, W, Fleming, B, Flight, R, Fowler, J, Fox, W, Franc, J, Francis, K, Franco, D, Freeman, J, Freestone, J, Fried, J, Friedland, A, Fuess, S, Furic, I, Furmanski, A, Gago, A, Gallagher, H, Gallego-Ros, A, Gallice, N, Galymov, V, Gamberini, E, Gamble, T, Gandhi, R, Gandrajula, R, Gao, S, Garcia-Gamez, D, Garcia-Peris, M, Gardiner, S, Gastler, D, Ge, G, Gelli, B, Gendotti, A, Gent, S, Ghorbani-Moghaddam, Z, Gibin, D, Gil-Botella, I, Girerd, C, Giri, A, Gnani, D, Gogota, O, Gold, M, Gollapinni, S, Gollwitzer, K, Gomes, R, Bermeo, L, Fajardo, L, Gonnella, F, Gonzalez-Cuevas, J, Goodman, M, Goodwin, O, Goswami, S, Gotti, C, Goudzovski, E, Grace, C, Graham, M, Gramellini, E, Gran, R, Granados, E, Grant, A, Grant, C, Gratieri, D, Green, P, Green, S, Greenler, L, Greenwood, M, Greer, J, Griffith, C, Groh, M, Grudzinski, J, Grzelak, K, Gu, W, Guarino, V, Guenette, R, Guglielmi, A, Guo, B, Guthikonda, K, Gutierrez, R, Guzowski, P, Guzzo, M, Gwon, S, Habig, A, Hackenburg, A, Hadavand, H, Haenni, R, Hahn, A, Haigh, J, Haiston, J, Hamernik, T, Hamilton, P, Han, J, Harder, K, Harris, D, Hartnell, J, Hasegawa, T, Hatcher, R, Hazen, E, Heavey, A, Heeger, K, Hennessy, K, Henry, S, Morquecho, M, Herner, K, Hertel, L, Hesam, A, Hewes, J, Pichardo, A, Hill, T, Hillier, S, Himmel, A, Hoff, J, Hohl, C, Holin, A, Hoppe, E, Horton-Smith, G, Hostert, M, Hourlier, A, Howard, B, Howell, R, Huang, J, Hugon, J, Iles, G, Iliescu, A, Illingworth, R, Ioannisian, A, Itay, R, Izmaylov, A, James, E, Jargowsky, B, Jediny, F, Jesus-Valls, C, Ji, X, Jiang, L, Jimenez, S, Jipa, A, Joglekar, A, Johnson, C, Johnson, R, Jones, B, Jones, S, Jung, C, Junk, T, Jwa, Y, Kabirnezhad, M, Kaboth, A, Kadenko, I, Kamiya, F, Karagiorgi, G, Karcher, A, Karolak, M, Karyotakis, Y, Kasai, S, Kasetti, S, Kashur, L, Kazaryan, N, Kearns, E, Keener, P, Kelly, K, Kemp, E, Ketchum, W, Kettell, S, Khabibullin, M, Khotjantsev, A, Khvedelidze, A, Kim, D, King, B, Kirby, B, Kirby, M, Klein, J, Koehler, K, Koerner, L, Kohn, S, Koller, P, Kordosky, M, Kosc, T, Kose, U, Kostelecky, V, Kothekar, K, Krennrich, F, Kreslo, I, Kudenko, Y, Kudryavtsev, V, Kulagin, S, Kumar, J, Kumar, R, Kuruppu, C, Kus, V, Kutter, T, Lambert, A, Lande, K, Lane, C, Lang, K, Langford, T, Lasorak, P, Last, D, Lastoria, C, Laundrie, A, Lawrence, A, Lazanu, I, Lazur, R, Le, T, Learned, J, Lebrun, P, Miotto, G, Lehnert, R, De Oliveira, M, Leitner, M, Leyton, M, Li, L, Li, S, Li, T, Li, Y, Liao, H, Lin, C, Lin, S, Lister, A, Littlejohn, B, Liu, J, Lockwitz, S, Loew, T, Lokajicek, M, Lomidze, I, Long, K, Loo, K, Lorca, D, Lord, T, Losecco, J, Louis, W, Luk, K, Luo, X, Lurkin, N, Lux, T, Luzio, V, Macfarland, D, Machado, A, Machado, P, Macias, C, Macier, J, Maddalena, A, Madigan, P, Magill, S, Mahn, K, Maio, A, Maloney, J, Mandrioli, G, Maneira, J, Manenti, L, Manly, S, Mann, A, Manolopoulos, K, Plata, M, Marchionni, A, Marciano, W, Marfatia, D, Mariani, C, Maricic, J, Marinho, F, Marino, A, Marshak, M, Marshall, C, Marshall, J, Marteau, J, Martin-Albo, J, Martinez, N, Caicedo, D, Martynenko, S, Mason, K, Mastbaum, A, Masud, M, Matsuno, S, Matthews, J, Mauger, C, Mauri, N, Mavrokoridis, K, Mazza, R, Mazzacane, A, Mazzucato, E, Mccluskey, E, Mcconkey, N, Mcfarland, K, Mcgrew, C, Mcnab, A, Mefodiev, A, Mehta, P, Melas, P, Mellinato, M, Mena, O, Menary, S, Mendez, H, Menegolli, A, Meng, G, Messier, M, Metcalf, W, Mewes, M, Meyer, H, Miao, T, Michna, G, Miedema, T, Migenda, J, Milincic, R, Miller, W, Mills, J, Milne, C, Mineev, O, Miranda, O, Miryala, S, Mishra, C, Mishra, S, Mislivec, A, Mladenov, D, Mocioiu, I, Moffat, K, Moggi, N, Mohanta, R, Mohayai, T, Mokhov, N, Molina, J, Bueno, L, Montanari, A, Montanari, C, Montanari, D, Zetina, L, Moon, J, Mooney, M, Moor, A, Moreno, D, Morgan, B, Morris, C, Mossey, C, Motuk, E, Moura, C, Mousseau, J, Mu, W, Mualem, L, Mueller, J, Muether, M, Mufson, S, Muheim, F, Muir, A, Mulhearn, M, Muramatsu, H, Murphy, S, Musser, J, Nachtman, J, Nagu, S, Nalbandyan, M, Nandakumar, R, Naples, D, Narita, S, Navas-Nicolas, D, Nayak, N, Nebot-Guinot, M, Necib, L, Negishi, K, Nelson, J, Nesbit, J, Nessi, M, Newbold, D, Newcomer, M, Newhart, D, Nichol, R, Niner, E, Nishimura, K, Norman, A, Northrop, R, Novella, P, Nowak, J, Oberling, M, Campo, A, Olivier, A, Onel, Y, Onishchuk, Y, Ott, J, Pagani, L, Pakvasa, S, Palamara, O, Palestini, S, Paley, J, Pallavicini, M, Palomares, C, Pantic, E, Paolone, V, Papadimitriou, V, Papaleo, R, Papanestis, A, Paramesvaran, S, Parke, S, Parsa, Z, Parvu, M, Pascoli, S, Pasqualini, L, Pasternak, J, Pater, J, Patrick, C, Patrizii, L, Patterson, R, Patton, S, Patzak, T, Paudel, A, Paulos, B, Paulucci, L, Pavlovic, Z, Pawloski, G, Payne, D, Pec, V, Peeters, S, Penichot, Y, Pennacchio, E, Penzo, A, Peres, O, Perry, J, Pershey, D, Pessina, G, Petrillo, G, Petta, C, Petti, R, Piastra, F, Pickering, L, Pietropaolo, F, Pillow, J, Plunkett, R, Poling, R, Pons, X, Poonthottathil, N, Pordes, S, Potekhin, M, Potenza, R, Potukuchi, B, Pozimski, J, Pozzato, M, Prakash, S, Prakash, T, Prince, S, Prior, G, Pugnere, D, Qi, K, Qian, X, Raaf, J, Raboanary, R, Radeka, V, Rademacker, J, Radics, B, Rafique, A, Raguzin, E, Rai, M, Rajaoalisoa, M, Rakhno, I, Rakotondramanana, H, Rakotondravohitra, L, Ramachers, Y, Rameika, R, Ramson, B, Rappoldi, A, Raselli, G, Ratoff, P, Ravat, S, Razafinime, H, Real, J, Rebel, B, Redondo, D, Reggiani-Guzzo, M, Rehak, T, Reichenbacher, J, Reitzner, S, Renshaw, A, Rescia, S, Resnati, F, Reynolds, A, Riccobene, G, Rice, L, Rielage, K, Rigaut, Y, Rivera, D, Rochester, L, Roda, M, Rodrigues, P, Alonso, M, Rondon, J, Roeth, A, Rogers, H, Rosauro-Alcaraz, S, Rossella, M, Rout, J, Roy, S, Rubbia, A, Rubbia, C, Russell, B, Russell, J, Ruterbories, D, Saakyan, R, Sacerdoti, S, Safford, T, Sahu, N, Sala, P, Samios, N, Sanchez, M, Sanders, D, Sankey, D, Santana, S, Santos-Maldonado, M, Saoulidou, N, Sapienza, P, Sarasty, C, Sarcevic, I, Savage, G, Savinov, V, Scaramelli, A, Scarff, A, Scarpelli, A, Schaffer, T, Schellman, H, Schlabach, P, Schmitz, D, Scholberg, K, Schukraft, A, Segreto, E, Sensenig, J, Seong, I, Sergi, A, Sergiampietri, F, Sgalaberna, D, Shaevitz, M, Shafaq, S, Shamma, M, Sharma, H, Sharma, R, Shaw, T, Shepherd-Themistocleous, C, Shin, S, Shooltz, D, Shrock, R, Simard, L, Simos, N, Sinclair, J, Sinev, G, Singh, J, Singh, V, Sipos, R, Sippach, F, Sirri, G, Sitraka, A, Siyeon, K, Smargianaki, D, Smith, A, Smith, E, Smith, P, Smolik, J, Smy, M, Snopok, P, Nunes, M, Sobel, H, Soderberg, M, Salinas, C, Soldner-Rembold, S, Solomey, N, Solovov, V, Sondheim, W, Sorel, M, Soto-Oton, J, Sousa, A, Soustruznik, K, Spagliardi, F, Spanu, M, Spitz, J, Spooner, N, Spurgeon, K, Staley, R, Stancari, M, Stanco, L, Steiner, H, Stewart, J, Stillwell, B, Stock, J, Stocker, F, Stokes, T, Strait, M, Strauss, T, Striganov, S, Stuart, A, Summers, D, Surdo, A, Susic, V, Suter, L, Sutera, C, Svoboda, R, Szczerbinska, B, Szelc, A, Talaga, R, Tanaka, H, Oregui, B, Tapper, A, Tariq, S, Tatar, E, Tayloe, R, Teklu, A, Tenti, M, Terao, K, Ternes, C, Terranova, F, Testera, G, Thea, A, Thompson, J, Thorn, C, Timm, S, Tonazzo, A, Torti, M, Tortola, M, Tortorici, F, Totani, D, Toups, M, Touramanis, C, Trevor, J, Trzaska, W, Tsai, Y, Tsamalaidze, Z, Tsang, K, Tsverava, N, Tufanli, S, Tull, C, Tyley, E, Tzanov, M, Uchida, M, Urheim, J, Usher, T, Vagins, M, Vahle, P, Valdiviesso, G, Valencia, E, Vallari, Z, Valle, J, Vallecorsa, S, Berg, R, De Water, R, Forero, D, Varanini, F, Vargas, D, Varner, G, Vasel, J, Vasseur, G, Vaziri, K, Ventura, S, Verdugo, A, Vergani, S, Vermeulen, M, Verzocchi, M, De Souza, H, Vignoli, C, Vilela, C, Viren, B, Vrba, T, Wachala, T, Waldron, A, Wallbank, M, Wang, H, Wang, J, Wang, Y, Warburton, K, Warner, D, Wascko, M, Waters, D, Watson, A, Weatherly, P, Weber, A, Weber, M, Wei, H, Weinstein, A, Wenman, D, Wetstein, M, While, M, White, A, Whitehead, L, Whittington, D, Wilking, M, Wilkinson, C, Williams, Z, Wilson, F, Wilson, R, Wolcott, J, Wongjirad, T, Wood, K, Wood, L, Worcester, E, Worcester, M, Wret, C, Wu, W, Xiao, Y, Yang, G, Yang, T, Yershov, N, Yonehara, K, Young, T, Yu, B, Yu, J, Zalesak, J, Zambelli, L, Zamorano, B, Zani, A, Zazueta, L, Zeller, G, Zennamo, J, Zeug, K, Zhang, C, Zhao, M, Zhivun, E, Zhu, G, Zimmerman, E, Zito, M, Zucchelli, S, Zuklin, J, Zutshi, V, Zwaska, R, Abi, B., Acciarri, R., Acero, M. A., Adamov, G., Adams, D., Adinolfi, M., Ahmad, Z., Ahmed, J., Alion, T., Monsalve, S. Alonso, Alt, C., Anderson, J., Andreopoulos, C., Andrews, M., Andrianala, F., Andringa, S., Ankowski, A., Antonova, M., Antusch, S., Aranda-Fernandez, A., Ariga, A., Arnold, L. O., Arroyave, M. A., Asaadi, J., Aurisano, A., Aushev, V., Autiero, D., Azfar, F., Back, H., Back, J. J., Backhouse, C., Baesso, P., Bagby, L., Bajou, R., Balasubramanian, S., Baldi, P., Bambah, B., Barao, F., Barenboim, G., Barker, G., Barkhouse, W., Barnes, C., Barr, G., Monarca, J. Barranco, Barros, N., Barrow, J. L., Bashyal, A., Basque, V., Bay, F., Alba, J. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Belver, D., Benekos, N., Neves, F. Bento, Berger, J., Berkman, S., Bernardini, P., Berner, R. M., Berns, H., Bertolucci, S., Betancourt, M., Bezawada, Y., Bhattacharjee, M., Bhuyan, B., Biagi, S., Bian, J., Biassoni, M., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Siffert, B. Blanco, Blaszczyk, F., Blazey, G., Blucher, E., Boissevain, J., Bolognesi, S., Bolton, T., Bonesini, M., Bongrand, M., Bonini, F., Booth, A., Booth, C., Bordoni, S., Borkum, A., Boschi, T., Bostan, N., Bour, P., Boyd, S., Boyden, D., Bracinik, J., Braga, D., Brailsford, D., Brandt, A., Bremer, J., Brew, C., Brianne, E., Brice, S. J., Brizzolari, C., Bromberg, C., Brooijmans, G., Brooke, J., Bross, A., Brunetti, G., Buchanan, N., Budd, H., Caiulo, D., Calafiura, P., Calcutt, J., Calin, M., Calvez, S., Calvo, E., Camilleri, L., Caminata, A., Campanelli, M., Caratelli, D., Carini, G., Carlus, B., Carniti, P., Terrazas, I. Caro, Carranza, H., Castillo, A., Castromonte, C., Cattadori, C., Cavalier, F., Cavanna, F., Centro, S., Cerati, G., Cervelli, A., Villanueva, A. Cervera, Chalifour, M., Chang, C., Chardonnet, E., Chatterjee, A., Chattopadhyay, S., Chaves, J., Chen, H., Chen, M., Chen, Y., Cherdack, D., Chi, C., Childress, S., Chiriacescu, A., Cho, K., Choubey, S., Christensen, A., Christian, D., Christodoulou, G., Church, E., Clarke, P., Coan, T. E., Cocco, A. G., Coelho, J., Conley, E., Conrad, J., Convery, M., Corwin, L., Cotte, P., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Cristaldo, E., Cross, R., Cuesta, C., Cui, Y., Cussans, D., Dabrowski, M., Motta, H. Da, Peres, L. Da Silva, David, Q., Davies, G. S., Davini, S., Dawson, J., De, K., Almeida, R. M. De, Debbins, P., Bonis, I. De, Decowski, M., Gouvea, A. De, Holanda, P. C. De, Astiz, I. L. De Icaza, Deisting, A., Jong, P. De, Delbart, A., Delepine, D., Delgado, M., Dell'Acqua, A., Lurgio, P. De, Neto, J. R. De Mello, Demuth, D. M., Dennis, S., Densham, C., Deptuch, G., Roeck, A. De, Romeri, V. De, Vries, J. De, Dharmapalan, R., Dias, M., Diaz, F., Diaz, J., Domizio, S. Di, Giulio, L. Di, Ding, P., Noto, L. Di, Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Dokania, N., Dolinski, M., Domine, L., Douglas, D., Drielsma, F., Duchesneau, D., Duffy, K., Dunne, P., Durkin, T., Duyang, H., Dvornikov, O., Dwyer, D., Dyshkant, A., Eads, M., Edmunds, D., Eisch, J., Emery, S., Ereditato, A., Escobar, C., Sanchez, L. Escudero, Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Falcone, A., Farnese, C., Farzan, Y., Felix, J., Fernandez-Martinez, E., Menendez, P. Fernandez, Ferraro, F., Fields, L., Filkins, A., Filthaut, F., Fitzpatrick, R. S., Flanagan, W., Fleming, B., Flight, R., Fowler, J., Fox, W., Franc, J., Francis, K., Franco, D., Freeman, J., Freestone, J., Fried, J., Friedland, A., Fuess, S., Furic, I., Furmanski, A. P., Gago, A., Gallagher, H., Gallego-Ros, A., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Gandhi, R., Gandrajula, R., Gao, S., Garcia-Gamez, D., García-Peris, M. Á., Gardiner, S., Gastler, D., Ge, G., Gelli, B., Gendotti, A., Gent, S., Ghorbani-Moghaddam, Z., Gibin, D., Gil-Botella, I., Girerd, C., Giri, A., Gnani, D., Gogota, O., Gold, M., Gollapinni, S., Gollwitzer, K., Gomes, R. A., Bermeo, L. Gomez, Fajardo, L. S. Gomez, Gonnella, F., Gonzalez-Cuevas, J., Goodman, M. C., Goodwin, O., Goswami, S., Gotti, C., Goudzovski, E., Grace, C., Graham, M., Gramellini, E., Gran, R., Granados, E., Grant, A., Grant, C., Gratieri, D., Green, P., Green, S., Greenler, L., Greenwood, M., Greer, J., Griffith, C., Groh, M., Grudzinski, J., Grzelak, K., Gu, W., Guarino, V., Guenette, R., Guglielmi, A., Guo, B., Guthikonda, K., Gutierrez, R., Guzowski, P., Guzzo, M. M., Gwon, S., Habig, A., Hackenburg, A., Hadavand, H., Haenni, R., Hahn, A., Haigh, J., Haiston, J., Hamernik, T., Hamilton, P., Han, J., Harder, K., Harris, D. A., Hartnell, J., Hasegawa, T., Hatcher, R., Hazen, E., Heavey, A., Heeger, K. M., Hennessy, K., Henry, S., Morquecho, M. Hernandez, Herner, K., Hertel, L., Hesam, A. S., Hewes, J., Pichardo, A. Higuera, Hill, T., Hillier, S. J., Himmel, A., Hoff, J., Hohl, C., Holin, A., Hoppe, E., Horton-Smith, G. A., Hostert, M., Hourlier, A., Howard, B., Howell, R., Huang, J., Hugon, J., Iles, G., Iliescu, A. M., Illingworth, R., Ioannisian, A., Itay, R., Izmaylov, A., James, E., Jargowsky, B., Jediny, F., Jesús-Valls, C., Ji, X., Jiang, L., Jiménez, S., Jipa, A., Joglekar, A., Johnson, C., Johnson, R., Jones, B., Jones, S., Jung, C., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A., Kadenko, I., Kamiya, F., Karagiorgi, G., Karcher, A., Karolak, M., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Kazaryan, N., Kearns, E., Keener, P., Kelly, K. J., Kemp, E., Ketchum, W., Kettell, S., Khabibullin, M., Khotjantsev, A., Khvedelidze, A., Kim, D., King, B., Kirby, B., Kirby, M., Klein, J., Koehler, K., Koerner, L. W., Kohn, S., Koller, P. P., Kordosky, M., Kosc, T., Kose, U., Kostelecky, V., Kothekar, K., Krennrich, F., Kreslo, I., Kudenko, Y., Kudryavtsev, V., Kulagin, S., Kumar, J., Kumar, R., Kuruppu, C., Kus, V., Kutter, T., Lambert, A., Lande, K., Lane, C. E., Lang, K., Langford, T., Lasorak, P., Last, D., Lastoria, C., Laundrie, A., Lawrence, A., Lazanu, I., Lazur, R., Le, T., Learned, J., Lebrun, P., Miotto, G. Lehmann, Lehnert, R., de Oliveira, M. Leigui, Leitner, M., Leyton, M., Li, L., Li, S., Li, T., Li, Y., Liao, H., Lin, C., Lin, S., Lister, A., Littlejohn, B. R., Liu, J., Lockwitz, S., Loew, T., Lokajicek, M., Lomidze, I., Long, K., Loo, K., Lorca, D., Lord, T., Losecco, J., Louis, W. C., Luk, K., Luo, X., Lurkin, N., Lux, T., Luzio, V. P., Macfarland, D., Machado, A., Machado, P., Macias, C., Macier, J., Maddalena, A., Madigan, P., Magill, S., Mahn, K., Maio, A., Maloney, J. A., Mandrioli, G., Maneira, J. C., Manenti, L., Manly, S., Mann, A., Manolopoulos, K., Plata, M. Manrique, Marchionni, A., Marciano, W., Marfatia, D., Mariani, C., Maricic, J., Marinho, F., Marino, A. D., Marshak, M., Marshall, C., Marshall, J., Marteau, J., Martin-Albo, J., Martinez, N., Caicedo, D. A. Martinez, Martynenko, S., Mason, K., Mastbaum, A., Masud, M., Matsuno, S., Matthews, J., Mauger, C., Mauri, N., Mavrokoridis, K., Mazza, R., Mazzacane, A., Mazzucato, E., Mccluskey, E., Mcconkey, N., Mcfarland, K. S., Mcgrew, C., Mcnab, A., Mefodiev, A., Mehta, P., Melas, P., Mellinato, M., Mena, O., Menary, S., Mendez, H., Menegolli, A., Meng, G., Messier, M., Metcalf, W., Mewes, M., Meyer, H., Miao, T., Michna, G., Miedema, T., Migenda, J., Milincic, R., Miller, W., Mills, J., Milne, C., Mineev, O., Miranda, O. G., Miryala, S., Mishra, C., Mishra, S., Mislivec, A., Mladenov, D., Mocioiu, I., Moffat, K., Moggi, N., Mohanta, R., Mohayai, T. A., Mokhov, N., Molina, J. A., Bueno, L. Molina, Montanari, A., Montanari, C., Montanari, D., Zetina, L. M. Montano, Moon, J., Mooney, M., Moor, A., Moreno, D., Morgan, B., Morris, C., Mossey, C., Motuk, E., Moura, C. A., Mousseau, J., Mu, W., Mualem, L., Mueller, J., Muether, M., Mufson, S., Muheim, F., Muir, A., Mulhearn, M., Muramatsu, H., Murphy, S., Musser, J., Nachtman, J., Nagu, S., Nalbandyan, M., Nandakumar, R., Naples, D., Narita, S., Navas-Nicolás, D., Nayak, N., Nebot-Guinot, M., Necib, L., Negishi, K., Nelson, J. K., Nesbit, J., Nessi, M., Newbold, D., Newcomer, M., Newhart, D., Nichol, R., Niner, E., Nishimura, K., Norman, A., Northrop, R., Novella, P., Nowak, J. A., Oberling, M., Campo, A. Olivares Del, Olivier, A., Onel, Y., Onishchuk, Y., Ott, J., Pagani, L., Pakvasa, S., Palamara, O., Palestini, S., Paley, J. M., Pallavicini, M., Palomares, C., Pantic, E., Paolone, V., Papadimitriou, V., Papaleo, R., Papanestis, A., Paramesvaran, S., Parke, S., Parsa, Z., Parvu, M., Pascoli, S., Pasqualini, L., Pasternak, J., Pater, J., Patrick, C., Patrizii, L., Patterson, R. B., Patton, S., Patzak, T., Paudel, A., Paulos, B., Paulucci, L., Pavlovic, Z., Pawloski, G., Payne, D., Pec, V., Peeters, S. J., Penichot, Y., Pennacchio, E., Penzo, A., Peres, O. L., Perry, J., Pershey, D., Pessina, G., Petrillo, G., Petta, C., Petti, R., Piastra, F., Pickering, L., Pietropaolo, F., Pillow, J., Plunkett, R., Poling, R., Pons, X., Poonthottathil, N., Pordes, S., Potekhin, M., Potenza, R., Potukuchi, B. V., Pozimski, J., Pozzato, M., Prakash, S., Prakash, T., Prince, S., Prior, G., Pugnere, D., Qi, K., Qian, X., Raaf, J., Raboanary, R., Radeka, V., Rademacker, J., Radics, B., Rafique, A., Raguzin, E., Rai, M., Rajaoalisoa, M., Rakhno, I., Rakotondramanana, H., Rakotondravohitra, L., Ramachers, Y., Rameika, R., Delgado, M. Ramirez, Ramson, B., Rappoldi, A., Raselli, G., Ratoff, P., Ravat, S., Razafinime, H., Real, J., Rebel, B., Redondo, D., Reggiani-Guzzo, M., Rehak, T., Reichenbacher, J., Reitzner, S. D., Renshaw, A., Rescia, S., Resnati, F., Reynolds, A., Riccobene, G., Rice, L. C., Rielage, K., Rigaut, Y., Rivera, D., Rochester, L., Roda, M., Rodrigues, P., Alonso, M. Rodriguez, Rondon, J. Rodriguez, Roeth, A., Rogers, H., Rosauro-Alcaraz, S., Rossella, M., Rout, J., Roy, S., Rubbia, A., Rubbia, C., Russell, B., Russell, J., Ruterbories, D., Saakyan, R., Sacerdoti, S., Safford, T., Sahu, N., Sala, P., Samios, N., Sanchez, M., Sanders, D. A., Sankey, D., Santana, S., Santos-Maldonado, M., Saoulidou, N., Sapienza, P., Sarasty, C., Sarcevic, I., Savage, G., Savinov, V., Scaramelli, A., Scarff, A., Scarpelli, A., Schaffer, T., Schellman, H., Schlabach, P., Schmitz, D., Scholberg, K., Schukraft, A., Segreto, E., Sensenig, J., Seong, I., Sergi, A., Sergiampietri, F., Sgalaberna, D., Shaevitz, M., Shafaq, S., Shamma, M., Sharma, H. R., Sharma, R., Shaw, T., Shepherd-Themistocleous, C., Shin, S., Shooltz, D., Shrock, R., Simard, L., Simos, N., Sinclair, J., Sinev, G., Singh, J., Singh, V., Sipos, R., Sippach, F., Sirri, G., Sitraka, A., Siyeon, K., Smargianaki, D., Smith, A., Smith, E., Smith, P., Smolik, J., Smy, M., Snopok, P., Nunes, M. Soare, Sobel, H., Soderberg, M., Salinas, C. J. Solano, Söldner-Rembold, S., Solomey, N., Solovov, V., Sondheim, W. E., Sorel, M., Soto-Oton, J., Sousa, A., Soustruznik, K., Spagliardi, F., Spanu, M., Spitz, J., Spooner, N. J., Spurgeon, K., Staley, R., Stancari, M., Stanco, L., Steiner, H., Stewart, J., Stillwell, B., Stock, J., Stocker, F., Stokes, T., Strait, M., Strauss, T., Striganov, S., Stuart, A., Summers, D., Surdo, A., Susic, V., Suter, L., Sutera, C., Svoboda, R., Szczerbinska, B., Szelc, A., Talaga, R., Tanaka, H., Oregui, B. Tapia, Tapper, A., Tariq, S., Tatar, E., Tayloe, R., Teklu, A., Tenti, M., Terao, K., Ternes, C. A., Terranova, F., Testera, G., Thea, A., Thompson, J. L., Thorn, C., Timm, S., Tonazzo, A., Torti, M., Tortola, M., Tortorici, F., Totani, D., Toups, M., Touramanis, C., Trevor, J., Trzaska, W. H., Tsai, Y. T., Tsamalaidze, Z., Tsang, K., Tsverava, N., Tufanli, S., Tull, C., Tyley, E., Tzanov, M., Uchida, M. A., Urheim, J., Usher, T., Vagins, M., Vahle, P., Valdiviesso, G., Valencia, E., Vallari, Z., Valle, J. W., Vallecorsa, S., Berg, R. Van, de Water, R. G. Van, Forero, D. Vanega, Varanini, F., Vargas, D., Varner, G., Vasel, J., Vasseur, G., Vaziri, K., Ventura, S., Verdugo, A., Vergani, S., Vermeulen, M. A., Verzocchi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Viren, B., Vrba, T., Wachala, T., Waldron, A. V., Wallbank, M., Wang, H., Wang, J., Wang, Y., Warburton, K., Warner, D., Wascko, M., Waters, D., Watson, A., Weatherly, P., Weber, A., Weber, M., Wei, H., Weinstein, A., Wenman, D., Wetstein, M., While, M. R., White, A., Whitehead, L. H., Whittington, D., Wilking, M. J., Wilkinson, C., Williams, Z., Wilson, F., Wilson, R. J., Wolcott, J., Wongjirad, T., Wood, K., Wood, L., Worcester, E., Worcester, M., Wret, C., Wu, W., Xiao, Y., Yang, G., Yang, T., Yershov, N., Yonehara, K., Young, T., Yu, B., Yu, J., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zazueta, L., Zeller, G., Zennamo, J., Zeug, K., Zhang, C., Zhao, M., Zhivun, E., Zhu, G., Zimmerman, E. D., Zito, M., Zucchelli, S., Zuklin, J., Zutshi, V., and Zwaska, R.
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detector: technology ,deep underground detector [neutrino] ,530 Physics ,Physics::Instrumentation and Detectors ,Data management ,media_common.quotation_subject ,far detector ,Long baseline neutrino experiment CP violation ,01 natural sciences ,030218 nuclear medicine & medical imaging ,Neutrino oscillations. Neutrino Detectors. CP violation. Matter stability ,design [detector] ,03 medical and health sciences ,neutrino ,neutrino: deep underground detector ,0302 clinical medicine ,near detector ,0103 physical sciences ,Deep Underground Neutrino Experiment ,ddc:610 ,Neutrino oscillation ,Instrumentation ,detector: design ,Mathematical Physics ,activity report ,media_common ,010308 nuclear & particles physics ,business.industry ,Detector ,Volume (computing) ,Modular design ,time projection chamber: liquid argon ,Universe ,technology [detector] ,liquid argon [time projection chamber] ,Systems engineering ,High Energy Physics::Experiment ,Neutrino oscillations, DUNE technical design report, executive summary, detector technologies ,data management ,Neutrino ,business - Abstract
Journal of Instrumentation 15(08), T08008 (1-228) (2020). doi:10.1088/1748-0221/15/08/T08008, The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay—these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE's physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology., Published by Inst. of Physics, London
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- 2020
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34. Peripartum management of patient with long QT3 after successful implantable cardioverter defibrillator device discharge resulting in device failure: a case report
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Melissa J Lee, Danielle Monteil, and Michael T Spooner
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medicine.medical_specialty ,ICD discharge ,business.industry ,Long QT3 syndrome ,Mexiletine ,Ehjcr/30 ,Ehjcr/61 ,Life-Vest ,medicine ,case report ,AcademicSubjects/MED00200 ,Cardiology and Cardiovascular Medicine ,Intensive care medicine ,business ,Peripartum management ,Device failure - Abstract
Background Long QT3 syndrome type 3 (LQT3) is a gain of function mutation of the SCN5A gene that is inherited in an autosomal dominant fashion. Long QT3 syndrome type 3 results in an increase in arrhythmic events during rest, sleep, and bradycardia by extending the QT interval and inducing Torsades de pointes and sudden cardiac death. Attempting to block the sodium channel with Class I anti-arrhythmics or blocking adrenergic tone with beta-blockers especially in women has shown to be beneficial. There have been few large-scale studies on treating patients with LQT3 due to its lethality and underreported number of cases. Specifically, the safety and efficacy of pharmacologic treatment in pregnant LQT3 patients are unknown. Case summary This case demonstrates the safe use of Mexiletine and Propranolol in a 3rd-trimester pregnant LQT3 patient after a presumed ventricular arrhythmia and device-lead electrical short from therapy rendered her implantable cardioverter defibrillator inoperable in a VVI mode (venticular demand pacing). With appropriate medications, the patient was safely monitored through the remainder of her pregnancy and safely delivered at 36 weeks of pregnancy a healthy baby girl. The daughter, heterozygous for LQT3, showed no evidence of intrauterine growth restriction or other side effects from the medications. Discussion There are many variants of the SCN5A gene mutations that can lead to different phenotypes and not all mutations are responsive to the same medications. In this case, Mexiletine and Propranolol, both of which have only recently shown to benefit certain variants or LQT3 respectively, were safely started during the 3rd trimester of pregnancy without harming the foetus.
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- 2021
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35. The Use of Different Sepsis Risk Stratification Tools on the Wards and in Emergency Departments Uncovers Different Mortality Risks: Results of the Three Welsh National Multicenter Point-Prevalence Studies
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Harry J. A. Unwin, MBBCh, BSc, Maja Kopczynska, MBBCh, BSc, Richard Pugh, FRCA, Laura J. P. Tan, MBBS, BSc, Christian P. Subbe, MD, Gemma Ellis, MSc, Paul Morgan, FRCA, Peter Havalda, MD, Ben Sharif, MBBCh, John Burke, MSc, Tamas Szakmany, MD, PhD, FCCM, on behalf of Welsh Digital Data Collection Platform (WDDCP) Collaborators, Maria Hobrok, Moriah Thomas, Annie Burden, Nadia Youssef, Katherine Carnegie, Helena Colling-Sylvester, Natasha Logier, Meshari Alsaeed, Hannah Williams, Arfa Ayob, Nor Farzana, Sweta Parida, David Lawson, Emily Evans, Laura Jane Davis, Billie Atkins, Llywela Wyn Davies, Lee Sanders-Crook, Steffan Treharne Seal, Alice Cains, Richard Pugh, Katy Crisp, Sarah Venning, Ella Sykes, Stephanie Narine, Georgia Parry, Emily Angela Dillon, Qi Zhuang Siah, Ting Yang, Tyler Jones, Parvathi Thara, Emma Wood, Lara Wirt, Georgina St Pier, Richard Betts, Kyriaki Mitsaki, Mari Tachweed Pierce, Sioned Davies, Yakeen Hafouda, Erin Ifan, Grace Lacey, Francesca Mitchell, John Lynch, Michal Mazur, Lezia D’Souza, Bethan Ponting, Terrance Lau, Ruairidh Kerrigan, Lucy Morgan, Roshan Vindla, Claudia Zeicu, Becky James, Amirah Amin Ariff, Wan Binti Wan Azzlan, Charlotte Collins, Elizabeth Wickens, Alisa Norbee, Aliya Zulkefli, Thomas Haddock, Megan Thomas, Matthew Lee, Miriam Cynan, Nik-Syakirah Nik Azis, Imogen Hay, Catherine Russell, Margriet Vreugdenhil, Mustafa Abdimalik, Joseph Davies, Peter Havalda, Angharad Evans, Kate Robertson, Grace Gitau, Mei-yin Gruber, Thomas Telford, Anas Qarout, Naomi Nandra, Hannah Garrard, James Cutler, Rhiannon Tammy Jones, Amy Prideaux, Timothy Spence, Sarah Hardie, Harriet Seymour, Sam Willis, Matthew Warlow, Shanali Thanthilla, Thomas Downs, Nina Foley, Chad McKeown, Akshita Dandawate, Holleh Shayan-Arani, Ellie Taylor, Oliver Kyriakides, Rachel Price, Ffion Haf Mackey, Emily Haines, Samuel Chun, Nilarnti Vignarajah, Tessa Chamberlain, Dongying Zhao, Nayanatara Nadeesha T Tantirige, Naomi Dennehey, Georgina Evans, John Watts, Ceri Battle, Ryan Jones, Selina Jones, Charlotte James, James O’Hanlon, Isabella Bridges, Bethany Hughes, Leo Polchar, Elise Bisson, Charlotte Mykura, Lara Money, Joshua McKenna, Sarah Kinsman, Demiana Hanna, Emily Baker, Harrison Sprague, Liam Sharma, Tom Pontin, Emma Shore, Tamara Hughes, Sam Nightingale, Philby Baby, Matthew Shield, Alice Cross, Jenna Boss, Olivia Ross, George Ashton, Kimaya Pandit, Daniel Davies, Cameron Garbutt, Charlotte Johnston, Marcus Cox, Chantal Roberts, Alessia Waller, Laura Heekin, Kathy Wang, Rhianna Church, Shrina Patel, Marianne Broderick, Hannah Whillis, Daniel Craig Hathaway, Emel Yildirim, Caitlin Atkins, Elin Walters, Carys Durie, Robert James Hamilton Sinnerton, Benjamin Tanner, Julimar Abreu, Kiran Bashir, Vincent Hamlyn, Amelia Tee, Zoe Ann Hinchcliffe, Rita Otto, Georgie Covell, Megan Stone, Victoria Maidman, Katherine Godfray, Rhidian Caradine, Hannah Beetham, Adanna Nicole Anomneze-Collins, Jeanette Tan, Yasmina Abdelrazik, Azizah Khan, Nabihah Malik, Aidan Clack, Lewis Oliva, Tyler Thomas, Adam George Mounce, Anoopama Ramjeeawon, Ndaba Mtunzi, Duncan Soppitt, Jay Hale, Jack Wellington, Robert Buchanan Ross, Danielle Lis, Rebecca Parsonson, Jude Joseph-Gubra, Ajitha Arunthavarajah, Jessica Nicholas, Aaron Harris, Henry Atkinson, Jessica Webster, Tim Burnett, Josephine Raffan Gowar, Sam DeFriend, Jasmine Whitaker, Elizabeth Beasant, Luis Macchiavello, Danyal Usman, Abdullah Mahdi, Tiffany Ye Tze Shan, Nick Savill, Jennifer Gee, Lizzie Hodges, Ami Desai, Hannah Rossiter, Matthew Taylor, Kevin Pinto, Eleanor Hartley, Oscar Emanuel, Rhiannon Long, Megan Selby, Elilis Wardle, Alexandra Urquhart, Jack Barrington, Matthew Ashman, Elizabeth Adcock, Amelia Dickinson, Rebecca Jordache, Rym Chafai El Alaoui, Sophie Stovold, Sam Vickery, Nia Jones, Alice O’Donnell, Monty Cuthbert, Osa Eghosa, Muhammad Karim, Lowri Williams, Louise Tucker, Tom Downs, Rebecca Walford, Annabelle Hook, Adam Mounce, Emily Eccles, Ross Edwards, Kirtika Ramesh, Charlie Hall, Maria Lazarou, Rhidian Jones, Katy McGillian, Hari Singh Bhachoo, Zoe The, Vithusha Inpahas, Ruchi Desai, Yusuf Cheema, Andrew Hughes, Olivia Cranage, Felicity Bee, Khalid Osman, Humza Khan, Jennifer Pitt, Charlotte Pickwick, Jorge Carter, Fiona Andrew, Naseera Seedat, Roshni Patel, Megan Walker, Alicia Boam, Jessica Randall, Beth Bowyer, Josh Edwards, Natasha Jones, Emma Walker, Ailsa MacNaught, Swagath Balachandran, Abbie Shipley, Jennifer Louise Kent, Samuel Tilley, Bethany Davies, Emma Withers, Krishna Parmar, Lucie Webber, Angelica Sharma, Amy Handley, Alexandra Gordon, Lucy Allen, Rebecca Paddock, Harriet Penney, Lopa Banerjee, Chloe Victoria Vanderpump, Kate Harding, John Burke, Orsolya Minik, Nia Jarrett, Ellie Rowe, Adanna Anomneze-Collins, Harry Griffiths, Sarah Pengelly, Ffion Bennett, Ahmed Bilal, Abdullah El-badawey, Bethan Ellis, Luke Cook, Harriet Elizabeth Valentine Maine, Kiri Armstrong, Hannah Beresford, Timia Raven-Gregg, Tom Liddell-Lowe, Caitlin Ong, Harriet Reed, Frederika Alice St John, Weronika Julia Kozuch, Isabelle Ray, Irukshi Anuprabha Silva, Sin Ting Natalie Cheng, Umme-Laila Ali, Noreena Syed, Luke Murphy, Thomas Grother, Harry Smith, Rachel Watson, Omar Marei, Emma Kirby, Anna Gilfedder, Lydia Maw, Sarah O’Connor, Charlotte Maden, Helena Jones, Hazel Preston, Nur Amirah Binti Maliki, Mark Zimmerman, Jessica Webber, Llewelyn Jones, Rebecca Phillips, Lauren McCarthy, Emily Hubbard, Leo Duffy, Abigail Guerrier Sadler, Tamas Szakmany, Owen Richards, Charles King, Charlotte Killick, Yusuf Chema, Kavita Shergill, Yi Huen, Lillian Lau, Hannah Mustafa Ali, Lucas Wilcock, Molly Timlin, Ayeesha Rela, Daniel Smith, Sarah Ireland, Jennifer Evans, Nayanatara Poobalan, Jessica Pearce, Thivya V Vadiveloo, Zoe Black, Daniel Elis Samuel, Humaira Hussain, Joanna Hawkins, Zeid Atiyah, Rebecca Creamer, Maham Zafar, Ahmad Almazeedi, Hannah Brunnock, Zain Nasser, Mekha Jeyanthi, Poorya Moghbel, Katie Kwan, Isobel Sutherland, Frank Davis, Abigail Rogers, Zhao Xuan Tan, Clare Chantrill, Amal Robertson, Jonathan Foulkes, Rahana Khanam, Jomcy John, Sarah Hannah Meehan, Huria Metezai, Hannah Dawson, Navrhinaa Vadivale, Camilla Lee, Amrit Dhadda, Sian Cleaver, Genna Logue, Joy Inns, Isabel Jones, Robyn Howcroft, Carys Gilbert, Matthew Bradley, Louise Pike, Rachel Keeling, Charldré Banks, Eleanor Cochrane, James McFadyen, Matthew Mo, Emily Ireland, Esme Brittain, Ihssen Laid, Charlotte Green, Adriel Mcforrester, Xuong Michelle Ly, Mariana Nalbanti, Raven Joseph, Jack Tagg, David Purchase, Pan Myat, Ayako Niina, Tyler Joshua Jones, Lowri Hughes Thomas, Natalie Hoyle, Patrick Benc, Ellen Davies, Meng-Chieh Wu, David Fellows, Sam Tilley, Eloise Baxendale, Karishma Khan, Andrew Forrester, Oliver Moore, Hse Juinn Lim, Aimee Owen, Faris Hussain, Nima-banu Allybocus, Maneha Sethi, Harry Waring, Adeel Khan, Claire Smith, Nicholas Doyle, Mohammad Yahya Amjad, Luke Galloway, Paul Morgan, Gemma Ellis, Robert Lundin, Haamed Al Hassan, Bethan Markall, Namratha Kaur, Emmanuel Onyango, Heather Beard, Elliot Field, Ellen Nelson-Rowe, Lizzie Adcock, Amelia Stoddart, Frederika St John, Mathoorika Sivananthan, Rhys Jones, Sung Yeon Kwak, Lily Farakish, Holly Rhys-Ellis, Kate Moss, Tallulah Ray, Tessa David, Talea Roberts, Annie Quy, Aniket Paranjape, Nutchanun Poolworaluk, Mary Keast, Si Liang Yao, Dion Manning, Isobel Irwin, Umair Asim, Emelia Boggon, Ibrahim Alkurd, Genevieve Lawerece, Jade Brown, Emily Murphy, Evie Lambert, Jeremy Guilford, Beth Payne, Mariam Almulaifi, Arwel Poacher, Sashiananthan Ganesananthan, Berenice Cunningham-Walker, Chloe Spooner, Akanksha Kiran, Nabeegh Nadeem, Vidhi Unadkat, Esme Sparey, David Li, Jessica Smith, India Corrin, Amit Kurani, Paul McNulty, Ceri Brown, Wojciech Groblewski, Szilvia Szoke, Amelia Redman, Esther McKeag, Anastasia Donnir, Gaautham Ravishangar, Emanuela Howard, Charlotte Salmon, Sara Tanatova, Jasmine Kew, Megan Eilis Clark, Ellen Hannay, Olesya Godsafe, Christina Houghton, Francesca Lavric, Rachel Mallinson, Chris Littler, Harsha Reddy, Andrew Campbell, Benedict Soo, Rachel Evans, Georgina Donowho, Alexandra Cawthra, Maddison Davies, Matthew Lawrence Ashman, Jamie Scriven, James Vautrey, Shannon Seet, Imogen Britton, Abigail Hodgson, Emma Twohey, Joseph Robbins, Vanessa Yeo Yung Ling, Kimiya Asjadi, Carven Chin Yee Shean, Zoe McCarroll, Oritseweyimi Amatotsero, Hei Man Priscilla Chan, John Ng Cho Hui, Antonia Ashaye, Josephine Acheampong, Ayowade Adeleye, Saber Ahmed, Alexandra Chrysostomou, Harry Unwin, Eshen Ang, Niamh McSwiney, Yin Yin Lim, Zong Xuan Lee, Svetlana Kulikouskaya, Nur Zulkifili, Sheryl Lim, Lim Xin, Adiya Urazbayeva, Nur Haslina Ahmad Hanif, Yau Ke Ying, Alice Coleclough, Eilis Higgins, Naomi Spencer, Tze Gee Ng, Sam Booth, Stephanie Wai Yee Ng, Christian P Subbe, Isabella Patterson, Wen Li Chia, Abdullah Mukit, Hei Yi Vivian Pak, Felicity Lock, Mariana Nalmpanti, Shôn Alun Thomas, Tanisha Burgher, Alfred Wei Zhen Yeo, Siwan Powell Jones, Charlie Miles, Millicent Perry, Holly Burton, Katharine Powell, Luthfun Nessa, Aalaa Fadlalla, Rhian Morgan, Elizabeth Hodges, Amelia Heal, Chloe Scott, Alice Tayler, Thomas Chandy, Abduahad Taufik, James Cochrane, Samuel Willis, Sieh Yen Heng, Alex Cooper, Henrik Graf von der Pahlen, Isabella Talbot, Robin Gwyn Roberts, Jessica Sharma Smith, Aisling Sweeney, Cerian Roberts, Laura Bausor, Chania, Daniah Thomas, Elen Wyn Puw, Ronan A Lyons, and Judith E Hall
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red flag ,medicine.medical_specialty ,media_common.quotation_subject ,Concordance ,Prevalence ,Sepsis ,sepsis ,Sequential Organ Failure Assessment ,Excellence ,medicine ,Risk of mortality ,Original Clinical Report ,National Institute of Clinical Excellence ,media_common ,business.industry ,RC86-88.9 ,Medical emergencies. Critical care. Intensive care. First aid ,General Medicine ,Emergency department ,medicine.disease ,mortality ,Systemic inflammatory response syndrome ,systemic inflammatory response syndrome ,Emergency medicine ,Risk stratification ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,business - Abstract
Supplemental Digital Content is available in the text., OBJECTIVES: To compare the performance of Sequential Organ Failure Assessment, systemic inflammatory response syndrome, Red Flag Sepsis, and National Institute of Clinical Excellence sepsis risk stratification tools in the identification of patients at greatest risk of mortality from sepsis in nonintensive care environments. DESIGN: Secondary analysis of three annual 24-hour point-prevalence study periods. SETTING: The general wards and emergency departments of 14 acute hospitals across Wales. Studies were conducted on the third Wednesday of October in 2017, 2018, and 2019. PATIENTS: We screened all patients presenting to the emergency department and on the general wards. MEASUREMENTS AND MAIN RESULTS: We recruited 1,271 patients, of which 724 (56.9%) had systemic inflammatory response syndrome greater than or equal to 2, 679 (53.4%) had Sequential Organ Failure Assessment greater than or equal to 2, and 977 (76.9%) had Red Flag Sepsis. When stratified according to National Institute of Clinical Excellence guidelines, 450 patients (35.4%) were in the “High risk” category in comparison with 665 (52.3%) in “Moderate to High risk” and 156 (12.3%) in “Low risk” category. In a planned sensitivity analysis, we found that none of the tools accurately predicted mortality at 90 days, and Sequential Organ Failure Assessment and National Institute of Clinical Excellence tools showed only moderate discriminatory power for mortality at 7 and 14 days. Furthermore, we could not find any significant correlation with any of the tools at any of the mortality time points. CONCLUSIONS: Our data suggest that the sepsis risk stratification tools currently utilized in emergency departments and on the general wards do not predict mortality adequately. This is illustrated by the disparity in mortality risk of the populations captured by each instrument, as well as the weak concordance between them. We propose that future studies on the development of sepsis identification tools should focus on identifying predicator values of both the short- and long-term outcomes of sepsis.
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- 2021
36. Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study
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Richard J Perry, Arina Tamborska, Bhagteshwar Singh, Brian Craven, Richard Marigold, Peter Arthur-Farraj, Jing Ming Yeo, Liqun Zhang, Ghaniah Hassan-Smith, Matthew Jones, Christopher Hutchcroft, Esther Hobson, Dana Warcel, Daniel White, Phillip Ferdinand, Alastair Webb, Tom Solomon, Marie Scully, David J Werring, Christine Roffe, Sara Al-izzi, Aravindhan Baheerathan, Soma Banerjee, Gary Benson, Claudia Boshier, Sandeep Buddha, Nathan Burley, Ruaridh Cameron Smail, Arvind Chandratheva, Pavel Chudakou, Philip Clatworthy, Alasdair Coles, Thomas Cox, Ranjit Dasgupta, Richard Davenport, Darrell Devine, Stephen Fenlon, Carolyn Gabriel, Rita Ghatala, Claire Hall, Milan Hargovan, Kirsty Harkness, Ian Harvey, Lucy Hicken, Laura Howaniec, Abubaker Ibnouf, Luis Idrovo, Gordon Ingle, Yong Kyan Lee, Ailidh Lang, Simon McBride, Malcolm McLeod, Ruth Medlock, Puja Mehta, Ian Morrison, Girish Muddegowda, Sharon Muzerengi, Donald Pang, Gopinath Periyasamy, Gavin Preston, Naomi Priestley, Lydia Revicka, Sadia Saber, Elliott Smith, Youssef Sorour, Oliver Spooner, Jon Stone, Laszlo Sztriha, Narmathey Thambirajah, Rhys Thomas, David Veale, Jasmine Wall, Sarah White, James White, Syarah Yusoff, Laura Zambreanu, Arthur-Farraj, Peter [0000-0002-1239-9392], and Apollo - University of Cambridge Repository
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Cerebral veins ,Adult ,Male ,medicine.medical_specialty ,COVID-19 Vaccines ,Context (language use) ,Cohort Studies ,Fibrin Fibrinogen Degradation Products ,Internal medicine ,medicine ,Blood test ,Humans ,Platelet ,Venous Thrombosis ,Purpura, Thrombocytopenic, Idiopathic ,medicine.diagnostic_test ,business.industry ,Platelet Count ,SARS-CoV-2 ,Comment ,Vaccination ,General Medicine ,Middle Aged ,medicine.disease ,Thrombosis ,United Kingdom ,Venous thrombosis ,Intracranial Thrombosis ,Female ,business ,Cohort study - Abstract
Background: A new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous thrombosis is the most common manifestation of this syndrome but, to our knowledge, has not previously been described in detail. We aimed to document the features of post-vaccination cerebral venous thrombosis with and without VITT and to assess whether VITT is associated with poorer outcomes. Methods: For this multicentre cohort study, clinicians were asked to submit all cases in which COVID-19 vaccination preceded the onset of cerebral venous thrombosis, regardless of the type of vaccine, interval between vaccine and onset of cerebral venous thrombosis symptoms, or blood test results. We collected clinical characteristics, laboratory results (including the results of tests for anti-platelet factor 4 antibodies where available), and radiological features at hospital admission of patients with cerebral venous thrombosis after vaccination against COVID-19, with no exclusion criteria. We defined cerebral venous thrombosis cases as VITT-associated if the lowest platelet count recorded during admission was below 150 × 109 per L and, if the D-dimer was measured, the highest value recorded was greater than 2000 μg/L. We compared the VITT and non-VITT groups for the proportion of patients who had died or were dependent on others to help them with their activities of daily living (modified Rankin score 3–6) at the end of hospital admission (the primary outcome of the study). The VITT group were also compared with a large cohort of patients with cerebral venous thrombosis described in the International Study on Cerebral Vein and Dural Sinus Thrombosis. Findings: Between April 1 and May 20, 2021, we received data on 99 patients from collaborators in 43 hospitals across the UK. Four patients were excluded because they did not have definitive evidence of cerebral venous thrombosis on imaging. Of the remaining 95 patients, 70 had VITT and 25 did not. The median age of the VITT group (47 years, IQR 32–55) was lower than in the non-VITT group (57 years; 41–62; p=0·0045). Patients with VITT-associated cerebral venous thrombosis had more intracranial veins thrombosed (median three, IQR 2–4) than non-VITT patients (two, 2–3; p=0·041) and more frequently had extracranial thrombosis (31 [44%] of 70 patients) compared with non-VITT patients (one [4%] of 25 patients; p=0·0003). The primary outcome of death or dependency occurred more frequently in patients with VITT-associated cerebral venous thrombosis (33 [47%] of 70 patients) compared with the non-VITT control group (four [16%] of 25 patients; p=0·0061). This adverse outcome was less frequent in patients with VITT who received non-heparin anticoagulants (18 [36%] of 50 patients) compared with those who did not (15 [75%] of 20 patients; p=0·0031), and in those who received intravenous immunoglobulin (22 [40%] of 55 patients) compared with those who did not (11 [73%] of 15 patients; p=0·022). Interpretation: Cerebral venous thrombosis is more severe in the context of VITT. Non-heparin anticoagulants and immunoglobulin treatment might improve outcomes of VITT-associated cerebral venous thrombosis. Since existing criteria excluded some patients with otherwise typical VITT-associated cerebral venous thrombosis, we propose new diagnostic criteria that are more appropriate.
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- 2021
37. Rejoinder
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Murat Kulahci, Abdul Rauf Khan, Georg Ørnskov Rønsch, Flavia Dalia Frumosu, and Max Peter Spooner
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business.industry ,Perspective (graphical) ,Big data ,Sociology ,Safety, Risk, Reliability and Quality ,business ,Industrial and Manufacturing Engineering ,Epistemology - Published
- 2020
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38. Regional variation in practitioner employment in general practices in England: a comparative analysis
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Imelda McDermott, Mark Hann, Damian Hodgson, Jon Gibson, Kath Checkland, Sharon Spooner, Matt Sutton, and Anne Mcbride
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Employment ,Primary care ,health workforce ,03 medical and health sciences ,0302 clinical medicine ,Healthcare delivery ,Nursing ,General Practitioners ,statistics and numerical data ,Medicine ,Humans ,Healthcare workforce ,030212 general & internal medicine ,Health policy ,general practice ,Primary Health Care ,business.industry ,030503 health policy & services ,Research ,primary care networks ,United Kingdom ,Regional variation ,Software deployment ,Workforce ,Health education ,0305 other medical science ,Family Practice ,business - Abstract
BackgroundIn recent years, UK health policy makers have responded to a GP shortage by introducing measures to support increased healthcare delivery by practitioners from a wider range of backgrounds.AimTo ascertain the composition of the primary care workforce in England at a time when policy changes affecting deployment of different practitioner types are being introduced.Design and settingThis study was a comparative analysis of workforce data reported to NHS Digital by GP practices in England.MethodStatistics are reported using practice-level data from the NHS Digital June 2019 data extract. Because of the role played by Health Education England (HEE) in training and increasing the skills of a healthcare workforce that meets the needs of each region, the analysis compares average workforce composition across the 13 HEE regions in EnglandResultsThe workforce participation in terms of full-time equivalent of each staff group across HEE regions demonstrates regional variation. Differences persist when expressed as mean full-time equivalent per thousand patients. Despite policy changes, most workers are employed in long-established primary care roles, with only a small proportion of newer types of practitioner, such as pharmacists, paramedics, physiotherapists, and physician associates.ConclusionThis study provides analysis of a more detailed and complete primary care workforce dataset than has previously been available in England. In describing the workforce composition at this time, the study provides a foundation for future comparative analyses of changing practitioner deployment before the introduction of primary care networks, and for evaluating outcomes and costs that may be associated with these changes.
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- 2020
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39. Review of metastatic colorectal cancer treatment pathways and early clinical experience of trifluridine/tipiracil in the UK named patient programme
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Kai-Keen Shiu, Clare Spooner, Saifee Mullamitha, Daniel Stevens, Angela M. Carter, and Timothy Iveson
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0301 basic medicine ,Male ,Cancer Research ,Pyrrolidines ,Organoplatinum Compounds ,Leucovorin ,Trifluridine ,chemistry.chemical_compound ,0302 clinical medicine ,FOLFOX ,Antineoplastic Combined Chemotherapy Protocols ,Neoplasm Metastasis ,education.field_of_study ,metastatic colorectal cancer ,Middle Aged ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Drug Combinations ,Treatment Outcome ,Oncology ,030220 oncology & carcinogenesis ,FOLFIRI ,Female ,Fluorouracil ,Colorectal Neoplasms ,treatment pathways ,medicine.drug ,Research Article ,medicine.medical_specialty ,trifluridine and tipiracil ,Population ,named patient programme ,lcsh:RC254-282 ,Capecitabine ,03 medical and health sciences ,disease progression ,Internal medicine ,Genetics ,medicine ,Humans ,education ,Uracil ,Tipiracil ,Aged ,treatment duration ,real-world data ,business.industry ,United Kingdom ,Oxaliplatin ,Irinotecan ,030104 developmental biology ,chemistry ,Camptothecin ,business ,Thymine - Abstract
Background The standard first- and second- line chemotherapy backbone regimens for metastatic colorectal cancer (mCRC) are 5-fluorouracil (5-FU)/capecitabine-based with addition of irinotecan or oxaliplatin. Until recently, evidence for optimal sequencing post second-line was sparse. Trifluridine/tipiracil (indicated for mCRC and gastric cancer after standard chemotherapies) was made available to UK patients via a named patient programme (NPP) before receiving marketing authorisation in Europe in 2016, allowing characterisation of UK treatment pathways, and evaluation of trifluridine/tipiracil in a UK non-trial population. Methods Data collected routinely for the NPP were analysed to describe the patient demographics, clinical characteristics and treatment pathways. Patients eligible for the programme were adults (≥18 years) with histologically or cytologically confirmed mCRC who had previously received chemotherapy treatment(s). Results Of the 250 eligible patients enrolled in the NPP, 194 patients received ≥1 dose of trifluridine/tipiracil and 56 patients did not receive trifluridine/tipiracil. The following results are reported first for patients who received trifluridine/tipiracil and second for those who did not receive trifluridine/tipiracil: median (IQR) age was 63.0 (54.0–69.0) and 62.0 (54.8–69.0) years; Eastern Cooperative Oncology Group performance status score was 0 for 28 and 14%, 1 for 65 and 70%, 2 for 7 and 16%. In terms of previous systemic treatments 47 and 43% had 2 prior lines of therapy. FOLFOX-, FOLFIRI- and CAPOX-based therapies were the most common first-line regimens in patients receiving trifluridine/tipiracil (37, 35 and 21%, respectively), and in patients not receiving trifluridine/tipiracil (41, 30 and 20%, respectively). Second-line treatment regimens in patients receiving and not receiving trifluridine/tipiracil were most commonly FOLFIRI-based (48 and 41%, respectively) and FOLFOX-based (19 and 21%, respectively). Patients received a median of 2 cycles of trifluridine/tipiracil with a median treatment duration of 1.8 (95% CI: 1.8–2.4) months. In patients who discontinued treatment due to disease progression, the median progression-free duration was 2.8 (95% CI: 2.4–2.9) months. Conclusions The results highlight the number of treatment pathways used to treat mCRC in routine UK clinical practice prior to the marketing authorisation and National Institute for Health and Care Excellence approval of trifluridine/tipiracil and highlight the lack of clinical guidelines for mCRC.
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- 2020
40. Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion
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Thomas Hong, Andrew Chang, Samantha Fraser-Bell, and Kimberly Spooner
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Male ,Vascular Endothelial Growth Factor A ,medicine.medical_specialty ,Visual acuity ,Original Clinical Study ,Bevacizumab ,genetic structures ,Recombinant Fusion Proteins ,Drug Resistance ,Visual Acuity ,Angiogenesis Inhibitors ,Macular Edema ,Ophthalmology ,Ranibizumab ,Retinal Vein Occlusion ,medicine ,Humans ,Prospective cohort study ,Macular edema ,Aflibercept ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,switching ,Drug Substitution ,aflibercept ,Retrospective cohort study ,General Medicine ,Diabetic retinopathy ,Middle Aged ,medicine.disease ,eye diseases ,Receptors, Vascular Endothelial Growth Factor ,Treatment Outcome ,anti-VEGF ,Intravitreal Injections ,Female ,sense organs ,medicine.symptom ,business ,Tomography, Optical Coherence ,medicine.drug - Abstract
Purpose: The aim of this study was to examine 12-month outcomes of eyes switched from intravitreal ranibizumab or bevacizumab to aflibercept for cystoid macular edema due to retinal vein occlusion (RVO). Design: Retrospective, observation, case series. Methods: A retrospective study was performed assessing eyes with RVO switched to aflibercept for at least 12 months. To be included in the study, eyes had to have macular edema despite treatment for at least 6 months with bevacizumab and/or ranibizumab before the switch, central foveal thickness (CFT) ≥300 μm at time of switch, and visual acuity (VA) ≤60 early treatment of diabetic retinopathy score (ETDRS) letters (20/40 Snellen equivalent). Outcome measures included change in VA (in ETDRS letters), CFT, and interval between intravitreal injections. Results: 27 eyes of 27 patients were included in the analysis: 13 with branch RVO, and 14 with central RVO. Mean VA before switch was 54.2 ± 23.7 letters (20/80 Snellen equivalent) and mean CFT was 460.4 ± 178.2 μm. Mean number of previous anti-vascular endothelial growth factor (VEGF) injections was 29.5 ± 19.2. At 12 months, mean VA improved by 8.7 ± 13.2 letters (P
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- 2020
41. A practical review of shorter than excitation wavelength light emission processes
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David J. Ottaway, T. J. de Prinse, Nigel A. Spooner, Jillian E. Moffatt, Elizaveta Klantsataya, and Georgios Tsiminis
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Physics ,Excitation wavelength ,Photon ,business.industry ,010401 analytical chemistry ,Physics::Optics ,Nonlinear optics ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Two-photon absorption ,Photon upconversion ,0104 chemical sciences ,Optics ,Light emission ,Excited state absorption ,0210 nano-technology ,business ,Instrumentation ,Spectroscopy - Abstract
Shorter-than-excitation-wavelength (STEW) optical emissions, where photons originating in a material have higher energies than those that created them, have in the past few decades become important...
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- 2019
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42. Trends in GP incomes in England, 2008–2017: a retrospective analysis of repeated postal surveys
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Sharon Spooner, Jonathan Gibson, Rose Atkins, Katherine Checkland, and Matt Sutton
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Inflation ,Attractiveness ,Attitude of Health Personnel ,media_common.quotation_subject ,education ,General Practice ,Job Satisfaction ,health workforce ,03 medical and health sciences ,0302 clinical medicine ,General Practitioners ,Retrospective analysis ,Humans ,Medicine ,030212 general & internal medicine ,Retrospective Studies ,media_common ,Career Choice ,Salaries and Fringe Benefits ,business.industry ,Research ,030503 health policy & services ,Professional Practice Location ,income ,Annual income ,England ,General practice ,Income ,Global Positioning System ,Health Services Research ,0305 other medical science ,Family Practice ,business ,hours ,Demography - Abstract
BackgroundThere is widespread concern over the recruitment and retention of GPs in England. Income is a fundamental consideration affecting the attractiveness of working in general practice.AimTo report on trends in average incomes earned by GPs in England, adjusted for inflation and contracted time commitment.Design and settingPostal surveys of random samples of GPs working in England in 2008, 2010, 2012, 2015, and 2017.MethodTrends in average reported incomes of partner and salaried GPs were directly standardised for the reported number of sessions worked per week and adjusted for inflation.ResultsData were obtained from between 1000 and 1300 responders each year, representing response rates between 25% and 44%. Almost all responders (96%) reported the income they earned from their job as a GP. Mean nominal annual income decreased by 1.1% from £99 437 in 2008 to £98 373 in 2017 for partner GPs and increased by 4.4% from £49 061 to £51 208 for salaried GPs. Mean sessions worked decreased from 7.7 to 7.0 per week for partner GPs and decreased from 5.6 to 5.3 per week for salaried GPs. Mean income adjusted for sessions worked and inflation decreased by 10.0% for partner GPs and by 7.0% for salaried GPs, between 2008 and 2017.ConclusionThe decrease in GP income adjusted for sessions worked and inflation over the last decade may have contributed to the current problems with recruitment and retention.
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- 2019
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43. Technologies of Governance in Context: Four Global Windows Into Neoliberalism and Audit Culture in Higher Education
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Marc Spooner
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Higher education ,business.industry ,Neoliberalism (international relations) ,Corporate governance ,05 social sciences ,050301 education ,Context (language use) ,06 humanities and the arts ,Audit ,Public administration ,060202 literary studies ,New public management ,Anthropology ,Political science ,0602 languages and literature ,business ,0503 education ,Social Sciences (miscellaneous) - Abstract
This partial special issue of Qualitative Inquiry, titled “Technologies of Governance in Context: Four Global Windows Into Neoliberalism and Audit Culture in Higher Education,” examines various aspects of the academic impact of neoliberal technologies from four context-specific locations that include Australia, Mexico, the United Kingdom, and the United States, in addition to my own Canadian perspective in this introduction. It is based on a similarly themed plenary panel that was held in 2018 as part of the 14th Annual International Congress of Qualitative Inquiry at University of Illinois, Urbana–Champaign titled “The Politics, Places, Forms, and Effects of Accountability, Quality Assurance, and/or Excellence Frameworks in these Global Troubled Times.”
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- 2019
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44. Burden Of Treatment Among Patients Undergoing Intravitreal Injections For Diabetic Macular Oedema In Australia
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Kimberly Spooner, Saskia Koller, Thomas Hong, Andrew Chang, and Gerry Guinan
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Pharmacology ,medicine.medical_specialty ,Medical treatment ,business.industry ,Incidence (epidemiology) ,Injection therapy ,030209 endocrinology & metabolism ,030204 cardiovascular system & hematology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetic macular oedema ,Quality of life ,Diabetes mellitus ,Health care ,Emergency medicine ,Internal Medicine ,Medicine ,Survey data collection ,business - Abstract
Aim The incidence and prevalence of diabetes mellitus (DM) in Australia is increasing. Thus, it is essential that practitioners appreciate the impending effect that increasing incidence of diabetes has on patients and the wider community. Accordingly, this study examines the humanistic burden of intravitreal injections for the treatment of diabetic macular oedema (DMO) among several health variables. Methods Survey data from a representative sample of Australian adults undergoing treatment for DMO were examined. Respondents participated via an online survey recruited by means of a national online consumer panel and the New South Wales and Victorian Diabetes Foundations. The online survey included questions relating to the humanistic burden of disease, such as the emotional and physical impact of intravitreal injection therapy; the practical impacts of injection therapy; and to identify potential improvements to treatment regimens. Results Sixty-five participants took part in the online survey. Of these, 49% had their most recent injection
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- 2019
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45. A fibre optic based approach and device for sensing beta radiation in liquids
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Heike Ebendorff-Heidepriem, Nigel A. Spooner, Christopher A. G. Kalnins, David J. Ottaway, and Carly A. Whittaker
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Optical fiber ,Materials science ,Transmission loss ,02 engineering and technology ,Radiation ,01 natural sciences ,law.invention ,law ,0103 physical sciences ,Electrical and Electronic Engineering ,Instrumentation ,010302 applied physics ,Scintillation ,Range (particle radiation) ,Nuclear fuel ,business.industry ,Metals and Alloys ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Beta (plasma physics) ,Storage tank ,Optoelectronics ,0210 nano-technology ,business - Abstract
An optical fibre-based beta radiation sensing device has been investigated for the purpose of detecting low levels of the daughter products of Uranium-238 in liquids for mineral processing and environmental monitoring applications. The sensor operates by detecting the scintillation light produced by polymer optical fibres. A range of fibres have been studied by quantifying a number of properties that are critical to their performance including the beta radiation scintillation response, transmission loss, and performance under the proposed environmental conditions. Based on these measurements, the most suitable fibre type was incorporated within a prototype sensing device which is capable of performing direct, real-time, continuous measurements of beta radiation emitting radionuclides within solutions or suspensions, which is not possible with current measurement techniques. The technology presented here allows for the detection of low levels of beta radiation in liquids, which could be useful for the detection of radiation in mineral processing liquids, municipal water sources, and storage tanks containing nuclear fuel.
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- 2019
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46. Feedback at the Point of Care to Decrease Medication Alert Rates in an Electronic Health Record
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Emrah Gecili, Thomas Minich, P. J. Van Camp, S. Andrew Spooner, Judith W. Dexheimer, Eric S. Kirkendall, Philip A. Hagedorn, and Michal Kouril
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Pediatric emergency ,Drug-Related Side Effects and Adverse Reactions ,Point-of-Care Systems ,Reminder Systems ,MEDLINE ,Clinical decision support system ,Medical Order Entry Systems ,Feedback ,03 medical and health sciences ,0302 clinical medicine ,Salience (neuroscience) ,Electronic health record ,030225 pediatrics ,Electronic Health Records ,Humans ,Medication Errors ,Medicine ,Prospective Studies ,Child ,Point of care ,business.industry ,030208 emergency & critical care medicine ,General Medicine ,Decision Support Systems, Clinical ,medicine.disease ,Pediatrics, Perinatology and Child Health ,Emergency Medicine ,Feasibility Studies ,Medical emergency ,Emergency Service, Hospital ,business - Abstract
Frequently overridden alerts in the electronic health record can highlight alerts that may need revision. This method is a way of fine-tuning clinical decision support. We evaluated the feasibility of a complementary, yet different method that directly involved pediatric emergency department (PED) providers in identifying additional medication alerts that were potentially incorrect or intrusive. We then evaluated the effect subsequent resulting modifications had on alert salience. Methods We performed a prospective, interventional study over 34 months (March 6, 2014, to December 31, 2016) in the PED. We implemented a passive alert feedback mechanism by enhancing the native electronic health record functionality on alert reviews. End-users flagged potentially incorrect/bothersome alerts for review by the study's team. The alerts were updated when clinically appropriate and trends of the impact were evaluated. Results More than 200 alerts were reported from both inside and outside the PED, suggesting an intuitive approach. On average, we processed 4 reviews per week from the PED, with attending physicians as major contributors. The general trend of the impact of these changes seems favorable. Discussion The implementation of the review mechanism for user-selected alerts was intuitive and sustainable and seems to be able to detect alerts that are bothersome to the end-users. The method should be run in parallel with the traditional data-driven approach to support capturing of inaccurate alerts. Conclusions User-centered, context-specific alert feedback can be used for selecting suboptimal, interruptive medication alerts.
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- 2019
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47. The influence of training experiences on career intentions of the future GP workforce: a qualitative study of new GPs in England
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Louise Laverty, Sharon Spooner, and Katherine Checkland
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Medical education ,Attitude of Health Personnel ,media_common.quotation_subject ,General Practice ,education ,Specialty ,030204 cardiovascular system & hematology ,Recruitment and retention ,Job Satisfaction ,03 medical and health sciences ,0302 clinical medicine ,General Practitioners ,Qualitative research ,Humans ,Medicine ,Social media ,030212 general & internal medicine ,Qualitative Research ,media_common ,Career Choice ,Careers ,business.industry ,Specialty training ,Focus Groups ,Focus group ,England ,Workforce ,Thematic analysis ,General practice ,Family Practice ,business ,Publicity ,Situation analysis - Abstract
BackgroundThe capacity of the UK GP workforce has not kept pace with increasing primary care workloads. Although many doctors successfully complete GP specialty training programmes, some do not progress to work in NHS general practice.AimThis article explores the training experiences and perceptions of newly qualified GPs to understand how their education, training, and early experiences of work influence their career plans.Design and settingA qualitative study of doctors in their final year of GP training (ST3) and within 5 years of completion of GP training (F5).MethodParticipants across England were recruited through training programmes, First5 groups, and publicity using social media and networks. Open narrative interviews were conducted with individuals and focus groups. Audiorecorded interviews were transcribed, and a thematic analysis was supported by NVivo and situational analysis mapping techniques.ResultsFifteen participants engaged in individual interviews and 10 focus groups were carried out with a total of 63 participants. Most doctors reported that training programmes had prepared them to deal confidently with most aspects of routine clinical GP work. However, they felt underprepared for the additional roles of running a practice and in their understanding of wider NHS organisational structures. Doctors wished to avoid unacceptably heavy workloads and voiced concerns about the longer-term sustainability of general practice.ConclusionStrategies to attract and retain enough GPs to support delivery of comprehensive primary care should consider how doctors’ early career experiences influence their career intentions. A coherent plan is needed to improve their preparation and increase confidence that they can achieve a professionally satisfying, effective, and sustainable career in NHS general practice.
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48. Tolerating Subretinal Fluid in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Using a Treat-and-Extend Regimen
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Robyn H. Guymer, Caroline M. Markey, Ian L. McAllister, Mark C. Gillies, Alex P. Hunyor, Jennifer J. Arnold, Andrew Chang, Adil Syed, Geoffrey Broadhead, Thomas Pham, Thomas Hong, Lily Wong, Meidong Zhu, Shelley Burnett, Nichole Joachim, Wijeyanthy Wijeyakumar, Gabriel Manalang, Cleopatra Mhlanga, Nicole Joachim, Kimperly Spooner, Paul Mitchell, Suriya Foran, Christabel Wilson, Victoria Cossatto, Laskshmi Waniganayke, Vivien Mai, Rabiya Atif, Lakshmi Wa, Sapna Maharaj, David Liong, Christine Matic, Katherine Tran, Sheenal Jas, Danielle Gibbs, Sanj Wickremasinghe, Robyn Guymer, Lyndell Lim, Sukhpal Sandhu, Thanh Nguyen, Dania Qatarneh, Hessom Razavi, Elaine Chong, Matthew Little, Gaurav Bhardwau, Michael Ayres, Michael Chen, Daini Ong, Katarina Creese, Tricia Drew, Carly D'Sylva Parfett, Tanya Pejnovic, Thuy Chau, Sutha Sanmugasundram, Maria Kolic, Elizabeth Glatz, Tina-Marie Tonder, Alan Luckie, Stephen Heery, Timothy Steele, Jennifer Arnold, Bryan Matthews, Julie Croft, Alex Breen, Bronwyn Gabriel, Maegan Anderson, Michelle Dodds, Marcus Dwyer, Bev Brown, Jacinta Dwyer, Ivan Fu, Helen Macauley, James Wong, Rajeev Chalasani, Charmaine Lim, Son Huynh, Timothy Nolan, James Leong, Kit Lau, Swas Kumar, Trang Nguyen, Joseph Bitar, Hannah Ahern, Arooj Ali, Nuria Zamora, Angela Lai, Randa Moussa, Carmen Do, Nitin Verma, Guy Bylsma, Andrew Traill, Beverley Curry, Amy Paprotny, Alfonso Ayesa, Alyse Johns, Zanobia Ujjainwala, Andrew Maver, Derek Chan, John Chang, Hyong Kwon Kang, Gavin Stringfellow, Terence Tan, Helen Cass, Trish Forsyth, Anh Nguyen, Angela Chung, Harriette Ayson, Catherine Severino, Caroline Chahine, Lara Collis, Anita Cristy, Mona Mohmodian, Selina Webb, Muradiya Payir, Mara Garibaldi, Trazia Mekhail, Brendan Vote, Tze'Yo Toh, Nima Pakrou, Jennie Rossetto, Shannon Harris, Rachael Adams, Rachael Groves, Maddie Johns, Kristie Richards, Eliza Jenkins, Natalie Daley, James Baker, Mark Gorbatov, Lavaniya Rajanayagam, Ludmila Jitskaia, Jenny Xie, Anthony Nguyen, Ian McAllister, Fred Chen, Tim Isaacs, Tracey-Anne Dickens, Rachel Matthews, Amelia Jason, Ivy Tang, Gareth Lingham, Holly Brown, Alla Soloshenko, Max Cuypers, Anne McSweeney, Jolly Gilhotra, Shane Durkin, James Muecke, Kerin Haywood, Cathy Brko, Rinty Vincent, Carolyn Luscombe, Alex Hunyor, Christine Younan, Robert Chong, Rohan Merani, Adrian Fung, I-Van Ho, Gerald Liew, Vinnci Lee, Gerald Chan, Sarah Liu, Tharini Ganess, Susanthy Rajasundaran, Maryam Sadat, Godfrey Quin, Stephen Ong, Claire Hooper, Vivien Dihn, Ward Al-Ghurani, Sally Ngai, Maria Choi, Gordana Tisma, Anton Van Heerden, Anthony Hall, Kira Michalova, Natalie Coleman, Allanah Price, Mercy Nguyen, Clodia Hanna, Camille Collins, Elaina Dickeson, Annie Lee, Mela Bilyk, Theresa Lee, John Downie, Naggi Assaad, Leanne Cooper, Catherine Le, Amanda Armanssen, and Zena Khalil
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medicine.medical_specialty ,Visual acuity ,genetic structures ,Bevacizumab ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Ophthalmology ,Medicine ,Prospective cohort study ,030304 developmental biology ,0303 health sciences ,medicine.diagnostic_test ,business.industry ,Retrospective cohort study ,Macular degeneration ,Fluorescein angiography ,medicine.disease ,030221 ophthalmology & optometry ,medicine.symptom ,Ranibizumab ,business ,medicine.drug - Abstract
Purpose To test the hypothesis that tolerating some subretinal fluid (SRF) in patients with neovascular age-related macular degeneration (nAMD) treated with ranibizumab using a treat-and-extend (TE intensive arm: SRF intolerant) or resolution of all IRF only (relaxed arm: SRF tolerant except for SRF >200 μm at the foveal center) before extending treatment intervals. A 5-letter noninferiority margin was applied to the primary outcome. Main Outcome Measures Mean change in best-corrected VA (BCVA), and central subfield thickness and number of injections from baseline to month 24. Results Of the 349 participants randomized (intensive arm, n = 174; relaxed arm, n = 175), 279 (79.9%) completed the month 24. The mean change in BCVA from baseline to month 24 was 3.0 letters (standard deviation, 16.3 letters) in the intensive group and 2.6 letters (standard deviation, 16.3 letters) in the relaxed group, demonstrating noninferiority of the relaxed compared with the intensive treatment (P = 0.99). Similar proportions of both groups achieved 20/40 or better VA (53.5% and 56.6%, respectively; P = 0.92) and 20/200 or worse VA (8.7% and 8.1%, respectively; P = 0.52). Participants in the relaxed group received fewer ranibizumab injections over 24 months (mean, 15.8 [standard deviation, 5.9]) than those in the intensive group (mean, 17 [standard deviation, 6.5]; P = 0.001). Significantly more participants in the intensive group never extended beyond 4-week treatment intervals (13.5%) than in the relaxed group (2.8%; P = 0.003), and significantly more participants in the relaxed group extended to and maintained 12-week treatment intervals (29.6%) than the intensive group (15.0%; P = 0.005). Conclusions Patients treated with a ranibizumab T&E protocol who tolerated some SRF achieved VA that is comparable, with fewer injections, with that achieved when treatment aimed to resolve all SRF completely.
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- 2019
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49. Communicating uncertainty in cancer prognosis: A review of web-based prognostic tools
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Luke Spooner, Stuart Peacock, Paul K. J. Han, Borsika A. Rabin, Madelaine Bell, Hannah Kay, Mark Harrison, and Nick Bansback
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Adult ,Male ,Computer science ,Risk Assessment ,Article ,Cancer prognosis ,03 medical and health sciences ,0302 clinical medicine ,Patient Education as Topic ,Neoplasms ,Humans ,Risk communication ,Web application ,030212 general & internal medicine ,Uncertainty quantification ,Internet ,business.industry ,Communication ,030503 health policy & services ,Uncertainty ,General Medicine ,Prognosis ,Precision medicine ,Data science ,Confidence interval ,Female ,Perception ,0305 other medical science ,business ,Risk assessment - Abstract
Objective To review how web-based prognosis tools for cancer patients and clinicians describe aleatory (risk estimates) and epistemic (imprecision in risk estimates) uncertainties. Methods We reviewed prognostic tools available online and extracted all uncertainty descriptions. We adapted an existing classification and classified each extracted statement by presentation of uncertainty. Results We reviewed 222 different prognostic risk tools, which produced 772 individual estimates. When describing aleatory uncertainty, almost all (90%) prognostic tools included a quantitative description, such as “chances of survival after surgery are 10%”, though there was heterogeneity in the use of percentages, natural frequencies, and use of graphics. Only 14% of tools described epistemic uncertainty. Of those that did, most used a qualitative prefix such as “about” or “up to”, while 22 tools described quantitative descriptions using confidence intervals or ranges. Conclusions Considerable heterogeneity exists in the way uncertainties are communicated in cancer prognostic tools. Few tools describe epistemic uncertainty. This variation is predominately explained by a lack of evidence and consensus in risk communication, particularly for epistemic uncertainty. Practice Implications As precision medicine seeks to improve prognostic estimates, the community may not be equipped with the tools to communicate the results accurately and effectively to clinicians and patients.
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50. Microsampling: considerations for its use in pharmaceutical drug discovery and development
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Yang Xu, Neil Spooner, Kenneth D. Anderson, Mike Lee, Joe Siple, and Enaksha R Wickremsinhe
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Pharmaceutical drug ,medicine.medical_specialty ,Bioanalysis ,Drug discovery ,business.industry ,Clinical events ,medicine.medical_treatment ,Clinical Biochemistry ,Analytic Sample Preparation Methods ,Sampling (statistics) ,General Medicine ,Specimen Handling ,Analytical Chemistry ,Medical Laboratory Technology ,Drug development ,Drug Discovery ,medicine ,Humans ,Medical physics ,General Pharmacology, Toxicology and Pharmaceutics ,business - Abstract
There is growing interest in the implementation of microsampling approaches for the quantitation of circulating concentrations of analytes in biological samples derived from nonclinical and clinical studies involved in drug development. This interest is partly due to the ethical advantages of taking smaller blood volumes, particularly for studies in rodents, children and the critically ill. In addition, these technologies facilitate sampling to be performed in previously intractable locations and occasions. Further, they enable the collection of samples for additional purposes (extra time points, biomarkers, sampling during a clinical event, etc). This article gives a comprehensive insight to the utilization of these approaches in drug discovery and development, and provides recommendations for best practice for nonclinical, clinical and bioanalytical aspects.
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- 2019
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