1. The EU Child Cohort Network's core data
- Author
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Rachel E. Foong, Marie Pedersen, Johan G. Eriksson, Barbara Heude, Faryal Zariouh, Johan Lerbech Vinther, Theano Roumeliotaki, John Wright, Veit Grote, Kathrin Guerlich, Anne-Marie Nybo Andersen, Tiffany Yang, Anne Cathrine Jørgensen, Martine Vrijheid, Ellis Voerman, Liesbeth Duijts, Marjo-Riitta Järvelin, Sido Haakma, Ahmed Elhakeem, Hazel Inskip, Angela Pinot de Moira, Maja Popovic, Sílvia Fernández-Barrés, Eva Corpeleijn, Anne Forhan, Tuija M. Mikkola, Sylvain Sebert, Morris A. Swertz, Rae-Chi Huang, Theodosia Salika, Justiina Ronkainen, Esther van Enckevort, Vincent W. V. Jaddoe, Lorenzo Richiardi, Tim Cadman, Marloes Cardol, Katrine Strandberg-Larsen, Marjolein N. Kooijman, Janine F. Felix, Marie-Aline Charles, Johanna L. Nader, Sarah Crozier, Nina Rautio, Department of Public Health [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), University Medical Center Groningen [Groningen] (UMCG), Erasmus University Medical Center [Rotterdam] (Erasmus MC), University of Bristol [Bristol], University of Southampton, University of Helsinki, Yong Loo Lin School of Medicine [Singapore], Folkhälsan Research Center, Faculty of Medecine [Helsinki], University of Helsinki-University of Helsinki, Universitat Pompeu Fabra [Barcelona] (UPF), CIBER de Epidemiología y Salud Pública (CIBERESP), Curtin University [Perth], Planning and Transport Research Centre (PATREC), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Oulu, Imperial College London, Norwegian Institute of Public Health [Oslo] (NIPH), University of Turin, University of Crete [Heraklion] (UOC), Etude longitudinale française depuis l'enfance (UMS : Ined-Inserm-EFS) (ELFE), EFS-Institut national d'études démographiques (INED)-Institut National de la Santé et de la Recherche Médicale (INSERM), European Project: 733206,H2020,H2020-SC1-2016-RTD,LIFECYCLE(2017), Pediatrics, Clinicum, Research Programs Unit, Johan Eriksson / Principal Investigator, Department of General Practice and Primary Health Care, HUS Helsinki and Uusimaa Hospital District, Faculty of Medicine, Reproductive Origins of Adult Health and Disease (ROAHD), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Università degli studi di Torino = University of Turin (UNITO), and Institut national d'études démographiques (INED)-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM)
- Subjects
0301 basic medicine ,Databases, Factual ,Epidemiology ,[SDV]Life Sciences [q-bio] ,Interoperability ,Cohort Studies ,Data harmonisation ,0302 clinical medicine ,Resource (project management) ,Medicine ,030212 general & internal medicine ,Child ,DNA METHYLATION ,Lifecourse epidemiology ,3142 Public health care science, environmental and occupational health ,Europe ,PREGNANCY ,Child, Preschool ,Cohort ,GROWTH ,HEALTH ,Public Health ,Birth cohort ,Cohort study ,Cross-cohort collaboration ,FAIR (findable, accessible, interoperable and reusable) principles ,Humans ,Information Dissemination ,DATA HARMONIZATION ,PRETERM BIRTH ,FAIR (findable ,PROFILE ,accessible ,03 medical and health sciences ,Databases ,interoperable and reusable) principles ,Product (category theory) ,Preschool ,Factual ,Protocol (science) ,business.industry ,NORWEGIAN MOTHER ,AIR-POLLUTION ,Data science ,BIRTH-WEIGHT ,Replication (computing) ,030104 developmental biology ,business ,Data Resource - Abstract
The Horizon2020 LifeCycle Project is a cross-cohort collaboration which brings together data from multiple birth cohorts from across Europe and Australia to facilitate studies on the influence of early-life exposures on later health outcomes. A major product of this collaboration has been the establishment of a FAIR (findable, accessible, interoperable and reusable) data resource known as the EU Child Cohort Network. Here we focus on the EU Child Cohort Network's core variables. These are a set of basic variables, derivable by the majority of participating cohorts and frequently used as covariates or exposures in lifecourse research. First, we describe the process by which the list of core variables was established. Second, we explain the protocol according to which these variables were harmonised in order to make them interoperable. Third, we describe the catalogue developed to ensure that the network's data are findable and reusable. Finally, we describe the core data, including the proportion of variables harmonised by each cohort and the number of children for whom harmonised core data are available. EU Child Cohort Network data will be analysed using a federated analysis platform, removing the need to physically transfer data and thus making the data more accessible to researchers. The network will add value to participating cohorts by increasing statistical power and exposure heterogeneity, as well as facilitating cross-cohort comparisons, cross-validation and replication. Our aim is to motivate other cohorts to join the network and encourage the use of the EU Child Cohort Network by the wider research community. The LifeCycle project received funding from the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 733206 LifeCycle). All study specific acknowledgements and funding are presented in the supplementary material. This manuscript reflects only the author’s view and the Commission is not responsible for any use that may be made of the information it contains.
- Published
- 2021
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