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The skipper CCD is a special type of charge coupled device in which the readout noise can be reduced to sub-electron levels by averaging independent measurements of the same charge. Thus the charge in the pixels can be determined by counting the exact number of electrons. The total readout time is proportional to the number of measurements of the charge in each pixel. For some applications this time may be too long; however, researchers usually are interested only on certain region within the matrix of pixels. In this paper we present the development of a smart skipper readout technique that allows the user to specify regions of interest of the CCD matrix where an arbitrary (high) number of measurements of the same charge can taken to obtain the desired noise level, and far less measurements are performed in those regions that are less interesting to the researcher, therefore reducing the total readout time.

We characterize the response of a novel 250 $\mu$m thick, fully-depleted Skipper Charged-Coupled Device (CCD) to visible/near-infrared light with a focus on potential applications for astronomical observations. We achieve stable, single-electron resolution with readout noise $\sigma \sim 0.18$ e$^{-}$ rms/pix from 400 non-destructive measurements of the charge in each pixel. We verify that the gain derived from photon transfer curve measurements agrees with the gain calculated from the quantized charge of individual electrons to within < 1%. We also perform relative quantum efficiency measurements and demonstrate high relative quantum efficiency at optical/near-infrared wavelengths, as is expected for a thick, fully depleted detector. Finally, we demonstrate the ability to perform multiple non-destructive measurements and achieve sub-electron readout noise over configurable subregions of the detector. This work is the first step toward demonstrating the utility of Skipper CCDs for future astronomical and cosmological applications., Comment: 14 pages, 6 figures, 2 tables