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4 results on '"Sara Giorda"'

1. Author response for 'Effectiveness of a closed‐loop control system and a virtual educational camp for children and adolescents with type 1 diabetes: a prospective multicenter real‐life study'

Author

null Valentino Cherubini, null Ivana Rabbone, null Maria Giulia Berioli, null Sara Giorda, null Donatella Lo Presti, null Giulio Maltoni, null Chiara Mameli, null Marco Marigliano, null Monica Marino, null Nicola Minuto, null Enza Mozzillo, null Elvira Piccinno, null Barbara Predieri, null Carlo Ripoli, null Riccardo Schiaffini, null Andrea Rigamonti, null Giuseppina Salzano, null Davide Tinti, null Sonia Toni, null Angela Zanfardino, null Andrea Enzo Scaramuzza, null Rosaria Gesuita, and null vEC Study Group

Subjects
Type 1 diabetes, medicine.medical_specialty, Physical medicine and rehabilitation, business.industry, medicine, medicine.disease, business, Life study
Published
2021
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2. Effectiveness of a closed-loop control system and a virtual educational camp for children and adolescents with type 1 diabetes: A prospective, multicentre, real-life study

Author

Sara Giorda, C. Ripoli, Andrea Rigamonti, Francesco Maria Rosanio, D. Lo Presti, Maria Giulia Berioli, Francesca Redaelli, Barbara Predieri, Marta Bassi, C. Carducci, M. Calandretti, Enza Mozzillo, Davide Tinti, Valentino Cherubini, Marco Marigliano, Riccardo Bonfanti, Claudio Maffeis, Giuseppina Salzano, S. Savastio, Andrea Scaramuzza, Monica Marino, Giulio Maltoni, D. Iafusco, Ivana Rabbone, C. Pigniatiello, Barbara Piccini, Stefano Zucchini, Sonia Toni, M. Trada, V. Tiberi, Fortunato Lombardo, Maurizio Delvecchio, Angela Zanfardino, Rosaria Gesuita, Nicola Minuto, Chiara Mameli, Riccardo Schiaffini, Federico Abate Daga, Elvira Piccinno, M. R. Ricciardi, P. Buzzi, Cherubini, V., Rabbone, I., Berioli, M. G., Giorda, S., Lo Presti, D., Maltoni, G., Mameli, C., Marigliano, M., Marino, M., Minuto, N., Mozzillo, E., Piccinno, E., Predieri, B., Ripoli, C., Schiaffini, R., Rigamonti, A., Salzano, G., Tinti, D., Toni, S., Zanfardino, A., Scaramuzza, A. E., Gesuita, R., Tiberi, V., Savastio, S., Pigniatiello, C., Trada, M., Zucchini, S., Redaelli, F. C., Maffeis, C., Bassi, M., Rosanio, F. M., Delvecchio, M., Buzzi, P., Ricciardi, M. R., Carducci, C., Bonfanti, R., Lombardo, F., Piccini, B., Iafusco, D., Calandretti, M., and Daga, F. A.

Subjects
Blood Glucose, medicine.medical_specialty, Glucose control, Diabetic ketoacidosis, Adolescent, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, continuous glucose monitoring, CSII, glycaemic control, insulin pump therapy, observational study, Target range, Endocrinology, Insulin Infusion Systems, Interquartile range, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Diabetes Mellitus, Humans, Hypoglycemic Agents, Insulin, Prospective Studies, Child, Type 1 diabetes, Hypoglycemic Agent, type 1 diabete, business.industry, Blood Glucose Self-Monitoring, medicine.disease, Prospective Studie, Diabetes Mellitus, Type 1, Insulin Infusion System, business, Life study, Human, Type 1
Abstract

Aim: To evaluate the impact of a virtual educational camp (vEC) on glucose control in children and adolescents with type 1 diabetes using a closed-loop control (CLC) system. Materials and Methods: This was a prospective multicentre study of children and adolescents with type 1 diabetes using the Tandem Basal-IQ system. Insulin pumps were upgraded to Control-IQ, and children and their parents participated in a 3-day multidisciplinary vEC. Clinical data, glucose metrics and HbA1c were evaluated over the 12 weeks prior to the Control-IQ update and over the 12 weeks after the vEC. Results: Forty-three children and adolescents (aged 7-16 years) with type 1 diabetes and their families participated in the vEC. The median percentage of time in target range (70-180 mg/dL; TIR) increased from 64% (interquartile range [IQR] 56%-73%) with Basal-IQ to 76% (IQR 71%-81%) with Control-IQ (P&nbsp

Published
2021

3. Tyrosine metabolism in health and disease: slow-release amino acids therapy improves tyrosine homeostasis in phenylketonuria

Author

Sara Giorda, Francesco Porta, Alberto Ponzone, and Marco Spada

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, Phenylalanine, 03 medical and health sciences, Basal (phylogenetics), Young Adult, 0302 clinical medicine, Endocrinology, Hyperphenylalaninemia, Internal medicine, Phenylketonurias, Medicine, Homeostasis, Humans, Longitudinal Studies, Tyrosine, Amino Acids, education, Child, chemistry.chemical_classification, education.field_of_study, business.industry, Phenylalanine Hydroxylase, Metabolism, medicine.disease, Prognosis, Amino acid, chemistry, Case-Control Studies, Pediatrics, Perinatology and Child Health, Dietary Supplements, Female, business, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Objectives Phenylalanine (Phe) hydroxylase (PAH) deficiency leads to hyperphenylalaninemia (HPA) and tyrosine (Tyr) depletion. We investigated Tyr homeostasis in patients with PAH deficiency and the effect of a slow-release amino acids therapy in phenylketonuria (PKU). Methods We performed four complementary investigations: (1) Tyr concentrations were monitored in 114 patients (10.6 ± 11.9 years) with PKU on dietary treatment supplemented with traditional amino acid formulations (n=52, 1175 samples) or non-PKU HPA on a free diet (n=62, 430 samples); (2) Tyr metabolism in PKU was quantitatively evaluated in three patients by a simple Tyr oral loading test (100 mg/kg); (3) diurnal and (4) long-term Tyr concentrations were evaluated in 5 and 13 patients with PKU, respectively, who switched from traditional to slow-release amino acids therapy. Results 1) Tyr concentrations in the PKU population were subnormal and significantly lower than in non-PKU HPA (p Conclusions Slow-release amino acids therapy can improve Tyr homeostasis in PKU. If associated to optimized Phe control, such a metabolic goal may allow long-term clinical benefits in patients with PKU.

Published
2020

4. Columbus' egg: a practical approach to nutritional management in maple syrup urine disease

Author

Francesco Porta, Marco Spada, Marta Busso, and Sara Giorda

Subjects
business.industry, Nutritional Support, Endocrinology, Diabetes and Metabolism, Maple syrup urine disease, Malnutrition, Infant, medicine.disease, Isovaleric Acidemia, Endocrinology, Maple Syrup Urine Disease, Valine, Pediatrics, Perinatology and Child Health, Medicine, Humans, Food science, Isoleucine, business
Published
2018

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